ORCA
Online Research @ Cardiff
Browse by Current Cardiff authors
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Up a levelNumber of items: 50.
Fielding, Ceri Alan, Sabberwal, Pragati, Williamson, James C., Greenwood, Edward J.D., Crozier, Thomas WM, Zelek, Wioleta, Seow, Jeffrey, Graham, Carl, Huettner, Isabella, Edgeworth, Jonathan D., Price, David A., Morgan, Paul B., Ladell, Kristin, Eberl, Matthias, Humphreys, Ian R., Merrick, Blair, Doores, Katie, Wilson, Sam J., Lehner, Paul J., Wang, Eddie C.Y. and Stanton, Richard J.
2022.
SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies.
eLife
11
10.7554/eLife.74489
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Wang, Eddie C.Y., Fielding, Ceri A. and Stanton, Richard J.
2022.
Concerns over functional experiments, interpretation, and required controls.
Journal of Clinical Investigation
132
(5)
, e157369.
10.1172/JCI157369
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Nightingale, Katie, Potts, Martin, Hunter, Leah M., Fielding, Ceri A., Zerbe, Cassie M., Fletcher-Etherington, Alice, Nobre, Luis, Wang, Eddie C. Y., Strang, Blair L., Houghton, Jack W., Antrobus, Robin, Suarez, Nicolas M., Nichols, Jenna, Davison, Andrew J., Stanton, Richard J. and Weekes, Michael P.
2022.
Human cytomegalovirus protein RL1 degrades the antiviral factor SLFN11 via recruitment of the CRL4 E3 ubiquitin ligase complex.
Proceedings of the National Academy of Sciences
119
(6)
, e2108173119.
10.1073/pnas.2108173119
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Elasifer, Hana, Wang, Eddie C.Y., Prod'homme, Virginie, Davies, James, Forbes, Simone, Stanton, Richard J., Patel, Mihil, Fielding, Ceri A., Roberts, Dawn, Traherne, James A., Gruber, Nicole, Bugert, Joachim J., Aicheler, Rebecca J. and Wilkinson, Gavin W. G.
2020.
Downregulation of HLA-I by the molluscum contagiosum virus mc080 impacts NK-cell recognition and promotes CD8+ T-cell evasion.
Journal of General Virology
101
, pp. 863-872.
10.1099/jgv.0.001417
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| Patel, Mihil, Vlachava, Virginia-Maria, Forbes, Simone K., Fielding, Ceri A., Stanton, Richard J. and Wang, Edward 2018. HCMV-encoded NK modulators: Lessons from in vitro and in vivo genetic variation. Frontiers in Immunology 9 , 2214. 10.3389/fimmu.2018.02214 |
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Nightingale, Katie, Lin, Kai-Min, Ravenhill, Benjamin J., Davies, Colin, Nobre, Luis, Fielding, Ceri A., Ruckova, Eva, Fletcher-Etherington, Alice, Soday, Lior, Nichols, Hester, Sugrue, Daniel, Wang, Eddie C.Y., Moreno, Pablo, Umrania, Yagnesh, Huttlin, Edward L., Antrobus, Robin, Davison, Andrew J., Wilkinson, Gavin W.G., Stanton, Richard J., Tomasec, Peter and Weekes, Michael P.
2018.
High-definition analysis of host protein stability during human cytomegalovirus infection reveals antiviral factors and viral evasion mechanisms.
Cell Host and Microbe
24
(3)
, 447-460.e11.
10.1016/j.chom.2018.07.011
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| Wang, Eddie C. Y., Pjechova, Marina, Nightingale, Katie, Vlachava, Virginia-Maria, Patel, Mihil, Ruckova, Eva, Forbes, Simone K., Nobre, Luis, Antrobus, Robin, Roberts, Dawn, Fielding, Ceri A., Seirafian, Sepehr, Davies, James, Murrell, Isa, Lau, Betty, Wilkie, Gavin S., Suarez, Nicolas M., Stanton, Richard J., Vojtesek, Borivoj, Davison, Andrew, Lehner, Paul J., Weekes, Michael P., Wilkinson, Gavin W. G. and Tomasec, Peter 2018. Suppression of costimulation by human cytomegalovirus promotes evasion of cellular immune defenses. Proceedings of the National Academy of Sciences 115 (19) , pp. 4998-5003. 10.1073/pnas.1720950115 |
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Stacey, Maria A., Clare, Simon, Clement, Mathew, Marsden, Morgan, Abdul-Karim, Juneid, Kane, Leanne, Harcourt, Katherine, Brandt, Cordelia, Fielding, Ceri A., Smith, Sarah E., Wash, Rachael S., Gimeno Brias, Silvia, Stack, Gabrielle, Notley, George, Cambridge, Emma L., Isherwood, Christopher, Speak, Anneliese O., Johnson, Zoe, Ferlin, Walter, Jones, Simon A., Kellam, Paul and Humphreys, Ian R.
2017.
The antiviral restriction factor IFN-induced transmembrane protein 3 prevents cytokine-driven CMV pathogenesis.
Journal of Clinical Investigation
127
(4)
, pp. 1463-1474.
10.1172/JCI84889
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| Fielding, Ceri A., Weekes, Michael P., Nobre, Luis V., Ruckova, Eva, Wilkie, Gavin S., Paulo, Joao A., Chang, Chiwen, Suárez, Nicolás M., Davies, James A., Antrobus, Robin, Stanton, Richard J., Aicheler, Rebecca J, Nichols, Hester, Vojtesek, Borek, Trowsdale, John, Davison, Andrew J., Gygi, Steven P., Tomasec, Peter, Lehner, Paul J. and Wilkinson, Gavin W. G. 2017. Control of immune ligands by members of a cytomegalovirus gene expansion suppresses natural killer cell activation. eLife 6 , e22206. 10.7554/eLife.22206 |
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Murrell, Isa, Wilkie, Gavin S., Davison, Andrew J., Statkute, Evelina, Fielding, Ceri A., Tomasec, Peter, Wilkinson, Gavin W. G. and Stanton, Richard J.
2016.
Genetic stability of BAC-deerived human cytomegalovirus during culture in vitro.
Journal of Virology
90
(8)
, pp. 3929-3943.
10.1128/JVI.02858-15
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| Wilkinson, Gavin William Grahame, Davison, Andrew J., Tomasec, Peter, Fielding, Ceri Alan, Aicheler, Rebecca, Murrell, Isa, Seirafian, Sepher, Wang, Edward Chung Yern, Weekes, Michael, Lehner, Paul J., Wilkie, Gavin S. and Stanton, Richard James 2015. Human cytomegalovirus: taking the strain. Medical Microbiology and Immunology 204 (3) , pp. 273-284. 10.1007/s00430-015-0411-4 |
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| Fielding, Ceri Alan 2015. Mimicry of cytokine pathways by human herpesviruses. Future Virology 10 (1) , pp. 41-51. 10.2217/fvl.14.101 |
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| Weekes, Michael P., Tomasec, Peter, Huttlin, Edward L., Fielding, Ceri A., Nusinow, David, Stanton, Richard J., Wang, Eddie C. Y., Aicheler, Rebecca, Murrell, Isa, Wilkinson, Gavin W. G., Lehner, Paul J. and Gygi, Steven P. 2014. Quantitative temporal viromics: an approach to investigate host-pathogen interaction. Cell 157 (6) , pp. 1460-1472. 10.1016/j.cell.2014.04.028 |
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| Fielding, Ceri A., Aicheler, Rebecca, Stanton, Richard J., Wang, Eddie C. Y., Han, Song, Seirafian, Sepehr, Davies, James, McSharry, Brian P., Weekes, Michael P., Antrobus, P. Robin, Prod'homme, Virginie, Blanchet, Fabien P., Sugrue, Daniel M., Cuff, Simone, Roberts, Dawn, Davison, Andrew J., Lehner, Paul J., Wilkinson, Gavin W. G. and Tomasec, Peter 2014. Two novel human cytomegalovirus NK cell evasion functions target MICA for lysosomal degradation. PLoS Pathogens 10 (5) , e1004058. 10.1371/journal.ppat.1004058 |
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| Seirafian, Sepher, Prod'homme, Virginie, Sugrue, Daniel, Davies, James, Fielding, Ceri, Tomasec, Peter and Wilkinson, Gavin W. G. 2014. Human cytomegalovirus suppresses Fas expression and function. Journal of General Virology 95 (4) , pp. 933-939. 10.1099/vir.0.058313-0 |
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| Jones, Simon Arnett, Fraser, Donald James, Fielding, Ceri Alan and Jones, Gareth Wyn 2014. Interleukin-6 in renal disease and therapy. Nephrology Dialysis Transplantation 30 (4) , pp. 564-574. 10.1093/ndt/gfu233 |
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Fielding, Ceri A., Jones, Gareth W., McLoughlin, Rachel M., McLeod, Louise, Hammond, Victoria J., Uceda, Javier, Williams, Anwen S., Lambie, Mark, Foster, Thomas L., Liao, Chia-Te, Rice, Christopher M., Greenhill, Claire J., Colmont, Chantal S., Hams, Emily, Coles, Barbara, Kift-Morgan, Ann, Newton, Zarabeth, Craig, Katherine J., Williams, John D., Williams, Geraint T., Davies, Simon J., Humphreys, Ian R., O'Donnell, Valerie B., Taylor, Philip R., Jenkins, Brendan J., Topley, Nicholas and Jones, Simon A.
2014.
Interleukin-6 signaling drives fibrosis in unresolved inflammation.
Immunity
40
(1)
, pp. 40-50.
10.1016/j.immuni.2013.10.022
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| Lauder, Sarah Nicol, Jones, Emma, Smart, Kathryn, Bloom, Anja Constanze, Williams, Anwen Sian, Hindley, James P., Ondondo, Beatrice, Taylor, Philip Russel, Clement, Mathew, Fielding, Ceri Alan, Godkin, Andrew James, Jones, Simon Arnett and Gallimore, Awen Myfanwy 2013. Interleukin-6 limits influenza-induced inflammation and protects against fatal lung pathology. European Journal of Immunology 43 (10) , pp. 2613-2625. 10.1002/eji.201243018 |
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| Fielding, Ceri Alan, Jones, Gareth Wyn, Taylor, Philip Russel, Jenkins, Brendan J., Topley, Nicholas and Jones, Simon Arnett 2013. IL-6 regulation of Th1 responses drives fibrosis in unresolved inflammation [Abstract]. Cytokine 63 (3) , p. 262. 10.1016/j.cyto.2013.06.082 |
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| Pembroke, Thomas, Rees, Ian W., Gallagher, Kathleen, Jones, Emma, Mizen, Paul Edward, Navruzov, Timur, Freedman, Andrew Robert, Fielding, Ceri Alan, Humphreys, Ian R., Wang, Edward Chung Yern, Gallimore, Awen Myfanwy and Godkin, Andrew James 2012. Rapid early innate control of hepatitis C virus during IFN-α treatment compromises adaptive CD4+T-cell immunity. European Journal of Immunology 42 (9) , pp. 2383-2394. 10.1002/eji.201142072 |
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| Fielding, Ceri Alan, Seirafian, Sepher, Davies, James Anthony, Cuff, Simone, Aicheler, Rebecca, Sugrue, Daniel M., Davison, A., Stanton, Richard James, Wilkinson, Gavin William Grahame and Tomasec, Peter 2012. A novel human cytomegalovirus gene function targets the natural killer cell activating ligand MICA for lysosomal degradation [Abstract]. Immunology 137 (S1) , p. 154. 10.1111/imm.12001 |
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| Fielding, Ceri Alan 2012. Interleukin-19: a new target to aim for? Rheumatology 51 (3) , pp. 399-400. 10.1093/rheumatology/ker174 |
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| Colmont, Chantal Sophie, Raby, Anne-Catherine, Dioszeghy, Vincent, Le Bouder, Emmanuel, Foster, Thomas Lloyd, Jones, Simon Arnett, Labeta, Mario Oscar, Fielding, Ceri Alan and Topley, Nicholas 2011. Human peritoneal mesothelial cells respond to bacterial ligands through a specific subset of Toll-like receptors. Nephrology Dialysis Transplantation 26 (12) , pp. 4079-4090. 10.1093/ndt/gfr217 |
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| Lin, Chan-Yu, Roberts, Gareth W., Davey, Martin S., Chess, James Anthony, Fielding, Ceri Alan, Williams, John David, Davies, S. J., Johnson, D. W., Moser, Bernhard, Topley, Nicholas and Eberl, Matthias 2010. The HMB-PP producing capacity of the causative pathogen and local gamma delta T cell numbers predict clinical outcome from bacterial peritonitis. Immunology 131 , pp. 81-82. |
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| Stumhofer, Jason S., Tait, Elia D., III, William J. Quinn, Hosken, Nancy, Spudy, Björn, Goenka, Radhika, Fielding, Ceri Alan, O'Hara, Aisling C., Chen, Yi, Jones, Michael L., Saris, Christiaan J. M., Rose-John, Stefan, Cua, Daniel J., Jones, Simon Arnett, Elloso, Merle M., Grötzinger, Joachim, Cancro, Michael P., Levin, Steven D. and Hunter, Christopher A. 2010. A role for IL-27p28 as an antagonist of gp130-mediated signaling. Nature Immunology 11 (12) , pp. 1119-1126. 10.1038/ni.1957 |
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| Coles, Barbara, Colmont, Chantal Sophie, Fielding, Ceri Alan, Kift-Morgan, Ann, Hams, Emily, Topley, Nicholas and Jones, Simon Arnett 2010. Local manipulation of IL-6 trans-signaling therapeutically enhances anti-microbial host defense [Abstract]. Cytokine 52 (1-2) , pp. 80-81. 10.1016/j.cyto.2010.07.335 |
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| Li, Na, McLaren, James Edward, Michael, Daryn Robert, Clement, Mathew, Fielding, Ceri Alan and Ramji, Dipak Purshottam 2010. ERK is integral to the IFN-γ-mediated activation of STAT1, the expression of key genes implicated in atherosclerosis, and the uptake of modified lipoproteins by human macrophages. The Journal of Immunology 185 (5) , pp. 3041-3048. 10.4049/jimmunol.1000993 |
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| Luo, Dong Dong, Fielding, Ceri Alan, Phillips, Aled Owain and Fraser, Donald James 2009. Interleukin-1 beta regulates proximal tubular cell transforming growth factor beta-1 signalling. Nephrology Dialysis Transplantation 24 (9) , pp. 2655-2665. 10.1093/ndt/gfp208 |
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| Rabe, B., Chalaris, A., Adams, N., Paliga, K., Lange, H., Laskay, T., Fielding, Ceri Alan, Waetzig, G. H., Seegert, D., Williams, Anwen Sian, Jones, Simon Arnett, Sina, C., Rose-John, Stefan and Schelle, J. 2008. The role of IL6-transsignaling in acute and chronic inflammation [Abstract]. Cytokine 43 (3) , p. 244. 10.1016/j.cyto.2008.07.073 |
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| Jenkins, Brendan J., Nadjovska, Meri, Greenhill, Claire, McLeod, Louise, Tye, Hazel, Kennedy, Catherine, Fielding, Ceri Alan, Topley, Nicholas, Jones, Simon Arnett, Ernst, Matthias and Hertzog, Paul J. 2008. Differential roles of IL-6 and IL-11 in inflammation and tumorigenesis [Abstract]. Cytokine 43 (3) , p. 243. 10.1016/j.cyto.2008.07.069 |
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| Hams, Emily, Colmont, Chantal Sophie, Dioszeghy, Vincent, Hammond, Victoria Jayne, Fielding, Ceri Alan, Williams, Anwen Sian, Tanaka, Minoru, Miyajima, Atsushi, Taylor, Philip Russel, Topley, Nicholas and Jones, Simon Arnett 2008. Oncostatin M receptor-β signaling limits monocytic cell recruitment in acute inflammation. Journal of Immunology 181 (3) , pp. 2174-2180. |
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| Fielding, Ceri Alan, McLoughlin, Rachel Mary, McLeod, Louise, Colmont, Chantal Sophie, Najdovska, Meri, Grail, Dianne, Ernst, Matthias, Jones, Simon Arnett, Topley, Nicholas and Jenkins, Brendan J. 2008. IL-6 regulates neutrophil trafficking during acute inflammation via STAT3. Journal of Immunology 181 (3) , pp. 2189-2195. |
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| Hams, Emily, Colmont, Chantal S., Dioszeghy, Vincent, Hammond, Victoria Jayne, Fielding, Ceri Alan, Williams, Anwen Sian, Tanaka, Minoru, Miyajima, Atsushi, Taylor, Philip Russel, Topley, Nicholas and Jones, Simon Arnett 2008. Oncostatin M receptor-beta signaling limits monocytic cell recruitment in acute inflammation. Journal of Immunology 181 (3) , pp. 2174-2180. |
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| Fielding, Ceri Alan and Topley, Nicholas 2008. Piece by piece: solving the puzzle of peritoneal fibrosis [Commentary]. Peritoneal Dialysis International 28 (5) , pp. 477-479. |
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| Chalaris, A., Rabe, B., Paliga, K., Lange, H., Laskay, T., Fielding, Ceri Alan, Jones, S. A., Rose-John, S. and Scheller, J. 2007. Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils. Blood -New York- 110 (6) , pp. 1748-1755. 10.1182/blood-2007-01-067918 |
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| Rabe, B., Chalaris, Athena, May, Ulrike, Paliga, Krzysztof, Lange, Hans, Laskay, Tamas, Fielding, Ceri Alan, Waetzig, Georg H., Seegert, Dirk, Williams, Anwen Sian, Jones, Simon Arnett, Rose-John, Stefan and Scheller, J. 2007. IL6/sIL6R-transsignaling controls innate and aquired immunity [Abstract]. Cytokine 39 (1) , p. 34. 10.1016/j.cyto.2007.07.129 |
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| Hams, Emily, Dioszechy, Vincent, Colmont, Chantal Sophie, Hammond, Victoria Jayne, Fielding, Ceri Alan, Williams, Anwen Sian, Tanaka, Minoru, Miyajima, Atsushi, Taylor, Philip Russel, Topley, Nicholas and Jones, Simon Arnett 2007. Oncostatin M receptor signalling regulates monocytic cell trafficking during acute inflammation [Abstract]. Cytokine 39 (1) , p. 14. 10.1016/j.cyto.2007.07.053 |
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| Coles, Barbara, Fielding, Ceri Alan, Rose-John, Stefan, Scheller, J., Jones, S. A. and O'Donnell, Valerie Bridget 2007. Classic interleukin-6 receptor signaling and interleukin-6 trans-signaling differentially control angiotensin II-dependent hypertension, cardiac signal transducer and activator of transcription-3 activation, and vascular hypertrophy in vivo. American Journal of Pathology 171 (1) , pp. 315-325. 10.2353/ajpath.2007.061078 |
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| Nowell, Mari Ann, Richards, Peter James, Fielding, Ceri Alan, Ognjanovic, Simona, Topley, Nicholas, Williams, Anwen Sian, Bryant-Greenwood, Gillian and Jones, Simon Arnett 2006. Regulation of pre-B cell colony-enhancing factor by STAT-3-dependent interleukin-6 trans-signaling: implications in the pathogenesis of rheumatoid arthritis. Arthritis & Rheumatism 54 (7) , pp. 2084-2095. 10.1002/art.21942 |
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| Monslow, Jamie, Williams, John David, Fraser, Donald James, Michael, Daryn Robert, Foka, Pelagia, Kift-Morgan, Ann Patricia, Luo, Dong Dong, Fielding, Ceri Alan, Craig, Kathrine Jane, Topley, Nicholas, Jones, Simon Arnett, Ramji, Dipak Purshottam and Bowen, Timothy 2006. Sp1 and Sp3 mediate constitutive transcription of the human hyaluronan synthase 2 gene. The Journal of Biological Chemistry 281 (26) , pp. 18043-18050. 10.1074/jbc.M510467200 |
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| Osborne, C. S., Leitner, I., Hofbauer, B., Fielding, Ceri Alan, Favre, B. and Ryder, N. S. 2006. Biological, biochemical, and molecular characterization of a new clinical Trichophyton rubrum isolate resistant to terbinafine. Antimicrobial Agents and Chemotherapy 50 (6) , pp. 2234-2236. 10.1128/AAC.01600-05 |
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| Richards, Peter James, Nowell, Mari Ann, Horiuchi, Sankichi, McLoughlin, Rachel Mary, Fielding, Ceri Alan, Grau, Sandra, Yamamoto, Naoki, Ehrmann, Michael, Rose-John, Stefan, Williams, Anwen Sian, Topley, Nicholas and Jones, Simon Arnett 2006. Functional characterization of a soluble gp130 isoform and its therapeutic capacity in an experimental model of inflammatory arthritis. Arthritis & Rheumatism 54 (5) , pp. 1662-1672. 10.1002/art.21818 |
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| Fielding, Ceri Alan, McLoughlin, Rachel Mary, Colmont, Chantal Sophie, Kovaleva, Marina, Harris, Dean Anthony, Rose-John, Stefan, Topley, Nicholas and Jones, Simon Arnett 2005. Viral IL-6 blocks neutrophil infiltration during acute inflammation. The Journal of Immunology 175 (6) , pp. 4024-4029. |
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| Siebert, Stefan, Fielding, Ceri A., Williams, Bryan D. and Brennan, Paul 2005. Mutation of the extracellular domain of tumour necrosis factor receptor 1 causes reduced NF‐κB activation due to decreased surface expression. FEBS Letters 579 (23) , pp. 5193-5198. 10.1016/j.febslet.2005.08.037 |
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| McLoughlin, Rachel Mary, Jenkins, Brendan J., Grail, Dianne, Williams, Anwen Sian, Fielding, Ceri Alan, Parker, Clare R., Ernst, Matthias, Topley, Nicholas and Jones, Simon Arnett 2005. IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation. Proceedings of the National Academy of Sciences of the United States of America (PNAS) ISSN 1091-6490 102 (27) , pp. 9589-9594. 10.1073/pnas.0501794102 |
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| Siebert, Stefan, Amos, Nick, Fielding, Ceri Alan, Wang, Edward Chung Yern, Aksentijevich, Ivona, Williams, Bryan Davies and Brennan, Paul 2005. Reduced tumor necrosis factor signaling in primary human fibroblasts containing a tumor necrosis factor receptor superfamily 1A mutant. Arthritis & Rheumatism 52 (4) , pp. 1287-1282. 10.1002/art.20955 |
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| Fielding, Ceri Alan, Siebert, Stefan, Rowe, Martin and Brennan, Paul 2004. Analysis of human tumour necrosis factor receptor 1 dominant-negative mutants reveals a major region controlling cell surface expression. FEBS Letters 570 (1-3) , pp. 138-142. 10.1016/j.febslet.2004.06.035 |
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| Richardson, Ciaran Joseph, Fielding, Ceri, Rowe, Martin and Brennan, Paul 2003. Epstein-Barr virus regulates STAT1 through latent membrane protein 1. Journal of Virology 77 (7) , pp. 4439-4443. 10.1128/JVI.77.7.4439-4443.2003 |
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| Fielding, Ceri Alan, Sandvej, Kristian, Mehl, Anja Maria, Brennan, Paul, Jones, Matthew and Rowe, Martin 2001. Epstein-Barr virus LMP-1 natural sequence variants differ in their potential to activate cellular signaling pathways. Journal of Virology 75 (19) , pp. 9129-9141. 10.1128/JVI.75.19.9129-9141.2001 |
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