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Number of items: 75.

Lu, Yueh-An, Smith, Tanya, Deshpande, Sumukh, Liao, Chia-Te, Talabani, Bnar, Grigorieva, Irina, Mason, Anna, Andrews, Robert, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421 and Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 2024. Sex-specific proximal tubular cell differentiation pathways identified by single-nucleus RNA sequencing. Scientific Reports 14 (1) , 24041. 10.1038/s41598-024-73102-7
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Smith, Tanya, Zaidi, Aeliya, Brown, Charlotte Victoria Maynard, Pino-Chavez, Gilda, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342, Chavez, Rafael and Khalid, Usman 2024. Robust rat and mouse models of bilateral renal ischemia reperfusion injury. In Vivo 38 (3) , pp. 1049-1057. 10.21873/invivo.13538
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Smith, Daniel A. ORCID: https://orcid.org/0000-0003-3145-3160, Redman, James E. ORCID: https://orcid.org/0000-0001-5492-2869, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2023. Identification and detection of microRNA kidney disease biomarkers in liquid biopsies. Current Opinion in Nephrology and Hypertension 32 (6) , pp. 515-521. 10.1097/MNH.0000000000000927
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Grigorieva, Irina, Woods, Emma L., Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978 2023. Hyaluronan in kidney fibrosis. Passi, Alberto, ed. Hyaluronan: Structure, Biology and Biotechnology, Vol. 14. Biology of Extracellular Matrix, Springer, pp. 77-97. (10.1007/978-3-031-30300-5_5)

Wonnacott, Alexa ORCID: https://orcid.org/0000-0002-0968-4248, Denby, Laura, Coward, Richard J. M., Fraser, Donald J. and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2022. MicroRNAs and their delivery in diabetic fibrosis. Advanced Drug Delivery Reviews 182 , 114045. 10.1016/j.addr.2021.114045
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Lu, Yueh-An, Liao, Chia-Te, Raybould, Rachel, Talabani, Bnar, Grigorieva, Irina, Szomolay, Barbara ORCID: https://orcid.org/0000-0002-5375-5533, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Andrews, Robert, Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421 and Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 2021. Single-nucleus RNA sequencing identifies new classes of proximal tubular epithelial cells in kidney fibrosis. Journal of the American Society of Nephrology 32 (10) , pp. 2501-2516. 10.1681/ASN.2020081143
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Woods, Emma L., Grigorieva, Irina V., Midgley, Adam C., Brown, Charlotte V.M., Lu, Yueh-an, Phillips, Aled O. ORCID: https://orcid.org/0000-0001-9744-7113, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978 and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 2021. CD147 mediates the CD44s-dependent differentiation of myofibroblasts driven by transforming growth factor-β1. Journal of Biological Chemistry 297 (3) , 100987. 10.1016/j.jbc.2021.100987
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Newbury, Lucy J., Simpson, Kate, Khalid, Usman, John, Imogen, de Rivera, Lluís Bailach, Lu, Yueh-An, Lopez-Anton, Melisa, Watkins, William J. ORCID: https://orcid.org/0000-0003-3262-6588, Jenkins, Robert H. ORCID: https://orcid.org/0000-0001-8500-9044, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2021. miR-141 mediates recovery from acute kidney injury. Scientific Reports 11 (1) , 16499. 10.1038/s41598-021-94984-x
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Smith, Daniel A. ORCID: https://orcid.org/0000-0003-3145-3160, Simpson, Kate, Lo Cicero, Matteo, Newbury, Lucy J., Nicholas, Philip, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342, Caiger, Nigel, Redman, James E. ORCID: https://orcid.org/0000-0001-5492-2869 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2021. Detection of urinary microRNA biomarkers using diazo sulfonamide-modified screen printed carbon electrodes. RSC Advances 11 (31) , pp. 18832-18839. 10.1039/D0RA09874D
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Khalid, Usman, Jenkins, Robert H. ORCID: https://orcid.org/0000-0001-8500-9044, Andrews, Robert, Pino-Chavez, Gilda, Cossins, Benjamin C., Chavez, Rafael, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342 2021. Determination of a microRNA signature of protective kidney ischemic preconditioning originating from proximal tubules. Scientific Reports 11 (1) , 9862. 10.1038/s41598-021-89195-3
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Brook, Amy C., Jenkins, Robert H. ORCID: https://orcid.org/0000-0001-8500-9044, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Kift-Morgan, Ann, Raby, Anne-Catherine ORCID: https://orcid.org/0000-0002-5354-5835, Shephard, Alex P., Mariotti, Barbara, Cuff, Simone M. ORCID: https://orcid.org/0000-0002-0546-3579, Bazzoni, Flavia, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342 and Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348 2019. Neutrophil-derived miR-223 as local biomarker of bacterial peritonitis. Scientific Reports 9 , 10136. 10.1038/s41598-019-46585-y
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Khalid, Usman, Newbury, Lucy J., Simpson, Kate, Jenkins, Robert H. ORCID: https://orcid.org/0000-0001-8500-9044, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Bates, Lucy, Sheerin, Neil S., Chavez, Rafael and Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342 2019. A urinary microRNA panel that is an early predictive biomarker of delayed graft function following kidney transplant. Scientific Reports 9 , 3584. 10.1038/s41598-019-38642-3
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Thomas, Melissa, Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2018. Biogenesis, stabilization, and transport of microRNAs in kidney health and disease. Non-Coding RNA 4 (4) , p. 30. 10.3390/ncrna4040030
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Beltrami, Cristina, Simpson, Kate, Jesky, Mark, Wonnacott, Alexa ORCID: https://orcid.org/0000-0002-0968-4248, Carrington, Christopher, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, Newbury, Lucy, Jenkins, Robert ORCID: https://orcid.org/0000-0001-8500-9044, Ashdown, Thomas, Dayan, Colin ORCID: https://orcid.org/0000-0002-6557-3462, Satchell, Simon, Corish, Peter, Cockwell, Paul, Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2018. Association of elevated urinary miR-126, miR-155, and miR-29b with diabetic kidney disease. American Journal of Pathology 188 (9) , pp. 1982-1992. 10.1016/j.ajpath.2018.06.006
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Smith, Daniel ORCID: https://orcid.org/0000-0003-3145-3160, Newbury, Lucy, Drago, Guido, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Redman, James Edward ORCID: https://orcid.org/0000-0001-5492-2869 2017. Electrochemical detection of urinary microRNAs via sulfonamide-bound antisense hybridisation. Sensors and Actuators B: Chemical 253 , pp. 335-341. 10.1016/j.snb.2017.06.069
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Wonnacott, Alexa ORCID: https://orcid.org/0000-0002-0968-4248, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 2017. MicroRNAs as biomarkers in chronic kidney disease. Current Opinion in Nephrology and Hypertension 26 (6) , pp. 460-466. 10.1097/MNH.0000000000000356
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Lopez-Anton, Melisa, Lambie, Mark, Lopez-Cabrera, Manuel, Schmitt, Claus P., Ruiz-Carpio, Vicente, Bartosova, Maria, Schaefer, Betti, Davies, Simon, Stone, Timothy ORCID: https://orcid.org/0000-0003-4591-9611, Jenkins, Robert ORCID: https://orcid.org/0000-0001-8500-9044, Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421, Topley, Nicholas, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 2017. miR-21 promotes fibrogenesis in peritoneal dialysis. American Journal of Pathology 187 (7) , pp. 1537-1550. 10.1016/j.ajpath.2017.03.007
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Lopez Anton, Melisa, Rudolf, Andras, Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Roger, Laureline, Robinson, Rhiannon, Witowski, Janusz, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2017. Telomere length profiles in primary human peritoneal mesothelial cells are consistent with senescence. Mechanisms of Ageing and Development 164 , pp. 37-40. 10.1016/j.mad.2017.03.010
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Liuzzi, Anna Rita, Kift-Morgan, Ann, Lopez-Anton, Melisa, Friberg, Ida M., Zhang, Jingjing ORCID: https://orcid.org/0000-0002-8970-7568, Brook, Amy C., Roberts, Gareth W., Donovan, Kieron L., Colmont, Chantal S., Toleman, Mark A., Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Johnson, David W., Topley, Nicholas, Moser, Bernhard ORCID: https://orcid.org/0000-0002-4354-4572, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342 and Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348 2016. Unconventional human T cells accumulate at the site of infection in response to microbial ligands and induce local tissue remodeling. Journal of Immunology 197 (6) , pp. 2195-2207. 10.4049/jimmunol.1600990
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Martin, John, Midgley, Adam, Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Woods, Emma, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Phillips, Aled O. ORCID: https://orcid.org/0000-0001-9744-7113 and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 2016. Tumour necrosis factor-stimulated gene (TSG)-6-mediated interactions with the inter-alpha-inhibitor heavy chain 5 facilitate TGF beta1-dependent fibroblast to myofibroblast differentiation. Journal of Biological Chemistry 291 , pp. 13789-13801. 10.1074/jbc.M115.670521
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Simpson, Katherine, Wonnacott, Alexa ORCID: https://orcid.org/0000-0002-0968-4248, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2016. MicroRNAs in diabetic nephropathy: from biomarkers to therapy. Current Diabetes Reports 16 (3) , 35. 10.1007/s11892-016-0724-8
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Khalid, Usman, Ablorsu, Elijah, Szabo, Laszlo, Jenkins, Robert H. ORCID: https://orcid.org/0000-0001-8500-9044, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Chavez, Rafael and Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342 2016. MicroRNA-21 (miR-21) expression in hypothermic machine perfusate may be predictive of early outcomes in kidney transplantation. Clinical Transplantation 30 (2) , pp. 99-104. 10.1111/ctr.12679

Chavez, Rafael, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Nesargikar, Prabhu, Pino-Chavez, Gilda and Khalid, Usman 2016. Kidney ischaemia reperfusion injury in the rat: the EGTI scoring system as a valid and reliable tool for histological assessment. Journal of Histology and Histopathology 3 , 1. 10.7243/2055-091X-3-1
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Khalid, Usman, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Simpson, Katherine, Ablorsu, Elijah, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Chavez, Rafael 2015. Urinary microrna expression predicts delayed graft function in kidney transplantation [Abstract]. Transplant International 28 (S4) , p. 367. 10.1111/tri.12702

Beltrami, Cristina, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Newbury, Lucy, Corish, Peter, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2015. Stabilization of urinary microRNAs by association with exosomes and argonaute 2 protein. Non-Coding RNA 1 (2) , pp. 151-166. 10.3390/ncrna1020151
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Jenkins, Robert ORCID: https://orcid.org/0000-0001-8500-9044, Liao, Chia-Te, Wallace, Leah, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Topley, Nicholas, Taylor, Philip ORCID: https://orcid.org/0000-0003-0163-1421 and Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 2015. Microrna regulation of macrophage phenotype in peritoneal fibrosis. Nephrology Dialysis Transplantation 30 (iii262) 10.1093/ndt/gfv180.15

Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Williams, Aled ORCID: https://orcid.org/0000-0002-6800-8135, Newbury, Lucy, Sauter, Matthias and Sitter, Thomas 2015. Regulation of synthesis and roles of hyaluronan in peritoneal dialysis. BioMed Research International 2015 , 427038. 10.1155/2015/427038
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Vigetti, Davide, Deleonibus, Sara, Moretto, Paola, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Fischer, Jens W., Grandoch, Maria, Oberhuber, Alexander, Love, Dona C., Hanover, John A., Cinquetti, Raffaella, Karousou, Eugenia, Viola, Manuela, D'Angelo, Maria Luisa, Hascall, Vincent C., De Luca, Giancarlo and Passi, Alberto 2014. Natural antisense transcript for hyaluronan synthase 2 (HAS2-AS1) induces transcription of HAS2 via protein O-GlcNAcylation. Journal of Biological Chemistry 289 (42) , pp. 28816-28826. 10.1074/jbc.M114.597401

Khalid, Usman, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 and Jenkins, Robert ORCID: https://orcid.org/0000-0001-8500-9044 2014. Acute kidney injury: a paradigm for miRNA regulation of the cell cycle. Biochemical Society Transactions 42 (4) , pp. 1219-1223. 10.1042/BST20140093

Midgley, Adam C., Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Phillips, Aled O. ORCID: https://orcid.org/0000-0001-9744-7113 and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 2014. MicroRNA-7 inhibition rescues age-associated loss of epidermal growth factor receptor and hyaluronan-dependent differentiation in fibroblasts. Aging Cell 13 (2) , pp. 235-244. 10.1111/acel.12167
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Jenkins, Robert H. ORCID: https://orcid.org/0000-0001-8500-9044, Davies, Luke C., Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421, Akiyama, Hideo, Cumbes, Bevan ORCID: https://orcid.org/0000-0001-8529-0040, Beltrami, Cristina, Carrington, Christopher P., Phillips, Aled O. ORCID: https://orcid.org/0000-0001-9744-7113, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342 2014. miR-192 induces G2/M growth arrest in aristolochic acid nephropathy. American Journal of Pathology 184 (4) , pp. 996-1009. 10.1016/j.ajpath.2013.12.028

Benitez, Anaid, Yates, Travis J., Shamaldevi, N., Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Lokeshwar, Vinata B. 2013. Dietary supplement hymecromone and sorafenib: A novel combination for the control of renal cell carcinoma. The Journal of Urology 190 (1) , pp. 285-290. 10.1016/j.juro.2012.12.011

Midgley, Adam Christopher, Rogers, Mathew James, Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 2013. Transforming growth factor-β1 (TGF-β1)-stimulated fibroblast to myofibroblast differentiation Is mediated by hyaluronan (HA)-facilitated epidermal growth factor receptor (EGFR) and CD44 co-localization in lipid rafts. Journal of Biological Chemistry 288 (21) , pp. 14824-14838. 10.1074/jbc.M113.451336

Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2013. MicroRNAs, transforming growth factor Beta-1, and tissue fibrosis. The Journal of Pathology 229 (2) , pp. 274-285. 10.1002/path.4119

Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Martin, John, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2012. Transforming growth factor β1 represses proximal tubular cell microRNA-192 expression through decreased hepatocyte nuclear factor DNA binding. Biochemical Journal 443 (2) , pp. 407-416. 10.1042/BJ20111861

Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2012. A role for fibrocytes in peritoneal fibrosis? Peritoneal Dialysis International 32 (1) , pp. 4-6. 10.3747/pdi.2011.00071

Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Martin, John, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2012. Pleiotropy of microRNA-192 in the kidney. Biochemical Society Transactions 40 (4) , pp. 762-767. 10.1042/BST20120085

Beltrami, Cristina, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2012. Analysis of urinary microRNAs in chronic kidney disease. Biochemical Society Transactions 40 (4) , pp. 875-879. 10.1042/BST20120090

Michael, Daryn Robert, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Krupa, Aleksandra, Martin, John, Redman, James Edward ORCID: https://orcid.org/0000-0001-5492-2869, Altaher, Abdalsamed, Neville, Rachel Dawn, Webber, Jason P. ORCID: https://orcid.org/0000-0003-4772-3014, Kim, Min-Young and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2011. The human hyaluronan synthase 2 (HAS2) gene and its natural antisense RNA exhibit coordinated expression in the renal proximal tubular epithelial cell. Journal of Biological Chemistry 286 (22) , pp. 19523-19532. 10.1074/jbc.M111.233916

Martin, John, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Bennagi, Rasha, Krupa, Aleksandra, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 2011. Post-transcriptional regulation of transforming growth factor beta-1 by microrna-744. PLoS ONE 6 (10) , e25044. 10.1371/journal.pone.0025044
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Khammas, Hassan, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Williams, John David, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 and Martin, John 2011. Characterisation of the human ADAM15 promoter. Nephron Experimental Nephrology 118 (2) , e27-e38. 10.1159/000320698

Simpson, Russell M. L., Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2009. Age-related changes in pericellular hyaluronan organization leads to impaired dermal fibroblast to myofibroblast differentiation. American Journal of Pathology 175 (5) , pp. 1915-1928. 10.2353/ajpath.2009.090045

Zhang, Lei ORCID: https://orcid.org/0000-0003-3536-8692, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Grennan-Jones, Fiona Antoinette, Paddon, Carol Ann, Giles, Peter James ORCID: https://orcid.org/0000-0003-3143-6854, Webber, Jason P. ORCID: https://orcid.org/0000-0003-4772-3014, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 and Ludgate, Marian Elizabeth 2009. Thyrotropin receptor activation increases hyaluronan production in preadipocyte fibroblasts: Contributory role in hyaluronan accumulation in thyroid dysfunction. Journal of Biological Chemistry 284 (39) , pp. 26447-26455. 10.1074/jbc.M109.003616

Nair, S., Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Norton, Nadine ORCID: https://orcid.org/0000-0002-3848-4288, Spurlock, Gillian, Williams, Hywel John ORCID: https://orcid.org/0000-0001-7758-0312, Craig, Kathrine Jane, Williams, John David, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2008. Further evidence for the association of MMP9 with nephropathy in type 2 diabetes and application of DNA pooling technology to candidate gene screening. Journal of Nephology 21 (3) , pp. 400-405.

Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820, Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996, Martin, John, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 2007. Involvement of hyaluronan in regulation of fibroblast phenotype. The Journal of Biological Chemistry 282 (35) , pp. 25687-25697. 10.1074/jbc.M700773200

Saavalainen, Katri, Tammi, Markku I., Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Schmitz, M. Lienhard and Carlberg, Carsten 2007. Integration of the activation of the human hyaluronan synthase 2 gene promoter by common cofactors of the transcription factors retinoic acid receptor and nuclear factor kappaB. Journal of Biological Chemistry 282 (15) , pp. 11530-11539. 10.1074/jbc.M607871200

Martin, John, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496 2006. The pluripotent cytokine pleiotrophin is induced by wounding in human mesangial cells. Kidney International 70 (9) , pp. 1616-1622. 10.1038/sj.ki.5001800

Rashid Selbi, Wisam, de la Motte, C. A., Hascall, V. C., Day, A. J., Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 2006. Characterization of hyaluronan cable structure and function in renal proximal tubular epithelial cells. Kidney International 70 (7) , pp. 1287-1295. 10.1038/sj.ki.5001760

Monslow, Jamie, Williams, John David, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Michael, Daryn Robert, Foka, Pelagia, Kift-Morgan, Ann Patricia, Luo, Dong Dong, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Craig, Kathrine Jane, Topley, Nicholas, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2006. Sp1 and Sp3 mediate constitutive transcription of the human hyaluronan synthase 2 gene. The Journal of Biological Chemistry 281 (26) , pp. 18043-18050. 10.1074/jbc.M510467200

Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Fulop, C., Rugg, M. S. and Selbi, W. 2006. Overexpression of hyaluronan synthase 2 alters hyaluronan distribution and function in proximal tubular epithelial cells. Journal of the American Society of Nephrology 17 (6) , pp. 1553-67. 10.1681/ASN.2005080879

Topley, Nicholas, Michael, Daryn Robert and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2005. CA125: holy grail or a poisoned chalice. Nephron Clinical Practice 100 (2) , c52-c54. 10.1159/000085033

Monslow, Jamie, Williams, John David, Guy, Carol, Price, Iain Kelsey, Craig, Kathrine Jane, Williams, Hywel John ORCID: https://orcid.org/0000-0001-7758-0312, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Martin, John, Coleman, Sharon Louise, Topley, Nicholas, Spicer, Andrew P., Buckland, Paul Robert, Davies, Malcolm and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2004. Identification and analysis of the promoter region of the human hyaluronan synthase 2 gene. The Journal of Biological Chemistry 279 (20) , pp. 20576-20581. 10.1074/jbc.M312666200

Hoogendoorn, Bastiaan ORCID: https://orcid.org/0000-0001-9753-169X, Coleman, Sharon Louise, Guy, Carol, Smith, Susan Kaye, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Buckland, Paul Robert and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 2003. Functional analysis of human promoter polymorphisms. Human Molecular Genetics 12 (18) , pp. 2249-2254. 10.1093/hmg/ddg246

Monslow, Jamie, Williams, John David, Norton, Nadine ORCID: https://orcid.org/0000-0002-3848-4288, Guy, Carol, Price, Iain Kelsey, Coleman, Sharon Louise, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Buckland, Paul Robert, Spicer, Andrew P., Topley, Nicholas, Davies, Malcolm and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2003. The human hyaluronan synthase genes: genomic structures, proximal promoters and polymorphic microsatellite markers. The International Journal of Biochemistry & Cell Biology 35 (8) , pp. 1272-1283. 10.1016/S1357-2725(03)00048-7

Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Spurlock, Gillian, Norton, Nadine ORCID: https://orcid.org/0000-0002-3848-4288, Williams, Hywel John ORCID: https://orcid.org/0000-0001-7758-0312, Hoogendoorn, Bastiaan ORCID: https://orcid.org/0000-0001-9753-169X, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 2002. Determination of the genomic structure and mutation screening in schizophrenic individuals for five subunits of the N-methyl-D-aspartate glutamate receptor. Molecular Psychiatry 7 (5) , pp. 508-514. 10.1038/sj.mp.4001030

Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Norton, Nadine ORCID: https://orcid.org/0000-0002-3848-4288, Spurlock, G., Wittekindt, O. H., Morris-Rosendahl, D. J., Williams, Hywel John ORCID: https://orcid.org/0000-0001-7758-0312, Brzustowicz, L., Hoogendoorn, Bastiaan ORCID: https://orcid.org/0000-0001-9753-169X, Zammit, Stanley ORCID: https://orcid.org/0000-0002-2647-9211, Jones, G, Sanders, Rebecca, Jones, L. A., McCarthy, G., Jones, S., Bassett, A., Cardno, A. G., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 2001. Mutation screening of the KCNN3 gene reveals a rare frameshift mutation [Letter]. Molecular Psychiatry 6 (3) , pp. 259-260. 10.1038/sj.mp.4000128

Vincent, John B., Qiu-Ping, Yuan, Schalling, Martin, Adolfsson, R., Azevedo, M. Helena, Macedo, Antonio, Bauer, Amy, Dalla Torre, Camille, Medeiros, Helena M., Pato, Carlos N., Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Guy, Carol, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Paterson, Andrew D., Petronis, Arturas and Kennedy, James L. 2000. Long repeat tracts at SCA8 in major psychosis. American Journal of Medical Genetics 96 (6) , pp. 873-876. 10.1002/1096-8628(20001204)96:6<873::AID-AJMG37>3.0.CO;2-9

Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Ashworth, Lindsay, Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950, Guy, Carol, Jones, Ian Richard ORCID: https://orcid.org/0000-0001-5821-5889, McCandless, Fiona, Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 2000. No evidence of association from transmission disequilibrium analysis of the hKCa3 gene in bipolar disorder. Bipolar Disorders 2 (4) , pp. 328-331. 10.1034/j.1399-5618.2000.020406.x

Bray, Nicholas John ORCID: https://orcid.org/0000-0002-4357-574X, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Cardno, A. G., Gray, M., Jones, L. A., Murphy, K. C., Sanders, R., Spurlock, G., O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 2000. No evidence for association between a non-synonymous polymorphism in the gene encoding human metabotropic glutamate receptor 7 and schizophrenia. Psychiatric Genetics 10 (2) , pp. 83-86. 10.1097/00041444-200010020-00005

Austin, J., Hoogendoorn, Bastiaan ORCID: https://orcid.org/0000-0001-9753-169X, Buckland, Paul Robert, Speight, G., Cardno, A., Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Spurlock, G., Sanders, R., Jones, L., Murphy, Kevin, McCarthy, G., McGuffin, P., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 2000. Comparative sequencing of the proneurotensin gene and association studies in schizophrenia. Molecular Psychiatry 5 (2) , pp. 208-212. 10.1038/sj.mp.4000693

Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Guy, Carol, Cardno, A. G., Vincent, J. B., Kennedy, J. L., Jones, L. A., Gray, M, Sanders, Rhys, McCarthy, G, Murphy, K. C., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 2000. Repeat sizes at CAG/CTG loci CTG18.1, ERDA1 and TGC13-7a in schizophrenia. Psychiatric Genetics 10 (1) , pp. 33-37. 10.1097/00041444-200010010-00006

Williams, N.M. ORCID: https://orcid.org/0000-0001-7758-0312, Bowen, T. ORCID: https://orcid.org/0000-0001-6050-0435, Spurlock, G., Williams, H. ORCID: https://orcid.org/0000-0001-7758-0312, Norton, N., Austin, J., Walters, A., Owen, M.J. ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, M.C. ORCID: https://orcid.org/0000-0001-7073-2379 2000. Identification and characterisation of SNPs in candidate genes for schizophrenia. American Journal of Medical Genetics - Neuropsychiatric Genetics 96 (4) , p. 462.

Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950, Gill, M., Spurlock, Gillian, Vallada, H. P., Murray, R. M., McGuffin, P., Collier, D. A., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610 1999. Linkage studies of bipolar disorder with chromosome 18 markers. American Journal of Medical Genetics 15 (88) , pp. 503-509. 10.1002/(SICI)1096-8628(19991015)88:5<503::AID-AJMG13>3.0.CO;2-U

Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950, Williams, H., Hoogendorn, B., Asherson, P. and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 1999. Polymorphism screening and association studies of the Wolfram syndrome gene in schizophrenia. Molecular Psychiatry 4 (supp1) , S42-S42.

Guy, Carol, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Jones, Ian Richard ORCID: https://orcid.org/0000-0001-5821-5889, McCandless, F., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 1999. CTG18.1 and ERDA-1 CAG/CTG repeat size in bipolar disorder. Neurobiology of Disease 6 (4) , pp. 302-307. 10.1006/nbdi.1999.0249

Cardno, Alastair G., Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Guy, Carol, Jones, Lisa A., McCarthy, Geraldine, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Murphy, Kieran C., Spurlock, Gillian, Gray, Marion, Sanders, Rebecca, Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610, McGuffin, Peter, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 1999. CAG repeat length in the hKCa3 gene and symptom dimensions in schizophrenia. Biological Psychiatry 45 (12) , pp. 1592-1596. 10.1016/s0006-3223(99)00033-5

Franks, Emily, Guy, Carol, Jacobsen, N., Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610 1999. Eleven trinucleotide repeat loci that map to chromosome 12 excluded from involvement in the pathogenesis of bipolar disorder. American Journal of Medical Genetics 88 (1) , pp. 67-70. 10.1002/(SICI)1096-8628(19990205)88:1<67::AID-AJMG12>3.0.CO;2-#

Guy, Carol, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Jones, I. R., McCandless, F, McGuffin, P, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 1999. No association between a polymorphic CAG repeat in the human potassium channel gene hKCa3 and bipolar disorder. American Journal of Medical Genetics 88 (1) , pp. 57-60. 10.1002/(sici)1096-8628(19990205)88:1%3C57::aid-ajmg10%3E3.0.co;2-6

Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Guy, Carol, Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610, Cardno, A. G., Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Spurlock, G., Murphy, K. C., Jones, L. A., Gray, M., Sanders, Rebecca, McCarthy, G, Chandy, K. G., Fantino, E, Kalman, K, Gutman, G. A., Gargus, J. J., Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, McGuffin, P., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 1998. Further support for an association between a polymorphic CAG repeat in the hKCa3 gene and schizophrenia. Molecular Psychiatry 3 (3) , pp. 266-269. 10.1038/sj.mp.4000400

Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Norton, N, Jacobsen, N. J., Guy, Carol, Daniels, J. K., Sanders, Rebecca, Cardno, A. G., Jones, L. A., Murphy, Kevin, McGuffin, P, Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 1998. Linked polymorphisms upstream of exons 1 and 2 of the human cholecystokinin gene are not associated with schizophrenia or bipolar disorder. Molecular Psychiatry 3 (1) , pp. 67-71. 10.1038/sj.mp.4000293

Cardno, A. G., McCandless, F., Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Guy, Carol, Jones, L. A., Murphy, Kevin, McGuffin, P., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 1998. Association between functional psychosis and expanded CAG/CTG repeats is not explained by health stratification [comparative study]. Psychiatric Genetics 8 (1) , pp. 29-32. 10.1097/00041444-199800810-00005

Guy, Carol, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Daniels, J. K., Speight, G., McKeon, P., Mynett-Johnson, L., Claffey, E., McGuffin, P., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Craddock, Nicholas ORCID: https://orcid.org/0000-0003-2171-0610 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 1997. Exclusion of expansion of 50 CAG/CTG trinucleotide repeats in bipolar disorder. American Journal of Psychiatry 154 (8) , pp. 1146-1147.

Speight, G., Guy, Carol, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Asherson, P., McGuffin, P., Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 1997. Exclusion of CAG/CTG trinucleotide repeat loci which map to chromosome 4 in bipolar disorder and schizophrenia. American Journal of Medical Genetics 74 (2) , pp. 204-206. 10.1002/(SICI)1096-8628(19970418)74:2<204::AID-AJMG19>3.0.CO;2-M

O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Guy, Carol, Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, McKeon, P., Macedo, A., Maier, W., Wildenauer, D., Aschauer, H. N., Sorbi, S., Feldman, E., Mynett-Johnson, L., Claffey, E., Nacmias, B., Valente, J., Dourado, A., Grassi, E., Lenzinger, E., Heiden, A. M., Moorhead, S., Harrison, D., Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, McGuffin, P. and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 1996. Confirmation of association between expanded CAG/CTG repeats and both schizophrenia and bipolar disorder. Psychological Medicine -London- 26 (6) , pp. 1145-1153. 10.1017/s0033291700035868

Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Guy, Carol, Speight, G., Jones, L., Cardno, A., Murphy, Kevin, McGuffin, P., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 1996. Expansion of 50 CAG/CTG repeats excluded in schizophrenia by application of a highly efficient approach using repeat expansion detection and a PCR screening set. American Journal of Human Genetics 59 (4) , pp. 912-917.

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