Heurich, Meike ORCID: https://orcid.org/0000-0003-0105-2702, Föcking, Melanie and Cotter, David 2024. Complement C4, C4A and C4a – what they do and how they differ. Brain, Behavior, & Immunity - Health 39 , 100809. 10.1016/j.bbih.2024.100809 |
Byrne, Jonah F., Healy, Colm, Föcking, Melanie, Heurich, Meike ORCID: https://orcid.org/0000-0003-0105-2702, Susai, Subash Raj, Mongan, David, Wynne, Kieran, Kodosaki, Eleftheria, Woods, Scott W., Cornblatt, Barbara A., Stone, William S., Mathalon, Daniel H., Bearden, Carrie E., Cadenhead, Kristin S., Addington, Jean, Walker, Elaine F., Cannon, Tyrone D., Cannon, Mary, Jeffries, Clark, Perkins, Diana and Cotter, David R. 2024. Plasma complement and coagulation proteins as prognostic factors of negative symptoms: An analysis of the NAPLS 2 and 3 studies. Brain, Behavior, and Immunity 119 , pp. 188-196. 10.1016/j.bbi.2024.03.049 |
Kodosaki, Eleftheria, Healy, Colm, Byrne, Jonah F., Foecking, Melanie, Cannon, Mary, Perkins, Diana O., Cotter, David and Heurich, Meike ORCID: https://orcid.org/0000-0003-0105-2702 2024. Sample processing time but not storage time affects complement activation markers C4a, C4d, C3a, C3d, Bb, C5a, and sC5b-9 levels in EDTA-plasma of individuals at clinical high-risk for psychosis. Biomarkers in Neuropsychiatry 10 , 100097. 10.1016/j.bionps.2024.100097 |
Byrne, Jonah F., Healy, Colm, Föcking, Melanie, Susai, Subash Raj, Mongan, David, Wynne, Kieran, Kodosaki, Eleftheria, Heurich-Sevcenco, Meike ORCID: https://orcid.org/0000-0003-0105-2702, de Haan, Lieuwe, Hickie, Ian B., Smesny, Stefan, Thompson, Andrew, Markulev, Connie, Young, Alison Ruth, Schäfer, Miriam R., Riecher-Rössler, Anita, Mossaheb, Nilufar, Berger, Gregor, Schlögelhofer, Monika, Nordentoft, Merete, Chen, Eric Y. H., Verma, Swapna, Nieman, Dorien H., Woods, Scott W., Cornblatt, Barbara A., Stone, William S., Mathalon, Daniel H., Bearden, Carrie E., Cadenhead, Kristin S., Addington, Jean, Walker, Elaine F., Cannon, Tyrone D., Cannon, Mary, McGorry, Pat, Amminger, Paul, Cagney, Gerard, Nelson, Barnaby, Jeffries, Clark, Perkins, Diana and Cotter, David R. 2024. Proteomic biomarkers for the prediction of transition to psychosis in individuals at clinical high risk: A multi-cohort model development study. Schizophrenia Bulletin 50 (3) , pp. 579-588. 10.1093/schbul/sbad184 |
Healy, Colm, Byrne, Jonah, Raj Suasi, Subash, Föcking, Melanie, Mongan, David, Kodosaki, Eleftheria, Heurich, Meike ORCID: https://orcid.org/0000-0003-0105-2702, Cagney, Gerard, Wynne, Kieran, Bearden, Carrie E., Woods, Scott W., Cornblatt, Barbara, Mathalon, Daniel, Stone, William, Cannon, Tyrone D., Addington, Jean, Cadenhead, Kristin S., Perkins, Diana, Jeffries, Clark and Cotter, David 2024. Differential expression of haptoglobin in individuals at clinical high risk of psychosis and its association with global functioning and clinical symptoms. Brain, Behavior, and Immunity 117 , pp. 175-180. 10.1016/j.bbi.2023.12.018 |
Heurich, Meike ORCID: https://orcid.org/0000-0003-0105-2702 and McCluskey, Geneviève 2023. Complement and coagulation crosstalk - Factor H in the spotlight. Immunobiology 228 (6) , 152707. 10.1016/j.imbio.2023.152707 |
Cropley, V.L., Kittel, M., Heurich-Sevcenco, M. ORCID: https://orcid.org/0000-0003-0105-2702, Föcking, M., Leweke, F.M. and Pantelis, C. 2023. Complement proteins are elevated in blood serum but not CSF in clinical high-risk and antipsychotic-naïve first-episode psychosis. Brain, Behavior, and Immunity 113 , pp. 136-144. 10.1016/j.bbi.2023.07.004 |
Susai, Subash Raj, Föcking, Melanie, Mongan, David, Heurich, Meike ORCID: https://orcid.org/0000-0003-0105-2702, Coutts, Fiona, Egerton, Alice, Whetton, Tony, Winter-van Rossum, Inge, Unwin, Richard D., Pollak, Thomas A., Weiser, Mark, Leboyer, Marion, Rujescu, Dan, Byrne, Jonah F., Gifford, George W., Dazzan, Paola, Koutsouleris, Nikolaos, Kahn, René S., Cotter, David R. and McGuire, Philip 2023. Association of complement and coagulation pathway proteins with treatment response in first-episode psychosis: a longitudinal analysis of the OPTiMiSE clinical trial. Schizophrenia Bulletin: The Journal of Psychoses and Related Disorders 49 (4) , pp. 893-902. 10.1093/schbul/sbac201 |
Susai, Subash Raj, Healy, Colm, Mongan, David, Heurich-Sevcenco, Meike ORCID: https://orcid.org/0000-0003-0105-2702, Byrne, Jonah F., Cannon, Mary, Cagney, Gerard, Wynne, Kieran, Markulev, Connie, Schäfer, Miriam R., Berger, Maximus, Mossaheb, Nilufar, Schlögelhofer, Monika, Smesny, Stefan, Hickie, Ian B., Berger, Gregor E., Chen, Eric Y. H., de Haan, Lieuwe, Nieman, Dorien H., Nordentoft, Merete, Riecher-Rössler, Anita, Verma, Swapna, Street, Rebekah, Thompson, Andrew, Yung, Alison Ruth, Nelson, Barnaby, McGorry, Patrick D., Föcking, Melanie, Amminger, G. Paul and Cotter, David 2022. Evidence that complement and coagulation proteins are mediating the clinical response to omega-3 fatty acids: A mass spectrometry-based investigation in subjects at clinical high-risk for psychosis. Translational Psychiatry 12 , 454. 10.1038/s41398-022-02217-0 |
Heurich, Meike ORCID: https://orcid.org/0000-0003-0105-2702, Föcking, Melanie, Mongan, David, Cagney, Gerard and Cotter, David R. 2022. Dysregulation of complement and coagulation pathways: emerging mechanisms in the development of psychosis. Molecular Psychiatry 27 , pp. 127-140. 10.1038/s41380-021-01197-9 |
Baker, Alexander T., Boyd, Ryan J., Sarkar, Daipayan, Teijeira Crespo, Alicia, Chan, Chun Kit, Bates, Emily, Waraich, Kasim, Vant, John, Wilson, Eric, Truong, Chloe D., Lipka-Lloyd, Magdalena, Fromme, Petra, Vermaas, Josh, Williams, Dewight, Machiesky, LeeAnn, Heurich, Meike ORCID: https://orcid.org/0000-0003-0105-2702, Nagalo, Bolni M., Coughlan, Lynda, Umlauf, Scott, Chiu, Po-Lin, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Cohen, Taylor S., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Singharoy, Abhishek and Borad, Mitesh J. 2021. ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome. Science Advances 7 (49) , eabl8213. 10.1126/sciadv.abl8213 |
Pathare, Navichandra, Szakmany, Tamas ORCID: https://orcid.org/0000-0003-3632-8844, Hall, Judith E. ORCID: https://orcid.org/0000-0002-6770-7372 and Heurich, Meike ORCID: https://orcid.org/0000-0003-0105-2702 2021. Plasma IgM levels differentiate between survivors and non-survivors of culture-positive and culture-negative sepsis and SIRS: a pilot study. Journal of Clinical Medicine 10 (22) , 5391. 10.3390/jcm10225391 |
Howes, Oliver, Cummings, Connor and Heurich, Meike ORCID: https://orcid.org/0000-0003-0105-2702 2021. Translation from genes to mechanism in schizophrenia: are immune-synaptic interactions the missing link? Biological Psychiatry 90 (9) , pp. 593-595. 10.1016/j.biopsych.2021.08.014 |
Flude, Ben M., Nannetti, Giulio ORCID: https://orcid.org/0000-0003-3227-1537, Mitchell, Paige, Compton, Nina, Richards, Chloe, Heurich, Meike ORCID: https://orcid.org/0000-0003-0105-2702, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Ferla, Salvatore ORCID: https://orcid.org/0000-0002-5918-9237 and Bassetto, Marcella ORCID: https://orcid.org/0000-0002-2491-5868 2021. Targeting the complement serine protease MASP-2 as a therapeutic strategy for coronavirus infections. Viruses 13 (2) , 312. 10.3390/v13020312 |
Mongan, David, Föcking, Melanie, Healy, Colm, Susai, Subash Raj, Heurich, Meike ORCID: https://orcid.org/0000-0003-0105-2702, Wynne, Kieran, Nelson, Barnaby, McGorry, Patrick D., Amminger, G. Paul, Nordentoft, Merete, Krebs, Marie-Odile, Riecher-Rössler, Anita, Bressan, Rodrigo A., Barrantes-Vidal, Neus, Borgwardt, Stefan, Ruhrmann, Stephan, Sachs, Gabriele, Pantelis, Christos, van der Gaag, Mark, de Haan, Lieuwe, Valmaggia, Lucia, Pollak, Thomas A., Kempton, Matthew J., Rutten, Bart P. F., Whelan, Robert, Cannon, Mary, Zammit, Stan ORCID: https://orcid.org/0000-0002-2647-9211, Cagney, Gerard, Cotter, David R. and McGuire, Philip 2021. Development of proteomic prediction models for transition to psychotic disorder in the clinical high-risk state and psychotic experiences in adolescence. JAMA Psychiatry 78 (1) , pp. 77-90. 10.1001/jamapsychiatry.2020.2459 |
Madrid-Gambin, Francisco, Föcking, Melanie, Sabherwal, Sophie, Heurich, Meike ORCID: https://orcid.org/0000-0003-0105-2702, English, Jane A., O'Gorman, Aoife, Suvitaival, Tommi, Ahonen, Linda, Cannon, Mary, Lewis, Glynn, Mattila, Ismo, Scaife, Caitriona, Madden, Sean, Hyötyläinen, Tuulia, Orešič, Matej, Zammit, Stanley ORCID: https://orcid.org/0000-0002-2647-9211, Cagney, Gerard, Cotter, David R. and Brennan, Lorraine 2019. Integrated lipidomics and proteomics point to early blood-based changes in childhood preceding later development of psychotic experiences: evidence from the Avon Longitudinal Study of Parents and Children. Biological Psychiatry 86 (1) , pp. 25-34. 10.1016/j.biopsych.2019.01.018 |
Föcking, Melanie, Sabherwal, Sophie, Cates, Hannah M., Scaife, Caitriona, Dicker, Patrick, Hryniewiecka, Magdalena, Wynne, Kieran, Rutten, Bart P. F., Lewis, Glyn, Cannon, Mary, Nestler, Eric J., Heurich-Sevcenco, Meike ORCID: https://orcid.org/0000-0003-0105-2702, Cagney, Gerard, Zammit, Stanley ORCID: https://orcid.org/0000-0002-2647-9211 and Cotter, David R. 2019. Complement pathway changes at age 12 are associated with psychotic experiences at age 18 in a longitudinal population-based study: evidence for a role of stress. Molecular Psychiatry 26 , pp. 524-533. 10.1038/s41380-018-0306-z |
Martínez-Barricarte, Rubén, Heurich-Sevcenco, Meike ORCID: https://orcid.org/0000-0003-0105-2702, López-Perrote, Andrés, Tortajada, Agustin, Pinto, Sheila, López-Trascasa, Margarita, Sánchez-Corral, Pilar, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676, Llorca, Oscar, Harris, Claire L. and Rodríguez de Córdoba, Santiago 2015. The molecular and structural bases for the association of complement C3 mutations with atypical hemolytic uremic syndrome. Molecular Immunology 66 (2) , pp. 263-273. 10.1016/j.molimm.2015.03.248 |
Szakmany, Tamas ORCID: https://orcid.org/0000-0003-3632-8844 and Heurich-Sevcenco, Meike ORCID: https://orcid.org/0000-0003-0105-2702 2015. Immunomodulation in sepsis - why blunting the response doesn't work? Journal of Infection 71 (2) , pp. 147-149. 10.1016/j.jinf.2015.04.019 |
Ruseva, M.M. and Heurich-Sevcenco, Meike ORCID: https://orcid.org/0000-0003-0105-2702 2014. Purification and characterization of human and mouse complement C3. Gadjeva, Mihaela, ed. The Complement System: Methods and Protocols, Vol. 1100. Methods in Molecular Biology, Humana Press, pp. 75-91. (10.1007/978-1-62703-724-2_6) |
Heurich, Meike ORCID: https://orcid.org/0000-0003-0105-2702, Altintas, Zeynep and Tothill, Ibtisam 2013. Computational Design of Peptide Ligands for Ochratoxin A. Toxins 5 (6) , pp. 1202-1218. 10.3390/toxins5061202 |
Harris, Claire Louise, Heurich, Meike ORCID: https://orcid.org/0000-0003-0105-2702, Rodriguez de Cordoba, Santiago and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2012. The complotype: dictating risk for inflammation and infection. Trends in Immunology 33 (10) , pp. 513-521. 10.1016/j.it.2012.06.001 |
Heurich, Meike ORCID: https://orcid.org/0000-0003-0105-2702, Martinez-Barricarte, Ruben, Francis, Nigel ORCID: https://orcid.org/0000-0002-4706-4795, Roberts, Dawn L., Rodriguez de Cordoba, Santiago, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Harris, Claire Louise 2011. Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk. Proceedings of the National Academy of Sciences of the United States of America 108 (21) , pp. 8761-8766. 10.1073/pnas.1019338108 |
Martínez-Barricarte, Rubén, Heurich, Meike ORCID: https://orcid.org/0000-0003-0105-2702, Valdes-Cañedo, Francisco, Vazquez-Martul, Eduardo, Torreira, Eva, Montes, Tamara, Tortajada, Agustín, Pinto, Sheila, Lopez-Trascasa, Margarita, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676, Llorca, Oscar, Harris, Claire Louise and Rodríguez de Córdoba, Santiago 2010. Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation. Journal of Clinical Investigation 120 (10) , pp. 3702-3712. 10.1172/JCI43343 |