Browse by Current Cardiff authors

Badder, Luned, Davies, James ORCID: https://orcid.org/0000-0003-3569-4500, Meniel, Valerie, Maruskova, Mahulena, Salvador, Beatriz, Bayliss, Rebecca ORCID: https://orcid.org/0000-0002-3324-957X, Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Hogan, Catherine ORCID: https://orcid.org/0000-0002-1012-0896 and Parker, Alan ORCID: https://orcid.org/0000-0002-9302-1761 2024. The αvβ6 integrin specific virotherapy, Ad5NULL-A20.FCU1, selectively delivers 2 potent “in-tumour” chemotherapy to Pancreatic Ductal Adenocarcinoma. British Journal of Cancer 131 , pp. 1694-1706. 10.1038/s41416-024-02869-3

Bliss, Carly M., Hulin-Curtis, Sarah L., Williams, Marta, Marusková, Mahulena, Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Statkute, Evelina, Baker, Alexander T. ORCID: https://orcid.org/0000-0001-8232-0531, Stack, Louise, Kerstetter, Lucas, Kerr-Jones, Lauren E., Milward, Kate, Russell, Gabrielle, George, Sarah J., Badder, Luned M., Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Coughlan, Lynda, Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2024. A pseudotyped adenovirus serotype 5 vector with serotype 49 fiber knob is an effective vector for vaccine and gene therapy applications. Molecular Therapy - Methods and Clinical Development 32 (3) , 101308. 10.1016/j.omtm.2024.101308

Wallace, Rebecca, Bliss, Carly M. and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2024. The immune system - A double-edged sword for adenovirus-based therapies. Viruses 16 (6) , 973. 10.3390/v16060973

Gardner, Joshua, Abrams, Simon Timothy, Toh, Cheng-Hock, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Lovatt, Charlotte, Nicolson, Phillip L. R., Watson, Steve P., Grice, Sophie, Hering, Luisa, Pirmohamed, Munir and Naisbitt, Dean J. 2024. Identification of cross reactive T cell responses in adenovirus based COVID 19 vaccines. npj Vaccines 9 (1) , 99. 10.1038/s41541-024-00895-z

Mundy, Rosie M., Baker, Alexander T. ORCID: https://orcid.org/0000-0001-8232-0531, Bates, Emily A., Cunliffe, Tabitha G., Teijeira Crespo, Alicia, Moses, Elise, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2023. Broad sialic acid usage amongst species D human adenovirus. npj Viruses 1 , 1. 10.1038/s44298-023-00001-5

Preston, Hannah E., Bayliss, Rebecca ORCID: https://orcid.org/0000-0002-3324-957X, Temperton, Nigel, Neto, Martin Mayora, Brewer, Jason and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2023. Capture and inactivation of viral particles from bioaerosols by electrostatic precipitation. iScience 26 (9) , 107567. 10.1016/j.isci.2023.107567

Lovatt, Charlotte and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2023. Oncolytic viruses and immune checkpoint inhibitors: the "hot" new power couple. Cancers 15 (16) , 4178. 10.3390/cancers15164178

Bates, Emily A., Lovatt, Charlotte, Plein, Alice R., Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2023. Engineering adenoviral vectors with improved GBM selectivity. Viruses 15 (5) , 1086. 10.3390/v15051086

Othman, Maha, Baker, Alexander T. ORCID: https://orcid.org/0000-0001-8232-0531, Gupalo, Elena, Elsebaie, Abdelrahman, Bliss, Carly M., Rondina, Matthew T., Lillicrap, David and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2023. Corrigendum to To clot or not to clot? Ad is the question?Insights on mechanisms related to vaccine-induced thrombotic thrombocytopenia [J Thromb Haemost. 2021 Nov;19(11):2845-2856. doi: 10.1111/jth.15485]. Journal of Thrombosis and Haemostasis 10.1016/j.jtha.2023.01.022

Swift, Emma A., Pollard, Steven M. and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2022. Engineering cancer selective virotherapies: are the pieces of the puzzle falling into place? Human Gene Therapy 33 (21-22) 10.1089/hum.2022.178

Cunliffe, Tabitha G., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 and Jaramillo, Alfonso 2022. Pseudotyping bacteriophage P2 tail fibers to extend the host range for biomedical applications. ACS Synthetic Biology 11 (10) , pp. 3207-3215. 10.1021/acssynbio.1c00629

Bates, Emily A., Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Vánová, Jana, Nestic, Davor, Meniel, Valerie S., Koushyar, Sarah, Cunliffe, Tabitha G., Mundy, Rosie M., Moses, Elise, Uusi-Kerttula, Hanni K., Baker, Alexander T. ORCID: https://orcid.org/0000-0001-8232-0531, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Majhen, Dragomira, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Chester, John D. ORCID: https://orcid.org/0000-0002-7830-3840 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2022. Development of a low seroprevalence, αvβ6 integrin selective virotherapy based on human adenovirus type 10. Molecular Therapy - Oncolytics 25 , pp. 43-56. 10.1016/j.omto.2022.03.007

Toh, Cheng-Hock, Wang, Guozheng and Parker, Alan L ORCID: https://orcid.org/0000-0002-9302-1761 2022. The aetiopathogenesis of vaccine-induced immune thrombotic thrombocytopenia. Clinical Medicine 22 (2) , pp. 140-144. 10.7861/clinmed.2022-0006

Tate, Sophia J., Van de Sande, Leen, Ceelen, Wim P., Torkington, Jared and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2021. The feasibility of Pressurised Intraperitoneal Aerosolised Virotherapy (PIPAV) to administer oncolytic adenoviruses. Pharmaceutics 13 (12) , 2043. 10.3390/pharmaceutics13122043

Baker, Alexander T., Boyd, Ryan J., Sarkar, Daipayan, Teijeira Crespo, Alicia, Chan, Chun Kit, Bates, Emily, Waraich, Kasim, Vant, John, Wilson, Eric, Truong, Chloe D., Lipka-Lloyd, Magdalena, Fromme, Petra, Vermaas, Josh, Williams, Dewight, Machiesky, LeeAnn, Heurich, Meike ORCID: https://orcid.org/0000-0003-0105-2702, Nagalo, Bolni M., Coughlan, Lynda, Umlauf, Scott, Chiu, Po-Lin, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Cohen, Taylor S., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Singharoy, Abhishek and Borad, Mitesh J. 2021. ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome. Science Advances 7 (49) , eabl8213. 10.1126/sciadv.abl8213

Othman, Maha, Baker, Alexander T. ORCID: https://orcid.org/0000-0001-8232-0531, Gupalo, Elena, Elsebaie, Abdelrahman, Bliss, Carly M., Rondina, Matthew T., Lillicrap, David and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2021. To clot or not to clot? Ad is the question - insights on mechanisms related to vaccine induced thrombotic thrombocytopenia. Journal of Thrombosis and Haemostasis 19 (11) , pp. 2845-2856. 10.1111/jth.15485

Nestic, Davor, Bozinovic, Ksenija, Pehar, Isabela, Wallace, Rebecca, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 and Majhen, Dragomira 2021. The revolving door of adenovirus cell entry: not all pathways are equal. Pharmaceutics 13 (10) , 1585. 10.3390/pharmaceutics13101585

Teijeira Crespo, Alicia, Burnell, Stephanie, Capitani, Lorenzo, Bayliss, Rebecca ORCID: https://orcid.org/0000-0002-3324-957X, Moses, Elise, Mason, Georgina H., Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Godkin, Andrew J. ORCID: https://orcid.org/0000-0002-1910-7567, Gallimore, Awen M. ORCID: https://orcid.org/0000-0001-6675-7004 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2021. Pouring petrol on the flames: using oncolytic virotherapies to enhance tumour immunogenicity. Immunology 163 (4) , pp. 389-398. 10.1111/imm.13323

Bates, Emily A., Counsell, John R., Alizert, Sophie, Baker, Alexander T. ORCID: https://orcid.org/0000-0001-8232-0531, Suff, Natalie, Boyle, Ashley, Bradshaw, Angela C., Waddington, Simon N., Nicklin, Stuart A., Baker, Andrew H. ORCID: https://orcid.org/0000-0001-8232-0531 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2021. In vitro and in vivo evaluation of human adenovirus type 49 as a vector for therapeutic applications. Viruses 13 (8) , 1483. 10.3390/v13081483

Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Marlow, Gareth ORCID: https://orcid.org/0000-0002-7608-9086, Uusi-Kerttula, Hanni K., Seaton, Gillian, Piggott, Luke, Badder, Luned M., Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Chester, John D. ORCID: https://orcid.org/0000-0002-7830-3840 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2021. Efficient intravenous tumor targeting using the αvβ6 integrin-selective precision virotherapy Ad5NULL-A20. Viruses 13 (5) , 864. 10.3390/v13050864

Baker, Alexander T. ORCID: https://orcid.org/0000-0001-8232-0531, Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Bates, Emily A., Moses, Elise, Mundy, Rosie M., Marlow, Gareth ORCID: https://orcid.org/0000-0002-7608-9086, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Bliss, Carly M., Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2021. The fiber knob protein of human adenovirus type 49 mediates highly efficient and promiscuous infection of cancer cell lines using a novel cell entry mechanism. Journal of Virology 95 (4) , e01849-20. 10.1128/JVI.01849-20

Wongthida, Phonphimon, Schuelke, Matthew R., Driscoll, Christopher B., Kottke, Timothy, Thompson, Jill M, Tonne, Jason, Stone, Cathy, Huff, Amanda L., Wetmore, Cynthia, Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Evgin, Laura and Vile, Richard G. 2020. Ad-CD40L mobilizes CD4 T cells for the treatment of brainstem tumors. Neuro-Oncology 22 (12) , pp. 1757-1770. 10.1093/neuonc/noaa126

Hulin-Curtis, Sarah ORCID: https://orcid.org/0000-0003-0889-964X, Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Nestic, Davor, Bates, Emily A., Baker, Alexander T. ORCID: https://orcid.org/0000-0001-8232-0531, Cunliffe, Tabitha G., Majhen, Dragomira, Chester, John D. ORCID: https://orcid.org/0000-0002-7830-3840 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2020. Identification of folate receptor α (FRα) binding oligopeptides and their evaluation for targeted virotherapy applications. Cancer Gene Therapy 27 , pp. 785-798. 10.1038/s41417-019-0156-0

Cunliffe, Tabitha G., Bates, Emily A. and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2020. Hitting the target but missing the point: recent progress towards adenovirus-based precision virotherapies. Cancers 12 (11) , 3327. 10.3390/cancers12113327

Mowbray, N. G., Ansell, J., Horwood, J., Cornish, J., Rizkallah, P. ORCID: https://orcid.org/0000-0002-9290-0369, Parker, A. ORCID: https://orcid.org/0000-0002-9302-1761, Wall, P., Spinelli, A. and Torkington, J. 2020. Safe management of surgical smoke in the age of COVID-19. British Journal of Surgery 107 (11) , pp. 1406-1413. 10.1002/bjs.11679

Scurr, Martin J. ORCID: https://orcid.org/0000-0002-4120-0688, Greenshields-Watson, Alexander, Campbell, Emma, Somerville, Michelle, Chen, Yuan, Hulin-Curtis, Sarah L. ORCID: https://orcid.org/0000-0003-0889-964X, Burnell, Stephanie E. A., Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Davies, Michael M. ORCID: https://orcid.org/0000-0003-3569-4500, Hargest, Rachel ORCID: https://orcid.org/0000-0001-9830-3832, Phillips, Simon, Christian, Adam D., Ashelford, Kevin E. ORCID: https://orcid.org/0000-0003-3217-2811, Andrews, Robert, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2020. Cancer antigen discovery is enabled by RNA-sequencing of highly purified malignant and non-malignant cells. Clinical Cancer Research 10.1158/1078-0432.CCR-19-3087

Crowther, Michael D., Dolton, Garry, Legut, Mateusz, Caillaud, Marine E., Lloyd, Angharad, Attaf, Meriem, Galloway, Sarah A. E., Rius, Cristina, Farrell, Colin P., Szomolay, Barbara ORCID: https://orcid.org/0000-0002-5375-5533, Ager, Ann ORCID: https://orcid.org/0000-0002-5763-8908, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Fuller, Anna, Donia, Marco, McCluskey, James, Rossjohn, Jamie ORCID: https://orcid.org/0000-0002-2020-7522, Svane, Inge Marie, Phillips, John D. and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2020. Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1. Nature Immunology 21 , 178 - 185. 10.1038/s41590-019-0578-8

Man, Stella, Foster, Julie, Carapuca, Elisabete, Davies, James A ORCID: https://orcid.org/0000-0003-3569-4500, Parker, Alan ORCID: https://orcid.org/0000-0002-9302-1761, Sosabowski, Jane and Hallden, Gunnel 2019. Systemic delivery and SPECT/CT in vivo imaging of 125I-labelled oncolytic adenoviral mutants in models of pancreatic cancer. Scientific Reports 9 , 12840. 10.1038/s41598-019-49150-9

Baker, Alexander ORCID: https://orcid.org/0000-0001-8232-0531, Mundy, Rosie M., Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Rizkallah, Pierre and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2019. Human adenovirus type 26 uses sialic acid - bearing glycans as a primary cell entry receptor. Science Advances 5 (9) , eaax3567. 10.1126/sciadv.aax3567

Baker, Alexander T. ORCID: https://orcid.org/0000-0001-8232-0531, Mundy, Rosie, Davies, James ORCID: https://orcid.org/0000-0003-3569-4500, Rizkillah, Pierre T. and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2019. Adenovirus serotype 26 utilises sialic acid bearing glycans as a primary cell entry receptor. [Online]. bioRxiv. Available at: https://doi.org/10.1101/580076

Baker, Alexander T. ORCID: https://orcid.org/0000-0001-8232-0531, Greenshields-Watson, Alexander, Coughlan, Lynda, Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Uusi-Kerttula, Hanni, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2019. Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactions. Nature Communications 10 , 741. 10.1038/s41467-019-08599-y

Uusi-Kerttula, Hanni, Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Thompson, Jill M., Wongthida, Phonphimon, Evgin, Laura, Shim, Kevin G., Bradshaw, Angela, Baker, Alexander T. ORCID: https://orcid.org/0000-0001-8232-0531, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Jones, Rachel, Hanna, Louise, Hudson, Emma, Vile, Richard, Chester, John D. ORCID: https://orcid.org/0000-0002-7830-3840 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2018. Ad5NULL-A20 - a tropism-modified, αvβ6 integrin-selective oncolytic adenovirus for epithelial ovarian cancer therapies. Clinical Cancer Research 24 (17) , pp. 4215-4224. 10.1158/1078-0432.CCR-18-1089

Baker, Alexander ORCID: https://orcid.org/0000-0001-8232-0531, Aguirre-Hernández, Carmen, Halldén, Gunnel and Parker, Alan ORCID: https://orcid.org/0000-0002-9302-1761 2018. Designer oncolytic adenovirus: coming of age. Cancers 10 (6) , 201. 10.3390/cancers10060201

Hulin-Curtis, Sarah ORCID: https://orcid.org/0000-0003-0889-964X, Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Jones, Rachel, Hudson, Emma, Hanna, Louise, Chester, John D. ORCID: https://orcid.org/0000-0002-7830-3840 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2018. Histone deacetylase inhibitor trichostatin A sensitises cisplatin-resistant ovarian cancer cells to oncolytic adenovirus. Oncotarget 9 (41) , pp. 26328-26341. 10.18632/oncotarget.25242

Man, Y. K. Stella, Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Coughlan, Lynda, Pantelidou, Constantia, Blázquez-Moreno, Alfonso, Marshall, John F., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 and Halldén, Gunnel 2018. The novel oncolytic adenoviral mutant Ad5-3Δ-A20T retargeted to αvβ6 integrins efficiently eliminates pancreatic cancer cells. Molecular Cancer Therapeutics 17 (2) , pp. 575-587. 10.1158/1535-7163.MCT-17-0671

Uusi-Kerttula, Hanni and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2018. Precision virotherapies: Coming soon. Oncotarget 9 (86) 10.18632/oncotarget.26280

Yan, Bing, Wang, Zengbo, Parker, Alan ORCID: https://orcid.org/0000-0002-9302-1761, Lai, Yukun ORCID: https://orcid.org/0000-0002-2094-5680, Thomas, John P., Yue, Liyang and Monks, James N. 2017. Superlensing microscope objective lens. Applied Optics 56 (11) , pp. 3142-3147. 10.1364/AO.56.003142

Robertson, Stacy, Alba, Raul, Duffy, Margeret R., Clarke, Carolyn, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Nicklin, Stuart A. and Baker, Andrew H. 2016. Retargeting FX binding-ablated HAdV-5 to vascular cells by inclusion of the RGD-4C peptide in hexon hypervariable region 7 and the HI loop. Journal of General Virology 97 (8) , pp. 1911-1916. 10.1099/jgv.0.000505

Hulin-Curtis, Sarah ORCID: https://orcid.org/0000-0003-0889-964X, Uusi-Kerttula, Hanni, Jones, R., Hanna, L., Chester, John D. ORCID: https://orcid.org/0000-0002-7830-3840 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2016. Evaluation of CD46 re-targeted adenoviral vectors for clinical ovarian cancer intraperitoneal therapy. Cancer Gene Therapy 23 (7) , pp. 229-234. 10.1038/cgt.2016.22

Uusi-Kerttula, Hanni, Davies, James ORCID: https://orcid.org/0000-0003-3569-4500, Curtis, Sarah ORCID: https://orcid.org/0000-0003-0889-964X, Chester, John ORCID: https://orcid.org/0000-0002-7830-3840 and Parker, Alan ORCID: https://orcid.org/0000-0002-9302-1761 2016. Pseudotyped αvβ6 integrin-targeted adenovirus vectors for ovarian cancer therapies. Oncotarget 7 (19) , pp. 27926-27937. 10.18632/oncotarget.8545

Uusi-Kerttula, Hanni, Hulin-Curtis, Sarah ORCID: https://orcid.org/0000-0003-0889-964X, Davies, James Anthony ORCID: https://orcid.org/0000-0003-3569-4500 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2015. Oncolytic adenovirus: strategies and insights for vector design and immuno-oncolytic applications. Viruses 7 (11) , pp. 6009-6042. 10.3390/v7112923

Uusi-Kerttula, Hanni, Davies, J. A., Coughlan, L., Chester, J. D., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 and Parker, A. L. 2015. Incorporation of avß6 integrin-targeting peptide into chimaeric Ad5/fibre knob 48 vector results in efficient tumour-targeting and evasion of neutralisation in clinical ascites. Human Gene Therapy 26 (10) , A93-A93. 10.1089/hum.2015.29008.abstracts

Uusi-Kerttula, Hanni, Davies, James, Coughlan, Lynda, Jones, Rachel, Chester, John D. ORCID: https://orcid.org/0000-0002-7830-3840 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2015. Development of an Ad5 vector pseudotyped with Ad48 knob protein and targeted to αvβ6 integrin efficiently targets tumour cells and evades pre-existing immunity in clinical ascites. Human Gene Therapy 26 (9) , A33-A33. 10.1089/hum.2015.29005.abstracts

Uusi-Kerttula, Hanni, Legut, Mateusz, Davies, James, Jones, Rachel, Hudson, Emma, Hanna, Louise, Stanton, Richard J., Chester, John D. ORCID: https://orcid.org/0000-0002-7830-3840 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2015. Modulation of Ad5 fibre knob as a means of circumventing pre-existing immunity in clinical ovarian ascites. Human Gene Therapy 26 (9) , A23-A23. 10.1089/hum.2015.29005.abstracts

Hulin-Curtis, Sarah ORCID: https://orcid.org/0000-0003-0889-964X, Uusi-Kerttula, Hanni, Jones, Rachel, Baker, Andrew, Chester, John D. ORCID: https://orcid.org/0000-0002-7830-3840 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2015. Evaluation of CD46 utilising adenoviral vectors for clinical ovarian cancer applications [Abstract]. Human Gene Therapy 26 (9) , A33-A34. 10.1089/hum.2015.29005.abstracts

Uusi-Kerttula, Hanni, Legut, Mateusz, Davies, James Anthony ORCID: https://orcid.org/0000-0003-3569-4500, Jones, Rachel, Hudson, Emma, Hanna, Louise, Stanton, Richard James ORCID: https://orcid.org/0000-0002-6799-1182, Chester, John D. ORCID: https://orcid.org/0000-0002-7830-3840 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2015. Incorporation of peptides targeting EGFR and FGFR1 into the adenoviral fibre knob domain, and their evaluation as targeted cancer therapies. Human Gene Therapy 26 (5) , pp. 320-329. 10.1089/hum.2015.015

Dakin, Rachel S., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Delles, Christian, Nicklin, Stuart A. and Baker, Andrew H. 2015. Efficient transduction of primary vascular cells by the rare adenovirus serotype 49 vector. Human Gene Therapy 26 (5) , pp. 312-319. 10.1089/hum.2015.019

Nivsarkar, Megha S., Buckley, Suzanne M. K., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Perocheau, Dany, McKay, Tristan R., Rahim, Ahad A., Howe, Steven J. and Waddington, Simon N. 2015. Evidence for contribution of CD4+CD25+ regulatory T cells in maintaining immune tolerance to human factor IX following perinatal adenovirus vector delivery. Journal of Immunology Research 2015 , 397879. 10.1155/2015/397879

Guinn, Barbara-ann, Braidwood, Lynne, Parker, Alan ORCID: https://orcid.org/0000-0002-9302-1761, Peng, Kah-Whye and Seymour, Leonard 2014. 8th international conference on oncolytic virus therapeutics. Human Gene Therapy 25 (12) , pp. 1062-1084. 10.1089/hum.2014.118

Dakin, R. S., Parker, Alan ORCID: https://orcid.org/0000-0002-9302-1761, Ma, J., Custers, J., Nicklin, S. A. and Baker, A. H. 2014. Efficient gene transfer to human vascular cells in vitro and ex vivo using adenovirus serotype 49. Cardiovascular Research 103 (suppl) , S42. 10.1093/cvr/cvu082.170

Coughlan, Lynda, Uusi-Kerttula, Hanni, Ma, Jiangtao, Degg, Bethany P., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 and Baker, Andrew H. 2014. Retargeting adenovirus serotype 48 fiber knob domain by peptide incorporation. Human Gene Therapy 25 (4) , pp. 385-394. 10.1089/hum.2014.016

Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Bradshaw, Angela C., Alba, Raul, Nicklin, Stuart A. and Baker, Andrew H. 2013. Capsid modification strategies for detargeting adenoviral vectors. Chillon, Miguel and Bosch, Assumpcio, eds. Adenovirus, Vol. 1089. Methods in Molecular Biology, Humana Press, pp. 45-59. (10.1007/978-1-62703-679-5_3)

Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, White, K M, Lavery, C A, Custers, J, Waddington, S N and Baker, A H 2013. Pseudotyping the adenovirus serotype 5 capsid with both the fibre and penton of serotype 35 enhances vascular smooth muscle cell transduction. Gene Therapy 20 (12) , pp. 1158-1164. 10.1038/gt.2013.44

White, Katie M, Alba, Raul, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Wright, Audrey F, Bradshaw, Angela C, Delles, Christian, McDonald, Robert A and Baker, Andrew H 2013. Assessment of a novel, capsid-modified adenovirus with an improved vascular gene transfer profile. Journal of Cardiothoracic Surgery 8 (1) , 183. 10.1186/1749-8090-8-183

Kaur, H., Toukh, M., Corscadden, K., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 and Othman, M. 2013. Fucoidan improves adenovirus mediated thrombocytopenia and enhances viral liver transduction [Abstract]. Journal of Thrombosis and Haemostatis 11 (S1) , pp. 451-452. 10.1111/jth.12284

Duffy, Margaret R., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Kalkman, Eric R., White, Katie, Kovalskyy, Dmytro, Kelly, Sharon M. and Baker, Andrew H. 2013. Identification of novel small molecule inhibitors of adenovirus gene transfer using a high throughput screening approach. Journal of Controlled Release 170 (1) , pp. 132-140. 10.1016/j.jconrel.2013.05.007

Coughlan, Lynda, Bradshaw, Angela C., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Robinson, Hollie, White, Katie, Custers, Jerome, Goudsmit, Jaap, Van Roijen, Nico, Barouch, Dan H., Nicklin, Stuart A. and Baker, Andrew H. 2012. Ad5:Ad48 hexon hypervariable region substitutions lead to toxicity and increased inflammatory responses following intravenous delivery. Molecular Therapy 20 (12) , pp. 2268-2281. 10.1038/mt.2012.162

Duffy, Margaret R., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Bradshaw, Angela C. and Baker, Andrew H. 2012. Manipulation of adenovirus interactions with host factors for gene therapy applications. Nanomedicine 7 (2) , pp. 271-288. 10.2217/nnm.11.186

Coughlan, Lynda, Uusi-Kerttula, Hanni, Degg, B., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Custers, Jerome, Nicklin, Stuart A. and Baker, Andrew H. 2011. In vitro assessment of targeting peptide incorporation within the knob domain of human adenovirus type 48 fiber. Human Gene Therapy 22 (10) , A128-A128.

Duffy, Margaret R., Bradshaw, Angela C., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, McVey, John H. and Baker, Andrew H. 2011. A Cluster of Basic Amino Acids in the Factor X Serine Protease Mediates Surface Attachment of Adenovirus/FX Complexes. Journal of Virology 85 (20) , pp. 10914-10919. 10.1128/JVI.05382-11

Duffy, M. R., Bradshaw, A. C., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, McVey, J. H. and Baker, A. H. 2011. A cluster of basic amino acids in the factor X serine protease mediate surface attachment of adenovirus:FX complexes [Abstract]. Human Gene Therapy 22 (10) , A34-A34. 10.1089/hum.2011.2525

Kitahara, Hiroe, Masumoto, Junya, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Maruta, Fukuto, Kubo, Naoki, Shimizu, Akira, Akita, Noriyuko, Miwa, Shiro, Kobayashi, Naoya, Nakayama, Jun and Miyagawa, Shinichi 2011. COP35, a cholangiocarcinoma-binding oligopeptide, interacts with the clathrin heavy chain accompanied by GRP78. Molecular Cancer Research 9 (6) , pp. 688-701. 10.1158/1541-7786.MCR-10-0470

Othman, Maha, Chirinian, Yvette, Brown, Christine, Notley, Colleen, Hickson, Nicholas, Hampshire, Daniel, Buckley, Suzanne, Waddington, Simon, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Baker, Andrew, James, Paula and Lillicrap, David 2010. Functional characterization of a 13-bp deletion (c.-1522_-1510del13) in the promoter of the von Willebrand factor gene in type 1 von Willebrand disease. Blood 116 (18) , pp. 3645-3652. 10.1182/blood-2009-12-261131

Alba, Raul, Bradshaw, Angela C., Coughlan, Lynda, Denby, Laura, McDonald, Robert A., Waddington, Simon N., Buckley, Suzanne M. K., Greig, Jenny A., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Miller, Ashley M., Wang, Hongjie, Lieber, Andre, van Rooijen, Nico, McVey, John H,, Nicklin, Stuart A. and Baker, Andrew H. 2010. Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors. Blood 116 (15) , pp. 2656-2664. 10.1182/blood-2009-12-260026

Bradshaw, Angela C., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Duffy, Margaret R., Coughlan, Lynda, van Rooijen, Nico, Kahari, Veli-Matti, Nicklin, Stuart A. and Baker, Andrew H. 2010. Requirements for receptor engagement during infection by adenovirus complexed with blood coagulation factor X. Plos Pathogens 6 (10) , e1001142. 10.1371/journal.ppat.1001142

Coughlan, Lynda, Alba, Raul, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Bradshaw, Angela C., McNeish, Iain A., Nicklin, Stuart A. and Baker, Andrew H. 2010. Tropism-modification strategies for targeted gene delivery using adenoviral vectors. Viruses 2 (10) , pp. 2290-2355. 10.3390/v2102290

Duffy, Margaret R., Bradshaw, Angela C., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Nicklin, Stuart A., McVey, John H. and Baker, Andrew H. 2010. Modification of the factor X serine protease domain ablates heparan sulfate proteoglycan engagement by Ad5-FX complexes. Human Gene Therapy 21 (9) , p. 1187. 10.1089/hum.2010.804

Collins, Louise, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Gehman, John D., Eckley, Lorna, Perugini, Matthew A., Separovic, Frances and Fabre, John W. 2010. Self-assembly of peptides into spherical nanoparticles for delivery of hydrophilic moieties to the cytosol. ACS Nano 4 (5) , pp. 2856-2864. 10.1021/nn901414q

Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Alba, Raul, Barouch, D. H., Delles, C. and Baker, Andrew H. 2010. In vitro evaluation of hexon modifications on the capacity of Ad5 to evade neutralising antibodies. Human Gene Therapy 21 (4) , p. 518. 10.1089/hum.2010.1225

Duffy, Margaret R., Bradshaw, Angela C., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Nicklin, Stuart A., McVey, John H. and Baker, Andrew H. 2010. Modification of the FX serine protease domain ablates HSGP engagment by Ad5/FX complexes. Human Gene Therapy 21 (4) , pp. 512-513. 10.1089/hum.2010.1225

Alba, Raul, Bradshaw, Angela C., McDonald, Robert A., Coughlan, Lynda, Parker, Alan ORCID: https://orcid.org/0000-0002-9302-1761, Miller, Ashley M., van Rooijen, Nico, Nicklin, Stuart A. and Baker, Andrew H. 2010. Biodistribution and inflammatory profiles of hepatocyte-detargeted FX-binding ablated Ad5 vectors. Human Gene Therapy 21 (4) , pp. 498-499. 10.1089/hum.2010.1224

Greig, Jenny A., Buckley, Suzanne M. K., Waddington, Simon N., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Bhella, David, Pink, Rebecca, Rahim, Ahad A., Morita, Takashi, Nicklin, Stuart A., Mcvey, John H. and Baker, Andrew H. 2009. Influence of coagulation factor X on in vitro and in vivo gene delivery by adenovirus (Ad) 5, Ad35, and chimeric Ad5/Ad35 vectors. Molecular Therapy 17 (10) , pp. 1683-1691. 10.1038/mt.2009.152

Alba, Raul, Bradshaw, Angela C., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Bhella, David, Waddington, Simon N., Nicklin, Stuart A., van Rooijen, Nico, Custers, Jerome, Goudsmit, Jaap, Barouch, Dan, Mcvey, John H. and Baker, Andrew H. 2009. Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer. Blood 114 (5) , pp. 965-971. 10.1182/blood-2009-03-208835

Greig, Jenny A., Buckley, Suzanne M. K., Waddington, Simon N., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Bhella, D., Pink, R., Morita, T., Custers, Jerome, Goudsmit, J., Nicklin, Stuart A., Mcvey, John H. and Baker, Andrew H. 2009. Influence of factor X on in vitro and in vivo gene delivery by Ad5 and Ad35 vectors. Molecular Therapy 17 , S325-S325.

Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Waddington, Simon N., Miller, A. M., Buckley, Suzanne M., Nicklin, Stuart A., McClure, J. D., McBride, M. W., Lee, W., McVey, John H. and Baker, Andrew H. 2009. Genome wide and micro RNA profiling of murine livers following acute phase intravenous delivery of Ad5 reveals subsets of hepatocyte and kupffer cell regulated genes. Molecular Therapy 17 , S43-S44.

Alba, R., Bradshaw, Angela C., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Bhella, D., Nicklin, Stuart A., Waddington, Simon N., Custers, Jerome, Goudsmit, J., Van Rooijen, Nico, Barouch, D. H., MacVey, John H. and Baker, Andrew H. 2009. Selected modification of the adenovirus type 5 hexon modulates interaction with coagulation factor X and hepatocyte transduction in vivo. Molecular Therapy 17 , S6-S6.

Parker, Alan ORCID: https://orcid.org/0000-0002-9302-1761, Waddington, Simon N., Buckley, Suzanne M. K., Custers, Jerome, Havenga, M. J. E., van Rooijen, Nico., Goudsmit, J., Mcvey, John H., Nicklin, Stuart A. and Baker, Andrew H. 2009. Effect of neutralizing sera on factor x-mediated adenovirus serotype 5 gene transfer. Journal of Virology 83 (1) , pp. 479-483. 10.1128/JVI.01878-08

Parker, Alan ORCID: https://orcid.org/0000-0002-9302-1761, Nicklin, Stuart A. and Baker, Andrew H. 2008. Interactions of adenovirus vectors with blood: Implications for intravascular gene therapy applications. Current Opinion in Molecular Therapeutics 10 (5) , pp. 439-448.

Waddington, Simon N., Mcvey, John H., Bhella, D., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Barker, K., Atoda, K., Pink, R., Buckley, Suzanne M. K., Greig, Jenny A., Denby, Laura, Custers, Jerome, Morita, T., Francischetti, I. M. B., Monteiro, R. Q., Barouch, D. H., van Rooijen, Nico, Napoli, C., Havenga, M., Nicklin, Stuart A, and Baker, Andrew H. 2008. A critical role for the adenovirus serotype 5 hexon in liver gene transfer. Human Gene Therapy 19 (4) , p. 409. 10.1089/hum.2008.1327

Parker, Alan ORCID: https://orcid.org/0000-0002-9302-1761, McVey, John H., Waddington, Simon N., Buckley, Suzanne M. K., Francischetti, I. M. B., Monteiro, R. Q., Nicklin, Stuart A. and Baker, Andrew H. 2008. An exosite within the human FX serine protease domain mediates cell transduction of AD5: FX complexes. Human Gene Therapy 19 (4) , p. 407. 10.1089/hum.2008.1327

Greig, Jenny A., Mcvey, John H., Waddington, Simon N., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Buckley, Suzanne M. K., Havenga, M. J. E., Nicklin, Stuart A. and Baker, Andrew H. 2008. Factor X enhances binding and transduction of human cancer cell lines by adenovirus (Ad) serotype 5 vectors but not by Ad35. Human Gene Therapy 19 (4) , p. 398.

Waddington, Simon N., Mcvey, John H., Bhella, David, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Barker, Kristeen, Atoda, Hideko, Pink, Rebecca, Buckley, Suzanne M. K., Greig, Jenny A., Denby, Laura, Custers, Jerome, Morita, Takashi, Francischetti, Ivo M. B., Monteiro, Robson Q., Barouch, Dan H., van Rooijen, Nico, Napoli, Claudio, Havenga, Menzo J. L., Nicklin, Stuart A. and Baker, Andrew H. 2008. Adenovirus serotype 5 hexon mediates liver gene transfer. Cell 132 (3) , pp. 397-409. 10.1016/j.cell.2008.01.016

Kubo, Naoki, Akita, Noriyuki, Shimizu, Akira, Kitahara, Hiroe, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 and Miyagawa, Shinichi 2008. Identification of oligopeptide binding to colon cancer cells separated from patients using laser capture microdissection. Journal of Drug Targeting 16 (5) , pp. 396-404. 10.1080/10611860802088796

Waddington, Simon N., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Havenga, Menzo, Nicklin, Stuart A., Buckley, Suzanne M. K., McVey, John H. and Baker, Andrew H. 2007. Targeting of adenovirus serotype 5 (Ad5) and 5/47 pseudotyped vectors in vivo: Fundamental involvement of coagulation factors and redundancy of CAR binding by Ad5. Journal of Virology 81 (17) , pp. 9568-9571. 10.1128/JVI.00663-07

Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Eckley, Lorna, Singh, Surjeet, Preece, Jon A., Collins, Louise and Fabre, John W. 2007. (LYS)(16)-based reducible polycations provide stable polyplexes with anionic fusogenic peptides and efficient gene delivery to post mitotic cells. Biochimica et Biophysica Acta (BBA) - General Subjects 1770 (9) , pp. 1331-1337. 10.1016/j.bbagen.2007.06.009

Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, McVey, John H., Doctor, Jessica H., Lopez-Franco, Oscar, Waddington, Simon N., Havenga, Menzo J. E., Nicklin, Stuart A. and Baker, Andrew H. 2007. Influence of coagulation factor zymogens on the infectivity of adenoviruses pseudotyped with fibers from subgroup D. Journal of Virology 81 (7) , pp. 3627-3631. 10.1128/JVI.02786-06

Maruta, Fukuto, Akita, Noriyuki, Nakayama, Jun, Miyagawa, Sinichi, Ismail, Tariq, Rowlands, David C., Kerr, David J., Fisher, Kerry D., Seymour, Leonard W. and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2007. Bacteriophage biopanning in human tumour biopsies to identify cancer-specific targeting ligands. Journal of Drug Targeting 15 (4) , pp. 311-319. 10.1080/10611860701195510

Akita, Noriyuki, Maruta, Fukuto, Seymour, Leonard W., Kerr, David J., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Asai, Tomohiro, Oku, Naoto, Nakayama, Jun and Miyagawa, Shinichi 2006. Identification of oligopeptides binding to peritoneal tumors of gastric cancer. Cancer Science 97 (10) , pp. 1075-1081. 10.1111/j.1349-7006.2006.00291.x

Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Waddington, Simon N., Nicol, Campbell G., Shayakhmetov, Dmitry M., Buckley, Suzanne M., Denby, Laura, Kemball-Cook, Geoffrey, Ni, Shaoheng, Lieber, Andre, McVey, John H., Nicklin, Stuart A. and Baker, Andrew H. 2006. Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes. Blood 108 (8) , pp. 2554-2561. 10.1182/blood-2006-04-008532

Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Nicol, Campbell G., Waddington, Simon N., Buckley, Suzanne M., Shayakhmetov, Dmitry M., Ni, Shaoheng H., Lieber, Andre, McVey, John H., Denby, Laura, Nicklin, Stuart A. and Baker, Andrew H. 2006. Hepatic tropism of adenoviral type 5 vectors can be mediated by multiple coagulation factors. Molecular Therapy 13 (S1) , S143-S143. 10.1016/j.ymthe.2006.08.436

Shimizu, A., Maruta, F., Akita, N., Miwa, S., Seymour, L. W., Kerr, D. J., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 and Miyagawa, S. 2006. Identification of an oligopeptide binding to hepatocellular carcinoma. Oncology 71 (1-2) , pp. 136-145. 10.1159/000100479

Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Collins, Louise, Zhang, X. H. and Fabre, John W. 2005. Exploration of peptide motifs for potent non-viral gene delivery highly selective for dividing cells. Journal of Gene Medicine 7 (12) , pp. 1545-1554. 10.1002/jgm.809

Read, Martin L., Spice, Rachel, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Mir, Sohaib and Logan, Ann 2005. 12th Annual Congress of the European Society of Gene Therapy. Expert Opinion on Biological Therapy 5 (1) , pp. 137-141. 10.1517/14712598.5.1.137

Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Fisher, Kerry D., Oupicky, David, Read, Martin L., Nicklin, Stuart A., Baker, Andrew H. and Seymour, Leonard W. 2005. Enhanced gene transfer activity of peptide-targeted gene-delivery vectors. Journal of Drug Targeting 13 (1) , pp. 39-51. 10.1080/10611860400020449

Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Collins, Louise, Zhang, X. H. and Fabre, John W. 2004. Free and (Lys)(16) containing fusogenic peptides for non-viral gene delivery to dividing and post mitotic cells. Journal of Gene Medicine 6 (9) , S13-S13.

Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Newman, Christopher, Briggs, Simon, Seymour, Leonard and Sheridan, Paul J. 2004. Nonviral gene delivery: techniques and implications for molecular medicine. Expert Reviews in Molecular Medicine 5 , pp. 1-15. 10.1017/S1462399403006562

Maruta, Fukuto, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Fisher, Kerry D., Murray, Paul G., Kerr, David J. and Seymour, Leonard W. 2003. Use of a phage display library to identify oligopeptides binding to the lumenal surface of polarized endothelium by ex vivo perfusion of human umbilical veins. Journal of Drug Targeting 11 (1) , pp. 53-59.

Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 and Seymour, Leonard W. 2002. Targeting of polyelectrolyte RNA complexes to cell surface integrins as an efficient cytoplasmic transfection mechanism. Journal of Bioactive and Compatible Polymers 17 (4) , pp. 229-238. 10.1106/088391102027977

Maruta, Fukuto, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Fisher, Kerry D., Hallissey, Michael T., Ismail, Tariq, Rowlands, David C., Chandler, Lois A., Kerr, David J. and Seymour, Leonard W. 2002. Identification of FGF receptor-binding peptides for cancer gene therapy. Cancer Gene Therapy 9 (6) , pp. 543-552. 10.1038/sj.cgt.7700470

Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Oupicky, David, Dash, Philip R. and Seymour, Leonard W. 2002. Methodologies for monitoring, nanoparticle formation by self-assembly of DNA with poly(L-lysine). Analytical Biochemistry 302 (1) , pp. 75-80. 10.1006/abio.2001.5507

Oupicky, David, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 and Seymour, Leonard W. 2002. Laterally stabilized complexes of DNA with linear reducible polycations: Strategy for triggered intracellular activation of DNA delivery vectors. Journal of the American Chemical Society 124 (1) , pp. 8-9. 10.1021/ja016440n

Carlisle, R. C., Fisher, K. D., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 and Seymour, Leonard W. 2000. Systems for gene delivery based on combination of viral and non-viral vectors. Targeting of Drugs 323 , pp. 117-125.