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Investigating endothelial cell transduction and hexon: platelet factor 4 binding of ChAdOx1 in the context of vaccine-induced thrombotic thrombocytopenia.
Journal of Thrombosis and Haemostasis
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Nicolson, Pip, Abrams, Simon, Amirthalingam, Gayatri, Brown, Kevin, Buka, Richard, Caulfield, Mark J., Gardner, Joshua, Goldblatt, David, Lovatt, Charlotte, Montague, Samantha, Naisbitt, Dean, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Pavord, Sue, Ramsay, Mary Elizabeth, Sterne, Jonathan A. C., Sudlow, Cathie, Toh, Cheng-Hok, Watson, Steve, Wang, Guozheng, Wood, Angela, Pirmohamed, Munir and TTS Consortium
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Curiel, David T. and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, eds.
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Adenoviral vectors for gene therapy.
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Bayliss, Rebecca J. ORCID: https://orcid.org/0000-0002-3324-957X and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761
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GP73: the key to unlocking immunotherapies efficacy in solid tumors?
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Swift, Emma A. and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761
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Adenoviral vector targeting.
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A pseudotyped adenovirus serotype 5 vector with serotype 49 fiber knob is an effective vector for vaccine and gene therapy applications.
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Gardner, Joshua, Abrams, Simon Timothy, Toh, Cheng-Hock, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Lovatt, Charlotte, Nicolson, Phillip L. R., Watson, Steve P., Grice, Sophie, Hering, Luisa, Pirmohamed, Munir and Naisbitt, Dean J.
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Identification of cross reactive T cell responses in adenovirus based COVID 19 vaccines.
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Preston, Hannah E., Bayliss, Rebecca ORCID: https://orcid.org/0000-0002-3324-957X, Temperton, Nigel, Neto, Martin Mayora, Brewer, Jason and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761
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Capture and inactivation of viral particles from bioaerosols by electrostatic precipitation.
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Othman, Maha, Baker, Alexander T. ORCID: https://orcid.org/0000-0001-8232-0531, Gupalo, Elena, Elsebaie, Abdelrahman, Bliss, Carly M., Rondina, Matthew T., Lillicrap, David and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761
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Corrigendum to To clot or not to clot? Ad is the question?Insights on mechanisms related to vaccine-induced thrombotic thrombocytopenia [J Thromb Haemost. 2021 Nov;19(11):2845-2856. doi: 10.1111/jth.15485].
Journal of Thrombosis and Haemostasis
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Swift, Emma A., Pollard, Steven M. and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761
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Engineering cancer selective virotherapies: are the pieces of the puzzle falling into place?
Human Gene Therapy
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Cunliffe, Tabitha G., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 and Jaramillo, Alfonso
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Pseudotyping bacteriophage P2 tail fibers to extend the host range for biomedical applications.
ACS Synthetic Biology
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Development of a low seroprevalence, αvβ6 integrin selective virotherapy based on human adenovirus type 10.
Molecular Therapy - Oncolytics
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Toh, Cheng-Hock, Wang, Guozheng and Parker, Alan L ORCID: https://orcid.org/0000-0002-9302-1761
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The aetiopathogenesis of vaccine-induced immune thrombotic thrombocytopenia.
Clinical Medicine
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Tate, Sophia J., Van de Sande, Leen, Ceelen, Wim P., Torkington, Jared and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761
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The feasibility of Pressurised Intraperitoneal Aerosolised Virotherapy (PIPAV) to administer oncolytic adenoviruses.
Pharmaceutics
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Baker, Alexander T., Boyd, Ryan J., Sarkar, Daipayan, Teijeira Crespo, Alicia, Chan, Chun Kit, Bates, Emily, Waraich, Kasim, Vant, John, Wilson, Eric, Truong, Chloe D., Lipka-Lloyd, Magdalena, Fromme, Petra, Vermaas, Josh, Williams, Dewight, Machiesky, LeeAnn, Heurich, Meike ORCID: https://orcid.org/0000-0003-0105-2702, Nagalo, Bolni M., Coughlan, Lynda, Umlauf, Scott, Chiu, Po-Lin, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Cohen, Taylor S., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Singharoy, Abhishek and Borad, Mitesh J.
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ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome.
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To clot or not to clot? Ad is the question - insights on mechanisms related to vaccine induced thrombotic thrombocytopenia.
Journal of Thrombosis and Haemostasis
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10.1111/jth.15485
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Nestic, Davor, Bozinovic, Ksenija, Pehar, Isabela, Wallace, Rebecca, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 and Majhen, Dragomira
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The revolving door of adenovirus cell entry: not all pathways are equal.
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In vitro and in vivo evaluation of human adenovirus type 49 as a vector for therapeutic applications.
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Efficient intravenous tumor targeting using the αvβ6 integrin-selective precision virotherapy Ad5NULL-A20.
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Wongthida, Phonphimon, Schuelke, Matthew R., Driscoll, Christopher B., Kottke, Timothy, Thompson, Jill M, Tonne, Jason, Stone, Cathy, Huff, Amanda L., Wetmore, Cynthia, Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Evgin, Laura and Vile, Richard G.
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Ad-CD40L mobilizes CD4 T cells for the treatment of brainstem tumors.
Neuro-Oncology
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Mowbray, N. G., Ansell, J., Horwood, J., Cornish, J., Rizkallah, P. ORCID: https://orcid.org/0000-0002-9290-0369, Parker, A. ORCID: https://orcid.org/0000-0002-9302-1761, Wall, P., Spinelli, A. and Torkington, J.
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Safe management of surgical smoke in the age of COVID-19.
British Journal of Surgery
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Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1.
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Man, Stella, Foster, Julie, Carapuca, Elisabete, Davies, James A ORCID: https://orcid.org/0000-0003-3569-4500, Parker, Alan ORCID: https://orcid.org/0000-0002-9302-1761, Sosabowski, Jane and Hallden, Gunnel
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Systemic delivery and SPECT/CT in vivo imaging of 125I-labelled oncolytic adenoviral mutants in models of pancreatic cancer.
Scientific Reports
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Adenovirus serotype 26 utilises sialic acid bearing glycans as a primary cell entry receptor.
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Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactions.
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Ad5NULL-A20 - a tropism-modified, αvβ6 integrin-selective oncolytic adenovirus for epithelial ovarian cancer therapies.
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Designer oncolytic adenovirus: coming of age.
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Histone deacetylase inhibitor trichostatin A sensitises cisplatin-resistant ovarian cancer cells to oncolytic adenovirus.
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The novel oncolytic adenoviral mutant Ad5-3Δ-A20T retargeted to αvβ6 integrins efficiently eliminates pancreatic cancer cells.
Molecular Cancer Therapeutics
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Uusi-Kerttula, Hanni and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761
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Precision virotherapies: Coming soon.
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Yan, Bing, Wang, Zengbo, Parker, Alan ORCID: https://orcid.org/0000-0002-9302-1761, Lai, Yukun ORCID: https://orcid.org/0000-0002-2094-5680, Thomas, John P., Yue, Liyang and Monks, James N.
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Superlensing microscope objective lens.
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Robertson, Stacy, Alba, Raul, Duffy, Margeret R., Clarke, Carolyn, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Nicklin, Stuart A. and Baker, Andrew H.
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Retargeting FX binding-ablated HAdV-5 to vascular cells by inclusion of the RGD-4C peptide in hexon hypervariable region 7 and the HI loop.
Journal of General Virology
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Evaluation of CD46 re-targeted adenoviral vectors for clinical ovarian cancer intraperitoneal therapy.
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Pseudotyped αvβ6 integrin-targeted adenovirus vectors for ovarian cancer therapies.
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Incorporation of avß6 integrin-targeting peptide into chimaeric Ad5/fibre knob 48 vector results in efficient tumour-targeting and evasion of neutralisation in clinical ascites.
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Development of an Ad5 vector pseudotyped with Ad48 knob protein and targeted to αvβ6 integrin efficiently targets tumour cells and evades pre-existing immunity in clinical ascites.
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Modulation of Ad5 fibre knob as a means of circumventing pre-existing immunity in clinical ovarian ascites.
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Evaluation of CD46 utilising adenoviral vectors for clinical ovarian cancer applications [Abstract].
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Incorporation of peptides targeting EGFR and FGFR1 into
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targeted cancer therapies.
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Efficient transduction of primary vascular cells by the rare adenovirus serotype 49 vector.
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Nivsarkar, Megha S., Buckley, Suzanne M. K., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Perocheau, Dany, McKay, Tristan R., Rahim, Ahad A., Howe, Steven J. and Waddington, Simon N.
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Evidence for contribution of CD4+CD25+ regulatory T cells in maintaining immune tolerance to human factor IX following perinatal adenovirus vector delivery.
Journal of Immunology Research
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Guinn, Barbara-ann, Braidwood, Lynne, Parker, Alan ORCID: https://orcid.org/0000-0002-9302-1761, Peng, Kah-Whye and Seymour, Leonard
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Efficient gene transfer to human vascular cells in vitro and ex vivo using adenovirus serotype 49.
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Coughlan, Lynda, Uusi-Kerttula, Hanni, Ma, Jiangtao, Degg, Bethany P., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 and Baker, Andrew H.
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Retargeting adenovirus serotype 48 fiber knob domain by peptide incorporation.
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Pseudotyping the adenovirus serotype 5 capsid with both the fibre and penton of serotype 35 enhances vascular smooth muscle cell transduction.
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Assessment of a novel, capsid-modified adenovirus with an improved vascular gene transfer profile.
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Kaur, H., Toukh, M., Corscadden, K., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 and Othman, M.
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Fucoidan improves adenovirus mediated thrombocytopenia and enhances viral liver transduction [Abstract].
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Duffy, Margaret R., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Kalkman, Eric R., White, Katie, Kovalskyy, Dmytro, Kelly, Sharon M. and Baker, Andrew H.
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Identification of novel small molecule inhibitors of adenovirus gene transfer using a high throughput screening approach.
Journal of Controlled Release
170
(1)
, pp. 132-140.
10.1016/j.jconrel.2013.05.007
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Coughlan, Lynda, Bradshaw, Angela C., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Robinson, Hollie, White, Katie, Custers, Jerome, Goudsmit, Jaap, Van Roijen, Nico, Barouch, Dan H., Nicklin, Stuart A. and Baker, Andrew H.
2012.
Ad5:Ad48 hexon hypervariable region substitutions lead to toxicity and increased inflammatory responses following intravenous delivery.
Molecular Therapy
20
(12)
, pp. 2268-2281.
10.1038/mt.2012.162
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|
Duffy, Margaret R., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Bradshaw, Angela C. and Baker, Andrew H.
2012.
Manipulation of adenovirus interactions with host factors for gene therapy applications.
Nanomedicine
7
(2)
, pp. 271-288.
10.2217/nnm.11.186
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Coughlan, Lynda, Uusi-Kerttula, Hanni, Degg, B., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Custers, Jerome, Nicklin, Stuart A. and Baker, Andrew H.
2011.
In vitro assessment of targeting peptide incorporation within the knob domain of human adenovirus type 48 fiber.
Human Gene Therapy
22
(10)
, A128-A128.
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Duffy, Margaret R., Bradshaw, Angela C., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, McVey, John H. and Baker, Andrew H.
2011.
A Cluster of Basic Amino Acids in the Factor X Serine Protease Mediates Surface Attachment of Adenovirus/FX Complexes.
Journal of Virology
85
(20)
, pp. 10914-10919.
10.1128/JVI.05382-11
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|
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Duffy, M. R., Bradshaw, A. C., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, McVey, J. H. and Baker, A. H.
2011.
A cluster of basic amino acids in the factor X serine protease mediate surface attachment of adenovirus:FX complexes [Abstract].
Human Gene Therapy
22
(10)
, A34-A34.
10.1089/hum.2011.2525
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Kitahara, Hiroe, Masumoto, Junya, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Maruta, Fukuto, Kubo, Naoki, Shimizu, Akira, Akita, Noriyuko, Miwa, Shiro, Kobayashi, Naoya, Nakayama, Jun and Miyagawa, Shinichi
2011.
COP35, a cholangiocarcinoma-binding oligopeptide, interacts with the clathrin heavy chain accompanied by GRP78.
Molecular Cancer Research
9
(6)
, pp. 688-701.
10.1158/1541-7786.MCR-10-0470
|
|
Othman, Maha, Chirinian, Yvette, Brown, Christine, Notley, Colleen, Hickson, Nicholas, Hampshire, Daniel, Buckley, Suzanne, Waddington, Simon, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Baker, Andrew, James, Paula and Lillicrap, David
2010.
Functional characterization of a 13-bp deletion (c.-1522_-1510del13) in the promoter of the von Willebrand factor gene in type 1 von Willebrand disease.
Blood
116
(18)
, pp. 3645-3652.
10.1182/blood-2009-12-261131
|
|
Alba, Raul, Bradshaw, Angela C., Coughlan, Lynda, Denby, Laura, McDonald, Robert A., Waddington, Simon N., Buckley, Suzanne M. K., Greig, Jenny A., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Miller, Ashley M., Wang, Hongjie, Lieber, Andre, van Rooijen, Nico, McVey, John H,, Nicklin, Stuart A. and Baker, Andrew H.
2010.
Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors.
Blood
116
(15)
, pp. 2656-2664.
10.1182/blood-2009-12-260026
|
|
Bradshaw, Angela C., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Duffy, Margaret R., Coughlan, Lynda, van Rooijen, Nico, Kahari, Veli-Matti, Nicklin, Stuart A. and Baker, Andrew H.
2010.
Requirements for receptor engagement during infection by adenovirus complexed with blood coagulation factor X.
Plos Pathogens
6
(10)
, e1001142.
10.1371/journal.ppat.1001142
|
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Coughlan, Lynda, Alba, Raul, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Bradshaw, Angela C., McNeish, Iain A., Nicklin, Stuart A. and Baker, Andrew H.
2010.
Tropism-modification strategies for targeted gene delivery using adenoviral vectors.
Viruses
2
(10)
, pp. 2290-2355.
10.3390/v2102290
|
|
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Duffy, Margaret R., Bradshaw, Angela C., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Nicklin, Stuart A., McVey, John H. and Baker, Andrew H.
2010.
Modification of the factor X serine protease domain ablates heparan sulfate proteoglycan engagement by Ad5-FX complexes.
Human Gene Therapy
21
(9)
, p. 1187.
10.1089/hum.2010.804
|
|
Collins, Louise, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Gehman, John D., Eckley, Lorna, Perugini, Matthew A., Separovic, Frances and Fabre, John W.
2010.
Self-assembly of peptides into spherical nanoparticles for delivery of hydrophilic moieties to the cytosol.
ACS Nano
4
(5)
, pp. 2856-2864.
10.1021/nn901414q
|
|
Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Alba, Raul, Barouch, D. H., Delles, C. and Baker, Andrew H.
2010.
In vitro evaluation of hexon modifications on the capacity of Ad5 to evade neutralising antibodies.
Human Gene Therapy
21
(4)
, p. 518.
10.1089/hum.2010.1225
|
|
Duffy, Margaret R., Bradshaw, Angela C., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Nicklin, Stuart A., McVey, John H. and Baker, Andrew H.
2010.
Modification of the FX serine protease domain ablates HSGP engagment by Ad5/FX complexes.
Human Gene Therapy
21
(4)
, pp. 512-513.
10.1089/hum.2010.1225
|
|
Alba, Raul, Bradshaw, Angela C., McDonald, Robert A., Coughlan, Lynda, Parker, Alan ORCID: https://orcid.org/0000-0002-9302-1761, Miller, Ashley M., van Rooijen, Nico, Nicklin, Stuart A. and Baker, Andrew H.
2010.
Biodistribution and inflammatory profiles of hepatocyte-detargeted FX-binding ablated Ad5 vectors.
Human Gene Therapy
21
(4)
, pp. 498-499.
10.1089/hum.2010.1224
|
|
Greig, Jenny A., Buckley, Suzanne M. K., Waddington, Simon N., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Bhella, David, Pink, Rebecca, Rahim, Ahad A., Morita, Takashi, Nicklin, Stuart A., Mcvey, John H. and Baker, Andrew H.
2009.
Influence of coagulation factor X on in vitro and in vivo gene delivery by adenovirus (Ad) 5, Ad35, and chimeric Ad5/Ad35 vectors.
Molecular Therapy
17
(10)
, pp. 1683-1691.
10.1038/mt.2009.152
|
|
Alba, Raul, Bradshaw, Angela C., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Bhella, David, Waddington, Simon N., Nicklin, Stuart A., van Rooijen, Nico, Custers, Jerome, Goudsmit, Jaap, Barouch, Dan, Mcvey, John H. and Baker, Andrew H.
2009.
Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer.
Blood
114
(5)
, pp. 965-971.
10.1182/blood-2009-03-208835
|
|
Greig, Jenny A., Buckley, Suzanne M. K., Waddington, Simon N., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Bhella, D., Pink, R., Morita, T., Custers, Jerome, Goudsmit, J., Nicklin, Stuart A., Mcvey, John H. and Baker, Andrew H.
2009.
Influence of factor X on in vitro and in vivo gene delivery by Ad5 and Ad35 vectors.
Molecular Therapy
17
, S325-S325.
|
|
Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Waddington, Simon N., Miller, A. M., Buckley, Suzanne M., Nicklin, Stuart A., McClure, J. D., McBride, M. W., Lee, W., McVey, John H. and Baker, Andrew H.
2009.
Genome wide and micro RNA profiling of murine livers following acute phase intravenous delivery of Ad5 reveals subsets of hepatocyte and kupffer cell regulated genes.
Molecular Therapy
17
, S43-S44.
|
|
Alba, R., Bradshaw, Angela C., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Bhella, D., Nicklin, Stuart A., Waddington, Simon N., Custers, Jerome, Goudsmit, J., Van Rooijen, Nico, Barouch, D. H., MacVey, John H. and Baker, Andrew H.
2009.
Selected modification of the adenovirus type 5 hexon modulates interaction with coagulation factor X and hepatocyte transduction in vivo.
Molecular Therapy
17
, S6-S6.
|
|
Parker, Alan ORCID: https://orcid.org/0000-0002-9302-1761, Waddington, Simon N., Buckley, Suzanne M. K., Custers, Jerome, Havenga, M. J. E., van Rooijen, Nico., Goudsmit, J., Mcvey, John H., Nicklin, Stuart A. and Baker, Andrew H.
2009.
Effect of neutralizing sera on factor x-mediated adenovirus serotype 5 gene transfer.
Journal of Virology
83
(1)
, pp. 479-483.
10.1128/JVI.01878-08
|
|
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Parker, Alan ORCID: https://orcid.org/0000-0002-9302-1761, Nicklin, Stuart A. and Baker, Andrew H.
2008.
Interactions of adenovirus vectors with blood: Implications for intravascular gene therapy applications.
Current Opinion in Molecular Therapeutics
10
(5)
, pp. 439-448.
|
|
Waddington, Simon N., Mcvey, John H., Bhella, D., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Barker, K., Atoda, K., Pink, R., Buckley, Suzanne M. K., Greig, Jenny A., Denby, Laura, Custers, Jerome, Morita, T., Francischetti, I. M. B., Monteiro, R. Q., Barouch, D. H., van Rooijen, Nico, Napoli, C., Havenga, M., Nicklin, Stuart A, and Baker, Andrew H.
2008.
A critical role for the adenovirus serotype 5 hexon in liver gene transfer.
Human Gene Therapy
19
(4)
, p. 409.
10.1089/hum.2008.1327
|
|
Parker, Alan ORCID: https://orcid.org/0000-0002-9302-1761, McVey, John H., Waddington, Simon N., Buckley, Suzanne M. K., Francischetti, I. M. B., Monteiro, R. Q., Nicklin, Stuart A. and Baker, Andrew H.
2008.
An exosite within the human FX serine protease domain mediates cell transduction of AD5: FX complexes.
Human Gene Therapy
19
(4)
, p. 407.
10.1089/hum.2008.1327
|
|
Greig, Jenny A., Mcvey, John H., Waddington, Simon N., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Buckley, Suzanne M. K., Havenga, M. J. E., Nicklin, Stuart A. and Baker, Andrew H.
2008.
Factor X enhances binding and transduction of human cancer cell lines by adenovirus (Ad) serotype 5 vectors but not by Ad35.
Human Gene Therapy
19
(4)
, p. 398.
|
|
Waddington, Simon N., Mcvey, John H., Bhella, David, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Barker, Kristeen, Atoda, Hideko, Pink, Rebecca, Buckley, Suzanne M. K., Greig, Jenny A., Denby, Laura, Custers, Jerome, Morita, Takashi, Francischetti, Ivo M. B., Monteiro, Robson Q., Barouch, Dan H., van Rooijen, Nico, Napoli, Claudio, Havenga, Menzo J. L., Nicklin, Stuart A. and Baker, Andrew H.
2008.
Adenovirus serotype 5 hexon mediates liver gene transfer.
Cell
132
(3)
, pp. 397-409.
10.1016/j.cell.2008.01.016
|
|
Kubo, Naoki, Akita, Noriyuki, Shimizu, Akira, Kitahara, Hiroe, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 and Miyagawa, Shinichi
2008.
Identification of oligopeptide binding to colon cancer cells separated from patients using laser capture microdissection.
Journal of Drug Targeting
16
(5)
, pp. 396-404.
10.1080/10611860802088796
|
|
Waddington, Simon N., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Havenga, Menzo, Nicklin, Stuart A., Buckley, Suzanne M. K., McVey, John H. and Baker, Andrew H.
2007.
Targeting of adenovirus serotype 5 (Ad5) and 5/47 pseudotyped vectors in vivo: Fundamental involvement of coagulation factors and redundancy of CAR binding by Ad5.
Journal of Virology
81
(17)
, pp. 9568-9571.
10.1128/JVI.00663-07
|
|
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Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Eckley, Lorna, Singh, Surjeet, Preece, Jon A., Collins, Louise and Fabre, John W.
2007.
(LYS)(16)-based reducible polycations provide stable polyplexes with anionic fusogenic peptides and efficient gene delivery to post mitotic cells.
Biochimica et Biophysica Acta (BBA) - General Subjects
1770
(9)
, pp. 1331-1337.
10.1016/j.bbagen.2007.06.009
|
|
Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, McVey, John H., Doctor, Jessica H., Lopez-Franco, Oscar, Waddington, Simon N., Havenga, Menzo J. E., Nicklin, Stuart A. and Baker, Andrew H.
2007.
Influence of coagulation factor zymogens on the infectivity of adenoviruses pseudotyped with fibers from subgroup D.
Journal of Virology
81
(7)
, pp. 3627-3631.
10.1128/JVI.02786-06
|
|
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Maruta, Fukuto, Akita, Noriyuki, Nakayama, Jun, Miyagawa, Sinichi, Ismail, Tariq, Rowlands, David C., Kerr, David J., Fisher, Kerry D., Seymour, Leonard W. and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761
2007.
Bacteriophage biopanning in human tumour biopsies to identify cancer-specific targeting ligands.
Journal of Drug Targeting
15
(4)
, pp. 311-319.
10.1080/10611860701195510
|
|
Akita, Noriyuki, Maruta, Fukuto, Seymour, Leonard W., Kerr, David J., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Asai, Tomohiro, Oku, Naoto, Nakayama, Jun and Miyagawa, Shinichi
2006.
Identification of oligopeptides binding to peritoneal tumors of gastric cancer.
Cancer Science
97
(10)
, pp. 1075-1081.
10.1111/j.1349-7006.2006.00291.x
|
|
Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Waddington, Simon N., Nicol, Campbell G., Shayakhmetov, Dmitry M., Buckley, Suzanne M., Denby, Laura, Kemball-Cook, Geoffrey, Ni, Shaoheng, Lieber, Andre, McVey, John H., Nicklin, Stuart A. and Baker, Andrew H.
2006.
Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes.
Blood
108
(8)
, pp. 2554-2561.
10.1182/blood-2006-04-008532
|
|
Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Nicol, Campbell G., Waddington, Simon N., Buckley, Suzanne M., Shayakhmetov, Dmitry M., Ni, Shaoheng H., Lieber, Andre, McVey, John H., Denby, Laura, Nicklin, Stuart A. and Baker, Andrew H.
2006.
Hepatic tropism of adenoviral type 5 vectors can be mediated by multiple coagulation factors.
Molecular Therapy
13
(S1)
, S143-S143.
10.1016/j.ymthe.2006.08.436
|
|
Shimizu, A., Maruta, F., Akita, N., Miwa, S., Seymour, L. W., Kerr, D. J., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 and Miyagawa, S.
2006.
Identification of an oligopeptide binding to hepatocellular carcinoma.
Oncology
71
(1-2)
, pp. 136-145.
10.1159/000100479
|
|
Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Collins, Louise, Zhang, X. H. and Fabre, John W.
2005.
Exploration of peptide motifs for potent non-viral gene delivery highly selective for dividing cells.
Journal of Gene Medicine
7
(12)
, pp. 1545-1554.
10.1002/jgm.809
|
|
Read, Martin L., Spice, Rachel, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Mir, Sohaib and Logan, Ann
2005.
12th Annual Congress of the European Society of Gene Therapy.
Expert Opinion on Biological Therapy
5
(1)
, pp. 137-141.
10.1517/14712598.5.1.137
|
|
Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Fisher, Kerry D., Oupicky, David, Read, Martin L., Nicklin, Stuart A., Baker, Andrew H. and Seymour, Leonard W.
2005.
Enhanced gene transfer activity of peptide-targeted gene-delivery vectors.
Journal of Drug Targeting
13
(1)
, pp. 39-51.
10.1080/10611860400020449
|
|
Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Collins, Louise, Zhang, X. H. and Fabre, John W.
2004.
Free and (Lys)(16) containing fusogenic peptides for non-viral gene delivery to dividing and post mitotic cells.
Journal of Gene Medicine
6
(9)
, S13-S13.
|
|
Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Newman, Christopher, Briggs, Simon, Seymour, Leonard and Sheridan, Paul J.
2004.
Nonviral gene delivery: techniques and implications for molecular medicine.
Expert Reviews in Molecular Medicine
5
, pp. 1-15.
10.1017/S1462399403006562
|
|
Maruta, Fukuto, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Fisher, Kerry D., Murray, Paul G., Kerr, David J. and Seymour, Leonard W.
2003.
Use of a phage display library to identify oligopeptides binding to the lumenal surface of polarized endothelium by ex vivo perfusion of human umbilical veins.
Journal of Drug Targeting
11
(1)
, pp. 53-59.
|
|
Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 and Seymour, Leonard W.
2002.
Targeting of polyelectrolyte RNA complexes to cell surface integrins as an efficient cytoplasmic transfection mechanism.
Journal of Bioactive and Compatible Polymers
17
(4)
, pp. 229-238.
10.1106/088391102027977
|
|
Maruta, Fukuto, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Fisher, Kerry D., Hallissey, Michael T., Ismail, Tariq, Rowlands, David C., Chandler, Lois A., Kerr, David J. and Seymour, Leonard W.
2002.
Identification of FGF receptor-binding peptides for cancer gene therapy.
Cancer Gene Therapy
9
(6)
, pp. 543-552.
10.1038/sj.cgt.7700470
|
|
Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761, Oupicky, David, Dash, Philip R. and Seymour, Leonard W.
2002.
Methodologies for monitoring, nanoparticle formation by self-assembly of DNA with poly(L-lysine).
Analytical Biochemistry
302
(1)
, pp. 75-80.
10.1006/abio.2001.5507
|
|
Oupicky, David, Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 and Seymour, Leonard W.
2002.
Laterally stabilized complexes of DNA with linear reducible polycations: Strategy for triggered intracellular activation of DNA delivery vectors.
Journal of the American Chemical Society
124
(1)
, pp. 8-9.
10.1021/ja016440n
|
|
Carlisle, R. C., Fisher, K. D., Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 and Seymour, Leonard W.
2000.
Systems for gene delivery based on combination of viral and non-viral vectors.
Targeting of Drugs
323
, pp. 117-125.
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|



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