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Number of items: 67.

Zelek, Wioleta M., Harris, Claire L. and Morgan, Bryan Paul

2018. Extracting the barbs from complement assays: Identification and optimisation of a safe substitute for traditional buffers. Immunobiology 223 (12) , pp. 744-749. 10.1016/j.imbio.2018.07.016

Loveless, Sam

, Neal, James W., Howell, Owain W., Harding, Katharine E., Sarkies, Patrick, Evans, Rhian, Bevan, Ryan J., Hakobyan, Svetlana, Harris, Claire L., Robertson, Neil P.

and Morgan, Bryan Paul

2018. Tissue microarray methodology identifies complement pathway activation and dysregulation in progressive multiple sclerosis. Brain Pathology 28 (4) , pp. 507-520. 10.1111/bpa.12546

Calippe, Bertrand, Augustin, Sebastien, Beguier, Fanny, Charles-Messance, Hugo, Poupel, Lucie, Conart, Jean-Baptiste, Hu, Shulong J., Lavalette, Sophie, Fauvet, Alexandre, Rayes, Julie, Levy, Olivier, Raoul, William, Fitting, Catherine, Denèfle, Thomas, Pickering, Matthew C., Harris, Claire, Jorieux, Sylvie, Sullivan, Patrick M., Sahel, José-Alain, Karoyan, Philippe, Sapieha, Przemyslaw, Guillonneau, Xavier, Gautier, Emmanuel L. and Sennlaub, Florian 2017. Complement factor H inhibits CD47-Mediated resolution of inflammation. Immunity 46 (2) , pp. 261-272. 10.1016/j.immuni.2017.01.006

Hakobyan, Svetlana, Harding, Katharine, Aiyaz, Mohammed, Hye, Abdul, Dobson, Richard, Baird, Alison, Liu, Benjamine, Harris, Claire, Lovestone, Simon and Morgan, Bryan Paul

2016. Complement biomarkers as predictors of disease progression in Alzheimer's disease. Journal of Alzheimer's Disease 54 (2) , pp. 707-716. 10.3233/JAD-160420

Challis, Rachel C., Araujo, Geisilaine S. R., Wong, Edwin K. S., Anderson, Holly E., Awan, Atif, Dorman, Anthony M., Waldron, Mary, Wilson, Valerie, Brocklebank, Vicky, Strain, Lisa, Morgan, B. Paul

, Harris, Claire L., Marchbank, Kevin J., Goodship, Timothy H. J. and Kavanagh, David 2016. A de novo deletion in the regulators of complement activation cluster producing a hybrid complement factor H/complement factor H-related 3 gene in atypical hemolytic uremic syndrome. Journal of the American Society of Nephrology 27 (6) , pp. 1617-1624. 10.1681/ASN.2015010100

Ruseva, Marieta M., Ramaglia, Valeria, Morgan, B. Paul

and Harris, Claire L. 2015. An anticomplement agent that homes to the damaged brain and promotes recovery after traumatic brain injury in mice. Proceedings of the National Academy of Sciences 112 (46) , pp. 14319-14324. 10.1073/pnas.1513698112

Martínez-Barricarte, Rubén, Heurich-Sevcenco, Meike

, López-Perrote, Andrés, Tortajada, Agustin, Pinto, Sheila, López-Trascasa, Margarita, Sánchez-Corral, Pilar, Morgan, B. Paul

, Llorca, Oscar, Harris, Claire L. and Rodríguez de Córdoba, Santiago 2015. The molecular and structural bases for the association of complement C3 mutations with atypical hemolytic uremic syndrome. Molecular Immunology 66 (2) , pp. 263-273. 10.1016/j.molimm.2015.03.248

Giles, Joanna L., Choy, Ernest

, van den Berg, Carmen, Morgan, B. Paul

and Harris, Claire L. 2015. Response to comment on 'Functional analysis of a complement polymorphism (rs17611) associated with rheumatoid arthritis'. Journal of Immunology 195 (1) , p. 4. 10.4049/jimmunol.1500968

Sei, Yumi, Mizuno, Masashi, Suzuki, Yasuhiro, Imai, Masaki, Higashide, Keiko, Harris, Claire L., Sakata, Fumiko, Iguchi, Daiki, Fujiwara, Michitaka, Kodera, Yasuhiro, Maruyama, Shoichi, Matsuo, Seiichi and Ito, Yasuhiko 2015. Expression of membrane complement regulators, CD46, CD55 and CD59, in mesothelial cells of patients on peritoneal dialysis therapy. Molecular Immunology 65 (2) , pp. 302-309. 10.1016/j.molimm.2015.02.005

Owen, E. Patricia, Würzner, Reinhard, Leisegang, Felicity, Rizkallah, Pierre, Whitelaw, Andrew, Simpson, John, Thomas, Andrew David

, Harris, Claire Louise, Giles, Joanna L., Hellerud, Bernt C., Mollnes, Tom E., Morgan, Bryan Paul

, Potter, Paul C. and Orren, Ann 2015. A complement C5 gene mutation, c.754G>A:p.A252T, is common in the Western Cape, South Africa and found to be homozygous in seven percent of Black African meningococcal disease cases. Molecular Immunology 64 (1) , pp. 170-176. 10.1016/j.molimm.2014.11.010

Giles, Joanna, Choy, Ernest Ho Sing

, Van Den Berg, Carmen, Morgan, Bryan Paul

and Harris, Claire Louise 2015. Functional analysis of a complement polymorphism (rs17611) associated with rheumatoid arthritis. The Journal of Immunology 194 (7) , pp. 3029-3034. 10.4049/jimmunol.1402956

Giles, J. L.

, Choy, E.

, van den Berg, C., Morgan, B. P.

and Harris, C. L. 2014. Functional analysis of a complement polymorphism (rs17611) associated with Rheumatoid Arthritis. Immunology 143 (s2) , pp. 181-182. 10.1111/imm.12407

Wong, Edwin K.S., Anderson, Holly E., Herbert, Andrew P., Challis, Rachel C., Brown, Paul, Reis, Geisilaine, Tellez, James O., Strain, Lisa, Fluck, Nicholas, Humphrey, Ann, Macleod, Alison, Richards, Anna, Ahlert, Daniel, Santibanez-Koref, Mauro, Barlow, Paul N., Marchbank, Kevin J., Harris, Claire, Goodship, Timothy H.J. and Kavanagh, David 2014. Characterization of a factor H mutation that perturbs the alternative pathway of complement in a family with membranoproliferative GN. Journal of the American Society of Nephrology 25 (11) , pp. 2425-2433. 10.1681/ASN.2013070732

Paixao-Cavalcante, Danielle, Torreira, Eva, Lindorfer, Margaret A., Rodriguez de Cordoba, Santiago, Morgan, Bryan

, Taylor, Ronald P., Llorca, Oscar and Harris, Claire 2014. A humanized antibody that regulates the alternative pathway convertase: potential for therapy of renal disease associated with nephritic factors. The Journal of Immunology 192 (10) , pp. 4844-4851. 10.4049/jimmunol.1303131

Ingram, Gillian, Loveless, Sam

, Howell, Owain W., Hakobyan, Svetlana, Dancey, Bethan, Harris, Claire L., Robertson, Neil P.

, Neal, James W. and Morgan, B. Paul

2014. Complement activation in multiple sclerosis plaques: an immunohistochemical analysis. Acta Neuropathologica Communications 2 , 53. 10.1186/2051-5960-2-53

Wilson, V., Darlay, R., Wong, W., Wood, K., McFarlane, J., Schejbel, L., Schmidt, I., Harris, Claire Louise, Tellez, J., Hunze, E., Marchbank, K., Goodship, J. and Goodship, T. 2013. Genotype/Phenotype correlations in complement factor H deficiency arising from uniparental isodisomy. American Journal of Kidney Diseases 62 (5) , pp. 978-983. 10.1053/j.ajkd.2013.05.020

Pickering, Matthew C, D'Agati, Vivette D, Nester, Carla M, Smith, Richard J, Haas, Mark, Appel, Gerald B, Alpers, Charles E, Bajema, Ingeborg M, Bedrosian, Camille, Braun, Michael, Doyle, Mittie, Fakhouri, Fadi, Fervenza, Fernando C, Fogo, Agnes B, Frémeaux-Bacchi, Véronique, Gale, Daniel P, Goicoechea de Jorge, Elena, Griffin, Gene, Harris, Claire Louise, Holers, V Michael, Johnson, Sally, Lavin, Peter J, Medjeral-Thomas, Nicholas, Morgan, Bryan Paul

, Nast, Cynthia C, Noel, Laure-Hélène, Peters, D Keith, Rodríguez de Córdoba, Santiago, Servais, Aude, Sethi, Sanjeev, Song, Wen-Chao, Tamburini, Paul, Thurman, Joshua M, Zavros, Michael and Cook, H Terence 2013. C3 glomerulopathy: consensus report. Kidney International 84 (6) , pp. 1079-1089. 10.1038/ki.2013.377

Tortajada, Agustín, Yébenes, Hugo, Abarrategui-Garrido, Cynthia, Anter, Jaouad, García-Fernández, Jesús M., Martínez-Barricarte, Rubén, Alba-Domínguez, María, Malik, Talat H., Bedoya, Rafael, Pérez, Rocío Cabrera, Trascasa, Margarita López, Pickering, Matthew C., Harris, Claire Louise, Sánchez-Corral, Pilar, Llorca, Oscar and Rodríguez de Córdoba, Santiago 2013. C3 glomerulopathy-associated CFHR1 mutation alters FHR oligomerization and complement regulation. The Journal of Clinical Investigation 123 (6) , pp. 2434-2446. 10.1172/JCI68280

Gustafsson, M, Lannergard, J, Nilsson, O, Kristensen, B, Olsen, J, Harris, Claire Louise, Ufret-Vincenty, R, Stahlhammer-Carlemalm, M and Gunnar, L 2013. Factor H Binds to the hypervariable region of many streptococcus pyogenes M proteins but does not promote phagocytosis resistance or acute virulence. PLoS Pathogens 9 (4) , e1003323. 10.1371/journal.ppat.1003323

Goicoechea de Jorge, E., Caesar, J. J. E., Malik, T. H., Patel, M., Colledge, M., Johnson, S., Hakobyan, Svetlana, Morgan, Bryan Paul

, Harris, Claire Louise, Pickering, M. C. and Lea, S. M. 2013. Dimerization of complement factor H-related proteins modulates complement activation in vivo. Proceedings of the National Academy of Sciences of the United States of America 110 (12) , pp. 4685-4690. 10.1073/pnas.1219260110

Adriani, Kirsten S., Brouwer, Matthijs C., Geldhoff, Madelijn, Baas, Frank, Zwinderman, Aeilko H., Morgan, Bryan Paul

, Harris, Claire Louise, van der Ende, Arie and van de Beek, Diederik 2013. Common polymorphisms in the complement system and susceptiblity to bacterial meningitis. Journal of Infection 66 (3) , pp. 255-262. 10.1016/j.jinf.2012.10.008

Paixao Cavalcante, Danielle, López-Trascasa, Margarita, Skattum, Lillemor, Giclas, Patricia C, Goodship, Timothy H, de Córdoba, Santiago Rodríguez, Truedsson, Lennart, Morgan, Bryan Paul

and Harris, Claire Louise 2012. Sensitive and specific assays for C3 nephritic factors clarify mechanisms underlying complement dysregulation. Kidney International 82 (10) , pp. 1084-1092. 10.1038/ki.2012.250

Goodship, Timothy H.J., Pappworth, Isabel Y., Toth, Tibor, Denton, Mark, Houlberg, Kris, McCormick, Frances, Warland, David, Moore, Iain, Hunze, Eva-Maria, Staniforth, Scott J., Hayes, Christine, Cavalcante, Danielle Paixão, Kavanagh, David, Strain, Lisa, Herbert, Andrew P., Schmidt, Christoph Q., Barlow, Paul N., Harris, Claire Louise and Marchbank, Kevin J. 2012. Factor H autoantibodies in membranoproliferative glomerulonephritis. Molecular Immunology 52 (3-4) , pp. 200-206. 10.1016/j.molimm.2012.05.009

Harris, Claire Louise, Heurich, Meike

, Rodriguez de Cordoba, Santiago and Morgan, Bryan Paul

2012. The complotype: dictating risk for inflammation and infection. Trends in Immunology 33 (10) , pp. 513-521. 10.1016/j.it.2012.06.001

Ingram, Gillian, Hakobyan, Svetlana, Hirst, Claire Louise, Harris, Claire Louise, Loveless, Samantha

, Mitchell, John Paul, Pickersgill, Trevor, Robertson, Neil

and Morgan, Bryan Paul

2012. Systemic complement profiling in multiple sclerosis as a biomarker of disease state. Multiple Sclerosis Journal 18 (10) , pp. 1401-1411. 10.1177/1352458512438238

Kempshall, Emma, Thebault, Simon, Morgan, Bryan Paul

, Harris, Claire Louise and Gallimore, Awen Myfanwy

2012. Complement-induced protection: an explanation for the limitations of cell-based tumour immunotherapies. Immunology and Cell Biology 90 (9) , pp. 869-871. 10.1038/icb.2012.30

Brown, J. H., Tellez, J., Wilson, V., Mackie, I. J., Scully, M., Tredger, M. M., Moore, I., McDougall, N. I., Strain, L., Marchbank, K. J., Sheerin, N. S., O'Grady, J., Harris, Claire Louise and Goodship, T. H. J. 2012. Postpartum aHUS secondary to a genetic abnormality in factor H acquired through liver transplantation. American Journal of Transplantation 12 (6) , pp. 1632-1636. 10.1111/j.1600-6143.2012.03991.x

Mizuno, Masashi, Ito, Yasuhiko, Mizuno, Tomohiro, Harris, Claire Louise, Suzuki, Yasuhiro, Okada, Noriko, Matsuo, Seiichi and Morgan, Bryan Paul

2012. Membrane complement regulators protect against fibrin exudation increases in a severe peritoneal inflammation model in rats. American Journal of Physiology-Renal Physiology 302 (10) , F1245-F1251. 10.1152/ajprenal.00652.2011

Francis, Nigel

, McNicholas, Bairbre, Awan, Atif, Waldron, Mary, Reddan, Donal, Sadlier, Denise, Kavanagh, David, Strain, Lisa, Marchbank, Kevin J., Harris, Claire Louise and Goodship, Timothy H. J. 2012. A novel hybrid CFH/CFHR3 gene generated by a microhomology-mediated deletion in familial atypical hemolytic uremic syndrome. Blood 119 (2) , pp. 591-601. 10.1182/blood-2011-03-339903

Gibson, J., Hakobyan, Svetlana, Cree, A. J., Collins, A., Harris, Claire Louise, Ennis, S., Morgan, Bryan Paul

and Lotery, A. J. 2012. Variation in complement component C1 inhibitor in age-related macular degeneration. Immunobiology 217 (2) , pp. 251-255. 10.1016/j.imbio.2011.07.015

de Córdoba, Santiago Rodríguez, Harris, Claire Louise, Morgan, Bryan Paul

and Llorca, Oscar 2011. Lessons from functional and structural analyses of disease-associated genetic variants in the complement alternative pathway. Biochimica et Biophysica Acta - Molecular Basis of Disease 1812 (1) , pp. 12-22. 10.1016/j.bbadis.2010.09.002

Roversi, Pietro, Johnson, Steven, Caesar, Joseph J. E., McLean, Florence, Leath, Kirstin J., Tsiftsoglou, Stefanos A., Morgan, Bryan Paul

, Harris, Claire Louise, Sim, Robert B. and Lea, Susan M. 2011. Structures of the rat complement regulator CrrY. Acta Crystallographica Section F: Structural Biology and Crystallization Communications 67 (7) , pp. 739-743. 10.1107/S1744309111016551

Smith, Richard J. H., Harris, Claire Louise and Pickering, Matthew C. 2011. Dense deposit disease. Molecular Immunology 48 (14) , pp. 1604-1610. 10.1016/j.molimm.2011.04.005

Pechtl, I. C., Kavanagh, D., Mcintosh, N., Harris, Claire Louise and Barlow, P. N. 2011. Disease-associated N-terminal Complement Factor H Mutations Perturb Cofactor and Decay-accelerating Activities. Journal of Biological Chemistry 286 (13) , pp. 11082-11090. 10.1074/jbc.M110.211839

Alcorlo, M., Martínez-Barricarte, R., Fernández, F. J., Rodríguez-Gallego, C., Round, A., Vega, M. C., Harris, Claire Louise, Rodríguez de Cordoba, S. and Llorca, O. 2011. Correction for Alcorlo et al., Unique structure of iC3b resolved at a resolution of 24 A by 3D-electron microscopy [Correction]. Proceedings of the National Academy of Sciences 108 (39) , p. 16481. 10.1073/pnas.1112875108

Alcorlo, M., Martinez-Barricarte, R., Fernandez, F. J., Rodriguez-Gallego, C., Round, A., Vega, M. C., Harris, Claire Louise, de Cordoba, S. R. and Llorca, O. 2011. Unique structure of iC3b resolved at a resolution of 24 Å by 3D-electron microscopy. Proceedings of the National Academy of Sciences of the United States of America 108 (32) , pp. 13236-13240. 10.1073/pnas.1106746108

Roversi, P., Johnson, S., Caesar, J. J. E., McLean, F., Leath, K. J., Tsiftsoglou, S. A., Morgan, Bryan Paul

, Harris, Claire Louise, Sim, R. B. and Lea, S. M. 2011. Structural basis for complement factor I control and its disease-associated sequence polymorphisms. Proceedings of the National Academy of Sciences of the United States of America 108 (31) , pp. 12839-12844. 10.1073/pnas.1102167108

Heurich, Meike

, Martinez-Barricarte, Ruben, Francis, Nigel

, Roberts, Dawn L., Rodriguez de Cordoba, Santiago, Morgan, Bryan Paul

and Harris, Claire Louise 2011. Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk. Proceedings of the National Academy of Sciences of the United States of America 108 (21) , pp. 8761-8766. 10.1073/pnas.1019338108

Martínez-Barricarte, Rubén, Heurich, Meike

, Valdes-Cañedo, Francisco, Vazquez-Martul, Eduardo, Torreira, Eva, Montes, Tamara, Tortajada, Agustín, Pinto, Sheila, Lopez-Trascasa, Margarita, Morgan, Bryan Paul

, Llorca, Oscar, Harris, Claire Louise and Rodríguez de Córdoba, Santiago 2010. Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation. Journal of Clinical Investigation 120 (10) , pp. 3702-3712. 10.1172/JCI43343

Ingram, Gillian, Hakobyan, Svetlana, Hirst, Claire Louise, Harris, Claire Louise, Pickersgill, Trevor, Cossburn, Mark D., Loveless, Samantha

, Robertson, Neil

and Morgan, Bryan Paul

2010. Complement regulator factor H as a serum biomarker of multiple sclerosis disease state. Brain 133 (6) , pp. 1602-1611. 10.1093/brain/awq085

Manickam, Balasubramanian, Jha, Purushottam, Hepburn, Natalie Jayne, Morgan, Bryan Paul

, Harris, Claire Louise, Bora, Puran S. and Bora, Nalini S. 2010. Suppression of complement activation by recombinant Crry inhibits experimental autoimmune anterior uveitis (EAAU). Molecular Immunology 48 (1-3) , pp. 231-239. 10.1016/j.molimm.2010.08.006

Hakobyan, Svetlana, Tortajada, Agustín, Harris, Claire Louise, de Córdoba, Santiago R and Morgan, Bryan Paul

2010. Variant-specific quantification of factor H in plasma identifies null alleles associated with atypical hemolytic uremic syndrome. Kidney International 78 (8) , pp. 782-788. 10.1038/ki.2010.275

Tortajada, Agustin, Montes, Tamara, Martinez-Barricarte, Ruben, Morgan, Bryan Paul

, Harris, Claire Louise and de Cordoba, Santiago Rodriguez 2009. The disease-protective complement factor H allotypic variant Ile62 shows increased binding affinity for C3b and enhanced cofactor activity. Human Molecular Genetics 18 (18) , pp. 3452-3461. 10.1093/hmg/ddp289

Hughes, Timothy Richard

, Ross, Kirsty S., Cowan, Graeme J. M., Baalasubramanian, Sivasank, Harris, Claire Louise, Mitchell, Timothy J. and Morgan, Bryan Paul

2009. Identification of the high affinity binding site in the Streptococcus intermedius toxin intermedilysin for its membrane receptor, the human complement regulator CD59. Molecular Immunology 46 (7) , pp. 1561-1567. 10.1016/j.molimm.2009.01.003

Montes, Tamara, Tortajada, Agustin, Morgan, Bryan Paul

, Rodriguez de Cordoba, Santiago and Harris, Claire Louise 2009. Functional basis of protection against age-related macular degeneration conferred by a common polymorphism in complement factor B. Proceedings of the National Academy of Sciences 106 (11) , pp. 4366-4371. 10.1073/pnas.0812584106

Ruseva, Marieta Milkova, Hughes, Timothy Richard

, Donev, Rossen Mintchev, Baalasubramanian, Sivasankar, Pickering, Matthew C., Wu, Xiaobo, Harris, Claire Louise and Morgan, Bryan Paul

2009. Crry deficiency in complement sufficient mice: C3 consumption occurs without associated renal injury. Molecular Immunology 46 (5) , pp. 803-811. 10.1016/j.molimm.2008.09.003

Kolev, Martin

, Ruseva, Marieta Milkova, Harris, Claire Louise, Morgan, Bryan Paul

and Donev, Rossen Mintchev 2009. Implication of complement system and its regulators in Alzheimer's Disease. Current Neuropharmacology 7 (1) , pp. 1-8.

Mizuno, Masashi, Ito, Yasuhiko, Hepburn, Natalie Jayne, Mizuno, Tomohiro, Noda, Yukihiro, Yuzawa, Yukio, Harris, Claire Louise, Morgan, Bryan Paul

and Matsuo, Seiichi 2009. Zymosan, but not lipopolysaccharide, triggers severe and progressive peritoneal injury accompanied by complement activation in a rat peritonitis model. The Journal of Immunology 183 (2) , pp. 1403-1412. 10.4049/jimmunol.0804245

Kolev, Martin

, Tediose, Teeo, Baalasubramanian, Sivasankar, Harris, Claire Louise, Thome, J., Morgan, Bryan Paul

and Donev, Rossen Mintchev 2009. Upregulating CD59: a new strategy for protection of neurons from complement-mediated degeneration. The Pharmacogenomics Journal 10 (1) , pp. 12-19. 10.1038/tpj.2009.52

Hakobyan, Svetlana, Harris, Claire Louise, Van Den Berg, Carmen Wilma, Fernandez-Alonso, Maria Carmen, de Jorge, Elena Goicoechea, de Cordoba, Santiago Rodriguez, Rivas, German, Mangione, Palma, Pepys, Mark B. and Morgan, Bryan Paul

2008. Complement factor H binds to denatured rather than to native pentameric C-reactive protein. Journal of Biological Chemistry 283 (45) , pp. 30451-30460. 10.1074/jbc.M803648200

Hepburn, Natalie Jayne, Ruseva, Marieta Milkova, Harris, Claire Louise and Morgan, Bryan Paul

2008. Complement, roles in renal disease and modulation for therapy. Clinical Nephrology 70 (5) , pp. 357-376.

Hepburn, Natalie Jayne, Chamberlain-Banoub, Jayne L., Williams, Anwen Sian

, Morgan, Bryan Paul

and Harris, Claire Louise 2008. Prevention of experimental autoimmune myasthenia gravis by rat Crry-Ig: a model agent for long-term complement inhibition in vivo. Molecular Immunology 45 (2) , pp. 395-405. 10.1016/j.molimm.2007.06.144

Hakobyan, Svetlana, Harris, Claire Louise, Tortajada, Agustín, Goicochea de Jorge, Elena, Garcia-Layana, Alfredo, Fernandez-Robredo, Patricia, Rodriguez de Cordoba, Santiago and Morgan, Bryan Paul

2008. Measurement of factor H variants in plasma using variant-specific monoclonal antibodies: application to assessing risk of age-related macular degeneration. Investigative Ophthalmology and Visual Science 49 (5) , pp. 1983-1990. 10.1167/iovs.07-1523

Hepburn, Natalie Jayne, Williams, Anwen Sian

, Morgan, Bryan Paul

and Harris, Claire Louise 2007. In Vivo Characterization and Therapeutic Efficacy of a C5-specific Inhibitor from the Soft Tick Ornithodoros moubata. J Biol Chem 282 , pp. 8292-8299. 10.1074/jbc.M609858200

Harris, Claire Louise, Cordoba, S. Rodriguez de, Jorge, E. Goicoechea de and Morgan, Bryan Paul

2007. Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome. Proceedings of the National Academy of Sciences 104 (1) , pp. 240-5. 10.1073/pnas.0603420103

Harris, Claire Louise, Morgan, Bryan Paul

, Pettigrew, D.M. and Lea, S.M. 2007. Decay-accelerating factor must bind both components of the complement alternative pathway c3 convertase to mediate efficient decay. Journal of Immunology 178 , pp. 352-359.

Hepburn, Natalie J., Williams, Anwen Sian

, Chamberlain, Jayne C., Hamer, Joseph, Nunn, M. A., Morgan, Bryan Paul

and Harris, Claire Louise 2007. In vivo characterisation and therapeutic efficacy of a C5-specific inhibitor [Abstract]. Molecular Immunology 44 (1-3) , p. 183. 10.1016/j.molimm.2006.07.087

Mizuno, Masashi, Donev, Rossen Mark, Harris, Claire Louise and Morgan, Bryan Paul

2007. CD55 in rat male reproductive tissue: Differential expression in testis and expression of a unique truncated isoform on spermatozoa. Molecular Immunology 44 (7) , pp. 1613-1622. 10.1016/j.molimm.2006.08.018

Harris, Claire Louise, Morgan, Bryan Paul

, Lea, S. M. and Abbott, R. J. 2005. Molecular dissection of interactions between components of the alternative pathway of complement and decay accelerating factor (CD55). Journal of Biological Chemistry 280 (4) , pp. 2569-78. 10.1074/jbc.M410179200

Baalasubramanian, Sivasankar, Harris, Claire Louise, Donev, Rossen Mintchev, Mizuno, Masashi, Omidvar, Nader, Song, Wen-Chao and Morgan, Bryan Paul

2004. CD59a is the primary regulator of membrane attack complex assembly in the mouse. Journal of Immunology 173 , pp. 3684-3692.

Harris, Claire Louise and Morgan, Bryan

2004. The many faces of the membrane regulators of complement. Szebeni, Janos, ed. The Complement System: Novel Roles in Health and Disease, Boston: Kluwer, pp. 129-166.

Sivasankar, B., Mizuno, Masashi, Donev, Rossen Mintchev, Omidvar, Nader, Harris, Claire Louise, Song, W. C. and Morgan, Bryan Paul

2004. CD59b is expressed at low level on mouse erythrocytes and has a negligible protective role in the presence of CD59a. Molecular Immunology 41 (2-3) , pp. 307-308. 10.1016/j.molimm.2004.03.002

Williams, Anwen Sian

, Fraser, D. A., Harris, Claire Louise and Mizuno, Masashi 2003. Generation of a recombinant, membrane-targeted form of the complement regulator CD59: activity in vitro and in vivo. The Journal of Biological Chemistry 278 (49) , pp. 48921-48927. 10.1074/jbc.M302598200

Harris, Claire Louise, Hughes, Clare Elizabeth

, Williams, Anwen Sian

, Goodfellow, Ian, Evans, David J., Caterson, Bruce

and Morgan, Bryan Paul

2003. Generation of anti-complement 'prodrugs': cleavable reagents for specific delivery of complement regulators to disease sites. The Journal of Biological Chemistry 278 (38) , pp. 36068-36076. 10.1074/jbc.M306351200

Clayton, Aled

, Harris, Claire Louise, Morgan, Bryan Paul

and Mason, Malcolm David

2003. Antigen-presenting cell exosomes are protected from complement-mediated lysis by expression of CD55 and CD59. European Journal of Immunology 33 (2) , pp. 522-31. 10.1002/immu.200310028

Labeta, Mario Oscar

, Nores, J. E. Rey, Vigar, Miriam Ann and Harris, Claire Louise 2001. The lipopolysaccharide co-receptor CD14 is present and functional in seminal plasma and expressed on spermatozoa. Immunology 104 (3) , pp. 317-23. 10.1046/j.1365-2567.2001.01312.x

Harris, Claire Louise 2000. Functional assays for complement regulators. Morgan, B. P., ed. Complement Methods and Protocols, Methods in Molecular Biology, Totowa, NJ: Humana Press, pp. 83-103.

This list was generated on Sat Oct 25 11:07:38 2025 BST.