Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Browse by Current Cardiff authors

Number of items: 46.

Alshahrany, Nawal, Begum, Ayesha, Siebzehnrubl, Dorit, Jimenez-Pascual, Ana and Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775 2023. Spatial distribution and functional relevance of FGFR1 and FGFR2 expression for glioblastoma tumor invasion. Cancer Letters 571 , 216349. 10.1016/j.canlet.2023.216349
file

Singh, Niharika, Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775 and Martinez Garay, Isabel ORCID: https://orcid.org/0000-0001-6849-7496 2023. Transcriptional control of embryonic and adult neural progenitor activity. Frontiers in Neuroscience 17 , 1217596. 10.3389/fnins.2023.1217596
file

Bates, Emily A., Lovatt, Charlotte, Plein, Alice R., Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2023. Engineering adenoviral vectors with improved GBM selectivity. Viruses 15 (5) , 1086. 10.3390/v15051086
file

Brown, J.M.C., Zaben, M. ORCID: https://orcid.org/0000-0002-7446-4532, Ormonde, C., Sharouf, F. ORCID: https://orcid.org/0000-0002-3034-3392, Spencer, R., Bhatt, H., Siebzehnrubl, F.A. ORCID: https://orcid.org/0000-0001-8411-8775 and Gray, W.P. ORCID: https://orcid.org/0000-0001-7595-8887 2023. A high-density 3-dimensional culture model of human glioblastoma for rapid screening of therapeutic resistance. Biochemical Pharmacology 208 , 115410. 10.1016/j.bcp.2023.115410
file

Petrik, David ORCID: https://orcid.org/0000-0003-3026-0770, Jorgensen, Sara, Eftychidis, Vasileios and Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775 2022. Singular adult neural stem cells do not exist. Cells 11 (4) , 722. 10.3390/cells11040722
file

Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775 2022. Isolating and culturing of precursor cells from the adult human brain. Deleyrolle, Loic P., ed. Neural Progenitor Cells: Methods and Protocols, Vol. 2389. Methods in Molecular Biology, New York, NY: Springer, pp. 95-102. (10.1007/978-1-0716-1783-0_9)

Gupta, Bhavana, Errington, Adam C. ORCID: https://orcid.org/0000-0002-2171-389X, Jimenez-Pascual, Ana, Eftychidis, Vasileios, Brabletz, Simone, Stemmler, Marc P., Brabletz, Thomas, Petrik, David ORCID: https://orcid.org/0000-0003-3026-0770 and Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775 2021. The transcription factor ZEB1 regulates stem cell self-renewal and cell fate in the adult hippocampus. Cell Reports 36 (8) , 109588. 10.1016/j.celrep.2021.109588
file

Pope, Iestyn ORCID: https://orcid.org/0000-0002-4104-0389, Masia, Francesco ORCID: https://orcid.org/0000-0003-4958-410X, Ewan, Kenneth ORCID: https://orcid.org/0000-0001-6622-9009, Jimenez-Pascual, Ana, Dale, Trevor C. ORCID: https://orcid.org/0000-0002-4880-9963, Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775, Borri, Paola ORCID: https://orcid.org/0000-0002-7873-3314 and Langbein, Wolfgang ORCID: https://orcid.org/0000-0001-9786-1023 2021. Identifying subpopulations in multicellular systems by quantitative chemical imaging using label-free hyperspectral CARS microscopy. Analyst 146 (7) , pp. 2277-2291. 10.1039/D0AN02381G
file

Almotiri, Alhomidi, Alzahrani, Hamed Ahmad A., Menendez-Gonzalez, Juan Bautista, Abdelfattah, Ali, Alotaibi, Badi, Saleh, Lubaid, Greene, Adelle, Georgiou, Mia R. F., Gibbs, Alex, Alsayari, Amani Salem, Taha, Sarab, Thomas, Leigh-Anne, Shah, Dhruv, Edkins, Sarah ORCID: https://orcid.org/0000-0003-0717-1972, Giles, Peter J. ORCID: https://orcid.org/0000-0003-3143-6854, Stemmler, Marc P., Brabletz, Simone, Brabletz, Thomas, Boyd, Ashleigh S., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775 and Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733 2021. Zeb1 modulates hematopoietic stem cell fates required for suppressing acute myeloid leukemia. Journal of Clinical Investigation 131 (1) , e129115. 10.1172/JCI129115
file

Badr, Christian E., Silver, Daniel J., Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775 and Deleyrolle, Loic P. 2020. Metabolic heterogeneity and adaptability in brain tumors. Cellular and Molecular Life Sciences 77 , pp. 5101-5119. 10.1007/s00018-020-03569-w
file

Scholz, Nico, Kurian, Kathreena M., Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775 and Licchesi, Julien D. F. 2020. Targeting the ubiquitin system in glioblastoma. Frontiers in Oncology 10 , 574011. 10.3389/fonc.2020.574011
file

Jimenez-Pascual, Ana, Mitchell, Kelly, Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775 and Lathia, Justin D. 2020. FGF2: a novel druggable target for glioblastoma? Expert Opinion on Therapeutic Targets 24 (4) , pp. 311-318. 10.1080/14728222.2020.1736558
file

Jimenez-Pascual, Ana, Hale, James S., Kordowski, Anja, Pugh, Jamie, Silver, Daniel J., Bayik, Defne, Roversi, Gustavo, Alban, Tyler J., Rao, Shilpa, Chen, Rui, McIntyre, Thomas M., Colombo, Giorgio, Taraboletti, Giulia, Holmberg, Karl O., Forsberg-Nilsson, Karin, Lathia, Justin D. and Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775 2019. ADAMDEC1 maintains a growth factor signaling loop in cancer stem cells. Cancer Discovery 9 (11) , pp. 1574-1589. 10.1158/2159-8290.CD-18-1308
filefilefilefilefilefilefile

Jimenez-Pascual, Ana, Lathia, Justin D. and Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775 2019. ADAMDEC1 and FGF2/FGFR1 signaling constitute a positive feedback loop to maintain GBM cancer stem cells. Molecular & Cellular Oncology 7 (1) , 1684787. 10.1080/23723556.2019.1684787
file

Jimenez-Pascual, Ana and Siebzehnrubl, Florian A ORCID: https://orcid.org/0000-0001-8411-8775 2019. Fibroblast growth factor receptor functions in glioblastoma. Cells 8 (7) , 715. 10.3390/cells8070715
file

Hoang-Minh, Lan B., Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775, Yang, Changlin, Suzuki-Hatano, Silveli, Dajac, Kyle, Loche, Tyler, Andrews, Nicholas, Massari, Michael Schmoll, Patel, Jaimin, Amin, Krisha, Vuong, Alvin, Jimenez Pascual, Ana, Kubilis, Paul, Garrett, Timothy J., Moneypenny, Craig, Pacak, Christina A., Huang, Jianping, Sayour, Elias J., Mitchell, Duane A., Sarkisian, Matthew R., Reynolds, Brent . and Deleyrolle, Loic P. 2018. Infiltrative and drug-resistant slow-cycling cells support metabolic heterogeneity in glioblastoma. EMBO Journal 37 (23) , e98772. 10.15252/embj.201798772
filefile

Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775, Raber, Kerstin A., Urbach, Yvonne K., Schulze-Krebs, Anja, Canneva, Fabio, Moceri, Sandra, Habermeyer, Johanna, Achoui, Dalila, Gupta, Bhavana, Steindler, Dennis A., Stephan, Michael, Nguyen, Huu Phuc, Bonin, Michael, Riess, Olaf, Bauer, Andreas, Aigner, Ludwig, Couillard-Despres, Sebastien, Paucar, Martin Arce, Svenningsson, Per, Osmand, Alexander, Andreew, Alexander, Zabel, Claus, Weiss, Andreas, Kuhn, Rainer, Moussaoui, Saliha, Blockx, Ines, Van der Linden, Annemie, Cheong, Rachel Y., Roybon, Laurent, Petersén, Åsa and von Hörsten, Stephan 2018. Early postnatal behavioral, cellular, and molecular changes in models of Huntington disease are reversible by HDAC inhibition. Proceedings of the National Academy of Sciences 115 (37) , E8765-E8774. 10.1073/pnas.1807962115
file

Roy, Ananya, Attarha, Sanaz, Weishaupt, Holger, Edqvist, Per-Henrik, Swartling, Fredrik J., Bergqvist, Michael, Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Smits, Anja, Pontén, Fredrik and Tchougounova, Elena 2017. Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression. Oncotarget 8 , pp. 24815-24827. 10.18632/oncotarget.15820
file

Kahlert, Ulf D., Suwala, Abigail K., Raabe, Eric H., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Suarez, Maria J., Orr, Brent A., Bar, Eli E., Maciaczyk, Jaroslaw and Eberhart, Charles G. 2015. ZEB1 promotes invasion in human fetal neural stem cells and hypoxic glioma neurospheres. Brain Pathology 25 (6) , pp. 724-732. 10.1111/bpa.12240

Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775 2015. Application of an RNA amplification method for reliable single-cell transcriptome analysis. Biotechniques 59 (3) , pp. 137-148. 10.2144/000114331

Vedam-Mai, Vinata, Gardner, Bronwen, Okun, Michael S., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Kam, Monica, Aponso, Palingu, Steindler, Dennis A., Yachnis, Anthony T., Neal, Dan, Oliver, Brittany U., Rath, Sean J., Faull, Richard L. M., Reynolds, Brent A. and Curtis, Maurice A. 2014. Increased precursor cell proliferation after deep brain stimulation for Parkinson's disease: a human study. PLoS ONE 9 (3) , e88770. 10.1371/journal.pone.0088770
file

Sarkisian, Matthew R., Siebzehnrubl, Dorit, Hoang-Minh, Lan, Deleyrolle, Loic, Silver, Daniel J., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Guadiana, Sarah M., Srivinasan, Gayathri, Semple-Rowland, Susan, Harrison, Jeffrey K., Steindler, Dennis A. and Reynolds, Brent A. 2014. Detection of primary cilia in human glioblastoma. Journal of Neuro-Oncology 117 (1) , pp. 15-24. 10.1007/s11060-013-1340-y

Silver, Daniel J., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Schildts, Michela J., Yachnis, Anthony T., Smith, George M., Smith, Amy A., Scheffler, Bjorn, Reynolds, Brent A., Silver, Jerry and Steindler, Dennis A. 2013. Chondroitin Sulfate Proteoglycans Potently Inhibit Invasion and Serve as a Central Organizer of the Brain Tumor Microenvironment. Journal of Neuroscience 33 (39) , pp. 15603-15617. 10.1523/JNEUROSCI.3004-12.2013

Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Silver, Daniel J., Tugertimur, Bugra, Deleyrolle, Loic P., Siebzehnrubl, Dorit, Sarkisian, Matthew R., Devers, Kelly G., Yachnis, Antony T., Kupper, Marius D., Neal, Daniel, Nabilsi, Nancy H., Kladde, Michael P., Suslov, Oleg, Brabletz, Simone, Brabletz, Thomas, Reynolds, Brent A. and Steindler, Dennis A. 2013. The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance. EMBO Molecular Medicine 5 (8) , pp. 1196-1212. 10.1002/emmm.201302827

Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775 and Steindler, Dennis A. 2013. Isolating and culturing of precursor cells from the adult human brain. Reynolds, Brent A. and Delerolle, Loic P., eds. Neural Progenitor Cells, Vol. 1059. Methods in Molecular Biology, Springer, pp. 79-86. (10.1007/978-1-62703-574-3_7)

Wang, Shanshan, Okun, Michael S., Suslov, Oleg, Zheng, Tong, McFarland, Nikolaus R., Vedam-Mai, Vinata, Foote, Kelly D., Roper, Steven N., Yachnis, Anthony T., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775 and Steindlera, Dennis A. 2012. Neurogenic potential of progenitor cells isolated from postmortem human Parkinsonian brains. Brain Research 1464 , pp. 61-72. 10.1016/j.brainres.2012.04.039

Steffenhagen, Carolin, Kraus, Sabrina, Dechant, Franz-Xaver, Kandasamy, Mahesh, Lehner, Bernadette, Poehler, Anne-Maria, Furtner, Tanja, Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Couillard-Despres, Sebastien, Strauss, Olaf, Aigner, Ludwig and Rivera, Francisco J. 2011. Identity, fate and potential of cells grown as neurospheres: species matters. Stem Cell Reviews and Reports 7 (4) , pp. 815-835. 10.1007/s12015-011-9251-9

Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Reynolds, B. A., Vescovi, A., Steindler, D. A. and Deleyrolle, L. P. 2011. The origins of glioma: E pluribus unum? GLIA 59 (8) , pp. 1135-1147. 10.1002/glia.21143

Deleyrolle, Loic P., Harding, Angus, Cato, Kathleen, Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Rahman, Maryam, Azari, Hassan, Olson, Sarah, Gabrielli, Brian, Osborne, Geoffrey, Vescovi, Angelo and Reynolds, Brent A. 2011. Evidence for label-retaining tumour-initiating cells in human glioblastoma. Brain 134 , pp. 1331-1343. 10.1093/brain/awr081

Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Vedam-Mai, Vinata, Azari, Hassan, Reynolds, Brent A. and Deleyrolle, Loic P. 2011. Isolation and characterization of adult neural stem cells. Filippi, Marie-Dominique and Geiger, Hartmut, eds. Stem Cell Migration, Vol. 750. Methods in Molecular Biology, Springer, pp. 61-77. (10.1007/978-1-61779-145-1_4)

Coras, Roland, Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Pauli, Elisabeth, Huttner, Hagen B., Njunting, Marleisje, Kobow, Katja, Villmann, Carmen, Hahnen, Eric, Neuhuber, Winfried, Weigel, Daniel, Buchfelder, Michael, Stefan, Hermann, Beck, Heinz, Steindler, Dennis A. and Bluemcke, Ingmar 2010. Low proliferation and differentiation capacities of adult hippocampal stem cells correlate with memory dysfunction in humans. Brain 133 (11) , pp. 3359-3372. 10.1093/brain/awq215

Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Jeske, Ina, Mueller, Dorit, Buslei, Rolf, Coras, Roland, Hahnen, Eric, Huttner, Hagen B., Corbeil, Denis, Kaesbauer, Johanna, Appl, Thomas, von Hoersten, Stephan and Bluemcke, Ingmar 2009. Spontaneous in vitro transformation of adult neural precursors into stem-like cancer cells. Brain Pathology 19 (3) , pp. 399-408. 10.1111/j.1750-3639.2008.00189.x

Weiss, S., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Kreutzer, J., Bluemcke, I. and Buslei, R. 2009. Evidence for a progenitor cell population in the human pituitary. Clinical Neuropathology 28 (4) , pp. 309-318.

Rivera, Francisco J., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Kandasamy, Mahesh, Couillard-Despres, Sebastien, Caioni, Massimiliano, Poehler, Anne-Maria, Berninger, Benedikt, Sandner, Beatrice, Bogdahn, Ulrich, Goetz, Magdalena, Bluemcke, Ingmar, Weidner, Norbert and Aigner, Ludwig 2009. Mesenchymal stem cells promote oligodendroglial differentiation in hippocampal slice cultures. Cellular Physiology and Biochemistry 24 (3-4) , pp. 317-324. 10.1159/000233256

Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775 and Blumcke, Ingmar 2008. Neurogenesis in the human hippocampus and its relevance to temporal lobe epilepsies. Epilepsia 49 (s5) , pp. 55-65. 10.1111/j.1528-1167.2008.01638.x

Huttner, Hagen B., Janich, Peggy, Koehrmann, Martin, Jaszai, Jozsef, Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Bluemcke, Ingmar, Suttorp, Meinolf, Gahr, Manfred, Kuhnt, Daniela, Nimsky, Christopher, Krex, Dietmar, Schackert, Gabriele, Loewenbrueck, Kai, Reichmann, Heinz, Juettler, Eric, Hacke, Werner, Schellinger, Peter D., Schwab, Stefan, Wilsch-Braeuninger, Michaela, Marzesco, Anne-Marie and Corbeil, Denis 2008. The stem cell marker prominin-1/CD133 on membrane particles in human cerebrospinal fluid offers novel approaches for studying central nervous system disease. Stem Cells 26 (3) , pp. 698-705. 10.1634/stemcells.2007-0639

Coras, Roland, Hoelsken, Annett, Seufert, Sebastian, Hauke, Jan, Eyuepoglu, Ilker Y., Reichel, Martin, Traenkle, Christian, Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Buslei, Rolf, Bluemcke, Ingmar and Hahnen, Eric 2007. The peroxisome proliferator-activated receptor-gamma agonist troglitazone inhibits transforming growth factor-beta-mediated glioma cell migration and brain invasion. Molecular Cancer Therapeutics 6 (6) , pp. 1745-1754. 10.1158/1535-7163.MCT-06-0763

Buslei, Rolf, Hoelsken, Annett, Hofmann, Bernd, Kreutzer, Juergen, Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Hans, Volkmar, Oppel, Falk, Buchfelder, Michael, Fahlbusch, Rudolf and Bluemcke, Ingmar 2007. Nuclear beta-catenin accumulation associates with epithelial morphogenesis in craniopharyngiomas. Acta Neuropathologica 113 (5) , pp. 585-590.

Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Buslei, Rolf, Eyupoglu, Ilker Y., Seufert, Sebastian, Hahnen, Eric and Blumcke, Ingmar 2007. Histone deacetylase inhibitors increase neuronal differentiation in adult forebrain precursor cells. Experimental Brain Research 176 (4) , pp. 672-678. 10.1007/s00221-006-0831-x

Hoelsken, Annett, Eyuepoglu, Ilker Y., Lueders, Mike, Traenkle, Christian, Dieckmann, Detlef, Buslei, Rolf, Hahnen, Eric, Bluemcke, Ingmar and Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775 2006. Ex vivo therapy of malignant melanomas transplanted into organotypic brain slice cultures using inhibitors of histone deacetylases. Acta Neuropathologica 112 (2) , pp. 205-215. 10.1007/s00401-006-0082-8

Hahnen, E., Eyupoglu, I. Y., Brichta, L., Haastert, K., Trankle, C., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Riessland, M., Holker, I., Claus, P., Romstock, J., Buslei, R., Wirth, B. and Blumcke, I. 2006. In vitro and ex vivo evaluation of second-generation histone deacetylase inhibitors for the treatment of spinal muscular atrophy. Journal of Neurochemistry 98 (1) , pp. 193-202. 10.1111/j.1471-4159.2006.03868.x

Buslei, R., Kreutzer, J., Hofmann, B., Schmidt, V., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Hahnen, E., Eyupoglu, I. Y., Fahlbusch, R. and Blumcke, I. 2006. Abundant hypermethylation of SOCS-1 in clinically silent pituitary adenomas. Acta Neuropathologica 111 (3) , pp. 264-271. 10.1007/s00401-005-0009-9

Eyupoglu, I. Y., Hahnen, E., Tränkle, C., Savaskan, N. E., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Buslei, R., Lemke, D., Wick, W., Fahlbusch, R. and Blümcke, I. 2006. Experimental therapy of malignant gliomas using the inhibitor of histone deacetylase MS-275. Molecular Cancer Therapeutics 5 (5) , p. 1248. 10.1158/1535-7163.MCT-05-0533

Buslei, R., Nolde, M., Hofmann, B., Meissner, S., Eyupoglu, I. Y., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Hahnen, E., Kreutzer, J. and Fahlbusch, R. 2005. Common mutations of beta-catenin in adamantinomatous craniopharyngiomas but not in other tumours originating from the sellar region. Acta Neuropathologica 109 (6) , pp. 589-597.

Eyupoglu, I. Y., Hahnen, E., Buslei, R., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Savaskan, N. E., Luders, M., Trankle, C., Wick, W., Weller, M., Fahlbusch, R. and Blumcke, I. 2005. Suberoylanilide hydroxamic acid (SAHA) has potent anti-glioma properties in vitro, ex vivo and in vivo. Journal of Neurochemistry 93 (4) , pp. 992-999. 10.1111/j.1471-4159.2005.03098.x

Eyupoglu, I. Y., Hahnen, E., Heckel, A., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Buslei, R., Fahlbusch, R. and Blumcke, I. 2005. Malignant glioma-induced neuronal cell death in an organotypic glioma invasion model. Technical note. Journal of Neurosurgery 102 (4) , pp. 738-744. 10.3171/jns.2005.102.4.0738

This list was generated on Sat Nov 23 09:10:02 2024 GMT.