Burnell, Stephanie E. A., Capitani, Lorenzo, MacLachlan, Bruce J., Mason, Georgina H., Gallimore, Awen M. and Godkin, Andrew
2021.
Seven mysteries of LAG-3: a multi-faceted immune receptor of increasing complexity.
Immunotherapy Advances
2
(1)
, ltab025.
10.1093/immadv/ltab025
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MacLachlan, Bruce J., Mason, Georgina H., Greenshields Watson, Alexander, Triebel, Frederic, Gallimore, Awen, Cole, David K. and Godkin, Andrew
2021.
Molecular characterization of HLA class II binding to the LAG-3 T cell co-inhibitory receptor.
European Journal of Immunology
51
(2)
, pp. 331-341.
10.1002/eji.202048753
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Greenshields-Watson, Alexander, Attaf, Meriem, MacLachlan, Bruce J., Whalley, Thomas, Rius, Cristina, Wall, Aaron, Lloyd, Angharad, Hughes, Hywel, Strange, Kathryn E., Mason, Georgina H., Schauenburg, Andrea J., Hulin-Curtis, Sarah L., Geary, James, Chen, Yuan, Lauder, Sarah N., Smart, Kathryn, Vijaykrishna, Dhanasekaran, Grau, Miguel L., Shugay, Mikhail, Andrews, Robert, Dolton, Garry, Rizkallah, Pierre J., Gallimore, Awen M., Godkin, Andrew J., Sewell, Andrew J. and Cole, David K.
2020.
CD4 + T cells recognize conserved influenza A epitopes through shared patterns of V-Gene usage and complementary biochemical features.
Cell Reports
32
(2)
, 107885.
10.1016/j.celrep.2020.107885
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Besneux, Matthieu, Greenshields Watson, Alexander, Scurr, Martin, MacLachlan, Bruce J., Christian, Adam, Davies, Michael M., Hargest, Rachel, Phillips, Simon, Godkin, Andrew and Gallimore, Awen
2019.
The nature of the human T cell response to the cancer antigen 5T4 is determined by the balance of regulatory and inflammatory T cells of the same antigen-specificity: implications for vaccine design.
Cancer Immunology, Immunotherapy
68
, pp. 247-256.
10.1007/s00262-018-2266-1
![]() |
|
Holland, Christopher J., MacLachlan, Bruce J., Bianchi, Valentina, Hesketh, Sophie J., Morgan, Richard, Vickery, Owen, Bulek, Anna M., Fuller, Anna, Godkin, Andrew, Sewell, Andrew K., Rizkallah, Pierre J., Wells, Stephen and Cole, David K. 2018. In silico and structural analyses demonstrate that intrinsic protein motions guide T cell receptor complementarity determining region loop flexibility. Frontiers in Immunology 9 , 674. 10.3389/fimmu.2018.00674 |
|
MacLachlan, Bruce J., Greenshields-Watson, Alexander, Mason, Georgina H., Schauenburg, Andrea J., Bianchi, Valentina, Rizkallah, Pierre J., Sewell, Andrew K., Fuller, Anna and Cole, David K.
2017.
Using X-ray crystallography, biophysics, and functional assays to determine the mechanisms governing T-cell receptor recognition of cancer antigens.
Journal of Visualized Experiments
(120)
, e54991.
10.3791/54991
![]() |
|
MacLachlan, Bruce James
2016.
Molecular characterisation of CD4+ T cell responses to tumour antigens.
PhD Thesis,
Cardiff University.
Item availability restricted. |
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