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Number of items: 21.

Greenshields-Watson, Alexander, Attaf, Meriem, MacLachlan, Bruce J., Whalley, Thomas, Rius, Cristina ORCID: https://orcid.org/0000-0002-1896-1649, Wall, Aaron, Lloyd, Angharad, Hughes, Hywel, Strange, Kathryn E., Mason, Georgina H., Schauenburg, Andrea J., Hulin-Curtis, Sarah L. ORCID: https://orcid.org/0000-0003-0889-964X, Geary, James, Chen, Yuan, Lauder, Sarah N., Smart, Kathryn, Vijaykrishna, Dhanasekaran, Grau, Miguel L., Shugay, Mikhail, Andrews, Robert, Dolton, Garry, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Gallimore, Awen M. ORCID: https://orcid.org/0000-0001-6675-7004, Godkin, Andrew J. ORCID: https://orcid.org/0000-0002-1910-7567, Sewell, Andrew J. ORCID: https://orcid.org/0000-0003-3194-3135 and Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396 2020. CD4 + T cells recognize conserved influenza A epitopes through shared patterns of V-Gene usage and complementary biochemical features. Cell Reports 32 (2) , 107885. 10.1016/j.celrep.2020.107885
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MacLachlan, Bruce J., Dolton, Garry, Papakyriakou, Athanasios, Greenshields-Watson, Alexander, Mason, Georgina H., Schauenburg, Andrea, Besneux, Matthieu, Szomolay, Barbara ORCID: https://orcid.org/0000-0002-5375-5533, Elliott, Tim, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2019. Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope. Journal of Biological Chemistry 294 (52) , pp. 20246-20258. 10.1074/jbc.RA119.009437
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Madura, Florian, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Legut, Mateusz, Holland, Christopher J., Fuller, Anna, Bulek, Anna, Schauenburg, Andrea J., Trimby, Andrew, Hopkins, Jade R., Wells, Stephen A., Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567, Miles, John J., Sami, Malkit, Li, Yi, Liddy, Nathaniel, Jakobsen, Bent K., Loveridge, E. Joel, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2019. TCR-induced alteration of primary MHC peptide anchor residue. European Journal of Immunology 49 (7) , pp. 1052-1066. 10.1002/eji.201948085
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Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Fuller, Anna, Dolton, Garry, Zervoudi, Efthalia, Legut, Mateusz, Miles, Kim, Blanchfield, Lori, Madura, Florian, Holland, Christopher J., Bulek, Anna M., Bridgeman, John S., Miles, John J., Schauenburg, Andrea J. A., Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Evavold, Brian D., Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2017. Dual molecular mechanisms govern escape at immunodominant HLA A2-restricted HIV epitope. Frontiers in Immunology 8 , 1503. 10.3389/fimmu.2017.01503
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Jones, Nicholas, Cronin, James G., Dolton, Garry, Panetti, Silvia, Schauenburg, Andrea, Galloway, Sarah A. E., Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Thornton, Catherine A. and Francis, Nigel J. ORCID: https://orcid.org/0000-0002-4706-4795 2017. Metabolic adaptation of human CD4+ and CD8+ T-Cells to T-Cell receptor-mediated stimulation. Frontiers in Immunology 8 , 1516. 10.3389/fimmu.2017.01516
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MacLachlan, Bruce J., Greenshields-Watson, Alexander, Mason, Georgina H., Schauenburg, Andrea J., Bianchi, Valentina, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Fuller, Anna and Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396 2017. Using X-ray crystallography, biophysics, and functional assays to determine the mechanisms governing T-cell receptor recognition of cancer antigens. Journal of Visualized Experiments (120) , e54991. 10.3791/54991
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Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, van den Berg, Hugo A., Lloyd, Angharad, Crowther, Michael D., Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Ekeruche-Makinde, Julia, Miles, John J., Bulek, Anna M., Dolton, Garry, Schauenburg, Andrea J., Wall, Aaron, Fuller, Anna, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Laugel, Bruno, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Wooldridge, Linda and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2017. Structural mechanism underpinning cross-reactivity of a CD8+ T-cell clone that recognises a peptide derived from human telomerase reverse transcriptase. Journal of Biological Chemistry 292 (3) , pp. 802-813. 10.1074/jbc.M116.741603
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Szomolay, Barbara ORCID: https://orcid.org/0000-0002-5375-5533, Liu, Jie, Brown, Paul E., Miles, John J., Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Llewellyn-Lacey, Sian, Dolton, Garry, Ekeruche-Makinde, Julia, Lissina, Anya, Schauenburg, Andrea J., Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Burrows, Scott R., Roederer, Mario, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Wooldridge, Linda and van den Berg, Hugo A. 2016. Identification of human viral protein-derived ligands recognized by individual MHCI-restricted T-cell receptors. Immunology and Cell Biology 94 (6) , pp. 573-582. 10.1038/icb.2016.12
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Schauenburg, Andrea J. A. 2016. Molecular mechanisms underlying pMHC-II recognition. PhD Thesis, Cardiff University.
Item availability restricted.
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Holland, Christopher J., Dolton, Garry M., Scurr, Martin ORCID: https://orcid.org/0000-0002-4120-0688, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Schauenburg, Andrea J., Miners, Kelly, Madura, Florian, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396 and Godkin, Andrew J. ORCID: https://orcid.org/0000-0002-1910-7567 2015. Enhanced detection of antigen-specific CD4+ T cells using altered peptide flanking residue peptide-MHC class II multimers. Journal of Immunology 195 (12) , pp. 5827-5836. 10.4049/jimmunol.1402787
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Neller, Michelle A., Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, McLaren, James Edward ORCID: https://orcid.org/0000-0002-7021-5934, Matthews, Katherine K., Gostick, Emma, Pentier, Johanne, Dolton, Garry Michael, Schauenburg, Andrea J. A., Koning, Dan, Fontaine Costa, Ana Isabel C. A., Watkins, Thomas S., Venturi, Vanessa, Smith, Corey, Khanna, Rajiv, Miners, Kelly Louise, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Wooldridge, Linda, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, van Baarle, Debbie, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Burrows, Scott R., Price, David ORCID: https://orcid.org/0000-0001-9416-2737 and Miles, John James 2015. Naive CD8+ T-cell precursors display structured TCR repertoires and composite antigen-driven selection dynamics. Immunology and Cell Biology 93 , pp. 625-633. 10.1038/icb.2015.17
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Madura, Florian, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Holland, Christopher J., Fuller, Anna, Bulek, Anna Marta, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Schauenburg, Andrea J., Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2015. Structural basis for ineffective T-cell responses to MHC anchor residue-improved 'heteroclitic' peptides. European Journal of Immunology 45 (2) , pp. 584-591. 10.1002/eji.201445114
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Tungatt, Katie, Bianchi, Valentina, Crowther, Michael D., Powell, Wendy ORCID: https://orcid.org/0000-0002-4670-1406, Schauenburg, Andrea J. A., Trimby, Andrew R., Donia, M., Miles, John James, Holland, Christopher J., Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Peakman, M., Straten, P. T., Svane, I. M., Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 and Dolton, Garry Michael 2015. Antibody stabilization of peptide-MHC multimers reveals functional T cells bearing extremely low-affinity TCRs. Journal of Immunology 194 (1) , pp. 463-474. 10.4049/jimmunol.1401785
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Kløverpris, Henrik N., Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Fuller, Anna, Carlson, Jonathan, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Schauenburg, Andrea J. A., Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Buus, Søren, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 and Goulder, Philip 2015. A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape. Retrovirology 12 (1) , 20. 10.1186/s12977-015-0149-5
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Madura, Florian, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Miles, Kim Michelle, Holland, Christopher J., Bulek, Anna Marta, Fuller, Anna, Schauenburg, Andrea J. A., Miles, John James, Liddy, Nathaniel, Sami, M., Li, Y., Hossain, M., Baker, B. M., Jakobsen, B. K., Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 and Cole, David ORCID: https://orcid.org/0000-0003-0028-9396 2013. T-cell receptor specificity maintained by altered thermodynamics. Journal of Biological Chemistry 288 (26) , pp. 18766-18775. 10.1074/jbc.M113.464560

Eukeruche-Makinde, Julia, Miles, John J., Van Den Berg, Hugo A., Skowera, Ania, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Dolton, Garry Michael, Schauenburg, Andrea, Tan, Mai Ping, Pentier, Johanne, Llewellyn-Lacey, Sian, Miles, Kim M., Bulek, Anna, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Dockree, Tamsin, Trimby, Andrew R., Bailey, Mick, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Rossjohn, Jamie ORCID: https://orcid.org/0000-0002-2020-7522, Peakman, Mark, Burrows, Scott, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 and Wooldridge, Linda 2013. Peptide length determines the outcome of TCR/peptide-MHCI engagement. Blood -New York- 121 (7) , pp. 1112-1123. 10.1182/blood-2012-06-437202

Ekeruche, Julia, Miles, John James, van den Berg, Hugo A., Skowera, Ania, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Dolton, Garry Michael, Schauenburg, Andrea J. A., Tan, Mai Ping, Pentier, Johanne, Llewellyn-Lacey, Sian, Miles, Kim Michelle, Bulek, Anna Marta, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Williams, Tamsin, Trimby, Andrew R., Bailey, Mick, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Rossjohn, Jamie ORCID: https://orcid.org/0000-0002-2020-7522, Peakman, Mark, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Burrows, Scott R., Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 and Wooldridge, Linda 2013. Peptide length determines the outcome of TCR/peptide-MHCI engagement. Blood 121 (7) , pp. 1112-1123. 10.1182/blood-2012-06-437202

Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Miles, Kim Michelle, Madura, Florian, Holland, Christopher J., Schauenburg, Andrea J. A., Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Bulek, Anna Marta, Fuller, Anna, Akpovwa, Hephzibah, Pymm, Phillip G., Liddy, N., Sami, M., Li, Y., Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Jakobsen, B. K. and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2013. T-cell Receptor (TCR)-Peptide Specificity Overrides Affinity-enhancing TCR-Major Histocompatibility Complex Interactions. Journal of Biological Chemistry 289 (2) , pp. 628-638. 10.1074/jbc.M113.522110
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Bulek, Anna Marta, Madura, Florian, Fuller, Anna, Holland, Christopher J., Schauenburg, Andrea J. A., Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369 and Cole, David ORCID: https://orcid.org/0000-0003-0028-9396 2012. TCR/pMHC optimized protein crystallization screen. Journal of Immunological Methods 382 (1-2) , pp. 203-210. 10.1016/j.jim.2012.06.007

Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Ekeruche, Julia, Miles, John James, Edwards, Emily ORCID: https://orcid.org/0000-0002-0240-4370, Dolton, Garry Michael, Williams, Tamsin, Schauenburg, Andrea J. A., Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Lauder, Sarah Nicol, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Burrows, Scott R., Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 and Wooldridge, Linda 2011. Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining. The Journal of Immunology 187 (2) , pp. 654-663. 10.4049/jimmunol.1003941

Miles, John James, Bulek, Anna Marta, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Gostick, Emma, Schauenburg, Andrea J. A., Dolton, Garry Michael, Venturi, Vanessa, Davenport, Miles P., Tan, Mai Ping, Burrows, Scott R., Wooldridge, Linda, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2010. Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection. PLoS Pathogens 6 (11) , e1001198. 10.1371/journal.ppat.1001198
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This list was generated on Mon Nov 18 09:00:57 2024 GMT.


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