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Telomere dynamics in human health and disease.
Cold Spring Harbor Perspectives in Biology
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Cleal, Kez, Kearsey, Alexander and Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467
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GW: ultra-fast chromosome-scale visualization of genomics data.
Nature Methods
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Adam, Nancy, Yang, Yang, Djamshidi, Mahbod, Seifan, Sara, Ting, Nicholas S. Y., Glover, Joel, Touret, Nicolas, Gordon, Paul M. K., Vineetha Warriyar, K. V., Krowicki, Hokan, Garcia, Christine Kim, Savage, Sharon A., Goodarzi, Aaron A., Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467, Beattie, Tara L. and Riabowol, Karl
2025.
hTERT Increases TRF2 to induce telomere compaction and extend cell replicative lifespan.
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Pazhakh, Vahid, Fox, Lucy C., Den Elzen, Nicole, Emerson, Matthew R., Cohen, Scott B., Bryan, Tracy M., Norris, Kevin, Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467, Cochrane, Tara, Mackintosh, John, Scott, Ashleigh and Blombery, Piers
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A novel TERT variant associated with a telomere biology disorder and challenges in variant classification.
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Myers, Kasiani C., Davies, Stella M., Lutzko, Carolyn, Wahle, Robin, Grier, David D., Aubert, Geraldine, Norris, Kevin, Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467, Koga, Minako, Ko, Akihiro C., Amano, Tomokazu, Amano, Misa, Yu, Hong and Ko, Minoru S.H.
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Clinical use of ZSCAN4 for telomere elongation in hematopoietic stem cells.
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Louise, Carr, Norris, Kevin, Helen, Parker, Anna, Nilsson-Takeuchi, Dean, Bryant, Harindra, Amarasinghe, Latha, Kadalayil, Monica, Else, Andrew, Pettitt, Peter, Hillmen, Anna, Schuh, Renata, Walewska, Baird, Duncan ORCID: https://orcid.org/0000-0001-8408-5467, G., Oscier David, C., Oakes Christopher, Jane, Gibson, Pepper, Christopher and C., Strefford Jonathan
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Letter to the Editor: Telomere length and DNA methylation epitype both provide independent prognostic information in CLL patients; data from the UK CLL, ARCTIC and ADMIRE clinical trials.
British Journal of Haematology
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Hulme, Charlotte H., Garcia, John K., Mennan, Claire, Perry, Jade, Roberts, Sally, Norris, Kevin, Baird, Duncan ORCID: https://orcid.org/0000-0001-8408-5467, Rix, Larissa, Banerjee, Robin, Meyer, Carl and Wright, Karina T.
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The upscale manufacture of chondrocytes for allogeneic cartilage therapies.
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Roger, Laureline, Miners, Kelly L., Leonard, Louise, Grimstead, Julia W., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467 and Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938
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T cell memory revisited using single telomere length analysis.
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Aquilanti, Elisa, Kageler, Lauren, Watson, Jacqueline, Baird, Duncan M ORCID: https://orcid.org/0000-0001-8408-5467, Jones, Rhiannon E, Hodges, Marie, Szegletes, Zsofia M, Doench, John G, Strathdee, Craig A, McFaline Figueroa, Jose Ricardo, Ligon, Keith, Beck, Matthew, Wen, Patrick Y and Meyerson, Matthew
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Telomerase inhibition is an effective therapeutic strategy in TERT promoter mutant-glioblastoma models with low tumor volume.
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Liddiard, Kate ORCID: https://orcid.org/0000-0002-0953-1997, Aston-Evans, Alys N., Cleal, Kez, Hendrickson, Eric A. and Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467
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POLQ suppresses genome instability and alterations in DNA repeat tract lengths.
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Parker, Christopher, Chambers, Adam C., Flanagan, Dustin J., Ho, Jasmine Wing Yu, Collard, Tracey J., Ngo, Greg, Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467, Timms, Penny, Morgan, Rhys G., Sansom, Owen J. and Williams, Ann C.
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BCL-3 loss sensitises colorectal cancer cells to DNA damage by targeting homologous recombination.
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Cleal, Kez and Baird, Duncan ORCID: https://orcid.org/0000-0001-8408-5467
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Dysgu: efficient structural variant calling using short or long reads.
Nucleic Acids Research
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Pepper, Andrea G. S., Zucchetto, Antonella, Norris, Kevin, Tissino, Erika, Polesel, Jerry, Soe, Zarni, Allsup, David, Hockaday, Anna, Ow, Pei Loo, Hillmen, Peter, Rawstron, Andrew, Catovsky, Daniel, Bulian, Pietro, Bomben, Riccardo, Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467, Fegan, Christopher D. ORCID: https://orcid.org/0000-0001-9685-0621, Gattei, Valter and Pepper, Chris
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Combined analysis of IGHV mutations, telomere length and CD49d identifies long-term progression-free survivors in TP53 wild-type CLL treated with FCR-based therapies.
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ATRX modulates the escape from a telomere crisis.
Plos Genetics
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Garcia Martin, Isabel, Penketh, Richard J. A., Garay, Samantha M., Jones, Rhiannon E., Grimstead, Julia W., Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467 and John, Rosalind M. ORCID: https://orcid.org/0000-0002-3827-7617
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Symptoms of prenatal depression associated with shorter telomeres in female placenta.
International Journal of Molecular Sciences
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Norris, Kevin, Walne, Amanda J., Ponsford, Mark J., Cleal, Kez, Grimstead, Julia, Ellison, Alicia, Alnajar, Jenna, Dokal, Inderjeet and Baird, Duncan ORCID: https://orcid.org/0000-0001-8408-5467
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High-throughput STELA provides a rapid test for the diagnosis of telomere biology disorders.
Human Genetics
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Telomere length in Cystic Fibrosis patients - are patients with CF ageing too quickly?
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Galletti, Giovanni, De Simone, Gabriele, Mazza, Emilia M.C., Puccio, Simone, Mezzanotte, Claudia, Bi, Timothy M., Davydov, Alexey N., Metsger, Maria, Scamardella, Eloise, Alvisi, Giorgia, Paoli, Federica De, Zanon, Veronica, Scarpa, Alice, Camisa, Barbara, Colombo, Federico S., Anselmo, Achile, Peano, Clelia, Polletti, Sara, Mavilio, Domenico, Gattinoni, Luca, Boi, Shannon K., Youngblood, Benjamin A., Jones, Rhiannon E., Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467, Gostick, Emma, Llewellyn-Lacey, Sian, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Chudakov, Dmitriy M., Newell, Evan W., Casucci, Monica and Lugli, Enrico
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Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans.
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CD57+ Memory T Cells Proliferate In Vivo.
Cell Reports
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Adishesh, Meera, Alnafakh, Rafah, Baird, Duncan ORCID: https://orcid.org/0000-0001-8408-5467, Jones, Rhiannon E., Simon, Shannon, Button, Lucy, Kamal, Areege, Kirwan, John, DeCruze, S. Bridget, Drury, Josephine, Saretzki, Gabriele and Hapangama, Dharani K.
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Human endometrial carcinogenesis is associated with significant reduction in long non-coding RNA, TERRA.
International Journal of Molecular Sciences
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Cleal, Kez and Baird, Duncan ORCID: https://orcid.org/0000-0001-8408-5467
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Catastrophic endgames: emerging mechanisms of telomere-driven genomic instability.
Trends in Genetics
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Harrington, Lea and Baird, Duncan ORCID: https://orcid.org/0000-0001-8408-5467
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Editorial overview: the instability of the cancer genome: it starts at the end.
Current Opinion in Genetics and Development
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Kwok, Marwan, Oldreive, Ceri, Rawstron, Andy C., Goel, Anshita, Papatzikas, Grigorios, Jones, Rhiannon E., Drennan, Samantha, Agathanggelou, Angelo, Sharma-Oates, Archana, Evans, Paul, Smith, Edward, Dalal, Surita, Mao, Jingwen, Hollows, Robert, Gordon, Naheema, Hamada, Mayumi, Davies, Nicholas J, Parry, Helen, Beggs, Andrew D., Munir, Talha, Moreton, Paul, Paneesha, Shankara, Pratt, Guy, Taylor, A. Malcolm R., Forconi, Francesco, Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467, Cazier, Jean-Baptiste, Moss, Paul, Hillmen, Peter and Stankovic, Tatjana
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Integrative analysis of spontaneous CLL regression highlights genetic and microenvironmental interdependency in CLL.
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Telomere length predicts for outcome to FCR chemotherapy in CLL.
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Cleal, Kez, Jones, Rhiannon E., Grimstead, Julia W., Hendrickson, Eric A. and Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467
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Chromothripsis during telomere crisis is independent of NHEJ, and consistent with a replicative origin.
Genome Research
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DNA Ligase 1 is an essential mediator of sister chromatid telomere fusions in G2 cell cycle phase.
Nucleic Acids Research
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Mansell, Els, Zareian, Nahid, Malouf, Camille, Kapeni, Chrysa, Brown, Natalie, Badie, Christophe, Baird, Duncan ORCID: https://orcid.org/0000-0001-8408-5467, Lane, Jon, Ottersbach, Katrin, Blair, Allison and Case, Charles Patrick
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DNA damage signalling from the placenta to foetal blood as a potential mechanism for
childhood leukaemia initiation.
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Pringle, Sarah, Wang, Xiaoyang, Verstappen, Gwenny M.P.J., Terpstra, Jannek, Zhang, Clarence K., He, Aiqing, Patel, Vishal, Jones, Rhiannon E., Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467, Spijkervet, Fred K. L., Vissink, Arjan, Bootsma, Hendrika, Coppes, Robert P. and Kroese, Frans G.M.
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Salivary gland stem cells age prematurely in primary Sjögren's syndrome.
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Ngo, Greg, Hyatt, Sam, Grimstead, Julia, Jones, Rhiannon, Hendrickson, Eric, Pepper, Chris and Baird, Duncan ORCID: https://orcid.org/0000-0001-8408-5467
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PARP inhibition prevents escape from a telomere-driven crisis and inhibits cell immortalisation.
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Meformin and insulin treatment prevent placental telomere attrition in boys exposed to maternal diabetes.
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PARP1 is required for preserving telomeric integrity but is dispensable for A-NHEJ.
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Telomeres and Chromosomal Translocations.
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Human TSCM cell dynamics in vivo are compatible with long-lived immunological memory and stemness.
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Nelson, Nya D., Dodson, Lois M., Escudero-Monreal, Laura, Sukumar, Ann T., Williams, Christopher L., Mihalek, Ivana, Baldan, Alessandro, Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467 and Bertuch, Alison A.
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The C-terminal extension unique to the long isoform of the shelterin component TIN2 enhances its interaction with TRF2 in a phosphorylation- and dyskeratosis congenita-cluster-dependent fashion.
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Telomeres and genomic evolution.
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CCR8 expression defines tissue-resident memory T cells in human skin.
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Pilsworth, Jessica A., Cochrane, Dawn R., XIa, Zhouchunyang, Aubert, Geraldine, Farkilla, Anniina E. M., Horlings, Hugo M., Yanagida, Satoshi, Yang, Winnie, Lim, Jamie L. P., Wang, Yi Kan, Bashashati, Ali, Keul, Jacqueline, Wong, Adele, Norris, Kevin, Brucker, Sara Y., Taran, Florin-Andrei, Kramer, Bernhard, Staebler, Annette, Olivia, Esther, Shah, Sohrab P., Kommoss, Stefan, Kommoss, Friedrich, Gilks, C. Blake, Baird, Duncan ORCID: https://orcid.org/0000-0001-8408-5467 and Huntsman, David G.
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TERT promoter mutation in adult granulosa cell tumor of the ovary.
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Cleal, Kez, Norris, Kevin and Baird, Duncan ORCID: https://orcid.org/0000-0001-8408-5467
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Telomere length dynamics and the evolution of cancer genome architecture.
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Telomere length heterogeneity in placenta revealed with high-resolution telomere length analysis.
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Telomere length is a critical determinant for survival in multiple myeloma.
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Williams, Jenna, Heppel, Nicole, Britt-Compton, Bethan, Grimstead, Julia, Robinson, Rhiannon, Tauro, Sudhir, Bowen, David, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Groves, Michael, Hills, Robert ORCID: https://orcid.org/0000-0003-0166-0062, Pepper, Christopher J., Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467 and Fegan, Christopher D. ORCID: https://orcid.org/0000-0001-9685-0621
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Telomere length is an independent prognostic marker in MDS but not in de novo AML.
British Journal of Haematology
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Lopez Anton, Melisa, Rudolf, Andras, Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Roger, Laureline, Robinson, Rhiannon, Witowski, Janusz, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435
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Telomere length profiles in primary human peritoneal mesothelial cells are consistent with senescence.
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Rice, Cory, Shastrula, Prashanth Krishna, Kossenkov, Andrew V., Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Showe, Louise C., Doukov, Tzanko, Janicki, Susan and Skordalakes, Emmanuel
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Structural and functional analysis of the human POT1-TPP1 telomeric complex.
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Robinson, Rhiannon, Grimstead, Julia, Sedani, Ashni, Baird, Duncan ORCID: https://orcid.org/0000-0001-8408-5467 and Upadhyaya, Meena
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Telomere erosion in NF1 tumorigenesis.
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Letsolo, Boitelo, Robinson, Rhiannon, Rowson, Jan, Grimstead, Julia, Keith, Nicol, Jenkins, Gareth and Baird, Duncan MArtin ORCID: https://orcid.org/0000-0001-8408-5467
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Extensive telomere erosion is consistent with localised clonal expansions in Barrett's metaplasia.
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Fellows, Christopher R., Williams, Rebecca, Davies, Iwan R,, Gohil, Kajal, Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467, Fairclough, John, Rooney, Paul, Archer, Charles W. and Khan, Ilyas M.
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Characterisation of a divergent
progenitor cell sub-populations
in human osteoarthritic cartilage:
the role of telomere erosion and
replicative senescence.
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Ahmed, Raya, Roger, Laureline, Costa del Amo, Pedro, Miners, Kelly L., Jones, Rhiannon E., Boelen, Lies, Fali, Tinhinane, Elemans, Marjet, Zhang, Yan, Appay, Victor, Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467, Asquith, Becca, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Macallan, Derek C. and Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938
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Human stem cell-like memory T cells are maintained in a state of dynamic flux.
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Nelson, David M., Jaber-Hijazi, Farah, Cole, John J., Robertson, Neil A., Pawlikowski, Jeffrey S., Norris, Kevin T., Criscione, Steven W., Pchelintsev, Nikolay A., Piscitello, Desiree, Stong, Nicholas, Rai, Taranjit Singh, McBryan, Tony, Otte, Gabriel L., Nixon, Colin, Clark, William, Riethman, Harold, Wu, Hong, Schotta, Gunnar, Garcia, Benjamin A., Neretti, Nicola, Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467, Berger, Shelley L. and Adams, Peter D.
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Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability.
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|
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Liddiard, Kate ORCID: https://orcid.org/0000-0002-0953-1997, Ruis, Brian, Takasugi, Taylor, Harvey, Adam, Ashelford, Kevin E. ORCID: https://orcid.org/0000-0003-3217-2811, Hendrickson, Eric A. and Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467
2016.
Sister chromatid telomere fusions, but not NHEJ-mediated inter-chromosomal telomere fusions, occur independently of DNA ligases 3 and 4.
Genome Research
26
, pp. 588-600.
10.1101/gr.200840.115
|
|
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Strefford, J. C., Kadalayil, L., Forster, J., Rose-Zerilli, M. J. J., Parker, A., Lin, T. T., Heppel, N., Norris, K., Gardiner, A., Davies, Z., Gonzalez de Castro, D., Else, M., Steele, A . J., Parker, H., Stankovic, T., Pepper, C., Fegan, C., Baird, D. ORCID: https://orcid.org/0000-0001-8408-5467, Collins, A., Catovsky, D. and Oscier, D. G.
2015.
Telomere length predicts progression and overall survival in chronic lymphocytic leukemia: data from the UK LRF CLL4 trial.
Leukemia
29
(12)
, pp. 2411-2414.
10.1038/leu.2015.217
|
|
Martin-Ruiz, C. M., Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Roger, Laureline, Boukamp, P., Krunic, D., Cawthon, R., Dokter, M. M., van der Harst, P., Bekaert, S., de Meyer, T., Roos, G., Svenson, U., Codd, V., Samani, N. J., McGlynn, L., Shiels, P. G., Pooley, K. A., Dunning, A. M., Cooper, R., Wong, A., Kingston, A. and von Zglinicki, T.
2015.
Reproducibility of telomere length assessment: an international collaborative study.
International Journal of Epidemiology
44
(5)
, pp. 1673-1683.
10.1093/ije/dyu191
|
|
|
Martin-Ruiz, Carmen M, Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Roger, Laureline, Boukamp, Petra, Krunic, Damir, Cawthon, Richard, Dokter, Martin M, Van Der Harst, Pim, Bekaert, Sofie, De Meyer, Tim, Roos, Goran, Svenson, Ulrika, Codd, Veryan, Samani, Nilesh J, Mcglynn, Liane, Shiels, Paul G, Pooley, Karen A, Dunning, Alison M, Cooper, Rachel, Wong, Andrew, Kingston, Andrew and Von Zglinicki, Thomas
2015.
Reproducibility of telomere length assessment: Authors’ response to Damjan Krstajic and Ljubomir Buturovic.
International Journal of Epidemiology
44
(5)
, pp. 1739-1741.
10.1093/ije/dyv170
|
|
Martin-Ruiz, Carmen M, Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Roger, Laureline, Boukamp, Petra, Krunic, Damir, Cawthon, Richard, Dokter, Martin M, Van Der Harst, Pim, Bekaert, Sofie, De Meyer, Tim, Roos, Goran, Svenson, Ulrika, Codd, Veryan, Samani, Nilesh J, Mcglynn, Liane, Shiels, Paul G, Pooley, Karen A, Dunning, Alison M, Cooper, Rachel, Wong, Andrew, Kingston, Andrew and Von Zglinicki, Thomas
2015.
Is Southern blotting necessary to measure telomere length reproducibly? Authors? Response to: Commentary: The reliability of telomere length measurements.
International Journal of Epidemiology
44
(5)
, pp. 1686-1687.
10.1093/ije/dyv169
|
|
Simpson, Katherine, Jones, R. E., Grimstead, Julia W., Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Pepper, Christopher John and Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467
2015.
Telomere fusion threshold identifies a poor prognostic subset of breast cancer patients.
Molecular Oncology
9
(6)
, pp. 1186-1193.
10.1016/j.molonc.2015.02.003
|
|
|
Lin, Thet Thet, Norris, Kevin, Heppel, Nicole H., Pratt, Guy, Allan, James M., Allsup, David J., Bailey, James, Cawkwell, Lynn, Hills, Robert ORCID: https://orcid.org/0000-0003-0166-0062, Grimstead, Julia W., Jones, Rhiannon E., Britt-Compton, Bethan, Fegan, Christopher ORCID: https://orcid.org/0000-0001-9685-0621, Baird, Duncan Matrin ORCID: https://orcid.org/0000-0001-8408-5467 and Pepper, Christopher
2014.
Telomere dysfunction accurately predicts clinical outcome in chronic lymphocytic leukaemia, even in patients with early stage disease.
British Journal of Haematology
167
(2)
, pp. 214-223.
10.1111/bjh.13023
|
|
Jones, Rhiannon E., Oh, Sehyun, Grimstead, Julia W., Zimbric, Jacob, Roger, Laureline, Heppel, Nicole H., Ashelford, Kevin E. ORCID: https://orcid.org/0000-0003-3217-2811, Liddiard, Kate ORCID: https://orcid.org/0000-0002-0953-1997, Hendrickson, Eric A. and Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467
2014.
Escape from telomere-driven crisis is DNA Ligase III dependent.
Cell Reports
8
(4)
, pp. 1063-1076.
10.1016/j.celrep.2014.07.007
|
|
Nussey, Daniel H., Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Barrett, Emma, Boner, Winnie, Fairlie, Jennifer, Gemmell, Neil, Hartmann, Nils, Horn, Thorsten, Haussmann, Mark, Olsson, Mats, Turbill, Chris, Verhulst, Simon, Zahn, Sandrine, Monaghan, Pat and Leder, Erica
2014.
Measuring telomere length and telomere dynamics in evolutionary biology and ecology.
Methods in Ecology and Evolution
5
(4)
, pp. 299-310.
10.1111/2041-210X.12161
|
|
Singh, Umashankar, Maturi, Varun, Jones, Rhiannon, Paulsson, Ylva, Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467 and Westermark, Bengt
2013.
CGGBP1 phosphorylation constitutes a telomere-protection signal.
Cell Cycle
13
(1)
, pp. 96-105.
10.4161/cc.26813
|
|
Roger, Laureline, Jones, Rhiannon E., Heppel, Nicole, Williams, Geraint Trefor ORCID: https://orcid.org/0000-0003-3768-9940, Sampson, Julian Roy ORCID: https://orcid.org/0000-0002-2902-2348 and Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467
2013.
Extensive telomere erosion in the initiation of colorectal adenomas and its association with chromosomal instability.
Journal of the National Cancer Institute
105
(16)
, pp. 1202-1211.
10.1093/jnci/djt191
|
|
Pettigrew, Kerry A., Armstrong, Richard N., Colyer, Hilary A. A., Zhang, Shu-Dong, Rea, Irene Maeve, Robinson, Rhiannon Elizabeth, Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467 and Mills, Ken I.
2012.
Differential tert promoter methylation and
response to 5-aza-20-deoxycytidine in Acute Myeloid
Leukemia cell lines: tert expression, telomerase
activity, telomere length, and cell death.
Genes, Chromosomes and Cancer
51
(8)
, pp. 768-780.
10.1002/gcc.21962
|
|
Britt-Compton, Bethan, Lin, Thet Thet, Ahmed, G., Weston, V., Robinson, Rhiannon Elizabeth, Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621, Oscier, D. G., Stankovic, T., Pepper, Christopher John and Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467
2012.
Extreme telomere erosion in ATM-mutated and 11q-deleted CLL patients is independent of disease stage [Letter].
Leukemia
26
(4)
, pp. 826-830.
10.1038/leu.2011.281
|
|
Mocellin, Simone, Verdi, Daunia, Pooley, Karen A., Landi, Maria T., Egan, Kathleen M., Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Prescott, Jennifer, De Vivo, Immaculata and Nitti, Donato
2012.
Telomerase reverse transcriptase locus polymorphisms and cancer risk: A field synopsis and meta-analysis.
Journal of the National Cancer Institute
104
(11)
, pp. 840-854.
10.1093/jnci/djs222
|
|
Tankimanova, Maira, Capper, Rebecca, Letsolo, Boitelo Theresiah, Rowson, Janet Maud, Robinson, Rhiannon, Britt-Compton, Bethan, Taylor, A. Malcolm R. and Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467
2012.
Mre11 modulates the fidelity of fusion between short telomeres in human cells.
Nucleic Acids Research
40
(6)
, pp. 2518-2526.
10.1093/nar/gkr1117
|
|
Jones, Ceri H., Pepper, Christopher John and Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467
2012.
Telomere dysfunction and its role in haematological cancer.
British Journal of Haematology
156
(5)
, pp. 573-587.
10.1111/j.1365-2141.2011.09022.x
|
|
Sood, A., Salih, S., Roh, D., Lacharme-Lora, L., Parry, M., Hardiman, B., Keehan, R., Grummer, R., Winterhager, E., Gokhale, P. J., Andrews, P. W., Abbott, C., Forbes, K., Westwood, M., Aplin, J. D., Ingham, E., Papageorgiou, I., Berry, M., Liu, J., Dick, A. D., Garland, R. J., Williams, N., Singh, R., Simon, A. K., Lewis, Mark David, Ham, Jack, Roger, Laureline, Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Crompton, L. A., Caldwell, M. A., Swalwell, H., Birch-Machin, M., Lopez-Castejon, G., Randall, A., Lin, H., Suleiman, M-S., Evans, William Howard, Newson, R. and Case, C. P.
2011.
Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness.
Nature Nanotechnology
6
(12)
, pp. 824-833.
10.1038/nnano.2011.188
|
|
Svenson, Ulrika, Nordfjäll, Katarina, Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Roger, Laureline, Osterman, Pia, Hellenius, Mai-Lis and Roos, Göran
2011.
Blood cell telomere length is a dynamic feature.
PLoS ONE
6
(6)
, e21485.
10.1371/journal.pone.0021485
|
|
Pepper, Christopher John and Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467
2010.
Shortened telomeres: a driving force behind leukemia? [Editorial].
Future Oncology
6
(11)
, pp. 1681-1686.
10.2217/fon.10.135
|
|
Takubo, Kaiyo, Aida, Junko, Izumiyama, Naotaka, Ishikawa, Naoshi, Fujiwara, Mutsunori, Poon, Steven S. S., Kondo, Hiroshi, Kammori, Makoto, Matsuura, Masaaki, Sawabe, Motoji, Arai, Tomio, Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467 and Nakamura, Ken-Ichi
2010.
Chromosomal instability and telomere lengths of each chromosomal arm measured by Q-FISH in human fibroblast strains prior to replicative senescence.
Mechanisms of Ageing and Development
131
(10)
, pp. 614-624.
10.1016/j.mad.2010.08.007
|
|
Williams, Rebecca ORCID: https://orcid.org/0000-0003-2168-7369, Khan, Ilyas Mahmood, Richardson, Kirsty, Nelson, Larissa, McCarthy, Helen Elizabeth, Analbelsi, Talsal, Singhrao, Simarjit Kaur, Dowthwaite, Gary Paul, Robinson, Rhiannon Elizabeth, Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Lewis, Holly, Roberts, Selwyn, Shaw, Hannah M., Dudhia, Jayesh, Fairclough, John, Briggs, Timothy and Archer, Charles William
2010.
Identification and clonal characterisation of a progenitor cell sub-population in normal human articular cartilage.
PLoS ONE
5
(10)
, e13246.
10.1371/journal.pone.0013246
|
|
|
Lin, Thet Thet, Letsolo, Boitelo Theresiah, Robinson, Rhiannon Elizabeth, Rowson, Janet Maud, Pratt, Guy, Hewamana, Saman, Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621, Pepper, Christopher John and Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467
2010.
Telomere dysfunction and fusion during the progression of chronic lymphocytic leukemia: evidence for a telomere crisis.
Blood
116
(11)
, pp. 1899-1907.
10.1182/blood-2010-02-272104
|
|
Letsolo, Boitelo Theresiah, Rowson, Janet Maud and Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467
2010.
Fusion of short telomeres in human cells is characterized by extensive deletion and microhomology, and can result in complex rearrangements.
Nucleic Acids Research
38
(6)
, pp. 1841-1852.
10.1093/nar/gkp1183
|
|
Cogan, Nicola, Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Phillips, Ryan, Crompton, Lucy A., Caldwell, Maeve A., Rubio, Miguel A., Newson, Roger, Lyng, Fiona and Case, C. P.
2010.
DNA damaging bystander signalling from stem cells, cancer cells and fibroblasts after Cr(VI) exposure and its dependence on telomerase.
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
683
(1-2)
, pp. 1-8.
10.1016/j.mrfmmm.2009.09.012
|
|
Britt-Compton, Bethan, Wyllie, Fiona Sandra, Rowson, Janet Maud, Capper, Rebecca, Jones, Rhiannon E. and Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467
2009.
Telomere dynamics during replicative senescence are not directly modulated by conditions of oxidative stress in IMR90 fibroblast cells.
Biogerontology
10
(6)
, pp. 683-693.
10.1007/s10522-009-9216-4
|
|
Enoch, Stuart, Wall, Ivan Bernard, Peake, Matthew Arnold, Davies, Lindsay Catrina ORCID: https://orcid.org/0000-0002-4876-6270, Farrier, Jerry N., Giles, Peter James ORCID: https://orcid.org/0000-0003-3143-6854, Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Kipling, David Glyn, Price, Patricia Elaine, Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996
2009.
Increased oral fibroblast lifespan is telomerase-independent.
Journal of Dental Research
88
(10)
, pp. 916-921.
10.1177/0022034509342979
|
|
Roberts, Gareth W., Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Gallagher, Kathleen M. E., Robinson, Rhiannon Elizabeth, Pepper, Christopher John, Williams, John David and Topley, Nicholas
2009.
Functional effector memory T cells enrich the peritoneal cavity of patients treated with peritoneal dialysis.
Journal of the American Society of Nephrology
20
(9)
, pp. 1895-1900.
10.1681/ASN.2008101127
|
|
Allen, Nicholas Denby ORCID: https://orcid.org/0000-0003-4009-186X and Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467
2009.
Telomere length maintenance in stem cell populations.
Biochimica et Biophysica Acta-Molecular Basis of Disease
1792
(4)
, pp. 324-328.
10.1016/j.bbadis.2009.02.004
|
|
Britt-Compton, Bethan, Capper, Rebecca, Rowson, Jan and Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467
2009.
Short telomeres are preferentially elongated by telomerase in human cells.
FEBS Letters
583
(18)
, pp. 3076-3080.
10.1016/j.febslet.2009.08.029
|
|
Williams, Rebecca ORCID: https://orcid.org/0000-0003-2168-7369, Richardson, Kirsty, Singhrao, S. K., Jones, R. E., Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Nelson, Larissa, Lewis, H., Roberts, S., Dudhia, J., Khan, I. M. and Archer, Charles W.
2009.
A sub-population of human articular cartilage cells display stem cell/progenitor characteristics.
European Cells and Materials
18
(Supp 1)
, p. 65.
|
|
Wall, Ivan Bernard, Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735, Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Kipling, David Glyn, Giles, Peter James ORCID: https://orcid.org/0000-0003-3143-6854, Laffafian, Iraj, Price, Patricia Elaine, Thomas, David William ORCID: https://orcid.org/0000-0001-7319-5820 and Stephens, Philip ORCID: https://orcid.org/0000-0002-0840-4996
2008.
Fibroblast dysfunction is a key factor in the non-healing of chronic venous leg ulcers.
Journal of Investigative Dermatology
128
(10)
, pp. 2526-2540.
10.1038/jid.2008.114
|
|
Lin, Thet Thet, Hewamana, Saman, Ward, Rachel Mary, Taylor, Hannah, Payne, Tammy, Pratt, Guy, Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Fegan, Christopher D. ORCID: https://orcid.org/0000-0001-9685-0621 and Pepper, Christopher John
2008.
Highly purified CD38+ sub-populations show no evidence of preferential clonal evolution despite having increased proliferative activity when compared with CD38+ sub-populations derived from the same chronic lymphocytic leukaemia patient.
British Journal of Haematology
142
(4)
, pp. 595-605.
10.1111/j.1365-2141.2008.07236.x
|
|
Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467
2008.
Telomere dynamics in human cells.
Biochimie
90
(1)
, pp. 116-121.
10.1016/j.biochi.2007.08.003
|
|
Capper, Rebecca, Britt-Compton, Bethan, Tankimanova, Maira, Rowson, Janet Maud, Letsolo, Boitelo, Man, Stephen Tzekwung ORCID: https://orcid.org/0000-0001-9103-1686, Haughton, Michele Fleur and Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467
2007.
The nature of telomere fusion and a definition of the critical telomere length in human cells.
Genes and Development
21
(19)
, pp. 2495-2508.
10.1101/gad.439107
|
|
|
Papageorgiou, Iraklis, Yin, Zhirong, Ladon, Dariusz, Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Lewis, Andrew C., Sood, Aman, Newson, Roger, Learmonth, Ian D. and Case, Charles Patrick
2007.
Genotoxic effects of particles of surgical cobalt chrome alloy on human cells of different age in vitro.
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
619
(1-2)
, pp. 45-58.
10.1016/j.mrfmmm.2007.01.008
|
|
Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467
2007.
Telomeres II.
Experimental Gerontology
43
(1)
, pp. 15-19.
10.1016/j.exger.2007.10.002
|
|
Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467
2007.
Telomeres.
Marshall, V., Cole, T., Soloman, D., Masoro, E., Schaie, K., Gutman, G. and Birren, J., eds.
Encyclopaedia of Gerontology (2nd ed.),
Amsterdam:
Elsevier,
pp. 593-601.
(10.1016/B0-12-370870-2/00185-2)
|
|
Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467
2006.
Telomeres.
Experimental Gerontology
41
(12)
, pp. 1223-1227.
10.1016/j.exger.2006.09.009
|
|
Britt-Compton, Bethan, Rowson, Janet Maud, Locke, Matthew, Mackenzie, Ian, Kipling, David Glyn and Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467
2006.
Structural stability and chromosome-specific telomere length is governed by cis-acting determinants in humans.
Human Molecular Genetics
15
(5)
, pp. 725-733.
10.1093/hmg/ddi486
|
|
Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Britt-Compton, Bethan, Rowson, Janet Maud, Amso, Nazar Najib ORCID: https://orcid.org/0000-0002-8646-6623, Gregory, Linda and Kipling, David Glyn
2006.
Telomere instability in the male germline.
Human molecular genetics
15
(1)
, pp. 45-51.
10.1093/hmg/ddi424
|
|
|
Britt-Compton, Bethan and Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467
2006.
Intra-allelic mutation at human telomeres.
Biochemical Society Transactions
34
(4)
, pp. 581-582.
10.1042/BST0340581
|
|
Glaviano, A., Nayak, V., Cabuy, E., Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Yin, Z., Newson, R., Ladon, D., Rubio, M. A., Slijepcevic, P., Lyng, F., Mothersill, C. and Case, C. P.
2006.
Effects of hTERT on metal ion-induced genomic instability.
Oncogene
25
(24)
, pp. 3424-3435.
10.1038/sj.onc.1209399
|
|
Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467 and Farr, Christine J.
2006.
The organization and function of chromosomes [Meeting Report].
EMBO Reports
7
(4)
, pp. 372-376.
10.1038/sj.embor.7400661
|
|
Davis, Terence ORCID: https://orcid.org/0000-0003-2780-0262, Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Haughton, Michele Fleur, Jones, Christopher John and Kipling, David Glyn
2005.
Prevention of accelerated cell aging in Werner syndrome using a p38 mitogen-activated protein kinase inhibitor.
The Journals of Gerontology. Series A: Biological Sciences and Medical Sciences
60
(11)
, pp. 1386-93.
|
|
Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467
2005.
New developments in telomere length analysis.
Experimental Gerontology
40
(5)
, pp. 363-368.
10.1016/j.exger.2005.02.008
|
|
Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Davis, Terence ORCID: https://orcid.org/0000-0003-2780-0262, Rowson, Janet Maud, Jones, Christopher John and Kipling, David Glyn
2004.
Normal telomere erosion rates at the single cell level in Werner syndrome fibroblast cells.
Human Molecular Genetics
13
(14)
, pp. 1515-1524.
10.1093/hmg/ddh159
|
|
|
Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467 and Kipling, David Glyn
2004.
The extent and significance of telomere loss with age.
Annals of the New York Academy of Sciences
1019
(1)
, pp. 265-268.
10.1196/annals.1297.044
|
|
Pickett, Hilda Amelia, Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Hoff-Olsen, Per, Meling, Gunn Iren, Rognum, Torleiv Ole, Shaw, Jacqui, West, Kevin Paul and Royle, Nicola Jane
2004.
Telomere instability detected in sporadic colon cancers, some showing mutations in a mismatch repair gene.
Oncogene
23
(19)
, pp. 3434-3443.
10.1038/sj.onc.1207477
|
|
Cheung, Iris, Schertzer, Mike, Baross, Agnes, Rose, Ann M., Lansdorp, Peter M. and Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467
2004.
Strain-specific telomere length revealed by single telomere length analysis in Caenorhabditis elegans.
Nucleic Acids Research
32
(11)
, pp. 3383-3391.
10.1093/nar/gkh661
|
|
Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Rowson, Janet Maud, Wynford-Thomas, David and Kipling, David Glyn
2003.
Extensive allelic variation and ultrashort telomeres in senescent human cells.
Nature Genetics
33
(2)
, pp. 203-207.
10.1038/ng1084
|
|
Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467, Coleman, Joanna, Rosser, Zoe and Royle, Nicola
2000.
High levels of sequence polymorphism and linkage disequilibrium at the telomere of 12q: implications for telomere biology and human evolution.
American Journal of Human Genetics
66
(1)
, pp. 235-250.
10.1086/302721
|
|
Coleman, J., Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467 and Royle, N. J.
1999.
The plasticity of human telomeres demonstrated by a hypervariable telomere repeat array that is located on some copies of 16p and 16q.
Human Molecular Genetics
8
(9)
, pp. 1637-1646.
10.1093/hmg/8.9.1637
|
|
Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467 and Royle, N. J.
1997.
Sequences from higher primates orthologous to the human Xp/Yp telomere junction region reveal gross rearrangements and high levels of divergence.
Human Molecular Genetics
6
(13)
, pp. 2291-2299.
10.1093/hmg/6.13.2291
|
|
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