Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Browse by Schools (by year)

[up] Up a level
Group by: Creators | Item Type | No Grouping
Jump to: Article | Book Section | Thesis
Number of items: 32.

Article

Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X and Bonnet, Dominique 2014. Forgotten gems. Cell Cycle 13 (4) , pp. 503-504. 10.4161/cc.27788

Carotenuto, M., De Antonellis, P., Liguori, L., Benvenuto, G., Magliulo, D., Alonzi, A., Turino, C., Attanasio, C., Damiani, V., Bello, A. M., Vitiello, F., Pasquinelli, R., Terracciano, L., Federico, A., Fusco, A., Freeman, Jamie, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963, Decraene, C., Chiappetta, G., Piantedosi, F., Calabrese, C. and Zollo, M. 2014. H-Prune through GSK-3β interaction sustains canonical WNT/β-catenin signaling enhancing cancer progression in NSCLC. Oncotarget 5 (14) , pp. 5736-5749. 10.18632/oncotarget.2169
file

Cowley, Michael, Garfield, Alastair S., Madon-Simon, Marta, Charalambous, Marika, Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Kendrick, Howard, Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712, Parry, Aled J., Carney, Sara, Oakey, Rebecca J., Heisler, Lora K., Moorwood, Kim, Wolf, Jason B. and Ward, Andrew 2014. Developmental programming mediated by complementary roles of imprinted Grb10 in mother and pup. PLoS Biology 12 (2) , e1001799. 10.1371/journal.pbio.1001799
file

Davies, Emma Jane, Marsh Durban, Victoria ORCID: https://orcid.org/0000-0003-1645-1618, Meniel, Valerie, Williams, Geraint Trfor ORCID: https://orcid.org/0000-0003-3768-9940 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2014. PTEN loss and KRAS activation leads to the formation of serrated adenomas and metastatic carcinoma in the mouse intestine. The Journal of Pathology 233 (1) , pp. 27-38. 10.1002/path.4312

de Groot, Reinoud E. A., Ganji, Ranjani S., Bernatik, Ondrej, Lloyd-Lewis, Bethan, Seipel, Katja, Šedova, Katerina, Zdrahal, Zbynek, Dhople, Vishnu M., Dale, Trevor C. ORCID: https://orcid.org/0000-0002-4880-9963, Korswagen, Hendrik C. and Bryja, Vitezslav 2014. Huwe1-mediated ubiquitylation of dishevelled defines a negative feedback loop in the Wnt signaling pathway. Science Signaling 7 (317) , ra26. 10.1126/scisignal.2004985

DiTommaso, Tia, Cottle, Denny L., Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843, Schlüter, Holger, Kaur, Pritinder, Humbert, Patrick O. and Smyth, Ian M. 2014. Keratin 76 is required for tight junction function and maintenance of the skin barrier. PLoS Genetics 10 (10) , e1004706. 10.1371/journal.pgen.1004706
file

Elsum, I. A., Yates, L. L., Pearson, H. B. ORCID: https://orcid.org/0000-0002-3284-0843, Phesse, T. J. ORCID: https://orcid.org/0000-0001-9568-4916, Long, F., O'Donoghue, R., Ernst, M., Cullinane, C. and Humbert, P. O. 2014. Scrib heterozygosity predisposes to lung cancer and cooperates with KRas hyperactivation to accelerate lung cancer progression in vivo. Oncogene 33 (48) , pp. 5523-5533. 10.1038/onc.2013.498

Fizazi, Karim, Massard, Christophe, Bono, Petri, Jones, Robert ORCID: https://orcid.org/0000-0003-3576-9496, Kataja, Vesa, James, Nicholas, Garcia, Jorge A., Protheroe, Andrew, Tammela, Teuvo L., Elliott, Tony, Mattila, Leena, Aspegren, John, Vuorela, Annamari, Langmuir, Peter and Mustonen, Mika 2014. Activity and safety of ODM-201 in patients with progressive metastatic castration-resistant prostate cancer (ARADES): an open-label phase 1 dose-escalation and randomised phase 2 dose expansion trial. Lancet Oncology 15 (9) , pp. 975-985. 10.1016/S1470-2045(14)70240-2
file

Godde, Nathan J., Sheridan, Julie M., Smith, Lorey K., Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843, Britt, Kara L., Galea, Ryan C., Yates, Laura L., Visvader, Jane E. and Humbert, Patrick O. 2014. Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland. PLoS Genetics 10 (5) , e1004323. 10.1371/journal.pgen.1004323
file

Gödde, Nathan J, Pearson, Helen B ORCID: https://orcid.org/0000-0002-3284-0843, Smith, Lorey K and Humbert, Patrick O 2014. Dissecting the role of polarity regulators in cancer through the use of mouse models. Experimental Cell Research 328 (2) , pp. 249-257. 10.1016/j.yexcr.2014.08.036

Greenow, K. R., Clarke, A. R. ORCID: https://orcid.org/0000-0002-4281-426X, Williams, G. T. ORCID: https://orcid.org/0000-0003-3768-9940 and Jones, R. ORCID: https://orcid.org/0000-0003-3576-9496 2014. Wnt-driven intestinal tumourigenesis is suppressed by Chk1 deficiency but enhanced by conditional haploinsufficiency. Oncogene 33 , pp. 4089-4096. 10.1038/onc.2013.371

Griessinger, E., Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Pizzitola, I., Rouault-Pierre, K., Vargaftig, J., Taussig, D., Gribben, J., Lassailly, F. and Bonnet, Dominique 2014. A niche-like culture system allowing the maintenance of primary human acute myeloid leukemia-initiating cells: A new tool to decipher their chemoresistance and self-renewal mechanisms. Stem Cells Translational Medicine 3 (4) , pp. 520-529. 10.5966/sctm.2013-0166
file

Hare, Lauren M., Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Waring, Paul M., Montgomery, Karen G., Kinross, Kathryn M., Mills, Kevin, Roh, Vincent, Heath, Joan K., Ramsay, Robert G., Ernst, Matthias and Phillips, Wayne A. 2014. Physiological expression of the PI3K-activating mutationPik3caH1047Rcombines withApcloss to promote development of invasive intestinal adenocarcinomas in mice. Biochemical Journal 458 (2) , pp. 251-258. 10.1042/BJ20131412

Hickman, John A., Graeser, Ralph, de Hoogt, Ronald, Vidic, Suzana, Brito, Catarina, Gutekunst, Matthias, van der Kuip, Heiko, consortium, IMI PREDECT and Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146 2014. Three-dimensional models of cancer for pharmacology and cancer cell biology: Capturing tumor complexity in vitro/ex vivo. Biotechnology Journal 9 (9) , pp. 1115-1128. 10.1002/biot.201300492

Holik, Aliaksei Z., Young, Madeleine, Krzystyniak, Joanna, Williams, Geraint T. ORCID: https://orcid.org/0000-0003-3768-9940, Metzger, Daniel, Shorning, Boris Y. and Clarke, Alan R. ORCID: https://orcid.org/0000-0002-4281-426X 2014. Brg1 loss attenuates aberrant Wnt-signalling and prevents Wnt-dependent tumourigenesis in the murine small intestine. PLoS Genetics 10 (7) , e1004453. 10.1371/journal.pgen.1004453
file

Infantino, S., Jones, S. A., Walker, J. A., Maxwell, M. J., Light, A., O'Donnell, K., Tsantikos, E., Peperzak, V., Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Ernst, M., Mackay, F., Hibbs, M. L., Fairfax, K. A. and Tarlinton, D. M. 2014. The tyrosine kinase Lyn limits the cytokine responsiveness of plasma cells to restrict their accumulation in mice. Science Signaling 7 (338) , ra77. 10.1126/scisignal.2005105

Khurana, Rimpi, Verma, Vinod, Rawoof, Abdul, Tiwari, Shrish, Nair, Rekha A., Mahidhara, Ganesh, Idris, Mohammed M., Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X and Kumar, Lekha 2014. OncomiRdbB: a comprehensive database of microRNAs and their targets in breast cancer. BMC Bioinformatics 15 (1) , p. 15. 10.1186/1471-2105-15-15
file

Koh, D. -I., Han, D., Ryu, H., Choi, W.-I., Jeon, B. -N., Kim, M. -K., Kim, Y., Kim, J. Y., Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X, Reynolds, A. B. and Hur, M. -W. 2014. KAISO, a critical regulator of p53-mediated transcription of CDKN1A and apoptotic genes. Proceedings of the National Academy of Sciences of the United States of America 111 (42) , pp. 15078-15083. 10.1073/pnas.1318780111

Marsh Durban, Victoria ORCID: https://orcid.org/0000-0003-1645-1618, Jansen, Marnix, Davies, Emma Jane, Morsink, Folkert H., Offerhaus, G. Johan A. and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2014. Epithelial-specific loss of PTEN results in colorectal juvenile polyp formation and invasive cancer. American Journal of Pathology 184 (1) , pp. 86-91. 10.1016/j.ajpath.2013.10.003

Melchor, Lorenzo, Molyneux, Gemma, Mackay, Alan, Magnay, Fiona-Ann, Atienza, María, Kendrick, Howard, Nava-Rodrigues, Daniel, López-García, María Ángeles, Milanezi, Fernanda, Greenow, Kirsty, Robertson, David, Palacios, José, Reis-Filho, Jorge S. and Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 2014. Identification of cellular and genetic drivers of breast cancer heterogeneity in genetically engineered mouse tumour models. Journal of Pathology 233 (2) , pp. 124-137. 10.1002/path.4345
filefilefilefilefilefilefile

Phesse, T. J. ORCID: https://orcid.org/0000-0001-9568-4916, Myant, K. B., Cole, A. M., Ridgway, R. A., Pearson, H. ORCID: https://orcid.org/0000-0002-3284-0843, Muncan, V., van den Brink, G. R., Vousden, K. H., Sears, R., Vassilev, L . T ., Clarke, A. R. ORCID: https://orcid.org/0000-0002-4281-426X and Sansom, O. J. 2014. Endogenous c-Myc is essential for p53-induced apoptosis in response to DNA damage in vivo. Cell Death and Differentiation 21 (6) , pp. 956-966. 10.1038/cdd.2014.15
file

Phesse, Toby J. ORCID: https://orcid.org/0000-0001-9568-4916, Buchert, Michael, Stuart, Emma, Flanagan, Dustin J., Faux, Maree, Afshar-Sterle, Shoukat, Walker, Francesca, Zhang, Hui-Hua, Nowell, Cameron J., Jorissen, Robert, Tan, Chin Wee, Hirokawa, Yumiko, Eissmann, Moritz F., Poh, Ashleigh R., Malaterre, Jordane, Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843, Kirsch, David G., Provero, Paolo, Poli, Valeria, Ramsay, Robert G., Sieber, Oliver, Burgess, Antony W., Huszar, Dennis, Vincan, Elizabeth and Ernst, Matthias 2014. Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt–β-catenin–mediated intestinal tumor growth and regeneration. Science Signaling 7 (345) , ra92. 10.1126/scisignal.2005411

Pizzitola, I., Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, Rouault-Pierre, K., Lassailly, F., Tettamanti, S., Spinelli, O., Biondi, A., Biagi, E. and Bonnet, D. 2014. Chimeric antigen receptors against CD33/CD123 antigens efficiently target primary acute myeloid leukemia cells in vivo. Leukemia 28 , pp. 1596-1605. 10.1038/leu.2014.62

Rickard, James A., O'Donnell, Joanne A., Evans, Joseph M., Lalaoui, Najoua, Poh, Ashleigh R., Rogers, TeWhiti, Vince, James E., Lawlor, Kate E., Ninnis, Robert L., Anderton, Holly, Hall, Cathrine, Spall, Sukhdeep K., Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Abud, Helen E., Cengia, Louise H., Corbin, Jason, Mifsud, Sandra, Di Rago, Ladina, Metcalf, Donald, Ernst, Matthias, Dewson, Grant, Roberts, Andrew W., Alexander, Warren S., Murphy, James M., Ekert, Paul G., Masters, Seth L., Vaux, David L., Croker, Ben A., Gerlic, Motti and Silke, John 2014. RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis. Cell 157 (5) , pp. 1175-1188. 10.1016/j.cell.2014.04.019

Sarkisian, Matthew R., Siebzehnrubl, Dorit, Hoang-Minh, Lan, Deleyrolle, Loic, Silver, Daniel J., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Guadiana, Sarah M., Srivinasan, Gayathri, Semple-Rowland, Susan, Harrison, Jeffrey K., Steindler, Dennis A. and Reynolds, Brent A. 2014. Detection of primary cilia in human glioblastoma. Journal of Neuro-Oncology 117 (1) , pp. 15-24. 10.1007/s11060-013-1340-y

Stuart, E., Buchert, M., Putoczki, T., Thiem, S., Farid, R., Elzer, J., Huszar, D., Waring, P. M., Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916 and Ernst, M. 2014. Therapeutic inhibition of jak activity inhibits progression of gastrointestinal tumors in mice. Molecular Cancer Therapeutics 13 (2) , p. 468. 10.1158/1535-7163.MCT-13-0583-T

Suhalim, Jeffrey L., Parfitt, Geraint J ORCID: https://orcid.org/0000-0002-8704-7906, Xie, Yilu, De Paiva, Cintia S., Pflugfelder, Stephen C., Shah, Tejas N., Potma, Eric O., Brown, Donald J. and Jester, James V. 2014. Effect of desiccating stress on mouse meibomian gland function. Ocular Surface 12 (1) , pp. 59-68. 10.1016/j.jtos.2013.08.002

Tanguay, J. S., Wheeler, P., Button, M., Stevens, R., Shaw, Paul ORCID: https://orcid.org/0000-0002-7467-0619, Brewster, A., Hanna, L. and Lester, J. F. 2014. Limited stage small cell lung cancer (LS SCLC) South East Wales experience. Lung Cancer 88 (Supp 1) , S66. 10.1016/S0169-5002(14)70180-1

Tornillo, Giusy and Cabodi, Sara 2014. 3D mammary colony-forming cell assay. Bio-Protocol 4 (7)

Vedam-Mai, Vinata, Gardner, Bronwen, Okun, Michael S., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Kam, Monica, Aponso, Palingu, Steindler, Dennis A., Yachnis, Anthony T., Neal, Dan, Oliver, Brittany U., Rath, Sean J., Faull, Richard L. M., Reynolds, Brent A. and Curtis, Maurice A. 2014. Increased precursor cell proliferation after deep brain stimulation for Parkinson's disease: a human study. PLoS ONE 9 (3) , e88770. 10.1371/journal.pone.0088770
file

Book Section

Rudge, Felicity and Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963 2014. Therapeutic targeting of the Wnt signaling network. Hoppler, Stefan P. and Moon, Randall T., eds. Wnt Signaling in Development and Disease: Molecular Mechanisms and Biological Functions, John Wiley & Sons, pp. 421-443.

Thesis

Krzystyniak, Joanna 2014. Epigenetic modulation of intestinal homeostasis and tumorigenesis by Brm SWI/SNF chromatin remodelling factor. PhD Thesis, Cardiff University.
Item availability restricted.
filefile

This list was generated on Sat Apr 19 10:09:25 2025 BST.


Maintained by Cardiff University Information Services