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Number of items: 32.

Best, Hannah, Williamson, Lainey J., Cutts, Adam B., Galchenkova, Marina, Yefanov, Oleksandr, Bryce-Sharron, Nicole, Heath, Emily A., de Wijn, Raphael, Schubert, Robin, Munke, Anna, Henkel, Alessandra, Klopprogge, Bjarne, Scheer, T. Emilie S., Kremling, Viviane, Awel, Salah, Pena, Gisel, Knoska, Juraj, Keloth, Anusha, Maracke, Julia, Letrun, Romain, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Berry, Colin ORCID: https://orcid.org/0000-0002-9943-548X 2026. The long and short of it: Distinct natural crystal packing strategies of Cry toxins from Bacillus thuringiensis. Structure 10.1016/j.str.2026.01.014
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Kirkham, Emily, Gardiner, Sian, Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611, Best, Hannah and Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 2025. Lysosomal pH measurements via dual-imaging microscopy. Hughes, Stephanie M. and Basak, Indranil, eds. Lysosomes: Methods and Protocols, Vol. 2976. Methods in Molecular Biology, New York, New York, USA: pp. 11-24. (10.1007/978-1-0716-4844-5_2)

Riseley, Ross, Carneiro, Aitor, Mu, Zhilin, Alkahtani, Rawiyah, Kariuki, Benson ORCID: https://orcid.org/0000-0002-8658-3897, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 and Jones, D. Heulyn 2025. Unusual reactivity of 2-amino-1H-indole-3-carboxylate esters. ARKIVOC 2025 (5) , 202512417. 10.24820/ark.5550190.p012.417
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Reeks, Judith, Mahajan, Pravin, Clark, Mellissa, Cowan, Suzanna R., Di Daniel, Elena, Earl, Christopher P., Fisher, Samantha, Holvey, Rhian S., Jackson, Scott M., Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611, Morgillo, Carmine M., Mortenson, Paul N., O'Reilly, Marc, Richardson, Caroline J., Schöpf, Patrick, Tams, Daniel M., Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Ward, Simon E. ORCID: https://orcid.org/0000-0002-8745-8377, Whibley, Stuart, Williams, Pamela A. and Johnson, Christopher N. 2025. High throughput cryo-EM provides structural understanding for modulators of the lysosomal ion channel TRPML1. Structure 33 (8) , pp. 1374-1385. 10.1016/j.str.2025.05.014
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Best, Hannah L., Cook, Sophie R., Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 and Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 2025. Niemann-Pick C-like endo-lysosomal dysfunction in DHDDS patient cells, a congenital disorder of glycosylation, can be treated with miglustat. International Journal of Molecular Sciences 26 (4) , 1471. 10.3390/ijms26041471
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Cubitt, Jonathan, Davies, Mari, Riseley, Ross, Evans, Gabrielle, Gardiner, Sian E., Kariuki, Benson M. ORCID: https://orcid.org/0000-0002-8658-3897, Ward, Simon E. ORCID: https://orcid.org/0000-0002-8745-8377, Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 and Jones, D. Heulyn 2024. Beware of N-Benzoyloxybenzamides. Molecules 29 (21) , 5143. 10.3390/molecules29215143
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Best, Hannah L., Williamson, Lainey J., Heath, Emily A., Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 and Berry, Colin ORCID: https://orcid.org/0000-0002-9943-548X 2023. The role of glycoconjugates as receptors for insecticidal proteins. FEMS Microbiology Reviews 47 (4) 10.1093/femsre/fuad026
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Somogyi, Aleksandra, Kirkham, Emily D., Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611, Winston, Jincy, Allen, Nicholas D. ORCID: https://orcid.org/0000-0003-4009-186X, Mackrill, John J., Anderson, Karen E., Hawkins, Phillip T., Gardiner, Sian E., Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Sims, Rebecca ORCID: https://orcid.org/0000-0002-3885-1199, Boland, Barry and O'Neill, Cora 2023. The synthetic TRPML1 agonist ML-SA1 rescues Alzheimer-related alterations of the endosomal-autophagic-lysosomal system. Journal of Cell Science 136 (6) , jcs259875. 10.1242/jcs.259875
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Fenn, Gareth D., Alenazy, Deemah M., Pope, Simon ORCID: https://orcid.org/0000-0001-9110-9711, Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 and Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 2023. Development of a novel anthraquinone-derived fluorescent lysosomal probe. Molecular Genetics and Metabolism 138 (2) , 107097. 10.1016/j.ymgme.2022.107097
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Best, Hannah, Honeybun, Llinos, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 and Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 2023. The Batten disease associated protein CLN3 is required for the efflux of lysosomal K. Presented at: 19th Annual WORLDSymposium™ 2023, Orlando, Florida, 21-26 February 2023. Molecular Genetics and Metabolism. , vol.138 (2) Elsevier, p. 47. 10.1016/j.ymgme.2022.107030

Honeybun, Llinos, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 and Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 2023. Unbiased phenotypic drug screen for CLN3 disease. Presented at: 19th Annual WORLDSymposium™ 2023, Orlando, Florida, 21-26 February 2023. Molecular Genetics and Metabolism. , vol.138 (2) Elsevier, p. 167. 10.1016/j.ymgme.2022.107150

Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Zhu, Jingwen, Honeybun, Llinos, Gardiner, Sian, Hanley, Marcus, Best, Hannah and Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 2023. Measuring ion flux via lysosomal channels: Primary and secondary assays for drug discovery across the lysosomal disorders. Presented at: 19th Annual WORLDSymposium™ 2023, Orlando, Florida, 21-26 February 2023. Molecular Genetics and Metabolism. , vol.138 (2) Elsevier, pp. 133-134. 10.1016/j.ymgme.2022.107353

Fenn, Gareth D., Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 and Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 2023. Investigation of cannabidiol as a potential therapeutic in Niemann-Pick disease. Presented at: 19th Annual WORLDSymposium™ 2023, Orlando, Florida, 21-26 February 2023. Molecular Genetics and Metabolism. , vol.138 (2) Elsevier, p. 42. 10.1016/j.ymgme.2022.107098

Cook, Sophie R., Kirkham, Emily D., Best, Hannah, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Serpi, Michaela ORCID: https://orcid.org/0000-0002-6162-7910, Pertusati, Fabrizio ORCID: https://orcid.org/0000-0003-4532-9101 and Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 2023. Investigating lysosomal and cellular phenotypes of the lysosomal disorder cystinosis. Presented at: 19th Annual WORLDSymposium™ 2023, Orlando, Florida, 21-26 February 2023. Molecular Genetics and Metabolism. , vol.138 (2) Elsevier, p. 28. 10.1016/j.ymgme.2022.107061

Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611, Best, Hannah L., Alshehri, Abdullah S., Honeybun, Llinos and Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 2023. Glycosphingolipid reduction with miglustat as a therapeutic strategy for CLN3 and other neuronal ceroid lipofuscinoses. Presented at: 19th Annual WORLDSymposium™ 2023, Orlando, Florida, 21-26 February 2023. Molecular Genetics and Metabolism. , vol.138 (2) Elsevier, p. 84. 10.1016/j.ymgme.2022.107212

Best, Hannah L., Badell-Grau, Rafael A., Shipley, Katie, Alshehri, Abdullah S., Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 and Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 2023. Disease phenotypes present in CLN7 patient fibroblasts are improved following treatment to reduce glycosphingolipid synthesis. Presented at: 19th Annual WORLDSymposium™ 2023, Orlando, Florida, 21-26 February 2023. Molecular Genetics and Metabolism. , vol.138 (2) Elsevier, p. 17. 10.1016/j.ymgme.2022.107029

Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Francis, Laura, Fenn, Gareth, Best, Hannah and Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 2023. Filipin composition and imaging modality dramatically affect cellular cholesterol visualisation with implications for assessing cholesterol levels and localisation across the lysosomal disorders. Presented at: 19th Annual WORLDSymposium™ 2023, Orlando, Florida, 21-26 February 2023. Molecular Genetics and Metabolism. , vol.138 (2) Elsevier, p. 133. 10.1016/j.ymgme.2022.107352

Davies, Mari, Riseley, Ross, Jones, Dyfyr H. and Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 2023. Acid ceramidase inhibition as a mechanism to treat lysosomal disorders. Molecular Genetics and Metabolism 138 (2) , 107069. 10.1016/j.ymgme.2022.107069

Best, Hannah L., Williamson, Lainey J., Lipka-Lloyd, Magdalena, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Berry, Colin ORCID: https://orcid.org/0000-0002-9943-548X 2022. The crystal structure of Bacillus thuringiensis Tpp80Aa1 and its interaction with galactose-containing glycolipids. Toxins 14 (12) , 863. 10.3390/toxins14120863
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Cook, Sophie R, Bladen, Cerys, Smith, Johanna, Maguire, Emily, Copner, Jordan, Fenn, Gareth D, Wager, Kim ORCID: https://orcid.org/0000-0001-8107-9600, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 and Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 2020. Visualisation of cholesterol and ganglioside GM1 in zebrafish models of Niemann-Pick type C disease and Smith-Lemli-Opitz syndrome using light sheet microscopy. Histochemistry and Cell Biology 154 , pp. 565-578. 10.1007/s00418-020-01925-2
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Badell Grau, Rafael A., Cuff, Jordan Patrick, Kelly, Brendan P., Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 and Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 2020. Investigating the prevalence of reactive online searching in the COVID-19 pandemic. Journal of Medical Internet Research 22 (10) , e19791. 10.2196/19791
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Fenn, Gareth, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Atack, John R. ORCID: https://orcid.org/0000-0002-3410-791X and Bax, Benjamin D. ORCID: https://orcid.org/0000-0003-1940-3785 2020. Crystallization and structure of ebselen bound to cysteine 141 of human inositol monophosphatase (IMPase). Acta Crystallographica Section F: Structural Biology Communications F76 (10) , pp. 469-476. 10.1107/S2053230X20011310
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Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 and Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 2020. Biosynthesis and signalling functions of central and peripheral nervous system neurosteroids in health and disease. Essays in Biochemistry 64 (3) , pp. 591-606. 10.1042/EBC20200043
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Cook, Sophie R., Badell-Grau, Rafael A., Kirkham, Emily D., Jones, Kimberley M., Kelly, Brendan M., Winston, Jincy, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Allen, Nicholas D. ORCID: https://orcid.org/0000-0003-4009-186X and Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 2020. Detrimental effect of zwitterionic buffers on lysosomal homeostasis in cell lines and iPSC-derived neurons. AMRC Open Research 2 , 21. 10.12688/amrcopenres.12903.1
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Morimoto, Marie, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Ammous, Zineb, Song, Xiaofei, Strauss, Kevin A., Pehlivan, Davut, Gonzaga-Jauregui, Claudia, Puffenberger, Erik G., Holst, Charles R., Karaca, Ender, Brigatti, Karlla W., Maguire, Emily, Coban-Akdemir, Zeynep H., Amagata, Akiko, Lau, C. Christopher, Chepa-Lotrea, Xenia, Macnamara, Ellen, Tos, Tulay, Isikay, Sedat, Nehrebecky, Michele, Overton, John D., Klein, Matthew, Markello, Thomas C., Posey, Jennifer E., Adams, David R., Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611, Lupski, James R., Gahl, William A. and Malicdan, May Christine V. 2018. Bi-allelic CCDC47 variants cause a disorder characterized by woolly hair, liver dysfunction, dysmorphic features, and global developmental delay. American Journal of Human Genetics 103 (5) , pp. 794-807. 10.1016/j.ajhg.2018.09.014

Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064 and Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611 2015. Regulation of TRPML1 function. Biochemical Society Transactions 43 (3) , pp. 442-446. 10.1042/BST20140311

Kaisaki, Pamela J., Otto, Georg W., McGouran, Joanna F., Toubal, Amine, Argoud, Karène, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Finlay, Clare, Caldérari, Sophie, Bihoreau, Marie-Thérèse, Kessler, Benedikt M., Gauguier, Dominique and Mott, Richard 2014. Genetic control of differential acetylation in diabetic rats. PLoS ONE 9 (4) , e94555. 10.1371/journal.pone.0094555
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Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Hue, Christophe, Fearnside, Jane, Rothwell, Alice R., Lockstone, Helen E., Caldérari, Sophie, Wilder, Steven P., Cazier, Jean-Baptiste, Scott, James and Gauguier, Dominique 2013. Nutrigenomics of high fat diet induced obesity in mice suggests relationships between susceptibility to fatty liver disease and the proteasome. PLoS ONE 8 (12) , e82825. 10.1371/journal.pone.0082825

Prömel, Simone, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Dixon, John, Zahn, Dirk, Colledge, William H., Doran, Joanne, Carlton, Mark B.L., Grosse, Johannes, Schöneberg, Torsten, Russ, Andreas P. and Langenhan, Tobias 2012. Characterization and functional study of a cluster of four highly conserved orphan adhesion-GPCR in mouse. Developmental Dynamics 241 (10) , pp. 1591-1602. 10.1002/dvdy.23841

Lloyd-Evans, Emyr ORCID: https://orcid.org/0000-0002-3626-1611, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Peterneva, Ksenia and Platt, Frances M. 2010. Endolysosomal calcium regulation and disease. Biochemical Society Transactions 38 (6) , pp. 1458-1464. 10.1042/BST0381458

Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Prömel, Simone, Langenhan, Tobias, Dixon, John, Zahn, Dirk, Colledge, William H., Doran, Joanne, Carlton, Mark B. L., Davies, Ben, Aparicio, Samuel A. J. R., Grosse, Johannes and Russ, Andreas P. 2010. The orphan adhesion-GPCR GPR126 is required for embryonic development in the mouse. PLoS ONE 5 (11) , e14047. 10.1371/journal.pone.0014047
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Langenhan, Tobias, Prömel, Simone, Mestek, Lamia, Esmaeili, Behrooz, Waller-Evans, Helen ORCID: https://orcid.org/0000-0003-4133-6064, Hennig, Christian, Kohara, Yuji, Avery, Leon, Vakonakis, Ioannis, Schnabel, Ralf and Russ, Andreas P. 2009. Latrophilin signaling links anterior-posterior tissue polarity and oriented cell divisions in the C. elegans embryo. Developmental Cell 17 (4) , pp. 494-504. 10.1016/j.devcel.2009.08.008

This list was generated on Sat Mar 14 10:30:08 2026 GMT.


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