ORCA
Online Research @ Cardiff
Browse by Current Cardiff authors
![[up]](/style/images/multi_up.png)
Up a levelNumber of items: 74.
Bains, Kiranjit K.  ORCID: https://orcid.org/0000-0001-6617-5768, Ashworth, Sean, Koudouna, Elena ORCID: https://orcid.org/0000-0002-9959-4667, Young, Robert D. ORCID: https://orcid.org/0000-0002-8300-8002, Hughes, Clare E. ORCID: https://orcid.org/0000-0003-4726-5877 and Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120
2023.
Chondroitin sulphate/dermatan sulphate proteoglycans: potential regulators of corneal stem/progenitor cell phenotype in vitro.
International Journal of Molecular Sciences
24
(3)
, 2095.
10.3390/ijms24032095
|
|
|
Mutoji, Kazadi N., Sun, Mingxia, Elliott, Garrett, Moreno, Isabel Y., Hughes, Clare ORCID: https://orcid.org/0000-0003-4726-5877, Gesteira, Tarsis F. and Coulson-Thomas, Vivien J.
2021.
Extracellular matrix deposition and remodeling after corneal alkali burn in mice.
International Journal of Molecular Sciences
22
(11)
, 5708.
10.3390/ijms22115708
|
|
|
|
Allaith, S., Tew, S. R., Hughes, C. E. ORCID: https://orcid.org/0000-0003-4726-5877, Clegg, P. D., Canty-Laird, E. G. and Comerford, E. J.
2021.
Characterisation of key proteoglycans in the cranial cruciate ligaments (CCLs) from two dog breeds with different predispositions to CCL disease and rupture.
The Veterinary Journal
272
, 105657.
10.1016/j.tvjl.2021.105657
|
|
|
Ashworth, Sean, Harrington, Jodie, Hammond, Greg M., Bains, Kiranjit K. ORCID: https://orcid.org/0000-0001-6617-5768, Koudouna, Elena ORCID: https://orcid.org/0000-0002-9959-4667, Hayes, Anthony J., Ralphs, James R. ORCID: https://orcid.org/0000-0002-5367-0732, Regini, Justyn W. ORCID: https://orcid.org/0000-0001-6149-5893, Young, Robert D. ORCID: https://orcid.org/0000-0002-8300-8002, Hayashi, Ryuhei, Nishida, Kohji, Hughes, Clare E. ORCID: https://orcid.org/0000-0003-4726-5877 and Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120
2021.
Chondroitin sulfate as a potential modulator of the stem cell niche in cornea.
Frontiers in Cell and Developmental Biology
8
, 567358.
10.3389/fcell.2020.567358
|
|
|
|
Nandadasa, Sumeda, Szafron, Jason M., Pathak, Vai, Murtada, Sae-Il, Kraft, Caroline M., O'Donnell, Anna, Norvik, Christian, Hughes, Clare ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Domowicz, Miriam S., Schwartz, Nancy B., Tran-Lundmark, Karin, Veigl, Martina, Sedwick, David, Philipson, Elliot H., Humphrey, Jay D. and Apte, Suneel S.
2020.
Vascular dimorphism ensured by regulated proteoglycan dynamics favors rapid umbilical artery closure at birth.
eLife
9
, e60683.
10.7554/eLife.60683
|
|
|
|
Powell, Alison, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Hughes, Clare ORCID: https://orcid.org/0000-0003-4726-5877, Paul, Alison ORCID: https://orcid.org/0000-0002-7653-9964, James, Craig ORCID: https://orcid.org/0000-0002-0569-182X, Hopkins, Stephen, Mansour, Omar and Griffiths, Peter
2017.
Do model polymer therapeutics sufficiently diffuse through articular cartilage to be a viable therapeutic route?
Journal of Drug Targeting
25
(9-10)
, pp. 919-926.
10.1080/1061186X.2017.1378660
|
|
|
|
Hayes, Anthony Joseph, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Smith, Susan M., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Little, Christopher B. and Melrose, James
2016.
The CS sulphation motifs 4C3, 7D4, 3B3[-]; and perlecan identify stem cell populations and niches, activated progenitor cells and transitional tissue development in the fetal human elbow.
Stem Cells and Development
25
(11)
, pp. 836-847.
10.1089/scd.2016.0054
|
|
|
|
Bascoul-Colombo, Cecile, Garaiova, Iveta, Plummer, Sue F., Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hughes, Clare E. ORCID: https://orcid.org/0000-0003-4726-5877
2016.
Glucosamine hydrochloride but not chondroitin sulfate prevents cartilage degradation and inflammation induced by interleukin-1α in bovine cartilage explants.
Cartilage
7
(1)
, pp. 70-81.
10.1177/1947603515603762
|
|
|
|
Esa, Adam, Archer, C. W., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hughes, Clare E. ORCID: https://orcid.org/0000-0003-4726-5877
2015.
Investigating the role of Wnt antagonist protein Dkk-1 in the pathogenesis of osteoarthritis [Abstract].
International Journal of Experimental Pathology
96
(2)
, A29-A29.
10.1111/iep.12125
|
|
|
|
Chen, Jinghong, Luo, Mingxiu, Wang, Wei, Zhang, Zentie, Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Cao, Junling
2015.
Altered proteolytic activity and expression of mmps and aggrecanases and their inhibitors in Kashin-Beck disease.
Journal of Orthopaedic Research
33
(1)
, pp. 47-55.
10.1002/jor.22708
|
|
|
|
Luo, M., Chen, J., Li, S., Sun, H., Zhang, Z., Fu, Q., Li, J., Wang, J., Hughes, C. E. ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, B. ORCID: https://orcid.org/0000-0001-6016-0661 and Cao, J.
2014.
Changes in the metabolism of chondroitin sulfate glycosaminoglycans in articular cartilage from patients with Kashin-Beck disease.
Osteoarthritis and Cartilage
22
(7)
, pp. 986-995.
10.1016/j.joca.2014.05.012
|
|
|
|
Shu, Cindy, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Smith, Susan M., Smith, Margaret M., Hayes, Anthony Joseph, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Little, Christopher B. and Melrose, James
2013.
The ovine newborn and human foetal intervertebral disc contain perlecan and aggrecan variably substituted with native 7D4 CS sulphation motif: spatiotemporal immunolocalisation and co-distribution with Notch-1 in the human foetal disc.
Glycoconjugate Journal
30
(7)
, pp. 717-725.
10.1007/s10719-013-9475-9
|
|
|
|
Guan, Fang, Li, Siyuan, Wang, Zhi-lun, Yang, Haojie, Xue, Senghai, Wang, Wei, Song, Daiqing, Zhou, Xiaorong, Zhou, Wang, Chen, Jing-hong, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877
2013.
Histopathology of chondronecrosis development in knee articular cartilage in a rat model of Kashin-Beck disease using T-2 toxin and selenium deficiency conditions.
Rheumatology International
33
(1)
, pp. 157-166.
10.1007/s00296-011-2335-7
|
|
|
|
Li, Siyuan, Hayes, Anthony Joseph, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877
2013.
The effect of beta-xylosides on the chondrogenic differentiation of mesenchymal stem cells.
Histochemistry and Cell Biology
139
(1)
, pp. 59-74.
10.1007/s00418-012-1017-1
|
|
|
|
Bondeson, Jan, Wainwright, Shane Daniel, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877
2013.
ADAMTS4.
Rawlings, Neil D. and Salvesen, Guy, eds.
Handbook of Proteolytic Enzymes. 3rd ed.,
Vol. 1.
London:
Academic Press,
pp. 1166-1173.
(10.1016/B978-0-12-382219-2.00262-3)
|
|
|
|
Bondeson, Jan, Wainwright, Shane Daniel, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877
2013.
ADAMTS5.
Rawlings, Neil D. and Salvesen, G., eds.
Handbook of Proteolytic Enzymes. 3rd ed.,
Vol. 1.
London:
Academic Press,
pp. 1174-1180.
(10.1016/B978-0-12-382219-2.00263-5)
|
|
|
|
Melrose, James, Isaacs, Marc D., Smith, Susan M., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Little, Christopher B., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hayes, Anthony Joseph
2012.
Chondroitin sulphate and heparan sulphate sulphation motifs and their proteoglycans are involved in articular cartilage formation during human foetal knee joint development.
Histochemistry and Cell Biology
138
(3)
, pp. 461-475.
10.1007/s00418-012-0968-6
|
|
|
|
Serpi, Michaela ORCID: https://orcid.org/0000-0002-6162-7910, Bibbo, Rita, Rat, Stephanie, Roberts, Helen Christina, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Alcaraz, María José, Gibert, Anna Torrent, Verson, Carlos Raul Alaez and McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X
2012.
Novel phosphoramidate prodrugs of N-Acetyl-(d)-Glucosamine with antidegenerative activity on bovine and human cartilage explants.
Journal of Medicinal Chemistry
55
(10)
, pp. 4629-4639.
10.1021/jm300074y
|
|
|
|
Li, Siyuan, Cao, Junling, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877
2012.
Proteoglycan metabolism, cell death and Kashin-Beck Disease.
Glycoconjugate Journal
29
(5-6)
, pp. 241-248.
10.1007/s10719-012-9421-2
|
|
|
|
Liles, Melody, Palka, Barbara Paulina, Harris, Anthony, Kerr, Briedgeen, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120
2010.
Differential relative sulfation of keratan sulfate glycosaminoglycan in the chick cornea during embryonic development.
Investigative Ophthalmology and Visual Science
51
(3)
, pp. 1365-1372.
10.1167/iovs.09-4004
|
|
|
|
Bondeson, Jan, Blom, Arjen B., Wainwright, Shane Daniel, Hughes, Clare ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and van den Berg, Wim B.
2010.
The role of synovial macrophages and macrophage-produced mediators in driving inflammatory and destructive responses in osteoarthritis.
Arthritis & Rheumatism
62
(3)
, pp. 647-657.
10.1002/art.27290
|
|
|
|
Zhang, A., Cao, J. L., Yang, B., Chen, J. H., Zhang, Z. T., Li, Siyuan, Fu, Q., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661
2010.
Effects of moniliformin and selenium on human articular cartilage metabolism and their potential relationships to the pathogenesis of Kashin-Beck disease.
Journal of Zhejiang University-Science B
11
(3)
, pp. 200-208.
10.1631/jzus.B0900074
|
|
|
|
Hurst, S., Zainal, Z., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 and Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612
2010.
Dietary fatty acids and arthritis.
Prostaglandins Leukotrienes & Essential Fatty Acids
82
(4-6)
, pp. 315-318.
10.1016/j.plefa.2010.02.008
|
|
|
|
Zainal, Z., Longman, Andrea Jane, Hurst, S., Duggan, K., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 and Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612
2009.
Relative efficacies of omega-3 polyunsaturated fatty acids in reducing expression of key proteins in a model system for studying osteoarthritis.
Osteoarthritis and Cartilage
17
(7)
, pp. 896-905.
10.1016/j.joca.2008.12.009
|
|
|
|
Clarkin, C. E., Cheung, I., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Poulet, B., Edwards, J., Wheeler-Jones, C. P. D, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Pitsillides, A. A.
2009.
Phenotypic plasticity of superficial zone chondrocytes is revealed by increased glycosaminoglycan release and a unique angiogenic secretory profile from neo-cartilage grafts [Abstract].
International Journal of Experimental Pathology
90
(2)
, A103-A104.
10.1111/j.1365-2613.2009.00644.x
|
|
|
|
Roberts, Helen Christina, Serpi, M., Bibbo, R., McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Gilbert, A. T., Verson, C. R. A., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877
2009.
Chemically modified glucosamine inhibits the release of proteoglycan in a model system of articular cartilage degradation.
International Journal of Experimental Pathology
90
(1)
, A78-A79.
|
|
|
|
Roberts, Helen Christina, Serpi, M., Bibbo, R., McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Gilbert, A., Verson, C. R. A., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877
2009.
Chemically modified glucosamine inhibits the release of proteoglycan in a model system of articular cartilage degradation [Abstract].
International Journal of Experimental Pathology
90
(1)
, A78-A79.
10.1111/j.1365-2613.2008.00612.x
|
|
|
|
Rees, S. G., Waggett, A. D., Kerr, Briedgeen, Probert, J., Gealy, Elizabeth Claire, Dent, C. M., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877
2009.
Immunolocalisation and expression of keratocan in tendon.
Osteoarthritis and Cartilage
17
(2)
, pp. 276-279.
10.1016/j.joca.2008.07.007
|
|
|
|
Zainal, Z., Longman, Andrea Jane, Hurst, S., Duggan, K., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Harwood, John ORCID: https://orcid.org/0000-0003-2377-2612
2009.
Modification of Palm Oil for Anti-Inflammatory Nutraceutical Properties.
Lipids
44
(7)
, pp. 581-592.
10.1007/s11745-009-3304-8
|
|
|
|
Melrose, James, Fuller, Emily S., Roughley, Peter J., Smith, Margaret M., Kerr, Briedgeen, Hughes, Clare E ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Little, Christopher B,
2008.
Fragmentation of decorin, biglycan, lumican and keratocan is elevated in degenerate human meniscus, knee and hip articular cartilages compared with age-matched macroscopically normal and control tissues.
Arthritis Research & Therapy
10
(4)
, R79.
10.1186/ar2453
|
|
|
|
Cao, J., Li, S., Shi, Z., Yue, Y., Sun, J., Chen, J., Fu, Q., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661
2008.
Articular cartilage metabolism in patients with Kashin-Beck Disease: an endemic osteoarthropathy in China.
Osteoarthritis and Cartilage
16
(6)
, pp. 680-8.
10.1016/j.joca.2007.09.002
|
|
|
|
Hayes, Anthony Joseph, Tudor, Debbie, Nowell, Mari Ann, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877
2008.
Chondroitin sulfate sulfation motifs as putative biomarkers for isolation of articular cartilage progenitor cells.
Journal of Histochemistry & Cytochemistry
56
(2)
, pp. 125-38.
10.1369/jhc.7A7320.2007
|
|
|
|
Akhtar, S., Kerr, Briedgeen, Hayes, Anthony Joseph, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Meek, Keith Michael ORCID: https://orcid.org/0000-0002-9948-7538 and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661
2008.
Immunochemical localisation of keratan sulphate proteoglycans in cornea, sclera and limbus using a keratanase generated neoepitope monoclonal antibody.
Investigative Ophthalmology and Visual Science
49
(6)
, pp. 2424-2431.
10.1167/iovs.06-1498
|
|
|
|
Bondeson, Jan, Wainwright, Shane Daniel, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661
2008.
The regulation of ADAMTS4 and ADAMTS5 aggrecanases in osteoarthritis: a review.
Clinical and Experimental Rheumatology
26
(1)
, pp. 139-145.
|
|
|
|
Li, S., Cao, J., Shi, Z., Chen, J., Zhang, Z., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661
2008.
Promotion of the articular cartilage proteoglycan degradation by T-2 toxin and selenium protective effect.
Journal of Zhejiang University-Science B
9
(1)
, pp. 22-33.
10.1631/jzus.B071322
|
|
|
|
McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Serpi, Michaela ORCID: https://orcid.org/0000-0002-6162-7910, Bibbo, Rita, Roberts, Helen Christina, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Gibert, Ana Torrent and Verson, Carlos Raul Alaez
2008.
Phosphate prodrugs derived from N-acetylglucosamine have enhanced chondroprotective activity in explant cultures and represent a new lead in antiosteoarthritis drug discovery.
Journal of Medicinal Chemistry
51
(18)
, pp. 5807-5812.
10.1021/jm800594c
|
|
|
|
Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Hayes, Anthony Joseph, Tudor, D., Nowell, Mari Ann and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877
2008.
Chondroitin sulphate motifs as biomarkers for the stem/progenitor cell niche in musculoskeletal tissues.
European Cells and Materials
16
(Supp 2)
, p. 47.
|
|
|
|
Powell, Alison J., Little, Christopher B. and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877
2007.
Low molecular weight isoforms of the aggrecanases are responsible for the cytokine-induced proteolysis of aggrecan in a porcine chondrocyte culture system.
Arthritis & Rheumatism
56
(9)
, pp. 3010-3019.
10.1002/art.22818
|
|
|
|
Bondeson, Jan, Lauder, Sarah Nicol, Wainwright, Shane Daniel, Amos, Nick, Evans, A., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Feldmann, M. and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661
2007.
Adenoviral gene transfer of the endogenous inhibitor IkappaBalpha into human osteoarthritis synovial fibroblasts demonstrates that several matrix metalloproteinases and aggrecanases are nuclear factor-kappaB-dependent.
The Journal of Rheumatology
34
(3)
, pp. 523-533.
|
|
|
|
Gendron, C., Kashiwagi, M, Lim, N. H., Enghild, J. J., Thogersen, I. B., Hughes, Clare ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Nagase, H.
2007.
Proteolytic activities of human ADAMTS-5: Comparative studies wth ADAMTS - 4.
Journal of Biological Chemistry
282
(25)
, pp. 18294-18306.
10.1074/jbc.M701523200
|
|
|
|
Gealy, Elizabeth Claire, Kerr, Briedgeen, Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Tudor, Debbie, Hayes, Anthony Joseph, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 and Ralphs, James Robert ORCID: https://orcid.org/0000-0002-5367-0732
2007.
Differential expression of the keratan sulphate proteoglycan, keratocan, during chick corneal embryogenesis.
Histochemistry and Cell Biology
128
(6)
, pp. 551-555.
10.1007/s00418-007-0332-4
|
|
|
|
Jones, Aled R.C., Gleghorn, Jason P., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Fitz, Lori J., Zollner, Richard, Wainwright, Shane Daniel, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Morris, Elisabeth A., Bonassar, Lawrence J. and Flannery, Carl R.
2007.
Binding and localization of recombinant lubricin to articular cartilage surfaces.
Journal of Orthopaedic Research
25
(3)
, pp. 283-292.
10.1002/jor.20325
|
|
|
|
Gendron, Christi, Kashiwagi, Masahide, Lim, Ngee Han, Enghild, Jan J., Thogersen, Ida B., Hughes, Clare ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Nagase, Hideaki
2007.
Proteolytic activities of human ADAMTS-5. comparative studies with human ADAMTS-4 [Erratum].
World Journal of Biological Chemistry
282
(38)
, p. 28296.
|
|
|
|
Bondeson, Jan, Wainwright, Shane Daniel, Lauder, Sarah Nicol, Amos, Nick and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877
2006.
The role of synovial macrophages and macrophage-produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis.
Arthritis Research and Therapy
8
(6)
, pp. 187-199.
10.1186/ar2099
|
|
|
|
Hayashida, Yasutaka, Akama, Tomoya O., Beecher, Nicola, Lewis, Philip ORCID: https://orcid.org/0000-0002-3353-0708, Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538, Kerr, Briedgeen, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Tanigami, Akira, Nakayama, Jun, Fukada, Michiko N., Tano, Yasuo, Nishida, Kohji and Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120
2006.
Matrix morphogenesis in cornea is mediated by the modification of keratan sulfate by GlcNAc 6-O-sulfotransferase.
PNAS
103
(36)
, pp. 13333-13338.
10.1073/pnas.0605441103
|
|
|
|
Grau, Sandra, Richards, Peter J., Kerr, Briedgeen, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Junker, Uwe, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Clausen, Tim and Ehrmann, Michael ORCID: https://orcid.org/0000-0002-1927-260X
2006.
The role of human HtrA1 in arthritic disease.
The Journal of Biological Chemistry
281
(10)
, pp. 6124-6129.
10.1074/jbc.M500361200
|
|
|
|
Little, C. B., Flannery, C. R., Hughes, C. E. ORCID: https://orcid.org/0000-0003-4726-5877, Goodship, A. and Caterson, B. ORCID: https://orcid.org/0000-0001-6016-0661
2005.
Cytokine induced metalloproteinase expression and activity does not correlate with focal susceptibility of articular cartilage to degeneration.
Osteoarthritis and Cartilage
13
(2)
10.1016/j.joca.2004.10.014
|
|
|
|
Innes, John F., Little, Chris B., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661
2005.
Products resulting from cleavage of the interglobular domain of aggrecan in samples of synovial fluid collected from dogs with early- and late-stage osteoarthritis.
American Journal of Veterinary Research
66
(10)
, pp. 1679-1685.
10.2460/ajvr.2005.66.1679
|
|
|
|
Hayes, Anthony Joseph, Tudor, D., Nowell, M. A., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661
2005.
Novel chondroitin sulphation motifs as putative biomarkers of articular cartilage chondroprogenitor cells [Abstract].
European Cells and Materials
10
(Supp 2)
, p. 72.
|
|
|
|
Kashiwagi, M., Enghild, J. J., Gendron, Christi, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Itoh, Y. and Nagase, H.
2004.
Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing.
Journal of Biological Chemistry
279
(11)
, pp. 10109-10119.
10.1074/jbc.M312123200
|
|
|
|
Kashiwagi, Masahide, Enghild, Jan J., Gendron, Christi, Hughes, Clare ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Itoh, Yoshifumi and Nagase, Hideaki
2004.
Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing [Erratum].
World Journal of Biological Chemistry
279
(21)
, p. 22786.
|
|
|
|
Harris, Claire Louise, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Goodfellow, Ian, Evans, David J., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676
2003.
Generation of anti-complement 'prodrugs': cleavable reagents for specific delivery of complement regulators to disease sites.
The Journal of Biological Chemistry
278
(38)
, pp. 36068-36076.
10.1074/jbc.M306351200
|
|
|
|
Dart, A. J., Little, C. B., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Chu, Q., Dowling, B. A., Hodgson, D. R., Rose, R. J. and Johnson, K. A.
2003.
Recombinant equine growth hormone administration: effects on synovial fluid biomarkers and cartilage metabolism in horses.
Equine Veterinary Journal
35
(3)
, pp. 302-307.
10.2746/042516403776148165
|
|
|
|
Gendron, Christi, Kashiwagi, Masahide, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Nagase, Hideaki
2003.
TIMP-3 inhibits aggrecanase-mediated glycosaminoglycan release from cartilage explants stimulated by catabolic factors.
FEBS Letters
555
(3)
, pp. 431-436.
10.1016/S0014-5793(03)01295-X
|
|
|
|
Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Little, Christopher B. and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661
2003.
Measurement of aggrecanase-generated interglobular domain catabolites in the medium and extracts of cartilage explants using Western blot analysis.
Winyard, Paul G. and Willoughby, Derek A., eds.
Inflammation Protocols,
Vol. 225.
Methods in Molecular Biology,
Humana Press,
pp. 89-98.
(10.1385/1-59259-374-7:89)
|
|
|
|
Rees, Sarah Geraldine, Davies, Janet Rosemary, Tudor, Debbie, Flannery, Carl Ralph, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Dent, Colin Michael and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661
2002.
Immunolocalisation and expression of proteoglycan 4 (cartilage superficial zone proteoglycan) in tendon.
Matrix biology
21
(7)
, pp. 593-602.
10.1016/S0945-053X(02)00056-2
|
|
|
|
Curtis, Clare L., Rees, Sarah G., Little, Chris B., Flannery, Carl R., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Wilson, Chris, Dent, Colin M., Otterness, Ivan G., Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612 and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661
2002.
Pathologic indicators of degradation and inflammation in human osteoarthritic cartilage are abrogated by exposure to n-3 fatty acids [RETRACTED].
Arthritis & Rheumatism
46
(6)
, pp. 1544-1553.
10.1002/art.10305
|
|
|
|
Little, C. B., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Jones, Simon A., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Flannery, Carl A.
2002.
Cyclosporin A inhibition of aggrecanase-mediated proteoglycan catabolism in articular cartilage.
Arthritis and Rheumatism -
46
(1)
, pp. 124-129.
|
|
|
|
Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Siegler, Veronique, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661
2002.
Keratan sulphate levels during development of the embryonic avian cornea.
Investigative Ophthalmology and Visual Science
43
(E-Abst)
|
|
|
|
Curtis, Clare Louise, Rees, Sarah G., Cramp, Joanna, Flannery, Carl R., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Little, Chris B., Williams, Rhys, Wilson, Chris, Dent, Colin M., Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612 and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661
2002.
Effects of n-3 fatty acids on cartilage metabolism [RETRACTED].
Proceedings of the Nutrition Society
61
(3)
, pp. 381-389.
10.1079/PNS2002174
|
|
|
|
Little, Christopher B., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Curtis, Clare L., Janusz, Mike J., Bohne, Richard, Wang-Weigand, Sherry, Taiwo, Yetunde O., Mitchell, Peter G., Otterness, Ivan G., Flannery, Carl R. and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661
2002.
Matrix metalloproteinases are involved in C-terminal and interglobular domain processing of cartilage aggrecan in late stage cartilage degradation.
Matrix biology
21
(3)
, pp. 271-288.
10.1016/S0945-053X(02)00004-5
|
|
|
|
Little, C. B., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Otterness, I. G. and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661
2001.
Species specificity of neoepitope antibodies to aggrecanase and MMP-generated sequences in the interglobular domain of aggrecan [Poster Abstract].
International Journal of Experimental Pathology
82
(6)
, A12.
10.1046/j.1365-2613.2001.82_6am.x
|
|
|
|
Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Flannery, Carl R., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 and Little, Chris B.
2000.
Mechanisms involved in cartilage proteoglycan catabolism.
Matrix Biology
19
(4)
, pp. 333-344.
10.1016/S0945-053X(00)00078-0
|
|
|
|
Curtis, Clare L., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Flannery, C. R., Little, Chris B., Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612 and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661
2000.
n-3 Fatty Acids Specifically Modulate Catabolic Factors Involved in Articular Cartilage Degradation.
Journal of Biological Chemistry
275
(2)
, pp. 721-724.
10.1074/jbc.275.2.721
|
|
|
|
Flannery, Carl R., Little, Chris B., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Curtis, Clare L., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Jones, Simon A.
2000.
IL-6 and its soluble receptor augment aggrecanase-mediated proteoglycan catabolism in articular cartilage.
Matrix biology
19
(6)
, pp. 549-553.
10.1016/S0945-053X(00)00111-6
|
|
|
|
Rees, Sarah G., Flannery, Carl R., Little, Chris B., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Dent, Colin M.
2000.
Catabolism of aggrecan, decorin and biglycan in tendon.
Biochemical Journal
350
(1)
, pp. 181-188.
10.1042/0264-6021:3500181
|
|
|
Cardiff University Information Services