Bains, Kiranjit K. ORCID: https://orcid.org/0000-0001-6617-5768, Ashworth, Sean, Koudouna, Elena ORCID: https://orcid.org/0000-0002-9959-4667, Young, Robert D. ORCID: https://orcid.org/0000-0002-8300-8002, Hughes, Clare E. ORCID: https://orcid.org/0000-0003-4726-5877 and Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 2023. Chondroitin sulphate/dermatan sulphate proteoglycans: potential regulators of corneal stem/progenitor cell phenotype in vitro. International Journal of Molecular Sciences 24 (3) , 2095. 10.3390/ijms24032095 |
Mutoji, Kazadi N., Sun, Mingxia, Elliott, Garrett, Moreno, Isabel Y., Hughes, Clare ORCID: https://orcid.org/0000-0003-4726-5877, Gesteira, Tarsis F. and Coulson-Thomas, Vivien J. 2021. Extracellular matrix deposition and remodeling after corneal alkali burn in mice. International Journal of Molecular Sciences 22 (11) , 5708. 10.3390/ijms22115708 |
Allaith, S., Tew, S. R., Hughes, C. E. ORCID: https://orcid.org/0000-0003-4726-5877, Clegg, P. D., Canty-Laird, E. G. and Comerford, E. J. 2021. Characterisation of key proteoglycans in the cranial cruciate ligaments (CCLs) from two dog breeds with different predispositions to CCL disease and rupture. The Veterinary Journal 272 , 105657. 10.1016/j.tvjl.2021.105657 |
Ashworth, Sean, Harrington, Jodie, Hammond, Greg M., Bains, Kiranjit K. ORCID: https://orcid.org/0000-0001-6617-5768, Koudouna, Elena ORCID: https://orcid.org/0000-0002-9959-4667, Hayes, Anthony J., Ralphs, James R. ORCID: https://orcid.org/0000-0002-5367-0732, Regini, Justyn W. ORCID: https://orcid.org/0000-0001-6149-5893, Young, Robert D. ORCID: https://orcid.org/0000-0002-8300-8002, Hayashi, Ryuhei, Nishida, Kohji, Hughes, Clare E. ORCID: https://orcid.org/0000-0003-4726-5877 and Quantock, Andrew J. ORCID: https://orcid.org/0000-0002-2484-3120 2021. Chondroitin sulfate as a potential modulator of the stem cell niche in cornea. Frontiers in Cell and Developmental Biology 8 , 567358. 10.3389/fcell.2020.567358 |
Nandadasa, Sumeda, Szafron, Jason M., Pathak, Vai, Murtada, Sae-Il, Kraft, Caroline M., O'Donnell, Anna, Norvik, Christian, Hughes, Clare ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Domowicz, Miriam S., Schwartz, Nancy B., Tran-Lundmark, Karin, Veigl, Martina, Sedwick, David, Philipson, Elliot H., Humphrey, Jay D. and Apte, Suneel S. 2020. Vascular dimorphism ensured by regulated proteoglycan dynamics favors rapid umbilical artery closure at birth. eLife 9 , e60683. 10.7554/eLife.60683 |
Powell, Alison, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Hughes, Clare ORCID: https://orcid.org/0000-0003-4726-5877, Paul, Alison ORCID: https://orcid.org/0000-0002-7653-9964, James, Craig ORCID: https://orcid.org/0000-0002-0569-182X, Hopkins, Stephen, Mansour, Omar and Griffiths, Peter 2017. Do model polymer therapeutics sufficiently diffuse through articular cartilage to be a viable therapeutic route? Journal of Drug Targeting 25 (9-10) , pp. 919-926. 10.1080/1061186X.2017.1378660 |
Hayes, Anthony Joseph, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Smith, Susan M., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Little, Christopher B. and Melrose, James 2016. The CS sulphation motifs 4C3, 7D4, 3B3[-]; and perlecan identify stem cell populations and niches, activated progenitor cells and transitional tissue development in the fetal human elbow. Stem Cells and Development 25 (11) , pp. 836-847. 10.1089/scd.2016.0054 |
Bascoul-Colombo, Cecile, Garaiova, Iveta, Plummer, Sue F., Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hughes, Clare E. ORCID: https://orcid.org/0000-0003-4726-5877 2016. Glucosamine hydrochloride but not chondroitin sulfate prevents cartilage degradation and inflammation induced by interleukin-1α in bovine cartilage explants. Cartilage 7 (1) , pp. 70-81. 10.1177/1947603515603762 |
Esa, Adam, Archer, C. W., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hughes, Clare E. ORCID: https://orcid.org/0000-0003-4726-5877 2015. Investigating the role of Wnt antagonist protein Dkk-1 in the pathogenesis of osteoarthritis [Abstract]. International Journal of Experimental Pathology 96 (2) , A29-A29. 10.1111/iep.12125 |
Chen, Jinghong, Luo, Mingxiu, Wang, Wei, Zhang, Zentie, Duance, Victor Colin ORCID: https://orcid.org/0000-0002-7555-2016, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Cao, Junling 2015. Altered proteolytic activity and expression of mmps and aggrecanases and their inhibitors in Kashin-Beck disease. Journal of Orthopaedic Research 33 (1) , pp. 47-55. 10.1002/jor.22708 |
Luo, M., Chen, J., Li, S., Sun, H., Zhang, Z., Fu, Q., Li, J., Wang, J., Hughes, C. E. ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, B. ORCID: https://orcid.org/0000-0001-6016-0661 and Cao, J. 2014. Changes in the metabolism of chondroitin sulfate glycosaminoglycans in articular cartilage from patients with Kashin-Beck disease. Osteoarthritis and Cartilage 22 (7) , pp. 986-995. 10.1016/j.joca.2014.05.012 |
Shu, Cindy, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Smith, Susan M., Smith, Margaret M., Hayes, Anthony Joseph, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Little, Christopher B. and Melrose, James 2013. The ovine newborn and human foetal intervertebral disc contain perlecan and aggrecan variably substituted with native 7D4 CS sulphation motif: spatiotemporal immunolocalisation and co-distribution with Notch-1 in the human foetal disc. Glycoconjugate Journal 30 (7) , pp. 717-725. 10.1007/s10719-013-9475-9 |
Guan, Fang, Li, Siyuan, Wang, Zhi-lun, Yang, Haojie, Xue, Senghai, Wang, Wei, Song, Daiqing, Zhou, Xiaorong, Zhou, Wang, Chen, Jing-hong, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 2013. Histopathology of chondronecrosis development in knee articular cartilage in a rat model of Kashin-Beck disease using T-2 toxin and selenium deficiency conditions. Rheumatology International 33 (1) , pp. 157-166. 10.1007/s00296-011-2335-7 |
Li, Siyuan, Hayes, Anthony Joseph, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 2013. The effect of beta-xylosides on the chondrogenic differentiation of mesenchymal stem cells. Histochemistry and Cell Biology 139 (1) , pp. 59-74. 10.1007/s00418-012-1017-1 |
Bondeson, Jan, Wainwright, Shane Daniel, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 2013. ADAMTS4. Rawlings, Neil D. and Salvesen, Guy, eds. Handbook of Proteolytic Enzymes. 3rd ed., Vol. 1. London: Academic Press, pp. 1166-1173. (10.1016/B978-0-12-382219-2.00262-3) |
Bondeson, Jan, Wainwright, Shane Daniel, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 2013. ADAMTS5. Rawlings, Neil D. and Salvesen, G., eds. Handbook of Proteolytic Enzymes. 3rd ed., Vol. 1. London: Academic Press, pp. 1174-1180. (10.1016/B978-0-12-382219-2.00263-5) |
Melrose, James, Isaacs, Marc D., Smith, Susan M., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Little, Christopher B., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hayes, Anthony Joseph 2012. Chondroitin sulphate and heparan sulphate sulphation motifs and their proteoglycans are involved in articular cartilage formation during human foetal knee joint development. Histochemistry and Cell Biology 138 (3) , pp. 461-475. 10.1007/s00418-012-0968-6 |
Serpi, Michaela ORCID: https://orcid.org/0000-0002-6162-7910, Bibbo, Rita, Rat, Stephanie, Roberts, Helen Christina, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Alcaraz, María José, Gibert, Anna Torrent, Verson, Carlos Raul Alaez and McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X 2012. Novel phosphoramidate prodrugs of N-Acetyl-(d)-Glucosamine with antidegenerative activity on bovine and human cartilage explants. Journal of Medicinal Chemistry 55 (10) , pp. 4629-4639. 10.1021/jm300074y |
Li, Siyuan, Cao, Junling, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 2012. Proteoglycan metabolism, cell death and Kashin-Beck Disease. Glycoconjugate Journal 29 (5-6) , pp. 241-248. 10.1007/s10719-012-9421-2 |
Liles, Melody, Palka, Barbara Paulina, Harris, Anthony, Kerr, Briedgeen, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 2010. Differential relative sulfation of keratan sulfate glycosaminoglycan in the chick cornea during embryonic development. Investigative Ophthalmology and Visual Science 51 (3) , pp. 1365-1372. 10.1167/iovs.09-4004 |
Bondeson, Jan, Blom, Arjen B., Wainwright, Shane Daniel, Hughes, Clare ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and van den Berg, Wim B. 2010. The role of synovial macrophages and macrophage-produced mediators in driving inflammatory and destructive responses in osteoarthritis. Arthritis & Rheumatism 62 (3) , pp. 647-657. 10.1002/art.27290 |
Zhang, A., Cao, J. L., Yang, B., Chen, J. H., Zhang, Z. T., Li, Siyuan, Fu, Q., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 2010. Effects of moniliformin and selenium on human articular cartilage metabolism and their potential relationships to the pathogenesis of Kashin-Beck disease. Journal of Zhejiang University-Science B 11 (3) , pp. 200-208. 10.1631/jzus.B0900074 |
Hurst, S., Zainal, Z., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 and Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612 2010. Dietary fatty acids and arthritis. Prostaglandins Leukotrienes & Essential Fatty Acids 82 (4-6) , pp. 315-318. 10.1016/j.plefa.2010.02.008 |
Zainal, Z., Longman, Andrea Jane, Hurst, S., Duggan, K., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 and Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612 2009. Relative efficacies of omega-3 polyunsaturated fatty acids in reducing expression of key proteins in a model system for studying osteoarthritis. Osteoarthritis and Cartilage 17 (7) , pp. 896-905. 10.1016/j.joca.2008.12.009 |
Clarkin, C. E., Cheung, I., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Poulet, B., Edwards, J., Wheeler-Jones, C. P. D, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Pitsillides, A. A. 2009. Phenotypic plasticity of superficial zone chondrocytes is revealed by increased glycosaminoglycan release and a unique angiogenic secretory profile from neo-cartilage grafts [Abstract]. International Journal of Experimental Pathology 90 (2) , A103-A104. 10.1111/j.1365-2613.2009.00644.x |
Roberts, Helen Christina, Serpi, M., Bibbo, R., McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Gilbert, A. T., Verson, C. R. A., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 2009. Chemically modified glucosamine inhibits the release of proteoglycan in a model system of articular cartilage degradation. International Journal of Experimental Pathology 90 (1) , A78-A79. |
Roberts, Helen Christina, Serpi, M., Bibbo, R., McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Gilbert, A., Verson, C. R. A., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 2009. Chemically modified glucosamine inhibits the release of proteoglycan in a model system of articular cartilage degradation [Abstract]. International Journal of Experimental Pathology 90 (1) , A78-A79. 10.1111/j.1365-2613.2008.00612.x |
Rees, S. G., Waggett, A. D., Kerr, Briedgeen, Probert, J., Gealy, Elizabeth Claire, Dent, C. M., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 2009. Immunolocalisation and expression of keratocan in tendon. Osteoarthritis and Cartilage 17 (2) , pp. 276-279. 10.1016/j.joca.2008.07.007 |
Zainal, Z., Longman, Andrea Jane, Hurst, S., Duggan, K., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Harwood, John ORCID: https://orcid.org/0000-0003-2377-2612 2009. Modification of Palm Oil for Anti-Inflammatory Nutraceutical Properties. Lipids 44 (7) , pp. 581-592. 10.1007/s11745-009-3304-8 |
Melrose, James, Fuller, Emily S., Roughley, Peter J., Smith, Margaret M., Kerr, Briedgeen, Hughes, Clare E ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Little, Christopher B, 2008. Fragmentation of decorin, biglycan, lumican and keratocan is elevated in degenerate human meniscus, knee and hip articular cartilages compared with age-matched macroscopically normal and control tissues. Arthritis Research & Therapy 10 (4) , R79. 10.1186/ar2453 |
Cao, J., Li, S., Shi, Z., Yue, Y., Sun, J., Chen, J., Fu, Q., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 2008. Articular cartilage metabolism in patients with Kashin-Beck Disease: an endemic osteoarthropathy in China. Osteoarthritis and Cartilage 16 (6) , pp. 680-8. 10.1016/j.joca.2007.09.002 |
Hayes, Anthony Joseph, Tudor, Debbie, Nowell, Mari Ann, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 2008. Chondroitin sulfate sulfation motifs as putative biomarkers for isolation of articular cartilage progenitor cells. Journal of Histochemistry & Cytochemistry 56 (2) , pp. 125-38. 10.1369/jhc.7A7320.2007 |
Akhtar, S., Kerr, Briedgeen, Hayes, Anthony Joseph, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Meek, Keith Michael ORCID: https://orcid.org/0000-0002-9948-7538 and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 2008. Immunochemical localisation of keratan sulphate proteoglycans in cornea, sclera and limbus using a keratanase generated neoepitope monoclonal antibody. Investigative Ophthalmology and Visual Science 49 (6) , pp. 2424-2431. 10.1167/iovs.06-1498 |
Bondeson, Jan, Wainwright, Shane Daniel, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 2008. The regulation of ADAMTS4 and ADAMTS5 aggrecanases in osteoarthritis: a review. Clinical and Experimental Rheumatology 26 (1) , pp. 139-145. |
Li, S., Cao, J., Shi, Z., Chen, J., Zhang, Z., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 2008. Promotion of the articular cartilage proteoglycan degradation by T-2 toxin and selenium protective effect. Journal of Zhejiang University-Science B 9 (1) , pp. 22-33. 10.1631/jzus.B071322 |
McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Serpi, Michaela ORCID: https://orcid.org/0000-0002-6162-7910, Bibbo, Rita, Roberts, Helen Christina, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Gibert, Ana Torrent and Verson, Carlos Raul Alaez 2008. Phosphate prodrugs derived from N-acetylglucosamine have enhanced chondroprotective activity in explant cultures and represent a new lead in antiosteoarthritis drug discovery. Journal of Medicinal Chemistry 51 (18) , pp. 5807-5812. 10.1021/jm800594c |
Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Hayes, Anthony Joseph, Tudor, D., Nowell, Mari Ann and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 2008. Chondroitin sulphate motifs as biomarkers for the stem/progenitor cell niche in musculoskeletal tissues. European Cells and Materials 16 (Supp 2) , p. 47. |
Powell, Alison J., Little, Christopher B. and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 2007. Low molecular weight isoforms of the aggrecanases are responsible for the cytokine-induced proteolysis of aggrecan in a porcine chondrocyte culture system. Arthritis & Rheumatism 56 (9) , pp. 3010-3019. 10.1002/art.22818 |
Bondeson, Jan, Lauder, Sarah Nicol, Wainwright, Shane Daniel, Amos, Nick, Evans, A., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Feldmann, M. and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 2007. Adenoviral gene transfer of the endogenous inhibitor IkappaBalpha into human osteoarthritis synovial fibroblasts demonstrates that several matrix metalloproteinases and aggrecanases are nuclear factor-kappaB-dependent. The Journal of Rheumatology 34 (3) , pp. 523-533. |
Gendron, C., Kashiwagi, M, Lim, N. H., Enghild, J. J., Thogersen, I. B., Hughes, Clare ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Nagase, H. 2007. Proteolytic activities of human ADAMTS-5: Comparative studies wth ADAMTS - 4. Journal of Biological Chemistry 282 (25) , pp. 18294-18306. 10.1074/jbc.M701523200 |
Gealy, Elizabeth Claire, Kerr, Briedgeen, Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Tudor, Debbie, Hayes, Anthony Joseph, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 and Ralphs, James Robert ORCID: https://orcid.org/0000-0002-5367-0732 2007. Differential expression of the keratan sulphate proteoglycan, keratocan, during chick corneal embryogenesis. Histochemistry and Cell Biology 128 (6) , pp. 551-555. 10.1007/s00418-007-0332-4 |
Jones, Aled R.C., Gleghorn, Jason P., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Fitz, Lori J., Zollner, Richard, Wainwright, Shane Daniel, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Morris, Elisabeth A., Bonassar, Lawrence J. and Flannery, Carl R. 2007. Binding and localization of recombinant lubricin to articular cartilage surfaces. Journal of Orthopaedic Research 25 (3) , pp. 283-292. 10.1002/jor.20325 |
Gendron, Christi, Kashiwagi, Masahide, Lim, Ngee Han, Enghild, Jan J., Thogersen, Ida B., Hughes, Clare ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Nagase, Hideaki 2007. Proteolytic activities of human ADAMTS-5. comparative studies with human ADAMTS-4 [Erratum]. World Journal of Biological Chemistry 282 (38) , p. 28296. |
Bondeson, Jan, Wainwright, Shane Daniel, Lauder, Sarah Nicol, Amos, Nick and Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 2006. The role of synovial macrophages and macrophage-produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis. Arthritis Research and Therapy 8 (6) , pp. 187-199. 10.1186/ar2099 |
Hayashida, Yasutaka, Akama, Tomoya O., Beecher, Nicola, Lewis, Philip ORCID: https://orcid.org/0000-0002-3353-0708, Young, Robert David ORCID: https://orcid.org/0000-0002-8300-8002, Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538, Kerr, Briedgeen, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Tanigami, Akira, Nakayama, Jun, Fukada, Michiko N., Tano, Yasuo, Nishida, Kohji and Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120 2006. Matrix morphogenesis in cornea is mediated by the modification of keratan sulfate by GlcNAc 6-O-sulfotransferase. PNAS 103 (36) , pp. 13333-13338. 10.1073/pnas.0605441103 |
Grau, Sandra, Richards, Peter J., Kerr, Briedgeen, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Junker, Uwe, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Clausen, Tim and Ehrmann, Michael ORCID: https://orcid.org/0000-0002-1927-260X 2006. The role of human HtrA1 in arthritic disease. The Journal of Biological Chemistry 281 (10) , pp. 6124-6129. 10.1074/jbc.M500361200 |
Little, C. B., Flannery, C. R., Hughes, C. E. ORCID: https://orcid.org/0000-0003-4726-5877, Goodship, A. and Caterson, B. ORCID: https://orcid.org/0000-0001-6016-0661 2005. Cytokine induced metalloproteinase expression and activity does not correlate with focal susceptibility of articular cartilage to degeneration. Osteoarthritis and Cartilage 13 (2) 10.1016/j.joca.2004.10.014 |
Innes, John F., Little, Chris B., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 2005. Products resulting from cleavage of the interglobular domain of aggrecan in samples of synovial fluid collected from dogs with early- and late-stage osteoarthritis. American Journal of Veterinary Research 66 (10) , pp. 1679-1685. 10.2460/ajvr.2005.66.1679 |
Hayes, Anthony Joseph, Tudor, D., Nowell, M. A., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 2005. Novel chondroitin sulphation motifs as putative biomarkers of articular cartilage chondroprogenitor cells [Abstract]. European Cells and Materials 10 (Supp 2) , p. 72. |
Kashiwagi, M., Enghild, J. J., Gendron, Christi, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Itoh, Y. and Nagase, H. 2004. Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing. Journal of Biological Chemistry 279 (11) , pp. 10109-10119. 10.1074/jbc.M312123200 |
Kashiwagi, Masahide, Enghild, Jan J., Gendron, Christi, Hughes, Clare ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Itoh, Yoshifumi and Nagase, Hideaki 2004. Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing [Erratum]. World Journal of Biological Chemistry 279 (21) , p. 22786. |
Harris, Claire Louise, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Williams, Anwen Sian ORCID: https://orcid.org/0000-0001-6118-020X, Goodfellow, Ian, Evans, David J., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2003. Generation of anti-complement 'prodrugs': cleavable reagents for specific delivery of complement regulators to disease sites. The Journal of Biological Chemistry 278 (38) , pp. 36068-36076. 10.1074/jbc.M306351200 |
Dart, A. J., Little, C. B., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Chu, Q., Dowling, B. A., Hodgson, D. R., Rose, R. J. and Johnson, K. A. 2003. Recombinant equine growth hormone administration: effects on synovial fluid biomarkers and cartilage metabolism in horses. Equine Veterinary Journal 35 (3) , pp. 302-307. 10.2746/042516403776148165 |
Gendron, Christi, Kashiwagi, Masahide, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Nagase, Hideaki 2003. TIMP-3 inhibits aggrecanase-mediated glycosaminoglycan release from cartilage explants stimulated by catabolic factors. FEBS Letters 555 (3) , pp. 431-436. 10.1016/S0014-5793(03)01295-X |
Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Little, Christopher B. and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 2003. Measurement of aggrecanase-generated interglobular domain catabolites in the medium and extracts of cartilage explants using Western blot analysis. Winyard, Paul G. and Willoughby, Derek A., eds. Inflammation Protocols, Vol. 225. Methods in Molecular Biology, Humana Press, pp. 89-98. (10.1385/1-59259-374-7:89) |
Rees, Sarah Geraldine, Davies, Janet Rosemary, Tudor, Debbie, Flannery, Carl Ralph, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Dent, Colin Michael and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 2002. Immunolocalisation and expression of proteoglycan 4 (cartilage superficial zone proteoglycan) in tendon. Matrix biology 21 (7) , pp. 593-602. 10.1016/S0945-053X(02)00056-2 |
Curtis, Clare L., Rees, Sarah G., Little, Chris B., Flannery, Carl R., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Wilson, Chris, Dent, Colin M., Otterness, Ivan G., Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612 and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 2002. Pathologic indicators of degradation and inflammation in human osteoarthritic cartilage are abrogated by exposure to n-3 fatty acids [RETRACTED]. Arthritis & Rheumatism 46 (6) , pp. 1544-1553. 10.1002/art.10305 |
Little, C. B., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Jones, Simon A., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Flannery, Carl A. 2002. Cyclosporin A inhibition of aggrecanase-mediated proteoglycan catabolism in articular cartilage. Arthritis and Rheumatism - 46 (1) , pp. 124-129. |
Quantock, Andrew James ORCID: https://orcid.org/0000-0002-2484-3120, Siegler, Veronique, Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 2002. Keratan sulphate levels during development of the embryonic avian cornea. Investigative Ophthalmology and Visual Science 43 (E-Abst) |
Curtis, Clare Louise, Rees, Sarah G., Cramp, Joanna, Flannery, Carl R., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Little, Chris B., Williams, Rhys, Wilson, Chris, Dent, Colin M., Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612 and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 2002. Effects of n-3 fatty acids on cartilage metabolism [RETRACTED]. Proceedings of the Nutrition Society 61 (3) , pp. 381-389. 10.1079/PNS2002174 |
Little, Christopher B., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Curtis, Clare L., Janusz, Mike J., Bohne, Richard, Wang-Weigand, Sherry, Taiwo, Yetunde O., Mitchell, Peter G., Otterness, Ivan G., Flannery, Carl R. and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 2002. Matrix metalloproteinases are involved in C-terminal and interglobular domain processing of cartilage aggrecan in late stage cartilage degradation. Matrix biology 21 (3) , pp. 271-288. 10.1016/S0945-053X(02)00004-5 |
Little, C. B., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Otterness, I. G. and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 2001. Species specificity of neoepitope antibodies to aggrecanase and MMP-generated sequences in the interglobular domain of aggrecan [Poster Abstract]. International Journal of Experimental Pathology 82 (6) , A12. 10.1046/j.1365-2613.2001.82_6am.x |
Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661, Flannery, Carl R., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877 and Little, Chris B. 2000. Mechanisms involved in cartilage proteoglycan catabolism. Matrix Biology 19 (4) , pp. 333-344. 10.1016/S0945-053X(00)00078-0 |
Curtis, Clare L., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Flannery, C. R., Little, Chris B., Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612 and Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 2000. n-3 Fatty Acids Specifically Modulate Catabolic Factors Involved in Articular Cartilage Degradation. Journal of Biological Chemistry 275 (2) , pp. 721-724. 10.1074/jbc.275.2.721 |
Flannery, Carl R., Little, Chris B., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Curtis, Clare L., Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Jones, Simon A. 2000. IL-6 and its soluble receptor augment aggrecanase-mediated proteoglycan catabolism in articular cartilage. Matrix biology 19 (6) , pp. 549-553. 10.1016/S0945-053X(00)00111-6 |
Rees, Sarah G., Flannery, Carl R., Little, Chris B., Hughes, Clare Elizabeth ORCID: https://orcid.org/0000-0003-4726-5877, Caterson, Bruce ORCID: https://orcid.org/0000-0001-6016-0661 and Dent, Colin M. 2000. Catabolism of aggrecan, decorin and biglycan in tendon. Biochemical Journal 350 (1) , pp. 181-188. 10.1042/0264-6021:3500181 |