Shephard, Alex P., Giles, Peter, Mbengue, Mariama, Alraies, Amr, Spary, Lisa K., Kynaston, Howard, Gurney, Mark J., Falcón-Pérez, Juan M., Royo, Félix, Tabi, Zsuzsanna, Parthimos, Dimitris, Errington, Rachel J., Clayton, Aled and Webber, Jason P.
2021.
Stroma-derived extracellular vesicle mRNA signatures inform histological nature of prostate cancer.
Journal of Extracellular Vesicles
10
(12)
, e12150.
10.1002/jev2.12150
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Langley, Ruth E., Gilbert, Duncan C., Duong, Trinh, Clarke, Noel W., Nankivell, Matthew, Rosen, Stuart D., Mangar, Stephen, Macnair, Archie, Sundaram, Subramanian Kanaga, Laniado, Marc E., Dixit, Sanjay, Madaan, Sanjeev, Manetta, Caroline, Pope, Alvan, Scrase, Christopher D., Mckay, Stephen, Muazzam, Iqtedar A., Collins, Gerald N., Worlding, Jane, Williams, Simon T., Paez, Edgar, Robinson, Angus, McFarlane, Jonathan, Deighan, John V., Marshall, John, Forcat, Silvia, Weiss, Melanie, Kockelbergh, Roger, Alhasso, Abdulla, Kynaston, Howard and Parmar, Mahesh 2021. Transdermal oestradiol for androgen suppression in prostate cancer: long-term cardiovascular outcomes from the randomised Prostate Adenocarcinoma Transcutaneous Hormone (PATCH) trial programme. Lancet 397 (10274) , pp. 581-591. 10.1016/S0140-6736(21)00100-8 |
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Bullock, Nicholas, Simpkin, Andrew, Fowler, Sarah, Varma, Murali, Kynaston, Howard and Narahari, Krishna
2019.
Pathological upgrading in prostate cancer treated with surgery in the United Kingdom: trends and risk factors from the British Association of Urological Surgeons Radical Prostatectomy Registry.
BMC Urology
19
(1)
, -.
10.1186/s12894-019-0526-9
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Bullock, Nicholas, Serag, Hosam and Kynaston, Howard 2019. Radical open surgery for management of extensive extra-prostatic benign prostatic hyperplasia. Journal of Clinical Urology 12 (5) , pp. 398-400. 10.1177/2051415818767181 |
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Burnell, Stephanie E. A., Spencer-Harty, Samantha, Howarth, Suzie, Bodger, Owen, Kynaston, Howard, Morgan, Claire and Doak, Shareen H.
2019.
Utilisation of the STEAP protein family in a diagnostic setting may provide a more comprehensive prognosis of prostate cancer.
PLoS ONE
14
(8)
, e0220456.
10.1371/journal.pone.0220456
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Foley, Kieran, Christian, Adam, Peaker, J., Marshall, Christopher, Spezi, Emiliano, Kynaston, Howard and Roberts, Stuart A.
2019.
Cyclo-oxygenase-2 expression is associated with mean standardised uptake value on 18F-fluorodeoxyglucose positron emission tomography in oesophageal adenocarcinoma.
British Journal of Radiology
92
(1099)
, 20180668.
10.1259/bjr.20180668
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Burnell, Stephanie E. A., Spencer-Harty, Samantha, Howarth, Suzie, Bodger, Owen, Kynaston, Howard, Morgan, Claire and Doak, Shareen H. 2018. STEAP2 knockdown reduces the invasive potential of prostate cancer cells. Scientific Reports 8 (1) , 6252. 10.1038/s41598-018-24655-x |
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Donovan, Jenny L., Young, Grace J., Walsh, Eleanor I., Metcalfe, Chris, Lane, J. Athene, Martin, Richard M., Tazewell, Marta K., Davis, Michael, Peters, Tim J., Turner, Emma L., Mills, Nicola, Khazragui, Hanan, Khera, Tarnjit K., Neal, David E., Hamdy, Freddie C., Bollina, Prasad, Catto, James, Doble, Andrew, Doherty, Alan, Gillatt, David, Gnanapragasam, Vincent, Holding, Peter, Hughes, Owen, Kockelbergh, Roger, Kynaston, Howard, Mason, Malcolm, Oxley, Jon, Paul, Alan, Paez, Edgar, Rosario, Derek J., Rowe, Edward and Staffurth, John 2018. A prospective cohort and extended comprehensive-cohort design provided insights about the generalizability of a pragmatic trial: the ProtecT prostate cancer trial. Journal of Clinical Epidemiology 96 , pp. 35-46. 10.1016/j.jclinepi.2017.12.019 |
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Jefferies, Matthew T., Cox, Adam C., Shorning, Boris Y., Meniel, Valerie, Griffiths, David, Kynaston, Howard G., Smalley, Matthew J. and Clarke, Alan R.
2017.
PTEN loss and activation of K-RAS and β-catenin cooperate to accelerate prostate tumourigenesis.
Journal of Pathology
243
(4)
, pp. 442-456.
10.1002/path.4977
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Jefferies, Matthew T., Pope, Christopher, Kynaston, Howard, Clarke, Alan R., Martin, Richard and Adams, Josephine 2017. Analysis of fascin-1 in relation to gleason risk classification and nuclear ets-related gene status of human prostate carcinomas: an immunohistochemical study of clinically annotated tumours from the Wales Cancer Bank. Biomarkers in Cancer 9 , pp. 1-8. 10.1177/1179299X17710944 |
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Gilbert, Duncan C., Duong, Trinh, Kynaston, Howard, Alhasso, Abdulla A., Cafferty, Fay H., Rosen, Stuart D., Kanaga-Sundaram, Subramanian, Dixit, Sanjay, Laniado, Marc, Madaan, Sanjeev, Collins, Gerald, Pope, Alvan, Welland, Andrew, Nankivell, Matthew, Wassersug, Richard, Parmar, Mahesh K. B., Langley, Ruth E. and Abel, Paul D. 2016. Quality-of-life outcomes from the Prostate Adenocarcinoma: TransCutaneous Hormones (PATCH) trial evaluating luteinising hormone-releasing hormone agonists versus transdermal oestradiol for androgen suppression in advanced prostate cancer. BJU International 119 (5) , pp. 667-675. 10.1111/bju.13687 |
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Coyle, Christopher, Cafferty, Fay H., Rowley, Samuel, MacKenzie, Mairead, Berkman, Lindy, Gupta, Sudeep, Pramesh, C S, Gilbert, Duncan, Kynaston, Howard, Cameron, David, Wilson, Richard H., Ring, Alistair and Langley, Ruth E. 2016. ADD-ASPIRIN: A phase III, double-blind, placebo controlled, randomised trial assessing the effects of aspirin on disease recurrence and survival after primary therapy in common non-metastatic solid tumours. Contemporary Clinical Trials 51 , pp. 56-64. 10.1016/j.cct.2016.10.004 |
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Donovan, Jenny L., Hamdy, Freddie C., Lane, J. Athene, Mason, Malcolm, Metcalfe, Chris, Walsh, Eleanor, Blazeby, Jane M., Peters, Tim J., Holding, Peter, Bonnington, Susan, Lennon, Teresa, Bradshaw, Lynne, Cooper, Deborah, Herbert, Phillipa, Howson, Joanne, Jones, Amanda, Lyons, Norma, Salter, Elizabeth, Thompson, Pauline, Tidball, Sarah, Blaikie, Jan, Gray, Catherine, Bollina, Prasad, Catto, James, Doble, Andrew, Doherty, Alan, Gillatt, David, Kockelbergh, Roger, Kynaston, Howard, Paul, Alan, Powell, Philip, Prescott, Stephen, Rosario, Derek J., Rowe, Edward, Davis, Michael, Turner, Emma L., Martin, Richard M. and Neal, David E.
2016.
Patient-reported outcomes after monitoring, surgery, or radiotherapy for prostate cancer.
New England Journal of Medicine
375
, pp. 1425-1437.
10.1056/NEJMoa1606221
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Hamdy, Freddie, Donovan, Jenny, Lane, J. Athene, Mason, Malcolm, Metcalfe, Chris, Holding, Peter, Davis, Michael, Peters, Tim J., Turner, Emma L., Martin, Richard M., Oxley, Jon, Robinson, Mary, Staffurth, John, Walsh, Eleanor, Bollina, Prasad, Catto, James, Doble, Andrew, Doherty, Alan, Gillatt, David, Kockelbergh, Roger, Kynaston, Howard, Paul, Alan, Powell, Philip, Prescott, Stephen, Rosario, Derek J., Rowe, Edward and Neal, David E.
2016.
10-Year outcomes after monitoring, surgery, or radiotherapy for localized prostate cancer.
New England Journal of Medicine
375
, pp. 1415-1424.
10.1056/NEJMoa1606220
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Langley, Ruth E., Kynaston, Howard, Alhasso, Abdulla A., Duong, Trinh, Paez, Edgar M., Jovic, Gordana, Scrase, Christopher D., Robertson, Andrew, Cafferty, Fay, Welland, Andrew, Carpenter, Robin, Honeyfield, Lesley, Abel, Richard L., Stone, Michael D., Parmar, Mahesh K.B. and Abel, Paul D.
2016.
A randomised comparison evaluating changes in bone mineral density in advanced prostate cancer: luteinising hormone-releasing hormone agonists versus transdermal oestradiol.
European Urology
69
(6)
, pp. 1016-1025.
10.1016/j.eururo.2015.11.030
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Weeks, Hoi, Sanders, Andrew, Kynaston, Howard and Jiang, Wen 2016. The association between WAVE1 and -3 and the ARP2/3 complex in PC 3 cells. Anticancer Research 36 (3) , pp. 1135-1142. |
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Moazzam, Muhammad, Ye, Lin, Sun, Ping-Hui, Kynaston, Howard and Jiang, Wen Guo 2015. Knockdown of WAVE3 impairs HGF induced migration and invasion of prostate cancer cells. Cancer Cell International 15 , 51. 10.1186/s12935-015-0203-3 |
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Webber, J. P., Spary, L. K., Sanders, A. J., Chowdhury, R., Jiang, W. G., Steadman, R., Wymant, J., Jones, A. T., Kynaston, H., Mason, M. D., Tabi, Z. and Clayton, A.
2015.
Differentiation of tumour-promoting stromal myofibroblasts by cancer exosomes.
Oncogene
34
(3)
, pp. 290-302.
10.1038/onc.2013.560
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Whiteland, Helen, Spencer-Harty, Samantha, Morgan, Claire, Kynaston, Howard, Thomas, David Hywel, Bose, Pradeep, Fenn, Neil, Lewis, Paul, Jenkins, Spencer and Doak, Shareen H. 2014. A role for STEAP2 in prostate cancer progression. Clinical & Experimental Metastasis 31 (8) , pp. 909-920. 10.1007/s10585-014-9679-9 |
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Jiang, Wen Guo, Ye, Lin, Sanders, Andrew James, Ruge, Fiona, Kynaston, Howard, Ablin, Richard J. and Mason, Malcolm David 2013. Prostate transglutaminase (TGase-4, TGaseP) enhances the adhesion of prostate cancer cells to extracellular matrix, the potential role of TGase-core domain. Journal of Translational Medicine 11 , 269. 10.1186/1479-5876-11-269 |
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Aboumarzouk, Omar, Hughes, Owen, Narahari, Krishna, Drewa, Tomasz, Chlosta, Piotr L. and Kynaston, Howard 2013. Safety and feasibility of Laparoscopic Radical Cystectomy for the treatment of bladder cancer. Journal of Endourology 27 (9) , pp. 1083-1095. 10.1089/end.2013.0084 |
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Langley, Ruth E., Cafferty, Fay H., Alhasso, Abdulla A., Rosen, Stuart D., Sundaram, Subramanian Kanaga, Freeman, Suzanne C., Pollock, Philip, Jinks, Rachel C., Godsland, Ian F., Kockelbergh, Roger, Clarke, Noel W., Kynaston, Howard, Parmar, Mahesh K. B. and Abel, Paul D. 2013. Cardiovascular outcomes in patients with locally advanced and metastatic prostate cancer treated with luteinising-hormone-releasing-hormone agonists or transdermal oestrogen: the randomised, phase 2 MRC PATCH trial (PR09). The Lancet Oncology 14 (4) , pp. 306-316. 10.1016/S1470-2045(13)70025-1 |
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Williams, Rebecca, Shorning, Boris, Datta, S., Kynaston, Howard and Clarke, Alan Richard 2012. Development and characterisation of a bladder cancer model [Poster]. BJU International 109 (S7) , p. 25. 10.1111/j.1464-410X.2012.11177.x |
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Shelley, Mike D., Jones, Gabriel, Cleves, Anne, Wilt, Timothy J., Mason, Malcolm David and Kynaston, Howard 2012. Intravesical gemcitabine therapy for non-muscle invasive bladder cancer (NMIBC): a systematic review. British Journal of Urology International 109 (4) , pp. 496-505. 10.1111/j.1464-410X.2011.10880.x |
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Jones, Gabriel, Cleves, Anne, Wilt, Timothy J., Mason, Malcolm David, Kynaston, Howard and Shelley, Mike 2012. Intravesical gemcitabine for non-muscle invasive bladder cancer. Cochrane Database of Systematic Reviews 1 , CD009294. 10.1002/14651858.CD009294.pub2 |
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Ablin, Richard J, Kynaston, Howard, Mason, Malcolm David and Jiang, Wen Guo 2011. Prostate transglutaminase (TGase-4) antagonizes the anti-tumour action of MDA-7/IL-24 in prostate cancer. Journal of Translational Medicine 9 , pp. 49-57. 10.1186/1479-5876-9-49 |
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Li, Jin, Ye, Lin, Kynaston, Howard and Jiang, Wen Guo 2011. Repulsive guidance molecules, novel bone morphogenetic protein co-receptors, are key regulators of the growth and aggressiveness of prostate cancer cells. International Journal of Oncology 40 (2) , pp. 544-550. 10.3892/ijo.2011.1251 |
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Shelley, Mike D., Mason, Malcolm David and Kynaston, Howard 2010. Intravesical therapy for superficial bladder cancer: a systematic review of randomised trials and meta-analyses. Cancer Treatment Reviews 36 (3) , pp. 195-205. 10.1016/j.ctrv.2009.12.005 |
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Zhang, Ning, Sanders, Andrew James, Ye, Lin, Kynaston, Howard and Jiang, Wen 2010. Expression of vascular endothelial growth inhibitor (VEGI) in human urothelial cancer of the bladder and its effects on the adhesion and migration of bladder cancer cells in vitro. Anticancer Research 30 (1) , pp. 87-95. |
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Jiang, Wen Guo, Ye, Lin, Ablin, Richard J., Kynaston, Howard and Mason, Malcolm David 2010. The prostate transglutaminase, TGase-4, coordinates with the HGFL/MSP-RON system in stimulating the migration of prostate cancer cells. International Journal of Oncology 37 (2) , pp. 413-418. 10.3892/ijo_00000689 |
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Bokobza, Sivan M., Ye, Lin, Kynaston, Howard and Jiang, Wen Guo 2010. Growth and differentiation factor-9 promotes adhesive and motile capacity of prostate cancer cells by up-regulating FAK and Paxillin via Smad dependent pathway. Oncology Reports 24 (6) , pp. 1653-1659. 10.3892/or_00001030 |
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Bokobza, Sivan Mili, Ye, Lin, Kynaston, Howard and Jiang, Wen Guo 2010. GDF-9 promotes the growth of prostate cancer cells by protecting them from apoptosis. Journal of Cellular Physiology 225 (2) , pp. 529-536. 10.1002/jcp.22235 |
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Bokobza, Sivan Mili, Ye, Lin, Kynaston, Howard and Jiang, Wen Guo 2010. Growth and differentiation factor 9 (GDF-9) induces epithelial-mesenchymal transition in prostate cancer cells. Molecular and Cellular Biochemistry 349 (1-2) , pp. 33-40. 10.1007/s11010-010-0657-5 |
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Fernando, Herman S., Sanders, Andrew James, Kynaston, Howard and Jiang, Wen Guo 2010. WAVE3 is associated with invasiveness in prostate cancer cells. Urologic Oncology: Seminars and Original Investigations 28 (3) , pp. 320-327. 10.1016/j.urolonc.2008.12.022 |
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Herman, Fernando, Martin, Tracey Amanda, Douglas-Jones, Anthony, Kynaston, Howard Gordon, Mansel, Robert Edward and Jiang, Wen Guo 2010. Expression of the ERM family members (ezrin, radixin and moesin) in breast cancer. Experimental and Therapeutic Medicine 1 (1) , pp. 153-160. 10.3892/etm_00000025 |
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Zhang, Ning, Sanders, Andrew James, Ye, Lin, Kynaston, Howard and Jiang, Wen Guo 2009. Vascular endothelial growth inhibitor, expression in human prostate cancer tissue and the impact on adhesion and migration of prostate cancer cells in vitro. International Journal of Oncology 35 (6) , pp. 1473-1480. 10.3892/ijo_00000466 |
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Ye, Lin, Kynaston, Howard and Jiang, Wen Guo 2009. Bone Morphogenetic Protein-10 suppresses the growth and aggressiveness of prostate cancer cells through a Smad independent pathway. The Journal of Urology 181 (6) , pp. 2749-2759. 10.1016/j.juro.2009.01.098 |
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Bokobza, Sivan Mili, Ye, Lin, Kynaston, Howard, Mansel, Robert Edward and Jiang, Wen Guo 2009. Reduced expression of BMPR-IB correlates with poor prognosis and increased proliferation of breast cancer cells. Cancer Genomics and Proteomics 6 (2) , pp. 101-108. |
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Fernando, Herman S., Kynaston, Howard and Jiang, Wen Guo 2009. WASP and WAVE proteins: vital intrinsic regulators of cell motility and their role in cancer (Review). International Journal of Molecular Medicine 23 (2) , pp. 141-148. 10.3892/ijmm_00000111 |
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Jiang, Wen Guo, Ablin, Richard J., Kynaston, Howard and Mason, Malcolm David 2009. The prostate transglutaminase (TGase-4, TGaseP) regulates the interaction of prostate cancer and vascular endothelial cells, a potential role for the ROCK pathway. Microvascular Research 77 (2) , pp. 150-157. 10.1016/j.mvr.2008.09.010 |
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van Andel, George, Bottomley, Andrew, Fosså, Sophie D., Efficace, Fabio, Coens, Corneel, Guerif, Stephane, Kynaston, Howard, Gontero, Paolo, Thalmann, George, Akdas, Atif, D?Haese, Sven and Aaronson, Neil K. 2008. An international field study of the EORTC QLQ-PR25: a questionnaire for assessing the health-related quality of life of patients with prostate cancer. European Journal of Cancer 44 (16) , pp. 2418-2424. 10.1016/j.ejca.2008.07.030 |
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Langley, Ruth E., Godsland, Ian F., Kynaston, Howard, Clarke, Noel W., Rosen, Stuart D., Morgan, Rachel C., Pollock, Philip, Kockelbergh, Roger, Lalani, El-Nasir, Dearnaley, David, Parmar, Mahesh and Abel, Paul D. 2008. Early hormonal data from a multicentre phase II trial using transdermal oestrogen patches as first-line hormonal therapy in patients with locally advanced or metastatic prostate cancer. BJU International 102 (4) , pp. 442-445. 10.1111/j.1464-410X.2008.07583.x |
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Hudson, E., Kynaston, Howard, Varma, Muralidharan, Carter, A., Staffurth, John Nicholas, Barber, Jim, Mason, Malcolm David and Lester, Jason Francis 2008. Radiotherapy after radical prostatectomy for adenocarcinoma of the prostate: a UK institutional experience and review of published studies. Clinical Oncology 20 (5) , pp. 353-357. 10.1016/j.clon.2008.02.008 |
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Fernando, Herman, Sanders, Andrew James, Jenkins, S., Kynaston, Howard and Jiang, Wen Guo 2008. Wave 3 (Wasp Verprolin-Homologous Protein) 3 is involved in the invasiveness of PC-3 cells [Abstract]. European Urology Supplements 7 (3) , p. 173. 10.1016/S1569-9056(08)60406-6 |
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Fernando, Herman S., Sanders, Andrew James, Kynaston, Howard and Jiang, Wen Guo 2008. WAVE1 is Associated with Invasiveness and Growth of Prostate Cancer Cells. The Journal of Urology 180 (4) , pp. 1515-1521. 10.1016/j.juro.2008.06.004 |
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Ye, Lin, Lewis-Russell, Jonathan M., Sanders, Andrew James, Kynaston, Howard Gordon and Jiang, Wen Guo 2008. HGF/SF up-regulates the expression of bone morphogenetic protein 7 in prostate cancer cells. Urologic Oncology: Seminars and Original Investigations 26 (2) , pp. 190-197. 10.1016/j.urolonc.2007.03.027 |
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Ye, Lin, Kynaston, Howard and Jiang, Wen Guo 2008. Bone morphogenetic protein-9 induces apoptosis in prostate cancer cells, the role of prostate apoptosis response-4. Molecular Cancer Research 6 (10) , pp. 1594-1606. 10.1158/1541-7786.MCR-08-0171 |
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Harland, S. J., Kynaston, Howard, Grigor, K., Wallace, D. M., Beacock, C., Kockelbergh, R., Clawson, S., Barlow, T., Parmar, M. K. and Griffiths, Gareth O. 2007. A randomized trial of radical radiotherapy for the management of pT1G3 NXM0 transitional cell carcinoma of the bladder. The Journal of Urology 178 (3 pt1) , pp. 807-813. The Journal of Urology |
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Bisson, Jonathan Ian, Chubb, H. L., Bennett, S., Mason, Malcolm David, Jones, D. and Kynaston, Howard Gordon 2002. The prevalence and predictors of psychological distress in patients with early localized prostate cancer. British Journal of Urology International 90 (1) , pp. 56-61. 10.1046/j.1464-410X.2002.02806.x |
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