Browse by All Cardiff Authors

Dev, Harveer, Linch, Mark, Narahari, Krishna ORCID: https://orcid.org/0000-0003-0257-7033, Milne-Clark, Toby, Cheung, Melissa, Warren, Anne, Malaviya, Alopa, Gnanapragasam, Vincent, Hernandez, Tatiana, Bullock, Nicholas, Machin, Andrea, Dayimu, Alimu, Robb, Tamsin, Cromwell, Elizabeth, Freeman, Alex, Harrington, Elizabeth A., Camacho, Niedzika, Glont, Silvia, Squatrito, Massimo, Rotem, Asaf, Moore, Luiza, Hanson, Robert, Dodd, Marc, Anand, Shubha, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Shaw, Greg, Shah, Nimish and Pacey, Simon 2025. Cambridge Neoadjuvant Cancer of the Prostate (CANCAP03): A window study into the effects of Olaparib ± Degarelix in primary prostate cancer. Clinical Cancer Research 31 (12) , pp. 2347-2357. 10.1158/1078-0432.ccr-24-1304

Parker, Chris C., Clarke, Noel W., Cook, Adrian D., Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 and Catton, Charles N. 2025. Adding 6 months of androgen deprivation therapy to postoperative radiotherapy for prostate cancer: a comparison of short-course versus no androgen deprivation therapy in the RADICALS-HD randomised controlled trial. The Lancet 403 (10442) , pp. 2405-2415. 10.1016/S0140-6736(24)00548-8

Parker, Chris C., Clarke, Noel W., Cook, Adrian D., Petersen, Peter M., Catton, Charles N., Cross, William R., Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Persad, Raj A., Saad, Fred, Logue, John, Payne, Heather, Amos, Claire, Bower, Lorna, Raman, Rakesh, Sayers, Ian, Worlding, Jane, Parulekar, Wendy R., Parmar, Mahesh K.B. and Sydes, Matthew R. 2024. Randomised trial of no, short-term, or long-term androgen deprivation therapy with postoperative radiotherapy after radical prostatectomy: results from the three-way comparison of RADICALS-HD (NCT00541047). European Urology 86 (5) , pp. 422-430. 10.1016/j.eururo.2024.07.026

Parker, C.C., Petersen, P.M., Cook, A.D., Clarke, N.W., Catton, C., Cross, W.R., Kynaston, H. ORCID: https://orcid.org/0000-0003-1902-9930, Parulekar, W.R., Persad, R.A., Saad, F., Bower, L., Durkan, G.C., Logue, J., Maniatis, C., Noor, D., Payne, H., Anderson, J., Bahl, A.K., Bashir, F., Bottomley, D.M., Brasso, K., Capaldi, L., Cooke, P.W., Chung, C., Donohue, J., Eddy, B., Heath, C.M., Henderson, A., Henry, A., Jaganathan, R., Jakobsen, H., James, N.D., Joseph, J., Lees, K., Lester, J., Lindberg, H., Makar, A., Morris, S.L., Oommen, N., Ostler, P., Owen, L., Patel, P., Pope, A., Popert, R., Raman, R., Ramani, V., Røder, A., Sayers, I., Simms, M., Srinivasan, V., Sundaram, S., Tarver, K.L., Tran, A., Wells, P., Wilson, J., Zarkar, A.M., Parmar, M.K.M. and Sydes, M.R. 2024. Timing of Radiotherapy (RT) after Radical Prostatectomy (RP): Long-term outcomes in the RADICALS-RT trial [NCT00541047]. Annals of Oncology 35 (7) , pp. 656-666. 10.1016/j.annonc.2024.03.010

Turnham, Daniel J. ORCID: https://orcid.org/0000-0002-2540-7363, Mullen, Manisha S., Bullock, Nicholas P., Gilroy, Kathryn L., Richards, Anna E., Patel, Radhika, Quintela, Marcos, Meniel, Valerie S., Seaton, Gillian, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Phesse, Toby J. ORCID: https://orcid.org/0000-0001-9568-4916, Nelson, Peter S., Haffner, Michael C., Staffurth, John N. ORCID: https://orcid.org/0000-0002-7834-3172 and Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843 2024. Development and characterisation of a new patient-derived Xenograft model of AR-negative metastatic asctration-resistant prostate cancer. Cells 13 (8) , 673. 10.3390/cells13080673

Joharatnam-Hogan, Nalinie, Hatem, Duaa, Cafferty, Fay H., Petrucci, Giovanna, Cameron, David A., Ring, Alistair, Kynaston, Howard G. ORCID: https://orcid.org/0000-0003-1902-9930, Gilbert, Duncan C., Wilson, Richard H., Hubner, Richard A., Swinson, Daniel E. B., Cleary, Siobhan, Robbins, Alex, MacKenzie, Mairead, Scott-Brown, Martin W. G., Sothi, Sharmila, Dawson, Lesley K., Capaldi, Lisa M., Churn, Mark, Cunningham, David, Khoo, Vincent, Armstrong, Anne C., Ainsworth, Nicola L., Horan, Gail, Wheatley, Duncan A., Mullen, Russell, Lofts, Fiona J., Walther, Axel, Herbertson, Rebecca A., Eaton, John D., O’Callaghan, Ann, Eichholz, Andrew, Kagzi, Mohammed M., Patterson, Daniel M., Narahari, Krishna, Bradbury, Jennifer, Stokes, Zuzana, Rizvi, Azhar J., Walker, Georgina A., Kunene, Victoria L., Srihari, Narayanan, Gentry-Maharaj, Aleksandra, Meade, Angela, Patrono, Carlo, Rocca, Bianca and Langley, Ruth E. 2023. Thromboxane biosynthesis in cancer patients and its inhibition by aspirin: a sub-study of the Add-Aspirin trial. British Journal of Cancer 129 (4) , pp. 706-720. 10.1038/s41416-023-02310-1

Hamdy, Freddie C., Donovan, Jenny L., Lane, J. Athene, Metcalfe, Chris, Davis, Michael, Turner, Emma L., Martin, Richard M., Young, Grace J., Walsh, Eleanor I., Bryant, Richard J., Bollina, Prasad, Doble, Andrew, Doherty, Alan, Gillatt, David, Gnanapragasam, Vincent, Hughes, Owen, Kockelbergh, Roger, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Paul, Alan, Paez, Edgar, Powell, Philip, Rosario, Derek J., Rowe, Edward, Mason, Malcolm ORCID: https://orcid.org/0000-0003-1505-2869, Catto, James W.F., Peters, Tim J., Oxley, Jon, Williams, Naomi J., Staffurth, John ORCID: https://orcid.org/0000-0002-7834-3172 and Neal, David E. 2023. Fifteen-year outcomes after monitoring, surgery, or radiotherapy for localized prostate cancer. New England Journal of Medicine 388 , pp. 1547-1558. 10.1056/NEJMoa2214122

Macnair, Archie, Nankivell, Matthew, Murray, Macey L., Rosen, Stuart D., Appleyard, Sally, Sydes, Matthew R., Forcat, Sylvia, Welland, Andrew, Clarke, Noel W., Mangar, Stephen, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Kockelbergh, Roger, Al-Hasso, Abdulla, Deighan, John, Marshall, John, Parmar, Mahesh, Langley, Ruth E. and Gilbert, Duncan C. 2023. Healthcare systems data in the context of clinical trials ? A comparison of cardiovascular data from a clinical trial dataset with routinely collected data. Contemporary Clinical Trials 128 , 107162. 10.1016/j.cct.2023.107162

Donovan, Jenny L., Hamdy, Freddie C., Lane, J. Athene, Young, Grace J., Metcalfe, Chris, Walsh, Eleanor I., Davis, Michael, Steuart-Feilding, Thomas, Blazeby, Jane M., Avery, Kerry N. L., Martin, Richard M., Bollina, Prasad, Doble, Andrew, Doherty, Alan, Gillatt, David, Gnanapragasam, Vincent, Hughes, Owen, Kockelbergh, Roger, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Paul, Alan, Paez, Edgar, Powell, Phillip, Rosario, Derek J., Rowe, Edward, Mason, Malcolm ORCID: https://orcid.org/0000-0003-1505-2869, Catto, James W. F., Peters, Tim J., Wade, Julia, Turner, Emma L., Williams, Naomi J., Oxley, Jon, Staffurth, John ORCID: https://orcid.org/0000-0002-7834-3172, Bryant, Richard J. and Neal, David E. 2023. Patient-reported outcomes 12 years after localized prostate cancer treatment. NEJM Evidence 2 , 4. 10.1056/EVIDoa2300018

Minto, T., Abdelrahman, T., Jones, L., Wheat, J., Key, T., Shivakumar, N., Ansell, J., Seddon, O., Cronin, A., Tomkinson, A., Theron, A., Trickett, R.W., Sagua, N., Sultana, S., Clark, A., McKay, E., Johnson, A., Behera, Karishma, Towler, J., Kynaston, H. ORCID: https://orcid.org/0000-0003-1902-9930, Mohamed, A, Blackshaw, G.., Thomas, R, Jones, S., Shinkwin, M., Perry, H., Edgbeare, D., Chopra, S., DaSilva, L., Williams, I., Contractor, U., Bell, S., Zaher, S., Stechman, M., Berry, S., Clark, H., Bois, E., Von Oppell, C., Ackerman, L., Ablorsu, E., Horwood, J., Mehta, D., Featherstone, J., Folaranmi, E., Bray, M., Siddall, K., King, E., Phillips, M., Morgan, J., Chopra, I., Evans, D., Whitehouse, K., Leach, P., Thomas, C., Davies, E., Dyer, M., Fox, A., Ireland, E., Meehan, E., Mukit, A., Newell, K., Parry, D., Popham, B., Chapman, C. and Botros, H. 2022. Safety of maintaining elective and emergency surgery during the COVID-19 pandemic with the introduction of a Protected Elective Surgical Unit (PESU): A cross-specialty evaluation of 30-day outcomes in 9,925 patients undergoing surgery in a University Health Board. Surgery Open Science 10 , pp. 168-173. 10.1016/j.sopen.2022.09.005

Shephard, Alex P., Giles, Peter ORCID: https://orcid.org/0000-0003-3143-6854, Mbengue, Mariama, Alraies, Amr, Spary, Lisa K., Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Gurney, Mark J. ORCID: https://orcid.org/0000-0003-1119-6638, Falcón-Pérez, Juan M., Royo, Félix, Tabi, Zsuzsanna, Parthimos, Dimitris, Errington, Rachel J., Clayton, Aled and Webber, Jason P. 2021. Stroma-derived extracellular vesicle mRNA signatures inform histological nature of prostate cancer. Journal of Extracellular Vesicles 10 (12) , e12150. 10.1002/jev2.12150

Tan, Wei Shen, Arianayagam, Rajan, Khetrapal, Pramit, Rowe, Edward, Kearley, Samantha, Mahrous, Ahmed, Pal, Raj, Fowler, William, Heer, Rakesh, Elajnaf, Mohamed, Douglas-Moore, Jayne, Leyshon Griffiths, T.R., Voss, James, Wilby, Daniel, Al Kadhi, Omar, Noel, Jonathan, Vasdev, Nikhil, McKay, Alastair, Ahmad, Imran, Abu-Nayla, Islam, Lamb, Benjamin, Hill, George T., Narahari, Krishna ORCID: https://orcid.org/0000-0003-0257-7033, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Yousuf, Arzu, Kusuma, Venkata R.M., Cresswell, Jo, Cooke, Pete, Chakravarti, Aniruddha, Barod, Ravi, Bex, Axel and Kelly, John D. 2021. Major urological cancer surgery for patients is safe and surgical training should be encouraged during the covid-19 pandemic: a multicentre analysis of 30-day outcomes. European Urology Open Science 25 , pp. 39-43. 10.1016/j.euros.2021.01.005

Langley, Ruth E., Gilbert, Duncan C., Duong, Trinh, Clarke, Noel W., Nankivell, Matthew, Rosen, Stuart D., Mangar, Stephen, Macnair, Archie, Sundaram, Subramanian Kanaga, Laniado, Marc E., Dixit, Sanjay, Madaan, Sanjeev, Manetta, Caroline, Pope, Alvan, Scrase, Christopher D., Mckay, Stephen, Muazzam, Iqtedar A., Collins, Gerald N., Worlding, Jane, Williams, Simon T., Paez, Edgar, Robinson, Angus, McFarlane, Jonathan, Deighan, John V., Marshall, John, Forcat, Silvia, Weiss, Melanie, Kockelbergh, Roger, Alhasso, Abdulla, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 and Parmar, Mahesh 2021. Transdermal oestradiol for androgen suppression in prostate cancer: long-term cardiovascular outcomes from the randomised Prostate Adenocarcinoma Transcutaneous Hormone (PATCH) trial programme. Lancet 397 (10274) , pp. 581-591. 10.1016/S0140-6736(21)00100-8

Bullock, Nicholas, Simpkin, Andrew, Fowler, Sarah, Varma, Murali, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 and Narahari, Krishna 2019. Pathological upgrading in prostate cancer treated with surgery in the United Kingdom: trends and risk factors from the British Association of Urological Surgeons Radical Prostatectomy Registry. BMC Urology 19 (1) , -. 10.1186/s12894-019-0526-9

Bullock, Nicholas, Serag, Hosam and Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 2019. Radical open surgery for management of extensive extra-prostatic benign prostatic hyperplasia. Journal of Clinical Urology 12 (5) , pp. 398-400. 10.1177/2051415818767181

Burnell, Stephanie E. A., Spencer-Harty, Samantha, Howarth, Suzie, Bodger, Owen, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Morgan, Claire and Doak, Shareen H. 2019. Utilisation of the STEAP protein family in a diagnostic setting may provide a more comprehensive prognosis of prostate cancer. PLoS ONE 14 (8) , e0220456. 10.1371/journal.pone.0220456

Foley, Kieran, Christian, Adam, Peaker, J., Marshall, Christopher ORCID: https://orcid.org/0000-0002-2228-883X, Spezi, Emiliano ORCID: https://orcid.org/0000-0002-1452-8813, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 and Roberts, Stuart A. 2019. Cyclo-oxygenase-2 expression is associated with mean standardised uptake value on 18F-fluorodeoxyglucose positron emission tomography in oesophageal adenocarcinoma. British Journal of Radiology 92 (1099) , 20180668. 10.1259/bjr.20180668

Pacey, Simon, Linch, Mark David, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Warren, Anne, Freeman, Alex, Tysoe, Ruth, Shaw, Greg, Narahari, Krishna ORCID: https://orcid.org/0000-0003-0257-7033, Kumar, Satish, Martin, Henno, Kularatne, Bihani, Gnanapragasam, Vincent, Davies, Barry, Khan, Josephine, Bratt, Ola, Dev, Harveer, Massie, Charles and Shah, Nimish 2019. A study into the pharmacodynamic biomarker effects of olaparib (PARP Inhibitor) ± degarelix (GnRH antagonist) given prior to radical prostatectomy (RP) CANCAP03. Journal of Clinical Oncology 37 (7_supp) 10.1200/JCO.2019.37.7_suppl.35

Varma, Murali, Cochlin, Dennis, Delahunt, Brett, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Rees, John, Rous, Brian and Narahari, Krishna ORCID: https://orcid.org/0000-0003-0257-7033 2018. TNM clinical staging of prostate cancer: issues and solutions. BJU International 123 (3) , pp. 382-384. 10.1111/bju.14589

Burnell, Stephanie E. A., Spencer-Harty, Samantha, Howarth, Suzie, Bodger, Owen, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Morgan, Claire and Doak, Shareen H. 2018. STEAP2 knockdown reduces the invasive potential of prostate cancer cells. Scientific Reports 8 (1) , 6252. 10.1038/s41598-018-24655-x

Donovan, Jenny L., Young, Grace J., Walsh, Eleanor I., Metcalfe, Chris, Lane, J. Athene, Martin, Richard M., Tazewell, Marta K., Davis, Michael, Peters, Tim J., Turner, Emma L., Mills, Nicola, Khazragui, Hanan, Khera, Tarnjit K., Neal, David E., Hamdy, Freddie C., Bollina, Prasad, Catto, James, Doble, Andrew, Doherty, Alan, Gillatt, David, Gnanapragasam, Vincent, Holding, Peter, Hughes, Owen, Kockelbergh, Roger, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Mason, Malcolm ORCID: https://orcid.org/0000-0003-1505-2869, Oxley, Jon, Paul, Alan, Paez, Edgar, Rosario, Derek J., Rowe, Edward and Staffurth, John ORCID: https://orcid.org/0000-0002-7834-3172 2018. A prospective cohort and extended comprehensive-cohort design provided insights about the generalizability of a pragmatic trial: the ProtecT prostate cancer trial. Journal of Clinical Epidemiology 96 , pp. 35-46. 10.1016/j.jclinepi.2017.12.019

Jefferies, Matthew T., Cox, Adam C., Shorning, Boris Y., Meniel, Valerie, Griffiths, David, Kynaston, Howard G. ORCID: https://orcid.org/0000-0003-1902-9930, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 and Clarke, Alan R. 2017. PTEN loss and activation of K-RAS and β-catenin cooperate to accelerate prostate tumourigenesis. Journal of Pathology 243 (4) , pp. 442-456. 10.1002/path.4977

KandaSwamy, Gokul V., Bennett, Adam, Narahari, Krishna ORCID: https://orcid.org/0000-0003-0257-7033, Hughes, Owen, Rees, John and Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 2017. Establishing the pathways and indications for performing isotope bone scans in newly diagnosed intermediate-risk localised prostate cancer – results from a large contemporaneous cohort. BJU International 120 (5B) , E59-E63. 10.1111/bju.13850

Jefferies, Matthew T., Pope, Christopher, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Clarke, Alan R., Martin, Richard and Adams, Josephine 2017. Analysis of fascin-1 in relation to gleason risk classification and nuclear ets-related gene status of human prostate carcinomas: an immunohistochemical study of clinically annotated tumours from the Wales Cancer Bank. Biomarkers in Cancer 9 , pp. 1-8. 10.1177/1179299X17710944

Gilbert, Duncan C., Duong, Trinh, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Alhasso, Abdulla A., Cafferty, Fay H., Rosen, Stuart D., Kanaga-Sundaram, Subramanian, Dixit, Sanjay, Laniado, Marc, Madaan, Sanjeev, Collins, Gerald, Pope, Alvan, Welland, Andrew, Nankivell, Matthew, Wassersug, Richard, Parmar, Mahesh K. B., Langley, Ruth E. and Abel, Paul D. 2016. Quality-of-life outcomes from the Prostate Adenocarcinoma: TransCutaneous Hormones (PATCH) trial evaluating luteinising hormone-releasing hormone agonists versus transdermal oestradiol for androgen suppression in advanced prostate cancer. BJU International 119 (5) , pp. 667-675. 10.1111/bju.13687

Coyle, Christopher, Cafferty, Fay H., Rowley, Samuel, MacKenzie, Mairead, Berkman, Lindy, Gupta, Sudeep, Pramesh, C S, Gilbert, Duncan, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Cameron, David, Wilson, Richard H., Ring, Alistair and Langley, Ruth E. 2016. ADD-ASPIRIN: A phase III, double-blind, placebo controlled, randomised trial assessing the effects of aspirin on disease recurrence and survival after primary therapy in common non-metastatic solid tumours. Contemporary Clinical Trials 51 , pp. 56-64. 10.1016/j.cct.2016.10.004

Hamdy, Freddie, Donovan, Jenny, Lane, J. Athene, Mason, Malcolm ORCID: https://orcid.org/0000-0003-1505-2869, Metcalfe, Chris, Holding, Peter, Davis, Michael, Peters, Tim J., Turner, Emma L., Martin, Richard M., Oxley, Jon, Robinson, Mary, Staffurth, John, Walsh, Eleanor, Bollina, Prasad, Catto, James, Doble, Andrew, Doherty, Alan, Gillatt, David, Kockelbergh, Roger, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Paul, Alan, Powell, Philip, Prescott, Stephen, Rosario, Derek J., Rowe, Edward and Neal, David E. 2016. 10-Year outcomes after monitoring, surgery, or radiotherapy for localized prostate cancer. New England Journal of Medicine 375 , pp. 1415-1424. 10.1056/NEJMoa1606220

Donovan, Jenny L., Hamdy, Freddie C., Lane, J. Athene, Mason, Malcolm ORCID: https://orcid.org/0000-0003-1505-2869, Metcalfe, Chris, Walsh, Eleanor, Blazeby, Jane M., Peters, Tim J., Holding, Peter, Bonnington, Susan, Lennon, Teresa, Bradshaw, Lynne, Cooper, Deborah, Herbert, Phillipa, Howson, Joanne, Jones, Amanda, Lyons, Norma, Salter, Elizabeth, Thompson, Pauline, Tidball, Sarah, Blaikie, Jan, Gray, Catherine, Bollina, Prasad, Catto, James, Doble, Andrew, Doherty, Alan, Gillatt, David, Kockelbergh, Roger, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Paul, Alan, Powell, Philip, Prescott, Stephen, Rosario, Derek J., Rowe, Edward, Davis, Michael, Turner, Emma L., Martin, Richard M. and Neal, David E. 2016. Patient-reported outcomes after monitoring, surgery, or radiotherapy for prostate cancer. New England Journal of Medicine 375 , pp. 1425-1437. 10.1056/NEJMoa1606221

Langley, Ruth E., Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Alhasso, Abdulla A., Duong, Trinh, Paez, Edgar M., Jovic, Gordana, Scrase, Christopher D., Robertson, Andrew, Cafferty, Fay, Welland, Andrew, Carpenter, Robin, Honeyfield, Lesley, Abel, Richard L., Stone, Michael D., Parmar, Mahesh K.B. and Abel, Paul D. 2016. A randomised comparison evaluating changes in bone mineral density in advanced prostate cancer: luteinising hormone-releasing hormone agonists versus transdermal oestradiol. European Urology 69 (6) , pp. 1016-1025. 10.1016/j.eururo.2015.11.030

Weeks, Hoi, Sanders, Andrew ORCID: https://orcid.org/0000-0002-7997-5286, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 and Jiang, Wen ORCID: https://orcid.org/0000-0002-3283-1111 2016. The association between WAVE1 and -3 and the ARP2/3 complex in PC 3 cells. Anticancer Research 36 (3) , pp. 1135-1142.

Moazzam, Muhammad, Ye, Lin ORCID: https://orcid.org/0000-0002-0303-2409, Sun, Ping-Hui, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2015. Knockdown of WAVE3 impairs HGF induced migration and invasion of prostate cancer cells. Cancer Cell International 15 , 51. 10.1186/s12935-015-0203-3

Webber, J. P. ORCID: https://orcid.org/0000-0003-4772-3014, Spary, L. K., Sanders, A. J. ORCID: https://orcid.org/0000-0002-7997-5286, Chowdhury, R., Jiang, W. G. ORCID: https://orcid.org/0000-0002-3283-1111, Steadman, R. ORCID: https://orcid.org/0000-0002-1303-2496, Wymant, J., Jones, A. T. ORCID: https://orcid.org/0000-0003-2781-8905, Kynaston, H. ORCID: https://orcid.org/0000-0003-1902-9930, Mason, M. D. ORCID: https://orcid.org/0000-0003-1505-2869, Tabi, Z. and Clayton, A. ORCID: https://orcid.org/0000-0002-3087-9226 2015. Differentiation of tumour-promoting stromal myofibroblasts by cancer exosomes. Oncogene 34 (3) , pp. 290-302. 10.1038/onc.2013.560

Whiteland, Helen, Spencer-Harty, Samantha, Morgan, Claire, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Thomas, David Hywel, Bose, Pradeep, Fenn, Neil, Lewis, Paul, Jenkins, Spencer and Doak, Shareen H. 2014. A role for STEAP2 in prostate cancer progression. Clinical & Experimental Metastasis 31 (8) , pp. 909-920. 10.1007/s10585-014-9679-9

Aboumarzouk, O.M., Zreik, A., Hughes, O., Narahari, K. ORCID: https://orcid.org/0000-0003-0257-7033, Coulthard, R., Kynaston, H. ORCID: https://orcid.org/0000-0003-1902-9930, Chlosta, P. and Somani, B.K. 2014. 670 Emphysematous pyelonephritis: time for a management plan with an evidence based approach. European Urology Supplements 13 (1) , e670. 10.1016/S1569-9056(14)60660-6

Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111, Ye, Lin ORCID: https://orcid.org/0000-0002-0303-2409, Sanders, Andrew James ORCID: https://orcid.org/0000-0002-7997-5286, Ruge, Fiona, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Ablin, Richard J. and Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869 2013. Prostate transglutaminase (TGase-4, TGaseP) enhances the adhesion of prostate cancer cells to extracellular matrix, the potential role of TGase-core domain. Journal of Translational Medicine 11 , 269. 10.1186/1479-5876-11-269

Aboumarzouk, Omar, Hughes, Owen, Narahari, Krishna, Drewa, Tomasz, Chlosta, Piotr L. and Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 2013. Safety and feasibility of Laparoscopic Radical Cystectomy for the treatment of bladder cancer. Journal of Endourology 27 (9) , pp. 1083-1095. 10.1089/end.2013.0084

Langley, Ruth E., Cafferty, Fay H., Alhasso, Abdulla A., Rosen, Stuart D., Sundaram, Subramanian Kanaga, Freeman, Suzanne C., Pollock, Philip, Jinks, Rachel C., Godsland, Ian F., Kockelbergh, Roger, Clarke, Noel W., Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Parmar, Mahesh K. B. and Abel, Paul D. 2013. Cardiovascular outcomes in patients with locally advanced and metastatic prostate cancer treated with luteinising-hormone-releasing-hormone agonists or transdermal oestrogen: the randomised, phase 2 MRC PATCH trial (PR09). The Lancet Oncology 14 (4) , pp. 306-316. 10.1016/S1470-2045(13)70025-1

Williams, Rebecca ORCID: https://orcid.org/0000-0003-2168-7369, Shorning, Boris, Datta, S., Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 and Clarke, Alan Richard ORCID: https://orcid.org/0000-0002-4281-426X 2012. Development and characterisation of a bladder cancer model [Poster]. BJU International 109 (S7) , p. 25. 10.1111/j.1464-410X.2012.11177.x

Shelley, Mike D., Jones, Gabriel, Cleves, Anne, Wilt, Timothy J., Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869 and Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 2012. Intravesical gemcitabine therapy for non-muscle invasive bladder cancer (NMIBC): a systematic review. British Journal of Urology International 109 (4) , pp. 496-505. 10.1111/j.1464-410X.2011.10880.x

Jones, Gabriel, Cleves, Anne ORCID: https://orcid.org/0000-0002-9899-7894, Wilt, Timothy J., Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 and Shelley, Mike 2012. Intravesical gemcitabine for non-muscle invasive bladder cancer. Cochrane Database of Systematic Reviews 1 , CD009294. 10.1002/14651858.CD009294.pub2

Ablin, Richard J, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869 and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2011. Prostate transglutaminase (TGase-4) antagonizes the anti-tumour action of MDA-7/IL-24 in prostate cancer. Journal of Translational Medicine 9 , pp. 49-57. 10.1186/1479-5876-9-49

Li, Jin, Ye, Lin ORCID: https://orcid.org/0000-0002-0303-2409, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2011. Repulsive guidance molecules, novel bone morphogenetic protein co-receptors, are key regulators of the growth and aggressiveness of prostate cancer cells. International Journal of Oncology 40 (2) , pp. 544-550. 10.3892/ijo.2011.1251

Shelley, Mike D., Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869 and Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 2010. Intravesical therapy for superficial bladder cancer: a systematic review of randomised trials and meta-analyses. Cancer Treatment Reviews 36 (3) , pp. 195-205. 10.1016/j.ctrv.2009.12.005

Zhang, Ning, Sanders, Andrew James ORCID: https://orcid.org/0000-0002-7997-5286, Ye, Lin ORCID: https://orcid.org/0000-0002-0303-2409, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 and Jiang, Wen ORCID: https://orcid.org/0000-0002-3283-1111 2010. Expression of vascular endothelial growth inhibitor (VEGI) in human urothelial cancer of the bladder and its effects on the adhesion and migration of bladder cancer cells in vitro. Anticancer Research 30 (1) , pp. 87-95.

Bokobza, Sivan Mili, Ye, Lin ORCID: https://orcid.org/0000-0002-0303-2409, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2010. Growth and differentiation factor 9 (GDF-9) induces epithelial-mesenchymal transition in prostate cancer cells. Molecular and Cellular Biochemistry 349 (1-2) , pp. 33-40. 10.1007/s11010-010-0657-5

Bokobza, Sivan Mili, Ye, Lin ORCID: https://orcid.org/0000-0002-0303-2409, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2010. GDF-9 promotes the growth of prostate cancer cells by protecting them from apoptosis. Journal of Cellular Physiology 225 (2) , pp. 529-536. 10.1002/jcp.22235

Bokobza, Sivan M., Ye, Lin ORCID: https://orcid.org/0000-0002-0303-2409, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2010. Growth and differentiation factor-9 promotes adhesive and motile capacity of prostate cancer cells by up-regulating FAK and Paxillin via Smad dependent pathway. Oncology Reports 24 (6) , pp. 1653-1659. 10.3892/or_00001030

Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111, Ye, Lin ORCID: https://orcid.org/0000-0002-0303-2409, Ablin, Richard J., Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 and Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869 2010. The prostate transglutaminase, TGase-4, coordinates with the HGFL/MSP-RON system in stimulating the migration of prostate cancer cells. International Journal of Oncology 37 (2) , pp. 413-418. 10.3892/ijo_00000689

Herman, Fernando, Martin, Tracey Amanda ORCID: https://orcid.org/0000-0003-2690-4908, Douglas-Jones, Anthony, Kynaston, Howard Gordon ORCID: https://orcid.org/0000-0003-1902-9930, Mansel, Robert Edward ORCID: https://orcid.org/0000-0002-8051-0726 and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2010. Expression of the ERM family members (ezrin, radixin and moesin) in breast cancer. Experimental and Therapeutic Medicine 1 (1) , pp. 153-160. 10.3892/etm_00000025

Fernando, Herman S., Sanders, Andrew James ORCID: https://orcid.org/0000-0002-7997-5286, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2010. WAVE3 is associated with invasiveness in prostate cancer cells. Urologic Oncology: Seminars and Original Investigations 28 (3) , pp. 320-327. 10.1016/j.urolonc.2008.12.022

Zhang, Ning, Sanders, Andrew James ORCID: https://orcid.org/0000-0002-7997-5286, Ye, Lin ORCID: https://orcid.org/0000-0002-0303-2409, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2009. Vascular endothelial growth inhibitor, expression in human prostate cancer tissue and the impact on adhesion and migration of prostate cancer cells in vitro. International Journal of Oncology 35 (6) , pp. 1473-1480. 10.3892/ijo_00000466

Ye, Lin ORCID: https://orcid.org/0000-0002-0303-2409, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2009. Bone Morphogenetic Protein-10 suppresses the growth and aggressiveness of prostate cancer cells through a Smad independent pathway. The Journal of Urology 181 (6) , pp. 2749-2759. 10.1016/j.juro.2009.01.098

Bokobza, Sivan Mili, Ye, Lin ORCID: https://orcid.org/0000-0002-0303-2409, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Mansel, Robert Edward ORCID: https://orcid.org/0000-0002-8051-0726 and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2009. Reduced expression of BMPR-IB correlates with poor prognosis and increased proliferation of breast cancer cells. Cancer Genomics and Proteomics 6 (2) , pp. 101-108.

Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111, Ablin, Richard J., Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 and Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869 2009. The prostate transglutaminase (TGase-4, TGaseP) regulates the interaction of prostate cancer and vascular endothelial cells, a potential role for the ROCK pathway. Microvascular Research 77 (2) , pp. 150-157. 10.1016/j.mvr.2008.09.010

Fernando, Herman S., Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2009. WASP and WAVE proteins: vital intrinsic regulators of cell motility and their role in cancer (Review). International Journal of Molecular Medicine 23 (2) , pp. 141-148. 10.3892/ijmm_00000111

van Andel, George, Bottomley, Andrew, Fosså, Sophie D., Efficace, Fabio, Coens, Corneel, Guerif, Stephane, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Gontero, Paolo, Thalmann, George, Akdas, Atif, D?Haese, Sven and Aaronson, Neil K. 2008. An international field study of the EORTC QLQ-PR25: a questionnaire for assessing the health-related quality of life of patients with prostate cancer. European Journal of Cancer 44 (16) , pp. 2418-2424. 10.1016/j.ejca.2008.07.030

Langley, Ruth E., Godsland, Ian F., Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Clarke, Noel W., Rosen, Stuart D., Morgan, Rachel C., Pollock, Philip, Kockelbergh, Roger, Lalani, El-Nasir, Dearnaley, David, Parmar, Mahesh and Abel, Paul D. 2008. Early hormonal data from a multicentre phase II trial using transdermal oestrogen patches as first-line hormonal therapy in patients with locally advanced or metastatic prostate cancer. BJU International 102 (4) , pp. 442-445. 10.1111/j.1464-410X.2008.07583.x

Hudson, E., Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Varma, Muralidharan, Carter, A., Staffurth, John Nicholas ORCID: https://orcid.org/0000-0002-7834-3172, Barber, Jim, Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869 and Lester, Jason Francis 2008. Radiotherapy after radical prostatectomy for adenocarcinoma of the prostate: a UK institutional experience and review of published studies. Clinical Oncology 20 (5) , pp. 353-357. 10.1016/j.clon.2008.02.008

Ye, Lin ORCID: https://orcid.org/0000-0002-0303-2409, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2008. Bone morphogenetic protein-9 induces apoptosis in prostate cancer cells, the role of prostate apoptosis response-4. Molecular Cancer Research 6 (10) , pp. 1594-1606. 10.1158/1541-7786.MCR-08-0171

Fernando, Herman S., Sanders, Andrew James ORCID: https://orcid.org/0000-0002-7997-5286, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2008. WAVE1 is Associated with Invasiveness and Growth of Prostate Cancer Cells. The Journal of Urology 180 (4) , pp. 1515-1521. 10.1016/j.juro.2008.06.004

Ye, Lin ORCID: https://orcid.org/0000-0002-0303-2409, Lewis-Russell, Jonathan M., Sanders, Andrew James ORCID: https://orcid.org/0000-0002-7997-5286, Kynaston, Howard Gordon ORCID: https://orcid.org/0000-0003-1902-9930 and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2008. HGF/SF up-regulates the expression of bone morphogenetic protein 7 in prostate cancer cells. Urologic Oncology: Seminars and Original Investigations 26 (2) , pp. 190-197. 10.1016/j.urolonc.2007.03.027

Fernando, Herman, Sanders, Andrew James ORCID: https://orcid.org/0000-0002-7997-5286, Jenkins, S., Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930 and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2008. Wave 3 (Wasp Verprolin-Homologous Protein) 3 is involved in the invasiveness of PC-3 cells [Abstract]. European Urology Supplements 7 (3) , p. 173. 10.1016/S1569-9056(08)60406-6

Harland, S. J., Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Grigor, K., Wallace, D. M., Beacock, C., Kockelbergh, R., Clawson, S., Barlow, T., Parmar, M. K. and Griffiths, Gareth O. 2007. A randomized trial of radical radiotherapy for the management of pT1G3 NXM0 transitional cell carcinoma of the bladder. The Journal of Urology 178 (3 pt1) , pp. 807-813. The Journal of Urology

Bisson, Jonathan Ian ORCID: https://orcid.org/0000-0001-5170-1243, Chubb, H. L., Bennett, S., Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869, Jones, D. and Kynaston, Howard Gordon ORCID: https://orcid.org/0000-0003-1902-9930 2002. The prevalence and predictors of psychological distress in patients with early localized prostate cancer. British Journal of Urology International 90 (1) , pp. 56-61. 10.1046/j.1464-410X.2002.02806.x