Krishnacoumar, Brenda, Stenzel, Martin, Garibagaoglu, Hilal, Omata, Yasunori, Sworn, Rachel L., Hofmann, Thea, Ipseiz, Natacha, Czubala, Magdalena A. ORCID: https://orcid.org/0000-0001-9881-1095, Steffen, Ulrike, Maccataio, Antonio, Stoll, Cornelia, Böhm, Christina, Herrmann, Martin, Uderhardt, Stefan, Jenkins, Robert H. ORCID: https://orcid.org/0000-0001-8500-9044, Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421, Grüneboom, Anika, Zaiss, Mario M., Schett, Georg, Krönke, Gerhard and Scholtysek, Carina
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Tissue-specific transcriptional programming of macrophages controls the microRNA transcriptome targeting multiple functional pathways.
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Gurney, Mark ORCID: https://orcid.org/0000-0003-1119-6638, Davies, Luke C., Jones, Ruth E., Bart, Valentina M., Jenkins, Robert H. ORCID: https://orcid.org/0000-0001-8500-9044, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421 and Czubala, Magdalena A. ORCID: https://orcid.org/0000-0001-9881-1095
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Lentiviral vector preparation for efficient gene and microRNA modulation of peritoneal cavity tissue-resident macrophages in vivo in mice.
Journal of Visualized Experiments
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Millrine, David ORCID: https://orcid.org/0000-0002-8041-0151, Jenkins, Robert H ORCID: https://orcid.org/0000-0001-8500-9044, Hughes, Stuart T O and Jones, Simon A ORCID: https://orcid.org/0000-0001-7297-9711
2022.
Making sense of IL-6 signalling cues in pathophysiology.
FEBS Letters
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10.1002/1873-3468.14201
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Newbury, Lucy J., Simpson, Kate, Khalid, Usman, John, Imogen, de Rivera, Lluís Bailach, Lu, Yueh-An, Lopez-Anton, Melisa, Watkins, William J. ORCID: https://orcid.org/0000-0003-3262-6588, Jenkins, Robert H. ORCID: https://orcid.org/0000-0001-8500-9044, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435
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miR-141 mediates recovery from acute kidney injury.
Scientific Reports
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Midgley, Adam C., Woods, Emma, Jenkins, Robert ORCID: https://orcid.org/0000-0001-8500-9044, Brown, Charlotte, Khalid, Usman, Chavez, Rafael, Hascall, Vincent, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496, Phillips, Aled O. ORCID: https://orcid.org/0000-0001-9744-7113 and Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978
2020.
Hyaluronidase-2 regulates RhoA signalling, myofibroblast contractility and other key pro-fibrotic myofibroblast functions.
American Journal of Pathology
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Ipseiz, Natacha ORCID: https://orcid.org/0000-0001-5008-8889, Czubala, Magdalena A. ORCID: https://orcid.org/0000-0001-9881-1095, Bart, Valentina M.T., Davies, Luke C., Jenkins, Robert H. ORCID: https://orcid.org/0000-0001-8500-9044, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 and Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421
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Effective in vivo gene modification in mouse tissue-resident peritoneal macrophages by intraperitoneal delivery of lentiviral vectors.
Molecular Therapy - Methods and Clinical Development
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10.1016/j.omtm.2019.10.004
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Khalid, Usman, Newbury, Lucy J., Simpson, Kate, Jenkins, Robert H. ORCID: https://orcid.org/0000-0001-8500-9044, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Bates, Lucy, Sheerin, Neil S., Chavez, Rafael and Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342
2019.
A urinary microRNA panel that is an early predictive biomarker of delayed graft function following kidney transplant.
Scientific Reports
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Beltrami, Cristina, Simpson, Kate, Jesky, Mark, Wonnacott, Alexa ORCID: https://orcid.org/0000-0002-0968-4248, Carrington, Christopher, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, Newbury, Lucy, Jenkins, Robert ORCID: https://orcid.org/0000-0001-8500-9044, Ashdown, Thomas, Dayan, Colin ORCID: https://orcid.org/0000-0002-6557-3462, Satchell, Simon, Corish, Peter, Cockwell, Paul, Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435
2018.
Association of elevated urinary miR-126, miR-155, and miR-29b with diabetic kidney disease.
American Journal of Pathology
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10.1016/j.ajpath.2018.06.006
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Lopez-Anton, Melisa, Lambie, Mark, Lopez-Cabrera, Manuel, Schmitt, Claus P., Ruiz-Carpio, Vicente, Bartosova, Maria, Schaefer, Betti, Davies, Simon, Stone, Timothy ORCID: https://orcid.org/0000-0003-4591-9611, Jenkins, Robert ORCID: https://orcid.org/0000-0001-8500-9044, Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421, Topley, Nicholas, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342
2017.
miR-21 promotes fibrogenesis in peritoneal dialysis.
American Journal of Pathology
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10.1016/j.ajpath.2017.03.007
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Khalid, Usman, Ablorsu, Elijah, Szabo, Laszlo, Jenkins, Robert H. ORCID: https://orcid.org/0000-0001-8500-9044, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Chavez, Rafael and Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342
2016.
MicroRNA-21 (miR-21) expression in hypothermic machine perfusate may be predictive of early outcomes in kidney transplantation.
Clinical Transplantation
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10.1111/ctr.12679
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Chavez, Rafael, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Nesargikar, Prabhu, Pino-Chavez, Gilda and Khalid, Usman
2016.
Kidney ischaemia reperfusion injury in the rat: the EGTI scoring system as a valid and reliable tool for histological assessment.
Journal of Histology and Histopathology
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Nesargikar, Prabhu, Spiller, Brad, Jenkins, Robert ORCID: https://orcid.org/0000-0001-8500-9044, Khalid, Usman, Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 and Chavez, Rafael
2015.
Modulation of leukocytes and endothelium by anti-thymocyte globulin confers protection against renal ischemia reperfusion injury in rats.
Transplant International
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Nesargikar, Prabhu, Pino-Chavez, Gilda, Spiller, Owen Bradley ORCID: https://orcid.org/0000-0002-9117-6911, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044 and Chavez, Rafael
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Single dose sCR1 attenuates renal ischemia reperfusion injury in rats despite early reconstitution of the complement system [Abstract].
Transplant International
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Khalid, Usman, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Simpson, Katherine, Ablorsu, Elijah, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Chavez, Rafael
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Urinary microrna expression predicts delayed graft function in kidney transplantation [Abstract].
Transplant International
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Beltrami, Cristina, Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226, Newbury, Lucy, Corish, Peter, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435
2015.
Stabilization of urinary microRNAs by association with exosomes and argonaute 2 protein.
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Midgley, Adam C., Druggal, Lucy, Jenkins, Robert ORCID: https://orcid.org/0000-0001-8500-9044, Hascall, Vincent, Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496, Phillips, Aled O. ORCID: https://orcid.org/0000-0001-9744-7113 and Meran, Soma ORCID: https://orcid.org/0000-0003-3408-3978
2015.
Hyaluronan regulates bone morphogenetic protein-7-dependent prevention and reversal of myofibroblast phenotype.
Journal of Biological Chemistry
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10.1074/jbc.M114.625939
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Jenkins, Robert ORCID: https://orcid.org/0000-0001-8500-9044, Liao, Chia-Te, Wallace, Leah, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Topley, Nicholas, Taylor, Philip ORCID: https://orcid.org/0000-0003-0163-1421 and Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342
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Microrna regulation of macrophage phenotype in peritoneal fibrosis.
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Khalid, Usman, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Fraser, Donald ORCID: https://orcid.org/0000-0003-0102-9342 and Jenkins, Robert ORCID: https://orcid.org/0000-0001-8500-9044
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Acute kidney injury: a paradigm for miRNA regulation of the cell cycle.
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Jenkins, Robert H. ORCID: https://orcid.org/0000-0001-8500-9044, Davies, Luke C., Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421, Akiyama, Hideo, Cumbes, Bevan ORCID: https://orcid.org/0000-0001-8529-0040, Beltrami, Cristina, Carrington, Christopher P., Phillips, Aled O. ORCID: https://orcid.org/0000-0001-9744-7113, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342
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miR-192 induces G2/M growth arrest in aristolochic acid nephropathy.
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Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Martin, John, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342
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Pleiotropy of microRNA-192 in the kidney.
Biochemical Society Transactions
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Martin, John, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Bennagi, Rasha, Krupa, Aleksandra, Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342
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Post-transcriptional regulation of transforming growth factor beta-1 by microrna-744.
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Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342
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BMP-6 emerges as a potential major regulator of fibrosis in the kidney [Commentary].
American Journal of Pathology
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Krupa, Aleksandra, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Luo, Dong Dong, Lewis, Aled G., Phillips, Aled Owain ORCID: https://orcid.org/0000-0001-9744-7113 and Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342
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Loss of microRNA-192 promotes fibrogenesis in diabetic nephropathy.
Journal of the American Society of Nephrology
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10.1681/ASN.2009050530
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Kastner, Sabine, Thomas, Gareth John, Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Davies, Malcolm and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496
2007.
Hyaluronan induces the selective accumulation of matrix- and cell-associated proteoglycans by mesangial cells.
American Journal of Pathology
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10.2353/ajpath.2007.070085
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Jenkins, Robert Hywel ORCID: https://orcid.org/0000-0001-8500-9044, Thomas, Gareth John, Williams, John David and Steadman, Robert ORCID: https://orcid.org/0000-0002-1303-2496
2004.
Myofibroblastic differentiation leads to hyaluronan accumulation through reduced hyaluronan turnover.
The Journal of Biological Chemistry
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