Gurney, Mark ORCID: https://orcid.org/0000-0003-1119-6638, Davies, Luke C., Jones, Ruth E., Bart, Valentina M., Jenkins, Robert H. ORCID: https://orcid.org/0000-0001-8500-9044, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421 and Czubala, Magdalena A. ORCID: https://orcid.org/0000-0001-9881-1095
2024.
Lentiviral vector preparation for efficient gene and microRNA modulation of peritoneal cavity tissue-resident macrophages in vivo in mice.
Journal of Visualized Experiments
204
, e64926.
10.3791/64926
|
|
|
Patel, Sarju and Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499
2023.
Essential role of staff development in addressing structural racism.
The Lancet
401
(10393)
, pp. 2036-2037.
10.1016/S0140-6736(23)00127-7
|
|
De, Diana ORCID: https://orcid.org/0000-0002-0182-2837, Nwamadi, Kendra, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 and Patel, Sarju
2023.
Raising awareness of vitamin D: the role of public health initiatives in the promotion of interdisciplinary learning.
Presented at: INHWE 3rd international congress of health education and research & AOME annual academic meeting,
Cardiff,
27-29 June 2023.
|
|
|
Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499
2021.
Data visualization with the programming language R.
Biochemist
43
(5)
, 8–14.
10.1042/bio_2021_174
|
|
|
Alsagaby, Suliman A., Brewis, Ian A., Vijayakumar, Rajendran, Alhumaydhi, Fahad A., Alwashmi, Ameen S., Alharbi, Naif K., Al Abdulmonem, Waleed, Premanathan, Mariappan, Pratt, Guy, Fegan, Christopher ORCID: https://orcid.org/0000-0001-9685-0621, Pepper, Christopher and Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499
2021.
Proteomics-based identification of cancer-associated proteins in chronic lymphocytic leukaemia.
Electronic Journal of Biotechnology
52
, pp. 1-12.
10.1016/j.ejbt.2021.04.006
|
|
|
Allen, Jeff, Basu, Priyadarshini, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Forty, Liz, Goodfellow, Rhian, Mensuch, Linnet, Patel, Sarju and Vyas, Jui ORCID: https://orcid.org/0000-0003-2839-2651
2021.
Submission to Welsh Government Consultation regarding an Anti Racist Wales.
[Documentation].
Cardiff:
Welsh Government.
Available at: https://cf.sharepoint.com/:b:/t/MEDICStudentRaceEq...
|
|
Christakoudi, Sofia, Pagoni, Panagiota ORCID: https://orcid.org/0000-0002-8090-512X, Ferrari, Pietro, Cross, Amanda J., Tzoulaki, Ioanna, Muller, David C., Weiderpass, Elisabete, Freisling, Heinz, Murphy, Neil, Dossus, Laure, Fortner, Renee Turzanski, Agudo, Antonio, Overvad, Kim, Perez-Cornago, Aurora, Key, Timothy J., Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Johansson, Mattias, Tjønneland, Anne, Halkjær, Jytte, Boutron-Ruault, Marie-Christine, Artaud, Fanny, Severi, Gianluca, Kaaks, Rudolf, Schulze, Matthias B., Bergmann, Manuela M., Masala, Giovanna, Grioni, Sara, Simeon, Vittorio, Tumino, Rosario, Sacerdote, Carlotta, Skeie, Guri, Rylander, Charlotta, Borch, Kristin Benjaminsen, Quirós, J. Ramón, Rodriguez-Barranco, Miguel, Chirlaque, Maria-Dolores, Ardanaz, Eva, Amiano, Pilar, Drake, Isabel, Stocks, Tanja, Häggström, Christel, Harlid, Sophia, Ellingjord-Dale, Merete, Riboli, Elio and Tsilidis, Konstantinos K.
2021.
Weight change in middle adulthood and risk of cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.
International Journal of Cancer
148
(7)
, pp. 1637-1651.
10.1002/ijc.33339
|
|
Akinnawonu, Lara, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Mensouh, Linn, Nelson Rowe, Ellen and Patel, Sarju
2021.
Strategies for improving race equality in healthcare institutions.
Presented at: 4rd Developing Excellence in Medical Education conference,
Manchester,
7 December 2021.
|
|
|
Benfield, Eve, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 and Patel, Sarju
2021.
Submission to Welsh Government Consultation LGBTQ+ Action Plan.
Cardiff:
Welsh Government.
|
|
Ipseiz, Natacha ORCID: https://orcid.org/0000-0001-5008-8889, Czubala, Magdalena A. ORCID: https://orcid.org/0000-0001-9881-1095, Bart, Valentina M.T., Davies, Luke C., Jenkins, Robert H. ORCID: https://orcid.org/0000-0001-8500-9044, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 and Taylor, Philip R. ORCID: https://orcid.org/0000-0003-0163-1421
2020.
Effective in vivo gene modification in mouse tissue-resident peritoneal macrophages by intraperitoneal delivery of lentiviral vectors.
Molecular Therapy - Methods and Clinical Development
16
, pp. 21-31.
10.1016/j.omtm.2019.10.004
|
|
|
Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499
2018.
drawProteins, package to draw protein schematics from Uniprot API output.
Bioconductor.
|
|
Alsagaby, Suliman A., Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 and Pepper, Christopher
2016.
Key molecular drivers of chronic lymphocytic leukemia.
Clinical Lymphoma, Myeloma and Leukemia
16
(11)
, pp. 593-606.
10.1016/j.clml.2016.08.008
|
|
Welton, Joanne Louise, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Gurney, Mark ORCID: https://orcid.org/0000-0003-1119-6638, Webber, Jason Paul ORCID: https://orcid.org/0000-0003-4772-3014, Spary, Lisa Kate, Gil Carton, David, Falcón-Pérez, Juan Manuel, Walton, Sean Peter, Mason, Malcolm David ORCID: https://orcid.org/0000-0003-1505-2869, Tabi, Zsuzsanna and Clayton, Aled ORCID: https://orcid.org/0000-0002-3087-9226
2016.
Proteomics analysis of vesicles isolated from plasma and urine of prostate cancer patients using a multiplex, aptamer-based protein array.
Journal of Extracellular Vesicles
5
, 31209.
10.3402/jev.v5.31209
|
|
|
Walsby, Elisabeth ORCID: https://orcid.org/0000-0001-8523-5017, Buggins, Andrea, Devereux, Stephen, Jones, Ceri, Pratt, Guy, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Fegan, Chris ORCID: https://orcid.org/0000-0001-9685-0621 and Pepper, Chris
2014.
Development and characterization of a physiologically relevant model of lymphocyte migration in chronic lymphocytic leukemia.
Blood
123
(23)
, pp. 3607-3617.
10.1182/blood-2013-12-544569
|
|
Alsagaby, Suliman A., Khanna, Sanjay, Hart, Keith, Pratt, Guy, Fegan, Christopher ORCID: https://orcid.org/0000-0001-9685-0621, Pepper, Christopher, Brewis, Ian and Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499
2014.
Proteomics-based strategies to identify proteins relevant to chronic lymphocytic leukemia.
Journal of Proteome Research
13
(11)
, pp. 5051-5062.
10.1021/pr5002803
|
|
Wong, Ryan Francis, Pepper, Christopher John, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Nagorsen, Dirk, Man, Stephen Tzekwung ORCID: https://orcid.org/0000-0001-9103-1686 and Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621
2013.
Blinatumomab induces autologous T cell killing of chronic lymphocytic leukemia cells.
Haematologica
98
(12)
, pp. 1930-1938.
10.3324/haematol.2012.082248
|
|
Hoogendoorn, Bastiaan ORCID: https://orcid.org/0000-0001-9753-169X, Berube, Kelly Ann ORCID: https://orcid.org/0000-0002-7471-7229, Gregory, Clive James ORCID: https://orcid.org/0000-0003-4876-3982, Jones, Timothy Peter ORCID: https://orcid.org/0000-0002-4466-1260, Sexton, Keith John, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Brewis, Ian Andrew, Murison, Alexander James, Arthur, Robert Alan, Price, Heather Dawn, Morgan, Huw and Matthews, Ian Price
2012.
Gene and protein responses of human lung tissue explants exposed to ambient particulate matter of different sizes.
Inhalation Toxicology
24
(14)
, pp. 966-975.
10.3109/08958378.2012.742600
|
|
Hamilton, Emma, Pearce, Laurence, Morgan, Liam ORCID: https://orcid.org/0000-0002-7571-6025, Robinson, Sophie, Ware, Victoria Lesley, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Thomas, N. Shaun B., Yallop, Deborah, Devereux, Stephen, Fegan, Christopher D. ORCID: https://orcid.org/0000-0001-9685-0621, Buggins, Andrea G. S. and Pepper, Christopher John
2012.
Mimicking the tumour microenvironment: three different co-culture systems induce a similar phenotype but distinct proliferative signals in primary chronic lymphocytic leukaemia cells.
British Journal of Haematology
158
(5)
, pp. 589-599.
10.1111/j.1365-2141.2012.09191.x
|
|
Masgras, I., Carrera, S., de Verdier, P. J., Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Majid, A., Makhtar, W., Tulchinsky, E., Jones, G. D. D., Roninson, I. B. and Macip, S.
2012.
Reactive oxygen species and mitochondrial sensitivity to oxidative stress determine induction of cancer cell death by p21.
Journal of Biological Chemistry
287
(13)
, pp. 9845-9854.
10.1074/jbc.M111.250357
|
|
Pepper, Christopher John, Majid, Aneela, Lin, Thet Thet, Hewamana, Saman, Pratt, Guy, Walewska, Renata, Gesk, Stefan, Siebert, Reiner, Wagner, Simon, Kennedy, Ben, Miall, Fiona, Davis, Zadie A., Tracy, Ian, Gardiner, Anne C., Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Dyer, Martin J. S., Oscier, David and Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621
2012.
Defining the prognosis of early stage chronic lymphocytic leukaemia patients.
British Journal of Haematology
156
(4)
, pp. 499-507.
10.1111/j.1365-2141.2011.08974.x
|
|
Pepper, Christopher John, Mahdi, J. G., Buggins, A. G. S., Hewamana, Saman, Walsby, Elisabeth Jane ORCID: https://orcid.org/0000-0001-8523-5017, Mahdi, Eamon, Al-Haza'a, A., Mahdi, Ali J., Lin, Thet Thet, Pearce, Laurence, Morgan, Liam David ORCID: https://orcid.org/0000-0002-7571-6025, Bowen, Ivor D., Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 and Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621
2011.
Two novel aspirin analogues show selective cytotoxicity in primary chronic lymphocytic leukaemia cells that is associated with dual inhibition of Rel A and COX-2.
Cell Proliferation
44
(4)
, pp. 380-390.
10.1111/j.1365-2184.2011.00760.x
|
|
Pearce, Laurence, Morgan, Liam David ORCID: https://orcid.org/0000-0002-7571-6025, Lin, Thet Thet, Hewamana, Saman, Matthews, Reginald James, Deaglio, Silvia, Rowntree, Clare, Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621, Pepper, Christopher John and Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499
2010.
Genetic modification of primary chronic lymphocytic leukemia cells with a lentivirus expressing CD38.
Haematologica
95
(3)
, pp. 514-517.
10.3324/haematol.2009.014381
|
|
Tediose, Teeo, Kolev, Martin Veselinov ORCID: https://orcid.org/0000-0002-7208-3875, Baalasubramanian, Sivasankar, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Donev, Rossen Mintchev
2010.
Interplay between REST and nucleolin transcription factors: a key mechanism in the overexpression of genes upon increased phosphorylation [RETRACTED].
Nucleic Acids Research
38
(9)
, pp. 2799-2812.
10.1093/nar/gkq013
|
|
Vaisitti, T., Aydin, S., Rossi, D., Cottino, F., Bergui, L., D'Arena, G., Bonello, L., Horenstein, A. L., Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Pepper, Christopher John, Gaidano, G., Malavasi, F. and Deaglio, S.
2010.
CD38 increases CXCL12-mediated signals and homing of chronic lymphocytic leukemia cells.
Leukemia
24
(5)
, pp. 958-969.
10.1038/leu.2010.36
|
|
Alnagar, Fahima, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 and Brewis, Ian Andrew
2010.
Bicarbonate-dependent serine/threonine protein dephosphorylation in capacitating boar spermatozoa.
Journal of Andrology
31
(4)
, pp. 393-405.
10.2164/jandrol.109.008383
|
|
Brewis, Ian and Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499
2010.
Proteomics technologies for the global identification and quantification of proteins.
Donev, Rossen, ed.
Advances in Protein Chemistry and Structural Biology,
Vol. 80.
Elsevier,
pp. 1-44.
(10.1016/B978-0-12-381264-3.00001-1)
|
|
Watkins, Catherine Louise, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621, Takayama, Kentaro, Nakase, Ikuhiko, Futaki, Shiroh and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905
2009.
Cellular uptake, distribution and cytotoxicity of the hydrophobic cell penetrating peptide sequence PFVYLI linked to the proapoptotic domain peptide PAD.
Journal of Controlled Release
140
(3)
, pp. 237-244.
10.1016/j.jconrel.2009.04.028
|
|
Pepper, Christopher John, Hewamana, Saman, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 and Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621
2009.
NF-κB as a prognostic marker and therapeutic target in chronic lymphocytic leukemia.
Future Oncology
5
(7)
, pp. 1027-1037.
10.2217/fon.09.72
|
|
McLaren, James Edward ORCID: https://orcid.org/0000-0002-7021-5934, Zuo, Jianmin, Grimstead, Julia W., Poghosyan, Zaruhi ORCID: https://orcid.org/0000-0003-4966-7618, Bell, Andrew I., Rowe, Martin and Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499
2009.
STAT1 contributes to the maintenance of the latency III viral programme observed in Epstein-Barr virus-transformed B cells and their recognition by CD8+ T cells.
Journal of General Virology
90
(9)
, pp. 2239-2250.
10.1099/vir.0.011627-0
|
|
Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Shore, Angharad M., Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Hewamana, Saman, Jones, Catrin M., Giles, Peter James ORCID: https://orcid.org/0000-0003-3143-6854, Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621, Pepper, Christopher John and Brewis, Ian Andrew
2009.
Quantitative nuclear proteomics reveals new phenotypes altered in lymphoblastoid cells.
Proteomics - Clinical Applications
3
(3)
, pp. 359-369.
10.1002/prca.200800137
|
|
Hewamana, Saman, Lin, Thet Thet, Rowntree, Clare, Karunanithi, Kamaraj, Pratt, Guy, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 and Pepper, Christopher John
2009.
Rel A is an independent biomarker of clinical outcome in chronic lymphocytic leukemia.
Journal of Clinical Oncology
27
(5)
, pp. 763-769.
10.1200/JCO.2008.19.1114
|
|
Raby, Anne-Catherine ORCID: https://orcid.org/0000-0002-5354-5835, Le Bouder, Emmanuel, Colmont, Chantal Sophie, Davies, James Anthony ORCID: https://orcid.org/0000-0003-3569-4500, Richards, Peter, Coles, Barbara, George, Christopher H., Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Topley, Nicholas and Labeta, Mario Oscar ORCID: https://orcid.org/0000-0001-5750-6983
2009.
Soluble TLR2 reduces inflammation without compromising bacterial clearance by disrupting TLR2 triggering.
The Journal of Immunology
183
(1)
, pp. 506-517.
10.4049/jimmunol.0802909
|
|
Hewamana, Saman, Lin, Thet Thet, Jenkins, Chris, Burnett, Alan Kenneth, Jordan, Craig T., Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Rowntree, Clare and Pepper, Christopher John
2008.
The novel nuclear factor- B inhibitor LC-1 is equipotent in poor prognostic subsets of chronic lymphocytic leukemia and shows strong synergy with fludarabine.
Clinical Cancer Research
14
(24)
, pp. 8102-8111.
10.1158/1078-0432.CCR-08-1673
|
|
Pepper, Christopher John, Lin, Thet Thet, Pratt, Guy, Hewamana, Saman, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Hiller, Louise, Hills, Robert Kerrin ORCID: https://orcid.org/0000-0003-0166-0062, Ward, Rachel, Starczynski, Jane, Austen, Belinda, Hooper, Laura, Stankovic, Tatjana and Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621
2008.
Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers.
Blood
112
(9)
, pp. 3807-3817.
10.1182/blood-2008-05-157131
|
|
Hewamana, Saman, Alghazal, Suhair Alkailani, Lin, Thet Thet, Clement, Matthew ORCID: https://orcid.org/0000-0002-9280-5281, Jenkins, Christopher, Guzman, Monica L., Jordan, Craig T., Neelakantan, Sundar, Crooks, Peter A., Burnett, Alan Kenneth, Pratt, Guy, Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621, Rowntree, Clare, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 and Pepper, Christopher John
2008.
The NF-κB subunit Rel A is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukemia and represents a promising therapeutic target.
Blood
111
(9)
, pp. 4681-4689.
10.1182/blood-2007-11-125278
|
|
Chong, Lee Kien, Aicheler, Rebecca, Llewellyn-Lacey, Sian, Tomasec, Peter, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 and Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964
2008.
Proliferation and interleukin 5 production by CD8hiCD57+ T cells.
European Journal of Immunology
38
(4)
, pp. 995-1000.
10.1002/eji.200737687
|
|
Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499
2008.
Duplication: most cases on database are innocent [Letter].
Nature
452
(7183)
, p. 29.
10.1038/452029d
|
|
Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Donev, Rossen Mintchev and Hewamana, Saman
2008.
Targeting transcription factors for therapeutic benefit.
Molecular Biosystems
4
(9)
, pp. 909-919.
10.1039/b801920g
|
|
McLaren, James Edward ORCID: https://orcid.org/0000-0002-7021-5934, Rowe, Martin and Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499
2007.
Epstein-Barr virus induces a distinct form of DNA-bound STAT1 compared with that found in interferon-stimulated B lymphocytes.
Journal of General Virology
88
(7)
, pp. 1876-1886.
10.1099/vir.0.82741-0
|
|
Pepper, Christopher John, Ward, R., Lin, Thet Thet, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Starczynski, J., Musson, M., Rowntree, Claire, Bentley, P., Mills, K., Pratt, G. and Fegan, Christopher Daniel ORCID: https://orcid.org/0000-0001-9685-0621
2007.
Highly purified CD38+ and CD38- sub-clones derived from the same chronic lymphocytic leukemia patient have distinct gene expression signatures despite their monoclonal origin.
Leukemia
21
(4)
, pp. 687-696.
10.1038/sj.leu.2404587
|
|
Shore, Angharad M., White, Paul Charles ORCID: https://orcid.org/0000-0002-6562-4696, Hui, Rosaline C.-Y., Essafi, Abdelkader, Lam, Eric W.-F., Rowe, Martin and Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499
2006.
Epstein-Barr virus represses the FoxO1 transcription factor through latent membrane protein 1 and latent membrane protein 2A.
Journal of Virology
80
(22)
, pp. 11191-11199.
10.1128/JVI.00983-06
|
|
|
White, Paul Charles ORCID: https://orcid.org/0000-0002-6562-4696, Shore, A. M., Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, McLaren, James Edward ORCID: https://orcid.org/0000-0002-7021-5934, Soeiro, I., Lam, E. W.-F. and Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499
2006.
Regulation of cyclin D2 and the cyclin D2 promoter by protein kinase A and CREB in lymphocytes.
Oncogene
25
(15)
, pp. 2170-2180.
10.1038/sj.onc.1209255
|
|
Omidvar, Nader, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Longhi, M. Paula, Smith, Richard A. G. and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676
2006.
Expression of glycosylphosphatidylinositol-anchored CD59 on target cells enhances human NK cell-mediated cytotoxicity.
Journal of immunology
176
(5)
, pp. 2915-2923.
|
|
Omidvar, Nader, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Longhi, Maria P., Smith, Richard A. G. and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676
2006.
Expression of glycosylphosphatidylinositol-anchored CD59 on target cells enhances human NK cell-mediated cytotoxicity.
The Journal of Immunology
176
(5)
, pp. 2915-2923.
10.4049/jimmunol.176.5.2915
|
|
Pepper, Christopher John, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Alghazal, S., Ward, R., Pratt, G., Starczynski, J., Lin, Thet Thet and Rowntree, C.
2006.
CD38+ chronic lymphocytic leukaemia cells co-express high levels of ZAP-70 and are functionally distinct from their CD38− counter-parts.
Leukemia
20
(4)
, pp. 743-744.
10.1038/sj.leu.2404133
|
|
Siebert, Stefan, Fielding, Ceri A. ORCID: https://orcid.org/0000-0002-5817-3153, Williams, Bryan D. and Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499
2005.
Mutation of the extracellular domain of tumour necrosis factor receptor 1 causes reduced NF‐κB activation due to decreased surface expression.
FEBS Letters
579
(23)
, pp. 5193-5198.
10.1016/j.febslet.2005.08.037
|
|
Siebert, Stefa, Williams, Bryan D. and Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499
2005.
Reply [Letter].
Arthritis & Rheumatism
52
(9)
, pp. 2952-2953.
10.1002/art.21369
|
|
Richardson, Ciaran Joseph, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Powell, Martin B., Prince, Stuart N., Chen, Yun-Hsiang, Spiller, O. Brad and Rowe, Martin
2005.
Susceptibility of B lymphocytes to adenovirus type 5 infection is dependent upon both coxsackie-adenovirus receptor and αvβ5 integrin expression.
Journal of General Virology
86
(6)
, pp. 1669-1679.
10.1099/vir.0.80806-0
|
|
Siebert, Stefan, Amos, Nick, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Aksentijevich, Ivona, Williams, Bryan Davies and Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499
2005.
Reduced tumor necrosis factor signaling in primary human fibroblasts containing a tumor necrosis factor receptor superfamily 1A mutant.
Arthritis & Rheumatism
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10.1002/art.20955
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Breslin, Elaine M., White, Paul ORCID: https://orcid.org/0000-0002-6562-4696, Shore, Angharad M., Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281 and Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499
2005.
LY294002 and rapamycin co-operate to inhibit T-cell proliferation.
British Journal of Pharmacology
144
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, pp. 791-800.
10.1038/sj.bjp.0706061
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Sathish, Jean Gerard, Walters, Jenna, Luo, Jin Cai, Johnson, Kenneth G., LeRoy, Frances Gertrude, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Kim, Kwang P., Gygi, Steven P., Neel, Benjamin G. and Matthews, Reginald James
2004.
CD22 is a functional ligand for SH2 domain-containing protein-tyrosine phosphatase-1 in primary T cells.
Journal of Biological Chemistry
279
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, pp. 47783-47791.
10.1074/jbc.M402354200
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Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Siebert, Stefan, Rowe, Martin and Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499
2004.
Analysis of human tumour necrosis factor receptor 1 dominant-negative mutants reveals a major region controlling cell surface expression.
FEBS Letters
570
(1-3)
, pp. 138-142.
10.1016/j.febslet.2004.06.035
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Moutaftsi, Magdalena, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Spector, Stephen A. and Tabi, Zsuzsanna
2004.
Impaired lymphoid chemokine-mediated migration due to a block on the chemokine receptor switch in human cytomegalovirus-infected dendritic cells.
Journal of Virology
78
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, pp. 3046-3054.
10.1128/JVI.78.6.3046-3054.2004
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Burchill, M. A., Goetz, C. A., Prlic, M., O'Neil, J. J., Harmon, I. R., Bensinger, S. J., Turka, L. A., Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Jameson, S. C. and Farrar, M. A.
2003.
Distinct effects of STAT5 activation on CD4(+) and CD8(+) T cell homeostasis: Development of CD4(+)CD25(+) regulatory T cells versus CD8(+) memory T cells.
The Journal of Immunology
171
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, pp. 5853-5864.
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Richardson, Ciaran Joseph, Fielding, Ceri ORCID: https://orcid.org/0000-0002-5817-3153, Rowe, Martin and Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499
2003.
Epstein-Barr virus regulates STAT1 through latent membrane protein 1.
Journal of Virology
77
(7)
, pp. 4439-4443.
10.1128/JVI.77.7.4439-4443.2003
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Ohtani, Naoko, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Gaubatz, Stefan, Sanij, Elaine, Hertzog, Paul, Wolvetang, Ernst, Ghysdael, Jacques, Rowe, Martin and Hara, Eiji
2003.
Epstein-Barr virus LMP1 blocks p16INK4a-RB pathway by promoting nuclear export of E2F4/5.
Journal of cell biology
162
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, p. 173.
10.1083/jcb.200302085
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Prince, S., Keating, S., Fielding, C., Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Floettmann, E. and Rowe, Martin
2003.
Latent membrane protein 1 inhibits Epstein-Barr virus lytic cycle induction and progress via different mechanisms.
Journal of Virology
77
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, pp. 5000-5007.
10.1128/JVI.77.8.5000-5007.2003
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Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Mehl, Anja Maria, Jones, Matt and Rowe, Martin
2002.
Phosphatidylinositol 3-kinase is essential for the proliferation of lymphoblastoid cells.
Oncogene
21
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, pp. 1263-1271.
10.1038/sj.onc.1205182
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Saitoh, Masao, Pullen, Nicholas, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Cantrell, Doreen, Dennis, Patrick B and Thomas, George
2002.
Regulation of an activated S6 kinase 1 variant reveals a novel mammalian target of rapamycin phosphorylation site.
Journal of Biological Chemistry
277
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, 20104-20112..
10.1074/jbc.M201745200
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Sathish, Jean Gerard, Johnson, Kenneth G., LeRoy, Frances Gertrude, Fuller, Kerenza J., Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Borysiewicz, Leszek, Sims, Martin J. and Matthews, Reginald James
2001.
Requirement for CD28 co-stimulation is lower in SHP-1-deficient T cells.
European Journal of Immunology
31
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, pp. 3649-3658.
10.1002/1521-4141(200112)31:12<3649::AID-IMMU3649>3.0.CO;2-8
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Mehl, Anja Maria, Jones, Matthew, Rowe, Martin and Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499
2001.
Characterization of a CD40-dominant inhibitory receptor mutant.
The Journal of Immunology
167
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, pp. 6388-6393.
|
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Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Sandvej, Kristian, Mehl, Anja Maria, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Jones, Matthew and Rowe, Martin
2001.
Epstein-Barr virus LMP-1 natural sequence variants differ in their potential to activate cellular signaling pathways.
Journal of Virology
75
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, pp. 9129-9141.
10.1128/JVI.75.19.9129-9141.2001
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Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499
2001.
Signalling events regulating lymphoid growth and survival.
Seminars in Cancer Biology
11
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, pp. 415-421.
10.1006/scbi.2001.0408
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Mehl, Anja M., Floettmann, J. Eike, Jones, Matthew, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 and Rowe, Martin
2001.
Characterization of intercellular adhesion molecule-1 regulation by Epstein-Barr virus-encoded latent membrane protein-1 identifies pathways that cooperate with nuclear factor κB to activate transcription.
Journal of Biological Chemistry
276
(2)
, pp. 984-992.
10.1074/jbc.M003758200
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Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 and Astoul, E.
2001.
Applications of green fluorescent protein in cell signaling.
O'Neill, Luke A. J. and Bowie, Andrew, eds.
Interleukin Protocols,
Vol. 60.
Methods in Molecular Medicine,
vol. 60.
Totowa, New Jersey:
Humana Press,
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Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 and Athie-Morales, Veronica
2001.
Analysis of interleukin-2 signaling using affinity precipitations and polyacrylamide gel electrophoresis.
O'Neill, Luke A. J. and Bowie, Andrew, eds.
Interleukin protocols,
Vol. 60.
Methods in Molecular Medicine,
vol. 60.
New Jersey:
Humana Press,
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Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Floettman, J. Eike, Mehl, Anja, Jones, Matthew and Rowe, Martin
2001.
Mechanism of action of a novel latent membrane protein-1 dominant negative.
Journal of Biological Chemistry
276
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10.1074/jbc.M005461200
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Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Babbage, J. W., Thomas, G. and Cantrell, D.
1999.
p70s6k integrates phosphatidylinositol 3-Kinase and rapamycin-regulated signals for E2F regulation in T lymphocytes.
Molecular and Cellular Biology
19
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, pp. 4729-4738.
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Vanhaesebroeck, Bart, Higashi, Kyochiro, Raven, Catherine, Welham, Melanie, Anderson, Simon, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Ward, Stephen G. and Waterfield, Michael D.
1999.
Autophosphorylation of p110δ phosphoinositide 3‐kinase: a new paradigm for the regulation of lipid kinases in vitro and in vivo.
The EMBO Journal
18
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, pp. 1292-1302.
10.1093/emboj/18.5.1292
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Arrieumerlou, C., Donnadieu, E., Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Keryer, G., Bismuth, G., Cantrell, D. and Trautmann, A.
1998.
Involvement of phosphoinositide 3-kinase and Rac in membrane ruffling induced by IL-2 in T cells.
European Journal of Immunology
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, pp. 1877-1885.
10.1002/(SICI)1521-4141(199806)28:06<1877::AID-IMMU1877>3.0.CO;2-I
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Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 and O'Neill, Luke A. J.
1998.
Inhibition of nuclear factor kB by direct modification in whole cells mechanism of action of nordihydroguaiaritic acid, curcumin and thiol modifiers.
Biochemical Pharmacology
55
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10.1016/S0006-2952(97)00535-2
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Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499, Babbage, Jane W., Burgering, Boudewijn M. T., Groner, Bernd, Reif, Karin and Cantrell, Doreen A.
1997.
Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F.
Immunity
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10.1016/S1074-7613(00)80388-X
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Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 and O'Neill, L. A. J.
1996.
2-Mercaptoethanol restores the ability of nuclear factor kB (NFkB) to bind DNA in nuclear extracts from interleukin 1-treated cells incubated with pyrollidine dithiocarbamate (PDTC).
Biochemical Journal -London-
320
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Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 and O'Neill, L. A.
1995.
Effects of oxidants and antioxidants on nuclear factor kappa B activation in three different cell lines: evidence against a universal hypothesis involving oxygen radicals.
Acta Biochimica et Biophysica
1260
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10.1016/0167-4781(94)00186-7
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