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      HGF/SF promotes an aggressive phenotype in c-Met-overexpressing fulvestrant-resistant MCF-7 cells - Evidence for MMP-9 and PI3k involvement [Abstract].
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|   | 
| Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Jordan, Nicola Jane, Morgan, Liam David  ORCID: https://orcid.org/0000-0002-7571-6025, Green, T. P. and Nicholson, Robert Ian
      2007.
      
      Src kinase promotes adhesion-independent activation of FAK and enhances cellular migration in tamoxifen-resistant breast cancer cells.
      Clinical & Experimental Metastasis
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      10.1007/s10585-007-9065-y | 
|   | 
| Nicholson, Robert Ian, Hutcheson, Iain Robert, Jones, H. E., Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Giles, M., Taylor, Kathryn Mary  ORCID: https://orcid.org/0000-0002-9576-9490 and Gee, Julia Margaret Wendy  ORCID: https://orcid.org/0000-0001-6483-2015
      2007.
      
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      10.1007/s11154-007-9033-5 | 
|   | 
| Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Green, T. P., Smith, Chris, James, M., Jordan, Nicola Jane and Nicholson, Robert Ian
      2007.
      
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      , 3411S. | 
|   | 
| Gee, Julia Margaret Wendy  ORCID: https://orcid.org/0000-0001-6483-2015, Shaw, Victoria E., Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, McClelland, Richard Andrew, Rushmere, N. K. and Nicholson, Robert Ian
      2006.
      
      Deciphering antihormone-induced compensatory mechanisms in breast cancer and their therapeutic implications.
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      , S77-S88.
      
      10.1677/erc.1.01274 | 
|   | 
| Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Morgan, Liam David  ORCID: https://orcid.org/0000-0002-7571-6025, Green, Tim and Nicholson, Robert
      2006.
      
      Src as a therapeutic target in anti-hormone/anti-growth factor-resistant breast cancer.
      Endocrine-Related Cancer
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      10.1677/erc.1.01297 | 
|   | 
| Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Jordan, Nicola Jane, Jiang, Wen Guo  ORCID: https://orcid.org/0000-0002-3283-1111, Harper, Maureen Elaine, McClelland, Richard, Smith, Chris and Nicholson, Robert
      2006.
      
      Chronic exposure to fulvestrant promotes overexpression of the c-Met receptor in breast cancer cells: implications for tumour-stroma interactions.
      Endocrine-Related Cancer
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      10.1677/erc.1.01270 | 
|   | 
| Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Morgan, Liam David  ORCID: https://orcid.org/0000-0002-7571-6025, Green, Tim P., Barrow, Denise, Gee, Julia Margaret Wendy  ORCID: https://orcid.org/0000-0001-6483-2015 and Nicholson, Robert Ian
      2006.
      
      Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells.
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      10.1007/s10549-005-9120-9 | 
|   | 
| Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Jiang, Wen Guo  ORCID: https://orcid.org/0000-0002-3283-1111, Obermeier, Kathrin, Taylor, Kathryn Mary  ORCID: https://orcid.org/0000-0002-9576-9490, Morgan, Liam David  ORCID: https://orcid.org/0000-0002-7571-6025, Burmi, Rajpal Singh, Barrow, Denise and Nicholson, Robert Ian
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      Tamoxifen-resistance in MCF7 cells promotes EMT-like behaviour and involves modulation of [beta]-catenin phosphorylation.
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      10.1002/ijc.21355 | 
|   | 
| Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Green, T. P. and Nicholson, R. I.
      2006.
      
      Combination therapy using AZD0530 and tamoxifen prevents antihormone resistance in breast cancer cells.
      Breast Cancer Research and Treatment
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      , S246-S246. | 
|   | 
| Nicholson, Robert Ian, Hutcheson, Iain Robert, Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Knowlden, Janice Mary, Giles, Martin Gwyn, Barrow, Denise and Gee, Julia Margaret Wendy  ORCID: https://orcid.org/0000-0001-6483-2015
      2005.
      
      Growth factor signalling and resistance to selective oestrogen receptor modulators and pure anti-oestrogens: the use of anti-growth factor therapies to treat or delay endocrine resistance in breast cancer.
      Endocrine-Related Cancer
      12
      
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      , S29-S36.
      
      10.1677/erc.1.00991 | 
|   | 
| Nicholson, Robert Ian, Hutcheson, Iain Robert, Britton, David James, Knowlden, Janice Mary, Jones, Helen E., Harper, Maureen Elaine, Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Barrow, Denise and Gee, Julia Margaret Wendy  ORCID: https://orcid.org/0000-0001-6483-2015
      2005.
      
      Growth factor signalling networks in breast cancer and resistance to endocrine agents: new therapeutic strategies.
      The Journal of Steroid Biochemistry and Molecular Biology
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      10.1016/j.jsbmb.2004.12.006 | 
|   | 
| Taylor, Kathryn Mary  ORCID: https://orcid.org/0000-0002-9576-9490, Vichova, Petra, Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702 and Nicholson, Robert
      2005.
      
      Zinc-dependant stimulation of Src, EGFR and IGFR signalling pathways in tamoxifen-resistant breast cancer and the role of zinc transporters.
      Breast Cancer Research and Treatment
      94
      
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      , S162-S162. | 
|   | 
| Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Harper, Maureen Elaine, Jiang, Wen Guo  ORCID: https://orcid.org/0000-0002-3283-1111, McClelland, Richard and Nicholson, Robert
      2005.
      
      Elevated c-met expression accompanies endocrine resistance in MCF7 breast cancer cells and promotes in vitro cell migration and invasion.
      Breast Cancer Research and Treatment
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|   | 
| Jones, Helen E., Goddard, Lindy, Gee, Julia Margaret Wendy  ORCID: https://orcid.org/0000-0001-6483-2015, Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Rubini, M., Barrow, Denise, Knowlden, Janice Mary, Williams, Sophie E., Wakeling, A. E. and Nicholson, Robert Ian
      2004.
      
      Insulin-like growth factor-1 receptor signalling and acquired resistance to gefitinib (ZD1839; Iressa) in human breast and prostate cancer cells.
      Endocrine-Related Cancer
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      , pp. 793-814.
      
      10.1677/erc.1.00799 | 
|   | 
| Taylor, Kathryn Mary  ORCID: https://orcid.org/0000-0002-9576-9490, Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702 and Nicholson, Robert
      2004.
      
      Zinc transporter LIV-1: a link between cellular development and cancer progression.
      Trends in Endocrinology and Metabolism
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      , pp. 461-463. | 
|   | 
| Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Morgan, Liam David  ORCID: https://orcid.org/0000-0002-7571-6025, Barrow, Denise, Dutkowski, Carol Mary, Wakeling, Alan and Nicholson, Robert Ian
      2004.
      
      Tamoxifen resistance in breast cancer cells is accompanied by an enhanced motile and invasive phenotype: inhibition by gefitinib ('Iressa', ZD1839).
      Clinical & Experimental Metastasis
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      , pp. 201-212.
      
      10.1023/B:CLIN.0000037697.76011.1d | 
|   | 
| Nicholson, Robert, Hutcheson, Iain Robert, Knowlden, Janice Mary, Jones, Helen E., Harper, Maureen Elaine, Jordan, Nicola Jane, Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Barrow, Denise and Gee, Julia Margaret Wendy  ORCID: https://orcid.org/0000-0001-6483-2015
      2004.
      
      Nonendocrine pathways and endocrine resistance: observations with antiestrogens and signal transduction inhibitors in combination.
      Clinical Cancer Research
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      , 346s-354s.
      
      10.1158/1078-0432.CCR-031206 | 
|   | 
| Nicholson, Robert, Hutcheson, Iain Robert, Knowlden, Janice Mary, Britton, David James, Harper, Maureen Elaine, Jordan, Nicola Jane, Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Barrow, Denise and Gee, Julia Margaret Wendy  ORCID: https://orcid.org/0000-0001-6483-2015
      2004.
      Chapter 16: beyond antihormones in the targeted therapy of breast cancer.
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      Endocrine Therapy for Breast Cancer Proceedings of the 2003 Gleneagles Conference,
       
      
      
      
       
      New York: 
      Marcel Dekker,
      pp. 249-258. | 
|   | 
| Nicholson, Robert Ian, Jones, Helen E., Gee, Julia Margaret Wendy  ORCID: https://orcid.org/0000-0001-6483-2015, Barrow, Denise, Hiscox, Stephen Eward  ORCID: https://orcid.org/0000-0003-0105-2702, Harper, Maureen Elaine, Rubini, M., Guy, S. and Wakeling, A. E.
      2003.
      
      Insulin-like growth factor-1 receptor signalling and acquired resistance to gefitinib ('Iressa', ZD1839) in MCF-7 human breast cancer cells [Abstract].
      Breast Cancer Research and Treatment
      82
      
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      , S171.
      
      10.1023/A:1026252325164 | 
|   | 
| Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Hallett, Maurice Bartlett  ORCID: https://orcid.org/0000-0001-8197-834X, Morgan, Bryan Paul  ORCID: https://orcid.org/0000-0003-4075-7676 and Van Den Berg, Carmen Wilma
      2002.
      
      GPI-anchored GFP signals Ca2+ but is homogeneously distributed on the cell surface.
      Biochemical and Biophysical Research Communications
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      , pp. 714-721.
      
      10.1016/S0006-291X(02)00280-2 | 
|   | 
| Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702 and Van Den Berg, Carmen Wilma
      2001.
      
      Characterisation of cell activation through cyt2 and cyt1 tail of MCP.
      Molecular Immunology
      38
      
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|   | 
| Parr, C., Davies, G., Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Nakamura, T., Matsumoto, K., Jiang, Wen Guo  ORCID: https://orcid.org/0000-0002-3283-1111 and Mansel, Robert Edward  ORCID: https://orcid.org/0000-0002-8051-0726
      2001.
      
      Inhibition of HGF/SF-induced cell-matrix adhesion, invasion, migration & paxillin phosphorylation, in prostate cancer by the HGF/SF antagonist, NK4.
      British Journal of Cancer
      85
      
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      10.1054/bjoc.2001.1918 | 
|   | 
| Stead, Paul, Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Robinson, Phil S., Pike, Nicholas B., Sidebottom, Philip J., Roberts, Andrew D., Taylor, Nicholas L., Wright, Amy E., Pomponi, Shirley A. and Langley, David
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      Eryloside F, a novel penasterol disaccharide possessing potent thrombin receptor antagonist activity.
      Biorganic and Medicinal Chemistry Letters
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      , pp. 661-664. | 
|   | 
| Parr, Christian, Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Nakamura, Toshikazu, Matumoto, Kunio and Jiang, Wen Guo  ORCID: https://orcid.org/0000-0002-3283-1111
      2000.
      
      NK4, a new HGF/SF variant, is an antagonist to the influence of HGF/SF on the motility and invasion of colon cancer cells.
      International Journal of Cancer
      85
      
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      , pp. 563-570.
      
      10.1002/(SICI)1097-0215(20000215)85:4<563::AID-IJC19>3.0.CO;2-D | 
|   | 
| Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Parr, Christian, Nakamura, Toshikazu, Matsumoto, Kunio, Jiang, Wen Guo  ORCID: https://orcid.org/0000-0002-3283-1111 and Mansel, Robert Edward  ORCID: https://orcid.org/0000-0002-8051-0726
      2000.
      
      Inhibition of HGF/SF-induced breast cancer cell motility and invasion by the HGF/SF variant, NK4.
      British Journal of Cancer
      59
      
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      , pp. 245-254.
      
      10.1023/A:1006348317841 | 
|   | 
| Jiang, Wen Guo  ORCID: https://orcid.org/0000-0002-3283-1111, Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Parr, Christian, Martin, Tracey Amanda  ORCID: https://orcid.org/0000-0003-2690-4908, Matsumoto, Kunio, Nakamura, Toshikazu and Mansel, Robert Edward  ORCID: https://orcid.org/0000-0002-8051-0726
      1999.
      
      Antagonistic effect of NK4, a novel hepatocyte growth factor variant, on in vitro angiogenesis of human vascular endothelial cells.
      Clinical Cancer Research
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      , pp. 3695-3703. | 
|   | 
| Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702 and Jiang, Wen Guo  ORCID: https://orcid.org/0000-0002-3283-1111
      1999.
      
      Ezrin regulates cell-cell and cell-matrix adhesion, a possible role with E-cadherin/beta-catenin.
      Journal of Cell Science
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      , pp. 3081-3090. | 
|   | 
| Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702 and Jiang, Wen Guo  ORCID: https://orcid.org/0000-0002-3283-1111
      1999.
      
      Association of the HGF/SF receptor, c-met, with the cell-surface adhesion molecule, E-cadherin, and catenins in human tumor cells.
      Biochemical and Biophysical Research Communications
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      , pp. 406-411.
      
      10.1006/bbrc.1999.1002 | 
|   | 
| Jiang, Wen Guo  ORCID: https://orcid.org/0000-0002-3283-1111, Hiscox, Stephen  ORCID: https://orcid.org/0000-0003-0105-2702, Matsumoto, Kunio and Nakamura, Toshikazu
      1999.
      
      Hepatocyte growth factor/scatter factor, its molecular, cellular and clinical implications in cancer.
      Critical Reviews in Oncology/Hematology
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      , pp. 209-248. | 
|   | 
| Davies, G., Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Llaffafian, I., Jiang, Wen Guo  ORCID: https://orcid.org/0000-0002-3283-1111 and Mason, Malcolm D.  ORCID: https://orcid.org/0000-0003-1505-2869
      1999.
      
      HGF/SF influences the interaction between APC, GSK3 beta and beta-catenin, its impact on cell adhesion and in vitro invasion in prostate cancer.
      British Journal of Cancer
      80
      
        (Supp 2)
      
      , p. 36. | 
|   | 
| Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Davies, Eleri-Lloyd and Jiang, Wen Guo  ORCID: https://orcid.org/0000-0002-3283-1111
      1998.
      
      Up-regulation of the expression of hepatocyte growth factor activator (HGFA) in breast cancer.
      British Journal of Cancer
      78
      
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      , p. 150.
      
      10.1038/bjc.1998.457 | 
|   | 
| Jiang, Wen Guo  ORCID: https://orcid.org/0000-0002-3283-1111, Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Bryce, R. P., Horrobin, D. F. and Mansel, Robert Edward  ORCID: https://orcid.org/0000-0002-8051-0726
      1998.
      
      The effects of n-6 polyunsaturated fatty acids on the expression of nm-23 in human cancer cells.
      British Journal of Cancer
      77
      
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      , pp. 731-738.
      
      10.1038/bjc.1998.120 | 
|   | 
| Jiang, W., Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Bryce, R. P., Horrobin, D. F. and Mansel, R. E.
      1998.
      
      The effects of n-6 polyunsaturated fatty acids on the expression of metastasis suppressors in cancer cells.
      Presented at: Fourth International Congress on Essential Fatty Acids and Eicosanoids,
      Edinburgh, UK,
      20-24 July 1997.
      Published in: Riemersma, Rudolph A., Armstrong, Roma, Kelly, Rodney W. and Wilson, Robert eds.
      The Fourth International Congress on Essential Fatty Acids and Eicosanoids : Invited Papers From the Fourth International Congress.
      FOURTH INTERNATIONAL CONGRESS ON ESSENTIAL FATTY ACIDS AND EICOSANOIDS.
      
      
       
      
      Champaign, Ill: 
      Amer Oil Chemists Society Press,
      pp. 303-311. | 
|   | 
| Thomas, D. W., Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Stephens, P. and Jiang, W.
      1998.
      
      Phenotypic variation in HGF production and bioactivity between oral and skin fibroblasts.
      Journal of Dental Research
      77
      
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      10.1177/0022034598077S201 | 
|   | 
| Jiang, Wen Guo  ORCID: https://orcid.org/0000-0002-3283-1111, Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Horrobin, D. F., Bryce, R. P. and Mansel, Robert Edward  ORCID: https://orcid.org/0000-0002-8051-0726
      1998.
      
      Essential fatty acids regulate the expression of tumour suppressor genes in  cancer cells.
      Presented at: Fourth International Congress on Essential Fatty Acids and Eicosanoids,
      Edinburgh, UK,
      20-24 July 1997.
      Published in: Riemersma, Rudolph A., Armstrong, Roma, Kelly, Rodney W. and Wilson, Robert eds.
      Essential fatty acids and eicosanoids: invited papers from the Fourth International Congress.
      
      
      
       
      
      Champaign, Illinois: 
      AOCS Press,
      pp. 303-311. | 
|   | 
| Jiang, Wen Guo  ORCID: https://orcid.org/0000-0002-3283-1111, Singhrao, Sim K., Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Hallett, Maurice Bartlett  ORCID: https://orcid.org/0000-0001-8197-834X, Bryce, Richard B., Horrobin, David F., Puntis, Malcolm C. A. and Mansel, Robert Edward  ORCID: https://orcid.org/0000-0002-8051-0726
      1997.
      
      Regulation of desmosomal cell adhesion in human tumour cells by polyunsaturated fatty acids.
      Clinical and Experimental Metastasis
      15
      
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      , pp. 593-602.
      
      10.1023/A:1018435229087 | 
|   | 
| Jiang, Wen Guo  ORCID: https://orcid.org/0000-0002-3283-1111 and Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702
      1997.
      
      beta-catenin-cell adhesion and beyond (review).
      International Journal of Oncology
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      , pp. 635-641. | 
|   | 
| Davies, Eleri-Lloyd, Cochrane, Richard A., Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Jiang, Wen Guo  ORCID: https://orcid.org/0000-0002-3283-1111, Sweetland, Helen Margaret and Mansel, Robert Edrawd  ORCID: https://orcid.org/0000-0002-8051-0726
      1997.
      
      The role of desmoglein 2 and E-cadherin in the invasion and motility of human breast cancer cells.
      International Journal of Oncology
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      , pp. 415-419. | 
|   | 
| Jiang, Wen Guo  ORCID: https://orcid.org/0000-0002-3283-1111, Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Horrobin, David F., Bryce, Richard P. and Mansel, Robert Edward  ORCID: https://orcid.org/0000-0002-8051-0726
      1997.
      
      Gamma linolenic acid regulates expression of maspin and the motility of cancer cells.
      Biochemical and Biophysical Research Communications
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      , pp. 639-644.
      
      10.1006/bbrc.1997.7154 | 
|   | 
| Jiang, Wen Guo  ORCID: https://orcid.org/0000-0002-3283-1111 and Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702
      1997.
      
      Hepatocyte growth factor/scatter factor, a cytokine playing multiple and converse roles.
      Histology and Histopathology
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      , pp. 537-555. | 
|   | 
| Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702 and Jiang, Wen Guo  ORCID: https://orcid.org/0000-0002-3283-1111
      1997.
      
      Regulation of endothelial CD44 expression and endothelium-tumour cell interactions by hepatocyte growth factor/scatter factor.
      Biochemical and Biophysical Research Communications
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      , pp. 1-5.
      
      10.1006/bbrc.1997.6388 | 
|   | 
| Jiang, Wen Guo  ORCID: https://orcid.org/0000-0002-3283-1111 and Hiscox, Stephen  ORCID: https://orcid.org/0000-0003-0105-2702
      1997.
      
      Expression of E-cadherin, alpha, beta and gamma-catenin in human colorectal cancer.
      Anticancer Research
      17
      
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|   | 
| Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702, Hallett, Maurice Bartlett  ORCID: https://orcid.org/0000-0001-8197-834X, Jiang, Wen Guo  ORCID: https://orcid.org/0000-0002-3283-1111, Puntis, Malcolm C. A. and Nakamura, Toshikazu
      1997.
      
      Expression of the HGF/SF Receptor, c-met, and its ligand in human colorectal cancers.
      Cancer Investigation
      15
      
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      , pp. 513-521.
      
      10.3109/07357909709047592 | 
|   | 
| Jiang, Wen Guo  ORCID: https://orcid.org/0000-0002-3283-1111 and Hiscox, Stephen Edward  ORCID: https://orcid.org/0000-0003-0105-2702
      1996.
      
      Cytokine regulation of ezrin expression in the human colon cancer cell line HT29.
      Anticancer Research
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|   | 

 
							

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