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Rees, Michael, Smith, Chris, Barrett-Lee, Peter ORCID: https://orcid.org/0000-0002-6246-7357 and Hiscox, Steve ORCID: https://orcid.org/0000-0003-0105-2702 2020. PELP-1 regulates adverse responses to endocrine therapy in Estrogen Receptor (ER) positive breast cancer. Oncotarget 11 (51) , pp. 4722-4734. 10.18632/oncotarget.27846 |
Ranganathan, Prathibha, Chakrabarty, Anindita, Hiscox, Stephen ORCID: https://orcid.org/0000-0003-0105-2702, Limaye, Anil Mukund and Vella, Veronica 2020. Editorial: Resistance to endocrine therapies in cancer. Frontiers in Endocrinology 11 , 196. 10.3389/fendo.2020.00196 |
Davison, Zoë, Nicholson, Robert I., Hiscox, Stephen ORCID: https://orcid.org/0000-0003-0105-2702 and Heard, Charles M. ORCID: https://orcid.org/0000-0001-9703-9777 2018. Co-administration of fish oil with signal transduction inhibitors has anti-migration effects in breast cancer cell lines, in vitro. The Open Biochemistry Journal 12 (1) , pp. 130-148. 10.2174/1874091X01812010130 |
Kandil, Sahar ORCID: https://orcid.org/0000-0003-1806-9623, Prencipe, Filippo, Jones, Samuel, Hiscox, Stephen ORCID: https://orcid.org/0000-0003-0105-2702 and Westwell, Andrew D. ORCID: https://orcid.org/0000-0002-5166-9236 2018. The discovery of new and more potent chloropyramine (C4) analogues for the potential treatment of invasive breast cancer. Chemical Biology and Drug Design 91 (1) , pp. 314-321. 10.1111/cbdd.13083 |
Wymant, Jennifer, Hiscox, Stephen ORCID: https://orcid.org/0000-0003-0105-2702, Westwell, Andrew ORCID: https://orcid.org/0000-0002-5166-9236, Urbe, Sylvie, Clague, Michael and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2016. The Role of BCA2 in the endocytic trafficking of EGFR and significance as a prognostic biomarker in cancer. Journal of Cancer 7 (15) , pp. 2388-2407. 10.7150/jca.15055 |
Jones, Samuel, Smith, Christopher, Hiscox, Stephen ORCID: https://orcid.org/0000-0003-0105-2702 and Jiang, Wen G. ORCID: https://orcid.org/0000-0002-3283-1111 2016. Targeting metastasis and cancer stem-like cells in triple negative breast cancer through inhibition of focal adhesion kinase [Poster Abstract]. Presented at: AACR 107th Annual Meeting 2016, New Orleans, LA, USA, 16-20 April 2016. Cancer Research. , vol.76 (S14) p. 4125. 10.1158/1538-7445.am2016-4125 |
Bellerby, Rebecca, Smith, Chris, Kyme, Sue, Gee, Julia ORCID: https://orcid.org/0000-0001-6483-2015, Günthert, Ursula, Green, Andy, Rakha, Emad, Barrett-Lee, Peter and Hiscox, Stephen ORCID: https://orcid.org/0000-0003-0105-2702 2016. Overexpression of specific CD44 isoforms is associated with aggressive cell features in acquired endocrine resistance. Frontiers in Oncology 6 , 145. 10.3389/fonc.2016.00145 |
Gangadhara, Sharath, Smith, Chris, Barrett-Lee, Peter and Hiscox, Stephen ORCID: https://orcid.org/0000-0003-0105-2702 2016. 3D culture of Her2+ breast cancer cells promotes AKT to MAPK switching and a loss of therapeutic response. BMC Cancer 16 (1) , 345. 10.1186/s12885-016-2377-z |
Elseginy, Samia A., Lazaro, Glorianne, Nawwar, Galal A. M., Amin, Kamilia M., Hiscox, Stephen E. ORCID: https://orcid.org/0000-0003-0105-2702 and Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 2015. Computer-aided identification of novel anticancer compounds with a possible dual HER1/HER2 inhibition mechanism. Bioorganic and Medicinal Chemistry Letters 25 (4) , pp. 758-762. 10.1016/j.bmcl.2014.12.095 |
Wiggins, Helen L., Wymant, Jennifer M., Solfa, Francesca, Hiscox, Stephen E. ORCID: https://orcid.org/0000-0003-0105-2702, Taylor, Kathryn M. ORCID: https://orcid.org/0000-0002-9576-9490, Westwell, Andrew D. ORCID: https://orcid.org/0000-0002-5166-9236 and Jones, Arwyn T. ORCID: https://orcid.org/0000-0003-2781-8905 2015. Disulfiram-induced cytotoxicity and endo-lysosomal sequestration of zinc in breast cancer cells. Biochemical Pharmacology 93 (3) , pp. 332-342. 10.1016/j.bcp.2014.12.014 |
Lazaro, Glorianne, Smith, Chris, Goddard, Lindy, Jordan, Nicola Jane, McClelland, Richard Andrew, Barrett-Lee, Peter, Nicholson, Robert Ian and Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702 2013. Targeting focal adhesion kinase in ER+/HER2+ breast cancer improves trastuzumab response. Endocrine Related Cancer 20 (5) , pp. 691-704. 10.1530/ERC-13-0019 |
Hogstrand, Christer, Kille, Peter ORCID: https://orcid.org/0000-0001-6023-5221, Ackland, Margaret Leigh, Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702 and Taylor, Kathryn Mary ORCID: https://orcid.org/0000-0002-9576-9490 2013. A mechanism for epithelial–mesenchymal transition and anoikis resistance in breast cancer triggered by zinc channel ZIP6 and STAT3 (signal transducer and activator of transcription 3). Biochemical Journal 455 (2) , pp. 229-237. 10.1042/BJ20130483 |
Eccles, Suzanne A., Aboagye, Eric O., Ali, Simak, Anderson, Annie S., Armes, Jo, Berditchevski, Fedor, Blaydes, Jeremy P., Brennan, Keith, Brown, Nicola J., Bryant, Helen E., Bundred, Nigel J., Burchell, Joy M., Campbell, Anna M., Carroll, Jason S., Clarke, Robert B., Coles, Charlotte E., Cook, Gary J. R., Cox, Angela, Curtin, Nicola J., Dekker, Lodewijk V., dos Santos Silva, Isabel, Duffy, Stephen W., Easton, Douglas F., Eccles, Diana M., Edwards, Dylan R., Edwards, Joanne, Evans, D. Gareth, Fenlon, Deborah F., Flanagan, James M., Foster, Claire, Gallagher, William M., Garcia-Closas, Montserrat, Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015, Gescher, Andy J., Goh, Vicky, Groves, Ashley M., Harvey, Amanda J., Harvie, Michelle, Hennessy, Bryan T., Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Holen, Ingunn, Howell, Sacha J., Howell, Anthony, Hubbard, Gill, Hulbert-Williams, Nick, Hunter, Myra S., Jasani, Bharat, Jones, Louise J., Key, Timothy J., Kirwan, Cliona C., Kong, Anthony, Kunkler, Ian H., Langdon, Simon P., Leach, Martin O., Mann, David J., Marshall, John F., Martin, Lesley, Martin, Stewart G., Macdougall, Jennifer E., Miles, David W., Miller, William R., Morris, Joanna R., Moss, Sue M., Mullan, Paul, Natrajan, Rachel, O'Connor, James P. B., O'Connor, Rosemary, Palmieri, Carlo, Pharoah, Paul D. P., Rakha, Emad A., Reed, Elizabeth, Robinson, Simon P., Sahai, Erik, Saxton, John M., Schmid, Peter, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Speirs, Valerie, Stein, Robert, Stingl, John, Streuli, Charles H., Tutt, Andrew N. J., Velikova, Galina, Walker, Rosemary A., Watson, Christine J., Williams, Kaye J., Young, Leonie S. and Thompson, Alastair M. 2013. Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer. Breast Cancer Research 15 (5) , R92. 10.1186/bcr3493 |
Gangadhara, Sharath, Barrett-Lee, Peter, Nicholson, Robert and Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702 2012. Pro-metastatic tumor-stroma interactions in breast cancer. Future Oncology 8 (11) , pp. 1427-1442. 10.2217/fon.12.134. |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Baruha, Bedanta, Smith, Chris, Bellerby, Rebecca, Goddard, Lindy, Jordan, Nicola Jane, Poghosyan, Zaruhi ORCID: https://orcid.org/0000-0003-4966-7618, Nicholson, Robert Ian, Barrett-Lee, Peter and Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015 2012. Overexpression of CD44 accompanies acquired tamoxifen resistance in MCF7 cells and augments their sensitivity to the stromal factors, heregulin and hyaluronan. BMC Cancer 12 , 458. 10.1186/1471-2407-12-458 |
Taylor, Kathryn Mary ORCID: https://orcid.org/0000-0002-9576-9490, Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Nicholson, Robert Ian, Hogstrand, Christer and Kille, Peter ORCID: https://orcid.org/0000-0001-6023-5221 2012. Protein kinase CK2 triggers cytosolic zinc signaling pathways by phosphorylation of zinc channel ZIP7. Science Signaling 5 (210) , ra11. 10.1126/scisignal.2002585 |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Barrett-Lee, Peter ORCID: https://orcid.org/0000-0002-6246-7357 and Nicholson, Robert Ian 2011. Therapeutic targeting of tumor–stroma interactions. Expert Opinion on Therapeutic Targets 15 (5) , pp. 609-621. 10.1517/14728222.2011.561201 |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Barnfather, Peter, Hayes, Edward Raymond, Bramble, Pamela, Christensen, James, Nicholson, Robert Ian and Barrett-Lee, Peter 2011. Inhibition of focal adhesion kinase suppresses the adverse phenotype of endocrine-resistant breast cancer cells and improves endocrine response in endocrine-sensitive cells. Breast Cancer Research and Treatment 125 (3) , pp. 659-669. 10.1007/s10549-010-0857-4 |
Davies, Eleri-Lloyd and Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702 2011. New therapeutic approaches in breast cancer. Maturitas 68 (2) , pp. 121-128. 10.1016/j.maturitas.2010.10.012 |
Wadhawan, Anshu, Smith, Chris, Nicholson, Robert Ian, Barrett-Lee, Peter and Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702 2011. Src-mediated regulation of homotypic cell adhesion: implications for cancer progression and opportunities for therapeutic intervention. Cancer Treatment Reviews 37 (3) , pp. 234-241. 10.1016/j.ctrv.2010.08.003 |
Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015, Nicholson, Robert Ian, Barrow, Denise, Dutkowski, Carol Mary, Goddard, Lindy, Jordan, Nicola J., McClelland, Richard Andrew, Knowlden, Janice Mary, Francies, Hayley E., Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702 and Hutcheson, Iain Robert 2011. Antihormone induced compensatory signalling in breast cancer: an adverse event in the development of endocrine resistance. Hormone Molecular Biology and Clinical Investigation 5 (2) , pp. 67-77. 10.1515/HMBCI.2011.009 |
Hayes, Edward Raymond, Nicholson, Robert I. and Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702 2011. Acquired endocrine resistance in breast cancer: implications for tumour metastasis. Frontiers in Bioscience 16 (1) , pp. 838-848. 10.2741/3723 |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Barrett-Lee, Peter, Borley, Annabel Catherine and Nicholson, Robert Ian 2010. Combining Src inhibitors and aromatase inhibitors: A novel strategy for overcoming endocrine resistance and bone loss. European Journal of Cancer 46 (12) , pp. 2187-2195. 10.1016/j.ejca.2010.04.012 |
Weaver, Benjamin P., Zhang, Yuxia, Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Guo, Grace L., Apte, Udayan, Taylor, Kathryn Mary ORCID: https://orcid.org/0000-0002-9576-9490, Sheline, Christian T., Wang, Li and Andrews, Glen K. 2010. Zip4 (Slc39a4) expression is activated in hepatocellular carcinomas and functions to repress apoptosis, enhance cell cycle and increase migration. PLoS ONE 5 (10) , e13158. 10.1371/journal.pone.0013158 |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Barnfather, Peter, Hayes, Edward Raymond, Bramble, P., Christensen, J., Nicholson, Robert Ian and Barrett-Lee, Peter 2009. Inhibition of Focal Adhesion Kinase Suppresses Adverse Features of Endocrine-Resistant Breast Cancer Cells and Improves Endocrine Response in ER plus , Endocrine-Sensitive Cells [Abstract]. Cancer Research 69 (24:S1) , p. 3130. 10.1158/0008-5472.SABCS-09-3130 |
Morgan, Liam David ORCID: https://orcid.org/0000-0002-7571-6025, Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015, Pumford, Sara Louise, Farrow, Lynne, Finlay, Pauline, Robertson, John, Ellis, Ian, Kawakatsu, Hisaaki, Nicholson, Robert Ian and Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702 2009. Elevated Src kinase activity attenuates tamoxifen response in vitro and is associated with poor prognosis clinically. Cancer Biology and Therapy 8 (16) , pp. 1550-1558. 10.4161/cbt.8.16.8954 |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Jordan, Nicola Jane, Smith, Chris, James, M., Morgan, Liam David ORCID: https://orcid.org/0000-0002-7571-6025, Taylor, Kathryn Mary ORCID: https://orcid.org/0000-0002-9576-9490, Green, T. P. and Nicholson, Robert Ian 2009. Dual targeting of Src and ER prevents acquired antihormone resistance in breast cancer cells. Breast Cancer Research and Treatment 115 (1) , pp. 57-67. 10.1007/s10549-008-0058-6 |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Jordan, Nicola Jane, Morgan, Liam David ORCID: https://orcid.org/0000-0002-7571-6025, Smith, Christopher, Goddard, Lindy, Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015 and Nicholson, Robert 2009. Adverse features of acquired antihormone resistance and their targeting. Hiscox, Stephen Edward, Gee, Julia Margaret Wendy and Nicholson, Robert, eds. Therapeutic Resistance to Anti-Hormonal Drugs in Breast Cancer: New Molecular Aspects and their Potential as Targets, London: Springer, pp. 139-160. (10.1007/978-1-4020-8526-0_8) |
Baruah, Bedanta Prakash, Barrett-Lee, Peter, Smith, Chris, Nicholson, Robert Ian and Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702 2009. CD44-Activated HER-2 Signalling in Tamoxifen Resistant Breast Cancer Cells Promotes a Migratory Phenotype. Cancer Research 69 (24) , 811S-811S. |
Baruah, Bedanta Prakash, Smith, Chris, Jordan, Nicola Jane, Nicholson, Robert Ian, Robertson, Jane, Barrett-Lee, Peter and Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702 2009. Overexpression of CD44 in acquired endocrine resistant breast cancer modulates erbB activity and promotes an invasive phenotype. Cancer Research 69 (2) , 811S-811S. |
Nicholson, Robert Ian, Hutcheson, Iain Robert, Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Taylor, Kathryn Mary ORCID: https://orcid.org/0000-0002-9576-9490 and Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015 2009. Experimental endocrine resistance: concepts and strategies. Hiscox, Stephen Edward, Gee, Julia Margaret Wendy and Nicholson, Robert Ian, eds. Therapeutic Resistance to Anti-Hormonal Drugs in Breast Cancer: New Molecular Aspects and their Potential, Dordrecht: Springer, pp. 1-26. (10.1007/978-1-4020-8526-0_1) |
Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015, Stone, Andrew, McClelland, Richard Andrew, Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Hutcheson, Iain Robert, Jordan, Nicola J., Fiegl, Heidi M., Widschwendter, Martin, Shaw, Victoria E., Barrow, Denise and Nicholson, Robert Ian 2009. The dark side of antihormonal action in breast cancer. Hiscox, Stephen Edward, Gee, Julia Margaret Wendy and Nicholson, Robert Ian, eds. Therapeutic Resistance to Anti-Hormonal Drugs in Breast Cancer: New Molecular Aspects and their Potential, Dordrecht: Springer, pp. 63-84. (10.1007/978-1-4020-8526-0_4) |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Jordan, Nicola Jane, Crandon-Lewis, A., Jiang, W., Nicholson, Robert Ian and Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015 2009. Overexpression of L1CAM accompanies acquired endocrine resistance and is associated with the development of an aggressive cell phenotype [Abstract]. Cancer Research 69 (2) , 213S-213S. 10.1158/0008-5472.SABCS-3028 |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Davies, Eleri-Lloyd and Barrett-Lee, Peter 2009. Aromatase inhibitors in breast cancer. Maturitas 63 (4) , pp. 275-279. 10.1016/j.maturitas.2009.05.008 |
Wadhawan, Anshu, Barrett-Lee, Peter, Smith, Chris, Nicholson, Robert Ian and Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702 2009. Src-Dependent Changes in Beta-Catenin Activity Promote a Migratory Phenotype in Endocrine-Resistant Breast Cancer Cells. Cancer Research 69 (24) , 813S. |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702 and Nicholson, Robert Ian 2009. Resistance to hormone therapy in breast cancer. Advances in Breast Cancer 6 (3) , pp. 2-6. |
Taylor, Kathryn Mary ORCID: https://orcid.org/0000-0002-9576-9490, Vichova, Petra, Jordan, Nicola Jane, Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Hendley, Rhiannon and Nicholson, Robert Ian 2008. ZIP7-mediated intracellular zinc transport contributes to aberrant growth factor signaling in antihormone-resistant breast cancer cells. Endocrinology 149 (10) , pp. 4912-4920. 10.1210/en.2008-0351 |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Goddard, Lindy, Jordan, Nicola Jane, Smith, Chris, Harper, Maureen Elaine, Nicholson, Robert Ian and Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015 2008. Overexpression of CD44 in acquired tamoxifen-resistant breast cancer cells augments their migratory response to heregulin beta 1 [Abstract]. Breast Cancer Research 10 (S2) , P34. 10.1186/bcr1918 |
Morgan, Liam David ORCID: https://orcid.org/0000-0002-7571-6025, Nicholson, Robert and Hiscox, Stephen ORCID: https://orcid.org/0000-0003-0105-2702 2008. Src as a therapeutic target in breast cancer. Endocrine‚ Metabolic & Immune Disorders - Drug Targets 8 (4) , pp. 273-278. 10.2174/187153008786848295 |
Borley, Annabel Catherine, Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015, Smith, Chris, Shaw, Victoria, Barrett-Lee, Peter and Nicholson, Robert Ian 2008. Anti-oestrogens but not oestrogen deprivation promote cellular invasion in intercellular adhesion-deficient breast cancer cells. Breast Cancer Research 10 (6) , R103. 10.1186/bcr2206 |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702 and Nicholson, Robert Ian 2008. Src inhibitors in breast cancer therapy. Expert Opinion on Therapeutic Targets 12 (6) , pp. 757-767. 10.1517/14728220802133204 |
Nicholson, Robert Ian, Hutcheson, Iain Robert, Jones, Helen Elizabeth, Taylor, Kathryn Mary ORCID: https://orcid.org/0000-0002-9576-9490, Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702 and Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015 2008. Compensatory signalling induced by anti-hormone and anti-growth factor therapies in breast cancer: a starting point for the development of resistance to targeted therapies. Pasqualini, Jorge R., ed. Breast cancer: prognosis, treatment and prevention. 2nd ed, London: Informa Healthcare, pp. 123-136. |
Borley, A. C., Barrett-Lee, Peter, Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015, Show, V. E., Nicholson, Robert and Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702 2007. Anti-estrogens promote an invasive phenotype in intercellular adhesion deficient breast cancer cells. Breast Cancer Research and Treatment 106 (Supp 1) , S7-S8. |
Hutcheson, Iain Robert, Knowlden, Janice Mary, Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Barrow, Denise, Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015, Robertson, J. F., Ellis, I. O. and Nicholson, Robert Ian 2007. Heregulin beta 1 drives gefitinib-resistant growth and invasion in tamoxifen-resistant MCF-7 breast cancer cells. Breast Cancer Research 9 (4) , R50. 10.1186/bcr1754 |
Khirwadkar, Yamini, Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Jordan, Nicola Jane and Nicholson, Robert Ian 2007. HGF/SF promotes an aggressive phenotype in c-Met-overexpressing fulvestrant-resistant MCF-7 cells - Evidence for MMP-9 and PI3k involvement [Abstract]. Annals of Oncology 18 (S4) , P611. 10.1093/annonc/mdm166 |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Jordan, Nicola Jane, Morgan, Liam David ORCID: https://orcid.org/0000-0002-7571-6025, Green, T. P. and Nicholson, Robert Ian 2007. Src kinase promotes adhesion-independent activation of FAK and enhances cellular migration in tamoxifen-resistant breast cancer cells. Clinical & Experimental Metastasis 24 (3) , pp. 157-167. 10.1007/s10585-007-9065-y |
Nicholson, Robert Ian, Hutcheson, Iain Robert, Jones, H. E., Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Giles, M., Taylor, Kathryn Mary ORCID: https://orcid.org/0000-0002-9576-9490 and Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015 2007. Growth factor signalling in endocrine and anti-growth factor resistant breast cancer. Reviews in Endocrine and Metabolic Disorders 8 (3) , pp. 241-253. 10.1007/s11154-007-9033-5 |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Green, T. P., Smith, Chris, James, M., Jordan, Nicola Jane and Nicholson, Robert Ian 2007. Combination treatment with AZD0530 and tamoxifen prevents acquired antiestrogen resistance in breast cancer cells [Abstract]. Molecular Cancer Therapeutics 6 (Suppl) , 3411S. |
Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015, Shaw, Victoria E., Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, McClelland, Richard Andrew, Rushmere, N. K. and Nicholson, Robert Ian 2006. Deciphering antihormone-induced compensatory mechanisms in breast cancer and their therapeutic implications. Endocrine-Related Cancer 13 (S1) , S77-S88. 10.1677/erc.1.01274 |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Morgan, Liam David ORCID: https://orcid.org/0000-0002-7571-6025, Green, Tim and Nicholson, Robert 2006. Src as a therapeutic target in anti-hormone/anti-growth factor-resistant breast cancer. Endocrine-Related Cancer 13 , S53-S59. 10.1677/erc.1.01297 |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Jordan, Nicola Jane, Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111, Harper, Maureen Elaine, McClelland, Richard, Smith, Chris and Nicholson, Robert 2006. Chronic exposure to fulvestrant promotes overexpression of the c-Met receptor in breast cancer cells: implications for tumour-stroma interactions. Endocrine-Related Cancer 13 (4) , pp. 1085-1099. 10.1677/erc.1.01270 |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Morgan, Liam David ORCID: https://orcid.org/0000-0002-7571-6025, Green, Tim P., Barrow, Denise, Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015 and Nicholson, Robert Ian 2006. Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells. Breast cancer research and treatment 97 (3) , pp. 263-274. 10.1007/s10549-005-9120-9 |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111, Obermeier, Kathrin, Taylor, Kathryn Mary ORCID: https://orcid.org/0000-0002-9576-9490, Morgan, Liam David ORCID: https://orcid.org/0000-0002-7571-6025, Burmi, Rajpal Singh, Barrow, Denise and Nicholson, Robert Ian 2006. Tamoxifen-resistance in MCF7 cells promotes EMT-like behaviour and involves modulation of [beta]-catenin phosphorylation. International journal of cancer 118 (2) , pp. 290-301. 10.1002/ijc.21355 |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Green, T. P. and Nicholson, R. I. 2006. Combination therapy using AZD0530 and tamoxifen prevents antihormone resistance in breast cancer cells. Breast Cancer Research and Treatment 100 (Supp 1) , S246-S246. |
Nicholson, Robert Ian, Hutcheson, Iain Robert, Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Knowlden, Janice Mary, Giles, Martin Gwyn, Barrow, Denise and Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015 2005. Growth factor signalling and resistance to selective oestrogen receptor modulators and pure anti-oestrogens: the use of anti-growth factor therapies to treat or delay endocrine resistance in breast cancer. Endocrine-Related Cancer 12 (S1) , S29-S36. 10.1677/erc.1.00991 |
Nicholson, Robert Ian, Hutcheson, Iain Robert, Britton, David James, Knowlden, Janice Mary, Jones, Helen E., Harper, Maureen Elaine, Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Barrow, Denise and Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015 2005. Growth factor signalling networks in breast cancer and resistance to endocrine agents: new therapeutic strategies. The Journal of Steroid Biochemistry and Molecular Biology 93 (2-5) , pp. 257-262. 10.1016/j.jsbmb.2004.12.006 |
Taylor, Kathryn Mary ORCID: https://orcid.org/0000-0002-9576-9490, Vichova, Petra, Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702 and Nicholson, Robert 2005. Zinc-dependant stimulation of Src, EGFR and IGFR signalling pathways in tamoxifen-resistant breast cancer and the role of zinc transporters. Breast Cancer Research and Treatment 94 (Supp 1) , S162-S162. |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Harper, Maureen Elaine, Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111, McClelland, Richard and Nicholson, Robert 2005. Elevated c-met expression accompanies endocrine resistance in MCF7 breast cancer cells and promotes in vitro cell migration and invasion. Breast Cancer Research and Treatment 94 (Supp 1) , S161-S161. |
Jones, Helen E., Goddard, Lindy, Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015, Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Rubini, M., Barrow, Denise, Knowlden, Janice Mary, Williams, Sophie E., Wakeling, A. E. and Nicholson, Robert Ian 2004. Insulin-like growth factor-1 receptor signalling and acquired resistance to gefitinib (ZD1839; Iressa) in human breast and prostate cancer cells. Endocrine-Related Cancer 11 (4) , pp. 793-814. 10.1677/erc.1.00799 |
Taylor, Kathryn Mary ORCID: https://orcid.org/0000-0002-9576-9490, Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702 and Nicholson, Robert 2004. Zinc transporter LIV-1: a link between cellular development and cancer progression. Trends in Endocrinology and Metabolism 15 (10) , pp. 461-463. |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Morgan, Liam David ORCID: https://orcid.org/0000-0002-7571-6025, Barrow, Denise, Dutkowski, Carol Mary, Wakeling, Alan and Nicholson, Robert Ian 2004. Tamoxifen resistance in breast cancer cells is accompanied by an enhanced motile and invasive phenotype: inhibition by gefitinib ('Iressa', ZD1839). Clinical & Experimental Metastasis 21 (3) , pp. 201-212. 10.1023/B:CLIN.0000037697.76011.1d |
Nicholson, Robert, Hutcheson, Iain Robert, Knowlden, Janice Mary, Jones, Helen E., Harper, Maureen Elaine, Jordan, Nicola Jane, Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Barrow, Denise and Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015 2004. Nonendocrine pathways and endocrine resistance: observations with antiestrogens and signal transduction inhibitors in combination. Clinical Cancer Research 10 (1) , 346s-354s. 10.1158/1078-0432.CCR-031206 |
Nicholson, Robert, Hutcheson, Iain Robert, Knowlden, Janice Mary, Britton, David James, Harper, Maureen Elaine, Jordan, Nicola Jane, Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Barrow, Denise and Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015 2004. Chapter 16: beyond antihormones in the targeted therapy of breast cancer. Ingle, James N. and Dowsett, Mitchell, eds. Endocrine Therapy for Breast Cancer Proceedings of the 2003 Gleneagles Conference, New York: Marcel Dekker, pp. 249-258. |
Nicholson, Robert Ian, Jones, Helen E., Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015, Barrow, Denise, Hiscox, Stephen Eward ORCID: https://orcid.org/0000-0003-0105-2702, Harper, Maureen Elaine, Rubini, M., Guy, S. and Wakeling, A. E. 2003. Insulin-like growth factor-1 receptor signalling and acquired resistance to gefitinib ('Iressa', ZD1839) in MCF-7 human breast cancer cells [Abstract]. Breast Cancer Research and Treatment 82 (S1) , S171. 10.1023/A:1026252325164 |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X, Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Van Den Berg, Carmen Wilma 2002. GPI-anchored GFP signals Ca2+ but is homogeneously distributed on the cell surface. Biochemical and Biophysical Research Communications 293 (2) , pp. 714-721. 10.1016/S0006-291X(02)00280-2 |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702 and Van Den Berg, Carmen Wilma 2001. Characterisation of cell activation through cyt2 and cyt1 tail of MCP. Molecular Immunology 38 (2-3) , pp. 96-97. |
Parr, C., Davies, G., Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Nakamura, T., Matsumoto, K., Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 and Mansel, Robert Edward ORCID: https://orcid.org/0000-0002-8051-0726 2001. Inhibition of HGF/SF-induced cell-matrix adhesion, invasion, migration & paxillin phosphorylation, in prostate cancer by the HGF/SF antagonist, NK4. British Journal of Cancer 85 (Supp 1) , p. 86. 10.1054/bjoc.2001.1918 |
Stead, Paul, Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Robinson, Phil S., Pike, Nicholas B., Sidebottom, Philip J., Roberts, Andrew D., Taylor, Nicholas L., Wright, Amy E., Pomponi, Shirley A. and Langley, David 2000. Eryloside F, a novel penasterol disaccharide possessing potent thrombin receptor antagonist activity. Biorganic and Medicinal Chemistry Letters 10 (7) , pp. 661-664. |
Parr, Christian, Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Nakamura, Toshikazu, Matumoto, Kunio and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 2000. NK4, a new HGF/SF variant, is an antagonist to the influence of HGF/SF on the motility and invasion of colon cancer cells. International Journal of Cancer 85 (4) , pp. 563-570. 10.1002/(SICI)1097-0215(20000215)85:4<563::AID-IJC19>3.0.CO;2-D |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Parr, Christian, Nakamura, Toshikazu, Matsumoto, Kunio, Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 and Mansel, Robert Edward ORCID: https://orcid.org/0000-0002-8051-0726 2000. Inhibition of HGF/SF-induced breast cancer cell motility and invasion by the HGF/SF variant, NK4. British Journal of Cancer 59 (3) , pp. 245-254. 10.1023/A:1006348317841 |
Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111, Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Parr, Christian, Martin, Tracey Amanda ORCID: https://orcid.org/0000-0003-2690-4908, Matsumoto, Kunio, Nakamura, Toshikazu and Mansel, Robert Edward ORCID: https://orcid.org/0000-0002-8051-0726 1999. Antagonistic effect of NK4, a novel hepatocyte growth factor variant, on in vitro angiogenesis of human vascular endothelial cells. Clinical Cancer Research 5 (11) , pp. 3695-3703. |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702 and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 1999. Ezrin regulates cell-cell and cell-matrix adhesion, a possible role with E-cadherin/beta-catenin. Journal of Cell Science 112 (18) , pp. 3081-3090. |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702 and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 1999. Association of the HGF/SF receptor, c-met, with the cell-surface adhesion molecule, E-cadherin, and catenins in human tumor cells. Biochemical and Biophysical Research Communications 261 (2) , pp. 406-411. 10.1006/bbrc.1999.1002 |
Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111, Hiscox, Stephen ORCID: https://orcid.org/0000-0003-0105-2702, Matsumoto, Kunio and Nakamura, Toshikazu 1999. Hepatocyte growth factor/scatter factor, its molecular, cellular and clinical implications in cancer. Critical Reviews in Oncology/Hematology 29 (3) , pp. 209-248. |
Davies, G., Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Llaffafian, I., Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 and Mason, Malcolm D. ORCID: https://orcid.org/0000-0003-1505-2869 1999. HGF/SF influences the interaction between APC, GSK3 beta and beta-catenin, its impact on cell adhesion and in vitro invasion in prostate cancer. British Journal of Cancer 80 (Supp 2) , p. 36. |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Davies, Eleri-Lloyd and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 1998. Up-regulation of the expression of hepatocyte growth factor activator (HGFA) in breast cancer. British Journal of Cancer 78 (2) , p. 150. 10.1038/bjc.1998.457 |
Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111, Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Bryce, R. P., Horrobin, D. F. and Mansel, Robert Edward ORCID: https://orcid.org/0000-0002-8051-0726 1998. The effects of n-6 polyunsaturated fatty acids on the expression of nm-23 in human cancer cells. British Journal of Cancer 77 (5) , pp. 731-738. 10.1038/bjc.1998.120 |
Jiang, W., Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Bryce, R. P., Horrobin, D. F. and Mansel, R. E. 1998. The effects of n-6 polyunsaturated fatty acids on the expression of metastasis suppressors in cancer cells. Presented at: Fourth International Congress on Essential Fatty Acids and Eicosanoids, Edinburgh, UK, 20-24 July 1997. Published in: Riemersma, Rudolph A., Armstrong, Roma, Kelly, Rodney W. and Wilson, Robert eds. The Fourth International Congress on Essential Fatty Acids and Eicosanoids : Invited Papers From the Fourth International Congress. FOURTH INTERNATIONAL CONGRESS ON ESSENTIAL FATTY ACIDS AND EICOSANOIDS. Champaign, Ill: Amer Oil Chemists Society Press, pp. 303-311. |
Thomas, D. W., Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Stephens, P. and Jiang, W. 1998. Phenotypic variation in HGF production and bioactivity between oral and skin fibroblasts. Journal of Dental Research 77 (Supp 2) , p. 767. 10.1177/0022034598077S201 |
Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111, Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Horrobin, D. F., Bryce, R. P. and Mansel, Robert Edward ORCID: https://orcid.org/0000-0002-8051-0726 1998. Essential fatty acids regulate the expression of tumour suppressor genes in cancer cells. Presented at: Fourth International Congress on Essential Fatty Acids and Eicosanoids, Edinburgh, UK, 20-24 July 1997. Published in: Riemersma, Rudolph A., Armstrong, Roma, Kelly, Rodney W. and Wilson, Robert eds. Essential fatty acids and eicosanoids: invited papers from the Fourth International Congress. Champaign, Illinois: AOCS Press, pp. 303-311. |
Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111, Singhrao, Sim K., Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X, Bryce, Richard B., Horrobin, David F., Puntis, Malcolm C. A. and Mansel, Robert Edward ORCID: https://orcid.org/0000-0002-8051-0726 1997. Regulation of desmosomal cell adhesion in human tumour cells by polyunsaturated fatty acids. Clinical and Experimental Metastasis 15 (6) , pp. 593-602. 10.1023/A:1018435229087 |
Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 and Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702 1997. beta-catenin-cell adhesion and beyond (review). International Journal of Oncology 11 (3) , pp. 635-641. |
Davies, Eleri-Lloyd, Cochrane, Richard A., Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111, Sweetland, Helen Margaret and Mansel, Robert Edrawd ORCID: https://orcid.org/0000-0002-8051-0726 1997. The role of desmoglein 2 and E-cadherin in the invasion and motility of human breast cancer cells. International Journal of Oncology 11 (2) , pp. 415-419. |
Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111, Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Horrobin, David F., Bryce, Richard P. and Mansel, Robert Edward ORCID: https://orcid.org/0000-0002-8051-0726 1997. Gamma linolenic acid regulates expression of maspin and the motility of cancer cells. Biochemical and Biophysical Research Communications 237 (3) , pp. 639-644. 10.1006/bbrc.1997.7154 |
Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 and Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702 1997. Hepatocyte growth factor/scatter factor, a cytokine playing multiple and converse roles. Histology and Histopathology 12 (2) , pp. 537-555. |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702 and Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 1997. Regulation of endothelial CD44 expression and endothelium-tumour cell interactions by hepatocyte growth factor/scatter factor. Biochemical and Biophysical Research Communications 233 (1) , pp. 1-5. 10.1006/bbrc.1997.6388 |
Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 and Hiscox, Stephen ORCID: https://orcid.org/0000-0003-0105-2702 1997. Expression of E-cadherin, alpha, beta and gamma-catenin in human colorectal cancer. Anticancer Research 17 , pp. 1349-1354. |
Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X, Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111, Puntis, Malcolm C. A. and Nakamura, Toshikazu 1997. Expression of the HGF/SF Receptor, c-met, and its ligand in human colorectal cancers. Cancer Investigation 15 (6) , pp. 513-521. 10.3109/07357909709047592 |
Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111 and Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702 1996. Cytokine regulation of ezrin expression in the human colon cancer cell line HT29. Anticancer Research 16 (2) , pp. 861-865. |