Gao, Yu, Curtis, Cai, Adamo, Sarah, Biteus, Elsa, Kamal, Habiba, Dager, Lena, Miners, Kelly L., Llewellyn-Lacey, Sian, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Amratia, Pragati, Bentley, Kirsten ORCID: https://orcid.org/0000-0002-6619-2098, Kollnberger, Simon, Wu, Jinghua, Akhirunnesa, Mily, Jones, Samantha, Julin, Per, Lidman, Christer, Stanton, Richard ORCID: https://orcid.org/0000-0002-6799-1182, Goepfert, Paul, Peluso, Michael, Deeks, Steven, Davies, Helen, Aleman, Soo, Buggert, Marcus and Price, David ORCID: https://orcid.org/0000-0001-9416-2737
2025.
Identification of soluble biomarkers that associate with distinct manifestations of long COVID.
Nature Immunology
26
, 692–705.
10.1038/s41590-025-02135-5
|
|
|
Autaa, Gaëlle, Papagno, Laura, Nogimori, Takuto, Boizard-Moracchini, Andrea, Korenkov, Daniil, Roy, Maeva, Suzuki, Koichiro, Masuta, Yuji, White, Eoghann, Llewellyn-Lacey, Sian, Yoshioka, Yasuo, Nicoli, Francesco, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Dechanet-Merville, Julie, Yamamoto, Takuya, Pellegrin, Isabelle and Appay, Victor
2025.
Ageing and inflammation limit the induction of SARS-CoV-2-specific CD8+ T cell responses in severe COVID-19.
JCI Insight
10
(4)
, e180867.
10.1172/jci.insight.180867
|
|
|
Berneman, Zwi N., De Laere, Maxime, Germonpré, Paul, Huizing, Manon T., Willemen, Yannick, Lion, Eva, De Reu, Hans, Van den Bossche, Jolien, Van den Brande, Jan, Specenier, Pol, Altintas, Sevilay, van Dam, Peter A., Cools, Nathalie, Nijs, Griet, Stein, Barbara, Caluwaerts, Kim, Snoeckx, Annemiek, Op de Beeck, Bart, Saevels, Kirsten, Rutsaert, Lynn, Vandenbosch, Irma, Oner, Gizem, Lammens, Martin, Van Damme, Pierre, Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Oka, Yoshihiro, Oji, Yusuke, Sugiyama, Haruo, Couttenye, Marie M., Van de Velde, Ann L., Van Tendeloo, Viggo F., Peeters, Marc, Anguille, Sébastien and Smits, Evelien L.J.M.
2025.
WT1-mRNA dendritic cell vaccination of patients with glioblastoma multiforme, malignant pleural mesothelioma, metastatic breast cancer, and other solid tumors: type 1 T-lymphocyte responses are associated with clinical outcome.
Journal of Hematology and Oncology
18
(1)
, 9.
10.1186/s13045-025-01661-x
|
|
|
White, Eoghann, Papagno, Laura, Samri, Assia, Sugata, Kenji, Hejblum, Boris, Henry, Amy R., Rogan, Daniel C., Darko, Samuel, Recordon-Pinson, Patricia, Dudoit, Yasmine, Llewellyn-Lacey, Sian, Chakrabarti, Lisa A., Buseyne, Florence, Migueles, Stephen A., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Andreola, Marie-Aline, Satou, Yorifumi, Thiebaut, Rodolphe, Katlama, Christine, Autran, Brigitte, Douek, Daniel C. and Appay, Victor
2024.
Clonal succession after prolonged antiretroviral therapy rejuvenates CD8+ T cell responses against HIV-1.
Nature Immunology
25
(9)
, 1555–1564.
10.1038/s41590-024-01931-9
|
|
|
Dallan, Beatrice, Proietto, Davide, De Laurentis, Martina, Gallerani, Eleonora, Martino, Mara, Ghisellini, Sara, Zurlo, Amedeo, Volpato, Stefano, Govoni, Benedetta, Borghesi, Michela, Albanese, Valentina, Appay, Victor, Bonnini, Stefano, Llewellyn-Lacey, Sian, Pacifico, Salvatore, Grumiro, Laura, Brandolini, Martina, Semprini, Simona, Sambri, Vittorio, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Parry, Helen M., Moss, Paul A. H., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Barbieri, Elena, Bernardi, Tatiana, Boni, Michela, Dall?Olio, Linda, De Laurentis, Martina, Fiorini, Caterina, Fiorini, Michele, Govoni, Maurizio, Neri, Margherita, Palma, Fabio, Romagnoni, Franco, Caputo, Antonella, Gavioli, Riccardo and Nicoli, Francesco
2024.
Age differentially impacts adaptive immune responses induced by adenoviral versus mRNA vaccines against COVID-19.
Nature Aging
4
(8)
, 1121–1136.
10.1038/s43587-024-00644-w
|
|
|
Heim, Kathrin, Saga, Sagar, Sogukpinar, Özlem, Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Emmerich, Florian, Kraft, Anke R. M., Cornberg, Markus, Kielbassa, Sophie, Knolle, Percy, Wohlleber, Dirk, Bengsch, Bertram, Boettler, Tobias, Neumann-Haefelin, Christoph, Thimme, Robert and Hofmann, Maike
2024.
Attenuated effector T cells are linked to control of chronic HBV infection.
Nature Immunology
25
(9)
, pp. 1650-1662.
10.1038/s41590-024-01928-4
|
|
|
Simpson, Jennifer, Starke, Carly E., Ortiz, Alexandra M., Ransier, Amy, Darko, Sam, Llewellyn-Lacey, Sian, Fennessey, Christine M., Keele, Brandon F., Douek, Daniel C., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and Brenchley, Jason M.
2024.
Immunotoxin-mediated depletion of Gag-specific CD8+ T cells undermines natural control of SIV.
JCI Insight
9
(14)
10.1172/jci.insight.174168
|
|
|
Cabral-Piccin, Mariela P., Briceño, Olivia, Papagno, Laura, Liouville, Benjamin, White, Eoghann, Perdomo-Celis, Federico, Autaa, Gaëlle, Volant, Stevenn, Llewellyn-Lacey, Sian, Fromentin, Rémi, Chomont, Nicolas, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Sáez-Cirión, Asier, Lambotte, Olivier, Katlama, Christine and Appay, Victor
2024.
CD8+ T cell priming is quantitatively but not qualitatively impaired in people with HIV-1 on antiretroviral therapy.
AIDS
38
(2)
, pp. 161-166.
10.1097/QAD.0000000000003746
|
|
|
Cai, Curtis, Gao, Yu, Adamo, Sarah, Rivera-Ballesteros, Olga, Hansson, Lotta, Österborg, Anders, Bergman, Peter, Sandberg, Johan K., Ljunggren, Hans-Gustaf, Björkström, Niklas K., Strålin, Kristoffer, Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Qin, Chuan, Grifoni, Alba, Weiskopf, Daniela, Wherry, E. John, Sette, Alessandro, Aleman, Soo and Buggert, Marcus
2023.
SARS-CoV-2 vaccination enhances the effector qualities of spike-specific T cells induced by COVID-19.
Science Immunology
8
(90)
10.1126/sciimmunol.adh0687
|
|
|
Winkler, Frances, Hipp, Anna V., Ramirez, Carlos, Martin, Bianca, Villa, Matteo, Neuwirt, Emilia, Gorka, Oliver, Aerssens, Jeroen, Johansson, Susanne E., Rana, Nisha, Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Panning, Marcus, Groß, Olaf, Pearce, Erika L., Hermann, Carl M., Schumann, Kathrin, Hannibal, Luciana, Neumann-Haefelin, Christoph, Boettler, Tobias, Knolle, Percy, Hofmann, Maike, Wohlleber, Dirk, Thimme, Robert and Bengsch, Bertram
2023.
Enolase represents a metabolic checkpoint controlling the differential exhaustion programmes of hepatitis virus-specific CD8 + T cells.
Gut
72
(10)
, pp. 1971-1984.
10.1136/gutjnl-2022-328734
|
|
|
Adamo, Sarah, Gao, Yu, Sekine, Takuya, Mily, Akhirunnesa, Wu, Jinghua, Storgärd, Elisabet, Westergren, Victor, Filén, Finn, Treutiger, Carl-Johan, Sandberg, Johan K., Sällberg, Matti, Bergman, Peter, Llewellyn-Lacey, Sian, Ljunggren, Hans-Gustaf, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Ekström, Anna-Mia, Sette, Alessandro, Grifoni, Alba and Buggert, Marcus
2023.
Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox.
Cell Host & Microbe
31
(6)
, pp. 928-936.
10.1016/j.chom.2023.04.015
|
|
|
Fahad, Ahmed S., Chung, Cheng Yu, López Acevedo, Sheila N., Boyle, Nicoleen, Madan, Bharat, Gutiérrez-González, Matías F., Matus-Nicodemos, Rodrigo, Laflin, Amy D., Ladi, Rukmini R., Zhou, John, Wolfe, Jacy, Llewellyn-Lacey, Sian, Koup, Richard A., Douek, Daniel C., Balfour, Henry H., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and DeKosky, Brandon J.
2023.
Cell activation-based screening of natively paired human T cell receptor repertoires.
Scientific Reports
13
, 8011.
10.1038/s41598-023-31858-4
|
|
|
Cabral-Piccin, Mariela P., Papagno, Laura, Lahaye, Xavier, Perdomo-Celis, Federico, Volant, Stevenn, White, Eoghann, Monceaux, Valérie, Llewellyn-Lacey, Sian, Fromentin, Rémi, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Chomont, Nicolas, Manel, Nicolas, Saez-Cirion, Asier and Appay, Victor
2023.
Primary role of type I interferons for the induction of functionally optimal antigen-specific CD8+ T cells in HIV infection.
EBioMedicine
91
, 104557.
10.1016/j.ebiom.2023.104557
|
|
|
Proietto, Davide, Dallan, Beatrice, Gallerani, Eleonora, Albanese, Valentina, Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Appay, Victor, Pacifico, Salvatore, Caputo, Antonella, Nicoli, Francesco and Gavioli, Riccardo
2023.
Ageing curtails the diversity and functionality of nascent CD8 + T cell responses against SARS-CoV-2.
Vaccines
11
(1)
, 154.
10.3390/vaccines11010154
|
|
|
Fahad, Ahmed S, Chung, Cheng-Yu, Lopez Acevedo, Sheila N, Boyle, Nicoleen, Madan, Bharat, Gutiérrez-González, Matias F, Matus-Nicodemos, Rodrigo, Laflin, Amy D, Ladi, Rukmini R, Zhou, John, Wolfe, Jacy, Llewellyn-Lacey, Sian, Koup, Richard A, Douek, Daniel C, Balfour Jr, Henry H, Price, David A ORCID: https://orcid.org/0000-0001-9416-2737 and DeKosky, Brandon J
2022.
Immortalization and functional screening of natively paired human T cell receptor repertoires.
Protein Engineering, Design & Selection
35
, gzab034.
10.1093/protein/gzab034
|
|
|
Nicoli, Francesco, Cabral-Piccin, Mariela P., Papagno, Laura, Gallerani, Eleonora, Fusaro, Mathieu, Folcher, Victor, Dubois, Marion, Clave, Emmanuel, Vallet, Hélène, Frere, Justin J., Gostick, Emma, Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Toubert, Antoine, Dupré, Loïc, Boddaert, Jacques, Caputo, Antonella, Gavioli, Riccardo and Appay, Victor
2022.
Altered basal lipid metabolism underlies the functional impairment of naive CD8+ T cells in elderly humans.
The Journal of Immunology
208
(3)
, 562–570.
10.4049/jimmunol.2100194
|
|
Niessl, Julia, Sekine, Takuya, Lange, Joshua, Konya, Viktoria, Forkel, Marianne, Maric, Jovana, Rao, Anna, Mazzurana, Luca, Kokkinou, Efthymia, Weigel, Whitney, Llewellyn-Lacey, Sian, Hodcroft, Emma B., Karlsson, Annika C., Fehrm, Johan, Sundman, Joar, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Mjösberg, Jenny, Friberg, Danielle and Buggert, Marcus
2021.
Identification of resident memory CD8+ T cells with functional specificity for SARS-CoV-2 in unexposed oropharyngeal lymphoid tissue.
Science Immunology
6
(64)
, eabk0894.
10.1126/sciimmunol.abk0894
|
|
|
Man, Stephen ORCID: https://orcid.org/0000-0001-9103-1686, Redman, James E. ORCID: https://orcid.org/0000-0001-5492-2869, Cross, Deborah L., Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Can, Ilona, Davies, Bethan, Hashimdeen, Shaikh Shimaz, Reid, Reiss, Llewellyn-Lacey, Sian, Miners, Kelly L., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Lissina, Anya, Brown, Paul E., Wooldridge, Linda, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369
2021.
Synthetic peptides with inadvertent chemical modifications can activate potentially autoreactive T cells.
The Journal of Immunology
207
(4)
, pp. 1009-1017.
10.4049/jimmunol.2000756
|
|
Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Knezevic, Lea, Dockree, Tamsin, McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly L., Llewellyn-Lacey, Sian, Rubina, Anzelika, Francis, Ore, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Bridgeman, John S., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, van den Berg, Hugo A. and Wooldridge, Linda
2021.
CD8 coreceptor-mediated focusing can reorder the agonist hierarchy of peptide ligands recognized via the T cell receptor.
Proceedings of the National Academy of Sciences
118
(29)
, e2019639118.
10.1073/pnas.2019639118
|
|
|
Heim, Kathrin, Binder, Benedikt, Sagar, Wieland, Dominik, Hensel, Nina, Llewellyn-Lacey, Sian, Gostick, Emma, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Emmerich, Florian, Vingerhoet, Hildegard, Kraft, Anke R M, Cornberg, Markus, Boettler, Tobias, Neumann-Haefelin, Christoph, Zehn, Dietmar, Bengsch, Bertram, Hofmann, Maike and Thimme, Robert
2021.
TOX defines the degree of CD8+ T cell dysfunction in distinct phases of chronic HBV infection.
Gut
70
, pp. 1550-1560.
10.1136/gutjnl-2020-322404
|
|
|
Nicoli, Francesco, Pacifico, Salvatore, Gallerani, Eleonora, Marzola, Erika, Albanese, Valentina, Finessi, Valentina, Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Appay, Victor, Marconi, Peggy, Guerrini, Remo, Caputo, Antonella and Gavioli, Riccardo
2021.
Use of a novel peptide welding technology platform for the development of B- and T-Cell epitope-based vaccines.
Vaccines
9
(5)
, 526.
10.3390/vaccines9050526
|
|
|
Hensel, Nina, Gu, Zuguang, Sagar, Wieland, Dominik, Jechow, Katharina, Kemming, Janine, Llewellyn-Lacey, Sian, Gostick, Emma, Sogukpinar, Oezlem, Emmerich, Florian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Bengsch, Bertram, Boettler, Tobias, Neumann-Haefelin, Christoph, Eils, Roland, Conrad, Christian, Bartenschlager, Ralf, Grün, Dominic, Ishaque, Naveed, Thimme, Robert and Hofmann, Maike
2021.
Memory-like HCV-specific CD8+ T cells retain a molecular scar after cure of chronic HCV infection.
Nature Immunology
22
(2)
, 229–239.
10.1038/s41590-020-00817-w
|
|
Schulien, Isabel, Kemming, Janine, Oberhardt, Valerie, Wild, Katharina, Seidel, Lea M., Killmer, Saskia, Sagar, Daul, Franziska, Salvat Lago, Marilyn, Decker, Annegrit, Luxenburger, Hendrik, Binder, Benedikt, Bettinger, Dominik, Sogukpinar, Oezlem, Rieg, Siegbert, Panning, Marcus, Huzly, Daniela, Schwemmle, Martin, Kochs, Georg, Waller, Cornelius F., Nieters, Alexandra, Duerschmied, Daniel, Emmerich, Florian, Mei, Henrik E., Schulz, Axel Ronald, Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Boettler, Tobias, Bengsch, Bertram, Thimme, Robert, Hofmann, Maike and Neumann-Haefelin, Christoph
2021.
Characterization of pre-existing and induced SARS-CoV-2-specific CD8+ T cells.
Nature Medicine
27
(1)
10.1038/s41591-020-01143-2
|
|
Galletti, Giovanni, De Simone, Gabriele, Mazza, Emilia M.C., Puccio, Simone, Mezzanotte, Claudia, Bi, Timothy M., Davydov, Alexey N., Metsger, Maria, Scamardella, Eloise, Alvisi, Giorgia, Paoli, Federica De, Zanon, Veronica, Scarpa, Alice, Camisa, Barbara, Colombo, Federico S., Anselmo, Achile, Peano, Clelia, Polletti, Sara, Mavilio, Domenico, Gattinoni, Luca, Boi, Shannon K., Youngblood, Benjamin A., Jones, Rhiannon E., Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467, Gostick, Emma, Llewellyn-Lacey, Sian, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Chudakov, Dmitriy M., Newell, Evan W., Casucci, Monica and Lugli, Enrico
2020.
Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans.
Nature Immunology
21
, pp. 1552-1562.
10.1038/s41590-020-0791-5
|
|
|
Buggert, Marcus, Vella, Laura A., Nguyen, Son, Wu, Vincent H., Chen, Zeyu, Sekine, Takuya, Perez-Potti, André, Maldini, Colby R., Manne, Sasikanth, Darko, Samuel, Ransier, Amy, Kuri-Cervantes, Leticia, Japp, Alberto Sada, Brody, Irene Bukh, Ivarsson, Martin A., Gorin, Jean-Baptiste, Rivera-Ballesteros, Olga, Hertwig, Laura, Antel, Jack P., Johnson, Matthew E., Okoye, Afam, Picker, Louis, Vahedi, Golnaz, Sparrelid, Ernesto, Llewellyn-Lacey, Sian, Gostick, Emma, Sandberg, Johan K., Björkström, Niklas, Bar-Or, Amit, Dori, Yoav, Naji, Ali, Canaday, David H., Laufer, Terri M., Wells, Andrew D., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Frank, Ian, Douek, Daniel C., Wherry, E. John, Itkin, Maxim G. and Betts, Michael R.
2020.
The identity of human tissue-emigrant CD8+ T cells.
Cell
183
(7)
, pp. 1946-1961.
10.1016/j.cell.2020.11.019
|
|
|
Weinfurter, Jason T., Graham, Michael E., Ericsen, Adam J., Matschke, Lea M., Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Wiseman, Roger W. and Reynolds, Matthew R.
2020.
Identifying a minor histocompatibility antigen in mauritian cynomolgus macaques encoded by APOBEC3C.
Frontiers in Immunology
11
, 586251.
10.3389/fimmu.2020.586251
|
|
|
Sekine, Takuya, Perez-Potti, André, Rivera-Ballesteros, Olga, Strålin, Kristoffer, Gorin, Jean-Baptiste, Olsson, Annika, Llewellyn-Lacey, Sian, Kamal, Habiba, Bogdanovic, Gordana, Muschiol, Sandra, Wullimann, David J., Kammann, Tobias, Emgård, Johanna, Parrot, Tiphaine, Folkesson, Elin, Rooyackers, Olav, Eriksson, Lars I., Henter, Jan-Inge, Sönnerborg, Anders, Allander, Tobias, Albert, Jan, Nielsen, Morten, Klingström, Jonas, Gredmark-Russ, Sara, Björkström, Niklas K., Sandberg, Johan K., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Ljunggren, Hans-Gustaf, Aleman, Soo, Buggert, Marcus, Akber, Mira, Berglin, Lena, Bergsten, Helena, Brighenti, Susanna, Brownlie, Demi, Butrym, Marta, Chambers, Benedict, Chen, Puran, Jeannin, Martin Cornillet, Grip, Jonathan, Gomez, Angelica Cuapio, Dillner, Lena, Lozano, Isabel Diaz, Dzidic, Majda, Tullberg, Malin Flodström, Färnert, Anna, Glans, Hedvig, Haroun-Izquierdo, Alvaro, Henriksson, Elizabeth, Hertwig, Laura, Kalsum, Sadaf, Kokkinou, Efthymia, Kvedaraite, Egle, Loreti, Marco, Lourda, Magalini, Maleki, Kimia, Malmberg, Karl-Johan, Marquardt, Nicole, Maucourant, Christopher, Michaelsson, Jakob, Mjösberg, Jenny, Moll, Kirsten, Muva, Jagadees, Mårtensson, Johan, Nauclér, Pontus, Norrby-Teglund, Anna, Medina, Laura Palma, Persson, Björn, Radler, Lena, Ringqvist, Emma, Sandberg, John Tyler, Sohlberg, Ebba, Soini, Tea, Svensson, Mattias, Tynell, Janne, Varnaite, Renata, Kries, Andreas Von and Unge, Christian
2020.
Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19.
Cell
183
(1)
, pp. 158-168.
10.1016/j.cell.2020.08.017
|
|
|
Passaes, Caroline, Millet, Antoine, Madelain, Vincent, Monceaux, Valérie, David, Annie, Versmisse, Pierre, Sylla, Naya, Gostick, Emma, Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Blancher, Antoine, Dereuddre-Bosquet, Nathalie, Desjardins, Delphine, Pancino, Gianfranco, Le Grand, Roger, Lambotte, Olivier, Müller-Trutwin, Michaela, Rouzioux, Christine, Guedj, Jérémie, Avettand-Fenoel, Véronique, Vaslin, Bruno and Sáez-Cirión, Asier
2020.
Optimal maturation of the SIV-Specific CD8+ T cell response after primary infection is associated with natural control of SIV: ANRS SIC study.
Cell Reports
32
(12)
, 108174.
10.1016/j.celrep.2020.108174
|
|
|
Sekine, Takuya, Perez-Potti, André, Nguyen, Son, Gorin, Jean-Baptiste, Wu, Vincent H., Gostick, Emma, Llewellyn-Lacey, Sian, Hammer, Quirin, Falck-Jones, Sara, Vangeti, Sindhu, Yu, Meng, Smed-Sörensen, Anna, Gaballa, Ahmed, Uhlin, Michael, Sandberg, Johan K., Brander, Christian, Nowak, Piotr, Goepfert, Paul A., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Betts, Michael R. and Buggert, Marcus
2020.
TOX is expressed by exhausted and polyfunctional human effector memory CD8+ T cells.
Science Immunology
5
(49)
, eaba7918.
10.1126/sciimmunol.aba7918
|
|
|
Pearson, Frances E., Tullett, Kirsteen M., Leal-Rojas, Ingrid M., Haigh, Oscar L., Masterman, Kelly-Anne, Walpole, Carina, Bridgeman, John S., McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly, Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Tunger, Antje, Schmitz, Marc, Miles, John J, Lahoud, Mireille H and Radford, Kristen J
2020.
Human CLEC9A antibodies deliver Wilms' tumor 1 (WT1) antigen to CD141+ dendritic cells to activate naïve and memory WT1‐specific CD8+ T cells.
Clinical and Translational Immunology
9
10.1002/cti2.1141
|
|
|
Tauber, C, Schultheiss, M, De Luca, R, Buettner, N, Llewellyn-Lacey, S, Emmerich, F, Zehe, S, Price, D A ORCID: https://orcid.org/0000-0001-9416-2737, Neumann-Haefelin, C, Schmitt-Graeff, A, Hoffman, M and Thimme, R
2019.
Inefficient induction of circulating TAA-specific CD8+ T-cell responses in hepatocellular carcinoma.
Oncotarget
10
(50)
, pp. 5194-5206.
10.18632/oncotarget.27146
|
|
|
Schuch, Anita, Salimi Alizei, Elahe, Heim, Kathrin, Wieland, Dominik, Kiraithe, Michael Muthamia, Kemming, Janine, Llewellyn-Lacey, Sian, Sogukpinar, Özlem, Ni, Yi, Urban, Stephan, Zimmermann, Peter, Nassal, Michael, Emmerich, Florian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Bengsch, Bertram, Luxenburger, Hendrik, Neumann-Haefelin, Christoph, Hofmann, Maike and Thimme, Robert
2019.
Phenotypic and functional differences of HBV core-specific versus HBV polymerase-specific CD8+ T cells in chronically HBV-infected patients with low viral load.
Gut
68
, pp. 905-915.
10.1136/gutjnl-2018-316641
|
|
|
McLaren, James ORCID: https://orcid.org/0000-0002-7021-5934, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Marsden, Morgan, Miners, Kelly L., Llewellyn-Lacey, Sian, Grant, Emma J., Rubina, Anzelika, Gimeno Brias, Silvia, Gostick, Emma, Stacey, Maria A., Orr, Selinda J., Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337
2019.
IL-33 augments virus-specific memory T Cell inflation and potentiates the efficacy of an attenuated cytomegalovirus-based vaccinea.
Journal of Immunology
202
(3)
, pp. 943-955.
10.4049/jimmunol.1701757
|
|
|
Martin, Maureen P., Naranbhai, Vivek, Shea, Patrick R., Qi, Ying, Ramsuran, Veron, Vince, Nicolas, Gao, Xiaojiang, Thomas, Rasmi, Brumme, Zabrina L., Carlson, Jonathan M., Wolinsky, Steven M., Goedert, James J., Walker, Bruce D., Segal, Florencia P., Deeks, Steven G., Haas, David W., Migueles, Stephen A., Connors, Mark, Michael, Nelson, Fellay, Jacques, Gostick, Emma, Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Lafont, Bernard A., Pymm, Phillip, Saunders, Philippa M., Widjaja, Jacqueline, Wong, Shu Cheng, Vivian, Julian P., Rossjohn, Jamie ORCID: https://orcid.org/0000-0002-2020-7522, Brooks, Andrew G. and Carrington, Mary
2018.
Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1.
Journal of Clinical Investigation
128
(5)
, p. 1903.
10.1172/JCI98463
|
|
|
Lissina, Anna, McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934, Ilander, Mette, Andersson, Emma I., Lewis, Catherine S., Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Herman, Andrew, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Llewellyn-Lacey, Sian, Miners, Kelly L., Gostick, Emma, Melenhorst, J. Joseph, Barrett, A. John, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Mustjoki, Satu and Wooldridge, Linda
2018.
Divergent roles for antigenic drive in the aetiology of primary versus dasatinib-associated CD8+ TCR-Vβ+ expansions.
Scientific Reports
8
(1)
, 2534.
10.1038/s41598-017-18062-x
|
|
|
Dockree, Tamsin, Holland, Christopher J., Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, McLaren, James Edward ORCID: https://orcid.org/0000-0002-7021-5934, Van Den Berg, Hugo A., Gostick, Emma, Llewellyn-Lacey, Sian, Man, Stephen Tzekwung ORCID: https://orcid.org/0000-0001-9103-1686, Bailey, Mick, Burrows, Scott, Price, David ORCID: https://orcid.org/0000-0001-9416-2737 and Wooldridge, Linda
2017.
CD8+ T-cell specificity is compromised at a defined MHCI/CD8 affinity threshold.
Immunology and Cell Biology
95
(1)
, pp. 68-76.
10.1038/icb.2016.85
|
|
|
Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Pearson, James ORCID: https://orcid.org/0000-0002-2867-2269, Gras, Stephanie, Van den berg, Hugo, Lissina, Anya, Llewellyn-Lacey, Sian, Willis, Mark ORCID: https://orcid.org/0000-0003-3024-6063, Dockree, Tamsin, McLaren, James ORCID: https://orcid.org/0000-0002-7021-5934, Ekeruche-Makinde, Julia, Gostick, Emma, Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909, Burrows, Scott, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Peakman, Mark, Skowera, Ania and Wooldridge, Linda
2016.
Targeted suppression of autoreactive CD8+ T-cell activation using blocking anti-CD8 antibodies.
Scientific Reports
6
, 35332.
10.1038/srep35332
|
|
|
Szomolay, Barbara ORCID: https://orcid.org/0000-0002-5375-5533, Liu, Jie, Brown, Paul E., Miles, John J., Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Llewellyn-Lacey, Sian, Dolton, Garry, Ekeruche-Makinde, Julia, Lissina, Anya, Schauenburg, Andrea J., Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Burrows, Scott R., Roederer, Mario, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Wooldridge, Linda and van den Berg, Hugo A.
2016.
Identification of human viral protein-derived ligands recognized by individual MHCI-restricted T-cell receptors.
Immunology and Cell Biology
94
(6)
, pp. 573-582.
10.1038/icb.2016.12
|
|
|
van den Berg, Hugo A., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly, Laugel, Bruno, Llewellyn-Lacey, Sian, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Gostick, Emma, Wooldridge, Linda, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Bridgeman, John S. and Price, David ORCID: https://orcid.org/0000-0001-9416-2737
2013.
Cellular-level versus receptor-level response threshold hierarchies in T-cell activation.
Frontiers in Immunology
4
, 250.
10.3389/fimmu.2013.00250
|
|
|
Eukeruche-Makinde, Julia, Miles, John J., Van Den Berg, Hugo A., Skowera, Ania, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Dolton, Garry Michael, Schauenburg, Andrea, Tan, Mai Ping, Pentier, Johanne, Llewellyn-Lacey, Sian, Miles, Kim M., Bulek, Anna, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Dockree, Tamsin, Trimby, Andrew R., Bailey, Mick, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Rossjohn, Jamie ORCID: https://orcid.org/0000-0002-2020-7522, Peakman, Mark, Burrows, Scott, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 and Wooldridge, Linda
2013.
Peptide length determines the outcome of TCR/peptide-MHCI engagement.
Blood -New York-
121
(7)
, pp. 1112-1123.
10.1182/blood-2012-06-437202
|
|
Ekeruche, Julia, Miles, John James, van den Berg, Hugo A., Skowera, Ania, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Dolton, Garry Michael, Schauenburg, Andrea J. A., Tan, Mai Ping, Pentier, Johanne, Llewellyn-Lacey, Sian, Miles, Kim Michelle, Bulek, Anna Marta, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Williams, Tamsin, Trimby, Andrew R., Bailey, Mick, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Rossjohn, Jamie ORCID: https://orcid.org/0000-0002-2020-7522, Peakman, Mark, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Burrows, Scott R., Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 and Wooldridge, Linda
2013.
Peptide length determines the outcome of TCR/peptide-MHCI engagement.
Blood
121
(7)
, pp. 1112-1123.
10.1182/blood-2012-06-437202
|
|
Wooldridge, Linda, Ekeruche, Julia, van den Berg, Hugo A., Skowera, Anna, Miles, John James, Tan, Mai Ping, Dolton, Garry Michael, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Llewellyn-Lacey, Sian, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Peakman, Mark and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135
2012.
A single autoimmune T cell receptor recognizes more than a million different peptides.
Journal of Biological Chemistry
287
(2)
, pp. 1168-1177.
10.1074/jbc.M111.289488
|
|
|
Chong, Lee Kien, Aicheler, Rebecca, Llewellyn-Lacey, Sian, Tomasec, Peter, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 and Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964
2008.
Proliferation and interleukin 5 production by CD8hiCD57+ T cells.
European Journal of Immunology
38
(4)
, pp. 995-1000.
10.1002/eji.200737687
|
|
Wilkinson, Gavin William Grahame ORCID: https://orcid.org/0000-0002-5623-0126, Tomasec, Peter, Stanton, Richard James ORCID: https://orcid.org/0000-0002-6799-1182, Armstrong, Melanie, Prod'homme, Virginie ORCID: https://orcid.org/0000-0002-9664-4710, Aicheler, Rebecca, McSharry, Brian P., Rickards, Carole R., Cochrane, Daniel, Llewellyn-Lacey, Sian, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Griffin, Cora A. and Davison, Andrew J.
2008.
Modulation of natural killer cells by human cytomegalovirus.
Journal of Clinical Virology
41
(3)
, pp. 206-212.
10.1016/j.jcv.2007.10.027
|
|
Tomasec, Peter, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Davison, Andrew J., Vojtesek, Borivoj, Armstrong, Melanie, Griffin, Cora, McSharry, Brian Patrick, Morris, Rebecca J., Llewellyn-Lacey, Sian, Rickards, Carole Ruth, Nomoto, Akio, Sinzger, Christian and Wilkinson, Gavin William Grahame ORCID: https://orcid.org/0000-0002-5623-0126
2005.
Downregulation of natural killer cell-activating ligand CD155 by human cytomegalovirus UL141.
Nature Immunology
6
(2)
, pp. 181-188.
10.1038/ni1156
|
|



Up a level