White, Eoghann, Papagno, Laura, Samri, Assia, Sugata, Kenji, Hejblum, Boris, Henry, Amy R., Rogan, Daniel C., Darko, Samuel, Recordon-Pinson, Patricia, Dudoit, Yasmine, Llewellyn-Lacey, Sian, Chakrabarti, Lisa A., Buseyne, Florence, Migueles, Stephen A., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Andreola, Marie-Aline, Satou, Yorifumi, Thiebaut, Rodolphe, Katlama, Christine, Autran, Brigitte, Douek, Daniel C. and Appay, Victor
2024.
Clonal succession after prolonged antiretroviral therapy rejuvenates CD8+ T cell responses against HIV-1.
Nature Immunology
25
(9)
, 1555–1564.
10.1038/s41590-024-01931-9
Item availability restricted. |
Dallan, Beatrice, Proietto, Davide, De Laurentis, Martina, Gallerani, Eleonora, Martino, Mara, Ghisellini, Sara, Zurlo, Amedeo, Volpato, Stefano, Govoni, Benedetta, Borghesi, Michela, Albanese, Valentina, Appay, Victor, Bonnini, Stefano, Llewellyn-Lacey, Sian, Pacifico, Salvatore, Grumiro, Laura, Brandolini, Martina, Semprini, Simona, Sambri, Vittorio, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Parry, Helen M., Moss, Paul A. H., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Barbieri, Elena, Bernardi, Tatiana, Boni, Michela, Dall?Olio, Linda, De Laurentis, Martina, Fiorini, Caterina, Fiorini, Michele, Govoni, Maurizio, Neri, Margherita, Palma, Fabio, Romagnoni, Franco, Caputo, Antonella, Gavioli, Riccardo and Nicoli, Francesco
2024.
Age differentially impacts adaptive immune responses induced by adenoviral versus mRNA vaccines against COVID-19.
Nature Aging
4
(8)
, 1121–1136.
10.1038/s43587-024-00644-w
Item availability restricted. |
Heim, Kathrin, Saga, Sagar, Sogukpinar, Özlem, Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Emmerich, Florian, Kraft, Anke R. M., Cornberg, Markus, Kielbassa, Sophie, Knolle, Percy, Wohlleber, Dirk, Bengsch, Bertram, Boettler, Tobias, Neumann-Haefelin, Christoph, Thimme, Robert and Hofmann, Maike 2024. Attenuated effector T cells are linked to control of chronic HBV infection. Nature Immunology 25 (9) , pp. 1650-1662. 10.1038/s41590-024-01928-4 |
Simpson, Jennifer, Starke, Carly E., Ortiz, Alexandra M., Ransier, Amy, Darko, Sam, Llewellyn-Lacey, Sian, Fennessey, Christine M., Keele, Brandon F., Douek, Daniel C., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and Brenchley, Jason M. 2024. Immunotoxin-mediated depletion of Gag-specific CD8+ T cells undermines natural control of SIV. JCI Insight 9 (14) 10.1172/jci.insight.174168 |
Cabral-Piccin, Mariela P., Briceño, Olivia, Papagno, Laura, Liouville, Benjamin, White, Eoghann, Perdomo-Celis, Federico, Autaa, Gaëlle, Volant, Stevenn, Llewellyn-Lacey, Sian, Fromentin, Rémi, Chomont, Nicolas, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Sáez-Cirión, Asier, Lambotte, Olivier, Katlama, Christine and Appay, Victor 2024. CD8+ T cell priming is quantitatively but not qualitatively impaired in people with HIV-1 on antiretroviral therapy. AIDS 38 (2) , pp. 161-166. 10.1097/QAD.0000000000003746 |
Cai, Curtis, Gao, Yu, Adamo, Sarah, Rivera-Ballesteros, Olga, Hansson, Lotta, Österborg, Anders, Bergman, Peter, Sandberg, Johan K., Ljunggren, Hans-Gustaf, Björkström, Niklas K., Strålin, Kristoffer, Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Qin, Chuan, Grifoni, Alba, Weiskopf, Daniela, Wherry, E. John, Sette, Alessandro, Aleman, Soo and Buggert, Marcus 2023. SARS-CoV-2 vaccination enhances the effector qualities of spike-specific T cells induced by COVID-19. Science Immunology 8 (90) 10.1126/sciimmunol.adh0687 |
Winkler, Frances, Hipp, Anna V., Ramirez, Carlos, Martin, Bianca, Villa, Matteo, Neuwirt, Emilia, Gorka, Oliver, Aerssens, Jeroen, Johansson, Susanne E., Rana, Nisha, Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Panning, Marcus, Groß, Olaf, Pearce, Erika L., Hermann, Carl M., Schumann, Kathrin, Hannibal, Luciana, Neumann-Haefelin, Christoph, Boettler, Tobias, Knolle, Percy, Hofmann, Maike, Wohlleber, Dirk, Thimme, Robert and Bengsch, Bertram 2023. Enolase represents a metabolic checkpoint controlling the differential exhaustion programmes of hepatitis virus-specific CD8 + T cells. Gut 72 (10) , pp. 1971-1984. 10.1136/gutjnl-2022-328734 |
Adamo, Sarah, Gao, Yu, Sekine, Takuya, Mily, Akhirunnesa, Wu, Jinghua, Storgärd, Elisabet, Westergren, Victor, Filén, Finn, Treutiger, Carl-Johan, Sandberg, Johan K., Sällberg, Matti, Bergman, Peter, Llewellyn-Lacey, Sian, Ljunggren, Hans-Gustaf, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Ekström, Anna-Mia, Sette, Alessandro, Grifoni, Alba and Buggert, Marcus 2023. Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox. Cell Host & Microbe 31 (6) , pp. 928-936. 10.1016/j.chom.2023.04.015 |
Fahad, Ahmed S., Chung, Cheng Yu, López Acevedo, Sheila N., Boyle, Nicoleen, Madan, Bharat, Gutiérrez-González, Matías F., Matus-Nicodemos, Rodrigo, Laflin, Amy D., Ladi, Rukmini R., Zhou, John, Wolfe, Jacy, Llewellyn-Lacey, Sian, Koup, Richard A., Douek, Daniel C., Balfour, Henry H., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and DeKosky, Brandon J. 2023. Cell activation-based screening of natively paired human T cell receptor repertoires. Scientific Reports 13 , 8011. 10.1038/s41598-023-31858-4 |
Cabral-Piccin, Mariela P., Papagno, Laura, Lahaye, Xavier, Perdomo-Celis, Federico, Volant, Stevenn, White, Eoghann, Monceaux, Valérie, Llewellyn-Lacey, Sian, Fromentin, Rémi, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Chomont, Nicolas, Manel, Nicolas, Saez-Cirion, Asier and Appay, Victor 2023. Primary role of type I interferons for the induction of functionally optimal antigen-specific CD8+ T cells in HIV infection. EBioMedicine 91 , 104557. 10.1016/j.ebiom.2023.104557 |
Proietto, Davide, Dallan, Beatrice, Gallerani, Eleonora, Albanese, Valentina, Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Appay, Victor, Pacifico, Salvatore, Caputo, Antonella, Nicoli, Francesco and Gavioli, Riccardo 2023. Ageing curtails the diversity and functionality of nascent CD8 + T cell responses against SARS-CoV-2. Vaccines 11 (1) , 154. 10.3390/vaccines11010154 |
Fahad, Ahmed S, Chung, Cheng-Yu, Lopez Acevedo, Sheila N, Boyle, Nicoleen, Madan, Bharat, Gutiérrez-González, Matias F, Matus-Nicodemos, Rodrigo, Laflin, Amy D, Ladi, Rukmini R, Zhou, John, Wolfe, Jacy, Llewellyn-Lacey, Sian, Koup, Richard A, Douek, Daniel C, Balfour Jr, Henry H, Price, David A ORCID: https://orcid.org/0000-0001-9416-2737 and DeKosky, Brandon J 2022. Immortalization and functional screening of natively paired human T cell receptor repertoires. Protein Engineering, Design & Selection 35 , gzab034. 10.1093/protein/gzab034 |
Nicoli, Francesco, Cabral-Piccin, Mariela P., Papagno, Laura, Gallerani, Eleonora, Fusaro, Mathieu, Folcher, Victor, Dubois, Marion, Clave, Emmanuel, Vallet, Hélène, Frere, Justin J., Gostick, Emma, Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Toubert, Antoine, Dupré, Loïc, Boddaert, Jacques, Caputo, Antonella, Gavioli, Riccardo and Appay, Victor 2022. Altered basal lipid metabolism underlies the functional impairment of naive CD8+ T cells in elderly humans. The Journal of Immunology 208 (3) , 562–570. 10.4049/jimmunol.2100194 |
Niessl, Julia, Sekine, Takuya, Lange, Joshua, Konya, Viktoria, Forkel, Marianne, Maric, Jovana, Rao, Anna, Mazzurana, Luca, Kokkinou, Efthymia, Weigel, Whitney, Llewellyn-Lacey, Sian, Hodcroft, Emma B., Karlsson, Annika C., Fehrm, Johan, Sundman, Joar, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Mjösberg, Jenny, Friberg, Danielle and Buggert, Marcus 2021. Identification of resident memory CD8+ T cells with functional specificity for SARS-CoV-2 in unexposed oropharyngeal lymphoid tissue. Science Immunology 6 (64) , eabk0894. 10.1126/sciimmunol.abk0894 |
Man, Stephen ORCID: https://orcid.org/0000-0001-9103-1686, Redman, James E. ORCID: https://orcid.org/0000-0001-5492-2869, Cross, Deborah L., Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Can, Ilona, Davies, Bethan, Hashimdeen, Shaikh Shimaz, Reid, Reiss, Llewellyn-Lacey, Sian, Miners, Kelly L., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Lissina, Anya, Brown, Paul E., Wooldridge, Linda, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 2021. Synthetic peptides with inadvertent chemical modifications can activate potentially autoreactive T cells. The Journal of Immunology 207 (4) , pp. 1009-1017. 10.4049/jimmunol.2000756 |
Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Knezevic, Lea, Dockree, Tamsin, McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly L., Llewellyn-Lacey, Sian, Rubina, Anzelika, Francis, Ore, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Bridgeman, John S., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, van den Berg, Hugo A. and Wooldridge, Linda 2021. CD8 coreceptor-mediated focusing can reorder the agonist hierarchy of peptide ligands recognized via the T cell receptor. Proceedings of the National Academy of Sciences 118 (29) , e2019639118. 10.1073/pnas.2019639118 |
Heim, Kathrin, Binder, Benedikt, Sagar, Wieland, Dominik, Hensel, Nina, Llewellyn-Lacey, Sian, Gostick, Emma, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Emmerich, Florian, Vingerhoet, Hildegard, Kraft, Anke R M, Cornberg, Markus, Boettler, Tobias, Neumann-Haefelin, Christoph, Zehn, Dietmar, Bengsch, Bertram, Hofmann, Maike and Thimme, Robert 2021. TOX defines the degree of CD8+ T cell dysfunction in distinct phases of chronic HBV infection. Gut 70 , pp. 1550-1560. 10.1136/gutjnl-2020-322404 |
Nicoli, Francesco, Pacifico, Salvatore, Gallerani, Eleonora, Marzola, Erika, Albanese, Valentina, Finessi, Valentina, Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Appay, Victor, Marconi, Peggy, Guerrini, Remo, Caputo, Antonella and Gavioli, Riccardo 2021. Use of a novel peptide welding technology platform for the development of B- and T-Cell epitope-based vaccines. Vaccines 9 (5) , 526. 10.3390/vaccines9050526 |
Hensel, Nina, Gu, Zuguang, Sagar, Wieland, Dominik, Jechow, Katharina, Kemming, Janine, Llewellyn-Lacey, Sian, Gostick, Emma, Sogukpinar, Oezlem, Emmerich, Florian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Bengsch, Bertram, Boettler, Tobias, Neumann-Haefelin, Christoph, Eils, Roland, Conrad, Christian, Bartenschlager, Ralf, Grün, Dominic, Ishaque, Naveed, Thimme, Robert and Hofmann, Maike 2021. Memory-like HCV-specific CD8+ T cells retain a molecular scar after cure of chronic HCV infection. Nature Immunology 22 (2) , 229–239. 10.1038/s41590-020-00817-w |
Schulien, Isabel, Kemming, Janine, Oberhardt, Valerie, Wild, Katharina, Seidel, Lea M., Killmer, Saskia, Sagar, Daul, Franziska, Salvat Lago, Marilyn, Decker, Annegrit, Luxenburger, Hendrik, Binder, Benedikt, Bettinger, Dominik, Sogukpinar, Oezlem, Rieg, Siegbert, Panning, Marcus, Huzly, Daniela, Schwemmle, Martin, Kochs, Georg, Waller, Cornelius F., Nieters, Alexandra, Duerschmied, Daniel, Emmerich, Florian, Mei, Henrik E., Schulz, Axel Ronald, Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Boettler, Tobias, Bengsch, Bertram, Thimme, Robert, Hofmann, Maike and Neumann-Haefelin, Christoph 2021. Characterization of pre-existing and induced SARS-CoV-2-specific CD8+ T cells. Nature Medicine 27 (1) 10.1038/s41591-020-01143-2 |
Galletti, Giovanni, De Simone, Gabriele, Mazza, Emilia M.C., Puccio, Simone, Mezzanotte, Claudia, Bi, Timothy M., Davydov, Alexey N., Metsger, Maria, Scamardella, Eloise, Alvisi, Giorgia, Paoli, Federica De, Zanon, Veronica, Scarpa, Alice, Camisa, Barbara, Colombo, Federico S., Anselmo, Achile, Peano, Clelia, Polletti, Sara, Mavilio, Domenico, Gattinoni, Luca, Boi, Shannon K., Youngblood, Benjamin A., Jones, Rhiannon E., Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467, Gostick, Emma, Llewellyn-Lacey, Sian, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Chudakov, Dmitriy M., Newell, Evan W., Casucci, Monica and Lugli, Enrico 2020. Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans. Nature Immunology 21 , pp. 1552-1562. 10.1038/s41590-020-0791-5 |
Buggert, Marcus, Vella, Laura A., Nguyen, Son, Wu, Vincent H., Chen, Zeyu, Sekine, Takuya, Perez-Potti, André, Maldini, Colby R., Manne, Sasikanth, Darko, Samuel, Ransier, Amy, Kuri-Cervantes, Leticia, Japp, Alberto Sada, Brody, Irene Bukh, Ivarsson, Martin A., Gorin, Jean-Baptiste, Rivera-Ballesteros, Olga, Hertwig, Laura, Antel, Jack P., Johnson, Matthew E., Okoye, Afam, Picker, Louis, Vahedi, Golnaz, Sparrelid, Ernesto, Llewellyn-Lacey, Sian, Gostick, Emma, Sandberg, Johan K., Björkström, Niklas, Bar-Or, Amit, Dori, Yoav, Naji, Ali, Canaday, David H., Laufer, Terri M., Wells, Andrew D., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Frank, Ian, Douek, Daniel C., Wherry, E. John, Itkin, Maxim G. and Betts, Michael R. 2020. The identity of human tissue-emigrant CD8+ T cells. Cell 183 (7) , pp. 1946-1961. 10.1016/j.cell.2020.11.019 |
Weinfurter, Jason T., Graham, Michael E., Ericsen, Adam J., Matschke, Lea M., Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Wiseman, Roger W. and Reynolds, Matthew R. 2020. Identifying a minor histocompatibility antigen in mauritian cynomolgus macaques encoded by APOBEC3C. Frontiers in Immunology 11 , 586251. 10.3389/fimmu.2020.586251 |
Sekine, Takuya, Perez-Potti, André, Rivera-Ballesteros, Olga, Strålin, Kristoffer, Gorin, Jean-Baptiste, Olsson, Annika, Llewellyn-Lacey, Sian, Kamal, Habiba, Bogdanovic, Gordana, Muschiol, Sandra, Wullimann, David J., Kammann, Tobias, Emgård, Johanna, Parrot, Tiphaine, Folkesson, Elin, Rooyackers, Olav, Eriksson, Lars I., Henter, Jan-Inge, Sönnerborg, Anders, Allander, Tobias, Albert, Jan, Nielsen, Morten, Klingström, Jonas, Gredmark-Russ, Sara, Björkström, Niklas K., Sandberg, Johan K., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Ljunggren, Hans-Gustaf, Aleman, Soo, Buggert, Marcus, Akber, Mira, Berglin, Lena, Bergsten, Helena, Brighenti, Susanna, Brownlie, Demi, Butrym, Marta, Chambers, Benedict, Chen, Puran, Jeannin, Martin Cornillet, Grip, Jonathan, Gomez, Angelica Cuapio, Dillner, Lena, Lozano, Isabel Diaz, Dzidic, Majda, Tullberg, Malin Flodström, Färnert, Anna, Glans, Hedvig, Haroun-Izquierdo, Alvaro, Henriksson, Elizabeth, Hertwig, Laura, Kalsum, Sadaf, Kokkinou, Efthymia, Kvedaraite, Egle, Loreti, Marco, Lourda, Magalini, Maleki, Kimia, Malmberg, Karl-Johan, Marquardt, Nicole, Maucourant, Christopher, Michaelsson, Jakob, Mjösberg, Jenny, Moll, Kirsten, Muva, Jagadees, Mårtensson, Johan, Nauclér, Pontus, Norrby-Teglund, Anna, Medina, Laura Palma, Persson, Björn, Radler, Lena, Ringqvist, Emma, Sandberg, John Tyler, Sohlberg, Ebba, Soini, Tea, Svensson, Mattias, Tynell, Janne, Varnaite, Renata, Kries, Andreas Von and Unge, Christian 2020. Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19. Cell 183 (1) , pp. 158-168. 10.1016/j.cell.2020.08.017 |
Passaes, Caroline, Millet, Antoine, Madelain, Vincent, Monceaux, Valérie, David, Annie, Versmisse, Pierre, Sylla, Naya, Gostick, Emma, Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Blancher, Antoine, Dereuddre-Bosquet, Nathalie, Desjardins, Delphine, Pancino, Gianfranco, Le Grand, Roger, Lambotte, Olivier, Müller-Trutwin, Michaela, Rouzioux, Christine, Guedj, Jérémie, Avettand-Fenoel, Véronique, Vaslin, Bruno and Sáez-Cirión, Asier 2020. Optimal maturation of the SIV-Specific CD8+ T cell response after primary infection is associated with natural control of SIV: ANRS SIC study. Cell Reports 32 (12) , 108174. 10.1016/j.celrep.2020.108174 |
Sekine, Takuya, Perez-Potti, André, Nguyen, Son, Gorin, Jean-Baptiste, Wu, Vincent H., Gostick, Emma, Llewellyn-Lacey, Sian, Hammer, Quirin, Falck-Jones, Sara, Vangeti, Sindhu, Yu, Meng, Smed-Sörensen, Anna, Gaballa, Ahmed, Uhlin, Michael, Sandberg, Johan K., Brander, Christian, Nowak, Piotr, Goepfert, Paul A., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Betts, Michael R. and Buggert, Marcus 2020. TOX is expressed by exhausted and polyfunctional human effector memory CD8+ T cells. Science Immunology 5 (49) , eaba7918. 10.1126/sciimmunol.aba7918 |
Pearson, Frances E., Tullett, Kirsteen M., Leal-Rojas, Ingrid M., Haigh, Oscar L., Masterman, Kelly-Anne, Walpole, Carina, Bridgeman, John S., McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly, Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Tunger, Antje, Schmitz, Marc, Miles, John J, Lahoud, Mireille H and Radford, Kristen J 2020. Human CLEC9A antibodies deliver Wilms' tumor 1 (WT1) antigen to CD141+ dendritic cells to activate naïve and memory WT1‐specific CD8+ T cells. Clinical and Translational Immunology 9 10.1002/cti2.1141 |
Tauber, C, Schultheiss, M, De Luca, R, Buettner, N, Llewellyn-Lacey, S, Emmerich, F, Zehe, S, Price, D A ORCID: https://orcid.org/0000-0001-9416-2737, Neumann-Haefelin, C, Schmitt-Graeff, A, Hoffman, M and Thimme, R 2019. Inefficient induction of circulating TAA-specific CD8+ T-cell responses in hepatocellular carcinoma. Oncotarget 10 (50) , pp. 5194-5206. 10.18632/oncotarget.27146 |
Schuch, Anita, Salimi Alizei, Elahe, Heim, Kathrin, Wieland, Dominik, Kiraithe, Michael Muthamia, Kemming, Janine, Llewellyn-Lacey, Sian, Sogukpinar, Özlem, Ni, Yi, Urban, Stephan, Zimmermann, Peter, Nassal, Michael, Emmerich, Florian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Bengsch, Bertram, Luxenburger, Hendrik, Neumann-Haefelin, Christoph, Hofmann, Maike and Thimme, Robert 2019. Phenotypic and functional differences of HBV core-specific versus HBV polymerase-specific CD8+ T cells in chronically HBV-infected patients with low viral load. Gut 68 , pp. 905-915. 10.1136/gutjnl-2018-316641 |
McLaren, James ORCID: https://orcid.org/0000-0002-7021-5934, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Marsden, Morgan, Miners, Kelly L., Llewellyn-Lacey, Sian, Grant, Emma J., Rubina, Anzelika, Gimeno Brias, Silvia, Gostick, Emma, Stacey, Maria A., Orr, Selinda J., Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337 2019. IL-33 augments virus-specific memory T Cell inflation and potentiates the efficacy of an attenuated cytomegalovirus-based vaccinea. Journal of Immunology 202 (3) , pp. 943-955. 10.4049/jimmunol.1701757 |
Martin, Maureen P., Naranbhai, Vivek, Shea, Patrick R., Qi, Ying, Ramsuran, Veron, Vince, Nicolas, Gao, Xiaojiang, Thomas, Rasmi, Brumme, Zabrina L., Carlson, Jonathan M., Wolinsky, Steven M., Goedert, James J., Walker, Bruce D., Segal, Florencia P., Deeks, Steven G., Haas, David W., Migueles, Stephen A., Connors, Mark, Michael, Nelson, Fellay, Jacques, Gostick, Emma, Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Lafont, Bernard A., Pymm, Phillip, Saunders, Philippa M., Widjaja, Jacqueline, Wong, Shu Cheng, Vivian, Julian P., Rossjohn, Jamie ORCID: https://orcid.org/0000-0002-2020-7522, Brooks, Andrew G. and Carrington, Mary 2018. Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1. Journal of Clinical Investigation 128 (5) , p. 1903. 10.1172/JCI98463 |
Lissina, Anna, McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934, Ilander, Mette, Andersson, Emma I., Lewis, Catherine S., Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Herman, Andrew, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Llewellyn-Lacey, Sian, Miners, Kelly L., Gostick, Emma, Melenhorst, J. Joseph, Barrett, A. John, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Mustjoki, Satu and Wooldridge, Linda 2018. Divergent roles for antigenic drive in the aetiology of primary versus dasatinib-associated CD8+ TCR-Vβ+ expansions. Scientific Reports 8 (1) , 2534. 10.1038/s41598-017-18062-x |
Dockree, Tamsin, Holland, Christopher J., Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, McLaren, James Edward ORCID: https://orcid.org/0000-0002-7021-5934, Van Den Berg, Hugo A., Gostick, Emma, Llewellyn-Lacey, Sian, Man, Stephen Tzekwung ORCID: https://orcid.org/0000-0001-9103-1686, Bailey, Mick, Burrows, Scott, Price, David ORCID: https://orcid.org/0000-0001-9416-2737 and Wooldridge, Linda 2017. CD8+ T-cell specificity is compromised at a defined MHCI/CD8 affinity threshold. Immunology and Cell Biology 95 (1) , pp. 68-76. 10.1038/icb.2016.85 |
Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Pearson, James ORCID: https://orcid.org/0000-0002-2867-2269, Gras, Stephanie, Van den berg, Hugo, Lissina, Anya, Llewellyn-Lacey, Sian, Willis, Mark ORCID: https://orcid.org/0000-0003-3024-6063, Dockree, Tamsin, McLaren, James ORCID: https://orcid.org/0000-0002-7021-5934, Ekeruche-Makinde, Julia, Gostick, Emma, Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909, Burrows, Scott, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Peakman, Mark, Skowera, Ania and Wooldridge, Linda 2016. Targeted suppression of autoreactive CD8+ T-cell activation using blocking anti-CD8 antibodies. Scientific Reports 6 , 35332. 10.1038/srep35332 |
Szomolay, Barbara ORCID: https://orcid.org/0000-0002-5375-5533, Liu, Jie, Brown, Paul E., Miles, John J., Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Llewellyn-Lacey, Sian, Dolton, Garry, Ekeruche-Makinde, Julia, Lissina, Anya, Schauenburg, Andrea J., Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Burrows, Scott R., Roederer, Mario, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Wooldridge, Linda and van den Berg, Hugo A. 2016. Identification of human viral protein-derived ligands recognized by individual MHCI-restricted T-cell receptors. Immunology and Cell Biology 94 (6) , pp. 573-582. 10.1038/icb.2016.12 |
van den Berg, Hugo A., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly, Laugel, Bruno, Llewellyn-Lacey, Sian, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Gostick, Emma, Wooldridge, Linda, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Bridgeman, John S. and Price, David ORCID: https://orcid.org/0000-0001-9416-2737 2013. Cellular-level versus receptor-level response threshold hierarchies in T-cell activation. Frontiers in Immunology 4 , 250. 10.3389/fimmu.2013.00250 |
Eukeruche-Makinde, Julia, Miles, John J., Van Den Berg, Hugo A., Skowera, Ania, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Dolton, Garry Michael, Schauenburg, Andrea, Tan, Mai Ping, Pentier, Johanne, Llewellyn-Lacey, Sian, Miles, Kim M., Bulek, Anna, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Dockree, Tamsin, Trimby, Andrew R., Bailey, Mick, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Rossjohn, Jamie ORCID: https://orcid.org/0000-0002-2020-7522, Peakman, Mark, Burrows, Scott, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 and Wooldridge, Linda 2013. Peptide length determines the outcome of TCR/peptide-MHCI engagement. Blood -New York- 121 (7) , pp. 1112-1123. 10.1182/blood-2012-06-437202 |
Ekeruche, Julia, Miles, John James, van den Berg, Hugo A., Skowera, Ania, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Dolton, Garry Michael, Schauenburg, Andrea J. A., Tan, Mai Ping, Pentier, Johanne, Llewellyn-Lacey, Sian, Miles, Kim Michelle, Bulek, Anna Marta, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Williams, Tamsin, Trimby, Andrew R., Bailey, Mick, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Rossjohn, Jamie ORCID: https://orcid.org/0000-0002-2020-7522, Peakman, Mark, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Burrows, Scott R., Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 and Wooldridge, Linda 2013. Peptide length determines the outcome of TCR/peptide-MHCI engagement. Blood 121 (7) , pp. 1112-1123. 10.1182/blood-2012-06-437202 |
Wooldridge, Linda, Ekeruche, Julia, van den Berg, Hugo A., Skowera, Anna, Miles, John James, Tan, Mai Ping, Dolton, Garry Michael, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Llewellyn-Lacey, Sian, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Peakman, Mark and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 2012. A single autoimmune T cell receptor recognizes more than a million different peptides. Journal of Biological Chemistry 287 (2) , pp. 1168-1177. 10.1074/jbc.M111.289488 |
Chong, Lee Kien, Aicheler, Rebecca, Llewellyn-Lacey, Sian, Tomasec, Peter, Brennan, Paul ORCID: https://orcid.org/0000-0001-8792-0499 and Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 2008. Proliferation and interleukin 5 production by CD8hiCD57+ T cells. European Journal of Immunology 38 (4) , pp. 995-1000. 10.1002/eji.200737687 |
Wilkinson, Gavin William Grahame ORCID: https://orcid.org/0000-0002-5623-0126, Tomasec, Peter, Stanton, Richard James ORCID: https://orcid.org/0000-0002-6799-1182, Armstrong, Melanie, Prod'homme, Virginie ORCID: https://orcid.org/0000-0002-9664-4710, Aicheler, Rebecca, McSharry, Brian P., Rickards, Carole R., Cochrane, Daniel, Llewellyn-Lacey, Sian, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Griffin, Cora A. and Davison, Andrew J. 2008. Modulation of natural killer cells by human cytomegalovirus. Journal of Clinical Virology 41 (3) , pp. 206-212. 10.1016/j.jcv.2007.10.027 |
Tomasec, Peter, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964, Davison, Andrew J., Vojtesek, Borivoj, Armstrong, Melanie, Griffin, Cora, McSharry, Brian Patrick, Morris, Rebecca J., Llewellyn-Lacey, Sian, Rickards, Carole Ruth, Nomoto, Akio, Sinzger, Christian and Wilkinson, Gavin William Grahame ORCID: https://orcid.org/0000-0002-5623-0126 2005. Downregulation of natural killer cell-activating ligand CD155 by human cytomegalovirus UL141. Nature Immunology 6 (2) , pp. 181-188. 10.1038/ni1156 |