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Number of items: 40.

French, Rhiannon, Hayward, Olivia, da Silva, Andreia Ribeiro, Robinson, Timothy, Seaton, Gillian and Clarkson, Richard ORCID: https://orcid.org/0000-0001-7389-8673 2025. Pharmacological inhibition of cFLIP targets breast cancer stem cells. Journal of Cancer Treatment and Diagnosis 8 (2) 10.29245/2578-2967/2025/2.1210
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Giancotti, Gilda, French, Rhiannon, Hayward, Olivia, Lee, Kok Yung, Robinson, Timothy, Ribeiro da Silva, Andreia M., Varnava, Athina, MacFarlane, Marion, Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Westwell, Andrew D. ORCID: https://orcid.org/0000-0002-5166-9236 and Brancale, Andrea 2025. The discovery of small-molecule inhibitors of cFLIP that sensitise tumour cells to TNF-related apoptosis-inducing ligand. Academia Oncology 2 (2) 10.20935/AcadOnco7680
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Turnham, Daniel J. ORCID: https://orcid.org/0000-0002-2540-7363, Mullen, Manisha S., Bullock, Nicholas P., Gilroy, Kathryn L., Richards, Anna E., Patel, Radhika, Quintela, Marcos, Meniel, Valerie S., Seaton, Gillian, Kynaston, Howard ORCID: https://orcid.org/0000-0003-1902-9930, Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Phesse, Toby J. ORCID: https://orcid.org/0000-0001-9568-4916, Nelson, Peter S., Haffner, Michael C., Staffurth, John N. ORCID: https://orcid.org/0000-0002-7834-3172 and Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843 2024. Development and characterisation of a new patient-derived Xenograft model of AR-negative metastatic asctration-resistant prostate cancer. Cells 13 (8) , 673. 10.3390/cells13080673
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Turnham, Daniel J. ORCID: https://orcid.org/0000-0002-2540-7363, Smith, Hannah and Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 2024. Suppression of Bcl3 disrupts viability of breast cancer cells through both p53-dependent and p53-independent mechanisms via loss of NF-κB signalling. Biomedicines 12 (1) , 143. 10.3390/biomedicines12010143
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Seaton, Gillian, Smith, Hannah, Brancale, Andrea, Westwell, Andrew D. ORCID: https://orcid.org/0000-0002-5166-9236 and Clarkson, Richard ORCID: https://orcid.org/0000-0001-7389-8673 2024. Multifaceted roles for BCL3 in cancer: a proto-oncogene comes of age. Molecular Cancer 23 (1) , 7. 10.1186/s12943-023-01922-8
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Soukupova, Jitka, Bordoni, Cinzia, Turnham, Daniel J. ORCID: https://orcid.org/0000-0002-2540-7363, Yang, William W., Seaton, Gillian, Gruca, Aleksandra, French, Rhiannon, Lee, Kok Yung, Varnava, Athina, Piggott, Luke, Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Westwell, Andrew D. ORCID: https://orcid.org/0000-0002-5166-9236 and Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 2021. The discovery of a novel anti-metastatic Bcl3 inhibitor. Molecular Cancer Therapeutics 10 (5) , pp. 775-786. 10.1158/1535-7163.MCT-20-0283
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Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Marlow, Gareth ORCID: https://orcid.org/0000-0002-7608-9086, Uusi-Kerttula, Hanni K., Seaton, Gillian, Piggott, Luke, Badder, Luned M., Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Chester, John D. ORCID: https://orcid.org/0000-0002-7830-3840 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761 2021. Efficient intravenous tumor targeting using the αvβ6 integrin-selective precision virotherapy Ad5NULL-A20. Viruses 13 (5) , 864. 10.3390/v13050864
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Turnham, Daniel J. ORCID: https://orcid.org/0000-0002-2540-7363, Yang, William W., Davies, Julia, Varnava, Athina, Ridley, Anne J., Conlan, R. Steven and Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 2020. Bcl-3 promotes multi-modal tumour cell migration via NF-kB1 mediated regulation of Cdc42. Carcinogenesis 41 (10) , pp. 1432-1443. 10.1093/carcin/bgaa005
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Kiraga, Lukasz, Cerutti, Gabriele, Braniewska, Agata, Strzemecki, Damian, Sas, Zuzanna, Boffi, Alberto, Savino, Carmelinda, Montemiglio, Linda Celeste, Turnham, Daniel ORCID: https://orcid.org/0000-0002-2540-7363, Seaton, Gillian, Bonamore, Alessandra, Clarkson, Richard ORCID: https://orcid.org/0000-0001-7389-8673, Dabkowski, Adam M., Paisey, Stephen J., Taciak, Bartlomiej, Kucharzewska, Paulina, Rygiel, Tomasz P. and Król, Magdalena 2020. Biodistribution PET/CT study of hemoglobin-DFO-89Zr complex in healthy and lung tumor-bearing mice. International Journal of Molecular Sciences 21 (14) , 4991. 10.3390/ijms21144991
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Healey, Gareth D., Pan-Castillo, Belen, Garcia-Parra, Jezabel, Davies, Julia, Roberts, Shaun, Jones, Eilir, Dhar, Kalyan, Nandanan, Sarika, Tofazzal, Nasima, Piggott, Luke, Clarkson, Richard ORCID: https://orcid.org/0000-0001-7389-8673, Seaton, Gillian, Frostell, Asa, Fagge, Tim, McKee, Colin, Margarit, Lavinia, Conlan, R. Steven and Gonzalez, Deyarina 2019. Antibody drug conjugates against the receptor for advanced glycation end products (RAGE), a novel therapeutic target in endometrial cancer. Journal for ImmunoTherapy of Cancer 7 (1) , 280. 10.1186/s40425-019-0765-z
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Legge, Danny N., Shephard, Alex P., Collard, Tracey J., Greenhough, Alexander, Chambers, Adam C., Clarkson, Richard W. ORCID: https://orcid.org/0000-0001-7389-8673, Paraskeva, Christos and Williams, Ann C. 2019. BCL-3 promotes a cancer stem cell phenotype by enhancing β-catenin signalling in colorectal tumour cells. Disease Models and Mechanisms 12 (3) , 037697. 10.1242/dmm.037697
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Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843, Li, Jason, Meniel, Valerie S., Fennell, Christina M., Waring, Paul, Montgomery, Karen G., Rebello, Richard J., Macpherson, Arthi A., Koushyar, Sarah, Furic, Luc, Cullinane, Carleen, Clarkson, Richard W. ORCID: https://orcid.org/0000-0001-7389-8673, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146, Simpson, Kaylene J., Phesse, Toby J. ORCID: https://orcid.org/0000-0001-9568-4916, Shepherd, Peter R., Humbert, Patrick O., Sansom, Owen J. and Phillips, Wayne A. 2018. Identification of Pik3ca mutation as a genetic driver of prostate cancer that cooperates with Pten loss to accelerate progression and castration-resistant growth. Cancer Discovery 8 (6) , pp. 764-779. 10.1158/2159-8290.CD-17-0867
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Piggott, Luke, Silva, Ana ORCID: https://orcid.org/0000-0002-1184-4909, Robinson, Timothy, Santiago-Gomez, Angelica, Simoes, Bruno M., Becker, Michael, Fichtner, Iduna, Andera, Ladislav, Young, Philippa, Morris, Christine, Barret-Lee, Peter, Alchami, Fouad, Piva, Marco, Vivanco, Maria d. M., Clarke, Robert B., Gee, Julia ORCID: https://orcid.org/0000-0001-6483-2015 and Clarkson, Richard ORCID: https://orcid.org/0000-0001-7389-8673 2018. Acquired resistance of ER-positive breast cancer to endocrine treatment confers an adaptive sensitivity to TRAIL through post-translational downregulation of c-FLIP. Clinical Cancer Research 24 (10) , pp. 2452-2463. 10.1158/1078-0432.CCR-17-1381
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Chen, Hung-Chang, Joalland, Noémie, Bridgeman, John S, Alchami, Fouad S, Jarry, Ulrich, Khan, Mohd Wajid A, Piggott, Luke, Shanneik, Yasmin, Li, Jianqiang, Herold, Marco J, Herrmann, Thomas, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Gallimore, Awen M. ORCID: https://orcid.org/0000-0001-6675-7004, Clarkson, Richard W. ORCID: https://orcid.org/0000-0001-7389-8673, Scotet, Emmanuel, Moser, Bernhard ORCID: https://orcid.org/0000-0002-4354-4572 and Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348 2017. Synergistic targeting of breast cancer stem-like cells by human γδ T cells and CD8+ T cells. Immunology and Cell Biology 95 (7) , pp. 620-629. 10.1038/icb.2017.21
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Yeo, Syn Kok, French, Rhiannon, Filomena, Spada and Clarkson, Richard ORCID: https://orcid.org/0000-0001-7389-8673 2017. Opposing roles of Nfkb2 gene products p100 and p52 in the regulation of breast cancer stem cells. Breast Cancer Research and Treatment 162 (3) , pp. 465-477. 10.1007/s10549-017-4149-0
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Yeo, Syn Kok, Ali, Ahmed Y., Hayward, Olivia A., Turnham, Daniel, Jackson, Troy, Bowen, Ifor D. and Clarkson, Richard ORCID: https://orcid.org/0000-0001-7389-8673 2016. Bisabolene, a sesquiterpene from the essential oil extract of opoponax (Commiphora guidottii), exhibits cytotoxicity in breast cancer cell lines. Phytotherapy Research 30 (3) , pp. 418-425. 10.1002/ptr.5543
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French, Rhiannon, Hayward, Olivia, Jones, Samuel, Yang, William and Clarkson, Richard ORCID: https://orcid.org/0000-0001-7389-8673 2015. Cytoplasmic levels of cFLIP determine a broad susceptibility of breast cancer stem/progenitor-like cells to TRAIL. Molecular Cancer 14 , 209. 10.1186/s12943-015-0478-y
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Ali, Ahmed Y., Yeo, Syn, Ellis, Sadie, Ade, Jamilla, Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Esa, Adam, Blain, Emma J. ORCID: https://orcid.org/0000-0001-8944-4254, Bowen, Ifor D. and Martin, Tracey A. ORCID: https://orcid.org/0000-0003-2690-4908 2015. Anti-metastatic and cytotoxic properties of frankincense and scented myrrh. Anticancer Research 35 (7) , pp. 4310-4311.

Piggott, Luke, Omidvar, Nader, Martí Pérez, Salvador, French, Rhiannon, Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348 and Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 2015. Erratum to: Suppression of apoptosis inhibitor c-FLIP selectively eliminates breast cancer stem cell activity in response to the anti-cancer agent, TRAIL. Breast Cancer Research 17 (1) , p. 96. 10.1186/s13058-015-0597-9
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Cowley, Michael, Garfield, Alastair S., Madon-Simon, Marta, Charalambous, Marika, Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Kendrick, Howard, Isles, Anthony Roger ORCID: https://orcid.org/0000-0002-7587-5712, Parry, Aled J., Carney, Sara, Oakey, Rebecca J., Heisler, Lora K., Moorwood, Kim, Wolf, Jason B. and Ward, Andrew 2014. Developmental programming mediated by complementary roles of imprinted Grb10 in mother and pup. PLoS Biology 12 (2) , e1001799. 10.1371/journal.pbio.1001799
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Wakefield, Alison Myfanwy, Soukupová, Jitka, Montagne, Amelie, Ranger, Jill, French, Rhiannon, Muller, William and Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 2013. Bcl3 selectively promotes metastasis of ErbB2-driven mammary tumors. Cancer Research 73 (2) , pp. 745-755. 10.1158/0008-5472.CAN-12-1321

Smalley, Matthew John ORCID: https://orcid.org/0000-0001-9540-1146, Piggott, Luke and Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 2013. Breast cancer stem cells: obstacles to therapy. Cancer Letters 338 (1) , pp. 57-62. 10.1016/j.canlet.2012.04.023

Soukupova, J., Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Westwell, Andrew D. ORCID: https://orcid.org/0000-0002-5166-9236 and Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 2012. Inhibitors of Bcl-3 as a novel therapeutic strategy for HER2+ breast cancer. European Journal of Cancer 48 (5) , S225-S225.

Piggott, Luke, Omidvar, Nader, Marti-Perez, Salvador, Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348 and Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 2011. Suppression of apoptosis inhibitor c-FLIP selectively eliminates breast cancer stem cell activity in response to the anti-cancer agent, TRAIL. Breast Cancer Research 13 (5) , R88. 10.1186/bcr2945
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Knight, James Christopher, Hallett, Andrew Jon, Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Paisey, Stephen James ORCID: https://orcid.org/0000-0002-2274-3708, Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 and Edwards, Peter Gerald ORCID: https://orcid.org/0000-0001-6999-753X 2011. Evaluation of a fluorescent derivative of AMD3100 and its interaction with the CXCR4 chemokine receptor. ChemBioChem 12 (17) , pp. 2692-2698. 10.1002/cbic.201100441

Kreuzaler, Peter A., Staniszewska, Anna D., Li, Wenjing, Omidvar, Nader, Kedjouar, Blandine, Turkson, James, Poli, Valeria, Flavell, Richard A., Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 and Watson, Christine J. 2011. Stat3 controls lysosomal-mediated cell death in vivo. Nature Cell Biology 13 (3) , pp. 303-309. 10.1038/ncb2171

Jasani, Bharat, Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015, Hutcheson, Iain Robert, Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Bartlett, J. and Barrett-Lee, Peter 2009. Resistance to HER2-directed trastuzumab therapy in breast cancer. Advances in Breast Cancer 6 (3) , pp. 11-18.

Wakefield, A., Piggott, Luke, Croston, D., Jiang, W. G. and Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 2008. Suppression of the NF-kappa B cofactor Bcl3 inhibits mammary epithelial cell apoptosis and, in breast tumours, correlates with poor prognosis. Breast Cancer Research 10 (S2) , O4. 10.1186/bcr1884
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Tiffen, P., Omidvar, Nader, Marquez, Nuria, Croston, D., Watson, C. and Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 2008. A dual role for Oncostatin M signalling in the differentiation and death of mammary epithelial cells in vivo. Molecular Endocrinology 22 (12) , pp. 2677-2688. 10.1210/me.2008-0097

Sykacek, P., Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Print, C., Furlong, R. and Micklem, G. 2007. Bayesian modelling of shared gene function. Bioinformatics 23 (15) , pp. 1936-1944. 10.1093/bioinformatics/btm280

Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Boland, Marion P., Kritikou, Ekaterini A., Lee, Jennifer M., Freeman, Tom C., Tiffen, Paul G. and Watson, Christine J. 2006. The genes induced by signal transducer and activators of transcription (STAT)3 and STAT5 in mammary epithelial cells define the roles of these STATs in mammary development. Molecular Endocrinology 20 (3) , pp. 675-685. 10.1210/me.2005-0392

Abell, Kathrine, Bilancio, Antonio, Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Tiffen, Paul G., Altaparmakov, Anton I., Burdon, Thomas G., Asano, Tomoichiro, Vanhaesebroeck, Bart and Watson, Christine J. 2005. Stat3-induced apoptosis requires a molecular switch in PI(3)K subunit composition. Nature Cell Biology Vol. 7 (4) , pp. 392-398. 10.1038/ncb1242

Sorrell, David A., Szymanowska, Malgorzata, Boutinaud, Marion, Robinson, Claire, Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Stein, Torsten, Flint, David J. and Kolb, Andreas F. 2005. Regulation of genes encoding proteolytic enzymes during mammary gland development. Journal of Dairy Research 72 (04) , pp. 433-441. 10.1017/S0022029905001202

Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Wayland, M. T., Lee, J., Freeman, T. and Watson, C. J. 2004. Gene expression profiling of mammary gland development reveals putative roles for death receptors and immune mediators in post-lactational regression. Breast Cancer Research 6 (2) , R92-R109.
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Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Corti, C., Ferraguti, F. and Xuereb, J.H. 2003. Gene structure of the human metabotropic glutamate receptor 5 and functional analysis of its multiple promoters in neuroblastoma and astroglioma cells. Journal of Biological Chemistry Vol. 2 (No.35) , pp. 33105-33119. 10.1074/jbc.M212380200

Kritikou, Ekaterini A., Sharkey, Andrew, Abell, Kathrine, Came, Paul J., Anderson, Elizabeth, Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 and Watson, Christine J. 2003. A dual, non-redundant, role for LIF as a regulator of development and STAT3-mediated cell death in mammary gland. Development 130 (15) , pp. 3459-3468. 10.1242/dev.00578

Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 and Watson, Christine J. 2003. Microarray analysis of the involution switch. Journal of Mammary Gland Biology and Neoplasia 8 (3) , pp. 309-319. 10.1023/B:JOMG.0000010031.53310.92

Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673 2002. lkB kinase alpha: a link in the chain of the mammary cycle. Breast Cancer Research 4 , 173. 10.1186/bcr446

Gordon, K., Binas, B., Chapman, R. S., Kurian, K. M., Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Clark, A. J., Lane, E. B. and Watson, C. J. 2000. A novel cell culture model for studying differentiation and apoptosis in the mouse mammary gland. Breast Cancer Research 2 , pp. 222-235. 10.1186/bcr57
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Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Heeley, JoannaLL., Chapman, Rachel, Aillet, Fabienne, Hay, Ronald T., Wyllie, Andrew and Watson, Christine J. 2000. NF-kappa B inhibits apoptosis in murine mammary epithelia. Journal of Biological Chemistry 275 (17) , pp. 12737-12742. 10.1074/jbc.275.17.12737

This list was generated on Thu Oct 30 14:12:18 2025 GMT.


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