Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Tyrrell, Victoria J., Burston, James J., Johnson, Sam R. C., Aldrovandi, Maceler, Alvarez-Jarreta, Jorge, Inglis, Rossa, Leonard, Adam, Fice, Lydia, Costales, Jeremie, Vidal-Puig, Antonio, Protty, Majd, Guy, Carol, Andrews, Robert, Szomolay, Barbara ORCID: https://orcid.org/0000-0002-5375-5533, Cossins, Ben C., Cardus Figueras, Ana, Carobbio, Stefania, Jones, Simon A. ORCID: https://orcid.org/0000-0001-7297-9711 and O’Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460
2025.
12/15-lipoxygenase orchestrates murine wound healing via PPARγ-activating oxylipins acting holistically to dampen inflammation.
Proceedings of the National Academy of Sciences
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10.1073/pnas.2502640122
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Correia, Banny, Pontes, João Guilherme, Torrinhas, Raquel Susana, Val, Adalberto Luis, Thomas, Christopher Paul ORCID: https://orcid.org/0000-0001-5840-8613 and Tasic, Ljubica
2024.
Evaluation of the Amazon River seasonal influences on Glycerophospholipids in wild fish.
Journal of the Brazilian Chemical Society
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10.21577/0103-5053.20240015
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O’Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Schebb, Nils H., Milne, Ginger L., Murphy, Michael P., Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Steinhilber, Dieter, Gelhaus, Stacy L., Kühn, Hartmut, Gelb, Michael H., Jakobsson, Per-Johan, Blair, Ian A., Murphy, Robert C., Freeman, Bruce A., Brash, Alan R. and FitzGerald, Garret A.
2023.
Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their presence in biological samples.
Nature Communications
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10.1038/s41467-023-41766-w
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Moukachar, Ahmad, Harvey, Katie, Roke, Eva, Sloan, Katherine, Pool, Cameron, Moola, Shabbir, Alshukri, Ameer, Jarvis, Danielle, Crews‐Rees, Phoebe, McDermott, Grace, Evans, Lluan, Li, Jin ORCID: https://orcid.org/0000-0002-4672-6806, Thomas, Christopher ORCID: https://orcid.org/0000-0001-5840-8613, Coulman, Sion ORCID: https://orcid.org/0000-0002-1277-7584 and Castell, Oliver ORCID: https://orcid.org/0000-0002-6059-8062
2023.
Development and evaluation of a low‐cost lego 3d bioprinter: from building‐blocks to building blocks of life.
Advanced Materials Technologies
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10.1002/admt.202100868
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Tyrrell, Victoria J., Ali, Faraz, Boeglin, William E., Andrews, Robert, Burston, James, Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924, Ingram, John R., Murphy, Robert C., Piguet, Vincent, Brash, Alan R., O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 and Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613
2021.
Lipidomic and transcriptional analysis of the Linoleoyl-omega-Hydroxyceramide biosynthetic pathway in human psoriatic lesions.
Journal of Lipid Research
62
, 100094.
10.1016/j.jlr.2021.100094
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Chiba, Takahito, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Calcutt, M. Wade, Boeglin, William E., O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 and Brash, Alan R.
2016.
The precise structures and stereochemistry of trihydroxy-linoleates esterified in human and porcine epidermis and their significance in skin barrier function: Implication of an epoxide hydrolase in the transformations of linoleate.
Journal of Biological Chemistry
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10.1074/jbc.M115.711267
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Hinz, Christine, Aldrovandi, Maceler, Uhlson, Charis, Marnett, Lawrence J., Longhurst, Hilary J., Warner, Timothy D., Alam, Saydul, Slatter, David A., Lauder, Sarah N., Allen-Redpath, Keith, Collins, Peter W. ORCID: https://orcid.org/0000-0002-6410-1324, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613 and O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460
2016.
Human platelets utilize cycloxygenase-1 to generate dioxolane A3, a neutrophil activating eicosanoid.
Journal of Biological Chemistry
291
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10.1074/jbc.M115.700609
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McCully, Michelle L., Collins, Paul J., Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Billen, Jaak, O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460 and Moser, Bernhard ORCID: https://orcid.org/0000-0002-4354-4572
2015.
Skin metabolites define a new paradigm in the localization of skin tropic memory T cells.
Journal of Immunology
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10.4049/jimmunol.1402961
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Morgan, Alwena H., Hammond, Victoria J., Sakoh-Nakatogawa, Machiko, Ohsumi, Yoshinori, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Blanchet, Fabien, Piguet, Vincent, Kiselyov, Kirill and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460
2015.
A novel role for 12/15-lipoxygenase in regulating autophagy.
Redox Biology
4
, pp. 40-47.
10.1016/j.redox.2014.11.005
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Muñoz-Garcia, Agustí, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Keeney, Diane S., Zheng, Yuxiang and Brash, Alan R.
2014.
The importance of the lipoxygenase-hepoxilin pathway in the mammalian epidermal barrier.
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
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10.1016/j.bbalip.2013.08.020
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Clark, Stephen Robert ORCID: https://orcid.org/0000-0001-5907-9671, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Hammond, Victoria Jayne, Aldrovandi, Maceler, Wilkinson, Gavin William Grahame ORCID: https://orcid.org/0000-0002-5623-0126, Hart, Keith William, Murphy, Robert C., Collins, Peter William ORCID: https://orcid.org/0000-0002-6410-1324 and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460
2013.
Characterization of platelet aminophospholipid externalization reveals fatty acids as molecular determinants that regulate coagulation.
Proceedings of the National Academy of Sciences of the United States of America
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10.1073/pnas.1222419110
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Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Boeglin, William E., Garcia-Diaz, Yoel, O'Donnell, Valerie B. and Brash, Alan R.
2013.
Steric analysis of epoxyalcohol and trihydroxy derivatives of 9-hydroperoxy-linoleic acid from hematin and enzymatic synthesis.
Chemistry and Physics of Lipids
167
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10.1016/j.chemphyslip.2013.01.002
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Hammond, Victoria Jayne, Morgan, Alwena H., Lauder, Sarah Nicol, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Brown, Sarah, Freeman, Bruce A., Lloyd, Clare M., Davies, Jane, Bush, Andrew, Levonen, Anna-Liisa, Kansanen, Emilia, Villacorta, Luis, Chen, Y. Eugene, Porter, Ned, Garcia-Diaz, Yoel M., Schopfer, Francisco J. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460
2012.
Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-γ.
Journal of Biological Chemistry
287
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10.1074/jbc.M112.405407
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Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613 and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460
2012.
Oxidized phospholipid signaling in immune cells.
Current Opinion in Pharmacology
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10.1016/j.coph.2012.02.013
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Zulfakar, Mohd Hanif, Alex, Aneesh, Povazay, Boris, Drexler, Wolfgang, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Porter, Rebecca M. ORCID: https://orcid.org/0000-0001-6748-0916 and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2011.
In vivo response of GsdmA3Dfl/+ mice to topically applied anti-psoriatic agents: effects on epidermal thickness, as determined by optical coherence tomography and H&E staining.
Experimental Dermatology
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10.1111/j.1600-0625.2010.01233.x
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Ruge, Fiona, Glavini, Aikaterini, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Richards, Hannah E., Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Philpott, Michael P. and Porter, Rebecca ORCID: https://orcid.org/0000-0001-6748-0916
2011.
Delineating immune-mediated mechanisms underlying hair follicle destruction in the mouse mutant defolliculated.
Journal of Investigative Dermatology
131
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, pp. 572-579.
10.1038/jid.2010.379
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Trostchansky, A., Bonilla, L., Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Marnett, L. J., Radi, R. and Rubbo, H.
2011.
Nitroarachidonic Acid, a Novel Peroxidase Inhibitor of Prostaglandin Endoperoxide H Synthases 1 and 2.
Journal of Biological Chemistry
286
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10.1074/jbc.M110.154518
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Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Morgan, Lloyd T., Maskrey, Ben, Murphy, Robert C., Kuhn, Hartmut, Hazen, Stanley L., Goodall, Alison H., Hamali, Hassan A., Collins, Peter William ORCID: https://orcid.org/0000-0002-6410-1324 and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460
2010.
Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation.
Journal of Biological Chemistry
285
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, pp. 6891-6903.
10.1074/jbc.M109.078428
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Morgan, Lloyd T., Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Kühn, Hartmut and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460
2010.
Thrombin-activated human platelets acutely generate oxidized docosahexaenoic-acid-containing phospholipids via 12-lipoxygenase.
Biochemical Journal
431
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, pp. 141-148.
10.1042/BJ20100415
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Morgan, Alwena Haf, Hammond, Victoria Jayne, Morgan, Lloyd, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Tallman, Keri A., Garcia-Diaz, Yoel Ruslan, McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Serpi, Michaela ORCID: https://orcid.org/0000-0002-6162-7910, Porter, Ned A., Murphy, Robert C. and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460
2010.
Quantitative assays for esterified oxylipins generated by immune cells.
Nature Protocols
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10.1038/nprot.2010.162
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Gregory, L. G., Causton, B., Murdoch, J. R., Mathie, S. A., O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Priest, F. M., Quint, D. J. and Lloyd, C. M.
2009.
Inhaled house dust mite induces pulmonary T helper 2 cytokine production.
Clinical and Experimental Allergy
39
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, pp. 1597-1610.
10.1111/j.1365-2222.2009.03302.x
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Morgan, Alwena Haf, Dioszeghy, Vincent, Maskrey, Benjamin, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Clark, Stephen Robert ORCID: https://orcid.org/0000-0001-5907-9671, Mathie, Sara A., Lloyd, Clare M., Kuhn, Hartmut, Topley, Nicholas, Coles, Barbara, Taylor, Philip Russel ORCID: https://orcid.org/0000-0003-0163-1421, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711 and O'Donnell, Valerie Bridget ORCID: https://orcid.org/0000-0003-4089-8460
2009.
Phosphatidylethanolamine-esterified eicosanoids in the mouse: tissue localization and inflammation-dependent formation in Th-2 disease.
Journal of Biological Chemistry
284
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10.1074/jbc.M109.021634
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Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777 and Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613
2007.
Probing the skin permeation of eicosapentaenoic acid and ketoprofen 2. Comparative depth profiling and metabolism of eicosapentaenoic acid.
European Journal of Pharmaceutics and Biopharmaceutics
67
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10.1016/j.ejpb.2006.11.024
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Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Davison, Zoe and Heard, Christopher Martin ORCID: https://orcid.org/0000-0001-9703-9777
2007.
Probing the skin permeation of fish oil/EPA and ketoprofen-3. Effects on epidermal COX-2 and LOX.
Prostaglandins Leukotrienes & Essential Fatty Acids
76
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10.1016/j.plefa.2007.05.002
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Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613 and Heard, Christopher Martin ORCID: https://orcid.org/0000-0001-9703-9777
2007.
Probing the skin permeation of eicosapentaenoic acid and ketoprofen - 2. Comparative depth profiling and metabolism of eicosapentaenoic acid.
European Journal of Pharmaceutics and Biopharmaceutics
67
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, pp. 156-165.
10.1016/j.ejpb.2006.11.024
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Heard, Charles M., Kung, Denise and Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613
2006.
Skin penetration enhancement of mefenamic acid by ethanol and 1,8-cineole can be explained by the ‘pull’ effect.
International Journal of Pharmaceutics
321
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10.1016/j.ijpharm.2006.05.018
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Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613
2006.
Transcutaneous delivery of anti-arthritic agents.
PhD Thesis,
Cardiff University.
|
|
|
Richards, Helen, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, Bowen, Jenna L. ORCID: https://orcid.org/0000-0003-1964-6832 and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2006.
In-vitro transcutaneous delivery of ketoprofen and polyunsaturated fatty acids from a pluronic lecithin organogel vehicle containing fish oil.
African Journal of Pharmacy and Pharmacology
58
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, pp. 903-908.
10.1211/jpp.58.7.0004
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Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777, Johnson, Sarah, Moss, Gary and Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613
2006.
In vitro transdermal delivery of caffeine, theobromine, theophylline and catechin from extract of Guarana, Paullinia Cupana.
International Journal of Pharmaceutics
317
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10.1016/j.ijpharm.2006.02.042
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Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777, Gallagher, Simon John, Congiatu, Costantino, Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613, McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Nemcova, Marta and Nouskova, Tereza
2005.
Preferential π–π complexation between tamoxifen and borage oil/γ linolenic acid: transcutaneous delivery and NMR spectral modulation.
International Journal of Pharmaceutics
302
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, pp. 47-55.
10.1016/j.ijpharm.2005.06.013
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Ho, Suzanna, Calder, Richard J., Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613 and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2004.
In-vitro transcutaneous delivery of tamoxifen and γ-linolenic acid from borage oil containing ethanol and 1,8-cineole.
Pharmacy and Pharmacology
56
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, pp. 1357-1364.
10.1211/0022357044599
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Batchelder, R. J., Calder, R. J., Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613 and Heard, Charles Martin ORCID: https://orcid.org/0000-0001-9703-9777
2004.
In vitro transdermal delivery of the major catechins and caffeine from extract of Camellia sinensis.
International Journal of Pharmaceutics
283
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, pp. 45-51.
10.1016/j.ijpharm.2004.06.007
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Davidge, Janette, Thomas, Christopher P. ORCID: https://orcid.org/0000-0001-5840-8613 and Williams, David R.
2001.
Conditional formation constants or chemical speciation data?
Chemical Speciation and Bioavailability
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10.3184/095422901782775390
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