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Number of items: 146.

Zhang, Luyao, Wang, Pai, Huang, Juan, Xing, Yanpeng, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Suo, Jian and Wen, Li 2024. Gut microbiota and therapy for obesity and type 2 diabetes. Frontiers in Endocrinology 15 , 1333778. 10.3389/fendo.2024.1333778
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Pearson, James Alexander ORCID: https://orcid.org/0000-0002-2867-2269, Hu, Youjia, Peng, Jian, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2024. TLR5-deficiency controls dendritic cell subset development in an autoimmune diabetes-susceptible model. Frontiers in Immunology 15 , 1333967. 10.3389/fimmu.2024.1333967
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Hanna, Stephanie J., Thayer, Terri C., Robinson, Emma J. S., Vinh, Ngoc-Nga, Williams, Nigel ORCID: https://orcid.org/0000-0003-1177-6931, Landry, Laurie G., Andrews, Robert, Siah, Qi Zhuang, Leete, Pia, Wyatt, Rebecca, McAteer, Martina A., Nakayama, Maki, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Yang, Jennie H. M., Tree, Timothy I. M., Ludvigsson, Johnny, Dayan, Colin M. ORCID: https://orcid.org/0000-0002-6557-3462 and Tatovic, Danijela ORCID: https://orcid.org/0000-0002-3879-2686 2023. Single-cell RNAseq identifies clonally expanded antigen-specific T-cells following intradermal injection of gold nanoparticles loaded with diabetes autoantigen in humans. Frontiers in Immunology 14 , 1276255. 10.3389/fimmu.2023.1276255
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Pearson, James A. ORCID: https://orcid.org/0000-0002-2867-2269, Peng, Jian, Huang, Juan, Yu, Xiaoqing, Tai, Ningwen, Hu, Youjia, Sha, Sha, Flavell, Richard A., Zhao, Hongyu, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2023. NLRP6 deficiency expands a novel CD103 + B cell population that confers immune tolerance in NOD mice. Frontiers in Immunology 14 , 1147925. 10.3389/fimmu.2023.1147925
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Okada, Mirei, Zhang, Vivian, Loaiza Naranjo, Jeniffer D., Tillett, Bree J., Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Steptoe, Raymond J., Bergot, Anne‐Sophie and Hamilton‐Williams, Emma E. 2023. Islet‐specific CD8+ T cells gain effector function in the gut lymphoid tissues via bystander activation not molecular mimicry. Immunology & Cell Biology 101 (1) , pp. 36-48. 10.1111/imcb.12593
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Pearson, James A. ORCID: https://orcid.org/0000-0002-2867-2269, Ding, Heyuan, Hu, Changyun, Peng, Jian, Galuppo, Brittany, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Caprio, Sonia, Santoro, Nicola and Wen, Li 2022. IgM-associated gut bacteria in obesity and type 2 diabetes in C57BL/6 mice and humans. Diabetologia 65 (8) , pp. 1398-1411. 10.1007/s00125-022-05711-8
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Chan, Karl, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Pearson, James Alexander ORCID: https://orcid.org/0000-0002-2867-2269 2022. Circadian rhythms and pancreas physiology: A review. Frontiers in Endocrinology 13 , 920261. 10.3389/fendo.2022.920261
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Majewska-Szczepanik, Monika, Kowalczyk, Paulina, Marcinska, Katarzyna, Strzepa, Anna, Lis, Grzegorz J., Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Szczepanik, Marian and Wen, Li 2022. Obesity aggravates contact hypersensitivity reaction in mice. Contact Dermatitis 87 (1) , pp. 28-39. 10.1111/cod.14088
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Jia, Jianxin, Kang, Qi, Liu, Shunzhi, Song, Yabin, Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845, Qiu, Yingkun and Li, Mingyu 2022. Artemether and aspterric acid induce pancreatic alpha cells to transdifferentiate into beta cells in zebrafish. British Journal of Pharmacology 179 (9) , pp. 1962-1977. 10.1111/bph.15769
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Green, E. Allison, Cooke, Anne C., Piganelli, Jon D., Richardson, Sarah J., Wen, Li and Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 2022. Editorial: Immunopathology of Type 1 Diabetes. Frontiers in Immunology 13 , 852963. 10.3389/fimmu.2022.852963
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Boldison, Joanne, Long, Anna E., Aitken, Rachel J., Wilson, Isabel V., Megson, Clare, Hanna, Stephanie J., Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Gillespie, Kathleen M. 2022. Activated but functionally impaired memory Tregs are expanded in slow progressors to type 1 diabetes. Diabetologia 65 , 343–355. 10.1007/s00125-021-05595-0
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Huang, Juan, Pearson, James Alexander ORCID: https://orcid.org/0000-0002-2867-2269, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Wen, Li and Zhou, Zhiguang 2022. Innate immunity in latent autoimmune diabetes in adults (LADA). Diabetes/Metabolism Research and Reviews 38 (1) , e3480. 10.1002/dmrr.3480
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Roy Chowdhury, Sharmistha, Thomas, Rebecca L., Dunseath, Gareth J., Luzio, Stephen D., Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Owens, David R. 2022. Incidence of diabetic retinopathy in newly diagnosed subjects with type 2 diabetes mellitus over 5 years: Contribution of B-cell function. Journal of Diabetes and its Complications 36 (1) , 108028. 10.1016/j.jdiacomp.2021.108028
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Tatovic, D. ORCID: https://orcid.org/0000-0002-3879-2686, McAteer, M. A., Barry, J., Barrientos, A., Rodríguez Terradillos, K., Perera, I., Kochba, E., Levin, Y., Dul, M., Coulman, S. A. ORCID: https://orcid.org/0000-0002-1277-7584, Birchall, J. C. ORCID: https://orcid.org/0000-0001-8521-6924, von Ruhland, C., Howell, A., Stenson, R., Alhadj Ali, M., Luzio, S. D., Dunseath, G., Cheung, W. Y., Holland, G., May, K., Ingram, J. R. ORCID: https://orcid.org/0000-0002-5257-1142, Chowdhury, M. M. U., Wong, F. S. ORCID: https://orcid.org/0000-0002-2812-8845, Casas, R., Dayan, C. ORCID: https://orcid.org/0000-0002-6557-3462 and Ludvigsson, J. 2022. Safety of the use of gold nanoparticles conjugated with proinsulin peptide and administered by hollow microneedles as an immunotherapy in Type 1 diabetes. Immunotherapy Advances 2 (1) , ltac002. 10.1093/immadv/ltac002
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Buzzetti, Raffaella, Maddaloni, Ernesto, Gaglia, Jason Gaglia, Leslie, R. David, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Boehm, Bernhard O. 2022. Adult-onset autoimmune diabetes. Nature Reviews Disease Primers 8 , 63. 10.1038/s41572-022-00390-6
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Quinn, Lauren M., Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Narendran, Parth 2021. Environmental determinants of type 1 diabetes: from association to proving causality. Frontiers in Immunology 12 , 737964. 10.3389/fimmu.2021.737964
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Boldison, Joanne and Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 2021. Regulatory B cells: role in type 1 diabetes. Frontiers in Immunology 12 , 746187. 10.3389/fimmu.2021.746187
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Pearson, James Alexander ORCID: https://orcid.org/0000-0002-2867-2269, Voisey, Alexander Christopher ORCID: https://orcid.org/0000-0001-6906-9397, Boest Bjerg, Kathrine, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2021. Circadian rhythm modulation of microbes during health and infection. Frontiers in Microbiology 12 , 721004. 10.3389/fmicb.2021.721004
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Huang, Juan, Tan, Qiyuan, Tai, Ningwen, Pearson, James Alexander ORCID: https://orcid.org/0000-0002-2867-2269, Li, Yangyang, Chao, Chen, Zhang, Lucy, Peng, Jian, Xing, Yanpeng, Zhang, Luyao, Hu, Youjia, Zhou, Zhiguang, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2021. IL-10 deficiency accelerates type 1 diabetes development via modulation of innate and adaptive immune cells and gut microbiota in BDC2.5 NOD mice. Frontiers in Immunology 12 , 702955. 10.3389/fimmu.2021.702955
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Pearson, James Alexander ORCID: https://orcid.org/0000-0002-2867-2269, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2021. Inflammasomes and type 1 diabetes. Frontiers in Immunology 12 , 686956. 10.3389/fimmu.2021.686956
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Siah, Q. Z., Ubeysekara, N. H., Taylor, P. N. ORCID: https://orcid.org/0000-0002-3436-422X, Davies, S. J., Wong, F.S. ORCID: https://orcid.org/0000-0002-2812-8845, Dayan, C. M. ORCID: https://orcid.org/0000-0002-6557-3462 and Alhadj Ali, M. ORCID: https://orcid.org/0000-0002-9780-6443 2021. Referral rates of patients with diabetes to secondary care are inversely related to the prevalence of diabetes in each primary care practice and confidence in treatment, not to HbA1c level. Primary Care Diabetes 15 (3) , pp. 513-517. 10.1016/j.pcd.2021.02.004
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Battaglia, M., Buckner, J. H., Levings, M. K., Richardson, S. J., Wong, F. S. ORCID: https://orcid.org/0000-0002-2812-8845 and Tree, T. I. 2021. Identifying the ‘Achilles heel’ of type 1 diabetes. Clinical and Experimental Immunology 204 (2) , pp. 167-178. 10.1111/cei.13570

Wong, F. S. ORCID: https://orcid.org/0000-0002-2812-8845 and Tree, T. I. 2021. Historical and new insights into pathogenesis of type 1 diabetes (2). Clinical and Experimental Immunology 204 (2) , pp. 165-166. 10.1111/cei.13597
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Boldison, Joanne, Thayer, Terri C., Davies, Joanne and Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 2021. Natural protection from Type 1 Diabetes in Non obese diabetic (Nod) mice is characterised by a unique pancreatic islet phenotype. Diabetes 70 (3) , db200945. 10.2337/db20-0945
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Thayer, Terri C., Davies, Joanne, Pearson, James A. ORCID: https://orcid.org/0000-0002-2867-2269, Hanna, Stephanie J., Wen, Li and Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 2021. Differentiating MHC-dependent and -independent mechanisms of lymph node stromal cell regulation of Proinsulin-specific CD8+ T-Cells in type 1 diabetes. Diabetes 70 (2) , pp. 529-537. 10.2337/db19-1050

Singh, Ravinder K., Malosse, Camille, Davies, Joanne, Malissen, Bernard, Kochba, Efrat, Levin, Yotam, Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924, Coulman, Sion A ORCID: https://orcid.org/0000-0002-1277-7584, Mous, Jan, McAteer, Martina A., Dayan, Colin M. ORCID: https://orcid.org/0000-0002-6557-3462, Henri, Sandrine and Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 2021. Using gold nanoparticles for enhanced intradermal delivery of poorly soluble auto-antigenic peptides. Nanomedicine: Nanotechnology, Biology and Medicine 32 , 102321. 10.1016/j.nano.2020.102321
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Huang, Juan, Peng, Jian, Pearson, James Alexander ORCID: https://orcid.org/0000-0002-2867-2269, Efthimiou, Georgios, Hu, Youjia, Tai, Ningwen, Xing, Yanpeng, Zhang, Luyao, Gu, Jianlei, Jiang, Jianping, Zhao, Hongyu, Zhou, Zhiguang, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2021. Toll-like receptor 7 deficiency suppresses type 1 diabetes development by modulating B-cell differentiation and function. Cellular and Molecular Immunology 18 , pp. 328-338. 10.1038/s41423-020-00590-8
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Sha, Sha, Pearson, James A ORCID: https://orcid.org/0000-0002-2867-2269, Peng, Jian, Hu, Youjia, Huang, Juan, Xing, Yanpeng, Zhang, Luyao, Zhu, Ying, Zhao, Hongyu, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Chen, Li and Wen, Li 2021. TLR9-deficiency in B cells promotes immune tolerance via IL-10 in a type 1 diabetes mouse model. Diabetes 70 (2) , pp. 504-515. 10.2337/db20-0373
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Boldison, Joanne, Da Rosa, Larissa Camargo and Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 2021. Regulatory B cells in type 1 diabetes. Mion, Francesca and Tonon, Silvia, eds. Regulatory B Cells, Vol. 2270. Methods in Molecular Biology, New York, US: Humana Press, pp. 419-435. (10.1007/978-1-0716-1237-8_22)

Pearson, James Alexander ORCID: https://orcid.org/0000-0002-2867-2269, Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2020. Crosstalk between circadian rhythms and the microbiota. Immunology 161 (4) , pp. 278-290. 10.1111/imm.13278
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Pearson, James A. ORCID: https://orcid.org/0000-0002-2867-2269, Li, Yangyang, Majewska-Szczepanik, Monika, Guo, Junhua, Zhang, Li, Liu, Yu, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2020. Insulin-reactive T cells convert diabetogenic insulin-reactive VH125 B cells into tolerogenic cells by reducing germinal center T:B cell Interactions in NOD mice. Frontiers in Immunology 11 , 585886. 10.3389/fimmu.2020.585886
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Huang, Juan, Huang, Gan, Li, Xia, Hu, Fang, Xie, Zhiguo, Xiao, Yang, Luo, Shuoming, Chao, Chen, Guo, Keyu, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Zhou, Zhiguang and Wen, Li 2020. Altered systemic and intestinal IgA immune responses in individuals with type 1 diabetes. Journal of Clinical Endocrinology and Metabolism 105 (12) , dgaa590. 10.1210/clinem/dgaa590
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Boldison, Joanne, Camargo Da Rosa, Larissa, Davies, Joanne, Wen, Li and Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 2020. Dendritic cells license regulatory B cells to produce IL-10 and mediate suppression of antigen-specific CD8 T cells. Cellular and Molecular Immunology 17 , 843 - 855. 10.1038/s41423-019-0324-z
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Hanna, Stephanie J., Powell, Wendy E. ORCID: https://orcid.org/0000-0002-4670-1406, Long, Anna E., Robinson, Emma J. S., Davies, Joanne, Megson, Clare, Howell, Alexandra, Jones, Taz J., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Dayan, Colin M. ORCID: https://orcid.org/0000-0002-6557-3462, Williams, Alistair J. K., Gillespie, Kathleen M. and Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 2020. Slow progressors to type 1 diabetes lose islet autoantibodies over time, have few islet antigen-specific CD8+ T cells and exhibit a distinct CD95hi B cell phenotype. Diabetologia 63 , pp. 1174-1185. 10.1007/s00125-020-05114-7
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Arikat, Farah ORCID: https://orcid.org/0000-0001-5300-6009, Hanna, Stephanie J., Singh, Ravinder K., Vilela, Luciano, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Dayan, Colin M. ORCID: https://orcid.org/0000-0002-6557-3462, Coulman, Sion A. ORCID: https://orcid.org/0000-0002-1277-7584 and Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924 2020. Targeting proinsulin to local immune cells using an intradermal microneedle delivery system; a potential antigen-specific immunotherapy for type 1 diabetes. Journal of Controlled Release 322 , pp. 593-601. 10.1016/j.jconrel.2020.02.031
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Huang, Juan, Pearson, James A. ORCID: https://orcid.org/0000-0002-2867-2269, Peng, Jian, Hu, Youjia, Sha, Sha, Xing, Yanpeng, Huang, Gan, Li, Xia, Hu, Fang, Xie, Zhiguo, Xiao, Yang, Luo, Shuoming, Chao, Chen, Wong, Florence S. ORCID: https://orcid.org/0000-0002-2812-8845, Zhou, Zhiguang and Wen, Li 2020. Gut microbial metabolites alter IgA immunity in type 1 diabetes. JCI Insight 5 (10) , e135718. 10.1172/jci.insight.135718
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Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2020. A predictive CD8+ T cell phenotype for T1DM progression. Nature Reviews Endocrinology 16 , pp. 198-199. 10.1038/s41574-020-0330-3
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Thayer, Terri C., Kakabadse, Dimitri, Boldison, Joanne and Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 2020. Assessing immune responses in the nonobese diabetic mouse model of type 1 Diabetes. Animal Models of Diabetes, Vol. 2128. Methods in Molecular Biology, New York, NY, USA: Humana Press, pp. 269-289. (10.1007/978-1-0716-0385-7_18)

Chen, Dawei, Thayer, Terri C., Wen, Li and Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 2020. Mouse models of autoimmune diabetes: the nonobese diabetic (NOD) mouse. Animal Models of Diabetes, Vol. 2128. Methods in Molecular Biology, New York, NY, USA: Humana Press, pp. 87-92. (10.1007/978-1-0716-0385-7_6)

Wong, F. S. ORCID: https://orcid.org/0000-0002-2812-8845 and Tree, T. I. 2019. Historical and new insights into pathogenesis of type 1 diabetes. Clinical and Experimental Immunology 198 (3) , pp. 292-293. 10.1111/cei.13396
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Boldison, Joanne, Da Rosa, Larissa C., Buckingham, Lucy, Davies, Joanne, Wen, Li and Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 2019. Phenotypically distinct anti-insulin B cells repopulate pancreatic islets after anti-CD20 treatment in NOD mice. Diabetologia 62 (11) , pp. 2052-2065. 10.1007/s00125-019-04974-y
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Pearson, James A. ORCID: https://orcid.org/0000-0002-2867-2269, Tai, Ningwen, Ekanayake-Alper, Dilrukshi K., Peng, Jian, Hu, Youjia, Hager, Karl, Compton, Susan, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Smith, Peter C. and Wen, Li 2019. Norovirus changes susceptibility to type 1 diabetes by altering intestinal microbiota and immune cell functions. Frontiers in Immunology 10 , 2654. 10.3389/fimmu.2019.02654
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Choudhury, M., Taylor, P. ORCID: https://orcid.org/0000-0002-3436-422X, Morgan, P. H. ORCID: https://orcid.org/0000-0002-8555-3493, Duckers, J., Lau, D., George, L., Ketchell, R. I. and Wong, F. S. ORCID: https://orcid.org/0000-0002-2812-8845 2019. Association between HbA1c and the development of cystic fibrosis‐related diabetes. Diabetic Medicine 36 (10) , pp. 1251-1255. 10.1111/dme.13912
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Powell, W.E. ORCID: https://orcid.org/0000-0002-4670-1406, Hanna, S.J., Hocter, C.N., Robinson, E., Lewis, M., Dunseath, G., Luzio, S., Howell, A., Dayan, C.M. ORCID: https://orcid.org/0000-0002-6557-3462 and Wong, F.S. ORCID: https://orcid.org/0000-0002-2812-8845 2019. Detecting autoreactive B cells in the peripheral blood of people with type 1 diabetes using ELISpot. Journal of Immunological Methods 471 , pp. 61-65. 10.1016/j.jim.2019.05.007
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Pearson, James A. ORCID: https://orcid.org/0000-0002-2867-2269, Kakabadse, Dimitri, Davies, Joanne, Peng, Jian, Warden-Smith, Jeremy, Cuff, Simone, Lewis, Mark, Camargo da Rosa, Larissa, Wen, Li and Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 2019. Altered gut microbiota activate and expand insulin B15-23-Reactive CD8+ T-Cells. Diabetes 68 (5) , pp. 1002-1013. 10.2337/db18-0487
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Dul, M. ORCID: https://orcid.org/0000-0002-0192-2280, Nikolic, T., Stefanidou, M., McAteer, M.A., Williams, P., Mous, J., Roep, B.O., Kochba, E., Levin, Y., Peakman, M., Wong, F.S. ORCID: https://orcid.org/0000-0002-2812-8845, Dayan, C.M. ORCID: https://orcid.org/0000-0002-6557-3462, Tatovic, D. ORCID: https://orcid.org/0000-0002-3879-2686, Coulman, S.A. ORCID: https://orcid.org/0000-0002-1277-7584 and Birchall, J.C. ORCID: https://orcid.org/0000-0001-8521-6924 2019. Conjugation of a peptide autoantigen to gold nanoparticles for intradermally administered antigen specific immunotherapy. International Journal of Pharmaceutics 562 , pp. 303-312. 10.1016/j.ijpharm.2019.03.041
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Liu, Mengju, Peng, Jian, Tai, Ningwen, Pearson, James A. ORCID: https://orcid.org/0000-0002-2867-2269, Hu, Changyun, Guo, Junhua, Hou, Lin, Zhao, Hongyu, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2018. Toll-like receptor 9 negatively regulates pancreatic islet beta cell growth and function in a mouse model of type 1 diabetes. Diabetologia 61 (11) , pp. 2333-2343. 10.1007/s00125-018-4705-0
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Hu, Youjia, Peng, Jian, Li, Fangyong, Wong, Florence ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2018. Evaluation of different mucosal microbiota leads to gut microbiota-based prediction of type 1 diabetes in NOD mice. Scientific Reports 8 10.1038/s41598-018-33571-z
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Szczepanik, Marian, Majewska-Szczepanik, Monika, Wong, Florence S. ORCID: https://orcid.org/0000-0002-2812-8845, Kowalczyk, Paulina, Pasare, Chandrashekhar and Wen, Li 2018. Regulation of contact sensitivity in non-obese diabetic (NOD) mice by innate immunity. Contact Dermatitis 79 (4) , p. 197. 10.1111/cod.13046
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Pearson, James A. ORCID: https://orcid.org/0000-0002-2867-2269, Agriantonis, Andrew, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2018. Modulation of the immune system by the gut microbiota in the development of type 1 diabetes. Human Vaccines and Immunotherapeutics 14 (11) , pp. 2580-2596. 10.1080/21645515.2018.1514354
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Gülden, Elke, Chao, Chen, Tai, Ningwen, Pearson, James A. ORCID: https://orcid.org/0000-0002-2867-2269, Peng, Jian, Majewska-Szczepanik, Monika, Zhou, Zhiguang, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2018. TRIF deficiency protects non-obese diabetic mice from type 1 diabetes by modulating the gut microbiota and dendritic cells. Journal of Autoimmunity 93 , pp. 57-65. 10.1016/j.jaut.2018.06.003
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Powell, Wendy E. ORCID: https://orcid.org/0000-0002-4670-1406, Hanna, Stephanie J., Hocter, Claire N., Robinson, Emma, Davies, Joanne, Dunseath, Gareth J., Luzio, Stephen, Farewell, Daniel ORCID: https://orcid.org/0000-0002-8871-1653, Wen, Li, Dayan, Colin M. ORCID: https://orcid.org/0000-0002-6557-3462, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938 and Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 2018. Loss of CXCR3 expression on memory B cells in individuals with long-standing type 1 diabetes. Diabetologia 61 , pp. 1794-1803. 10.1007/s00125-018-4651-x
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Long, Anna E., Wilson, Isabel V., Becker, Dorothy J., Libman, Ingrid M., Arena, Vincent C., Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845, Steck, Andrea K., Rewers, Marian J., Yu, Liping, Achenbach, Peter, Casas, Rosaura, Ludvigsson, Johnny, Williams, Alistair J. K. and Gillespie, Kathleen M. 2018. Characteristics of slow progression to diabetes in multiple islet autoantibody-positive individuals from five longitudinal cohorts: the SNAIL study. Diabetologia 61 (6) , pp. 1484-1490. 10.1007/s00125-018-4591-5
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Da Rosa, Larissa C., Boldison, Joanne, De Leenheer, Evy, Davies, Joanne, Wen, Li and Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 2018. B cell depletion reduces T cell activation in pancreatic islets in a murine autoimmune diabetes model. Diabetologia 61 (6) , pp. 1397-1410. 10.1007/s00125-018-4597-z
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James, Eddie A., Abreu, Joana R. F., McGinty, John W., Odegard, Jared M., Fillié, Yvonne E., Hocter, Claire N., Culina, Slobodan, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Alkanani, Aimon, Rihanek, Marynette, Fitzgerald-Miller, Lisa, Skowera, Ania, Speake, Cate, Gottlieb, Peter, Davidson, Howard W., Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Roep, Bart and Mallone, Roberto 2018. Combinatorial detection of autoreactive CD8+ T cells with HLA-A2 multimers: a multi-centre study by the Immunology of Diabetes Society T Cell Workshop. Diabetologia 61 (3) , pp. 658-670. 10.1007/s00125-017-4508-8
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Tan, Qiyuan, Tai, Ningwen, Li, Yangyang, Pearson, James ORCID: https://orcid.org/0000-0002-2867-2269, Pennetti, Sean, Zhou, Zhiguang, Wong, Florence ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2018. Activation-induced cytidine deaminase deficiency accelerates autoimmune diabetes in NOD mice. JCI Insight 3 (1) , 95882. 10.1172/jci.insight.95882
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Dul, M. ORCID: https://orcid.org/0000-0002-0192-2280, Stefanidou, M.., Porta, P., Serve, J., O'Mahony, C., Malissen, B., Henri, S., Levin, Y., Kochba, E., Wong, F.S. ORCID: https://orcid.org/0000-0002-2812-8845, Dayan, C. ORCID: https://orcid.org/0000-0002-6557-3462, Coulman, S.A. ORCID: https://orcid.org/0000-0002-1277-7584 and Birchall, J.C. ORCID: https://orcid.org/0000-0001-8521-6924 2017. Hydrodynamic gene delivery in human skin using a hollow microneedle device. Journal of Controlled Release 265 , pp. 120-131. 10.1016/j.jconrel.2017.02.028
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Zhao, Xin, Coulman, Sion A. ORCID: https://orcid.org/0000-0002-1277-7584, Hanna, Stephanie J., Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Dayan, Colin M. ORCID: https://orcid.org/0000-0002-6557-3462 and Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924 2017. Formulation of hydrophobic peptides for skin delivery via coated microneedles. Journal of Controlled Release 265 , pp. 2-13. 10.1016/j.jconrel.2017.03.015
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Reeves, Peta LS, Rudraraju, Rajeev, Liu, Xiao, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Hamilton-Williams, Emma E and Steptoe, Raymond J 2017. APC-targeted proinsulin expression inactivates insulin-specific memory CD8+ T cells in NOD mice. Immunology and Cell Biology 95 (9) , pp. 765-774. 10.1038/icb.2017.48
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Reeves, P.L.S., Rudraraju, R., Wong, Florence ORCID: https://orcid.org/0000-0002-2812-8845, Hamilton-Williams, E.E. and Steptoe, R.J. 2017. Antigen presenting cell-targeted proinsulin expression converts insulin-specific CD8(+) T-cell priming to tolerance in autoimmune-prone NOD mice. European Journal of Immunology 47 (9) , pp. 1550-1561. 10.1002/eji.201747089

Recino, Asha, Barkan, Kerry, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Ladds, Graham, Cooke, Anne and Wallberg, Maja 2017. Hyperglycaemia does not affect antigen-specific activation and cytolytic killing by CD8+ T cells in vivo. Bioscience Reports 37 (4) , 1079. 10.1042/BSR20171079
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Alhadj Ali, Mohammad ORCID: https://orcid.org/0000-0002-9780-6443, Liu, Yuk-Fun, Arif, Sefina, Tatovic, Danijela, Shariff, Hina, Gibson, Vivienne B., Yusuf, Norkhairin, Baptista, Roman, Eichmann, Martin, Petrov, Nedyalko, Heck, Susanne, Yang, Jennie H.M., Tree, Timothy I.M., Pujol-Autonell, Irma, Yeo, Lorraine, Baumard, Lucas R., Stenson, Rachel, Howell, Alex, Clark, Alison, Boult, Zoe, Powrie, Jake, Adams, Laura, Wong, Florence S. ORCID: https://orcid.org/0000-0002-2812-8845, Luzio, Stephen, Dunseath, Gareth, Green, Kate, O'Keefe, Alison, Bayly, Graham, Thorogood, Natasha, Andrews, Robert, Leech, Nicola, Joseph, Frank, Nair, Sunil, Seal, Susan, Cheung, HoYee, Beam, Craig, Hills, Robert, Peakman, Mark and Dayan, Colin M. ORCID: https://orcid.org/0000-0002-6557-3462 2017. Metabolic and immune effects of immunotherapy with proinsulin peptide in human new-onset type 1 diabetes. Science Translational Medicine 9 (402) , eaaf7779. 10.1126/scitranslmed.aaf7779
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Li, Y. Y., Pearson, J. A. ORCID: https://orcid.org/0000-0002-2867-2269, Chao, C., Peng, J., Zhang, X., Zhou, Z., Liu, Y., Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, L. 2017. Nucleotide-binding oligomerization domain-containing protein 2 (Nod2) modulates T1DM susceptibility by gut microbiota. Journal of Autoimmunity 82 , pp. 85-95. 10.1016/j.jaut.2017.05.007
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Wen, L and Wong, FS ORCID: https://orcid.org/0000-0002-2812-8845 2017. Dietary short chain fatty acids protect against type 1 diabetes. Nature Immunology 18 (5) , pp. 484-486. 10.1038/ni.3730
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Wallberg, Maja, Recino, Asha, Phillips, Jenny, Howie, Duncan, Vienne, Margaux, Paluch, Christopher, Azuma, Miyuki, Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845, Waldmann, Herman and Cooke, Anne 2017. Anti-CD3 treatment up-regulates programmed cell death protein-1 expression on activated effector T cells and severely impairs their inflammatory capacity. Immunology 151 (2) , pp. 248-260. 10.1111/imm.12729
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Fishman, Sigal, Lewis, Mark D., Siew, L. Khai, De Leenheer, Evy, Kakabadse, Dimitri, Davies, Joanne, Ziv, Doron, Margalit, Alon, Karin, Nathan, Gross, Gideon and Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 2017. Adoptive transfer of mRNA-Transfected T cells redirected against diabetogenic CD8 T cells can prevent diabetes. Molecular Therapy 25 (2) , pp. 456-464. 10.1016/j.ymthe.2016.12.007
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Hu, Youjia, Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2017. Antibiotics, gut microbiota, environment in early life and type 1 diabetes. Pharmacological Research 119 , pp. 219-226. 10.1016/j.phrs.2017.01.034
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Boldison, Joanne and Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 2016. Immune and pancreatic β cell interactions in type 1 diabetes. Trends in Endocrinology & Metabolism 27 (12) , pp. 856-867. 10.1016/j.tem.2016.08.007
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Williams, Georgina M., Long, Anna E., Wilson, Isabel V., Aitken, Rachel J., Wyatt, Rebecca C., McDonald, Timothy J., Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845, Hattersley, Andrew T., Williams, Alistair J. K., Bingley, Polly J. and Gillespie, Kathleen M. 2016. Beta cell function and ongoing autoimmunity in long-standing, childhood onset type 1 diabetes. Diabetologia 59 (12) , pp. 2722-2726. 10.1007/s00125-016-4087-0
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Thayer, Terri C., Pearson, James A. ORCID: https://orcid.org/0000-0002-2867-2269, De Leenheer, Evy, Hanna, Stephanie J., Boldison, Joanne, Davies, Joanne ORCID: https://orcid.org/0000-0002-7369-6032, Tsui, Adrian, Ahmed, Sartaj, Easton, Peter, Siew, Lai Khai, Wen, Li and Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 2016. Peripheral proinsulin expression controls low-avidity proinsulin-reactive CD8 T Cells in type 1 diabetes. Diabetes 65 (11) , pp. 3429-3439. 10.2337/db15-1649
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Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Pearson, James ORCID: https://orcid.org/0000-0002-2867-2269, Gras, Stephanie, Van den berg, Hugo, Lissina, Anya, Llewellyn-Lacey, Sian, Willis, Mark ORCID: https://orcid.org/0000-0003-3024-6063, Dockree, Tamsin, McLaren, James ORCID: https://orcid.org/0000-0002-7021-5934, Ekeruche-Makinde, Julia, Gostick, Emma, Robertson, Neil ORCID: https://orcid.org/0000-0002-5409-4909, Burrows, Scott, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Peakman, Mark, Skowera, Ania and Wooldridge, Linda 2016. Targeted suppression of autoreactive CD8+ T-cell activation using blocking anti-CD8 antibodies. Scientific Reports 6 , 35332. 10.1038/srep35332
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Tai, Ningwen, Peng, Jian, Liu, Fuqiang, Gulden, Elke, Hu, Youjia, Zhang, Xiaojun, Chen, Li, Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2016. Microbial antigen mimics activate diabetogenic CD8 T cells in NOD mice. Journal of Experimental Medicine 213 (10) , p. 2129. 10.1084/jem.20160526
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Hu, Youjia, Jin, Ping, Peng, Jian, Zhang, Xiaojun, Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2016. Different immunological responses to early-life antibiotic exposure affecting autoimmune diabetes development in NOD mice. Journal of Autoimmunity 72 , pp. 47-56. 10.1016/j.jaut.2016.05.001
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Tai, Ningwen, Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2016. The role of the innate immune system in destruction of pancreatic beta cells in NOD mice and humans with type I diabetes. Journal of Autoimmunity 71 , pp. 26-34. 10.1016/j.jaut.2016.03.006

Thayer, Terri C. and Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 2016. Tracking immunological responses of Islet antigen-specific T cells in the Nonobese Diabetic (NOD) Mouse Model of Type 1 Diabetes. Gillespie, K.M., ed. Type-1 Diabetes: Methods and Protocols, Vol. 1433. Methods in Molecular Biology, Humana Press, New York, NY, pp. 127-134. (10.1007/7651_2015_293)

De Leenheer, Evy and Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 2016. Adoptive transfer of autoimmune diabetes using immunodeficient Non Obese Diabetic (NOD) mice. Gillespie, Kathleen M., ed. Type-1 Diabetes: Methods and Protocols, Vol. 1433. Methods in Molecular Biology, Humana Press, New York, NY, pp. 135-140. (10.1007/7651_2015_294)

Pearson, James A. ORCID: https://orcid.org/0000-0002-2867-2269, Thayer, Terri C., McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, De Leenheer, Evy, Phillips, Amy, Davies, Joanne, Kakabadse, Dimitri, Miners, Kelly, Morgan, Peter ORCID: https://orcid.org/0000-0002-8555-3493, Wen, Li, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 2016. Proinsulin expression shapes the TCR repertoire but fails to control the development of low-avidity insulin-reactive CD8+ T cells. Diabetes 65 (6) , pp. 1679-1689. 10.2337/db15-1498
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Peng, Jian, Hu, Youjia, Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2016. The gut microbiome in the NOD mouse. Gillespie, Kathleen M., ed. Type-1 Diabetes: Methods and Protocols, Vol. 1433. Methods in Molecular Biology, vol. 1433. Springer, pp. 169-177. (10.1007/7651_2016_331)

Zhao, Xin, Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924, Coulman, Sion A. ORCID: https://orcid.org/0000-0002-1277-7584, Tatovic, Danijela ORCID: https://orcid.org/0000-0002-3879-2686, Singh, Ravinder K., Wen, Li, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Dayan, Colin M. ORCID: https://orcid.org/0000-0002-6557-3462 and Hanna, Stephanie J. 2016. Microneedle delivery of autoantigen for immunotherapy in type 1 diabetes. Journal of Controlled Release 223 , pp. 178-187. 10.1016/j.jconrel.2015.12.040
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Pearson, James A. ORCID: https://orcid.org/0000-0002-2867-2269, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2016. The importance of the Non Obese Diabetic (NOD) mouse model in autoimmune diabetes. Journal of Autoimmunity 66 , pp. 76-88. 10.1016/j.jaut.2015.08.019

Barbera Betancourt, Ariana, Emery, Juliet L., Recino, Asha, Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845, Cooke, Anne, Okkenhaug, Klaus and Wallberg, Maja 2016. Inhibition of phosphoinositide 3-Kinase p110delta does not affect T cell driven development of Type 1 diabetes despite significant effects on cytokine production. PLoS ONE 11 (1) , e0146516. 10.1371/journal.pone.0146516
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Pearson, James A. ORCID: https://orcid.org/0000-0002-2867-2269 and Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 2015. Identification of islet antigen-specific CD8 T cells using MHCI-peptide tetramer reagents in the non obese diabetic (NOD) mouse model of type 1 diabetes. Gillespie, Kathleen M., ed. Type-1 Diabetes, Vol. 1433. Methods in Molecular Biology, Springer, pp. 119-125. (10.1007/7651_2015_295)

Alhadj Ali, Mohammad ORCID: https://orcid.org/0000-0002-9780-6443, Thrower, Sally L., Hanna, Stephanie J., Coulman, Sion A. ORCID: https://orcid.org/0000-0002-1277-7584, Birchall, James C. ORCID: https://orcid.org/0000-0001-8521-6924, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Dayan, Colin Mark ORCID: https://orcid.org/0000-0002-6557-3462 and Tatovic, Danijela ORCID: https://orcid.org/0000-0002-3879-2686 2015. Topical steroid therapy induces pro-tolerogenic changes in Langerhans cells in human skin. Immunology 146 (3) , pp. 411-422. 10.1111/imm.12518
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Hu, Youjia, Peng, Jian, Tai, Ningwen, Hu, Changyun, Zhang, Xiaojun, Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2015. Maternal antibiotic treatment protects offspring from diabetes development in nonobese diabetic mice by generation of tolerogenic APCs. Journal of Immunology 195 (9) , pp. 4176-4184. 10.4049/jimmunol.1500884

Culina, Slobodan, Gupta, Nimesh, Boisgard, Raphael, Afonso, Georgia, Gagnerault, Marie-Claude, Dimitrov, Jordan, Østerbye, Thomas, Justesen, Sune, Luce, Sandrine, Attias, Mikhaël, Kyewski, Bruno, Buus, Søren, Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845, Lacroix-Desmazes, Sebastien and Mallone, Roberto 2015. Materno-Fetal transfer of preproinsulin through the neonatal FC receptor prevents autoimmune diabetes. Diabetes 64 (10) , pp. 3532-3542. 10.2337/db15-0024

Hu, Changyun, Ding, Heyuan, Li, Yangyang, Pearson, James A. ORCID: https://orcid.org/0000-0002-2867-2269, Zhang, Xiaojun, Flavell, Richard A., Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2015. NLRP3 deficiency protects from type 1 diabetes through the regulation of chemotaxis into the pancreatic islets. Proceedings of the National Academy of Sciences 112 (36) , pp. 11318-11323. 10.1073/pnas.1513509112

Gülden, Elke, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2015. The gut microbiota and Type 1 Diabetes. Clinical Immunology 159 (2) , pp. 143-153. 10.1016/j.clim.2015.05.013

Motozono, Chihiro, Pearson, James A. ORCID: https://orcid.org/0000-0002-2867-2269, De Leenheer, Evy, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Trimby, Andrew, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396 2015. Distortion of the major histocompatibility complex class I binding groove to accommodate an insulin-derived 10-Mer peptide. Journal of Biological Chemistry 290 (31) , pp. 18924-18933. 10.1074/jbc.M114.622522
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Tatovic, Danijela ORCID: https://orcid.org/0000-0002-3879-2686, Young, Philippa, Kochba, Efrat, Levin, Yotam, Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Dayan, Colin Mark ORCID: https://orcid.org/0000-0002-6557-3462 2015. Fine-needle aspiration biopsy of the lymph node: a novel tool for the monitoring of immune responses after skin antigen delivery. Journal of Immunology 195 (1) , pp. 386-392. 10.4049/jimmunol.1500364

Sayers, Adrian, Thayer, Daniel, Harvey, John N., Luzio, Stephen, Atkinson, Mark D., French, Robert, Warner, Justin T., Dayan, Colin M. ORCID: https://orcid.org/0000-0002-6557-3462, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Gregory, John W. ORCID: https://orcid.org/0000-0001-5189-3812 2015. Evidence for a persistent, major excess in all cause admissions to hospital in children with type-1 diabetes: results from a large Welsh national matched community cohort study. BMJ Open 5 , e005644. 10.1136/bmjopen-2014-005644
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Tai, Ningwen, Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2015. The role of gut microbiota in the development of type 1, type 2 diabetes mellitus and obesity. Reviews in Endocrine and Metabolic Disorders 16 (1) , pp. 55-65. 10.1007/s11154-015-9309-0

Lewis, Mark David, de Leenheer, Evy, Fishman, Sigal, Siew, Lai Khai, Gross, Gideon and Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 2015. A reproducible method for the expansion of mouse CD8+ T lymphocytes. Journal of Immunological Methods 417 , pp. 134-138. 10.1016/j.jim.2015.01.004
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Kleffel, Sonja, Vergani, Andrea, Tezza, Sara, Ben Nasr, Moufida, Niewczas, Monika A., Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845, Bassi, Roberto, D'Addio, Francesca, Schatton, Tobias, Abdi, Reza, Atkinson, Mark, Sayegh, Mohamed H., Wen, Li, Wasserfall, Clive H., O'Connor, Kevin C. and Fiorina, Paolo 2014. Interleukin-10+ regulatory B cells arise within antigen-experienced CD40+B cells to maintain tolerance to islet autoantigens. Diabetes 64 (1) , pp. 158-171. 10.2337/db13-1639

Pearson, James, Thayer, T. C., McLaren, James Edward ORCID: https://orcid.org/0000-0002-7021-5934, Miners, Kelly Louise, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Price, David ORCID: https://orcid.org/0000-0001-9416-2737 and Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 2014. Analysis of the repertoire of insulin-reactive CD8(+) T cells [Abstract]. Immunology 143 (S2) , p. 152. 10.1111/imm.12406

Perez, Shira, Fishman, Sigal, Bordowitz, Amos, Margalit, Alon, Wong, Florence ORCID: https://orcid.org/0000-0002-2812-8845 and Gross, Gideon 2014. Selective immunotargeting of diabetogenic CD4 T cells by genetically redirected T cells. Immunology 143 (4) , pp. 609-617. 10.1111/imm.12340

Yüksel, Muhammed, Laukens, Debby, Heindryckx, Femke, Van Vlierberghe, Hans, Geerts, Anja, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Wen, Li and Colle, Isabelle 2014. Hepatitis mouse models: from acute-to-chronic autoimmune hepatitis. International Journal of Experimental Pathology 95 (5) , pp. 309-320. 10.1111/iep.12090

Peng, Jian, Narasimhan, Sukanya, Marchesi, Julian Roberto ORCID: https://orcid.org/0000-0002-7994-5239, Benson, Andrew, Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2014. Long term effect of gut microbiota transfer on diabetes development. Journal of Autoimmunity 53 , pp. 85-94. 10.1016/j.jaut.2014.03.005

Tan, Q., Majewska-Szczepanik, M., Zhang, X., Szczepanik, M., Zhou, Z., Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, L. 2014. IRAK-M deficiency promotes the development of type 1 diabetes in NOD mice. Diabetes 63 (8) , pp. 2761-2775. 10.2337/db13-1504

Hsu, Hsiang-Ting, Janssen, Linda, Lawand, Myriam, Kim, Jessica, Perez-Arroyo, Alicia, Culina, Slobodan, Gdoura, Abdel, Burgevin, Anne, Cumenal, Delphine, Fourneau, Yousra, Moser, Anna, Kratzer, Roland, Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845, Springer, Sebastian and van Endert, Peter 2014. Endoplasmic reticulum targeting alters regulation of expression and antigen presentation of proinsulin. The Journal of Immunology 192 (11) , pp. 4957-4966. 10.4049/jimmunol.1300631

Wong, Florence ORCID: https://orcid.org/0000-0002-2812-8845 2014. How does B-Cell tolerance contribute to the protective effects of diabetes following induced mixed chimerism in autoimmune diabetes? Diabetes 63 (6) , pp. 1855-1857. 10.2337/db14-0327

Thomas, D. C., Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Zaccone, P., Green, E. A. and Wallberg, M. 2013. Protection of Islet Grafts through transforming growth factor-β–induced Tolerogenic Dendritic cells. Diabetes 62 (9) , pp. 3132-3142. 10.2337/db12-1740

Tai, N., Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, L. 2013. TLR9 deficiency promotes CD73 expression in T cells and diabetes protection in nonobese diabetic mice. The Journal of Immunology 191 (6) , pp. 2926-2937. 10.4049/jimmunol.1300547

Hu, C, Ding, H, Zhang, X, Wong, Florence ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, L 2013. Combination treatment with Anti-CD20 and oral Anti-CD3 prevents and reverses autoimmune diabetes. Diabetes 62 (8) , pp. 2849-2858. 10.2337/db12-1175

Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2013. Therapy: Immunotherapy for T1DM—targeting innate immunity. Nature Reviews Endocrinology 9 (7) , pp. 384-385. 10.1038/nrendo.2013.103

Alhadj Ali, Mohammad ORCID: https://orcid.org/0000-0002-9780-6443, Hanna, Stephanie, Wong, Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Dayan, Colin ORCID: https://orcid.org/0000-0002-6557-3462 2012. Functional modulation of epidermal dendritic cells by topical steroid treatment to optimise the tolerogenic potential of immunotherapy for type 1 diabetes [Abstract]. Diabetologia 55 (S1) , S192. 10.1007/s00125-012-2688-9

Dong, Baojun, Qi, Dake, Yang, Long, Huang, Yan, Xiao, Xiaoyan, Tai, Ningwen, Wen, Li and Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 2012. TLR4 regulates cardiac lipid accumulation and diabetic heart disease in the nonobese diabetic mouse model of type 1 diabetes. American Journal of Physiology - Heart and Circulatory Physiology 303 (6) , H732-H742. 10.1152/ajpheart.00948.2011

Xiang, Yufei, Peng, Jian, Tai, Ningwen, Hu, Changyun, Zhou, Zhiguang, Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2012. The dual effects of B cell depletion on antigen-specific T cells in BDC2.5NOD mice. The Journal of Immunology 188 (10) , pp. 4747-4758. 10.4049/jimmunol.1103055

Hu, Changyun, Du, Wei, Zhang, Xiaojun, Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2012. The role of Gr1+ cells after anti-CD20 treatment in type 1 diabetes in nonobese diabetic mice. The Journal of Immunology 188 (1) , pp. 294-301. 10.4049/jimmunol.1101590

Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2012. Type 1 diabetes therapy beyond T cell targeting: Monocytes, B cells, and innate lymphocytes. The Review of Diabetic Studies 9 (4) , pp. 289-304. 10.1900/RDS.2012.9.289

Alhadj Ali, Mohammad ORCID: https://orcid.org/0000-0002-9780-6443, Thrower, Sally, Harris, Stephanie, Wong, Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Dayan, Colin ORCID: https://orcid.org/0000-0002-6557-3462 2011. Optimizing the tolerogenic potential of a 'vaccine' for type 1 diabetes by topical betamethasone therapy [Abstract]. Diabetologia 54 (S1) , S88-S89. 10.1007/s00125-011-2276-4

Tai, Ningwen, Yasuda, Hisafumi, Xiang, Yufei, Zhang, Li, Rodriguez-Pinto, Daniel, Yokono, Koichi, Sherwin, Robert, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Nagata, Masao and Wen, Li 2011. IL-10-conditioned dendritic cells prevent autoimmune diabetes in NOD and humanized HLA-DQ8/RIP-B7.1 mice. Clinical Immunology 139 (3) , pp. 336-349. 10.1016/j.clim.2011.03.003

Alhadj Ali, Mohammad ORCID: https://orcid.org/0000-0002-9780-6443, Thrower, Sally, Harris, Stephanie, Wong, Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Dayan, Colin ORCID: https://orcid.org/0000-0002-6557-3462 2011. Effects of topical steroid and vitamin D therapy in optimizing the tolerogenic potential of a 'vaccine' for type 1 diabetes. Diabetic Medicine 28 (S1) , p. 80. 10.1111/j.1464-5491.2011.03233_1.x

Wallberg, M., Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Green, E. A. 2011. An islet-specific pulse of TGF-abrogates CTL function and promotes cell survival independent of Foxp3+ T cells. Journal of Immunology 186 (4) , pp. 2543-2551. 10.4049/jimmunol.1002098

Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 2011. Stimulating IL-13 receptors on T cells: a new pathway for tolerance induction in diabetes? Diabetes 60 (6) , pp. 1657-1659. 10.2337/db11-0353

Oresic, Matej, Brezar, Vedran, Culina, Slobodan, Østerbye, Thomas, Guillonneau, François, Chiappetta, Giovanni, Verdier, Yann, Vinh, Joelle, Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845, Buus, Søren and Mallone, Roberto 2011. T cells recognizing a peptide contaminant undetectable by mass spectrometry. PLoS ONE 6 (12) , e28866. 10.1371/journal.pone.0028866
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Mallone, R., Scotto, M., Janicki, Claire Nicola, James, E. A., Fitzgerald-Miller, L., Wagner, R., Gottlieb, P., Thorpe, J, Jospe, N., Durinovic-Bellò, I., Boitard, C., Lou, O., Dayan, Colin Mark ORCID: https://orcid.org/0000-0002-6557-3462 and Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 2011. Immunology of diabetes society T-Cell workshop: HLA class I tetramer-directed epitope validation initiative T-Cell workshop report-HLA class I tetramer validation initiative. Diabetes/Metabolism Research and Reviews 27 (8) , pp. 720-726. 10.1002/dmrr.1243

Mehers, K. L., Long, A. E., Slik, A. R., Aitken, R. J., Nathwani, V., Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845, Bain, S., Gill, G., Roep, B. O., Bingley, P. J. and Gillespie, K. 2011. An increased frequency of NK cell receptor and HLA-C group 1 combinations in early-onset type 1 diabetes. Diabetologia 54 (12) , pp. 3062-3070. 10.1007/s00125-011-2299-x

Mallone, R., Mannering, S. I., Brooks-Worrell, B. M., Durinovic-Belló, I., Cilio, C. M., Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Schloot, N. C. 2011. Isolation and preservation of peripheral blood mononuclear cells for analysis of islet antigen-reactive T cell responses: position statement of the T-Cell Workshop Committee of the Immunology of Diabetes Society. Clinical and Experimental Immunology 163 (1) , pp. 33-49. 10.1111/j.1365-2249.2010.04272.x

Scott, Gwen S., Fishman, Sigal, Siew, Lai Khai, Margalit, Alon, Chapman, Stephen, Chervonsky, Alexander V., Wen, Li, Gross, Gideon and Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 2010. Immunotargeting of insulin reactive CD8 T cells to prevent diabetes. Journal of Autoimmunity 35 (4) , pp. 390-397. 10.1016/j.jaut.2010.08.005

Petrich de Marquesini, L. G., Fu, J., Connor, K. J., Bishop, Amanda J., McLintock, N. E., Pope, Charles A., Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Dayan, Colin Mark ORCID: https://orcid.org/0000-0002-6557-3462 2010. IFN-γ and IL-10 islet-antigen-specific T cell responses in autoantibody-negative first-degree relatives of patients with type 1 diabetes. Diabetologia 53 (7) , pp. 1451-1460. 10.1007/s00125-010-1739-3

Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845, Hu, Changyun, Xiang, Yufei and Wen, Li 2010. To B or not to B - pathogenic and regulatory B cells in autoimmune diabetes. Current Opinion in Immunology 22 (6) , pp. 723-731. 10.1016/j.coi.2010.10.002

Mannering, S. I., Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845, Durinovic-Belló, I., Brooks-Worrell, B., Tree, T. I., Cilio, C. M., Schloot, N. C. and Mallone, R. 2010. Current approaches to measuring human islet-antigen specific T cell function in type 1 diabetes. Clinical and Experimental Immunology 162 (2) , pp. 197-209. 10.1111/j.1365-2249.2010.04237.x

Sequeiros, I. M., Hester, K., Callaway, M., Williams, A., Garland, Z., Powell, Tom, Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Jarad, N. A. 2010. MRI appearance of the pancreas in patients with cystic fibrosis: A comparison of pancreas volume in diabetic and non-diabetic patients. British Journal of Radiology 83 (995) , pp. 921-926. 10.1259/bjr/24009651

Colonna, Lucrezia, Catalano, Geoffrey, Chew, Claude, D'Agati, Vivette, Thomas, James W., Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845, Schmitz, Jochen, Masuda, Esteban S., Reizis, Boris, Tarakhovsky, Alexander and Clynes, Raphael 2010. Therapeutic targeting of syk in autoimmune diabetes. The Journal of Immunology 185 (3) , pp. 1532-1543. 10.4049/jimmunol.1000983

Jarad, N. A., Sequeiros, I. M., Hester, K., Callaway, M., Williams, A. J., Sund, Z., Powell, Tom and Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 2010. The size of the spleen by magnetic resonance imaging in patients with cystic fibrosis; with and without diabetes--a novel observational study. QJM: An International Journal of Medicine 103 (4) , pp. 237-242. 10.1093/qjmed/hcp193

Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845, Siew, Lai Khai, Scott, Gwen, Thomas, Ian J., Chapman, Stephen, Viret, Christopher and Wen, Li 2009. Activation of insulin-reactive CD8 T-cells for development of autoimmune diabetes. Diabetes 58 (5) , pp. 1156-1164. 10.2337/db08-0800

Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2009. Innate immunity and autoimmune disease [Editorial]. Current Molecular Medicine 9 (1) , pp. 1-3. 10.2174/156652409787314462

Ferreira, Christina, Singh, Yogesh, Furmanski, Anna L., Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845, Garden, Oliver A. and Dyson, Julian 2009. Non-obese diabetic mice select a low-diversity repertoire of natural regulatory T cells. Proceedings of the National Academy of Sciences of the United States of America 106 (20) , pp. 8320-8325. 10.1073/pnas.0808493106

Xiao, Xiaoyan, Ma, Bin, Dong, Baojun, Zhao, Peng, Tai, Ningwen, Chen, Li, Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2009. Cellular and humoral immune responses in the early stages of diabetic nephropathy in NOD mice. Journal of Autoimmunity 32 (2) , pp. 85-93. 10.1016/j.jaut.2008.12.003

Thrower, S. L., James, L., Hall, W., Green, K. M., Arif, S., Allen, J. S., Van-Krinks, C., Lozanoska-Ochser, B., Marquesini, L., Brown, S., Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845, Dayan, Colin Mark ORCID: https://orcid.org/0000-0002-6557-3462 and Peakman, M. 2009. Proinsulin peptide immunotherapy in type 1 diabetes: report of a first-in-man Phase I safety study. Clinical and Experimental Immunology 155 (2) , pp. 156-165. 10.1111/j.1365-2249.2008.03814.x

Hu, C., Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, L. 2009. Translational Mini-Review Series on B Cell-Directed Therapies: B cell-directed therapy for autoimmune diseases. Clinical and Experimental Immunology 157 (2) , pp. 181-190. 10.1111/j.1365-2249.2009.03977.x

Xiao, Xiaoyan, Zhao, Peng, Rodriguez-Pinto, Daniel, Qi, Dake, Henegariu, Octavian, Alexopoulou, Lena, Flavell, Richard A., Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2009. Inflammatory regulation by TLR3 in acute hepatitis. The Journal of Immunology 183 (6) , pp. 3712-3719. 10.4049/jimmunol.0901221

Hu, Changyun, Deng, Songyan, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2008. Anti-CD20 treatment prolongs syngeneic Islet graft survival and delays the onset of recurrent autoimmune diabetes. Annals of the New York Academy of Sciences 1150 (1) , pp. 217-219. 10.1196/annals.1447.032

Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2008. IFN-α can both protect against and promote the development of Type 1 diabetes. Annals of the New York Academy of Sciences 1150 (1) , pp. 187-189. 10.1196/annals.1447.031

Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Hu, Changyun, Zhang, Li, Du, Wei, Alexopoulou, Lena, Flavell, Richard A. and Wen, Li 2008. The role of toll-like receptors 3 and 9 in the development of autoimmune diabetes in NOD mice. Annals of the New York Academy of Sciences 1150 (1) , pp. 146-148. 10.1196/annals.1447.039

Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Wen, Li 2008. Toll-like receptors and diabetes. Annals of the New York Academy of Sciences 1150 (1) , pp. 123-132. 10.1196/annals.1447.063

Scott, Gwen S., Fishman, Sigal, Margalit, Alon, Siew, L. Khai, Chapman, Stephen, Wen, Li, Gross, Gideon and Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 2008. Developing a novel model system to target insulin-reactive CD8 T cells. Annals of the New York Academy of Sciences 1150 (1) , pp. 54-58. 10.1196/annals.1447.040

Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Dayan, Colin M. 2008. Regulatory T cells in autoimmune endocrine diseases. Trends in Endocrinology & Metabolism 19 (8) , pp. 292-299. 10.1016/j.tem.2008.07.007

Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Siew, L. Khai and Wen, Li 2008. CD8+ T-cells and their interaction with other cells in damage to islet β-cells. Biochemical Society Transactions 36 (3) , pp. 316-320. 10.1042/BST0360316

Rutter, Guy A. and Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845 2008. The pancreatic β-cell: birth, life and death. Biochemical Society Transactions 36 (3) , pp. 267-271. 10.1042/BST0360267

Riboulet-Chavey, Audrey, Diraison, Frederique, Siew, Lai Khai, Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Rutter, Guy A. 2008. Inhibition of AMP-activated protein kinase protects pancreatic β-cells from cytokine-mediated apoptosis and CD8+ T-cell-induced cytotoxicity. Diabetes 57 (2) , pp. 415-423. 10.2337/db07-0993

Brodie, Gillian M., Wallberg, Maja, Santamaria, Pere, Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Green, E. Allison 2008. B-cells promote intra-islet CD8+ cytotoxic T-cell survival to enhance type 1 diabetes. Diabetes 57 (4) , pp. 909-917. 10.2337/db07-1256

Petrich de Marquesini, Liliana G., Moustakas, Antonis K., Thomas, Ian J., Wen, Li, Papadopoulos, George K. and Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 2008. Functional inhibition related to structure of a highly potent insulin-specific CD8 T cell clone using altered peptide ligands. European Journal of Immunology 38 (1) , pp. 240-249. 10.1002/eji.200737762

Baker, Caroline, Petrich de Marquesini, Liliana G., Bishop, Amanda J., Hedges, Alan J., Dayan, Colin Mark ORCID: https://orcid.org/0000-0002-6557-3462 and Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 2008. Human CD8 responses to a complete epitope set from preproinsulin: implications for approaches to epitope discovery. Journal of Clinical Immunology 28 (4) , pp. 350-360. 10.1007/s10875-008-9177-4

Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845 and Dayan, Colin Mark ORCID: https://orcid.org/0000-0002-6557-3462 2008. Regulatory T cells in autoimmune endocrine diseases. Trends in Endocrinology & Metabolism 19 (8) , pp. 292-299. 10.1016/j.tem.2008.07.007

Wen, Li, Ley, Ruth E., Volchkov, Pavel Yu., Stranges, Peter B., Avanesyan, Lia, Stonebraker, Austin C., Hu, Changyun, Wong, Florence Susan ORCID: https://orcid.org/0000-0002-2812-8845, Szot, Gregory L., Bluestone, Jeffrey A., Gordon, Jeffrey I. and Chervonsky, Alexander V. 2008. Innate immunity and intestinal microbiota in the development of Type 1 diabetes [Letter]. Nature 455 (7216) , pp. 1109-1113. 10.1038/nature07336

This list was generated on Sun Apr 14 04:36:40 2024 BST.