Browse by Current Cardiff authors

Mazzarino, Morgane, Cetin, Esra, Bartosova, Maria, Marinovic, Iva, Ipseiz, Natacha ORCID: https://orcid.org/0000-0001-5008-8889, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Schmitt, Claus Peter, Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578, Labéta, Mario O. ORCID: https://orcid.org/0000-0001-5750-6983 and Raby, Anne-Catherine ORCID: https://orcid.org/0000-0002-5354-5835 2023. Therapeutic targeting of chronic kidney disease-associated DAMPs differentially contributing to vascular pathology. Frontiers in Immunology 14 , 1240679. 10.3389/fimmu.2023.1240679

Chan, Yee-Hung, Moss, Joe W. E. ORCID: https://orcid.org/0000-0002-1866-9752, Williams, Jessica O., Ferekidis, Nele, Alshehri, Nouf, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Menendez Gonzalez, Juan B., Plummer, Sue F., Michael, Daryn R., Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733 and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2023. (+)-catechin attenuates multiple atherosclerosis-associated processes in vitro, modulates disease-associated risk factors in C57BL/6J mice and reduces atherogenesis in LDL receptor deficient mice by inhibiting inflammation and increasing markers of plaque stability. Molecular Nutrition & Food Research 67 (14) , 2200716. 10.1002/mnfr.202200716

Alalawi, Sulaiman, Albalawi, Faizah and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2023. The role of punicalagin and its metabolites in atherosclerosis and risk factors associated with the disease. International Journal of Molecular Sciences 24 (10) , 8476. 10.3390/ijms24108476

O'Morain, Victoria L., Chen, Jing, Plummer, Sue F., Michael, Daryn R. and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2023. Anti-Atherogenic actions of the Lab4b consortium of probiotics in vitro. International Journal of Molecular Sciences 24 (4) , 3639. 10.3390/ijms24043639

Takala, Rabaa, Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 and Choy, Ernest ORCID: https://orcid.org/0000-0003-4459-8609 2023. The beneficial effects of pine nuts and its major fatty acid, pinolenic acid, on inflammation and metabolic perturbations in inflammatory disorders. International Journal of Molecular Sciences 24 (2) , 1171. 10.3390/ijms24021171

Zabetakis, Ioannis, Lordan, Ronan, Tsoupras, Alexandros and Ramji, Dipak ORCID: https://orcid.org/0000-0002-6419-5578, eds. 2022. Functional foods and their implications for health promotion. Elsevier.

Takala, Rabaa, Ramji, Dipak ORCID: https://orcid.org/0000-0002-6419-5578, Andrews, Robert, Zhou, You ORCID: https://orcid.org/0000-0002-1743-1291, Farhat, Mustafa, Elmajee, Mohammed, Rundle, Shelley and Choy, Ernest ORCID: https://orcid.org/0000-0003-4459-8609 2022. Pinolenic acid exhibits Anti-inflammatory and Anti-atherogenic effects in Peripheral blood- derived Monocytes from patients with Rheumatoid Arthritis. Scientific Reports 12 , 8807. 10.1038/s41598-022-12763-8

Takala, Rabaa, Ramji, Dipak P ORCID: https://orcid.org/0000-0002-6419-5578, Andrews, Robert, Zhou, You ORCID: https://orcid.org/0000-0002-1743-1291, Burston, James and Choy, Ernest ORCID: https://orcid.org/0000-0003-4459-8609 2022. Anti-inflammatory and immunoregulatory effects of pinolenic acid in rheumatoid arthritis. Rheumatology 61 (3) , pp. 992-1004. 10.1093/rheumatology/keab467

Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578, ed. 2022. Atherosclerosis: Methods and protocols. Methods in Molecular Biology, New York: Humana Press. 10.1007/978-1-0716-1924-7

Chan, Yee-Hung, Alotibi, Reem, Alahmadi, Alaa and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2022. Monitoring cellularity and expression of key in atherosclerotic plaques. Ramji, Dipak, ed. Atherosclerosis: Methods and Protocols, Vol. 2419. Methods in Molecular Biology, Springer, pp. 497-506. (10.1007/978-1-0716-1924-7_30)

Chan, Yee-Hung, Alahmadi, Alaa, Alotibi, Reem and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2022. Evaluation of plaque burden and in atherosclerotic plaques. Ramji, Dipak, ed. Atherosclerosis: Methods and Protocols, Vol. 2419. Methods in Molecular Biology, Springer, pp. 481-496. (10.1007/978-1-0716-1924-7_29)

Chan, Yee-Hung and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2022. Probing inflammasome activation in atherosclerosis. Ramji, Dipak, ed. Atherosclerosis: Methods and Protocols, Vol. 2419. Methods in Molecular Biology, New York, NY: Springer, pp. 313-331. (10.1007/978-1-0716-1924-7_20)

Chan, Yee-Hung and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2022. Investigation of mitochondrial bioenergetic profile and dysfunction in atherosclerosis. Ramji, Dipak, ed. Atherosclerosis: Methods and Protocols, Vol. 2419. Methods in Molecular Biology, New York, NY: Springer, (10.1007/978-1-0716-1924-7_19)

Alahmadi, Alaa and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2022. Monitoring modified lipoprotein uptake and macropinocytosis associated with macrophage foam cell formation. Ramji, Dipak, ed. Atherosclerosis: Methods and Protocols, Vol. 2419. Methods in Molecular Biology, New York, NY: Springer, pp. 247-255. (10.1007/978-1-0716-1924-7_14)

Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578, Chan, Yee-Hung, Alahmadi, Alaa, Alotibi, Reem and Alshehri, Nouf 2022. Survey of approaches for investigation of atherosclerosis in vivo. Ramji, Dipak, ed. Atherosclerosis: Methods and Protocols, Vol. 2419. Methods in Molecular Biology, New York, NY: Springer, pp. 57-72. (10.1007/978-1-0716-1924-7_4)

Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578, Ismail, Alaa, Chen, Jing, Alradi, Fahad and Al Alawi, Sulaiman 2022. Survey of in vitro model systems for Investigation of key cellular processes associated with atherosclerosis. Ramji, Dipak P., ed. Atherosclerosis: Methods and Protocols, Vol. 2419. New York, NY: Springer, pp. 39-56. (10.1007/978-1-0716-1924-7_3)

Chan, Yee-Hung and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2022. Key roles of inflammation in atherosclerosis: mediators involved in orchestrating the inflammatory response and its resolution in the disease along with therapeutic avenues targeting inflammation. Ramji, Dipak, ed. Atherosclerosis: Methods and Protocols, Vol. 2419. Methods in Molecular Biology, New York, NY: Springer, pp. 21-37. (10.1007/978-1-0716-1924-7_2)

Chan, Yee-Hung and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2022. Atherosclerosis: pathogenesis and key cellular processes, current and emerging therapies, key challenges, and future research directions. Ramji, Dipak, ed. Atherosclerosis: Methods and Protocols, Vol. 2419. Methods in Molecular Biology, New York, NY: Springer, pp. 3-19. (10.1007/978-1-0716-1924-7_1)

Al-Ahmadi, Wijdan, Webberley, Thomas S., Joseph, Alex, Harris, Ffion, Chan, Yee-Hung, Alotibi, Reem, Williams, Jessica O., Alahmadi, Alaa, Decker, Thomas, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490 and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2021. Pro-atherogenic actions of signal transducer and activator of transcription 1 serine 727 phosphorylation in LDL receptor deficient mice via modulation of plaque inflammation. FASEB Journal 35 (10) , e21892. 10.1096/fj.202100571RR

O'Morain, Victoria L., Chan, Yee-Hung, Williams, Jessica O., Alotibi, Reem, Alahmadi, Alaa, Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733, Plummer, Sue F., Hughes, Timothy R., Michael, Daryn R. and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2021. The Lab4P consortium of probiotics attenuates atherosclerosis in LDL receptor deficient mice fed a high fat diet and causes plaque stabilization by inhibiting inflammation and several pro-atherogenic processes. Molecular Nutrition & Food Research 65 (17) , 2100214. 10.1002/mnfr.202100214

Moss, Joe W. E. ORCID: https://orcid.org/0000-0002-1866-9752, Williams, Jessica O., Al-Ahmadi, Wijdan, O'Morain, Victoria, Chan, Yee-Hung, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Menendez-Gonzalez, Juan B., Almotiri, Alhomidi, Plummer, Sue F., Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733, Michael, D. R. and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2021. Protective effects of a unique combination of nutritionally active ingredients on risk factors and gene expression associated with atherosclerosis in C57BL/6J mice fed a high fat diet. Food and Function 12 (8) , pp. 3657-3671. 10.1039/D0FO02867C

Chan, Yee-Hung and Ramji, Dipak ORCID: https://orcid.org/0000-0002-6419-5578 2020. A perspective on targeting inflammation and cytokine actions in atherosclerosis. Future Medicinal Chemistry 12 (7) , pp. 613-626. 10.4155/fmc-2019-0301

O'Morain, Victoria and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2020. The potential of probiotics in the prevention and treatment of atherosclerosis. Molecular Nutrition and Food Research 64 (4) , 1900797. 10.1002/mnfr.201900797

Gallagher, Hayley, Williams, Jessica O., Ferekidis, Nele, Ismail, Alaa, Chan, Yee-Hung, Michael, Daryn R., Guschina, Irina A., Tyrrell, Victoria J., O'Donnell, Valerie B. ORCID: https://orcid.org/0000-0003-4089-8460, Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612, Khozin-Goldberg, Inna, Boussiba, Sammy and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2019. Dihimo-γ-linolenic acid inhibits several key cellular processes associated with atherosclerosis. BBA - Molecular Basis of Disease 1865 (9) , pp. 2538-2550. 10.1016/j.bbadis.2019.06.011

Buckley, Melanie L., Williams, Jessica O. ORCID: https://orcid.org/0000-0003-2948-7548, Chan, Yee-Hung, Laubertova, Lucia, Gallagher, Hayley, Moss, Joe W. E. ORCID: https://orcid.org/0000-0002-1866-9752 and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2019. The interleukin-33-mediated inhibition of expression of two key genes implicated in atherosclerosis in human macrophages requires MAP kinase, phosphoinositide 3-kinase and nuclear factor-κB signaling pathways. Scientific Reports 9 , 11317. 10.1038/s41598-019-47620-8

Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2019. Polyunsaturated fatty acids and atherosclerosis: insights from pre-clinical studies. European Journal of Lipid Science and Technology 121 (1) , 1800029. 10.1002/ejlt.201800029

Moss, Joe ORCID: https://orcid.org/0000-0002-1866-9752, Williams, Jessica and Ramji, Dipak ORCID: https://orcid.org/0000-0002-6419-5578 2018. Nutraceuticals as therapeutic agents for atherosclerosis. Biochimica et Biophysica Acta - Molecular Basis of Disease 1864 (5. A.) , pp. 1562-1572. 10.1016/j.bbadis.2018.02.006

Moss, Joe ORCID: https://orcid.org/0000-0002-1866-9752 and Ramji, Dipak ORCID: https://orcid.org/0000-0002-6419-5578 2017. Cytokines in Atherosclerosis. Foti, Maria and Locati, Massimo, eds. Cytokine Effector Functions in Tissues, Academic Press, pp. 109-118.

Gallagher, Hayley, Moss, J.W.E, Williams, J, Davies, T.S., Al-Ahmadi, Wajdan, O'Morain, Victoria and Ramji, Dipak ORCID: https://orcid.org/0000-0002-6419-5578 2017. Nutraceuticals in the prevention and treatment of Atherosclerosis. Cardiology 137 (S1) , p. 264. 10.1159/000477751

Michael, D. R., Davies, T. S., Moss, J. W. E., Calvente, D. Lama, Ramji, D. P. ORCID: https://orcid.org/0000-0002-6419-5578, Marchesi, J. R. ORCID: https://orcid.org/0000-0002-7994-5239, Pechlivanis, A., Plummer, S. F. and Hughes, T. R. ORCID: https://orcid.org/0000-0003-2348-3490 2017. The anti-cholesterolaemic effect of a consortium of probiotics: An acute study in C57BL/6J mice. Scientific Reports 7 , 2883. 10.1038/s41598-017-02889-5

Salter, Rebecca C., Foka, Pelagia, Davies, Thomas S., Gallagher, Hayley, Michael, Daryn R., Ashlin, Tim G. and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2016. The role of mitogen-activated protein kinases and sterol receptor coactivator-1 in TGF-β-regulated expression of genes implicated in macrophage cholesterol uptake. Scientific Reports 6 , 34368. 10.1038/srep34368

Moss, Joe W. E. ORCID: https://orcid.org/0000-0002-1866-9752 and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2016. Nutraceutical therapies for atherosclerosis. Nature Reviews Cardiology 13 (9) , pp. 513-532. 10.1038/nrcardio.2016.103

Moss, Joe ORCID: https://orcid.org/0000-0002-1866-9752 and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2016. Cytokines: roles in atherosclerosis disease progression and potential therapeutic targets. Future Medicinal Chemistry 8 (11) , pp. 1317-1330. 10.4155/fmc-2016-0072

Davies, T.S., Gallagher, Hayley, Moss, J. W. E., Jaffar, F.B., Al-Ahmadi, Wajdan, Harris, Ffion and Ramji, Dipak ORCID: https://orcid.org/0000-0002-6419-5578 2016. The action of Nutraceuticals on key macrophage processes associated with Atherosclerosis. Cardiology 134 (S1) , p. 314. 10.1159/000447505

Ramji, Dipak ORCID: https://orcid.org/0000-0002-6419-5578, Davies, Thomas, Gallagher, Hayley, Moss, Joe ORCID: https://orcid.org/0000-0002-1866-9752, Faizah, Jaffar and Al-Ahmadi, Wajdan 2016. Cytkines in atherosclerosis: molecular mechanisms underlying their actions and promising therapeutic targets [Abstract]. Journal of Clinical and Experimental Cardiology 7 (6) , p. 52.

Ramji, Dipak ORCID: https://orcid.org/0000-0002-6419-5578, Davies, Thomas, Gallagher, Hayley, Moss, Joe ORCID: https://orcid.org/0000-0002-1866-9752, Faizah, Jaffar and Al-Ahmadi, Wajdan 2016. Nutraceuticals as preventative and therapeutic agents in atherosclerosis. Journal of Clinical and Experimental Cardiology 7 (6) , p. 31. 10.4172/2155-9880.C1.029

Michael, D. R., Moss, Joe W. E. ORCID: https://orcid.org/0000-0002-1866-9752, Calvente, D. Lama, Garaiova, I., Plummer, S. F. and Ramji, Dipak ORCID: https://orcid.org/0000-0002-6419-5578 2016. Lactobacillus plantarum CUL66 can impact cholesterol homeostasis in Caco-2 enterocytes. Beneficial Microbes 7 (3) , pp. 443-451. 10.3920/BM2015.0146

Moss, Joe W. E. ORCID: https://orcid.org/0000-0002-1866-9752, Davies, Thomas S., Garaiova, Iveta, Plummer, Sue F., Michael, Daryn R. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2016. A unique combination of nutritionally active ingredients can prevent several key processes associated with atherosclerosis in vitro. PLoS ONE 11 (3) , e0151057. 10.1371/journal.pone.0151057

Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 and Davies, Thomas S. 2015. Cytokines in atherosclerosis: key players in all stages of disease and promising therapeutic targets. Cytokine & Growth Factor Reviews 26 (6) , pp. 673-685. 10.1016/j.cytogfr.2015.04.003

Huwait, Etimad A., Singh, Nishi N., Michael, Daryn R., Davies, Thomas, Moss, Joe W. E. ORCID: https://orcid.org/0000-0002-1866-9752 and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2015. Protein Kinase C is involved in the induction of ATP-Binding cassette transporter A1 expression by liver X receptor/retinoid X receptor agonist in human macrophages. Journal of Cellular Biochemistry 116 (9) , pp. 2032-2038. 10.1002/jcb.25157

Moss, Joe ORCID: https://orcid.org/0000-0002-1866-9752 and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2015. Interferon-γ: Promising therapeutic target in atherosclerosis. World Journal of Experimental Medicine 5 (3) , pp. 154-159. 10.5493/wjem.v5.i3.154

Buckley, Melanie and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2015. The influence of dysfunctional signaling and lipid homeostasis in mediating the inflammatory responses during atherosclerosis. Biochimica et Biophysica Acta - Molecular Basis of Disease 1852 (7) , pp. 1498-1510. 10.1016/j.bbadis.2015.04.011

Michael, Daryn R., Davies, Thomas, Laubertová, Lucia, Gallagher, Hayley and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2015. The phosphoinositide 3-kinase signaling pathway is involved in the control of modified low-density lipoprotein uptake by human macrophages. Lipids 50 (3) , pp. 253-260. 10.1007/s11745-015-3993-0

Davies, T. S., Gallagher, H., Jaafar, F., Moss, J. W., Hughes, Timothy Rutland ORCID: https://orcid.org/0000-0003-2348-3490 and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2015. Interferon gamma signalling in atherosclerosis: pro-atherogenic actions and therapeutic approaches. Cardiology 131 , p. 292.

Willis, G. R., Connolly, K. ORCID: https://orcid.org/0000-0003-1074-1710, Ladell, K. ORCID: https://orcid.org/0000-0002-9856-2938, Davies, T. S., Guschina, I. A., Ramji, D. ORCID: https://orcid.org/0000-0002-6419-5578, Miners, K., Price, D. A. ORCID: https://orcid.org/0000-0001-9416-2737, Clayton, A. ORCID: https://orcid.org/0000-0002-3087-9226, James, P. E. and Rees, D. A. ORCID: https://orcid.org/0000-0002-1165-9092 2014. Young women with polycystic ovary syndrome have raised levels of circulating annexin V-positive platelet microparticles. Human Reproduction 29 (12) , pp. 2756-2763. 10.1093/humrep/deu281

Davies, T. S., Li, N., McLaren, James ORCID: https://orcid.org/0000-0002-7021-5934, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490 and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2014. Pro- therogenic actions of interferon-gamma on macrophages in atherosclerosis. Cardiology 128 (S1) , p. 278. 10.1159/000365062

Ashlin, Timothy Gordon, Buckley, Melanie, Salter, Rebecca C., Johnson, Jason L., Kwan, Alvin P. L. and Ramji, Dipak ORCID: https://orcid.org/0000-0002-6419-5578 2014. The anti-atherogenic cytokine interleukin-33 inhibits the expression of a disintegrin and metalloproteinase with thrombospondin motifs-1,-4 and-5 in human macrophages: Requirement of extracellular signal-regulated kinase, c-Jun N-terminal kinase and phosphoinositide 3-kinase signaling pathways. The International Journal of Biochemistry & Cell Biology 46 , pp. 113-123. 10.1016/j.biocel.2013.11.008

Michael, Daryn Robert, Ashlin, Timothy Gordon, Davies, Charlotte S., Gallagher, Hayley, Stoneman, Thomas W., Buckley, Melanie and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2013. Differential regulation of macropinocytosis in macrophages by cytokines: Implications for foam cell formation and atherosclerosis. Cytokine 64 (1) , pp. 357-361. 10.1016/j.cyto.2013.05.016

Ashlin, Timothy Gordon, Kwan, Alvin P. L. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2013. Regulation of ADAMTS-1, -4 and -5 expression in human macrophages: differential regulation by key cytokines implicated in atherosclerosis and novel synergism between TL1A and IL-17. Cytokine 64 (1) , pp. 234-242. 10.1016/j.cyto.2013.06.315

Michael, Daryn Robert, Salter, Rebecca C. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2012. TGF-β inhibits the uptake of modified low density lipoprotein by human macrophages through a Smad-dependent pathway: A dominant role for Smad-2. Biochimica et Biophysica Acta - Molecular Basis of Disease 1822 (10) , pp. 1608-1616. 10.1016/j.bbadis.2012.06.002

Michael, Daryn Robert, Ashlin, Timothy Gordon, Buckley, Melanie and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2012. Liver X receptors, atherosclerosis and inflammation. Current Atherosclerosis Reports 14 (3) , pp. 284-293. 10.1007/s11883-012-0239-y

Michael, Daryn Robert, Ashlin, Timothy Gordon, Buckley, Melanie and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2012. Macrophages, lipid metabolism and gene expression in atherogenesis: a therapeutic target of the future? Clinical Lipidology 7 (1) , pp. 37-48. 10.2217/clp.11.73

McLaren, James Edward ORCID: https://orcid.org/0000-0002-7021-5934, Michael, Daryn Robert, Guschina, Irina, Harwood, John L. ORCID: https://orcid.org/0000-0003-2377-2612 and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2011. Eicosapentaenoic acid and docosahexaenoic acid regulate modified LDL uptake and macropinocytosis in human macrophages. Lipids 46 (11) , pp. 1053-1061.

McLaren, James Edward ORCID: https://orcid.org/0000-0002-7021-5934, Michael, Daryn Robert, Ashlin, Timothy Gordon and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2011. Cytokines, macrophage lipid metabolism and foam cells: implications for cardiovascular disease therapy. Progress in Lipid Research 50 (4) , pp. 331-347. 10.1016/j.plipres.2011.04.002

Salter, Rebecca, Arnaoutakis, Konstantinos, Michael, Daryn Robert, Singh, Nishi, Ashlin, Timothy Gordon, Buckley, Melanie, Kwan, Alvin and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2011. The expression of a disintegrin and metalloproteinase with thrombospondin motifs 4 in human macrophages is inhibited by the anti-atherogenic cytokine transforming growth factor-β and requires Smads, p38 mitogen-activated protein kinase and c-Jun. The International Journal of Biochemistry & Cell Biology 43 (5) , pp. 805-811. 10.1016/j.biocel.2011.02.005

Huwait, Etimad, Greenow, Kirsty Rhian, Singh, Nishi and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2011. A novel role for c-Jun N-terminal kinase and phosphoinositide 3-kinase in the liver X receptor-mediated induction of macrophage gene expression. Cellular Signalling 23 (3) , pp. 542-549. 10.1016/j.cellsig.2010.11.002

Li, Na, Salter, Rebecca Claire and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2011. Molecular mechanisms underlying the inhibition of IFN-γ-induced, STAT1-mediated gene transcription in human macrophages by simvastatin and agonists of PPARs and LXRs. Journal of Cellular Biochemistry 112 (2) , pp. 675-683. 10.1002/jcb.22976

McLaren, J. E., Calder, C. J., McSharry, B. P., Sexton, K., Salter, R. C., Singh, N. N., Wilkinson, G. W. G., Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 and Wang, E. C. Y. 2010. In vitro promotion of macrophage foam cell formation by Death Receptor 3 and its ligand TL1A. Immunology 131 (1) , p. 103.

Li, Na, McLaren, James Edward ORCID: https://orcid.org/0000-0002-7021-5934, Michael, Daryn Robert, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153 and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2010. ERK is integral to the IFN-γ-mediated activation of STAT1, the expression of key genes implicated in atherosclerosis, and the uptake of modified lipoproteins by human macrophages. The Journal of Immunology 185 (5) , pp. 3041-3048. 10.4049/jimmunol.1000993

McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934, Michael, Daryn Robert, Salter, Rebecca Claire, Ashlin, Timothy Gordon, Calder, Claudia Jane, Miller, Ashley M., Liew, Foo Y. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2010. IL-33 reduces macrophage foam cell formation. The Journal of Immunology 185 (2) , pp. 1222-1229. 10.4049/jimmunol.1000520

McLaren, James Edward ORCID: https://orcid.org/0000-0002-7021-5934, Calder, Claudia Jane, McSharry, Brian P., Sexton, Keith John, Salter, Rebecca Claire, Singh, Nishi N., Wilkinson, Gavin William Grahame ORCID: https://orcid.org/0000-0002-5623-0126, Wang, Edward Chung Yern ORCID: https://orcid.org/0000-0002-2243-4964 and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2010. The TNF-like protein 1A-death receptor 3 pathway promotes macrophage foam cell formation in vitro. Journal of Immunology 184 (10) , pp. 5827-5834. 10.4049/jimmunol.0903782

Salter, Rebecca C., Ashlin, Timothy G., Kwan, Alvin P. L. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2010. ADAMTS proteases: key roles in atherosclerosis? Journal of Molecular Medicine 88 (12) , pp. 1203-1211. 10.1007/s00109-010-0654-x

Ali, S., Singh, N. N., Yildirim, H. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2010. Requirement for nuclear factor kappa B signalling in the interleukin-1-induced expression of the CCAAT/enhancer binding protein-delta gene in hepatocytes. International Journal of Biochemistry & Cell Biology 42 (1) , pp. 113-119. 10.1016/j.biocel.2009.09.018

McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934 and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578 2009. Interferon gamma: A master regulator of atherosclerosis. Cytokine & Growth Factor Reviews 20 (2) , pp. 125-135. 10.1016/j.cytogfr.2008.11.003

Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2009. Growth hormone-releasing peptides, CD36, and stimulation of cholesterol efflux: cyclooxygenase-2 is the link. Cardiovascular Research 83 (3) , pp. 419-420. 10.1093/cvr/cvp195

Foka, P., Singh, N. N., Salter, Rebecca Claire and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2009. The tumour necrosis factor-a-mediated suppression of the CCAAT/enhancer binding protein-a gene transcription in hepatocytes involves inhibition of autoregulation. International Journal of Biochemistry & Cell Biology 41 (5) , pp. 1189-1197. 10.1016/j.biocel.2008.10.024

Singh, Nishi Nihar, Salter, Rebecca Claire and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2008. Molecular mechanisms underlying transforming growth factor-beta-induced expression of the apolipoprotein E gene [Abstract]. Atherosclerosis Supplements 9 (1) , p. 21. 10.1016/S1567-5688(08)70078-3

Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578, Singh, Nishi Nihar, Li, Na, Salter, Rebecca Claire, Harvey, Elizabeth Jane and Foka, Pelagia 2008. Cytokine signalling in macrophages and the expression of key genes implicated in atherosclerosis [Abstract]. Atherosclerosis Supplements 9 (1) , p. 53. 10.1016/S1567-5688(08)70209-5

Harris, S. M., Harvey, E. J., Hughes, T. R. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2008. The interferon-γ-mediated inhibition of lipoprotein lipase gene transcription in macrophages involves casein kinase 2- and phosphoinositide-3-kinase-mediated regulation of transcription factors Sp1 and Sp3. Cellular Signalling 20 (12) , pp. 2296-2301. 10.1016/j.cellsig.2008.08.016

Singh, N. N. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2008. Protein kinase CK2, an important regulator of the inflammatory response? Journal of Molecular Medicine 86 (8) , pp. 887-897. 10.1007/s00109-008-0352-0

Singh, N. N., Foka, P., Harvey, E. J., Huwait, E., Ali, S., Li, N., Salter, R. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2007. Signaling pathways underlying cytokine regulated expression of key genes in macrophages implicated in atherosclerosis. Atherosclerosis Supplements 8 (1) , p. 4.

Harvey, E. J., Li, N. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2007. Critical role for casein kinase 2 and phosphoinositide-3-kinase in the interferon- -induced expression of monocyte chemoattractant protein-1 and other key genes implicated in atherosclerosis. Arteriosclerosis Thrombosis and Vascular Biology 27 (4) , pp. 806-812. 10.1161/01.ATV.0000258867.79411.96

Monslow, Jamie, Williams, John David, Fraser, Donald James ORCID: https://orcid.org/0000-0003-0102-9342, Michael, Daryn Robert, Foka, Pelagia, Kift-Morgan, Ann Patricia, Luo, Dong Dong, Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Craig, Kathrine Jane, Topley, Nicholas, Jones, Simon Arnett ORCID: https://orcid.org/0000-0001-7297-9711, Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 and Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435 2006. Sp1 and Sp3 mediate constitutive transcription of the human hyaluronan synthase 2 gene. The Journal of Biological Chemistry 281 (26) , pp. 18043-18050. 10.1074/jbc.M510467200

Foka, P., Singh, N. N., Irvine, S. A., Harvey, E. J., Huwait, E., Rogers, S. A., Ali, S., Arnaoutakis, K., Li, N. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2006. Signalling pathways underlying transforming growth factor-beta regulated expression of key genes implicated in the control of foam cell formation. Atherosclerosis Supplements 7 (3) , p. 237.

Kockar, F., Yildirim, H. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2006. Molecular characterisation and comparative analysis of the human C/EBP delta promoter to mammalian homologues. FEBS Letters 273 , p. 334.

Singh, N. N., Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578, Foka, P., Irvine, S. A. and Arnaoutakis, K. 2006. Transforming growth factor-b-regulated expression of genes in macrophages implicated in the control of cholesterol homoeostasis. Biochemical Society Transactions 34 (6) , p. 1141. 10.1042/BST0341141

Singh, Nishi N. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2006. The role of transforming growth factor-β in atherosclerosis. Cytokine & Growth Factor Reviews 17 (6) , pp. 487-499. 10.1016/j.cytogfr.2006.09.002

Singh, Nishi N. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2006. Transforming growth factor-β-induced expression of the apolipoprotein e gene requires c-Jun N-terminal kinase, p38 kinase, and casein kinase 2. Arteriosclerosis Thrombosis and Vascular Biology 26 (6) , pp. 1323-1329. 10.1161/01.ATV.0000220383.19192.55

Irvine, Scott A., Martin, John, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490 and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2006. Lipoprotein lipase is expressed by glomerular mesangial cells. The International Journal of Biochemistry & Cell Biology 38 (1) , pp. 12-16. 10.1016/j.biocel.2005.07.008

Harvey, E. J. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2005. Up-regulation of monocyte chemoattractant protein-1 and the monocyte chemoattractant protein-1 receptor (CCR2) in macrophages by the pro-inflammatory cytokine interferon-gamma. Arteriosclerosis Thrombosis and Vascular Biology 25 (5) , E64-E64.

Foka, P., Singh, N. N., Irvine, S. A., Greenow, K., Evans, S., Rogers, S., Harvey, E., Ali, S., Arnaoutakis, K.. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2005. Molecular mechanisms involved in the cytokine-regulated expression of genes in macrophages implicated in foam cell formation and atherosclerosis. Arteriosclerosis Thrombosis and Vascular Biology 25 (5) , E71-E71.

Irvine, Scott A., Foka, Pelagia, Rogers, Sarah Ann, Mead, James R. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2005. A critical role for the Sp1-binding sites in the transforming growth factor-β-mediated inhibition of lipoprotein lipase gene expression in macrophages. Nucleic Acids Research , pp. 1423-1434. 10.1093/nar/gki280

Harvey, E. J. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2005. Interferon-γ and atherosclerosis: pro- or anti-atherogenic? Cardiovascular Research 67 (1) , pp. 11-20. 10.1016/j.cardiores.2005.04.019

Greenow, Kirsty, Pearce, Nigel J. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2005. The key role of apolipoprotein E in atherosclerosis. Journal of Molecular Medicine 83 (5) , pp. 329-342. 10.1007/s00109-004-0631-3

Greenow, Kirsty Rhian, Pearce, N. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2004. A critical role for the phosphoinositide-3-kinase signal transduction pathway in the activation of apolipoprotein E gene expression. Atherosclerosis Supplements 5 (1) , p. 25. 10.1016/S1567-5688(04)90110-4

Foka, P., Irvine, S. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2004. Regulation of CCAAT/enhancer binding protein-alpha gene transcription by interleukin-6. Atherosclerosis Supplements 5 (1) , p. 31.

Irvine, S. A., Foka, P. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2004. Transcriptional regulation of macrophage lipoprotein lipase gene expression by transforming growth factor-beta. Atherosclerosis Supplements 5 (1) , pp. 31-32. 10.1016/S1567-5688(04)90137-2

Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578, Foka, P., Irvine, S., Hughes, T., Rogers, S., Singh, N., Greenow, K., Evans, S., Harvey, E. and Ali, S. 2004. Signal transduction pathways and transcriptional control mechanisms involved in the cytokine-mediated, regulation of key genes in macrophages implicated in foam cell formation and atherosclerosis. Atherosclerosis Supplements 5 (1) , pp. 29-30.

Foka, Pelagia, Irvine, Scott A., Kockar, Feray Tura and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2003. Interleukin-6 represses the transcription of the CCAAT/enhancer binding protein-α in hepatoma cells by inhibiting its ability to autoactivate the proximal promoter region. Nucleic Acids Research , pp. 6722-6732. 10.1093/nar/gkg861

Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578, Hughes, T. R., Irvine, S. A., Mead, J. R., Foka, P., Evans, S. and Harvey, E. 2003. Novel pathways for cytokine-mediated regulation of macrophage lipoprotein lipase gene expression. Atherosclerosis Supplements 4 (2) , p. 62. 10.1016/S1567-5688(03)90263-7

Mead, James R., Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Irvine, Scott A., Singh, Nishi Nihar and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2003. Interferon-γ stimulates the expression of the inducible cAMP early repressor in macrophages through the activation of casein kinase 2: A Potentially novel pathway for interferon-γ-mediated inhibition of gene transcription. Journal of Biological Chemistry , pp. 17741-17751. 10.1074/jbc.M301602200

Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 and Foka, Pelagia 2002. CCAAT/Enhancer binding proteins: structure, function and regulation. Biochemical Journal 365 , pp. 561-575. 10.1042/BJ20020508

Mead, J. R. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2002. The pivotal role of lipoprotein lipase in atherosclerosis. Cardiovascular Research 55 (2) , pp. 261-269. 10.1016/S0008-6363(02)00405-4

Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Tengku-Muhammad, T. S., Irvine, S. A. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2002. A novel role of Sp1 and Sp3 in the interferon- -mediated suppression of macrophage lipoprotein lipase gene transcription. Journal of Biological Chemistry 277 (13) , pp. 11097-11106. 10.1074/jbc.M106774200

Mead, James, Irvine, Scott and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2002. Lipoprotein lipase: structure, function, regulation, and role in disease. Journal of Molecular Medicine 80 (12) , pp. 753-769. 10.1007/s00109-002-0384-9

Kockar, Feray Tura, Foka, Pelagia, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490, Kousteni, Stavroula and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2001. Analysis of the Xenopus laevis CCAAT-enhancer binding protein α gene promoter demonstrates species-specific differences in the mechanisms for both auto-activation and regulation by Sp1. Nucleic Acids Research 29 (2) , pp. 362-372. 10.1093/nar/29.2.362

Foka, Pelagia, Kousteni, Stavroula and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2001. Molecular characterization of the xenopus CCAAT-enhancer binding protein β gene promoter. Biochemical and Biophysical Research Communications 285 (2) , pp. 430-436. 10.1006/bbrc.2001.5203

Tengku-Muhammad, Tengu S., Hughes, Timothy R., Ranki, Harri, Cryer, Anthony and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2000. Differential regulation of macrophage ccaat- enhancer binding protein isoforms by lipopolysaccharide and cytokines. Cytokine 12 (9) , pp. 1430-1436. 10.1006/cyto.2000.0711

Granger, Rachel L., Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490 and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2000. Gene, stimulus and cell-type specific regulation of activator protein-1 in mesangial cells by lipopolysaccharide and cytokines. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1492 (1) , pp. 100-107. 10.1016/S0167-4781(00)00089-0

Granger, Rachel L, Hughes, Timothy Richard ORCID: https://orcid.org/0000-0003-2348-3490 and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2000. Stimulus- and cell-type-specific regulation of CCAAT-enhancer binding protein isoforms in glomerular mesangial cells by lipopolysaccharide and cytokines. Biochimica et Biophysica Acta - Molecular Basis of Disease 1501 (2-3) , pp. 171-179. 10.1016/S0925-4439(00)00016-8

Tengku-Muhammad, Tengku S., Hughes, Timothy R, Foka, Pelagia, Cryer, Anthony and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2000. Cytokine-mediated differential regulation of macrophage activator protein-1 genes. Cytokine 12 (6) , pp. 720-726. 10.1006/cyto.1999.0620

Davies, Gareth E., Sabatakos, Georgios, Cryer, Anthony and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 2000. The ovine CCAAT-enhancer binding protein δ gene: cloning, characterization, and species-specific autoregulation. Biochemical and Biophysical Research Communications 271 (2) , pp. 346-352. 10.1006/bbrc.2000.2630

Mead, James R., Cryer, Anthony and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 1999. Lipoprotein lipase, a key role in atherosclerosis? FEBS Letters 462 (1-2) , pp. 1-6. 10.1016/S0014-5793(99)01495-7

Kousteni, S., Tura-Kockar, F. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 1999. Sequence and expression analysis of a novel Xenopus laevis cDNA that encodes a protein similar to bacterial and chloroplast ribosomal protein L24. Gene 235 (1-2) , pp. 13-18. 10.1016/S0378-1119(99)00221-8

Tengku-Muhammad, T. S., Hughes, T., Cryer, A. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 1999. Involvement of both the tyrosine kinase and the phosphatidylinositol-3 ' kinase signal transduction pathways in the regulation of lipoprotein lipase expression in J774.2 macrophages by cytokines and lipopolysaccharide. Cytokine 11 (7) , pp. 463-468. 10.1006/cyto.1998.0460

Tengku-Muhammad, T. S., Hughes, T. R., Cryer, A and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 1999. Synergism between lipopolysaccharide and interferon gamma in the regulation of lipoprotein lipase in macrophages. Cytokine 11 (6) , pp. 408-415. 10.1006/cyto.1998.0447

Sabatakos, G., Kousteni, S., Cryer, A. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 1998. Rapid communication: Nucleotide sequence of ovine C/EBP epsilon gene. Journal of Animal Science 76 (11) , pp. 2953-2954.

Kousteni, Stavroula, Kockar, Feray Tura, Sweeney, Glen E. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 1998. Characterisation and developmental regulation of the Xenopus laevis CCAAT-enhancer binding protein β gene. Mechanisms of Development 77 (2) , pp. 143-148. 10.1016/S0925-4773(98)00128-2

Kousteni, Stavroula, Tura, Feray, Sweeney, Glen E. and Ramji, Dipak Purshottam ORCID: https://orcid.org/0000-0002-6419-5578 1997. Sequence and expression analysis of a Xenopus laevis cDNA which encodes a homologue of mammalian 14-3-3 zeta protein. Gene 190 (2) , pp. 279-285. 10.1016/S0378-1119(97)00013-9