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Number of items: 26.

Zelek, Wioleta M. and Morgan, B. Paul 2022. Targeting complement in neurodegeneration: challenges, risks, and strategies. Trends in Pharmacological Sciences 43 (8) , pp. 615-628. 10.1016/j.tips.2022.02.006

Carpanini, Sarah M., Torvell, Megan, Bevan, Ryan J., Byrne, Robert A. J., Daskoulidou, Nikoleta, Saido, Takaomi C., Taylor, Philip R., Hughes, Timothy R., Zelek, Wioleta M. and Morgan, B. Paul 2022. Terminal complement pathway activation drives synaptic Loss in Alzheimer’s disease models. Acta Neuropathologica Communications 10 , 99. 10.1186/s40478-022-01404-w

Fielding, Ceri Alan, Sabberwal, Pragati, Williamson, James C., Greenwood, Edward J.D., Crozier, Thomas WM, Zelek, Wioleta, Seow, Jeffrey, Graham, Carl, Huettner, Isabella, Edgeworth, Jonathan D., Price, David A., Morgan, Paul B., Ladell, Kristin, Eberl, Matthias, Humphreys, Ian R., Merrick, Blair, Doores, Katie, Wilson, Sam J., Lehner, Paul J., Wang, Eddie C.Y. and Stanton, Richard J. 2022. SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies. eLife 11 10.7554/eLife.74489

Lewis, Lisa A, Gulati, Sunita, Zelek, Wioleta M., Morgan, B. Paul, Song, Wen-Chao, Zheng, Bo, Nowak, Nancy, DeOliveira, Rosane B., Sanchez, Bryan, DeSouza Silva, Leandro, Schuurman, Janine, Beurskens, Frank, Ram, Sanjay and Rice, Peter A 2022. Efficacy of an experimental gonococcal lipooligosaccharide mimitope vaccine requires terminal complement. The Journal of Infectious Diseases 225 (10) , 1861–1864. 10.1093/infdis/jiab630
Item availability restricted.

Kolka, Cathryn M., Webster, Julie, Lepletier, Ailin, Winterford, Clay, Brown, Ian, Richards, Renee S., Zelek, Wioleta M., Cao, Yilang, Khamis, Ramlah, Shanmugasundaram, Karthik B., Wuethrich, Alain, Trau, Matt, Brosda, Sandra, Barbour, Andrew, Shah, Alok K., Eslick, Guy D., Clemons, Nicholas J., Morgan, B. Paul and Hill, Michelle M. 2022. C5b-9 membrane attack complex formation and extracellular vesicle shedding in Barrett's esophagus and esophageal adenocarcinoma. Frontiers in Immunology 13 , 842023. 10.3389/fimmu.2022.842023

Scurr, Martin, Zelek, Wioleta, Lippiatt, George, Somerville, Michelle, Burnell, Stephanie, Capitani, Lorenzo, Davies, Kate, Lawton, Helen, Tozer, Thomas, Rees, Tara, Roberts, Kerry, Evans, Mererid, Jackson, Amanda, Young, Charlotte, Fairclough, Lucy, Tighe, Paddy, Wills, Mark, Westwell, Andrew, Morgan, Bryan Paul, Gallimore, Awen and Godkin, Andrew 2022. Whole blood-based measurement of SARS-CoV-2-specific T cells reveals asymptomatic infection and vaccine immunogenicity in healthy subjects and patients with solid organ cancers. Immunology 165 (2) , pp. 250-259. 10.1111/imm.13433

Syrimi, Eleni, Fennell, Eanna, Richter, Alex, Vrljicak, Pavle, Stark, Richard, Ott, Sascha, Murray, Paul G., Al-Abadi, Eslam, Chikermane, Ashish, Dawson, Pamela, Hackett, Scott, Jyothish, Deepthi, Kanthimathinathan, Hari Krishnan, Monaghan, Sean, Nagakumar, Prasad, Scholefield, Barnaby R., Welch, Steven, Khan, Naeem, Faustini, Sian, Davies, Kate, Zelek, Wioleta M., Kearns, Pamela and Taylor, Graham S. 2021. The immune landscape of SARS-CoV-2-associated multisystem inflammatory syndrome in children (MIS-C) from acute disease to recovery. iScience 24 (11) , 103215. 10.1016/j.isci.2021.103215

Zelek, Wioleta 2021. Measuring total classical pathway and activities of individual components of the mouse complement pathway. Bio-protocol 11 (19) , e4175. 10.21769/BioProtoc.4175

Mc Mahon, O., Hallam, T. M., Patel, S., Harris, C. L., Menny, A., Zelek, W. M., Widjajahakim, R., Java, A., Cox, T., Tzoumas, N., Steel, D. H. W., Shuttleworth, V. G., Smith-Jackson, K., Brocklebank, V., Griffiths, H., Cree, A. J., Atkinson, J. P., Lotery, A. J., Bubeck, D., Morgan, B. P., Marchbank, K. J., Seddon, J. M. and Kavanagh, D. 2021. The rare C9 P167S risk variant for age-related macular degeneration increases polymerization of the terminal component of the complement cascade. Human Molecular Genetics 30 (13) , pp. 1188-1199. 10.1093/hmg/ddab086

Webster, Julie A., Wuethrich, Alain, Shanmugasundaram, Karthik B., Richards, Renee S., Zelek, Wioleta M., Shah, Alok K., Gordon, Louisa G., Kendall, Bradley J., Hartel, Gunter, Morgan, B. Paul, Trau, Matt and Hill, Michelle M. 2021. Development of EndoScreen chip, a microfluidic pre-endoscopy triage test for esophageal adenocarcinoma. Cancers 13 (12) , 2865. 10.3390/cancers13122865

Moat, Stuart James, Zelek, Wiola M., Carne, Emily, Ponsford, Mark J., Bramhall, Kathyryn, Jones, Sara, El-Shanawany, Tariq, Wise, Matthew J., Thomas, Annette, George, Chloe, Fegan, Christopher, Steven, Rachael, Webb, Russell, Weeks, Ian, Morgan, Brian Paul and Jolles, Stephen 2021. Development of a high throughput SARS-CoV-2 antibody testing pathway using dried blood spot specimens. Annals of Clinical Biochemistry 58 (2) 10.1177/0004563220981106

Murrell, Isa, Forde, Donall, Zelek, Wioleta, Tyson, Linda, Chichester, Lisa, Palmer, Nicki, Jones, Rachel, Morgan, B. Paul and Moore, Catherine 2021. Temporal development and neutralising potential of antibodies against SARS-CoV-2 in hospitalised COVID-19 patients: An observational cohort study. PLoS ONE 16 (1) , e0245382. 10.1371/journal.pone.0245382

Buckland, Matthew S., Galloway, James B., Fhogartaigh, Caoimhe Nic, Meredith, Luke, Provine, Nicholas M., Bloor, Stuart, Ogbe, Ane, Zelek, Wioleta M., Smielewska, Anna, Yakovleva, Anna, Mann, Tiffeney, Bergamaschi, Laura, Turner, Lorinda, Mescia, Frederica, Toonen, Erik J. M., Hackstein, Carl-Philipp, Akther, Hossain Delowar, Vieira, Vinicius Adriano, Ceron-Gutierrez, Lourdes, Periselneris, Jimstan, Kiani-Alikhan, Sorena, Grigoriadou, Sofia, Vaghela, Devan, Lear, Sara E., Török, M. Estée, Hamilton, William L., Stockton, Joanne, Quick, Josh, Nelson, Peter, Hunter, Michael, Coulter, Tanya I., Devlin, Lisa, Bradley, John R., Smith, Kenneth G. C., Ouwehand, Willem H., Estcourt, Lise, Harvala, Heli, Roberts, David J., Wilkinson, Ian B., Screaton, Nick, Loman, Nicholas, Doffinger, Rainer, Lyons, Paul A., Morgan, B. Paul, Goodfellow, Ian G., Klenerman, Paul, Lehner, Paul J., Matheson, Nicholas J. and Thaventhiran, James E. D. 2020. Treatment of COVID-19 with remdesivir in the absence of humoral immunity: a case report. Nature Communications 11 (1) , 6385. 10.1038/s41467-020-19761-2

Zelek, Wioleta M. and Morgan, B. Paul 2020. Monoclonal antibodies capable of inhibiting complement downstream of C5 in multiple species. Frontiers in Immunology 11 (11) , 612402. 10.3389/fimmu.2020.612402

Zelek, Wioleta Milena, Fathalla, Dina, Morgan, Angharad, Touchard, Samuel, Loveless, Samantha, Tallantyre, Emma, Robertson, Neil P. and Morgan, B. Paul 2020. Cerebrospinal fluid complement system biomarkers in demyelinating disease. Multiple Sclerosis 26 (14) , pp. 1929-1937. 10.1177/1352458519887905

Zelek, Wioleta M., Cole, Jade, Ponsford, Mark J., Harrison, Richard A., Schroeder, Ben E., Webb, Nicholas, Jolles, Stephen, Fegan, Christopher, Morgan, Matt, Wise, Matt P. and Morgan, B. Paul 2020. Complement inhibition with the C5 blocker LFG316 in severe COVID-19. American Journal of Respiratory and Critical Care Medicine 202 (9) , pp. 1304-1308. 10.1164/rccm.202007-2778LE

Zelek, Wioleta M., Menzies, Georgina E., Brancale, Andrea, Stockinger, Brigitta and Morgan, B. Paul 2020. Characterising the original anti-C5 function-blocking antibody, BB5.1, for species specificity, mode of action and interactions with C5. Immunology 161 (2) , pp. 103-113. 10.1111/imm.13228

Zelek, Wioleta 2019. Targeting the terminal pathway in complement – driven disease. PhD Thesis, Cardiff University.
Item availability restricted.

Zelek, Wioleta M., Xie, Long, Morgan, B. Paul and Harris, Claire L. 2019. Compendium of current complement therapeutics. Molecular Immunology 114 , pp. 341-352. 10.1016/j.molimm.2019.07.030

Zelek, Wioleta M., Taylor, Philip R. and Morgan, B. Paul 2019. Development and characterisation of novel anti-C5 monoclonal antibodies capable of inhibiting complement in multiple species. Immunology 157 (4) , pp. 283-295. 10.1111/imm.13083

Zelek, Wioleta M., Watkins, Lewis M., Howell, Owain W., Evans, Rhian, Loveless, Sam, Robertson, Neil P., Beenes, Marijke, Willems, Loek, Brandwijk, Ricardo and Morgan, B. Paul 2019. Measurement of soluble CD59 in CSF in demyelinating disease: Evidence for an intrathecal source of soluble CD59. Multiple Sclerosis 25 (4) , pp. 523-531. 10.1177/1352458518758927

Kopczynska, Maja, Zelek, Wioleta, Touchard, Samuel, Gaughran, Fiona, Di Forti, Marta, Mondelli, Valeria, Murray, Robin, O'Donovan, Michael and Morgan, B. Paul 2019. Complement system biomarkers in first episode psychosis. Schizophrenia Research 204 , pp. 16-22. 10.1016/j.schres.2017.12.012

Zelek, Wioleta M., Harris, Claire L. and Morgan, Bryan Paul 2018. Extracting the barbs from complement assays: Identification and optimisation of a safe substitute for traditional buffers. Immunobiology 223 (12) , pp. 744-749. 10.1016/j.imbio.2018.07.016

Zelek, Wioleta M., Stott, Matthew, Walters, David, Harris, Claire L. and Morgan, B. Paul 2018. Characterising a pH-switch anti-C5 antibody as a tool for human and mouse complement C5 purification and cross-species inhibition of classical and reactive lysis. Immunology 155 (3) , pp. 396-403. 10.1111/imm.12982

Kopczynska, Maja, Zelek, Wioleta, Vespa, Simone, Touchard, Samuel, Wardle, Mark, Loveless, Samantha, Thomas, Rhys H., Hamandi, Khalid and Morgan, B. Paul 2018. Complement system biomarkers in epilepsy. Seizure - European Journal of Epilepsy 60 , pp. 1-7. 10.1016/j.seizure.2018.05.016

Boshra, Hani, Zelek, Wioleta M., Hughes, Timothy R., Rodriguez de Cordoba, Santiago and Morgan, B. Paul 2018. Absence of CD59 in guinea pigs: Analysis of the Cavia porcellus genome suggests the evolution of a CD59 pseudogene. Journal of Immunology 200 (1) , pp. 327-335. 10.4049/jimmunol.1701238

This list was generated on Fri Aug 19 06:22:40 2022 BST.