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Synthetic hookworm-derived peptides are potent modulators of primary human immune cell function that protect against experimental colitis in vivo.
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| Lutzky, Viviana P., Ratnatunga, Champa N., Smith, Daniel J., Kupz, Andreas, Doolan, Denise L., Reid, David W., Thomson, Rachel M., Bell, Scott C. and Miles, John J. 2018. Anomalies in T cell function are associated with individuals at risk of mycobacterium abscessus complex infection. Frontiers in Immunology 9 , 1319. 10.3389/fimmu.2018.01319 |
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Tungatt, Katie, Dolton, Garry, Morgan, Sophie B., Attaf, Meriem, Fuller, Anna, Whalley, Thomas, Hemmink, Johanneke D., Porter, Emily, Szomolay, Barbara ORCID: https://orcid.org/0000-0002-5375-5533, Montoya, Maria, Hammond, John A., Miles, John J., Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Townsend, Alain, Bailey, Mick, Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369, Charleston, Bryan, Tchilian, Elma and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135
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| Jimenez, Rocio, Ikonomopoulou, Maria P., Lopez, J. Alejandro and Miles, John J. 2018. Immune drug discovery from venoms. Toxicon 141 , pp. 18-24. 10.1016/j.toxicon.2017.11.006 |
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Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Fuller, Anna, Dolton, Garry, Zervoudi, Efthalia, Legut, Mateusz, Miles, Kim, Blanchfield, Lori, Madura, Florian, Holland, Christopher J., Bulek, Anna M., Bridgeman, John S., Miles, John J., Schauenburg, Andrea J. A., Beck, Konrad ORCID: https://orcid.org/0000-0001-5098-9484, Evavold, Brian D., Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135
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Dual molecular mechanisms govern escape at immunodominant HLA A2-restricted HIV epitope.
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| Smallwood, Taylor B., Giacomin, Paul R., Loukas, Alex, Mulvenna, Jason P., Clark, Richard J. and Miles, John James 2017. Helminth immunomodulation in autoimmune disease. Frontiers in Immunology 10.3389/fimmu.2017.00453 |
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Blake, S. J., Dougall, W. C., Miles, John James, Teng, M. W. L. and Smyth, M. J.
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Molecular pathways: targeting CD96 and TIGIT for cancer immunotherapy.
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Laugel, Bruno, Lloyd, Angharad, Meermeier, Erin W., Crowther, Michael D., Connor, Thomas ORCID: https://orcid.org/0000-0003-2394-6504, Dolton, Garry Michael, Miles, John James, Burrows, Scott R., Gold, Marielle C., Lewinsohn, David M. and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135
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Engineering of isogenic cells deficient for MR1 with a CRISPR/Cas9 lentiviral system: tools to study microbial antigen processing and presentation to human MR1-restricted T cells.
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T-cell libraries allow simple parallel generation of multiple peptide-specific human T-cell clones.
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T cell cross-reactivity between a highly immunogenic EBV epitope and a self-peptide naturally presented by HLA-B*18:01+ cells.
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Rossjohn, Jamie ORCID: https://orcid.org/0000-0002-2020-7522, Gras, Stephanie, Miles, John James, Turner, Stephen J., Godfrey, Dale I. and McCluskey, James
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Antibody stabilization of peptide-MHC multimers reveals functional T cells bearing extremely low-affinity TCRs.
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| Lau, Lei Shong, Fernandez-Ruiz, Daniel, Mollard, Vanessa, Sturm, Angelika, Neller, Michelle A., Cozijnsen, Anton, Gregory, Julia L., Davey, Gayle M., Jones, Claerwen M., Lin, Yi-Hsuan, Haque, Ashraful, Engwerda, Christian R., Nie, Catherine Q., Hansen, Diana S., Murphy, Kenneth M., Papenfuss, Anthony T., Miles, John J., Burrows, Scott R., de Koning-Ward, Tania, McFadden, Geoffrey I., Carbone, Francis R., Crabb, Brendan S. and Heath, William R. 2014. CD8+ T cells from a novel T cell receptor transgenic mouse induce liver-stage immunity that can be boosted by blood-stage infection in rodent malaria. PLoS Pathogens 10 (5) , e1004135. 10.1371/journal.ppat.1004135 |
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| Burrows, Scott R. and Miles, John James 2013. Immune parameters to consider when choosing T-Cell receptors for therapy. Frontiers in Immunology 4 , 229. 10.3389/fimmu.2013.00229 |
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Patel, O., Kjer-Nielsen, L., Le Nours, J., Eckle, S., Birkinshaw, R., Beddoe, T., Corbett, A., Liu, L., Miles, John James, Meehan, B., Reantragoon, R., Sandoval-Romero, M., Sullivan, L., Brooks, A., Chen, Z., Fairlie, D., McCluskey, J. and Rossjohn, Jamie ORCID: https://orcid.org/0000-0002-2020-7522
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Advances in T-Cell Epitope Engineering.
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Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Edwards, Emily ORCID: https://orcid.org/0000-0002-0240-4370, Wynn, Katherine, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Miles, John James, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Ekeruche, Julia, Gostick, Emma, Adams, Katherine J., Skowera, Ania, Peakman, Mark, Wooldridge, Linda, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135
2010.
Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition.
The Journal of Immunology
185
(4)
, pp. 2600-2610.
10.4049/jimmunol.1000629
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Dibley, Michael, Li, Haijiang ORCID: https://orcid.org/0000-0001-6326-8133, Miles, John C and Rezgui, Yacine ORCID: https://orcid.org/0000-0002-5711-8400
2010.
The application of intelligent agency in a software model for buildings.
Presented at: EG-ICE 2010 - 17th International Workshop on Intelligent Computing in Engineering,
Nottingham, UK,
30 Jun - 2 Jul 2010.
Proceedings of The XVII Workshop for Intelligent Computing in Engineering.
Nottingham University Press,
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Miles, John James, Bulek, Anna Marta, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Gostick, Emma, Schauenburg, Andrea J. A., Dolton, Garry Michael, Venturi, Vanessa, Davenport, Miles P., Tan, Mai Ping, Burrows, Scott R., Wooldridge, Linda, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135
2010.
Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection.
PLoS Pathogens
6
(11)
, e1001198.
10.1371/journal.ppat.1001198
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Wooldridge, Linda, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Lissina, Anna, Edwards, Emily ORCID: https://orcid.org/0000-0002-0240-4370, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Ekeruche, Julia, Hewitt, R. E., Laugel, Bruno Frederic, Gostick, Emma, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Debets, R., Berrevoets, C., Miles, John James, Burrows, S. R., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135
2010.
MHC Class I molecules with superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs.
Journal of Immunology
184
(7)
, pp. 3357-3366.
10.4049/jimmunol.0902398
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Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Yuan, Fang, Rizkallah, Pierre ORCID: https://orcid.org/0000-0002-9290-0369, Miles, John James, Gostick, Emma, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Gao, George F., Jakobsen, Bent K. and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135
2009.
Germ line-governed recognition of a cancer epitope by an immunodominant human T-cell receptor.
Journal of Biological Chemistry
284
(40)
, 27281-27289.
10.1074/jbc.M109.022509
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Zhang, Yu, Kwan, Alan Shu Khen ORCID: https://orcid.org/0000-0003-4206-4435 and Miles, John James
2008.
Using generative representations for structural design.
Presented at: Intelligent Computing in Engineering 2008 Conference: 15th workshop of the European Group for Intelligent Computing in Engineering (EG-ICE),
Plymouth, UK,
2-4 July 2008.
Published in: Rafiq, Y., de Wilde, P. and Borthwick, M. eds.
Proceedings: Intelligent Computing in Engineering 2008 Conference.
Plymouth:
American Society of Civil Engineers (ASCE),
pp. 36-45.
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