Abdelfattah, Ali Mahmoud, Hughes-Davies, Antonia, Clayfield, Liam Daniel, Menendez-Gonzalez, Juan Bautista, Almotiri, Alhomidi, Alotaibi, Badi, Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976 and Rodrigues, Neil P ORCID: https://orcid.org/0000-0002-1925-7733
2021.
Gata2 haploinsufficiency promotes proliferation and functional decline of HSCs with myeloid bias during aging.
Blood Advances
5
(20)
, pp. 4285-4290.
10.1182/bloodadvances.2021004726
|
|
|
Almotiri, Alhomidi, Alzahrani, Hamed Ahmad A., Menendez-Gonzalez, Juan Bautista, Abdelfattah, Ali, Alotaibi, Badi, Saleh, Lubaid, Greene, Adelle, Georgiou, Mia R. F., Gibbs, Alex, Alsayari, Amani Salem, Taha, Sarab, Thomas, Leigh-Anne, Shah, Dhruv, Edkins, Sarah ORCID: https://orcid.org/0000-0003-0717-1972, Giles, Peter J. ORCID: https://orcid.org/0000-0003-3143-6854, Stemmler, Marc P., Brabletz, Simone, Brabletz, Thomas, Boyd, Ashleigh S., Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775 and Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733
2021.
Zeb1 modulates hematopoietic stem cell fates required for suppressing acute myeloid leukemia.
Journal of Clinical Investigation
131
(1)
, e129115.
10.1172/JCI129115
|
|
|
Arana Echarri, Ainhoa, Beresford, Mark, Campbell, John P., Jones, Robert H. ORCID: https://orcid.org/0000-0003-3576-9496, Butler, Rachel, Gollob, Kenneth J., Brum, Patricia C., Thompson, Dylan and Turner, James E.
2021.
A phenomic perspective on factors influencing breast cancer treatment: integrating aging and lifestyle in blood and tissue biomarker profiling.
Frontiers in Immunology
11
, 616188.
10.3389/fimmu.2020.616188
|
|
|
Castro, Jessica, Tornillo, Giusy, Ceada, Gerardo, Ramos-Neble, Beatriz, Bravo, Marlon, Ribo', Marc, Vilanova, Maria, Smalley, Matthew ORCID: https://orcid.org/0000-0001-9540-1146 and Benito, Antoni
2021.
A nuclear-directed ribonuclease variant targets cancer stem cells and inhibits migration and invasion of breast cancer cells.
Cancers
13
(17)
, 4350.
10.3390/cancers13174350
|
|
|
Davies, James A. ORCID: https://orcid.org/0000-0003-3569-4500, Marlow, Gareth ORCID: https://orcid.org/0000-0002-7608-9086, Uusi-Kerttula, Hanni K., Seaton, Gillian, Piggott, Luke, Badder, Luned M., Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Chester, John D. ORCID: https://orcid.org/0000-0002-7830-3840 and Parker, Alan L. ORCID: https://orcid.org/0000-0002-9302-1761
2021.
Efficient intravenous tumor targeting using the αvβ6 integrin-selective precision virotherapy Ad5NULL-A20.
Viruses
13
(5)
, 864.
10.3390/v13050864
|
|
|
Edmunds, Grace L., Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146, Beck, Sam, Errington, Rachel J. ORCID: https://orcid.org/0000-0002-8016-4376, Gould, Sara, Winter, Helen, Brodbelt, David and O'Neill, Dan
2021.
Dog breeds and body conformations with predisposition to osteosarcoma in the UK: a case-control study.
Canine Medicine and Genetics
8
, 2.
10.1186/s40575-021-00100-7
|
|
|
Gupta, Bhavana, Errington, Adam C. ORCID: https://orcid.org/0000-0002-2171-389X, Jimenez-Pascual, Ana, Eftychidis, Vasileios, Brabletz, Simone, Stemmler, Marc P., Brabletz, Thomas, Petrik, David ORCID: https://orcid.org/0000-0003-3026-0770 and Siebzehnrubl, Florian A. ORCID: https://orcid.org/0000-0001-8411-8775
2021.
The transcription factor ZEB1 regulates stem cell self-renewal and cell fate in the adult hippocampus.
Cell Reports
36
(8)
, 109588.
10.1016/j.celrep.2021.109588
|
|
|
Hill, William, Zaragkoulias, Andreas, Salvador-Barbero, Beatriz, Parfitt, Geraint ORCID: https://orcid.org/0000-0002-8704-7906, Alatsatianos, Markella, Padilha, Ana, Porazinski, Sean, Woolley, Thomas E. ORCID: https://orcid.org/0000-0001-6225-5365, Morton, Jennifer P., Sansom, Owen J. ORCID: https://orcid.org/0000-0001-9540-3010 and Hogan, Catherine ORCID: https://orcid.org/0000-0002-1012-0896
2021.
EPHA2-dependent outcompetition of KRASG12D mutant cells by wild-type neigbors in the adult pancreas.
Current Biology
31
(12)
, pp. 2550-2560.
10.1016/j.cub.2021.03.094
|
|
|
Jukes, Zoe, Freier, Anne, Glymenaki, Maria, Brown, Richard, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Want, Elizabeth, Vorkas, Panagiotis A. and Li, Jia V.
2021.
Lipid profiling of mouse intestinal organoids for studying APC mutations.
Bioscience Reports
41
(3)
, BSR20202915.
10.1042/BSR20202915
|
|
|
Kermanizadeh, Ali, Jacobsen, Nicklas Raus, Murphy, Fiona, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Zhang, Haiyuan and Møller, Peter
2021.
A review of the current state of nanomedicines for targeting and treatment of cancers - achievements and future challenges.
Advanced Therapeutics
4
(2)
, 2000186.
10.1002/adtp.202000186
|
|
|
Lawson, Hannah, Sepulveda, Catarina, van de Latemaat, Louie N., Durko, Jozef, Barile, Melania, Tavosanis, Andrea, Georges, Elise, Shmakova, Alena, Timms, Penny, Carter, Roderick N., Allen, Lewis, Campos, Joana, Vukovic, Milica, Guitart, Amelie V., Giles, Peter ORCID: https://orcid.org/0000-0003-3143-6854, O'Shea, Marie, Vernimmen, Douglas, Morton, Nicholas M., Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733, Gottgens, Berthold, Schofield, Christopher J., Lengeling, Andreas, O'Carroll, Donal and Kranc, Kamil R.
2021.
JMJD6 promotes self-renewal and regenerative capacity of hematopoietic stem cells.
Blood Advances
5
(3)
, pp. 889-899.
10.1182/bloodadvances.2020002702
|
|
|
Lawson, Hannah, van de Lagemaat, Louie N., Barile, Melania, Tavosanis, Andrea, Durko, Jozef, Villacreces, Arnaud, Bellani, Aarushi, Mapperley, Christopher, Georges, Elise, Martins-Costa, Catarina, Sepulveda, Catarina, Allen, Lewis, Campos, Joana, Campbell, Kirsteen J., O'Carroll, Donal, Gottgens, Berthold, Cory, Suzanne, Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733, Guitart, Amelie V. and Kranc, Kamil R.
2021.
CITED2 coordinates key haematopoietic regulatory pathways to maintain the HSC pool in both steady-state haematopoiesis and transplantation.
Stem Cell Reports
16
(11)
, pp. 2784-2797.
10.1016/j.stemcr.2021.10.001
|
|
|
Mian, Syed A., Dos Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X and Bonnet, Dominique
2021.
Advances in human immune system mouse models for studying human hematopoiesis and cancer immunotherapy.
Frontiers in Immunology
11
, 619236.
10.3389/fimmu.2020.619236
|
|
|
Moss, Joe W. E. ORCID: https://orcid.org/0000-0002-1866-9752, Williams, Jessica O., Al-Ahmadi, Wijdan, O'Morain, Victoria, Chan, Yee-Hung, Hughes, Timothy R. ORCID: https://orcid.org/0000-0003-2348-3490, Menendez-Gonzalez, Juan B., Almotiri, Alhomidi, Plummer, Sue F., Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733, Michael, D. R. and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578
2021.
Protective effects of a unique combination of nutritionally active ingredients on risk factors and gene expression associated with atherosclerosis in C57BL/6J mice fed a high fat diet.
Food and Function
12
(8)
, pp. 3657-3671.
10.1039/D0FO02867C
|
|
|
O'Morain, Victoria L., Chan, Yee-Hung, Williams, Jessica O., Alotibi, Reem, Alahmadi, Alaa, Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733, Plummer, Sue F., Hughes, Timothy R., Michael, Daryn R. and Ramji, Dipak P. ORCID: https://orcid.org/0000-0002-6419-5578
2021.
The Lab4P consortium of probiotics attenuates atherosclerosis in LDL receptor deficient mice fed a high fat diet and causes plaque stabilization by inhibiting inflammation and several pro-atherogenic processes.
Molecular Nutrition & Food Research
65
(17)
, 2100214.
10.1002/mnfr.202100214
|
|
|
Ordonez, Liliana D., Melchor, Lorenzo, Greenow, Kirsty R., Kendrick, Howard, Tornillo, Giusy, Bradford, James, Giles, Peter ORCID: https://orcid.org/0000-0003-3143-6854 and Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146
2021.
Reproductive history determines ErbB2 locus amplification, WNT signalling and tumour phenotype in a murine breast cancer model.
Disease Models and Mechanisms
14
(5)
, dmm048736.
10.1242/dmm.048736
|
|
|
Rastogi, Namrata, Baker, Sarah ORCID: https://orcid.org/0000-0002-7474-9757, Man, Stephen ORCID: https://orcid.org/0000-0001-9103-1686, Uger, Robert A., Wong, Mark, Coles, Steve J., Hodges, Marie, Gilkes, Amanda, Knapper, Steven ORCID: https://orcid.org/0000-0002-6405-4441, Darley, Richard ORCID: https://orcid.org/0000-0003-0879-0724 and Tonks, Alex ORCID: https://orcid.org/0000-0002-6073-4976
2021.
Use of an anti-CD200 blocking antibody improves immune responses to AML in vitro and in vivo.
British Journal of Haematology
193
(1)
, pp. 155-159.
10.1111/bjh.17125
|
|
|
Seligmann, Jenny F., Fisher, David J., Brown, Louise C., Adams, Richard A. ORCID: https://orcid.org/0000-0003-3915-7243, Graham, Janet, Quirke, Philip, Richman, Susan D., Butler, Rachel, Domingo, Enric, Blake, Andrew, Yates, Emma, Braun, Michael, Collinson, Fiona, Jones, Rob ORCID: https://orcid.org/0000-0003-3576-9496, Brown, Ewan, de Winton, Emma, Humphrey, Timothy C., Parmar, Mahesh, Kaplan, Richard, Wilson, Richard H., Seymour, Matthew and Maughan, Timothy S.
2021.
Inhibition of WEE1 is effective in TP53- and RAS-mutant metastatic colorectal cancer: a randomized trial (FOCUS4-C) comparing adavosertib (AZD1775) with active monitoring.
Journal of Clinical Oncology
39
(33)
, pp. 3705-3715.
10.1200/JCO.21.01435
|
|
|
Soukupova, Jitka, Bordoni, Cinzia, Turnham, Daniel J. ORCID: https://orcid.org/0000-0002-2540-7363, Yang, William W., Seaton, Gillian, Gruca, Aleksandra, French, Rhiannon, Lee, Kok Yung, Varnava, Athina, Piggott, Luke, Clarkson, Richard W. E. ORCID: https://orcid.org/0000-0001-7389-8673, Westwell, Andrew D. ORCID: https://orcid.org/0000-0002-5166-9236 and Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419
2021.
The discovery of a novel anti-metastatic Bcl3 inhibitor.
Molecular Cancer Therapeutics
10
(5)
, pp. 775-786.
10.1158/1535-7163.MCT-20-0283
|
|
|
Stott, Katie J., Phillips, Bethan, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 and May, Stephanie
2021.
Recent advancements in the exploitation of the gut microbiome in the diagnosis and treatment of colorectal cancer.
Bioscience Reports
41
(7)
, BSR20204113.
10.1042/BSR20204113
|
|
|
Tran, Bang Manh, Flanagan, Dustin James, Phesse, Toby James ORCID: https://orcid.org/0000-0001-9568-4916, Vincan, Elizabeth and Phesse, Toby
2021.
Frizzled7 activates β-catenin-dependent and β-catenin-independent Wnt signalling pathways during developmental morphogenesis: implications for therapeutic targeting in colorectal cancer.
Schulte, Gunnar and Kozielewicz, Pawel, eds.
Handbook of Experimental Pharmacology 269: Pharmacology of the WNT Signaling System,
Vol. 269.
Handbook of Experimental Pharmacology,
vol. 269.
Springer,
pp. 251-278.
(10.1007/164_2021_524)
|
|