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Number of items: 35.

Badder, Luned 2017. Developing stem-cell containing organoids as a pre-clinical model for colorectal cancer therapeutics. PhD Thesis, Cardiff University.
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Berenjeno, Inma M., Piñeiro, Roberto, Castillo, Sandra D., Pearce, Wayne, McGranahan, Nicholas, Dewhurst, Sally M., Meniel, Valerie, Birkbak, Nicolai J., Lau, Evelyn, Sansregret, Laurent, Morelli, Daniele, Kanu, Nnennaya, Srinivas, Shankar, Graupera, Mariona, Parker, Victoria E. R., Montgomery, Karen G., Moniz, Larissa S., Scudamore, Cheryl L., Phillips, Wayne A., Semple, Robert K., Clarke, Alan, Swanton, Charles and Vanhaesebroeck, Bart 2017. Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling. Nature Communications 8 (1) , 1773. 10.1038/s41467-017-02002-4
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Carotenuto, Pietro, Fassan, Matteo, Pandolfo, Rosantony, Lampis, Andrea, Vicentini, Caterina, Cascione, Luciano, Paulus-Hock, Viola, Boulter, Luke, Guest, Rachel, Quagliata, Luca, Hahne, Jens Claus, Ridgway, Rachel, Jamieson, Tam, Athineos, Dimitris, Veronese, Angelo, Visone, Rosa, Murgia, Claudio, Ferrari, Giulia, Guzzardo, Vincenza, Evans, Thomas Ronald Jeffry, MacLeod, Martin, Feng, Gui Ji, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963, Negrini, Massimo, Forbes, Stuart J, Terracciano, Luigi, Scarpa, Aldo, Patel, Tushar, Valeri, Nicola, Workman, Paul, Sansom, Owen and Braconi, Chiara 2017. Wnt signalling modulates transcribed-ultraconserved regions in hepatobiliary cancers. Gut 66 (7) , pp. 1268-1277. 10.1136/gutjnl-2016-312278
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Chen, Hung-Chang, Joalland, Noémie, Bridgeman, John S, Alchami, Fouad S, Jarry, Ulrich, Khan, Mohd Wajid A, Piggott, Luke, Shanneik, Yasmin, Li, Jianqiang, Herold, Marco J, Herrmann, Thomas, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Gallimore, Awen M. ORCID: https://orcid.org/0000-0001-6675-7004, Clarkson, Richard W. ORCID: https://orcid.org/0000-0001-7389-8673, Scotet, Emmanuel, Moser, Bernhard ORCID: https://orcid.org/0000-0002-4354-4572 and Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348 2017. Synergistic targeting of breast cancer stem-like cells by human γδ T cells and CD8+ T cells. Immunology and Cell Biology 95 (7) , pp. 620-629. 10.1038/icb.2017.21
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Chiang, Kelly, Zielinska, Agnieszka E., Shaaban, Abeer M., Sanchez-Bailon, Maria Pilar, Jarrold, James, Clarke, Thomas L, Zhang, Jingxian, Francis, Adele, Jones, Louise J., Smith, Sally, Barbash, Olena, Guccione, Ernesto, Farnie, Gillian, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 and Davies, Clare C. 2017. PRMT5 is a critical regulator of breast cancer stem cell function via Histone Methylation and FOXP1 expression. Cell Reports 21 (12) , pp. 3498-3513. 10.1016/j.celrep.2017.11.096
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Colbeck, Emily J., Jones, Emma, Hindley, James P., Smart, Kathryn, Schulz, Ralph, Browne, Molly, Cutting, Scott, Williams, Anwen ORCID: https://orcid.org/0000-0001-6118-020X, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567, Ware, Carl F., Ager, Ann and Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 2017. Treg depletion licenses T cell-driven HEV neogenesis and promotes tumor destruction. Cancer Immunology Research 5 (11) , pp. 1005-1015. 10.1158/2326-6066.CIR-17-0131
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Dietrich, Laura, Rathmer, Bernd, Ewan, Kenneth ORCID: https://orcid.org/0000-0001-6622-9009, Bange, Tanja, Stefan, Heinrichs, Dale, Trevor Clive ORCID: https://orcid.org/0000-0002-4880-9963, Dennis, Schade and Grossmann, Tom N. 2017. Cell permeable stapled peptide inhibitor of Wnt signaling that targets β-catenin protein‒protein interactions. Cell Chemical Biology 24 (8) , pp. 958-968. 10.1016/j.chembiol.2017.06.013
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Flanagan, Dustin J, Vincan, Elizabeth and Phesse, Toby J. ORCID: https://orcid.org/0000-0001-9568-4916 2017. Winding back Wnt signalling: potential therapeutic targets for treating gastric cancers. British Journal of Pharmacology 174 (24) , pp. 4666-4683. 10.1111/bph.13890
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Flanagan, Dustin J., Barker, Nick, Nowell, Cameron, Clevers, Hans, Ernst, Matthias, Phesse, Toby J. ORCID: https://orcid.org/0000-0001-9568-4916 and Vincan, Elizabeth 2017. Loss of the Wnt receptor frizzled 7 in the mouse gastric epithelium is deleterious and triggers rapid repopulation in vivo. Disease Models and Mechanisms 10 (8) , pp. 971-980. 10.1242/dmm.029876
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Garcia Martin, Isabel, Janssen, A.B., Jones, Robert ORCID: https://orcid.org/0000-0003-3576-9496, Grimstead, Julia W., Penketh, Richard J. A., Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467 and John, Rosalind M. ORCID: https://orcid.org/0000-0002-3827-7617 2017. Telomere length heterogeneity in placenta revealed with high-resolution telomere length analysis. Placenta 59 , pp. 61-68. 10.1016/j.placenta.2017.09.007
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Guitart, Amelie V, Panagopoulou, Theano I, Villacreces, Arnaud, Vukovic, Milica, Sepulveda, Catarina, Allen, Lewis, Carter, Roderick N, Lagemaat, Louie N van de, Morgan, Marcos, Giles, Peter, Sas, Zuzanna, Gonzalez, Marta Vila, Lawson, Hannah, Paris, Jasmin, Edwards-Hicks, Joy, Schaak, Katrin, Subramani, Chithra, Gezer, Deniz, Armesilla-Diaz, Alejandro, Wills, Jimi Carlo, Easterbrook, Aaron, Coman, David, Wai, Chi, So, Eric, O'Carroll, Donal, Vernimmen, Douglas, Rodrigues, Neil ORCID: https://orcid.org/0000-0002-1925-7733, Pollard, Patrick J, Morton, Nicholas M, Finch, Andrew and Kranc, Kamil R 2017. Fumarate hydratase is a critical regulator of hematopoietic stem cell functions. Journal of Experimental Medicine 214 (3) , -. 10.1084/jem.20161087
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Helft, Julie, Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X, van der Veen, Annemarthe G., Chakravarty, Probir, Bonnet, Dominique and Reis e Sousa, Caetano 2017. Dendritic cell lineage potential in human early hematopoietic progenitors. Cell Reports 20 (3) , pp. 529-537. 10.1016/j.celrep.2017.06.075
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Hwang, Ho Sik, Parfitt, Geraint J. ORCID: https://orcid.org/0000-0002-8704-7906, Brown, Donald J. and Jester, James V. 2017. Meibocyte differentiation and renewal: Insights into novel mechanisms of meibomian gland dysfunction (MGD). Experimental Eye Research 163 , pp. 37-45. 10.1016/j.exer.2017.02.008
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Jefferies, Matthew T., Cox, Adam C., Shorning, Boris Y., Meniel, Valerie, Griffiths, David, Kynaston, Howard G. ORCID: https://orcid.org/0000-0003-1902-9930, Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 and Clarke, Alan R. 2017. PTEN loss and activation of K-RAS and β-catenin cooperate to accelerate prostate tumourigenesis. Journal of Pathology 243 (4) , pp. 442-456. 10.1002/path.4977
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Kay, Sophie K., Harrington, Heather A., Shepherd, Sarah, Brennan, Keith, Dale, Trevor ORCID: https://orcid.org/0000-0002-4880-9963, Osborne, James M., Gavaghan, David J. and Byrne, Helen M. 2017. The role of the Hes1 crosstalk hub in Notch-Wnt interactions of the intestinal crypt. PLoS Computational Biology 13 (2) , e1005400. 10.1371/journal.pcbi.1005400
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Konstantinou, Maria 2017. Characterising In-111-anti-γH2AX-TAT in targeting the DNA damage signal associated with Wnt activated colorectal cancer. PhD Thesis, Cardiff University.
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Lampreia, Fabio Pereira, Carmelo, Joana Gonçalves and Anjos-Afonso, Fernando ORCID: https://orcid.org/0000-0003-4392-488X 2017. Notch signaling in the regulation of hematopoietic stem cell. Current Stem Cell Reports 10.1007/s40778-017-0090-8
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Lanfredini, Simone ORCID: https://orcid.org/0000-0002-3160-5120, Olivero, Carlotta ORCID: https://orcid.org/0000-0002-8961-6703, Borgogna, Cinzia, Calati, Federica, Powell, Kathryn, Davies, Kelli-Jo, De Andrea, Marco, Harries, Sarah, Tang, Hiu, Pfister, Herbert, Gariglio, Marisa and Patel, Girish K 2017. HPV8 field cancerization in a transgenic mouse model is due to Lrig1+Keratinocyte stem cell expansion. Journal of Investigative Dermatology 137 (10) , pp. 2208-2216. 10.1016/j.jid.2017.04.039
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Liu, David S., Duong, Cuong P., Haupt, Sue, Montgomery, Karen G., House, Colin M., Azar, Walid J., Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843, Fisher, Oliver M., Read, Matthew, Guerra, Glen R., Haupt, Ygal, Cullinane, Carleen, Wiman, Klas G., Abrahmsen, Lars, Phillips, Wayne A. and Clemons, Nicholas J. 2017. Inhibiting the system xC-/glutathione axis selectively targets cancers with mutant-p53 accumulation. Nature Communications 8 , 14844. 10.1038/ncomms14844
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Martin, Ana Carolina B.M., Fuzer, Angelina M., Becceneri, Amanda B., da Silva, James Almada, Tomasin, Rebeka, Denoyer, Delphine, Kim, Soo-Hyun, McIntyre, Katherine A., Pearson, Helen B. ORCID: https://orcid.org/0000-0002-3284-0843, Yeo, Belinda, Nagpal, Aadya, Ling, Xiawei, Selistre-de-Araújo, Heloisa S., Vieira, Paulo Cézar, Cominetti, Marcia R. and Pouliot, Normand 2017. [10]-gingerol induces apoptosis and inhibits metastatic dissemination of triple negative breast cancer in vivo. Oncotarget 8 (42) , pp. 72260-72271. 10.18632/oncotarget.20139
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May, Stephanie, Evans, Samantha and Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196 2017. Organoids, organs-on-chips and other systems, and microbiota. Emerging Topics in Life Sciences 1 (4) , pp. 385-400. 10.1042/ETLS20170047
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Menendez Gonzalez, Juan Bautista 2017. Exploring the role of GATA2 in normal and malignant haematopoiesis. PhD Thesis, Cardiff University.
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Mohamed, Noha-Ehssan 2017. Characterizing the roles of APC2 protein in ovarian homeostasis and tumourigenesis. PhD Thesis, Cardiff University.
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Phesse, Toby J. ORCID: https://orcid.org/0000-0001-9568-4916 and Sansom, Owen J. 2017. Lgr5 joins the club of gastric stem cell markers in the corpus. Nature Cell Biology 19 (7) , pp. 752-754. 10.1038/ncb3567
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Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916, Marsh Durban, Victoria and Sansom, Owen J. 2017. Defining key concepts of intestinal and epithelial cancer biology through the use of mouse models. Carcinogenesis 38 (10) , pp. 953-965. 10.1093/carcin/bgx080
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Planells-Palop, Vicente, Hazazi, Ali, Feichtinger, Julia, Jezkova, Jana, Thallinger, Gerhard, Alsiwiehri, Naif O., Almutairi, Mikhlid, Parry, Lee ORCID: https://orcid.org/0000-0002-4467-9196, Wakeman, Jane A. and McFarlane, Ramsay J. 2017. Human germ/stem cell-specific gene TEX19 influences cancer cell proliferation and cancer prognosis. Molecular Cancer 16 , 84. 10.1186/s12943-017-0653-4
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Portero Migueles, Rosa, Shaw, Louise, Rodrigues, Neil P. ORCID: https://orcid.org/0000-0002-1925-7733, May, Gillian, Henseleit, Korinna, Anderson, Kathryn G. V., Goker, Hakan, Jones, C. Michael, de Bruijn, Marella F. T. R., Brickman, Joshua M. and Enver, Tariq 2017. Transcriptional regulation of Hhex in hematopoiesis and hematopoietic stem cell ontogeny. Developmental Biology 424 (2) , pp. 236-245. 10.1016/j.ydbio.2016.12.021
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Roy, Ananya, Attarha, Sanaz, Weishaupt, Holger, Edqvist, Per-Henrik, Swartling, Fredrik J., Bergqvist, Michael, Siebzehnrubl, Florian ORCID: https://orcid.org/0000-0001-8411-8775, Smits, Anja, Pontén, Fredrik and Tchougounova, Elena 2017. Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression. Oncotarget 8 , pp. 24815-24827. 10.18632/oncotarget.15820
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Schwab, Renate H.M., Amin, Nancy, Flanagan, Dustin J., Johanson, Timothy M., Phesse, Toby ORCID: https://orcid.org/0000-0001-9568-4916 and Vincan, Elizabeth 2017. Wnt is necessary for mesenchymal to epithelial transition in colorectal cancer cells. Developmental Dynamics 247 (3) , pp. 521-530. 10.1002/dvdy.24527
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Scurr, Martin ORCID: https://orcid.org/0000-0002-4120-0688, Pembroke, Tom, Adams, Richard ORCID: https://orcid.org/0000-0003-3915-7243, Blount, Daniel, Brewster, Alison, Gwynne, Sarah, Harrop, Richard, Jones, Robert ORCID: https://orcid.org/0000-0003-3576-9496, Hills, Robert ORCID: https://orcid.org/0000-0003-0166-0062, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2017. MVA-5T4 immunotherapy and low-dose cyclophosphamide for advanced colorectal cancer (TaCTiCC): An open-label, randomized phase I/II trial. Journal of Clinical Oncology 35 (7) , p. 154. 10.1200/JCO.2017.35.7_suppl.154
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Scurr, Martin J ORCID: https://orcid.org/0000-0002-4120-0688, Pembroke, Tom, Bloom, Anja, Roberts, David J, Thomson, Amanda, Smart, Kathryn, Bridgeman, Hayley, Adams, Richard A ORCID: https://orcid.org/0000-0003-3915-7243, Brewster, Alison E, Jones, Robert ORCID: https://orcid.org/0000-0003-3576-9496, Gwynne, Sarah, Blount, Daniel, Harrop, Richard, Hills, Robert ORCID: https://orcid.org/0000-0003-0166-0062, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2017. Low-dose cyclophosphamide induces anti-tumor T-cell responses which associate with survival in metastatic colorectal cancer. Clinical Cancer Research , clincanres.0895.2017. 10.1158/1078-0432.CCR-17-0895
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Scurr, Martin ORCID: https://orcid.org/0000-0002-4120-0688, Pembroke, Tom ORCID: https://orcid.org/0000-0002-2600-2034, Bloom, Anja, Roberts, David, Thomson, Amanda, Smart, Kathryn, Bridgeman, Hayley, Adams, Richard ORCID: https://orcid.org/0000-0003-3915-7243, Brewster, Alison, Jones, Robert ORCID: https://orcid.org/0000-0003-3576-9496, Gwynne, Sarah, Blount, Daniel, Harrop, Richard, Wright, Melissa ORCID: https://orcid.org/0000-0002-1011-4795, Hills, Robert ORCID: https://orcid.org/0000-0003-0166-0062, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004 and Godkin, Andrew ORCID: https://orcid.org/0000-0002-1910-7567 2017. Effect of modified vaccinia Ankara–5T4 and low-dose cyclophosphamide on antitumor immunity in metastatic colorectal cancer: A randomized clinical trial. JAMA Oncology 3 (10) , e172579. 10.1001/jamaoncol.2017.2579
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Soady, Kelly J., Tornillo, Giusy, Kendrick, Howard, Meniel, Valerie, Olijnyk-Dallis, Daria, Morris, Joanna S., Stein, Torstein, Gusterson, Barry A., Isacke, Clare M. and Smalley, Matthew J. ORCID: https://orcid.org/0000-0001-9540-1146 2017. Receptor protein tyrosine phosphatase PTPRB negatively regulates FGF2-dependent branching morphogenesis. Development 144 (20) , pp. 3777-3788. 10.1242/dev.149120
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Tang, Hiu Kwan Carolyn, Lee, Doreen Yin Hui, Thompson, Ian, Ingram, John R. ORCID: https://orcid.org/0000-0002-5257-1142, Stone, Natalie and Patel, Girish K. 2017. Delayed and localized pemphigus vulgaris after breast cancer radiotherapy. The Breast Journal 23 (6) , pp. 747-749. 10.1111/tbj.12910
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Yeo, Syn Kok, French, Rhiannon, Filomena, Spada and Clarkson, Richard ORCID: https://orcid.org/0000-0001-7389-8673 2017. Opposing roles of Nfkb2 gene products p100 and p52 in the regulation of breast cancer stem cells. Breast Cancer Research and Treatment 162 (3) , pp. 465-477. 10.1007/s10549-017-4149-0
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This list was generated on Sat Nov 29 10:16:07 2025 GMT.


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