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Number of items: 145.

Article

Abdelouahab, Nassima and Heard, Charles Martin

2008. Dermal and transcutaneous delivery of the major glycoside constituents of Harpagophytum procumbens (Devil's Claw) in vitro. Planta Medica 74 (5) , pp. 527-531. 10.1055/s-2008/1074500

Abdelouahab, Nassima and Heard, Charles Martin

2008. Effect of the major glycosides of Harpagophytum procumbens (Devil's Claw) on epidermal cyclooxygenase-2 (COX-2) in vitro. Journal of Natural Products 71 (5) , pp. 746-749. 10.1021/np070204u

Abdulmajed, K. and Heard, Charles Martin

2008. Topical delivery of retinyl ascorbate. Skin Pharmacology and Physiology 21 (1) , pp. 46-49. 10.1159/000111135

Adak, Rina, McGuigan, Christopher

, Snoeck, R., Andrei, G., Balzarini, J., Gorovits, E., Chang, C., Ames, B., Liu, Y. and Vernachio, J. 2008. Design and synthesis of novel non-nucleoside anti-HCMV agents [Abstract]. Antiviral Research 78 (2) , A52. 10.1016/j.antiviral.2008.01.107

Aiello, Stefania, Wells, Geoffrey, Stone, Erica L., Kadri, Hachemi, Bazzi, Rana, Bell, David R., Stevens, Malcolm F. G., Matthews, Charles S., Bradshaw, Tracey D. and Westwell, Andrew

2008. Synthesis and biological properties of benzothiazole, benzoxazole, and chromen-4-one analogues of the potent antitumor agent 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (PMX 610, NSC 721648). Journal of Medicinal Chemistry 51 (16) , pp. 5135-5139. 10.1021/jm800418z

Allen, Benjamin P. C., Nederkoorn, P. H. J., Timmerman, H., Timms, D., Broadley, Kenneth John

and Davies, Robin H. 2008. Monocation-driven proton transfer relays within G protein-coupled receptors of the rhodopsin class and the GTP synthase mechanism. Journal of Molecular Structure THEOCHEM 859 (1-3) , pp. 51-68. 10.1016/j.theochem.2008.03.011

Aslan, K., Previte, M. J. R., Zhang, Y. X., Gallagher, T., Baillie, Les

and Geddes, C. D. 2008. Extraction and detection of DNA from Bacillus anthracis spores and the vegetative cells within 1 min. Analytical Chemistry (including News & Features) 80 (11) , pp. 4125-4132. 10.1021/ac800519r

Bagley, Mark Christopher, Davis, Terence

, Dix, M. C., Murziani, Paola G. S., Rokicki, Michal Jaroslaw and Kipling, David Glyn 2008. Microwave-assisted synthesis of 5-aminopyrazol-4-yl ketones and the p38(MAPK) inhibitor RO3201195 for study in Werner syndrome cells. Bioorganic & Medicinal Chemistry Letters 18 (13) , pp. 3745-3748. 10.1016/j.bmcl.2008.05.037

Baillie, Les

, Rodriguez, Ana L., Moore, Stephen, Atkins, Helen S., Feng, Chiguang, Nataro, James P. and Pasetti, Marcela F. 2008. Towards a human oral vaccine for anthrax: the utility of a Salmonella Typhi Ty21a-based prime-boost immunization strategy. Vaccine 26 (48) , pp. 6083-6091. 10.1016/j.vaccine.2008.09.010

Basra, M. K. A., Edmunds, O., Salek, Mir-saeed and Finlay, Andrew Yule

2008. Measurement of family impact of skin disease: further validation of the Family Dermatology Life Quality Index (FDLQI). Journal of the European Academy of Dermatology and Venereology 22 (7) , pp. 813-821. 10.1111/j.1468-3083.2008.02593.x

Basra, M. K. A., Fenech, R., Gatt, R. M., Salek, Sam and Finlay, Andrew Yule

2008. The Dermatology Life Quality Index 1994-2007: a comprehensive review of validation data and clinical results. British Journal of Dermatology 159 (5) , pp. 997-1035. 10.1111/j.1365-2133.2008.08832.x

Baxter, Gary Francis

and Burley, Dwaine Simon 2008. Reperfusion and calculated RISKs: pharmacological postconditioning of human myocardium. British Journal of Pharmacology 153 (1) , pp. 1-3. 10.1038/sj.bjp.0707498

Bensmail, Abdelwahab, Hutcheson, Iain Robert, Giles, M., Gee, Julia Margaret Wendy

and Nicholson, Robert Ian 2008. Loss of oestrogen receptor alpha in long-term antioestrogen-resistant cells: reversal by a c-src inhibitor [Abstract]. Breast Cancer Research 10 (S2) , O3. 10.1186/bcr1883

Birchall, James Caradoc

, Jones, Brian and Morrissey, A. 2008. A comparison of the puncturing properties of gelatin and hypromellose capsules for use in dry powder inhalers. Drug Development and Industrial Pharmacy 34 (8) , pp. 870-876. 10.1080/03639040801928903

Borley, Annabel Catherine, Hiscox, Stephen Edward

, Gee, Julia Margaret Wendy

, Smith, Chris, Shaw, Victoria, Barrett-Lee, Peter and Nicholson, Robert Ian 2008. Anti-oestrogens but not oestrogen deprivation promote cellular invasion in intercellular adhesion-deficient breast cancer cells. Breast Cancer Research 10 (6) , R103. 10.1186/bcr2206

Bradshaw, B., Evans, P., Fletcher, J., Lee, A. T. L., Mwashimba, P. G., Oehlrich, D., Thomas, E. J., Davies, R. H., Allen, B. C. P., Broadley, Kenneth John

, Hamrouni, A. and Escargueil, C. 2008. Synthesis of 5-hydroxy-2,3,4,5-tetrahydro-[1H]-2-benzazepin-4-ones: selective antagonists of muscarinic (M-3) receptors. Organic & Biomolecular Chemistry 6 (12) , pp. 2138-2157. 10.1039/b801206g

Brahemi, Ghali, Fiasella, A., Brancale, Andrea

, Westwell, Andrew

and Burger, A. 2008. Design and synthesis of BCA2 inhibitors. EJC Supplements 6 (12) , p. 44.

Brancale, Andrea

, Vlachaki, Chrisanthy and Vlachakis, Dimitrios 2008. Molecular modelling study of the 3D structure of the bovine viral diarrhea virus (BVDV) helicase. In silico Biology 8 (5) , pp. 461-469.

Brancale, Andrea

, Vlachakiis, Dimitros, Kandil, Sahar, Biondaro, Sonia, Berry, Colin

and Neyts, Johan 2008. Discovery of a novel HCV helicase inhibitor by a de novo drug design approach. Antiviral Research 78 (2) , A22. 10.1016/j.antiviral.2008.01.030

Burley, Dwaine, George, Christopher, Wann, Kenneth Taylor and Baxter, Gary

2008. Evidence for serca and BKCa activation in BNP protection of reperfused myocardium [Abstract]. Journal of Molecular and Cellular Cardiology 44 (4) , p. 717. 10.1016/j.yjmcc.2008.02.015

Campbell, Lee, Jasani, Bharat, Edwards, K., Gumbleton, Mark

and Griffiths, David Francis Rees 2008. Combined expression of caveolin-1 and an activated AKT/mTOR pathway predicts reduced disease-free survival in clinically confined renal cell carcinoma. British Journal of Cancer 98 (5) , pp. 931-940. 10.1038/sj.bjc.6604243

Campbell, Lee, Jasani, Bharat, Gumbleton, Mark

, Edwards, K. and Griffiths, D. F. 2008. Expression of 4EBP1 is an influential prognostic covariate in renal cell carcinoma [Abstract]. Modern Pathology 21 (1s) , 150A. 10.1038/sj.modpathol.3801035

Castell, Oliver Kieran

, Allender, Christopher John and Barrow, David Anthony

2008. Continuous molecular enrichment in microfluidic systems. Lab on a Chip 8 (7) , pp. 1031-1033. 10.1039/b800521d

Coles, Barbara, Wilton, L. A. K., Good, Mark Andrew

, Chapman, P. F. and Wann, Kenneth Taylor 2008. Potassium channels in hippocampal neurones are absent in a transgenic but not in a chemical model of Alzheimer's disease. Brain Research 1190 , pp. 1-14. 10.1016/j.brainres.2007.10.071

Cosslett, Allan George

2008. Basic requirements: making total parenteral nutrition complete. Ejhp Practice 14 (2) , pp. 85-86.

Davies, Emily, Patel, C., Salek, Mir-saeed and Finlay, Andrew Yule

2008. Does ad hoc quality-of-life discussion in inflammatory skin disease consultations reflect standardized patient-reported outcomes? Clinical and Experimental Dermatology 33 (1) , pp. 16-21. 10.1111/j.1365-2230.2007.02557.x

Davison, Zoe, Dutkowski, Carol Mary, Gee, Julia Margaret Wendy

, Nicholson, Robert Ian and Heard, Charles Martin

2008. In vitro effects on MCF-7 breast cancer cells of signal transduction inhibitor/tamoxifen/eicosapentaenoic acid combinations and their simultaneous delivery across skin. Pharmaceutical Research 25 (11) , pp. 2516-2525. 10.1007/s11095-008-9665-5

Derudas, Marco, McGuigan, Christopher

, Brancale, Andrea

, Bugert, Joachim Jakob

, Andrei, G., Snoeck, R. and Balzarini, J. 2008. Design, synthesis and biological evaluation of novel acyclovir ProTides. Antiviral Research 78 (2) , A55-A56. 10.1016/j.antiviral.2008.01.116

Derudas, Marco, McGuigan, Christopher

, Brancale, Andrea

, Neyts, J. and Balzarini, J. 2008. Application of the phosphoramidate protide approach to the antiviral drug ribavirin. Antiviral Research 78 (2) , 55. 10.1016/j.antiviral.2008.01.115

Deslandes, P, Thomas, A., Blackmore, Eve Elizabeth and Sewell, Robert David Edmund 2008. Aripiprazole: 6-month outcomes in a retrospective naturalistic study. International Journal of Psychiatry in Clinical Practice 12 (4) , pp. 243-246. 10.1080/13651500801993241

Deslandes, P., Thomas, A., Lewis, A. and Sewell, Robert David Edmund 2008. Risperidone long acting injection: 2 year outcomes in a naturalistic study. European Neuropsychopharmacology 18 (S4) , S411-S412.

Dhippayom, T. and Walker, Roger 2008. Impact of the reduction of the prescription charge in Wales on the prescribing of non-sedating antihistamines in primary care. Health Policy 87 (3) , pp. 309-315. 10.1016/j.healthpol.2008.01.006

Eadala, Praveen, Waud, J. P., Matthews, Stephanie Beatrix, Green, John Trevor and Campbell, Anthony Keith 2008. Lactose intolerance and inflammatory bowel disease [Abstract]. Gut 57 (S1) , A115-A115.

Elgorashi, Abubakr S., Heard, Charles Martin

, Niazy, Esmail M., Noureldin, Osman H. and Pugh, William John 2008. Transdermal delivery enhancement of haloperidol from gel formulations by 1,8-cineole. Journal of Pharmacy and Pharmacology 60 (6) , pp. 689-692. 10.1211/jpp.60.6.0002

Fernandez-Rodriguez, Sofia, Ford, William Richard

, Broadley, Kenneth John

and Kidd, Emma Jane

2008. Establishing the phenotype in novel acute and chronic murine models of allergic asthma. International Immunopharmacology 8 (5) , pp. 756-763. 10.1016/j.intimp.2008.01.025

French, D. P. and James, Delyth H. 2008. Reasons for the use of mild analgesics among English students. Pharmacy World & Science 30 (1) , pp. 79-85. 10.1007/s11096-007-9146-7

Gomaa, Mohamed Sayed, Armstrong, Jane L., Bobillon, Beatrice, Veal, Gareth J., Brancale, Andrea

, Redfern, Christopher P.F. and Simons, Claire

2008. Novel azolyl-(phenylmethyl)]aryl/heteroarylamines: Potent CYP26 inhibitors and enhancers of all-trans retinoic acid activity in neuroblastoma cells. Bioorganic & Medicinal Chemistry 16 (17) , pp. 8301-8313. 10.1016/j.bmc.2007.06.048

Gorbe, A., Giricz, Z., Szunyog, A., Baxter, Gary Francis

, Csont, T. and Ferdinandy, P. 2008. Role of NO-cGMP-PKG signalling in the protection of cardiac myocytes subjected to hypoxia/reoxygenation [Abstract]. Journal of Molecular and Cellular Cardiology 44 (4) , p. 808. 10.1016/j.yjmcc.2008.02.232

Gruden, M., Sewell, Robert David Edmund, Sherstnev, V. and Morozova-Roche, L. 2008. Correlation between protein misfolding, immunity and neurodegeneration [Abstract]. FEBS Journal 275 (S1) , p. 190. 10.1111/j.1742-4658.2008.06448.x

Habashy, H. O., Powe, D. G., Rakha, E. A., Ball, G., Paish, C., Gee, Julia Margaret Wendy

, Nicholson, Robert Ian and Ellis, I. O. 2008. Forkhead-box A1 (FOXA1) expression in breast cancer and its prognostic significance. European Journal of Cancer 44 (11) , pp. 1541-1551. 10.1016/j.ejca.2008.04.020

Hajjaj, F. M., Basra, M., Salek, Sam and Finlay, Andrew Yule

2008. Clinical decision-making in dermatology: the role of clinical and non clinical factors [abstract]. Journal Of Investigative Dermatology 128 (10) , 2550 -2550. 10.1038/jid.2008.267

Hajjaj, F. M., Basra, M., Salek, Sam and Finlay, Andrew Yule

2008. Influences on clinical decision-making in dermatology outpatient clinics [Abstract]. British Journal of Dermatology 159 (S1) , pp. 49-50. 10.1111/j.1365-2133.2008.08538.x

Hamid, Shabaz A., Davidson, S. M., Burley, Dwaine Simon, Yellon, D. M. and Baxter, Gary Francis

2008. Rho-kinase mediates reoxygenation-induced cardiomyocyte death and promotes mitochondrial transition pore opening. Journal of Molecular and Cellular Cardiology 44 (4) , pp. 791-792.

Hardwicke, Joseph, Ferguson, Elaine Lesley

, Moseley, Ryan

, Stephens, Philip

, Thomas, David William

and Duncan, Ruth 2008. Dextrin-rhEGF conjugates as bioresponsive nanomedicines for wound repair. Journal of Controlled Release 130 (3) , pp. 275-283. 10.1016/j.jconrel.2008.07.023

Hayes, Anthony Joseph, Tudor, Debbie, Nowell, Mari Ann, Caterson, Bruce

and Hughes, Clare Elizabeth

2008. Chondroitin sulfate sulfation motifs as putative biomarkers for isolation of articular cartilage progenitor cells. Journal of Histochemistry & Cytochemistry 56 (2) , pp. 125-38. 10.1369/jhc.7A7320.2007

Heard, Charles Martin

and Screen, C. 2008. Probing the permeation enhancement of mefenamic acid by ethanol across full-thickness skin, heat-separated epidermal membrane and heat-separated dermal membrane. International Journal of Pharmaceutics 349 (1-2) , pp. 323-325. 10.1016/j.ijpharm.2007.08.006

Herbert, Amy Angharad, Kidd, Emma Jane

and Broadley, Kenneth John

2008. Dietary trace amine-dependent vasoconstriction in porcine coronary artery. British Journal of Pharmacology 155 (4) , pp. 525-534. 10.1038/bjp.2008.286

Hiscox, Stephen Edward

, Goddard, Lindy, Jordan, Nicola Jane, Smith, Chris, Harper, Maureen Elaine, Nicholson, Robert Ian and Gee, Julia Margaret Wendy

2008. Overexpression of CD44 in acquired tamoxifen-resistant breast cancer cells augments their migratory response to heregulin beta 1 [Abstract]. Breast Cancer Research 10 (S2) , P34. 10.1186/bcr1918

Hiscox, Stephen Edward

and Nicholson, Robert Ian 2008. Src inhibitors in breast cancer therapy. Expert Opinion on Therapeutic Targets 12 (6) , pp. 757-767. 10.1517/14728220802133204

Huber, Kelly, Patel, Poulam, Zhang, Lei, Evans, Helen, Westwell, Andrew D.

, Fischer, Peter M., Chan, Stephen and Martin, Stewart 2008. 2- [(1-methylpropyl)dithio] -1H-imidazole inhibits tubulin polymerization through cysteine oxidation. Molecular Cancer Therapeutics 7 (1) , pp. 143-151. 10.1158/1535-7163.mct-07-0486

Hunter, Laura J., Newcombe, Robert

, Richmond, Stephen

, Owens, J. and Addy, Liam D. 2008. The Cardiff Dental Survey: oral hygiene, gingival and periodontal health in relation to smoking in young adults. International Journal of Dental Hygiene 6 (3) , pp. 199-204. 10.1111/j.1601-5037.2008.00311.x

Hurtado, A., Holmes, K. A., Geistlinger, T. R., Hutcheson, Iain Robert, Nicholson, Robert Ian, Brown, M., Jiang, J., Howat, W. J., Ali, S. and Carroll, J. S. 2008. Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen. Nature 456 (7222) , pp. 663-666. 10.1038/nature07483

Hurtado, Antoni, Holmes, Kelly A., Geistlinger, Timothy R., Hutcheson, Iain Robert, Nicholson, Robert Ian, Brown, Myles, Jiang, Jie, Howat, William J., Ali, Simak and Carroll, Jason S. 2008. Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen [Letter]. Nature 456 (7222) , pp. 663-666. 10.1038/nature07483

James, Delyth H. and French, D. P. 2008. The development of the Self-Medicating Scale (SMS): a scale to measure people's beliefs about self-medication. Pharmacy World & Science 30 (6) , pp. 794-800. 10.1007/s11096-008-9227-2

James, K. Lynette, Barlow, Dave, Burfield, Robin, Hiom, Sarah, Roberts, Dave and Whittlesea, Cate 2008. A study of unprevented dispensing incidents in Welsh NHS hospitals. International Journal of Pharmacy Practice 16 (3) , pp. 175-188. 10.1211/ijpp.16.3.0008

James, K. Lynette, Barlow, David, Hiom, Sarah, Roberts, Dave and Whittlesea, Cate 2008. Development and use of the critical incident technique in evaluating causes of dispensing incidents. International Journal of Pharmacy Practice 16 (4) , pp. 239-249. 10.1211/ijpp.16.4.0006

James, Delyth H., Hatten, Sarah Elizabeth, Roberts, Debra and John, David Neale

2008. Identifying criteria for assessing the quality of medicines use review referral documentation by community pharmacists. International Journal of Pharmacy Practice 16 (6) , pp. 365-374. 10.1211/ijpp.16.6.0005

Jasamai, Malina, Balzarini, Jan and Simons, Claire

2008. 6-Azathymidine-4′-thionucleosides: synthesis and antiviral evaluation. Journal of Enzyme Inhibition and Medicinal Chemistry 23 (1) , pp. 56-61. 10.1080/14756360701442340

Jin, J., Pastrello, D., Penning, N. A. and Jones, Arwyn Tomos

2008. Clustering of endocytic organelles in parental and drug-resistant myeloid leukaemia cell lines lacking centrosomally organised microtubule arrays. The International Journal of Biochemistry & Cell Biology 40 (10) , pp. 2240-2252. 10.1016/j.bioce1.2008.03.004

Jones, Sarah L., Parry, Sharon Maree, O'Brien, Sarah J. and Palmer, Stephen Royston 2008. Operational practices associated with foodborne disease outbreaks in the catering industry in England and Wales. Journal of Food Protection 71 (8) , pp. 1659-1665.

Jones, Arwyn Tomos

2008. Gateways and tools for drug delivery: Endocytic pathways and the cellular dynamics of cell penetrating peptides. International Journal of Pharmaceutics 354 (1-2) , pp. 34-38. 10.1016/j.ijpharm.2007.10.046

Kadri, Hachemi, Dale, Trevor Clive

, Ewan, Kenneth Burnside Ramsay

and Westwell, Andrew

2008. The design, synthesis and antitumour evaluation of novel small molecule inhibitors of the Dishevelled PDZ domain [Poster Presentation/Abstract]. EJC Supplements 6 (12) , p. 137. 10.1016/S1359-6349(08)72370-X

Kadri, Hachemi, Matthews, C. S., Bradshaw, T. D., Stevens, M. F. G. and Westwell, Andrew

2008. Synthesis and antitumour evaluation of novel 2-phenylbenzimidazoles. Journal of Enzyme Inhibition and Medicinal Chemistry 23 (5) , pp. 641-647. 10.1080/14756360802205398

Kang, T. J., Basu, S., Zhang, L., Thomas, K. E., Vogel, S. N., Baillie, Les

and Cross, A. S. 2008. Bacillus anthracis spores and lethal toxin induce IL-1 beta via functionally distinct signaling pathways. European Journal of Immunology 38 (6) , pp. 1574-1584. 10.1002/eji.200838141

Kleinz, Matthias J. and Baxter, Gary Francis

2008. Apelin reduces myocardial reperfusion injury independently of PI3K/Akt and P70S6 kinase. Regulatory Peptides 146 (1-3) , pp. 271-277. 10.1016/j.regpep.2007.10.002

Knowlden, Janice Mary, Jones, Helen E., Barrow, Denise, Gee, Julia Margaret Wendy

, Nicholson, Robert Ian and Hutcheson, Iain Robert 2008. Insulin receptor substrate-1 involvement in epidermal growth factor receptor and insulin-like growth factor receptor signalling: implication for Gefitinib ('Iressa') response and resistance. Breast Cancer Research and Treatment 111 (1) , pp. 79-91. 10.1007/s10549-007-9763-9

Kosuge, Michie., Takeuchi, Toshihide, Nakase, Ikuhiko, Jones, Arwyn

and Futaki, Shiroh 2008. Cellular internalization and distribution of arginine-rich peptides as a function of extracellular peptide concentration, serum, and plasma membrane associated proteoglycans. Bioconjugate Chemistry 19 (3) , pp. 656-664. 10.1021/bc700289w

Laimou, D., Mantzourani, Efthymia D.

, Platts, James Alexis

, Matsoukas, M. T., Troganis, A. and Tselios, T. 2008. Molecular modeling of GnRH analogues in DMSO solution using nuclear magnetic resonance (NMR) and molecular dynamics (MD) [Abstract]. Journal of Peptide Science 14 (S1) , pp. 128-129. 10.1002/psc.1090

Lane, Emma Louise

, Cheetham, S. and Jenner, P. 2008. Striatal output markers do not alter in response to circling behaviour in 6-OHDA lesioned rats produced by acute or chronic administration of the monoamine uptake inhibitor BTS 74 398. Journal of Neural Transmission 115 (3) , pp. 423-429. 10.1007/s00702-007-0854-x

Lane, Emma Louise

and Dunnett, Stephen Bruce

2008. Animal models of Parkinson's disease and L-dopa induced dyskinesia: How close are we to the clinic? Psychopharmacology 199 (3) , pp. 303-312. 10.1007/s00213-007-0931-8

Lane, Emma Louise

, Soulet, D., Vercammen, L., Cenci, M. A. and Brundin, P. 2008. Neuroinflammation in the generation of post-transplantation dyskinesia in Parkinson's disease. Neurobiology of Disease 32 (2) , pp. 220-228. 10.1016/j.nbd.2008.06.011

Lau, Wing Man

, White, Alex William

, Gallagher, S. J., Donaldson, M., McNaughton, G. and Heard, Charles Martin

2008. Scope and limitations of the co-drug approach to topical drug delivery. Current Pharmaceutical Design 14 (8) , pp. 794-802.

Law, Jennifer H., Habibi, Golareh, Hu, Kaiji, Masoudi, Hamid, Wang, Michelle. Y. C., Stratford, Anna L., Park, Eugene, Gee, Julia Margaret Wendy

, Finlay, Pauline, Jones, Helen E., Nicholson, Robert Ian, Carboni, Joan, Gottardis, Marco, Pollak, Michael and Dunn, Sandra E. 2008. Phosphorylated insulin-like growth factor-I/insulin receptor is present in all breast cancer subtypes and is related to poor survival. Cancer Research 68 (24) , pp. 10238-10246. 10.1158/0008-5472.CAN-08-2755

Lisco, Andrea, Vanpouille, Christophe, Tchesnokov, Egor P., Grivel, Jean Charles, Biancotto, Angélique, Brichacek, Beda, Elliott, Julie, Fromentin, Emilie, Shattock, Robert, Anton, Peter, Gorelick, Robert, Balzarini, Jan, McGuigan, Christopher

, Derudas, Marco, Gotte, Matthias, Schinazi, Raymond F. and Margolis, Leonid. 2008. Acyclovir is activated into a HIV-1 reverse transcriptase inhibitor in herpesvirus-infected human tissues. Cell Host & Microbe 4 (3) , pp. 260-270. 10.1016/j.chom.2008.07.008

Maillard, Jean-Yves

and Cheeseman, Keely Emma 2008. Response to: Price EH, Ayliffe G, 'Hot hospitals and what happened to wash, rinse and dry? Recent changes to cleaning, disinfection and environmental ventilation'. Journal of Hospital Infection 70 (4) , pp. 376-378.

Mantzourani, Efthymia D.

, Blokar, Klemen, Tselios, Theodore V., Matsoukas, John M., Platts, James A., Mavromoustakos, Thomas M. and Grdadolnik, Simona Golic 2008. A combined NMR and molecular dynamics simulation study to determine the conformational properties of agonists and antagonists against experimental autoimmune encephalomyelitis. Bioorganic & Medicinal Chemistry 16 (5) , pp. 2171-2182. 10.1016/j.bmc.2007.11.083

Mantzourani, Efthymia D.

, Laimou, Despina, Matsoukas, Minos T. and Tselios, Theodore 2008. Peptides as therapeutic agents or drug leads for autoimmune, hormone dependent and cardiovascular diseases. Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry (Formerly Cu rrent Medicinal Chemistry - Anti-Inflammatory and Anti-Allergy Agents) 7 (4) , pp. 294-306. 10.2174/187152308786847799

Martin, D. J. H., Denyer, S. P., McDonnell, G. and Maillard, J.-Y.

2008. Resistance and cross-resistance to oxidising agents of bacterial isolates from endoscope washer disinfectors. Journal of Hospital Infection 69 (4) , pp. 377-383. 10.1016/j.jhin.2008.04.010

Matthews, Stephanie Beatrix, Rowlands, W. P., Chang, D. and Campbell, Anthony Keith 2008. Development of educational material for families with FH [Abstract]. Atherosclerosis 199 (1) , p. 234. 10.1016/j.atherosclerosis.2008.04.033

McGuigan, Christopher

, Derudas, Marco, Bugert, Joachim Jakob

, Andrei, G., Snoeck, R. and Balzarini, J. 2008. Successful kinase bypass with new acyclovir phosphoramidate prodrugs. Biorganic and Medicinal Chemistry Letters 18 (15) , pp. 4364-4367. 10.1016/j.bmcl.2008.06.069

McGuigan, Christopher

, Migliore, Marco, Henson, G., Patti, J., Andrei, G., Snoeck, R. and Balzarini, J. 2008. Design, synthesis and evaluation of novel Anti-VZV BCNAs. Antiviral Research 78 (2) , 29. 10.1016/j.antiviral.2008.01.047

McGuigan, Christopher

, Serpi, Michaela

, Bibbo, Rita, Roberts, Helen Christina, Hughes, Clare Elizabeth

, Caterson, Bruce

, Gibert, Ana Torrent and Verson, Carlos Raul Alaez 2008. Phosphate prodrugs derived from N-acetylglucosamine have enhanced chondroprotective activity in explant cultures and represent a new lead in antiosteoarthritis drug discovery. Journal of Medicinal Chemistry 51 (18) , pp. 5807-5812. 10.1021/jm800594c

Morgan, Liam David

, Nicholson, Robert and Hiscox, Stephen

2008. Src as a therapeutic target in breast cancer. Endocrine‚ Metabolic & Immune Disorders - Drug Targets 8 (4) , pp. 273-278. 10.2174/187153008786848295

Morris, Andrew

, Brain, Keith Roger and Heard, Charles Martin

2008. Synthesis of haloperidol prodrugs and their hydrolysis by porcine liver esterase. Drug Metabolism Letters 2 (4) , pp. 275-279. 10.2174/187231208786734111

Naseem, Riffat, Holland, I. Barry, Jacq, Annick, Wann, Kenneth Taylor and Campbell, Anthony Keith 2008. pH and monovalent cations regulate cytosolic free Ca2+ in E. coli. BBA - Biochimica et Biophysica Acta 1778 (6) , pp. 1415-1422. 10.1016/j.bbamem.2008.02.006

Nash, Deborah, Lane, E., Herath, S. and Sheldon, I. M. 2008. Endometrial explant culture for characterizing equine endometritis. American Journal Of Reproductive Immunology 59 (2) , pp. 105-117. 10.1111/j.1600-0897.2007.00548.x

Occhipinti, Paola and Griffiths, Peter Charles 2008. Quantifying diffusion in mucosal systems by pulsed-gradient spin-echo NMR. Advanced Drug Delivery Reviews 60 (15) , pp. 1570-1582. 10.1016/j.addr.2008.08.006

Omidi, Y., Barar, J., Ahmadian, S., Heidari, H. R. and Gumbleton, Mark

2008. Characterization and astrocytic modulation of system L transporters in brain microvasculature endothelial cells. Cell Biochemistry and Function 26 (3) , pp. 381-391. 10.1002/cbf.1455

Osmani, Q., Hughes, H., Flavin, K., Hedin-Dahlstrom, Jimmy, Allender, Christopher John, Frisby, J. and McLoughlin, P. 2008. The use of FTIR and NMR spectroscopies to study prepolymerisation interactions in nitrogen heterocycles. Analytical and Bioanalytical Chemistry 391 (4) , pp. 1229-1236. 10.1007/s00216-008-1867-5

Parmeggiani, F

, Pellarin, R, Larsen, A, Varadamsetty, G, Stumpp, M, Zerbe, O, Caflisch, A and Plueckthun, A 2008. Designed armadillo repeat proteins as general peptide-binding scaffolds: Consensus design and computational optimization of the hydrophobic core. Journal of Molecular Biology 376 (5) , pp. 1282-1304. 10.1016/j.jmb.2007.12.014

Pearton, Marc, Allender, Christopher John, Brain, Keith Roger, Anstey, Alexander Vincent

, Gateley, Chris, Wilke, Nicolle, Morrissey, Anthony and Birchall, James Caradoc

2008. Gene delivery to the epidermal cells of human skin explants using microfabricated microneedles and hydrogel formulations. Pharmaceutical Research 25 (2) , pp. 407-416. 10.1007/s11095-007-9360-y

Penson, Peter Edward, Ford, William Richard

, Kidd, Emma Jane

and Broadley, Kenneth John

2008. Activation of beta-adrenoceptors mimics preconditioning of rat-isolated atria and ventricles against ischaemic contractile dysfunction. Naunyn-Schmiedeberg's Archives of Pharmacology 378 (6) , pp. 589-597. 10.1007/s00210-008-0331-6

Penson, Peter Edward, Ford, William Richard

, Kidd, Emma Jane

and Broadley, Kenneth John

2008. Protective role of beta 2- and beta 3-adrenoceptors at reperfusion in isolated rat heart. Journal of Molecular and Cellular Cardiology 44 (4) , p. 719. 10.1016/j.yjmcc.2008.02.020

Rakha, E. A., El-Sayed, M. E., Powe, D. G., Green, A. R., Habashy, H., Grainge, M. J., Robertson, J. F. R., Blamey, R., Gee, Julia Margaret Wendy

, Nicholson, Robert Ian, Lee, A. H. S. and Ellis, I. O. 2008. Invasive lobular carcinoma of the breast: Response to hormonal therapy and outcomes. European Journal of Cancer 44 (1) , pp. 73-83. 10.1016/j.ejca.2007.10.009

Richardson, Simon C. W., Wallom, Kerri-Lee, Ferguson, Elaine Lesley

, Deacon, Simon P. E., Davies, Matthew W., Powell, Alison J., Piper, Robert C. and Duncan, Ruth 2008. The use of fluorescence microscopy to define polymer localisation to the late endocytic compartments in cells that are targets for drug delivery. Journal of Controlled Release 127 (1) , pp. 1-11. 10.1016/j.jconrel.2007.12.015

Romagnoli, R., Baraldi, P. G., Carrion, M. D., Cara, C. L., Cruz-Lopez, O., Preti, D., Tolomeo, M., Grimaudo, S., Di Cristina, A., Zonta, Nicola, Balzarini, J., Brancale, Andrea

, Sarkar, T. and Hamel, E. 2008. Design, synthesis, and biological evaluation of thiophene analogues of chalcones. Bioorganic & Medicinal Chemistry 16 (10) , pp. 5367-5376. 10.1016/j.bmc.2008.04.026

Romagnoli, R., Baraldi, P. G., Carrion, M. D., Cruz-Lopez, O., Cara, C. L., Tolomeo, M., Grimaudo, S., Di Cristina, A., Pipitone, M. R., Balzarini, J., Kandil, Sahar

, Brancale, Andrea

, Sarkar, T. and Hamel, E. 2008. Synthesis and biological evaluation of 2-amino-3-(3 ',4 ',5 '-trimethoxybenzoyl)-6-substituted-4,5,6,7-tetrahydrothieno 2,3-c pyridi ne derivatives as antimitotic agents and inhibitors of tubulin polymerization. Bioorganic & Medicinal Chemistry Letters 18 (18) , pp. 5041-5045. 10.1016/j.bmcl.2008.08.006

Romagnoli, R., Baraldi, P. G., Sarkar, T., Carrion, M. D., Cara, C. L., Cruz-Lopez, O., Preti, D., Tabrizi, M. A., Tolomeo, M., Grimaudo, S., Di Cristina, A., Zonta, Nicola, Balzarini, J., Brancale, Andrea

, Hsieh, H. P. and Hamel, E. 2008. Synthesis and biological evaluation of 1-methyl-2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors. Journal of Medicinal Chemistry 51 (5) , pp. 1464-1468. 10.1021/jm7011547

Romagnoli, R., Baraldi, P. G., Sarkar, T., Carrion, M. D., Cruz-Lopez, O., Cara, C. L., Tolomeo, M., Grimaudo, S., Di Cristina, A., Pipitone, M. R., Balzarini, J., Gambari, R., Ilaria, L., Saletti, R., Brancale, Andrea

and Hamel, E. 2008. Synthesis and biological evaluation of 2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-N, N-dimethylamino benzo b furan derivatives as inhibitors of tubulin polymerization. Bioorganic & Medicinal Chemistry 16 (18) , pp. 8419-8426. 10.1016/j.bmc.2008.08.029

Routledge, Philip Alexander 2008. Antidotes for European viper envenomation [Abstract]. Clinical Toxicology 46 (5) , p. 401. 10.1080/15563650802071703

Routledge, Philip Alexander 2008. The European herbal medicines directive: could it have saved the lives of Romeo and Juliet? Drug Safety 31 (5) , pp. 416-418. 10.2165/00002018-200831050-00006

Salek, Sam, Gill, N., Gates, B., Rice, L. and Weeks, D. 2008. Evaluation of the effectiveness of sliding scale insulin for glycemic control in the home care setting [Abstract]. Pharmacy World & Science 30 (5) , p. 709. 10.1007/s11096-008-9226-3

Salek, Sam, Lewis-Smith, R. E., Ives, T. J. and Rake, K. M. 2008. How prevalent are opioid misuse and affective disorders in patients with fibromyalgia? Pharmacy World and Science 30 (5) , pp. 719-720.

Salek, Sam, Mallia-Milanes, A., McAuslane, N. and Walker, Stuart 2008. Can systematic use of scorecards be of value in the evaluation of the quality of industry submissions and their regulatory review? [Abstract]. Pharmacy World and Science 30 (5) , p. 721. 10.1007/s11096-008-9226-3

Salek, Sam, Morgan, L., McAuslane, N., Read, K. and Walker, Stuart 2008. Companies submission strategies and regulatory approval times greatly influence patient access to medicine [Abstract]. Pharmacy World and Science 30 (5) , p. 720. 10.1007/s11096-008-9226-3

Salek, Sam, Patel, J. and Schwartz, C. 2008. Evaluation of a rapid streptococcus testing service in the community pharmacy. Pharmacy World and Science 30 (5) , pp. 707-708.

Shrewsbury, Stephen B., Cook, Robert O., Taylor, Glyn, Edwards, Ceri and Ramadan, Nabih M. 2008. Safety and pharmacokinetics of dihydroergotamine mesylate administered via a novel (Tempo™) inhaler. Headache 48 (3) , pp. 355-367.

Slusarczyk, Magdalena

, De Borggraeve, Wim M., Hoornaert, Georges, Deroose, Frederik and Linders, Joannes T. M. 2008. Synthesis and biological evaluation of methylene-bridged analogs of the potent cannabinoid receptor antagonist rimonabant. European Journal of Organic Chemistry 2008 (8) , pp. 1350-1357. 10.1002/ejoc.200700960

Smith, N. and Broadley, Kenneth John

2008. Adenosine receptor subtypes in the airways responses to 5 '-adenosine monophosphate inhalation of sensitized guinea-pigs. Clinical and Experimental Allergy 38 (9) , pp. 1536-1547. 10.1111/j.1365-2222.2008.03034.x

Stone, A., Jones, H., Giles, M., Gee, Julia Margaret Wendy

and Nicholson, Robert Ian 2008. Anti-oestrogen therapy switches off tumour suppressors and proapoptotic genes in breast cancer and reveals a new therapeutic opportunity [Abstract]. Breast Cancer Research 10 (s2) , P41. 10.1186/bcr1925

Taylor, Kathryn Mary

2008. A distinct role in breast cancer for two LIV-1 family zinc transporters. Biochemical Society Transactions 36 (6) , pp. 1247-1251. 10.1042/bst0361247

Taylor, Kathryn Mary

, Jordan, Nicola JAne, Hiscox, Stephen Edward

, Gee, Julia Margaret Wendy

and Nicholson, Robert Ian 2008. Zinc transporter HKE4 as a new target in antihormone resistance of breast cancer [Abstract]. Breast Cancer Research 10 (s2) , P42. 10.1186/bcr1926

Taylor, Kathryn Mary

, Vichova, Petra, Jordan, Nicola Jane, Hiscox, Stephen Edward

, Hendley, Rhiannon and Nicholson, Robert Ian 2008. ZIP7-mediated intracellular zinc transport contributes to aberrant growth factor signaling in antihormone-resistant breast cancer cells. Endocrinology 149 (10) , pp. 4912-4920. 10.1210/en.2008-0351

Thompson, A., Brennan, K., Cox, A., Gee, Julia Margaret Wendy

, Harcourt, D., Harris, A., Harvie, M., Holen, I., Howell, A., Nicholson, Robert Ian, Steel, M. and Streuli, C. 2008. Evaluation of the current knowledge limitations in breast cancer research: a gap analysis. Breast Cancer Research 10 (2) , R26. 10.1186/bcr1983

Urasov, V., Gruden, M., Storogeva, Z., Sewell, Robert David Edmund and Sherstnev, V. 2008. Linked mechanisms of neurogliogenesis and apoptosis in adult rat brain. Febs Journal 275 , pp. 298-299.

Waud, Jonathan P., Matthews, Stephanie Beatrix and Campbell, Anthony Keith 2008. Measurement of breath hydrogen and methane, together with lactase genotype, defines the current best practice for investigation of lactose sensitivity. Annals of Clinical Biochemistry 45 (1) , pp. 50-58. 10.1258/acb.2007.007147

Westwell, Andrew

2008. Advances in Cancer Drug Discovery - A British Association for Cancer Research Meeting. IDrugs 11 (11) , pp. 783-786.

White, Alex William

, Westwell, Andrew

and Brahemi, Ghali 2008. Protein-protein interactions as targets for small-molecule therapeutics in cancer. Expert Reviews in Molecular Medicine 10 (e8) , pp. 1-14. 10.1017/S1462399408000641

Ylänne, Virpi

and John, David Neale

2008. Roles of medicines counter assistants in advice giving in community pharmacies: a Discourse Analysis. Pharmacy World and Science 30 (2) , pp. 199-207. 10.1007/s11096-007-9165-4

Yoo, C. B., Valente, R., Congiatu, C., Gavazza, F., Angell, A., Siddiqui, M. A., Jones, P. A., McGuigan, Christopher

and Marquez, V. E. 2008. Activation of p16 Gene Silenced by DNA Methylation in Cancer Cells by Phosphoramidate Derivatives of 2 '-Deoxyzebularine. Journal of Medicinal Chemistry 51 (23) , pp. 7593-7601. 10.1021/jm8005965

Zahari, N. M., Taylor, Kathryn Mary

and Nicholson, Robert Ian 2008. Functional evaluation of members of the LIV-1 family of proteins and their role in breast cancer. EJC Supplements 6 (12) , p. 184.

Ziedan, Noha, Westwell, Andrew

and Fogli, S. 2008. Design and synthesis of novel indole derivatives as selective apoptosis-inducers. EJC Supplements 6 (12) , pp. 45-46.

Zietlow, Rike, Lane, Emma Louise

, Dunnett, Stephen Bruce

and Rosser, Anne Elizabeth

2008. Human stem cells for CNS repair. Cell and Tissue Research 331 (1) , pp. 301-322. 10.1007/s00441-007-0488-1

Book

Hughes, Mary Louise

, John, David Neale

and Jones, Arwyn Tomos

2008. The role of the Welsh language in community pharmacy service provision in Wales. London: Pharmacy Practice Research Trust.

Book Section

Hutcheson, Iain Robert, Gee, Julia Margaret Wendy

and Nicholson, Robert Ian 2008. MAP Kinase family members and endocrine response and survival in breast cancer. Walker, Rosemary A. and Thompson, Alastair M., eds. Prognostic and predictive factors in breast cancer. 2nd ed., London: Informa Healthcare, pp. 122-138.

Lane, Emma Louise

, Carlsson, Thomas, Kirik, Deniz and Dunnett, Stephen Bruce

2008. Animal models of Parkinson's Disease. Conn, P. Michael, ed. 2008 Sourcebook of Models for Biomedical Research, Humana Press, pp. 313-322. (10.1007/978-1-59745-285-4_34)

Nicholson, Robert Ian, Hutcheson, Iain Robert, Jones, Helen Elizabeth, Taylor, Kathryn Mary

, Hiscox, Stephen Edward

and Gee, Julia Margaret Wendy

2008. Compensatory signalling induced by anti-hormone and anti-growth factor therapies in breast cancer: a starting point for the development of resistance to targeted therapies. Pasqualini, Jorge R., ed. Breast cancer: prognosis, treatment and prevention. 2nd ed, London: Informa Healthcare, pp. 123-136.

Conference or Workshop Item

Aboraia, A. S. M., Gomaa, M. S. and Simons, Claire

2008. Molecular modelling and synthesis of novel CYP26A1 inhibitors [334 Poster]. Presented at: EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Geneva, Switzerland, 20-24 October 2008. 20th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics :. EJC Supplements (6) Amsterdam; London: Elsevier, p. 106. 10.1016/S1359-6349(08)72268-7

Thesis

Aderounmu, Adetomilola Olusegun 2008. Development and validation of a new instrument to measure the socioeconomic impact of medication-related problems in community pharmacy setting. PhD Thesis, Cardiff University.

Alqallaf, Sayed Mahmood 2008. Characterisation of P2X7 receptors in human osteoblasts and modulation by oestrogen. PhD Thesis, Cardiff University.

Castell, Oliver Kieran

2008. Microfluidic devices for continuous liquid-liquid-solid chemical extractions. PhD Thesis, Cardiff University.

Cunningham, Clare. 2008. Development of an electronic treatment decision aid for Parkinson's disease using mutli-criteria decision analysis. PhD Thesis, Cardiff University.

Davison, Zoe. 2008. Transcutaneous delivery of anti-breast cancer agents. PhD Thesis, Cardiff University.

Dhippayom, Teerapon. 2008. Drug utilisation studies on the impact of the reduction of the prescription charge in Wales and the reclassification of medicines. PhD Thesis, Cardiff University.

Dieudonne, Lucile 2008. Synthesis, characterisation and cytotoxicity evaluation of novel polymeric carriers for polymer therapeutics: From free radical polymerisation to atom transfer radical polymerisation. PhD Thesis, Cardiff University.

Fehler, Martina 2008. Investigation of trace amine receptors in the cardiovascular systems. PhD Thesis, Cardiff University.

Ferguson, Elaine Lesley

2008. Bioresponsive polymer-phospholipase A2 conjugates as novel anti-cancer agents. PhD Thesis, Cardiff University.

Gomaa, Mohamed Sayed 2008. Design and synthesis of some CUP26 and CYP24 inhibitors as indirect differentiating agents for prostate and breast cancer. PhD Thesis, Cardiff University.

Henney, Neil C. 2008. Expression and characteristics of ion channels in osteoblasts : putative roles for TRP and K+ channels. PhD Thesis, Cardiff University.

Knowlden, Janice M. 2008. Role of insulin-like growth factor-type 1 receptor (IGF-IR) signalling in tamoxifen-resistant breast cancer. PhD Thesis, Cardiff University.

Pautus, Stephane Mathieu 2008. Design, synthesis and binding studies of novel CYP26 inhibitors. PhD Thesis, Cardiff University.

Stone, Andrew 2008. Identification of genes associated with the maintenance of the tamoxifen resistant breast cancer cell phenotype following tamoxifen withdrawal. PhD Thesis, Cardiff University.

Wallom, Kerri-Lee. 2008. Synthesis and biological characterisation of HPMA copolymer-mannose conjugates designed for intracellular delivery of anti-leishmanial compounds to macrophages. PhD Thesis, Cardiff University.

Williams, Sophie Elizabeth 2008. Nanoscale surface patterning as a means of controlling protein immobilisation. PhD Thesis, Cardiff University.

Zahari, Normawati Mohamad 2008. Functional evaluation of members of the LIV-1 family of proteins and their role in breast cancer. PhD Thesis, Cardiff University.

This list was generated on Mon Feb 10 11:01:46 2025 GMT.