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Number of items: 152.

Abdelouahab, Nassima and Heard, Charles Martin

2010. Estimation of the Relative Antiinflammatory Efficacies of Six Commercial Preparations of Harpagophytum procumbens (Devil's Claw). Phytotherapy Research 24 (3) , pp. 333-338. 10.1002/ptr.2930

Aboraia, Ahmed S., Makowski, Bart, Bahja, Alba, Prosser, David, Brancale, Andrea

, Jones, Glenville and Simons, Claire

2010. Synthesis and CYP24A1 inhibitory activity of (E)-2-(2-substituted benzylidene)- and 2-(2-substituted benzyl)-6-methoxy-tetralones. European Journal of Medicinal Chemistry 45 (10) , pp. 4427-4434. 10.1016/j.ejmech.2010.07.001

Aboraia, Ahmed S., Yee, Sook Wah, Gomaa, Mohamed Sayed, Shah, Nikhil, Robotham, Anna C., Makowski, Bart, Prosser, David, Brancale, Andrea

, Jones, Glenville and Simons, Claire

2010. Synthesis and CYP24A1 inhibitory activity of N-(2-(1H-imidazol-1-yl)-2-phenylethyl)arylamides. Bioorganic & Medicinal Chemistry 18 (14) , pp. 4939-4946. 10.1016/j.bmc.2010.06.011

Agrawal, A., Robertson, J. F. R., Gutteridge, E., Cheung, K. L., Ellis, I. O., Nicholson, Robert Ian and Gee, Julia Margaret Wendy

2010. 182 Long-term effect of fulvestrant on hormone receptors and proliferation marker in breast cancer [Abstract]. EJC Supplements 8 (3) , p. 111. 10.1016/S1359-6349(10)70213-5

Al Moubarak, Ehab Moustapha and Simons, Claire

2010. A homology model for Clostridium difficile methionyl tRNA synthetase: active site analysis and docking interactions. Journal of Molecular Modeling 17 (7) , pp. 1679-1693. 10.1007/s00894-010-0871-9

Al-Motarreb, Ahmed, Al-Habori, M. and Broadley, Kenneth John

2010. Khat chewing, cardiovascular diseases and other internal medical problems: the current situation and directions for future research. Journal of Ethnopharmacology 132 (3) , pp. 540-548. 10.1016/j.jep.2010.07.001

Al-Soraj, Monerah H., Watkins, Catherine Louise, Vercauteren, Dries, De Smedt, Stefaan, Braeckmans, Kevin and Jones, Arwyn Tomos

2010. siRNA versus pharmacological inhibition of endocytic pathways for studying cellular uptake of cell penetrating peptides and other drug delivery vectors. Drug Discovery Today 15 (23-24) , p. 1103. 10.1016/j.drudis.2010.09.411

Aljayyoussi, Ghaith, Ford, William Richard

, McKeown, Neil B. and Gumbleton, Mark

2010. Differential transport of anionic PAMAM dendrimers across in vitro biological barriers [Abstract]. Drug Discovery Today 15 (23-24) , p. 1114. 10.1016/j.drudis.2010.09.440

Andreou, Dimitra, Hussey, M., Griffiths, Sian Wyn

and Gozlan, R. E. 2010. Influence of host reproductive state on Sphaerothecum destruens prevalence and infection level. Parasitology 138 (1) , pp. 26-34. 10.1017/S0031182010000983

Baillie, Les

, Huwar, Theresa B., Moore, Stephen, Mellado-Sanchez, Gabriela, Rodriguez, Liliana, Neeson, Brendan N., Flick-Smith, Helen C., Jenner, Dominic C., Atkins, Helen S., Ingram, Rebecca J., Altmann, Danny M., Nataro, James P. and Pasetti, Marcela F. 2010. An anthrax subunit vaccine candidate based on protective regions of Bacillus anthracis protective antigen and lethal factor. Vaccine 28 (41) , pp. 6740-6748. 10.1016/j.vaccine.2010.07.075

Bains, Baljinder Kaur 2010. Novel pDNA particles for pulmonary administration. PhD Thesis, Cardiff University.

Bains, Baljinder Kaur, Birchall, James Caradoc

, Toon, Richard and Taylor, Glyn 2010. In vitro reporter gene transfection via plasm ID DNA delivered by metered dose inhaler. Journal of Pharmaceutical Sciences 99 (7) , pp. 3089-3099. 10.1002/jps.22085

Ballam, L. and Heard, Charles Martin

2010. Pre-Treatment with Aloe vera Juice Does Not Enhance the in vitro Permeation of Ketoprofen across Skin. Skin Pharmacology and Physiology 23 (2) , pp. 113-116. 10.1159/000265682

Barar, Jaleh, Gumbleton, Mark

, Asadi, M. and Omidi, Y. 2010. Barrier functionality and transport machineries of human ECV304 cells. Medical Science Monitor 16 (1) , BR52-BR60.

Basra, M. K., Williams, Owain, McKnight, Rhiannon and Salek, Mir-saeed 2010. A Preference Based Approach to Assess Quality of Life of Family Members of Patients with Inflammatory Skin Diseases [Abstract]. Journal of Investigative Dermatology 130 (S2) , S71. 10.1038/jid.2010.238

Basra, M. K. A., Camilleri, L., Salek, Mir-saeed and Finlay, Andrew Yule

2010. Strengthening the Dermatology Life Quality Index's clinical meaning: minimal clinically important difference of the scores [Abstract]. British Journal of Dermatology 163 (S1) , p. 41. 10.1111/j.1365-2133.2010.09728.x

Bhatti, Zaheer Uddin, Salek, Mir-saeed and Finlay, Andrew Yule

2010. The influence of chronic skin diseases on major life-changing decisions as a parameter for the assessment of long-term impact [Abstract]. British Journal of Dermatology 163 (S1) , pp. 39-40. 10.1111/j.1365-2133.2010.09728.x

Blamey, R. W., Hornmark-Stenstam, B., Ball, G., Blichert-Toft, M., Cataliotti, L., Fourquet, A., Gee, Julia Margaret Wendy

, Holli, K., Jakesz, R., Kerin, M., Mansel, Robert Edward

, Nicholson, Robert Ian, Pienkowski, T., Pinder, S., Sundquist, M., van de Vijver, M. and Ellis, I. 2010. ONCOPOOL - A European database for 16,944 cases of breast cancer. European Journal of Cancer 46 (1) , pp. 56-71. 10.1016/j.ejca.2009.09.009

Brahemi, Ghali, Burger, A. M., Westwell, Andrew

and Brancale, Andrea

2010. Homology Modelling of Human E1 Ubiquitin Activating Enzyme. Letters in Drug Design & Discovery 7 (1) , pp. 57-62. 10.2174/157018010789869316

Brahemi, Ghali, Kona, Fathima R., Fiasella, Annal, Buac, Daniela, Soukupova, Jitka, Brancale, Andrea

, Burger, Angelika M. and Westwell, Andrew D.

2010. Exploring the structural requirements for inhibition of the ubiquitin E3 ligase breast cancer associated protein 2 (BCA2) as a treatment for breast cancer. Journal of Medicinal Chemistry 53 (7) , pp. 2757-2765. 10.1021/jm901757t

Broadley, Kenneth John

2010. The vascular effects of trace amines and amphetamines. Pharmacology & Therapeutics 125 (3) , pp. 363-375. 10.1016/j.pharmthera.2009.11.005

Broadley, Kenneth John

, Blair, Alan Edward, Kidd, Emma Jane

, Bugert, Joachim Jakob

and Ford, William Richard

2010. Bradykinin-induced lung inflammation and bronchoconstriction: role in parainfluenze-3 virus-induced inflammation and airway hyperreactivity. Journal of Pharmacology and Experimental Therapeutics 335 (3) , pp. 681-692. 10.1124/jpet.110.171876

Broadley, Kenneth John

, Jackson, A. and John, Emma Alison 2010. Comparison of the effects of UTP and 5 '-AMP on guinea-pig lung function and airways mucus secretion [Abstract]. Purinergic Signalling 6 (1) , pp. 140-141. 10.1007/s11302-009-9175-x

Broadley, Kenneth John

, Sykes, Shane C. and Davies, Robin H. 2010. Towards a thermodynamic definition of efficacy in partial agonism: The thermodynamics of efficacy and ligand proton transfer in a G protein-coupled receptor of the rhodopsin class. Biochemical Pharmacology 80 (10) , pp. 1537-1545. 10.1016/j.bcp.2010.07.044

Brooks, Caroline J., Lyons, Ronan A., Jones, Kerina H., Hutton, Andrew J., Walker, Roger, Evans, Karen A., Lloyd, Keith and Ford, David V. 2010. The prescribed duration algorithm: utilising 'free text' from multiple primary care electronic systems. Pharmacoepidemiology and Drug Safety 19 (9) , pp. 983-989. 10.1002/pds.2012

Bruyere, Helene, Westwell, Andrew

and Jones, Arwyn Tomos

2010. Tuning the pH sensitivities of orthoester based compounds for drug delivery applications by simple chemical modification. Bioorganic & Medicinal Chemistry Letters 20 (7) , pp. 2200-2203. 10.1016/j.bmcl.2010.02.035

Campbell, Anthony Keith, Matthews, Stephanie Beatrix, Vassel, Nasrin, Cox, Charles D., Naseem, Riffat, Chaichi, J., Holland, I. B., Green, John Trevor and Wann, Kenneth Taylor 2010. Bacterial metabolic 'toxins': A new mechanism for lactose and food intolerance, and irritable bowel syndrome. Toxicology 278 (3) , pp. 268-276. 10.1016/j.tox.2010.09.001

Cheeseman, Keely 2010. Surveillance of susceptibility profile to antiseptics in ITU isolates of Staphylococcus aureus, including MRSA. PhD Thesis, Cardiff University.

Cheeseman, Keely Emma, Denyer, Stephen Paul, Hosein, I. K., Williams, Gareth John and Maillard, Jean-Yves

2010. Understanding the lethal effect of alcohol hand rubs: an in vitro study with Staphylococcus aureus isolates [Letter]. Journal of Hospital Infection 76 (3) , pp. 264-266. 10.1016/j.jhin.2010.04.020

Chew, Eng-Hui, Nagle, Amrita A., Zhang, Yaochun, Scarmagnani, Silvia, Palaniappan, Puvithira, Bradshaw, Tracey D., Holmgren, Arne and Westwell, Andrew D.

2010. Cinnamaldehydes inhibit thioredoxin reductase and induce Nrf2: potential candidates for cancer therapy and chemoprevention. Free Radical Biology & Medicine 48 (1) , pp. 98-111. 10.1016/j.freeradbiomed.2009.10.028

Cohen, David, Alam, Fasihul, Dunstan, Frank David John

, Myles, Susan, Hughes, Dyfrig A. and Routledge, Philip Alexander 2010. Abolition of prescription co-payments in Wales: an observational study on dispensing rates [Abstract]. Journal of Epidemiology and Community Health 64 , A25-A25. 10.1136/jech.2010.120956.62

Daniels, Stephen, Md Tohid, Siti Farah

, Velanguparackel, Winnie and Westwell, Andrew

2010. The role and future potential of fluorinated biomarkers in positron emission tomography. Expert Opinion on Drug Discovery 5 (3) , pp. 291-304. 10.1517/17460441003652967

Davison, Zoë, Nicholson, Robert I., Denyer, Stephen P. and Heard, Charles M.

2010. A novel diffusion cell model for the in vitro assessment of transcutaneous breast cancer therapeutics: effect of permeants on MCF-7 cells cultured within the receptor compartment. European Journal Of Pharmaceutics and Biopharmaceutics 75 (3) , pp. 411-417. 10.1016/j.ejpb.2010.03.019

Derudas, Marco, Brancale, Andrea

, Naesens, L., Neyts, J., Balzarini, J. and McGuigan, Christopher

2010. Application of the phosphoramidate ProTide approach to the antiviral drug ribavirin. Bioorganic & Medicinal Chemistry 18 (7) , pp. 2748-2755. 10.1016/j.bmc.2010.02.015

Derudas, Marco, Quintiliani, Maurizio, Brancale, Andrea

, Andrei, Graciela, Snoeck, Robert, Balzarini, Jan and McGuigan, Christopher

2010. Evaluation of novel phosphoramidate ProTides of the 2′-fluoro derivatives of a potent anti-varicella zoster virus bicyclic nucleoside analogue. Antiviral Chemistry and Chemotherapy 21 (1) , pp. 15-31. 10.3851/IMP1661

Deslandes, Rhian

, Pandeli, L. and Deslandes, Paul 2010. An evaluation of medication information provision to mental health patients. International Journal of Pharmacy Practice 18 (s1) , p. 16. 10.1111/j.2042-7174.2010.00015.x

Eadala, Praveen, Waud, J. P., Matthews, Stephanie Beatrix, Green, John Trevor and Campbell, Anthony Keith 2010. Lactose in drugs: avoided or allowed to lactose maldigesters? Authors' reply. Alimentary Pharmacology & Therapeutics 31 (8) , pp. 925-926. 10.1111/j.1365-2036.2010.04253.x

Elsey, David, Fowkes, R. C. and Baxter, Gary Francis

2010. Regulation of cardiovascular cell function by hydrogen sulfide (H2S). Cell Biochemistry and Function 28 (2) , pp. 95-106. 10.1002/cbf.1618

Elsey, David, Fowkes, Robert C. and Baxter, Gary Francis

2010. L-cysteine stimulates hydrogen sulfide synthesis in myocardium associated with attenuation of ischemia-reperfusion injury. Journal of Cardiovascular Pharmacology and Therapeutics 15 (1) , pp. 53-59. 10.1177/1074248409357743

Fehler, Martina, Broadley, Kenneth John

, Ford, William Richard

and Kidd, Emma Jane

2010. Identification of trace-amine-associated receptors (TAAR) in the rat aorta and their role in vasoconstriction by beta-phenylethylamine. Naunyn Schmiedeburgs Archives of Pharmacology 382 (4) , pp. 385-398. 10.1007/s00210-010-0554-1

Ferguson, Elaine Lesley

, Richardson, Simon C. W. and Duncan, Ruth 2010. Studies on the mechanism of action of dextrin-phospholipase A2 and its suitability for use in combination therapy. Molecular Pharmaceutics 7 (2) , pp. 510-521. 10.1021/mp900232a

Fernandez-Rodriguez, Sofia, Broadley, Kenneth John

, Ford, William Richard

and Kidd, Emma Jane

2010. Increased muscarinic receptor activity of airway smooth muscle isolated from a mouse model of allergic asthma. Pulmonary Pharmacology and Therapeutics 23 (4) , pp. 300-307. 10.1016/j.pupt.2010.03.001

Finnegan, Michelle, Linley, Ezra, Denyer, Stephen Paul, McDonnell, Gerald, Simons, Claire

and Maillard, Jean-Yves

2010. Mode of action of hydrogen peroxide and other oxidizing agents: differences between liquid and gas forms. Journal of Antimicrobial Chemotherapy 65 (10) , pp. 2108-2115. 10.1093/jac/dkq308

Fricke, Thomas, Mart, Robert J.

, Watkins, Catherine Louise, Jones, Arwyn Tomos

and Allemann, Rudolf Konrad

2010. Click chemistry for the generation of cell permeable apoptotic peptides. Drug Discovery Today 15 (23-24) , p. 1088. 10.1016/j.drudis.2010.09.375

Gorbe, Aniko, Giricz, Zoltan, Szunyog, Andrea, Csont, Tamas, Burley, Dwaine Simon, Baxter, Gary Francis

and Ferdinandy, Peter 2010. Role of cGMP-PKG signaling in the protection of neonatal rat cardiac myocytes subjected to simulated ischemia/reoxygenation. Basic Research in Cardiology 105 (5) , pp. 643-650. 10.1007/s00395-010-0097-0

Griffiths, Peter Charles, Nilmini, Renuka, Carter, Emma

, Dodds, Patrick

, Murphy, Damien Martin

, Khayat, Zeena, Lattanzio, Ettore, Ferruti, Paolo, Heenan, Richard K., King, Stephen M. and Duncan, Ruth 2010. Interaction of an endosomolytic polyamidoamine ISA23 with vesicles mimicking intracellular membranes: A SANS/EPR study. Macromolecular Bioscience 10 (8) , pp. 963-973. 10.1002/mabi.201000040

Griffiths, Peter Charles, Occhipinti, Paolo, Morris, Christopher John, Heenan, Richard K., King, Stephen Michael and Gumbleton, Mark

2010. PGSE-NMR and SANS studies of the interaction of model polymer therapeutics with mucin. Biomacromolecules 11 (1) , pp. 120-125. 10.1021/bm9009667

Gumbleton, Mark

and Jones, Arwyn Tomos

2010. Cellular delivery of therapeutic macromolecules (CDTM) international Symposium 2010: lessons and progress from inter-disciplinary science. Drug Discovery Today 15 (23-24) , pp. 1079-180. 10.1016/j.drudis.2010.10.010

Gutteridge, Eleanor, Agrawal, Amit, Nicholson, Robert Ian, Cheung, Kwok Leung, Robertson, John and Gee, Julia Margaret Wendy

2010. The effects of gefitinib in tamoxifen-resistant and hormone-insensitive breast cancer: a phase II study. International Journal of Cancer 126 (8) , pp. 1806-1816. 10.1002/ijc.24884

Habashy, Hany Onsy, Powe, Desmond G., Staka, Cindy M., Rakha, Emad A., Ball, Graham, Green, Andrew R., Aleskandarany, Mohammed, Paish, E. Claire, Macmillan, R. Douglas, Nicholson, Robert Ian, Ellis, Ian O. and Gee, Julia Margaret Wendy

2010. Transferrin receptor (CD71) is a marker of poor prognosis in breast cancer and can predict response to tamoxifen. Breast Cancer Research and Treatment 119 (2) , pp. 283-293. 10.1007/s10549-009-0345-x

Hajjaj, F., Salek, Mir-saeed, Basra, M. K. A. and Finlay, Andrew Yule

2010. Nonclinical influences in dermatology decision making: a study of clinicians' perspective [Abstract]. British Journal of Dermatology 163 (S1) , pp. 44-45. 10.1111/j.1365-2133.2010.09728.x

Hajjaj, F. M., Salek, Mir-saeed, Basra, M and Finlay, Andrew Yule

2010. Clinical decision making in dermatology: observation of consultations and the patients' perspectives. Dermatology 221 (4) , pp. 331-341. 10.1159/000320124

Hajjaj, F. M., Salek, Mir-saeed, Basra, M. K. A. and Finlay, Andrew Yule

2010. Non-clinical influences on clinical decision-making: a major challenge to evidence-based practice. Journal of the Royal Society of Medicine 103 (5) , pp. 178-187. 10.1258/jrsm.2010.100104

Hajjaj, Fadi M, Salek, Mir-saeed, Basra, M. K. A. and Finlay, Andrew Yule

2010. Nonclinical influences, beyond diagnosis and severity, on clinical decision making in dermatology: understanding the gap between guidelines and practice. British Journal of Dermatology 163 (4) , pp. 789-799. 10.1111/j.1365-2133.2010.09868.x

Hall, A., Raja, N., Chamberlain, S. D., Gorovits, E., Henson, G. W., Hutchins, J. T., Muhammad, J., Patti, J., Vernachio, J., Wang, J., Madela, Karolina, Aljarah, Mohamed, Jones, Sarah Louise and McGuigan, Christopher

2010. Metabolite characterization of INX-189, a potent HCV inhibitor, in fresh human primary hepatocytes and human liver and kidney cell lines [abstract 1874]. Hepatology 52 (S1) , 1211A-1211A. 10.1002/hep.23996

Hamid, Shabaz A., Totzeck, Matthias, Drexhage, Christina, Thompson, Iain, Fowkes, Robert C., Rassaf, Tienush and Baxter, Gary Francis

2010. Nitric oxide/cGMP signalling mediates the cardioprotective action of adrenomedullin in reperfused myocardium. Basic Research in Cardiology 105 (2) , pp. 257-266. 10.1007/s00395-009-0058-7

Hampson, Frank C., Jolliffe, Ian G., Bakhtyari, Arash, Taylor, Glyn, Sykes, John, Johnstone, Lesley M. and Dettmar, Peter W. 2010. Alginate-antacid combinations: raft formation and gastric retention studies. Drug Development and Industrial Pharmacy 36 (5) , pp. 614-623. 10.3109/03639040903388290

Haq, Mohammed Inaam-ul 2010. Pain, sensation and biological responses following human skin puncture with microneedles. PhD Thesis, Cardiff University.

Hardwicke, Joseph, Moseley, Ryan

, Stephens, Philip

, Harding, Keith Gordon, Duncan, Ruth and Thomas, David William

2010. Bioresponsive dextrin-rhEGF conjugates: in vitro evaluation in models relevant to its proposed use as a treatment for chronic wounds. Molecular Pharmaceutics 7 (3) , pp. 699-707. 10.1021/mp9002656

Hausenloy, Derek J., Baxter, Gary Francis

, Bell, Robert, Bøtker, Hans Erik, Davidson, Sean M., Downey, James, Heusch, Gerd, Kitakaze, Masafumi, Lecour, Sandrine, Mentzer, Robert, Mocanu, Mihaela M., Ovize, Michel, Schulz, Rainer, Shannon, Richard, Walker, Malcolm, Walkinshaw, Gail and Yellon, Derek M. 2010. Translating novel strategies for cardioprotection: the Hatter Workshop Recommendations. Basic Research in Cardiology 105 (6) , pp. 677-686. 10.1007/s00395-010-0121-4

Henson, Alexander David 2010. Investigation of the effects of adenosine and purine nucleoside analogues on the viability of human breast cancer cells. PhD Thesis, Cardiff University.

Hiscox, Stephen Edward

, Barrett-Lee, Peter, Borley, Annabel Catherine and Nicholson, Robert Ian 2010. Combining Src inhibitors and aromatase inhibitors: A novel strategy for overcoming endocrine resistance and bone loss. European Journal of Cancer 46 (12) , pp. 2187-2195. 10.1016/j.ejca.2010.04.012

Hughes, Mary Louise

, Lo, T., Coulman, Sion

, Deslandes, Rhian

, Kell, Clare and John, David

2010. What makes a good lecturer? MPharm students’ views. International Journal of Pharmacy Practice 18 (s1) , pp. 29-30. 10.1111/j.2042-7174.2010.00027.x

Hutcheson, Iain Robert, Goddard, Lindy, Gee, Julia Margaret Wendy

, Barrow, Denise and Nicholson, Robert Ian 2010. Fulvestrant-induced expression of erbB3 and erbB4 sensitizes ER-positive breast cancer cells to heregulins [Abstract]. Breast Cancer Research 12 (S1) , P13. 10.1186/bcr2510

Ingram, R. J., Chu, K. K., Metan, G., Maillere, B., Doganay, M., Ozkul, Y., Dyson, H., Williamson, E. D., Baillie, Les

, Kim, L. U., Ascough, S., Sriskandan, S. and Altmann, D. M. 2010. An Epitope of Bacillus anthracis Protective Antigen That Is Cryptic in Rabbits May Be Immunodominant in Humans [Letter]. Infection and Immunity 78 (5) , pp. 2353-2354. 10.1128/IAI.00072-10

Ingram, Rebecca J., Metan, Gökhan, Maillere, Bernard, Doganay, Mehmet, Ozkul, Yusuf, Kim, Louise U., Baillie, Les

, Dyson, Hugh, Williamson, E. Diane, Chu, Karen K., Ascough, Stephanie., Moore, Steven, Huwar, Theresa B., Robinson, John H., Sriskandan, Shiranee and Altmann, Daniel M. 2010. Natural exposure to cutaneous anthrax gives long-lasting T cell immunity encompassing infection-specific epitopes. Journal of Immunology 184 (7) , pp. 3814-3821. 10.4049/jimmunol.0901581

James, K. Lynette, Davies, J. Graham, Kinchin, Ian, Patel, Jignesh P. and Whittlesea, Cate 2010. Understanding vs. competency: the case of accuracy checking dispensed medicines in pharmacy. Advances in Health Sciences Education 15 (5) , pp. 735-747. 10.1007/s10459-010-9234-7

Jasamai, Malina, Simons, Claire

and Balzarini, Jan 2010. Synthesis of Novel 6-Azapyrimidine Acyclic Nucleoside Analogues and Antiviral Evaluation. Nucleosides, Nucleotides & Nucleic Acids 29 (7) , pp. 535-541. 10.1080/15257771003781634

Jones, John Andrew 2010. Development of functional plastibodies. PhD Thesis, Cardiff University.

Jones, Arwyn Tomos

2010. Uptake and intracellular dynamics of proteins internalized by cell-penetrating peptides. Weissig, Volkmar and D'Souza, Gerard G. M., eds. Organelle-Specific Pharmaceutical Nanotechnology, Hoboken, NJ.: John Wiley & Sons, pp. 263-288. (10.1002/9780470875780.ch15)

Kadri, Hachemi 2010. Design, synthesis and biological evaluation of novel antitumour compounds. PhD Thesis, Cardiff University.

Khedr, Mohammed Abdou 2010. Computer-aided drug design and synthesis of novel antivirals. PhD Thesis, Cardiff University.

Knowlden, Janice Mary, Gee, Julia Margaret Wendy

, Barrow, Denise, Robertson, J. F., Ellis, I. O., Nicholson, Robert Ian and Hutcheson, Iain Robert 2010. O-36 Recruitment of insulin receptor substrate-1 by erbB3 impacts on IGF-IR signalling in oestrogen receptor-positive breast cancer cells [Abstract]. EJC Supplements 8 (6) , pp. 13-14. 10.1016/j.ejcsup.2010.06.037

Knowlden, Janice Mary, Gee, Julia Margaret Wendy

, Barrow, Denise, Robertson, J. F., Ellis, I. O., Nicholson, Robert Ian and Hutcheson, Iain Robert 2010. Recruitment of insulin receptor substrate-1 by erbB3 impacts on IGF-IR signalling in oestrogen receptor-positive breast cancer cells [Abstract]. Breast Cancer Research 12 (S1) , S15. 10.1186/bcr2546

Kolykhalov, A., Liu, Y., Bleiman, B., Patti, J., McGuigan, Christopher

and Vernachio, J. 2010. Characterization of in vitro selected hepatitis C virus replicon mutants resistant to the phosphoramidate analog of 2 '-C-Methylguanosine, INX-189 [Abstract]. Hepatology 52 (S1) , 1218A-1218A. 10.1002/hep.23997

Lane, Emma Louise

, Björklund, Anders, Dunnett, Stephen Bruce

and Winkler, Christian 2010. Neural grafting in Parkinson's disease: unraveling the mechanisms underlying graft-induced dyskinesia. Björklund, A. and Cenci, M. A., eds. Recent Advances in Parkinson’s Disease: Translational and Clinical Research, Progress in Brain Research, vol. 184. London: Elsevier, pp. 295-309. (10.1016/S0079-6123(10)84015-4)

Lane, Emma Louise

and Dunnett, Stephen Bruce

2010. Pretreatment with dopamine agonists influences L-dopa mediated rotations without affecting abnormal involuntary movements in the 6-OHDA lesioned rat. Behavioural Brain Research 213 (1) , pp. 66-72. 10.1016/j.bbr.2010.04.034

Lane, Emma Louise

and Smith, Gaynor A.

2010. Understanding graft-induced dyskinesia. Regenerative Medicine 5 (5) , pp. 787-797. 10.2217/rme.10.42

Lane, Jane

, Martin, Tracey

, McGuigan, Christopher

, Mason, Malcolm

and Jiang, Wen

2010. The differential expression of hCNT1 and hENT1 i n breast cancer and the possible impact on breast cancer therapy. Journal of Experimental Therapeutics and Oncology 8 (3) , pp. 203-210.

Lau, Wing Man

, White, Alex William

, Donaldson, M. and Heard, Charles Martin

2010. Histochemical visualisation of esterase activity in porcine ear skin. Journal of Pharmacy and Pharmacology 62 (6) , p. 798. 10.1211/jpp.62.06.0016

Lau, Wing Man

, White, Alex William

and Heard, Charles Martin

2010. Topical delivery of a naproxen-dithranol co-drug: in vitro skin penetration, permeation, and staining. Pharmaceutical Research 27 (12) , pp. 2734-2742. 10.1007/s11095-010-0274-8

Lee, L. M., Davison, Zoe and Heard, Charles Martin

2010. In vitro delivery of anti-breast cancer agents directly via the mammary papilla (nipple). International Journal of Pharmaceutics 387 (1-2) , pp. 161-166. 10.1016/j.ijpharm.2009.12.021

Luk, Yvonne, Allender, Christopher John and Wirth, Thomas

2010. Molecular imprinted polymers binding low functionality templates. Tetrahedron Letters 51 (45) , pp. 5883-5885. 10.1016/j.tetlet.2010.08.108

Martin, Christopher, Allender, Christopher John, Brain, Keith Roger, Hodson, D. and Birchall, James

2010. Biodegradable sugar glass microneedles for macromolecular drug delivery [Abstract]. Journal of Pharmacy and Pharmacology 62 (6) , p. 799. 10.1211/jpp.62.06.0016

Martínez-Barricarte, Rubén, Heurich, Meike

, Valdes-Cañedo, Francisco, Vazquez-Martul, Eduardo, Torreira, Eva, Montes, Tamara, Tortajada, Agustín, Pinto, Sheila, Lopez-Trascasa, Margarita, Morgan, Bryan Paul

, Llorca, Oscar, Harris, Claire Louise and Rodríguez de Córdoba, Santiago 2010. Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation. Journal of Clinical Investigation 120 (10) , pp. 3702-3712. 10.1172/JCI43343

McGuigan, Christopher

, Madela, Karolina, Aljarah, Mohamed, Gilles, Arnaud, Brancale, Andrea

, Zonta, Nicola, Chamberlain, Stanley, Vernachio, John, Hutchins, Jeff and Hall, Andrea 2010. Design, synthesis and evaluation of a novel double pro-drug: INX-08189. A new clinical candidate for hepatitis C virus. Biorganic and Medicinal Chemistry Letters 20 (16) , pp. 4850-4854. 10.1016/j.bmcl.2010.06.094

McGuigan, Christopher

, Gilles, Arnaud, Madela, Karolina, Aljarah, Mohamed, Holl, Sabrina, Jones, Sarah Louise, Vernachio, John, Hutchins, Jeff, Ames, Brenda, Bryant, K. Dawn, Gorovits, Elena, Ganguly, Babita, Hunley, Damound, Hall, Andrea, Kolykhalov, Alexander, Liu, Yule, Muhammad, Jerry, Raja, Nicholas, Walters, Robin, Wang, Jin, Chamberlain, Stanley and Henson, Geoffrey 2010. Phosphoramidate ProTides of 2'-C-Methylguanosine as highly potent inhibitors of hepatitis C virus. Study of their in vitro and in vivo properties. Journal of Medicinal Chemistry 53 (13) , pp. 4949-4957. 10.1021/jm1003792

Mehellou, Youcef

2010. Phosphoramidate Prodrugs Deliver with Potency Against Hepatitis C Virus. ChemMedChem 5 (11) , pp. 1841-1842. 10.1002/cmdc.201000310

Mehellou, Youcef

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2010. The design, synthesis and antiviral evaluation of a series of 5-trimethylsilyl-1-β-D-(arabinofuranosyl)uracil phosphoramidate ProTides. Antiviral Chemistry & Chemotherapy 20 (4) , pp. 153-160. 10.3851/IMP1476

Mehellou, Youcef

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Mehellou, Youcef

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2010. Phosphoramidates of 2′-β-d-arabinouridine (AraU) as phosphate prodrugs; design, synthesis, in vitro activity and metabolism. Bioorganic & Medicinal Chemistry 18 (7) , pp. 2439-2446. 10.1016/j.bmc.2010.02.059

Morgan, Alwena Haf, Hammond, Victoria Jayne, Morgan, Lloyd, Thomas, Christopher P.

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2010. Quantitative assays for esterified oxylipins generated by immune cells. Nature Protocols 5 (12) , pp. 1919-1931. 10.1038/nprot.2010.162

Morgan-Davies, Alwena H. 2010. Generation and metabolism of 12/15-LOX esterified products. PhD Thesis, Cardiff University.

Natividad, Gaudencio M. 2010. Isolation and chemical and pharmacological characterization of potential trace amine-associated receptor antagonist from plant sources. PhD Thesis, Cardiff University.

Ng, K. W., Pearton, Marc, Allender, Christopher John, Morrissey, A., McLoughlin, P. and Birchall, James Caradoc

2010. Biodegradable microneedles for intra-epidermal vaccination [Abstract]. Journal of Pharmacy and Pharmacology 62 (6) , p. 798. 10.1211/jpp.62.06.0016

Nikander, Kurt, Prince, Ivan, Coughlin, Steven, Warren, Simon J. and Taylor, Glyn 2010. Mode of breathing- tidal or slow and deep-through the I-neb Adaptive Aerosol Delivery (AAD) System affects lung deposition of Tc-99m-DTPA. Journal of Aerosol Medicine and Pulmonary Drug Delivery 23 (S1) , S37-S43. 10.1089/jamp.2009.0786

O'Connor, Emer 2010. Ageing, motion sensitivity and eye movement. PhD Thesis, Cardiff University.

Ovize, M., Baxter, Gary Francis

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Patton, John S., Brain, Joseph D., Davies, Lee A., Fiegel, Jennifer, Gumbleton, Mark

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Pearton, Marc, Kang, S. M., Song, J. M., Anstey, Alexander Vincent

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2010. Changes in human Langerhans cells following intradermal injection of influenza virus-like particle vaccines. PLoS ONE 5 (8) , e12410. 10.1371/journal.pone.0012410

Pearton, Marc, Kang, S. M., Song, J. M., Kim, Y. C., Quan, F. S., Ivory, M., Prausnitz, M. R., Compans, R. W. and Birchall, James Caradoc

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Pearton, Marc, Kang, Sang-Moo, Song, Jae-Min, Kim, Yeu-Chun, Quan, Fu-Shi, Anstey, Alexander Vincent

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2010. Influenza virus-like particles coated onto microneedles can elicit stimulatory effects on Langerhans cells in human skin. Vaccine 28 (37) , pp. 6104-6113. 10.1016/j.vaccine.2010.05.055

Perni, Stefano, Prokopovich, Polina

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Pinto, Federica, Maillard, Jean Yves

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Pinto, Federica, Maillard, Jean-Yves

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Porasuphatana, S., Cao, G. L., Tsai, P., Tavakkoli, F., Huwar, T., Baillie, Les

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Prokopovich, Polina

and Perni, S. 2010. Prediction of the frictional behavior of mammalian tissues against biomaterials. Acta Biomaterialia 6 (10) , pp. 4052-4059. 10.1016/j.actbio.2010.05.007

Prokopovich, Polina

, Perni, S., Piccirillo, C., Pratten, J., Parkin, I. P. and Wilson, M. 2010. Frictional Properties of Light-activated Silicone and Polyurethane against blood vessels. Journal of Materials Science: Materials in Medicine 21 (2) , pp. 815-821. 10.1007/s10856-009-3882-2

Prokopovich, Polina

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Prokopovich, Polina

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Prokopovich, Polina

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Ramirez, K., Ditamo, Y., Galen, J. E., Baillie, Les

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Rapport, Frances, Doel, Marcus A., Hutchings, Hayley A., Jerzembek, Gabrielle Sophia, John, David Neale

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Rapport, Frances, Doel, Marcus A., Hutchings, Hayley A., Wright, Sarah, Wainwright, Paul, John, David Neale

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Rautureau, Y., Gowers, I., Wheeler-Jones, C. P. D. and Baxter, Gary Francis

2010. C-type natriuretic peptide regulation of guanosine-3′,5′-cyclic monophosphate production in human endothelial cells. Autonomic and Autacoid Pharmacology 30 (3) , pp. 185-192. 10.1111/j.1474-8673.2009.00449.x

Robertson, J. F. R., Dixon, J. M., Sibbering, D. M., Jahan, A., Ellis, I. O., Channon, E., Nicholson, Robert Ian and Gee, Julia Margaret Wendy

2010. Biological activity of a combination of fulvestrant 500 mg (F500) plus anastrozole versus F500 alone or anastrozole alone as neoadjuvant treatment for breast cancer [Abstract]. EJC Supplements 8 (3) , p. 63. 10.1016/S1359-6349(10)70050-1

Romagnoli, Romeo, Baraldi, Pier Giovanni, Carrion, Maria Dora, Cruz-Lopez, Olga, Tolomeo, Manlio, Grimaudo, Stefania, Di Cristina, Antonietta, Pipitone, Maria Rosaria, Balzarini, Jan and Brancale, Andrea

2010. Substituted 2-(3′,4′,5′-trimethoxybenzoyl)-benzo[b]thiophene derivatives as potent tubulin polymerization inhibitors. Bioorganic & Medicinal Chemistry 18 (14) , pp. 5114-5122. 10.1016/j.bmc.2010.05.068

Romagnoli, Romeo, Baraldi, Pier Giovanni, Cruz-Lopez, Olga, Lopez Cara, Carlota, Carrion, Maria Dora, Brancale, Andrea

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Rowntree, J. K., Cowan, R. S., Leggett, Mark J., Ramsay, M. M. and Fay, M. F. 2010. Which moss is which? Identification of the threatened moss Orthodontium gracile using molecular and morphological techniques. Conservation Genetics 11 (3) , pp. 1033-1042. 10.1007/s10592-009-9948-3

Salek, Mir-saeed, Kamau, P., McAuslane, N, Pichler, F. and Walker, Stuart 2010. Is simultaneous submission and regulatory approval a reality towards faster patient access to medicines in the ICH region and beyond? [Abstract]. Pharmacy World and Science 32 (2) , pp. 218-219. 10.1007/s11096-010-9378-9

Salek, Mir-saeed, Mahbouba, T., Basra, M., Golicks, C. and Finlay, Andrew

2010. Adolescents with skin diseases: the forgotten group [Abstract]. Pharmacy World and Science 32 (2) , pp. 240-241. 10.1007/s11096-010-9378-9

Salek, Mir-saeed, Modi, A, Hansen, R. A. and Wei, D. 2010. Reducing repeat medication errors in nursing homes [Abstract]. Pharmacy World and Science 32 (2) , pp. 242-243. 10.1007/s11096-010-9378-9

Salek, Mir-saeed, Sanghvi, S., Rodgers, J. and Montague, D. 2010. Evaluation of the use and efficacy of heparin nomograms in a university-teaching hospital in North Carolina [Abstract]. Pharmacy World and Science 32 (2) , p. 263. 10.1007/s11096-010-9378-9

Salek, Mir-saeed, Sturkey, R., Basra, M. and Finlay, Andrew Yule

2010. Assessment of the clinical meaningfulness of change in dermatology life quality index scores [Abstract]. Pharmacy World and Science 32 (2) , p. 236. 10.1007/s11096-010-9378-9

Samah, Nor Abu, Williams, Nicholas and Heard, Charles Martin

2010. Nanogel particulates located within diffusion cell receptor phases following topical application demonstrates uptake into and migration across skin. International Journal of Pharmaceutics 401 (1-2) , pp. 72-78. 10.1016/j.ijpharm.2010.08.011

Searby, Caroline, Heard, Charles Martin

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2010. Sonic hedgehog is not enough to create basal cell carcinoma in vitro. British Journal of Dermatology 162 (4) , p. 923. 10.1111/j.1365-2133.2010.09700.x

Shetty, Hamsaraj Gundal Mahabala, Campbell, Ian A. and Routledge, Philip Alexander 2010. Venous thromboembolism in the elderly. Fillit, Howard M., Rockwood, Kenneth and Woodhouse, Kenneth, eds. Brocklehurst's Textbook of Geriatric Medicine and Gerontology. 7th ed., Philadelphia, PA: Elsevier, pp. 356-361. (10.1016/B978-1-4160-6231-8.10048-0)

Singka, Gillian S. L., Abu Samah, Nor H., Zulfakar, Mohd, Yurdasiper, A. and Heard, Charles Martin

2010. Enhanced topical delivery and anti-inflammatory activity of methotrexate from an activated nanogel. European Journal of Pharmaceutics and Biopharmaceutics 76 (2) , pp. 275-281. 10.1016/j.ejpb.2010.06.014

Smith, Nicola and Broadley, Kenneth John

2010. Adenosine receptor subtypes in airways responses of sensitized guinea-pigs to inhaled ovalbumin. Pulmonary Pharmacology and Therapeutics 23 (4) , pp. 355-364. 10.1016/j.pupt.2010.03.010

Song, J. M., Kim, Y. C., Lipatov, A. S., Pearton, Marc, Davis, C. T., Yoo, D. G., Park, K. M., Chen, L. M., Quan, F. S., Birchall, James Caradoc

, Donis, R. O., Prausnitz, M. R., Compans, R. W. and Kang, S. M. 2010. Microneedle delivery of H5N1 influenza virus-like particles to the skin induces long-lasting B- and T-Cell responses in mice. Clinical and Vaccine Immunology 17 (9) , pp. 1381-1389. 10.1128/CVI.00100-10

Stewart, Derek, Cunningham, I. T. Scott, Hansford, Denise, John, David Neale

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Sweeney, Michele, Watkins, Catherine Louise, Jones, Arwyn Tomos

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Thomas, Nicholas B. P., Hutcheson, Iain Robert, Campbell, Lee, Gee, Julia Margaret Wendy

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2010. Growth of hormone-dependent MCF-7 breast cancer cells is promoted by constitutive caveolin-1 whose expression is lost in an EGF-R-mediated manner during development of tamoxifen resistance. Breast Cancer Research and Treatment 119 (3) , pp. 575-591. 10.1007/s10549-009-0355-8

Thomas, V., McDonnell, G., Denyer, Stephen Paul and Maillard, Jean Yves

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Thomas, Vincent, McDonnell, Gerald, Denyer, Stephen Paul and Maillard, Jean-Yves

2010. Free-living amoebae and their intracellular pathogenic microorganisms: risks for water quality. FEMS Microbiology Reviews 34 (3) , pp. 231-259. 10.1111/j.1574-6976.2009.00190.x

Trippier, Paul C., Balzarini, Jan and McGuigan, Christopher

2010. Phenylboronic-acid-based carbohydrate binders as antiviral therapeutics: bisphenylboronic acids. Antiviral Chemistry and Chemotherapy 21 (3) , pp. 129-142. 10.3851/IMP1707

Trippier, Paul C. and McGuigan, Christopher

2010. Boronic acids in medicinal chemistry: anticancer, antibacterial and antiviral applications. MedChemComm 1 (3) , pp. 183-198. 10.1039/c0md00119h

Trippier, Paul Charles, McGuigan, Christopher

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Turner, Dawn Louise, Ferrari, Nicolay, Ford, William Richard

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2010. TPI 1020, a novel anti-inflammatory, nitric oxide donating compound, potentiates the bronchodilator effects of salbutamol in conscious guinea-pigs. European Journal of Pharmacology 641 (2-3) , pp. 213-219. 10.1016/j.ejphar.2010.05.025

Vanpouille, C., Lisco, A., Derudas, Marco, Saba, E., Grivel, J. C., Brichacek, B., Scrimieri, F., Schinazi, R., Schols, D., McGuigan, Christopher

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Vercauteren, Dries, Vandenbroucke, Roosmarijn E., Jones, Arwyn Tomos

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Vernachio, J., Bryant, D., Chamberlain, S. D., Gorovits, E., Ganguly, B. S., Hall, A., Henson, G. W., Hunley, D. S., Hutchins, J. T., Muhammad, J., Patti, J., Walters, C. R., Wang, J., Madela, Karolina, Aljarah, Mohamed, Jones, Sarah Louise and McGuigan, Christopher

2010. In vitro and in vivo metabolism of INX-189, a potent HCV inhibitor, in rat and cynomolgus monkey hepatocytes [Abstract]. Hepatology 52 (S1) , 1218A-1219A. 10.1002/hep.23997

Walker, Roger 2010. Editorial: Pharmacy research and a fair society. International Journal of Pharmacy Practice 18 (2) , pp. 67-68. 10.1211/ijpp/18.02.0001

Walker, Roger and Hinchliffe, Anne 2010. Prescribing and sale of ophthalmic chloramphenicol following reclassification to over-the-counter availability. International Journal of Pharmacy Practice 18 (5) , pp. 269-274. 10.1111/ijpp.18.05.00046.x

Watkins, Catherine Louise, Ochonogor, O. and Jones, A. T. 2010. Utilising the fluorescent properties of Laurdan to study plasma membrane fluidity in cells treated with the cell penetrating peptide R8. Drug Discovery Today 15 (23-24) , p. 1106.

Weaver, Benjamin P., Zhang, Yuxia, Hiscox, Stephen Edward

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Weekes, Ashley Ann 2010. New methods for synthesis of substituted 2-phenylbenzothiazoles. PhD Thesis, Cardiff University.

Weekes, Ashley Ann, Dix, Matthew C., Bagley, Mark Christopher and Westwell, Andrew D.

2010. Rapid and convenient thermal or microwave-assisted synthesis of substituted 2-Phenylbenzothiazoles. Synthetic Communications 40 (20) , pp. 3027-3032. 10.1080/00397910903353739

Ziedan, Noha I., Stefanelli, Fabio, Fogli, Stefano and Westwell, Andrew D.

2010. Design, synthesis and pro-apoptotic antitumour properties of indole-based 3,5-disubstituted oxadiazoles. European Journal of Medicinal Chemistry 45 (10) , pp. 4523-4530. 10.1016/j.ejmech.2010.07.012

Zonta, Nicola, Coluccia, A. and Brancale, Andrea

2010. Advanced in silico approaches in antiviral research. Antiviral Chemistry and Chemotherapy 20 (4) , pp. 147-151. 10.3851/IMP1500

Zulfakar, Modh Hanif, Abdelouahab, Nassima and Heard, Christopher Martin

2010. Enhanced topical delivery and ex vivo anti-inflammatory activity from a betamethasone dipropionate formulation containing fish oil. Inflammation Research 59 (1) , pp. 23-30. 10.1007/s00011-009-0065-z

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