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Al Soraj, M., He, Lin, Peynshaert, Karen, Cousaert, Julie, Vercauteren, D., Braeckmans, K., De Smedt, S. C. and Jones, Arwyn Tomos ORCID: https://orcid.org/0000-0003-2781-8905 2012. siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat. Journal of Controlled Release 161 (1) , pp. 132-141. 10.1016/j.jconrel.2012.03.015 |
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Baxter, S, Lambert, AR, Kuhar, R, Jarjour, J, Kulshina, N, Parmeggiani, F ORCID: https://orcid.org/0000-0001-8548-1090, Danaher, P, Gano, J, Baker, D, Stoddard, B and Scharenberg, A 2012. Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases. Nucleic Acids Research 40 (16) , pp. 7985-8000. 10.1093/nar/gks502 |
Bice, Justin S.
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Cardioprotection afforded by targeting guanylyl cyclase during early reperfusion.
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Birchall, James Cardaoc ORCID: https://orcid.org/0000-0001-8521-6924 2012. Overcoming the stratum corneum barrier: microneedle delivery of macromolecules and vaccines [Abstract]. International Journal of Cosmetic Science 34 (4) , p. 361. 10.1111/j.1468-2494.2012.00720.x |
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Bourdin, Claire
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Antiviral drug design, dynthesis and biological evaluation
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Burgess, Caroline, Cowie, Luke and Gulliford, Martin 2012. Patients' perceptions of error in long-term illness care: qualitative study. Journal of Health Services Research and Policy 17 (3) , pp. 181-187. 10.1258/jhsrp.2012.011122 |
Burley, D. S., Cox, C. D., Wann, K. T. and Baxter, Gary Francis ORCID: https://orcid.org/0000-0002-7887-6841 2012. P541: Natriuretic peptide inhibition of sarcolemmal atp-sensitive potassium channel in rat cardiomyocytes [Abstract]. Cardiovascular Research 93 (S1) , S105-S106. 10.1093/cvr/cvr336 |
Caldon, C. Elizabeth, Sergio, C. Marcelo, Kang, Jian, Muthukaruppan, Anita, Boersma, Marikje N., Stone, Andrew, Barraclough, Jane, Lee, Christine S., Black, Michael A., Miller, Lance D., Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015, Nicholson, Robert Ian, Sutherland, Robert L., Print, Crispin G. and Musgrove, Elizabeth A. 2012. Cyclin E2 overexpression is associated with endocrine resistance but not insensitivity to CDK2 inhibition in human breast cancer cells. Molecular Cancer Therapeutics 11 (7) , pp. 1488-1499. 10.1158/1535-7163.MCT-11-0963 |
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Design, synthesis and biological evaluation of
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Castell, Oliver Kieran ORCID: https://orcid.org/0000-0002-6059-8062, Berridge, James and Wallace, Mark I. 2012. Quantification of membrane protein inhibition by optical ion flux in a droplet interface bilayer array. Angewandte Chemie - International Edition 51 (13) , pp. 3134-3138. 10.1002/anie.201107343 |
Chen, Shengxi, Fahmi, Nour Eddine, Nangreave, Ryan C., Mehellou, Youcef ORCID: https://orcid.org/0000-0001-5720-8513 and Hecht, Sidney M. 2012. Synthesis of pdCpAs and transfer RNAs activated with thiothreonine and derivatives. Bioorganic & Medicinal Chemistry 20 (8) , pp. 2679-2689. 10.1016/j.bmc.2012.02.024 |
Cox, Charles
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Structural and functional studies of bacterial mechanosensitive channels.
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Derudas, Marco and McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X 2012. Serendipity and VZV drug discovery. Drug Discovery Today: Technologies 9 (3) , e177-e181. 10.1016/j.ddtec.2011.11.001 |
Devadason, Sunalene G., Chan, Hak-Kim, Haeussermann, Sabine, Kietzig, Claudius, Kuehl, Philip J., Newman, Stephen, Sommerer, Knut and Taylor, Glyn 2012. Validation of Radiolabeling of Drug Formulations for Aerosol Deposition Assessment of Orally Inhaled Products. Journal of Aerosol Medicine and Pulmonary Drug Delivery 25 (S1) , S6-S9. 10.1089/jamp.2012.1Su3 |
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Finlay, Andrew Yule ORCID: https://orcid.org/0000-0003-2143-1646, Basra, Mohamed K. A., Piguet, Vincent and Salek, Mir-saeed 2012. Dermatology Life Quality Index (DLQI): A Paradigm Shift to Patient-Centered Outcomes [Letter]. Journal of Investigative Dermatology 132 (10) , pp. 2464-2465. 10.1038/jid.2012.147 |
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Gangadhara, Sharath, Barrett-Lee, Peter, Nicholson, Robert and Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702 2012. Pro-metastatic tumor-stroma interactions in breast cancer. Future Oncology 8 (11) , pp. 1427-1442. 10.2217/fon.12.134. |
Golics, Catherine Jane, Basra, Mohamed K. A., Salek, Mir-saeed and Finlay, Andrew Yule ORCID: https://orcid.org/0000-0003-2143-1646 2012. The Family Reported Outcome Measure (c): initial validation of a generic QoL measure for family members of patients with chronic medical conditions [Abstract]. Journal of Investigative Dermatology 132 (S2) , S72. 10.1038/jid.2012.300 |
Gomaa, Mohamed S., Bridgens, C. E., Illingworth, N. A., Veal, G. J., Redfern, C. P. F., Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Armstrong, J. L. and Simons, Claire ORCID: https://orcid.org/0000-0002-9487-1100 2012. Novel retinoic acid 4-hydroxylase (CYP26) inhibitors based on a 3-(1H-imidazol- and triazol-1-yl)-2,2-dimethyl-3-(4-(phenylamino)phenyl)propyl scaffold. Bioorganic & Medicinal Chemistry 20 (14) , pp. 4201-4207. 10.1016/j.bmc.2012.05.076 |
Gomaa, Mohamed S., Lim, Andrew S. T., Lau, Sze C. W., Watts, Ann-Marie, Illingworth, N. A., Bridgens, C. E., Veal, G. J., Redfern, C. P. F., Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419, Armstrong, J. L. and Simons, Claire ORCID: https://orcid.org/0000-0002-9487-1100 2012. Synthesis and CYP26A1 inhibitory activity of novel methyl 3-[4-(arylamino)phenyl]-3-(azole)-2,2-dimethylpropanoates. Bioorganic & Medicinal Chemistry 20 (20) , pp. 6080-6088. 10.1016/j.bmc.2012.08.044 |
Groves, Rachel Beth, Coulman, Sion ORCID: https://orcid.org/0000-0002-1277-7584, Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 and Evans, Samuel Lewin ORCID: https://orcid.org/0000-0003-3664-2569 2012. Quantifying the mechanical properties of human skin to optimise future microneedle device design. Computer Methods in Biomechanics and Biomedical Engineering 15 (1) , pp. 73-82. 10.1080/10255842.2011.596481 |
Gruden, Marina A., Yanamandra, Kiran, Kucheryanu, Valery G., Bocharova, Olga R., Sherstnev, Vladimir V., Morozova-Roche, Ludmilla A. and Sewell, Robert David Edmund 2012. Correlation between protective immunity to alpha-synuclein aggregates, oxidative stress and inflammation. Neuroimmunomodulation 19 (6) , pp. 334-342. 10.1159/000341400 |
Harris, Claire Louise, Heurich, Meike ORCID: https://orcid.org/0000-0003-0105-2702, Rodriguez de Cordoba, Santiago and Morgan, Bryan Paul ORCID: https://orcid.org/0000-0003-4075-7676 2012. The complotype: dictating risk for inflammation and infection. Trends in Immunology 33 (10) , pp. 513-521. 10.1016/j.it.2012.06.001 |
Hayes, Edward
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Acquired tamoxifen resistance and promotion of angiogenic responses in breast cancer.
PhD Thesis,
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Hendley, Rhiannon
2012.
Identification of Lyn kinase as a therapeutic target for
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PhD Thesis,
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Hiscox, Stephen Edward ORCID: https://orcid.org/0000-0003-0105-2702, Baruha, Bedanta, Smith, Chris, Bellerby, Rebecca, Goddard, Lindy, Jordan, Nicola Jane, Poghosyan, Zaruhi ORCID: https://orcid.org/0000-0003-4966-7618, Nicholson, Robert Ian, Barrett-Lee, Peter and Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015 2012. Overexpression of CD44 accompanies acquired tamoxifen resistance in MCF7 cells and augments their sensitivity to the stromal factors, heregulin and hyaluronan. BMC Cancer 12 , 458. 10.1186/1471-2407-12-458 |
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Joshi, Lovleen Tina
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Pathogenicity & a bedside real-time detection assay for
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Kalyuga, Maria, Gallego-Ortega, David, Lee, Heather J., Roden, Daniel L., Cowley, Mark J., Caldon, C. Elizabeth, Stone, Andrew, Allerdice, Stephanie L., Valdes-Mora, Fatima, Launchbury, Rosalind, Statham, Aaron L., Armstrong, Nicola, Alles, M. Chehani, Young, Adelaide, Egger, Andrea, Au, Wendy, Piggin, Catherine L, Evans, Cara J., Ledger, Anita, Brummer, Tilman, Oakes, Samantha R., Kaplan, Warren, Gee, Julia Margaret Wendy ORCID: https://orcid.org/0000-0001-6483-2015, Nicholson, Robert Ian, Sutherland, Robert L., Swarbrick, Alexander, Naylor, Matthew J., Clark, Susan J., Carroll, Jason S. and Ormandy, Christopher J. 2012. ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. PLoS Biology 10 (12) , e1001461. 10.1371/journal.pbio.1001461 |
Kamudoni, Paul, Salek, Mir-saeed, Mueller, B. and Mueller, C. 2012. Hyperhidrosis Quality of Life Index (Hidroqol (c)): a novel patient reported outcome measure in hyperhidrosis [Abstract]. Journal of Investigative Dermatology 132 (S2) , S73. 10.1038/jid.2012.300 |
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Li, Bo
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The role of BK channel in cellular proliferation and differentiation in human osteoblast and osteoblast-like cells.
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Lindgren, Hanna Sofia and Lane, Emma Louise ORCID: https://orcid.org/0000-0001-8800-3764 2012. Rodent models of l-DOPA-induced dyskinesia. Neuromethods 61 , pp. 337-351. 10.1007/978-1-61779-298-4_18 |
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Understanding the iInteractions of hydrogen peroxide with macromolecules and microbial components.
PhD Thesis,
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The involvement of CaMKII in myocardial ischaemia-reperfusion injury.
PhD Thesis,
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Madela, Karolina
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Design, synthesis and biological evaluation of novel
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PhD Thesis,
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Development, characterisation and evaluation of sugar glass microneedles.
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Martin, Christopher, Allender, Christopher John, Brain, Keith Roger, Morrissey, A. and Birchall, James Caradoc ORCID: https://orcid.org/0000-0001-8521-6924 2012. Low temperature fabrication of biodegradable sugar glass microneedles for transdermal drug delivery applications. Journal of Controlled Release 158 (1) , pp. 93-101. 10.1016/j.jconrel.2011.10.024 |
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Perni, Stefano, Kong, Michael G. and Prokopovich, Polina ORCID: https://orcid.org/0000-0002-5700-9570 2012. Cold atmospheric pressure gas plasma enhances the wear performance of ultra-high molecular weight polyethylene. Acta Biomaterialia 8 (3) , pp. 1357-1365. 10.1016/j.actbio.2011.12.007 |
Prokopovich, Polina ORCID: https://orcid.org/0000-0002-5700-9570 2012. A dimensionless analysis of the effect of material and surface properties on adhesion. applications to medical device design. Starov, Victor and Griffiths, Peter, eds. Progress in Colloid and Polymer Sceinve, Vol. 139. Springer Verlag, pp. 59-65. (10.1007/978-3-642-28974-3_11) |
Rauf, Khalid, Subhan, Fazal and Sewell, Robert David Edmund 2012. A Bacoside containing Bacopa monnieri extract reduces both morphine hyperactivity plus the elevated striatal dopamine and serotonin turnover. Phytotherapy Research 26 (5) , pp. 758-763. 10.1002/ptr.3631 |
Reichen, C, Varadamsetty, G, Tremmel, D, Parmeggiani, F ORCID: https://orcid.org/0000-0001-8548-1090, Honegger, A, Fleishmann, S, Baker, D, Madhurantakam, C, Mittl, P, Gruetter, M and Plueckthun, A 2012. Design and Selection of Armadillo Repeat Proteins: A novel technology for modular peptide recognition. Protein Science 21 (Supple) , p. 82. |
Ricci, Antonio, Anthopoulos, Athanasios, Massarotti, A., Grimstead, Ian John and Brancale, Andrea ORCID: https://orcid.org/0000-0002-9728-3419 2012. Haptic-driven applications to molecular modeling: state-of-the-art and perspectives. Future Medicinal Chemistry 4 (10) , pp. 1219-1228. 10.4155/fmc.12.60 |
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Routledge, Philip Alexander 2012. A national in-patient prescription chart: the experience in Wales 2004-2012. British Journal of Clinical Pharmacology 74 (4) , pp. 561-565. 10.1111/j.1365-2125.2012.04283.x |
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Cellular basis of neurodegeneration - The possible role of ryanodine receptor and potassium channel in neuronal death and neuroprotection.
PhD Thesis,
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