ORCA
Online Research @ Cardiff
Browse by All Cardiff Authors
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Up a levelNumber of items: 119.
Koftori, Danai, Kaur, Charandeep, Mora Bitria, Laura, Zhang, Yan, Hadcocks, Linda, Yan, Ada W. C., Burzynski, Piotr F., Ladell, Kristin  ORCID: https://orcid.org/0000-0002-9856-2938, Speiser, Daniel E., Pollock, Katrina M., Macallan, Derek and Asquith, Becca
2025.
Two distinct subpopulations of human stem-like memory T cells exhibit complementary roles in self-renewal and clonal longevity.
PLoS Biology
23
(6)
, e3003179.
10.1371/journal.pbio.3003179
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Gao, Yu, Curtis, Cai, Adamo, Sarah, Biteus, Elsa, Kamal, Habiba, Dager, Lena, Miners, Kelly L., Llewellyn-Lacey, Sian, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Amratia, Pragati, Bentley, Kirsten ORCID: https://orcid.org/0000-0002-6619-2098, Kollnberger, Simon, Wu, Jinghua, Akhirunnesa, Mily, Jones, Samantha, Julin, Per, Lidman, Christer, Stanton, Richard ORCID: https://orcid.org/0000-0002-6799-1182, Goepfert, Paul, Peluso, Michael, Deeks, Steven, Davies, Helen, Aleman, Soo, Buggert, Marcus and Price, David ORCID: https://orcid.org/0000-0001-9416-2737
2025.
Identification of soluble biomarkers that associate with distinct manifestations of long COVID.
Nature Immunology
26
, 692–705.
10.1038/s41590-025-02135-5
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Lukyanov, Daniil K., Kriukova, Valeriia V., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Shagina, Irina A., Staroverov, Dmitry B., Minasian, Bella E., Fedosova, Anna S., Shelyakin, Pavel, Suchalko, Oleg N., Komkov, Alexander Y., Blagodatskikh, Konstantin A., Miners, Kelly L., Britanova, Olga V., Franke, Andre, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and Chudakov, Dmitry M.
2025.
Repertoire-based mapping and time-tracking of T helper cell subsets in scRNA-Seq.
Frontiers in Immunology
16
, 1536302.
10.3389/fimmu.2025.1536302
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Mora-Bitria, Laura, Debebe, Bisrat J., Miners, Kelly L., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Kaur, Charandeep, Traherne, James A., Jiang, Wei, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Hadcocks, Linda, McQuibban, Nicholas A. R., Trowsdale, John, Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845, Pontikos, Nikolas, Niederalt, Christoph and Asquith, Becca
2024.
Inhibitory KIRs decrease HLA class II-mediated protection in Type 1 Diabetes.
PLoS Genetics
20
(12)
, e1011456.
10.1371/journal.pgen.1011456
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Giannoni, Eric, Sanchez, Guillem Sanchez, Verdebout, Isoline, Papadopoulou, Maria, Rezwani, Moosa, Ahmed, Raya, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly L., McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934, Fraser, Donald J. ORCID: https://orcid.org/0000-0003-0102-9342, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348, Study, Swiss Pediatric Sepsis, Agyeman, Philipp K.A., Schlapbach, Luregn and Vermijlen, David
2024.
Sepsis shapes the human γδ TCR repertoire in an age- and pathogen-dependent manner.
European Journal of Immunology
54
(10)
, 2451190.
10.1002/eji.202451190
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Dallan, Beatrice, Proietto, Davide, De Laurentis, Martina, Gallerani, Eleonora, Martino, Mara, Ghisellini, Sara, Zurlo, Amedeo, Volpato, Stefano, Govoni, Benedetta, Borghesi, Michela, Albanese, Valentina, Appay, Victor, Bonnini, Stefano, Llewellyn-Lacey, Sian, Pacifico, Salvatore, Grumiro, Laura, Brandolini, Martina, Semprini, Simona, Sambri, Vittorio, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Parry, Helen M., Moss, Paul A. H., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Barbieri, Elena, Bernardi, Tatiana, Boni, Michela, Dall?Olio, Linda, De Laurentis, Martina, Fiorini, Caterina, Fiorini, Michele, Govoni, Maurizio, Neri, Margherita, Palma, Fabio, Romagnoni, Franco, Caputo, Antonella, Gavioli, Riccardo and Nicoli, Francesco
2024.
Age differentially impacts adaptive immune responses induced by adenoviral versus mRNA vaccines against COVID-19.
Nature Aging
4
(8)
, 1121–1136.
10.1038/s43587-024-00644-w
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Baillie, Kirsten, Davies, Helen E., Keat, Samuel B. K., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly L., Jones, Samantha A., Mellou, Ermioni, Toonen, Erik J. M., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Morgan, B. Paul ORCID: https://orcid.org/0000-0003-4075-7676 and Zelek, Wioleta M.
2024.
Complement dysregulation is a prevalent and therapeutically amenable feature of long COVID.
Med
5
(3)
, pp. 239-253.
10.1016/j.medj.2024.01.011
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Roger, Laureline, Miners, Kelly L., Leonard, Louise, Grimstead, Julia W., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467 and Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938
2023.
T cell memory revisited using single telomere length analysis.
Frontiers in Immunology
14
, 1100535.
10.3389/fimmu.2023.1100535
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Rubina, Anzelika, Patel, Mihil, Nightingale, Katie, Potts, Martin, Fielding, Ceri A. ORCID: https://orcid.org/0000-0002-5817-3153, Kollnberger, Simon, Lau, Betty, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly L., Nichols, Jenna, Nobre, Luis, Roberts, Dawn, Trinca, Terrence M., Twohig, Jason P., Vlahava, Virginia-Maria, Davison, Andrew J., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Tomasec, Peter, Wilkinson, Gavin W. G., Weekes, Michael P., Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182 and Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964
2023.
ADAM17 targeting by human cytomegalovirus remodels the cell surface proteome to simultaneously regulate multiple immune pathways.
Proceedings of the National Academy of Sciences
120
(33)
, e2303155120.
10.1073/pnas.2303155120
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Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly L, Marsden, Morgan, Chapman, Lucy, Cardus Figueras, Anna, Scott, Jake, Andrews, Robert, Clare, Simon, Kriukova, Valeriia V, Lupyr, Ksenia R, Britanova, Olga V, Withers, David R, Jones, Simon A ORCID: https://orcid.org/0000-0001-7297-9711, Chudakov, Dmitriy M, Price, David A ORCID: https://orcid.org/0000-0001-9416-2737 and Humphreys, Ian R ORCID: https://orcid.org/0000-0002-9512-5337
2023.
Inhibitory IL-10-producing CD4+ T cells are T-bet-dependent and facilitate cytomegalovirus persistence via coexpression of arginase-1.
eLife
12
, e79165.
10.7554/eLife.79165
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Chen, Yi-Ling, Ng, Jessica Soo Weei, Ottakandathil Babu, Rosana, Woo, Jeongmin, Nahler, Janina, Hardman, Clare S., Kurupati, Prathiba, Nussbaum, Lea, Gao, Fei, Dong, Tao, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Duncan, David A., Johnson, David, Gileadi, Uzi, Koohy, Hashem and Ogg, Graham S.
2023.
Group A Streptococcus induces CD1a-autoreactive T cells and promotes psoriatic inflammation.
Science Immunology
8
(84)
, eadd9232.
10.1126/sciimmunol.add9232
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Ciacchi, Lisa, van de Garde, Martijn D.B., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Farenc, Carine, Poelen, Martien C.M., Miners, Kelly L., Llerena, Carmen, Reid, Hugh H., Petersen, Jan, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Rossjohn, Jamie ORCID: https://orcid.org/0000-0002-2020-7522 and van Els, Cécile A.C.M.
2023.
CD4+ T cell-mediated recognition of a conserved cholesterol-dependent cytolysin epitope generates broad antibacterial immunity.
Immunity
56
(5)
, pp. 1082-1097.
10.1016/j.immuni.2023.03.020
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Goncharov, Mikhail, Bagaev, Dmitry, Shcherbinin, Dmitrii, Zvyagin, Ivan, Bolotin, Dmitry, Thomas, Paul G., Minervina, Anastasia A., Pogorelyy, Mikhail V., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Nguyen, Thi H. O., Rowntree, Louise C., Clemens, E. Bridie, Kedzierska, Katherine, Dolton, Garry, Rius Rafael, Cristina ORCID: https://orcid.org/0000-0002-1896-1649, Sewell, Andrew ORCID: https://orcid.org/0000-0003-3194-3135, Samir, Jerome, Luciani, Fabio, Zornikova, Ksenia V., Khmelevskaya, Alexandra A., Sheetikov, Saveliy A., Efimov, Grigory A., Chudakov, Dmitry and Shugay, Mikhail
2022.
VDJdb in the pandemic era: a compendium of T cell receptors specific for SARS-CoV-2.
Nature Methods
19
(9)
, 1017–1019.
10.1038/s41592-022-01578-0
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Fielding, Ceri Alan ORCID: https://orcid.org/0000-0002-5817-3153, Sabberwal, Pragati, Williamson, James C., Greenwood, Edward J.D., Crozier, Thomas WM, Zelek, Wioleta, Seow, Jeffrey, Graham, Carl, Huettner, Isabella, Edgeworth, Jonathan D., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Morgan, Paul B. ORCID: https://orcid.org/0000-0003-4075-7676, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Eberl, Matthias ORCID: https://orcid.org/0000-0002-9390-5348, Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337, Merrick, Blair, Doores, Katie, Wilson, Sam J., Lehner, Paul J., Wang, Eddie C.Y. ORCID: https://orcid.org/0000-0002-2243-4964 and Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182
2022.
SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies.
eLife
11
10.7554/eLife.74489
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Pymm, Phillip, Tenzer, Stefan, Wee, Edmund, Weimershaus, Mirjana, Burgevin, Anne, Kollnberger, Simon, Gerstoft, Jan, Josephs, Tracy M., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934, Appay, Victor, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Fugger, Lars, Bell, John I., Schild, Hansjörg, van Endert, Peter, Harkiolaki, Maria and Iversen, Astrid K.N.
2022.
Epitope length variants balance protective immune responses and viral escape in HIV-1 infection.
Cell Reports
38
(9)
, 110449.
10.1016/j.celrep.2022.110449
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Campion, Suzanne L., Brenna, Elena, Thomson, Elaine, Fischer, Will, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Frahm, Nicole, McElrath, Juliana M., Cohen, Kristen W., Maenza, Janine R., Walsh, Stephen R., Baden, Lindsey R., Haynes, Barton F., Korber, Bette, Borrow, Persephone and McMichael, Andrew J.
2021.
Preexisting memory CD4+ T cells contribute to the primary response in an HIV-1 vaccine trial.
Journal of Clinical Investigation
131
(23)
, e150823.
10.1172/JCI150823
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Man, Stephen ORCID: https://orcid.org/0000-0001-9103-1686, Redman, James E. ORCID: https://orcid.org/0000-0001-5492-2869, Cross, Deborah L., Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Can, Ilona, Davies, Bethan, Hashimdeen, Shaikh Shimaz, Reid, Reiss, Llewellyn-Lacey, Sian, Miners, Kelly L., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Lissina, Anya, Brown, Paul E., Wooldridge, Linda, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and Rizkallah, Pierre J. ORCID: https://orcid.org/0000-0002-9290-0369
2021.
Synthetic peptides with inadvertent chemical modifications can activate potentially autoreactive T cells.
The Journal of Immunology
207
(4)
, pp. 1009-1017.
10.4049/jimmunol.2000756
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Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Knezevic, Lea, Dockree, Tamsin, McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly L., Llewellyn-Lacey, Sian, Rubina, Anzelika, Francis, Ore, Cole, David K. ORCID: https://orcid.org/0000-0003-0028-9396, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135, Bridgeman, John S., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, van den Berg, Hugo A. and Wooldridge, Linda
2021.
CD8 coreceptor-mediated focusing can reorder the agonist hierarchy of peptide ligands recognized via the T cell receptor.
Proceedings of the National Academy of Sciences
118
(29)
, e2019639118.
10.1073/pnas.2019639118
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Vlachava, Virginia-Maria ORCID: https://orcid.org/0000-0003-4233-7739, Murrell, Isa, Zhuang, Lihui, Aicheler, Rebecca J., Lim, Eleanor, Miners, Kelly L., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Suárez, Nicolás M., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Davison, Andrew J., Wilkinson, Gavin W.G., Wills, Mark R., Weekes, Michael P., Wang, Eddie C.Y. ORCID: https://orcid.org/0000-0002-2243-4964 and Stanton, Richard J. ORCID: https://orcid.org/0000-0002-6799-1182
2021.
Monoclonal antibodies targeting nonstructural viral antigens can activate ADCC against human cytomegalovirus.
Journal of Clinical Investigation
131
(4)
, e139296.
10.1172/JCI139296
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Hanna, Stephanie J., Codd, Amy S., Gea-Mallorqui, Ester, Scourfield, D. Oliver, Richter, Felix C., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Borsa, Mariana, Compeer, Ewoud B., Moon, Owen R., Galloway, Sarah A.E., Dimonte, Sandra, Capitani, Lorenzo, Shepherd, Freya R., Wilson, Joseph D., Uhl, Lion F. K., Ahern, David J., Almuttaqi, Hannah, Alonzi, Dominic S., Alrubayyi, Aljawharah, Alsaleh, Ghada, Bart, Valentina M. T., Batchelor, Vicky, Bayliss, Rebecca, Berthold, Dorothée L., Bezbradica, Jelena S., Bharuchq, Tehmina, Borrmann, Helene, Borsa, Mariana, Borst, Rowie, Brun, Juliane, Burnell, Stephanie, Capitani, Lorenzo, Cavounidis, Athena, Chapman, Lucy, Chauveau, Anne, Cifuentes, Liliana, Codd, Amy Susan, Compeer, Ewoud Bernardus, Coveney, Clarissa, Cross, Amy, Danielli, Sara, Davies, Luke C., Dendrou, Calliope A., Dimonte, Sandra, Peter Durairaj, Ruban Rex, Dustin, Lynn B., Dyer, Arthur, Fielding, Ceri, Fischer, Fabian, Gallimore, Awen ORCID: https://orcid.org/0000-0001-6675-7004, Galloway, Sarah, Gammage, Anís, Gea-Mallorquí, Ester, Godkin, Andrew, Hanna, Stephanie J., Heuberger, Cornelia, Hulin-Curtis, Sarah, Issa, Fadi, Jones, Emma, Jones, Ruth, Ladell, Kristin, Lauder, Sarah N., Liddiard, Kate, Ligoxygakis, Petros, Lu, Fangfang, MacLachlan, Bruce, Maleki-Toyserkani, Shayda, Mann, Elizabeth H., Marzeda, Anna M., Matthews, Reginald James, Mazet, Julie M., Milicic, Anita, Mitchell, Emma, Moon, Owen, Nguyen, Van Dien, O'Hanlon, Miriam, Eléonore Pavillet, Clara, Peppa, Dimitra, Pires, Ana, Pring, Eleanor, Quastel, Max, Reed, Sophie, Rehwinkel, Jan, Richmond, Niamh, Richter, Felix Clemens, Robinson, Alice J. B., Rodrigues, Patrícia R. S., Sabberwal, Pragati, Sami, Arvind, Peres, Raphael Sanches, Sattentau, Quentin, Schonfeldova, Barbora, Scourfield, David Oliver, Selvakumar, Tharini A., Shepherd, Freya R., Shorten, Cariad, Simon, Anna Katharina, Smith, Adrian L., Crespo, Alicia Teijeira, Tellier, Michael, Thornton, Emily, Uhl, Lion F. K., van Grinsven, Erinke, Wann, Angus K. T., Williams, Richard, Wilson, Joseph D., Zhou, Dingxi, Zhu, Zihan, Gallimore, Awen M. and Milicic, Anita
2021.
T cell phenotypes in COVID-19 - a living review.
Oxford Open Immunology
2
(1)
10.1093/oxfimm/iqaa007
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Galletti, Giovanni, De Simone, Gabriele, Mazza, Emilia M.C., Puccio, Simone, Mezzanotte, Claudia, Bi, Timothy M., Davydov, Alexey N., Metsger, Maria, Scamardella, Eloise, Alvisi, Giorgia, Paoli, Federica De, Zanon, Veronica, Scarpa, Alice, Camisa, Barbara, Colombo, Federico S., Anselmo, Achile, Peano, Clelia, Polletti, Sara, Mavilio, Domenico, Gattinoni, Luca, Boi, Shannon K., Youngblood, Benjamin A., Jones, Rhiannon E., Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467, Gostick, Emma, Llewellyn-Lacey, Sian, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Chudakov, Dmitriy M., Newell, Evan W., Casucci, Monica and Lugli, Enrico
2020.
Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans.
Nature Immunology
21
, pp. 1552-1562.
10.1038/s41590-020-0791-5
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Kasatskaya, Sofya A., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Egorov, Evgeniy S., Miners, Kelly L., Davydov, Alexey N., Metsger, Maria, Staroverov, Dmitry B., Matveyshina, Elena K., Shagina, Irina A., Mamedov, Ilgar Z., Izraelson, Mark, Shelyakin, Pavel V., Britanova, Olga V., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and Chudakov, Dmitriy M.
2020.
Functionally specialized human CD4+ T-cell subsets express physicochemically distinct TCRs.
eLife
9
, e57063.
10.7554/eLife.57063
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Ahmed, Raya, Miners, Kelly L., Lahoz-Beneytez, Julio, Jones, Rhiannon E., Roger, Laureline, Baboonian, Christina, Zhang, Yan, Wang, Eddie C. Y. ORCID: https://orcid.org/0000-0002-2243-4964, Hellerstein, Marc K., McCune, Joseph M., Baird, Duncan M. ORCID: https://orcid.org/0000-0001-8408-5467, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Macallan, Derek C., Asquith, Becca and Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938
2020.
CD57+ Memory T Cells Proliferate In Vivo.
Cell Reports
33
(11)
, 108501.
10.1016/j.celrep.2020.108501
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Narayanan, Gitanjali A., McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934, Meermeier, Erin W., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Swarbrick, Gwendolyn M., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Tran, Jessica G., Worley, Aneta H., Vogt, Todd, Wong, Emily B. and Lewinsohn, David M
2020.
The MAIT TCRβ chain contributes to discrimination of microbial ligand.
Immunology and Cell Biology
98
(9)
, pp. 770-781.
10.1111/imcb.12370
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Hanna, Stephanie J., Powell, Wendy E. ORCID: https://orcid.org/0000-0002-4670-1406, Long, Anna E., Robinson, Emma J. S., Davies, Joanne, Megson, Clare, Howell, Alexandra, Jones, Taz J., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Dayan, Colin M. ORCID: https://orcid.org/0000-0002-6557-3462, Williams, Alistair J. K., Gillespie, Kathleen M. and Wong, F. Susan ORCID: https://orcid.org/0000-0002-2812-8845
2020.
Slow progressors to type 1 diabetes lose islet autoantibodies over time, have few islet antigen-specific CD8+ T cells and exhibit a distinct CD95hi B cell phenotype.
Diabetologia
63
, pp. 1174-1185.
10.1007/s00125-020-05114-7
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Pearson, Frances E., Tullett, Kirsteen M., Leal-Rojas, Ingrid M., Haigh, Oscar L., Masterman, Kelly-Anne, Walpole, Carina, Bridgeman, John S., McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Miners, Kelly, Llewellyn-Lacey, Sian, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Tunger, Antje, Schmitz, Marc, Miles, John J, Lahoud, Mireille H and Radford, Kristen J
2020.
Human CLEC9A antibodies deliver Wilms' tumor 1 (WT1) antigen to CD141+ dendritic cells to activate naïve and memory WT1‐specific CD8+ T cells.
Clinical and Translational Immunology
9
10.1002/cti2.1141
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Edwards, Sarah C., Sutton, Caroline E., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Grant, Emma J., McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934, Roche, Fiona, Dash, Pradyot, Apiwattanakul, Nopporn, Awad, Walid, Miners, Kelly L., Lalor, Stephen J., Ribot, Julie C., Baik, Song, Moran, Barry, McGinley, Aoife, Pivorunas, Valerie, Dowding, Lori, Macoritto, Michael, Paez-Cortez, Jesus, Slavin, Anthony, Anderson, Graham, Silva-Santos, Bruno, Hokamp, Karsten, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Thomas, Paul G., McLoughlin, Rachel M. and Mills, Kingston H.G.
2020.
A population of proinflammatory T cells coexpresses αβ and γδ T cell receptors in mice and humans.
Journal of Experimental Medicine
217
(5)
, e20190834.
10.1084/jem.20190834
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Starke, Carly E., Vinton, Carol L., Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, McLaren, James E. ORCID: https://orcid.org/0000-0002-7021-5934, Ortiz, Alexandra M., Mudd, Joseph C., Flynn, Jacob K., Lai, Stephen H., Wu, Fan, Hirsch, Vanessa M., Darko, Samuel, Douek, Daniel C., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and Brenchley, Jason M.
2020.
SIV-specific CD8+ T cells are clonotypically distinct across lymphoid and mucosal tissues.
Journal of Clinical Investigation
130
(2)
, pp. 789-798.
10.1172/JCI129161
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Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Ekeruche, Julia, Miles, John James, Edwards, Emily ORCID: https://orcid.org/0000-0002-0240-4370, Dolton, Garry Michael, Williams, Tamsin, Schauenburg, Andrea J. A., Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Lauder, Sarah Nicol, Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Burrows, Scott R., Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 and Wooldridge, Linda
2011.
Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining.
The Journal of Immunology
187
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10.4049/jimmunol.1003941
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Kreutzman, A., Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Koechel, C., Gostick, Emma, Ekblom, M., Stenke, L., Melo, T., Einsele, H., Porkka, K., Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Mustjoki, S. and Seggewiss, R.
2011.
Expansion of highly differentiated CD8+ T-cells or NK-cells in patients treated with dasatinib is associated with cytomegalovirus reactivation.
Leukemia
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10.1038/leu.2011.135
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Hindley, James Philip, Ferreira, Cristina, Jones, Emma, Lauder, Sarah Nicol, Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Wynn, Katherine, Betts, Gareth James, Singh, Yogesh, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Dyson, Julian and Gallimore, Awen Myfanwy ORCID: https://orcid.org/0000-0001-6675-7004
2011.
Analysis of the T-cell receptor repertoires of tumor-infiltrating conventional and regulatory T cells reveals no evidence for conversion in carcinogen-induced tumors.
Cancer Research
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10.1158/0008-5472.CAN-10-1797
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van Bockel, David J., Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Munier, Mee Ling, Venturi, Vanessa, Asher, Tedi E., Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Greenaway, Hui Yee, Zaunders, John, Douek, Daniel C., Cooper, David A., Davenport, Miles P. and Kelleher, Anthony D.
2010.
Persistent survival of prevalent clonotypes within an immunodominant HIV gag-specific CD8+ T cell response.
The Journal of Immunology
186
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, pp. 359-371.
10.4049/jimmunol.1001807
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Jones, Morgan, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Wynn, Katherine, Stacey, Maria A., Quigley, Maire F., Gostick, Emma, Price, David ORCID: https://orcid.org/0000-0001-9416-2737 and Humphreys, Ian R. ORCID: https://orcid.org/0000-0002-9512-5337
2010.
IL-10 restricts memory T cell inflation during cytomegalovirus infection.
The Journal of Immunology
185
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10.4049/jimmunol.1001535
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Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Edwards, Emily ORCID: https://orcid.org/0000-0002-0240-4370, Wynn, Katherine, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Miles, John James, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Ekeruche, Julia, Gostick, Emma, Adams, Katherine J., Skowera, Ania, Peakman, Mark, Wooldridge, Linda, Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135
2010.
Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition.
The Journal of Immunology
185
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10.4049/jimmunol.1000629
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Wooldridge, Linda, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Lissina, Anna, Edwards, Emily ORCID: https://orcid.org/0000-0002-0240-4370, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Ekeruche, Julia, Hewitt, R. E., Laugel, Bruno Frederic, Gostick, Emma, Cole, David ORCID: https://orcid.org/0000-0003-0028-9396, Debets, R., Berrevoets, C., Miles, John James, Burrows, S. R., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135
2010.
MHC Class I molecules with superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs.
Journal of Immunology
184
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10.4049/jimmunol.0902398
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Van Tendeloo, V. F., Van de Velde, A., Van Driessche, A., Cools, N., Anguille, S., Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Gostick, Emma, Vermeulen, K., Pieters, K., Nijs, G., Stein, B., Smits, E. L., Schroyens, W. A., Gadisseur, A. P., Vrelust, I., Jorens, P. G., Goossens, H., de Vries, I. J., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737, Oji, Y., Oka, Y., Sugiyama, H. and Berneman, Z. N.
2010.
Induction of complete and molecular remissions in acute myeloid leukemia by Wilms' tumor 1 antigen-targeted dendritic cell vaccination.
Proceedings of the National Academy of Sciences of the United States of America
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10.1073/pnas.1008051107
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Harris, L. D., Klatt, N. R., Vinton, C., Briant, J. A., Tabb, B., Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Lifson, Jeffrey, Estes, J. D., Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Hirsch, V. M. and Brenchley, J. M.
2010.
Mechanisms underlying γδ T-cell subset perturbations in SIV-infected Asian rhesus macaques.
Blood
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10.1182/blood-2010-05-283549
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Subramanya, Sandesh, Armant, Myriam, Salkowitz, Janelle R., Nyakeriga, Alice M., Haridas, Viraga, Hasan, Maroof, Bansal, Anju, Goepfert, Paul A., Wynn, Katherine, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, N, Manjunath, Kan-Mitchell, June and Shankar, Premlata
2010.
Enhanced induction of HIV-specific Cytotoxic T Lymphocytes by Dendritic cell-targeted delivery of SOCS-1 siRNA.
Molecular Therapy
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10.1038/mt.2010.148
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Melenhorst, J. Joseph, Scheinberg, Phillip, Chattopadhyay, Pratip K., Gostick, Emma, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Roederer, Mario, Hensel, Nancy F., Douek, Daniel C., Barrett, A. John and Price, David ORCID: https://orcid.org/0000-0001-9416-2737
2009.
High avidity myeloid leukemia-associated antigen-specific CD8+ T cells preferentially reside in the bone marrow.
Blood
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10.1182/blood-2008-04-151969
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Lissina, Anna, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Skowera, Ania, Clement, Mathew ORCID: https://orcid.org/0000-0002-9280-5281, Edwards, Emily ORCID: https://orcid.org/0000-0002-0240-4370, Seggewiss, Ruth, van den Berg, Hugo A., Gostick, Emma, Gallagher, Kathleen, Jones, Emma, Melenhorst, J. Joseph, Godkin, Andrew James ORCID: https://orcid.org/0000-0002-1910-7567, Peakman, Mark, Price, David ORCID: https://orcid.org/0000-0001-9416-2737, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 and Wooldridge, Linda
2009.
Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers.
Journal of Immunological Methods
340
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10.1016/j.jim.2008.09.014
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Venturi, Vanessa, Chin, Hui Yee, Tedi, E. Asher, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Scheinberg, Phillip, Bornstein, Ethan, van Bockel, David, Kelleher, Anthony D., Douek, Daniel C., Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737 and Davenport, Miles P.
2008.
TCR β-Chain sharing in human CD8+ T cell responses to cytomegalovirus and EBV.
Journal of Immunology
181
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10.4049/jimmunol.181.11.7853
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Chattopadhyay, Pratip K., Melenhorst, J. Joseph, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Gostick, Emma, Scheinberg, Phillip, Barrett, A. John, Wooldridge, Linda, Roederer, Mario, Sewell, Andrew K. ORCID: https://orcid.org/0000-0003-3194-3135 and Price, David A. ORCID: https://orcid.org/0000-0001-9416-2737
2008.
Techniques to improve the direct ex vivo detection of low frequency antigen-specific CD8+T cells with peptide-major histocompatibility complex class I tetramers.
Cytometry Part A
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10.1002/cyto.a.20642
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Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Hellerstein, M. K., Cesar, D., Busch, R., Boban, D. and McCune, J. M.
2008.
Central memory CD8+ T cells appear to have a shorter lifespan and reduced abundance as a function of HIV disease progression.
The Journal of Immunology
180
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10.4049/jimmunol.180.12.7907
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Ladell, Kristin ORCID: https://orcid.org/0000-0002-9856-2938, Dorner, Marcus, Zauner, Ludwig, Berger, Christoph, Zucol, Franziska, Bernasconi, Michele, Niggli, Felix K., Speck, Roberto F. and Nadal, David
2007.
Immune activation suppresses initiation of lytic Epstein-Barr virus infection.
Cellular Microbiology
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10.1111/j.1462-5822.2007.00937.x
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Giger, Bettina, Bonanomi, Athos, Odermatt, Bernhard, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Speck, Roberto F, Kojic, Dejan, Berger, Christoph, Niggli, Felix K and Nadal, David
2004.
Human tonsillar tissue block cultures differ from autologous tonsillar cell suspension cultures in lymphocyte subset activation and cytokine gene expression.
Journal of Immunological Methods
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10.1016/j.jim.2004.04.015
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Keyser, Johanna, Schultz, Jan, Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Elzaouk, Lina, Heinzerling, Lucie, Pavlovic, Jovan and Moelling, Karin
2004.
IP-10-encoding plasmid DNA therapy exhibits anti-tumor and anti-metastatic efficiency.
Experimental Dermatology
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10.1111/j.0906-6705.2004.00191.x
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Ladell, Kristin Ingrid ORCID: https://orcid.org/0000-0002-9856-2938, Heinrich, J., Schweneker, M. and Moelling, K.
2003.
A combination of plasmid DNAs encoding murine fetal liver kinase 1 extracellular domain, murine interleukin-12, and murine interferon-y inducible protein-10 leads to tumor regression and survival in melanoma-bearing mice.
Journal of Molecular Medicine
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10.1007/s00109-003-0425-z
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