ORCA
Online Research @ Cardiff
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Koch, Elise, Smart, Sophie  ORCID: https://orcid.org/0000-0002-6709-5425, Einarsson, Guðmundur, Kämpe, Anders, Jonsson, Lina, Alver, Maris, Iveson, Matthew, Göteson, Andreas, Pardiñas, Antonio F. ORCID: https://orcid.org/0000-0001-6845-7590, Sønderby, Ida E, O'Connell, Kevin S., Li, Qingqin, Lu, Yi, Stefánsson, Hreinn, Stefánsson, Kári, Whalley, Heather, Landén, Mikael, O'Donovan, Michael C. ORCID: https://orcid.org/0000-0001-7073-2379, Smerud, Knut, Dawson, Gerard R., Werge, Thomas, Buil, Alfonso, Reif, Andreas, Milani, Lili, Molden, Espen, Fabbri, Chiara, Serretti, Alessandro, Walters, James ORCID: https://orcid.org/0000-0002-6980-4053, Lewis, Cathryn M. and Andreassen, Ole A.
2025.
Recommendations for defining treatment outcomes in major psychiatric disorders using real-world data.
The Lancet Psychiatry
12
(6)
, pp. 457-468.
10.1016/S2215-0366(25)00061-6
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Dempster, Emma, Wong, Chloe, Burrage, Joe, Hannon, Eilis, Quattrone, Diego, Trotta, Giulia, Rodriguez, Victoria, Alameda, Luis, Spinazzola, Edouardo, Tripoli, Giada, Austin-Zimmerman, Isabelle, Li, Zhikun, Gayer-Anderson, Charlotte, Freeman, Tom, Johnson, Emma, Jongsma, Hannah, Stilo, Simona, La Cascia, Caterina, Ferraro, Laura, La Barbera, Daniele, Lasalvia, Antonio, Tosato, Sarah, Tarricone, Ilaria, D'Andrea, Giuseppe, Galatolo, Michela, Tortelli, Andrea, Pompili, Maurizio, Selten, Jean-Paul, de Haan, Lieuwe, Rossi Menezes, Paulo, Del Ben, Cristina M., Santos, Jose Luis, Arrojo, Manuel, Bobes, Julio, Sanjuan, Miguel, Arango, Celso, Jones, Peter B., Breen, Gerome, Mondelli, Valeria, Dazzan, Paola, Iyegbe, Conrad, Vassos, Evangelos, Morgan, Craig, Mukherjee, Diptendu, van Os, Jim, Rutten, Bart, O'Donovan, Michael C. ORCID: https://orcid.org/0000-0001-7073-2379, Sham, Pak, Mill, Jonathan, Murray, Robin and Di Forti, Marta
2025.
Methylomic signature of current cannabis use in two first-episode psychosis cohorts.
Molecular Psychiatry
30
, pp. 1277-1286.
10.1038/s41380-024-02689-0
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O'Connell, Kevin S., Koromina, Maria, van der Veen, Tracey, Boltz, Toni, David, Friederike S., Yang, Jessica Mei Kay, Lin, Keng-Han, Wang, Xin, Coleman, Jonathan R. I., Mitchell, Brittany L., McGrouther, Caroline C., Rangan, Aaditya V., Lind, Penelope A., Koch, Elise, Harder, Arvid, Parker, Nadine, Bendl, Jaroslav, Adorjan, Kristina, Agerbo, Esben, Albani, Diego, Alemany, Silvia, Alliey-Rodriguez, Ney, Als, Thomas D., Andlauer, Till F. M., Antoniou, Anastasia, Ask, Helga, Bass, Nicholas, Bauer, Michael, Beins, Eva C., Bigdeli, Tim B., Pedersen, Carsten Bøcker, Boks, Marco P., Børte, Sigrid, Bosch, Rosa, Brum, Murielle, Brumpton, Ben M., Brunkhorst-Kanaan, Nathalie, Budde, Monika, Bybjerg-Grauholm, Jonas, Byerley, William, Cabana-Domínguez, Judit, Cairns, Murray J., Carpiniello, Bernardo, Casas, Miquel, Cervantes, Pablo, Chatzinakos, Chris, Chen, Hsi-Chung, Clarence, Tereza, Clarke, Toni-Kim, Claus, Isabelle, Coombes, Brandon, Corfield, Elizabeth C., Cruceanu, Cristiana, Cuellar-Barboza, Alfredo, Czerski, Piotr M., Dafnas, Konstantinos, Dale, Anders M., Dalkner, Nina, Degenhardt, Franziska, DePaulo, J. Raymond, Djurovic, Srdjan, Drange, Ole Kristian, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Fanous, Ayman H., Fellendorf, Frederike T., Ferrier, I. Nicol, Forty, Elizabeth, Frank, Josef, Frei, Oleksandr, Freimer, Nelson B., Fullard, John F., Garnham, Julie, Gizer, Ian R., Gordon, Scott D., Gordon-Smith, Katherine, Greenwood, Tiffany A., Grove, Jakob, Guzman-Parra, José, Ha, Tae Hyon, Hahn, Tim, Haraldsson, Magnus, Hautzinger, Martin, Havdahl, Alexandra, Heilbronner, Urs, Hellgren, Dennis, Herms, Stefan, Hickie, Ian B., Hoffmann, Per, Holmans, Peter A. ORCID: https://orcid.org/0000-0003-0870-9412, Huang, Ming-Chyi, Ikeda, Masashi, Jamain, Stéphane, Johnson, Jessica S., Jonsson, Lina, Kalman, Janos L., Kamatani, Yoichiro, Kennedy, James L., Kim, Euitae, Kim, Jaeyoung, Kittel-Schneider, Sarah, Knowles, James A., Kogevinas, Manolis, Kranz, Thorsten M., Krebs, Kristi, Kushner, Steven A., Lavebratt, Catharina, Lawrence, Jacob, Leber, Markus, Lee, Heon-Jeong, Liao, Calwing, Lucae, Susanne, Lundberg, Martin, MacIntyre, Donald J., Maier, Wolfgang, Maihofer, Adam X., Malaspina, Dolores, Manchia, Mirko, Maratou, Eirini, Martinsson, Lina, Mattheisen, Manuel, McGregor, Nathaniel W., McInnis, Melvin G., McKay, James D., Medeiros, Helena, Meyer-Lindenberg, Andreas, Millischer, Vincent, Morris, Derek W., Moutsatsou, Paraskevi, Mühleisen, Thomas W., O'Donovan, Claire, Olsen, Catherine M., Panagiotaropoulou, Georgia, Papiol, Sergi, Pardinas, Antonio F. ORCID: https://orcid.org/0000-0001-6845-7590, Park, Hye Youn, Perry, Amy, Pfennig, Andrea, Pisanu, Claudia, Potash, James B., Quested, Digby, Rapaport, Mark H., Regeer, Eline J., Rice, John P., Rivera, Margarita, Schulte, Eva C., Senner, Fanny, Shadrin, Alexey, Shilling, Paul D., Sigurdsson, Engilbert, Sindermann, Lisa, Sirignano, Lea, Siskind, Dan, Slaney, Claire, Sloofman, Laura G., Smeland, Olav B., Smith, Daniel J., Sobell, Janet L., Soler Artigas, Maria, Stein, Dan J., Stein, Frederike, Su, Mei-Hsin, Sung, Heejong, Swiatkowska, Beata, Terao, Chikashi, Tesfaye, Markos, Tesli, Martin, Thorgeirsson, Thorgeir E., Thorp, Jackson G., Toma, Claudio, Tondo, Leonardo, Tooney, Paul A., Tsai, Shih-Jen, Tsermpini, Evangelia Eirini, Vawter, Marquis P., Vedder, Helmut, Vreeker, Annabel, Walters, James T. R., Winsvold, Bendik S., Witt, Stephanie H., Won, Hong-Hee, Ye, Robert, Young, Allan H., Zandi, Peter P., Zillich, Lea, Lee, Byung-Chul, Kim, Ji-Woong, Lee, Young Kee, Kang, Joon Ho, Cheon, Myeong Jae, Kim, Dong Jun, Aslan, Mihaela, Harvey, Philip D., Huang, Grant D., Adolfsson, Rolf, Alda, Martin, Alfredsson, Lars, Backlund, Lena, Baune, Bernhard T., Bellivier, Frank, Bengesser, Susanne, Berrettini, Wade H., Biernacka, Joanna M., Boehnke, Michael, Børglum, Anders D., Breen, Gerome, Carr, Vaughan J., Catts, Stanley, Cichon, Sven, Corvin, Aiden, Craddock, Nicholas, Dannlowski, Udo, Dikeos, Dimitris, Etain, Bruno, Ferentinos, Panagiotis, Frye, Mark, Fullerton, Janice M., Gawlik, Micha, Gershon, Elliot S., Goes, Fernando S., Green, Melissa J., Grigoroiu-Serbanescu, Maria, Hauser, Joanna, Henskens, Frans A., Hjerling-Leffler, Jens, Hougaard, David M., Hveem, Kristian, Iwata, Nakao, Jones, Ian, Jones, Lisa A., Kahn, René S., Kelsoe, John R., Kircher, Tilo, Kirov, George, Kuo, Po-Hsiu, Landén, Mikael, Leboyer, Marion, Li, Qingqin S., Lissowska, Jolanta, Lochner, Christine, Loughland, Carmel, Luykx, Jurjen J., Martin, Nicholas G., Mathews, Carol A., Mayoral, Fermin, McElroy, Susan L., McIntosh, Andrew M., McMahon, Francis J., Medland, Sarah E., Melle, Ingrid, Milani, Lili, Mitchell, Philip B., Morken, Gunnar, Mors, Ole, Mortensen, Preben Bo, Müller-Myhsok, Bertram, Myers, Richard M., Myung, Woojae, Neale, Benjamin M., Nievergelt, Caroline M., Nordentoft, Merete, Nöthen, Markus M., Nurnberger, John I., O'Donovan, Michael C. ORCID: https://orcid.org/0000-0001-7073-2379, Oedegaard, Ketil J., Olsson, Tomas, Owen, Michael J., Paciga, Sara A., Pantelis, Christos, Pato, Carlos N., Pato, Michele T., Patrinos, George P., Pawlak, Joanna M., Ramos-Quiroga, Josep Antoni, Reif, Andreas, Reininghaus, Eva Z., Ribasés, Marta, Rietschel, Marcella, Ripke, Stephan, Rouleau, Guy A., Roussos, Panos, Saito, Takeo, Schall, Ulrich, Schalling, Martin, Schofield, Peter R., Schulze, Thomas G., Scott, Laura J., Scott, Rodney J., Serretti, Alessandro, Smoller, Jordan W., Squassina, Alessio, Stahl, Eli A., Stefansson, Hreinn, Stefansson, Kari, Stordal, Eystein, Streit, Fabian, Sullivan, Patrick F., Turecki, Gustavo, Vaaler, Arne E., Vieta, Eduard, Vincent, John B., Waldman, Irwin D., Weickert, Cynthia S., Weickert, Thomas W., Werge, Thomas, Whiteman, David C., Zwart, John-Anker, Edenberg, Howard J., McQuillin, Andrew, Forstner, Andreas J., Mullins, Niamh, Di Florio, Arianna ORCID: https://orcid.org/0000-0003-0338-2748, Ophoff, Roel A., Andreassen, Ole A., van der Veen, Tracey and Siskind, Dan
2025.
Genomics yields biological and phenotypic insights into bipolar disorder.
Nature
639
, pp. 968-975.
10.1038/s41586-024-08468-9
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Schipper, Marijn, Leeuw, Christiaan, Maciel, Bernardo, Wightman, Hubers, Boomsma, Dorret, O’Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379 and Posthuma, Danielle
2025.
Prioritizing effector genes at trait-associated loci using multimodal evidence.
Nature Genetics
57
, pp. 323-333.
10.1038/s41588-025-02084-7
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Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael C. ORCID: https://orcid.org/0000-0001-7073-2379
2025.
The genetics of cognition in schizophrenia.
Genomic Psychiatry
1
(1)
, pp. 28-35.
10.61373/gp024i.0040
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Panagiotaropoulou, Georgia, Hellberg, Kajsa-Lotta Georgii, Coleman, Jonathan R. I., Seok, Darsol, Kalman, Janos, Bipolar Disorder Working Group of the Psychiatric Genomics Conso, Major Depressive Disorder Working Group of the Psychiatric Genom, iPSYCH Study Consortium, Mitchell, Philip B., Schofield, Peter R., Forstner, Andreas J., Bauer, Michael, Scott, Laura J., Pato, Carlos N., Pato, Michele T., Li, Qingqin S., Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950, Landén, Mikael, Jonsson, Lina, Müller-Myhsok, Bertram, Smoller, Jordan W., Binder, Elisabeth B., Brückl, Tanja M., Czamara, Darina, Van der Auwera, Sandra, Grabe, Hans J., Homuth, Georg, Schmidt, Carsten O., Potash, James B., DePaulo, J.Raymond, Goes, Fernando S., MacKinnon, Dean F., Mondimore, Francis M., Weissman, Myrna M., Shi, Jianxin, Frye, Mark A., Biernacka, Joanna M., Reif, Andreas, Witt, Stephanie H., Kahn, René R., Boks, Marco M., Owen, Michael J. ORCID: https://orcid.org/0000-0003-4798-0862, Gordon-Smith, Katherine, Mitchell, Brittany L., Martin, Nicholas G., Medland, Sarah E., Jones, Lisa., Knowles, James A., Levinson, Douglas F., O'Donovan, Michael C. ORCID: https://orcid.org/0000-0001-7073-2379, Lewis, Cathryn M., Breen, Gerome, Werge, Thomas, Schork, Andrew J., Ophoff, Roel A., Ripke, Stephan and Olde Loohuis, Loes
2025.
Identifying genetic differences between bipolar disorder and major depression through multiple genome-wide association analyses.
The British Journal of Psychiatry
10.1192/bjp.2024.125
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Owen, Michael ORCID: https://orcid.org/0000-0003-4798-0862, Bray, Nicholas ORCID: https://orcid.org/0000-0002-4357-574X, Walters, James ORCID: https://orcid.org/0000-0002-6980-4053 and O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379
2025.
Genomics of major mental illness.
Nature Reviews Genetics
Item availability restricted. |
 
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Agrawal, Arpana, Bulik, Cynthia M., Abebe, Dawit Shawel, Andreassen, Ole A., Atkinson, Elizabeth G., Choi, Karmel W., Corvin, Aiden, Davies, Helena L., Davies, Lea K., Docherty, Anna R., Edenberg, Howard J., Franke, Barbara, Gelernter, Joel, Giusti - Rodriquez, Paola, Hettema, John M., Hjerling - Leffler, Jens, Huang, Hailiang, Johnson, Emma C., Lewis, Cathryn M., Lu, Yi, Lynall, Mary-Ellen, Martin, Joanna ORCID: https://orcid.org/0000-0002-8911-3479, McIntosh, Andrew M., Montalvo-Ortiz, Janitza L., Mullins, Niamh, Nievergelt, Caroline M., O'Connell, Kevin S., O'Donovan, Michael C. ORCID: https://orcid.org/0000-0001-7073-2379, Okewole, Adeniran, Peterson, Roseann E., Posthuma, Danielle, Sebat, Jonathan, Smoller, Jordan W., Sud, Reeteka, Viswanath, Biju, Walters, James T.R., Won, Hyejung, Wray, Naomi R. and Sullivan, Patrick F.
2025.
The Psychiatric Genomics Consortium: Discoveries and directions.
The Lancet Psychiatry
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Rodriguez, Victoria, Alameda, Luis, Aas, Monica, Gayer-Anderson, Charlotte, Trotta, Giulia, Spinazzola, Edoardo, Quattrone, Diego, Tripoli, Giada, Jongsma, Hannah E., Stilo, Simona, La Cascia, Caterina, Ferraro, Laura, La Barbera, Daniele, Lasalvia, Antonio, Tosato, Sarah, Tarricone, Ilaria, Bonora, Elena, Jamain, Stéphane, Selten, Jean-Paul, Velthorst, Eva, de Haan, Lieuwe, Llorca, Pierre-Michel, Arrojo, Manuel, Bobes, Julio, Bernardo, Miguel, Arango, Celso, Kirkbride, James, Jones, Peter B., Rutten, Bart P, Richards, Alexander, Sham, Pak C., O’Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379, Van Os, Jim, Morgan, Craig, Di Forti, Marta, Murray, Robin M. and Vassos, Evangelos
2024.
Polygenic and polyenvironment interplay in schizophrenia-spectrum disorder and affective psychosis; the EUGEI first episode study.
Schizophrenia Bulletin: The Journal of Psychoses and Related Disorders
, sbae207.
10.1093/schbul/sbae207
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Austin-Zimmerman, Isabelle, Spinazzola, Edoardo, Quattrone, Diego, Wu-Choi, Beatrice, Trotta, Giulia, Li, Zhikun, Johnson, Emma, Richards, Alexander L., Freeman, Tom P., Tripoli, Giada, Gayer-Anderson, Charlotte, Rodriguez, Victoria, Jongsma, Hannah E., Ferraro, Laura, La Cascia, Caterina, Tosato, Sarah, Tarricone, Ilaria, Berardi, Domenico, Bonora, Elena, Seri, Marco, D'Andrea, Giuseppe, Szöke, Andrei, Arango, Celso, Bobes, Julio, Sanjuán, Julio, Santos, Jose Luis, Arrojo, Manuel, Velthorst, Eva, Bernardo, Miguel, Del-Ben, Cristina Marta, Rossi Menezes, Paulo, Selten, Jean-Paul, Jones, Peter B., Kirkbride, James B., Rutten, Bart P. F., Tortelli, Andrea, Llorca, Pierre-Michel, de Haan, Lieuwe, Stilo, Simona, La Barbera, Daniele, Lasalvia, Antonio, Schurnhoff, Franck, Pignon, Baptiste, van Os, Jim, Lynskey, Michael, Morgan, Craig, O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379, Lewis, Cathryn M., Sham, Pak C., Murray, Robin M., Vassos, Evangelos and Di Forti, Marta
2024.
The impact of schizophrenia genetic load and heavy cannabis use on the risk of psychotic disorder in the EU-GEI case-control and UK Biobank studies.
Psychological Medicine
10.1017/S0033291724002058
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Koch, Elise, Pardinas, Antonio F. ORCID: https://orcid.org/0000-0001-6845-7590, O’Connell, Kevin S., Selvaggi, Pierluigi, Camacho Collados, Jose ORCID: https://orcid.org/0000-0003-1618-7239, Babic, Aleksandar, Marshall, Serena E., Van der Eycken, Erik, Angulo, Cecilia, Lu, Yi, Sullivan, Patrick F., Dale, Anders M., Molden, Espen, Posthuma, Danielle, White, Nathan, Schubert, Alexander, Djurovic, Srdjan, Heimer, Hakon, Stefánsson, Hreinn, Stefánsson, Kári, Werge, Thomas, Sønderby, Ida, O’Donovan, Michael C. ORCID: https://orcid.org/0000-0001-7073-2379, Walters, James T.R. ORCID: https://orcid.org/0000-0002-6980-4053, Milani, Lili and Andreassen, Ole A.
2024.
How real-world data can facilitate the development of precision medicine treatment in psychiatry.
Biological Psychiatry
96
(7)
, pp. 543-551.
10.1016/j.biopsych.2024.01.001
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Cameron, Darren, Vihn, Ngoc-Nga, Prapaiwongs, Parinda, Perry, Elizabeth A., Walters, James T. R. ORCID: https://orcid.org/0000-0002-6980-4053, Li, Meng ORCID: https://orcid.org/0000-0002-4803-4643, O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379 and Bray, Nicholas ORCID: https://orcid.org/0000-0002-4357-574X
2024.
Genetic implication of prenatal GABAergic and cholinergic neuron development in susceptibility to schizophrenia.
Schizophrenia Bulletin Open
50
(5)
, pp. 1171-1184.
10.1093/schbul/sbae083
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González-Peñas, Javier, Alloza, Clara, Brouwer, Rachel, Díaz-Caneja, Covadonga M, Costas, Javier, González-Lois, Noemi, Gallego, Ana Guil, de Hoyos, Lucia, Gurriarán, Xaquín, Andreu-Bernabeu, Álvaro, Romero-García, Rafael, Fananas, Lourdes, Bobes, Julio, Gonzales Pinto, Ana, Crespo-Facorro, Benedicto, Martorell, Lourdes, Arrojo, Manuel, Vilella, Elisabet, Guitiérrez-Zotes, Alfonso, Perez-Rando, Marta, Moltó, María Dolores, CIBERSAM group, Buimer, Elizabeth, van Haren, Neeltje, Cahn, Wiepke, O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379, Kahn, Rene, Arango, Celso, Hulshoff Pol, Hilleke, Janssen, Joost and Schnack, Hugo
2024.
Accelerated cortical thinning in schizophrenia is associated with rare and common predisposing variation to schizophrenia and neurodevelopmental disorders.
Biological Psychiatry
96
(5)
, pp. 376-389.
10.1016/j.biopsych.2024.03.011
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Frei, Oleksandr, Hindley, Guy, Shadrin, Alexey, van der Meer, Dennis, Akdeniz, Bayram, Hagen, Espen, Cheng, Weiqiu, O'Connell, Kevin, Bahrami, Shahram, Parker, Nadine, Smeland, Olav, Holland, Dominic, Schizophrenia Working Group of the Psychiatric Genomics Consorti, de Leeuw, Christiaan, Posthuma, Danielle, Andreassen, Ole, Dale, Anders and O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379
2024.
Improved functional mapping of complex trait heritability with GSA-MiXeR implicates biologically specific gene sets.
Nature Genetics
56
, pp. 1310-1318.
10.1038/s41588-024-01771-1
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D'Andrea, Giuseppe, Quattrone, Diego, Malone, Kathryn, Tripoli, Giada, Trotta, Giulia, Spinazzola, Edoardo, Gayer-Anderson, Charlotte, Jongsma, Hannah, Sideli, Lucia, Stilo, Simona, La Cascia, Caterina, Ferraro, Laura, Lasalvia, Antonio, Tosato, Sarah, Tortelli, Andrea, Velthorst, Eva, de Haan, Lieuwe, Llorca, Pierre-Michel, Menezes, Paulo Rossi, Santos, Jose Luis, Arrojo, Manuel, Bobes, Julio, Sanjuan, Julio, Bernado, Miguel, Arango, Celso, Kirkbride, James, Jones, Peter, Rutten, Bart, Van Os, Jim, Selten, Jean-Paul, Vassos, Evangelos, Schurhoff, Franck, Szoke, Andrei, Pignon, Baptiste, O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379, Richards, Alexander, Morgan, Craig, Di Forti, Marta, Tarricone, Ilaria and Murray, Robin
2024.
Variation of subclinical psychosis across 16 sites in Europe and Brazil: findings from the multi-national EU-GEI study.
Psychological Medicine
54
(8)
, pp. 1810-1823.
10.1017/S0033291723003781
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Clifton, Nicholas E. ORCID: https://orcid.org/0000-0003-2597-5253, Lin, Julie Qiaojin, Holt, Christine E., O’Donovan, Michael C. ORCID: https://orcid.org/0000-0001-7073-2379 and Mill, Jonathan
2024.
Enrichment of the local synaptic translatome for genetic risk associated with schizophrenia and autism spectrum disorder.
Biological Psychiatry
95
(9)
, pp. 888-895.
10.1016/j.biopsych.2023.12.006
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van der Meer, Dennis, Cheng, Weiqiu, Rokicki, Jaroslav, Fernandez-Cabello, Sara, Shadrin, Alexey, Smeland, Olav B., Ehrhart, Friederike, Gülöksüz, Sinan, Pries, Lotta-Katrin, Lin, Bochao, Rutten, Bart P. F., van Os, Jim, O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379, Richards, Alexander L., Steen, Nils Eiel, Djurovic, Srdjan, Westlye, Lars T., Andreassen, Ole A., Kaufmann, Tobias, Aguilar, Eduardo J., Akdede, Berna, Alptekin, Köksal, Altinyazar, Vesile, Amoretti, Silvia, Andric-Petrovic, Sanja, Arango, Celso, Arrojo, Manuel, Atbasoglu, Cem, Bernardo, Miguel, Binbay, Tolga, Bobes, Julio, Cankurtaran, Eylem ahin, Carracedo, Angel, Cihan, Burçin, Delespaul, Philippe, García-Portilla, Maria Paz, González-Peñas, Javier, Guloksuz, Sinan, Gümüs-Akay, Güvem, Jiménez-López, Estela, Ulusoy Kaymak, Semra, Kenis, Gunter, Lin, Bochao D., López, Gonzalo, Luykx, Jurjen J., Maric, Nadja P., Mezquida, Gisela, Mihaljevic, Marina M., Mirjanic, Tijana, Parellada, Mara, Pries, Katrin, Rivero, Olga, Rutten, Bart P. F., Saiz, Pilar A., Can Saka, Meram, Sanjuan, Julio, Luis Santos, José, Soygür, Haldun, Üçok, Alp, Ulas, Halis, van Os, Jim, Yalinçetin, Berna, Alizadeh, Behrooz Z., van Amelsvoort, Therese, Cahn, Wiepke, de Haan, Lieuwe, Schirmbeck, Frederike, van Os, Jim and Veling, Wim
2024.
Clustering schizophrenia genes by their temporal expression patterns aids functional interpretation.
Schizophrenia Bulletin: The Journal of Psychoses and Related Disorders
50
(2)
, pp. 327-338.
10.1093/schbul/sbad140
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Kappel, Djenifer, Rees, Elliott ORCID: https://orcid.org/0000-0002-6168-9222, Fenner, Eilidh, King, Adrian, Jansen, John, Helthius, Marinka, Owen, Michael ORCID: https://orcid.org/0000-0003-4798-0862, O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379, Walters, James ORCID: https://orcid.org/0000-0002-6980-4053 and Pardinas, Antonio ORCID: https://orcid.org/0000-0001-6845-7590
2024.
Rare variants in pharmacogenes influence clozapine metabolism in individuals with schizophrenia.
European Neuropsychopharmacology
80
, pp. 47-54.
10.1016/j.euroneuro.2023.12.007
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Wang, Sheng, Wang, Belinda, Drury, Vanessa, Drake, Sam, Sun, Nawei, Alkhairo, Hasan, Arbelaez, Juan, Duhn, Clif, Tourette International Collaborative Genetics (TIC Genetics), Bal, Vanessa, Langley, Kate ORCID: https://orcid.org/0000-0002-2033-2657, Martin, Joanna ORCID: https://orcid.org/0000-0002-8911-3479, Hoekstra, Pieter, Dietrich, Andrea, Xing, Jinchuan, Heiman, Gary, Tischfield, Jay, Fernandez, Thomas, Owen, Michael ORCID: https://orcid.org/0000-0003-4798-0862, O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379, Thapar, Anita ORCID: https://orcid.org/0000-0002-3689-737X, State, Matthew and Willsey, Jeremy
2023.
Rare X-linked variants carry predominantly male risk in Autism, Tourette Syndrome, and ADHD.
Nature Communications
14
, 8077.
10.1038/s41467-023-43776-0
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Spinazzola, Edoardo, Quattrone, Diego, Rodriguez, Victoria, Trotta, Giulia, Alameda, Luis, Tripoli, Giada, Gayer-Anderson, Charlotte, Freeman, Tom P., Johnson, Emma C., Jongsma, Hannah E., Stilo, Simona, La Cascia, Caterina, Ferraro, Laura, La Barbera, Daniele, Lasalvia, Antonio, Tosato, Sarah, Tarricone, Ilaria, D'Andrea, Giuseppe, Galatolo, Michela, Tortelli, Andrea, Tagliabue, Ilaria, Turco, Marco, Pompili, Maurizio, Selten, Jean-Paul, de Haan, Lieuwe, Rossi Menezes, Paulo, Del Ben, Cristina M., Santos, Jose Luis, Arrojo, Manuel, Bobes, Julio, Sanjuán, Julio, Bernardo, Miguel, Arango, Celso, Kirkbride, James B., Jones, Peter B., O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379, Rutten, Bart P., Van Os, Jim, Morgan, Craig, Sham, Pak C., Austin-Zimmerman, Isabelle, Li, Zhikun, Vassos, Evangelos, Murray, Robin M. and Di Forti, Marta
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Yuan, Kai, Longchamps, Ryan, Pardiñas, Antonio ORCID: https://orcid.org/0000-0001-6845-7590, Yu, Mingrui, Chen, Tzu-Ting, Lin, Shu-Chin, Chen, Yu, Lam, Max, Daly, Mark, Neale, Benjamine, Yen-Feng, Lin, Chen, Chia-Yen, O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379, Ge, Tian and Huang, Hailiang
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Clifton, Nicholas ORCID: https://orcid.org/0000-0003-2597-5253, Schulmann, Anton, Schizophrenia Working Group of the Psychiatric Genomics Consorti, Holmans, Peter ORCID: https://orcid.org/0000-0003-0870-9412, O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379 and Vawter, Marquis
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Palmer, Duncan, Howrigan, Daniel, Chapman, Sinead, Adolfsson, Rolf, Bass, Nick, Blackwood, Douglas, Boks, Marco, Chen, Chia-Yen, Churchhouse, Claire, Corvin, Aiden, Craddock, Nicholas ORCID: https://orcid.org/0000-0003-2171-0610, Curtis, David, Di Florio, Arianna ORCID: https://orcid.org/0000-0003-0338-2748, Dickerson, Faith, Freimer, Nelson, Goes, Fernando, Jia, Xiaoming, Jones, Ian ORCID: https://orcid.org/0000-0001-5821-5889, Jones, Lisa ORCID: https://orcid.org/0000-0001-5821-5889, Jonsson, Lina, Kahn, Rene, Landen, Mikael, Locke, Adam, McIntosh, Andrew, McQuillin, Andrew, Morris, Derek, O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379, Ophoff, Roel, Owen, Michael ORCID: https://orcid.org/0000-0003-4798-0862, Pedersen, Nancy, Posthuma, Danielle, Reif, Andreas, Risch, Neil, Schaefer, Catherine, Scott, Laura, Singh, Tarjinder, Smoller, Jordan, Solomonson, Matthew, St Clair, David, Stahl, Eli, Vreeker, Annabel, Walters, James ORCID: https://orcid.org/0000-0002-6980-4053, Wang, Weiqing, Watts, Nicholas, Yolken, Robert, Zandi, Peter and Neale, Benjamin
2022.
Exome sequencing in bipolar disorder reveals AKAP11 as a risk gene shared with schizophrenia.
Nature Genetics
10.1038/s41588-022-01034-x
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ORCID: https://orcid.org/0000-0003-0870-9412, Boland, Anne, Damotte, Vincent, van der Lee, Sven J., Costa, Marcos R., Kuulasmaa, Teemu, Yang, Qiong, de Rojas, Itziar, Bis, Joshua C., Yaqub, Amber, Prokic, Ivana, Chapuis, Julien, Ahmad, Shahzad, Giedraitis, Vilmantas, Aarsland, Dag, Garcia-Gonzalez, Pablo, Abdelnour, Carla, Alarcón-Martín, Emilio, Alcolea, Daniel, Alegret, Montserrat, Alvarez, Ignacio, Álvarez, Victoria, Armstrong, Nicola J., Tsolaki, Anthoula, Antúnez, Carmen, Appollonio, Ildebrando, Arcaro, Marina, Archetti, Silvana, Pastor, Alfonso Arias, Arosio, Beatrice, Athanasiu, Lavinia, Bailly, Henri, Banaj, Nerisa, Baquero, Miquel, Barral, Sandra, Beiser, Alexa, Pastor, Ana Belén, Below, Jennifer E., Benchek, Penelope, Benussi, Luisa, Berr, Claudine, Besse, Céline, Bessi, Valentina, Binetti, Giuliano, Bizarro, Alessandra, Blesa, Rafael, Boada, Mercè, Boerwinkle, Eric, Borroni, Barbara, Boschi, Silvia, Bossù, Paola, Bråthen, Geir, Bressler, Jan, Bresner, Catherine ORCID: https://orcid.org/0000-0003-2673-9762, Brodaty, Henry, Brookes, Keeley J., Brusco, Luis Ignacio, Buiza-Rueda, Dolores, Bûrger, Katharina, Burholt, Vanessa, Bush, William S., Calero, Miguel, Cantwell, Laura B., Chene, Geneviève, Chung, Jaeyoon, Cuccaro, Michael L., Carracedo, Ángel, Cecchetti, Roberta, Cervera-Carles, Laura, Charbonnier, Camille, Chen, Hung-Hsin, Chillotti, Caterina, Ciccone, Simona, Claassen, Jurgen A. 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T., Reitz, Christiane, Reyes-Dumeyer, Dolly, Ridge, Perry, Riedel-Heller, Steffi, Riederer, Peter, Roberto, Natalia, Rodriguez-Rodriguez, Eloy, Rongve, Arvid, Allende, Irene Rosas, Rosende-Roca, Maitée, Royo, Jose Luis, Rubino, Elisa, Rujescu, Dan, Sáez, María Eugenia, Sakka, Paraskevi, Saltvedt, Ingvild, Sanabria, Ángela, Sánchez-Arjona, María Bernal, Sanchez-Garcia, Florentino, Juan, Pascual Sánchez, Sánchez-Valle, Raquel, Sando, Sigrid B., Sarnowski, Chloé, Satizabal, Claudia L., Scamosci, Michela, Scarmeas, Nikolaos, Scarpini, Elio, Scheltens, Philip, Scherbaum, Norbert, Scherer, Martin, Schmid, Matthias, Schneider, Anja, Schott, Jonathan M., Selbæk, Geir, Seripa, Davide, Serrano, Manuel, Sha, Jin, Shadrin, Alexey A., Skrobot, Olivia, Slifer, Susan, Snijders, Gijsje J. L., Soininen, Hilkka, Solfrizzi, Vincenzo, Solomon, Alina, Song, Yeunjoo, Sorbi, Sandro, Sotolongo-Grau, Oscar, Spalletta, Gianfranco, Spottke, Annika, Squassina, Alessio, Stordal, Eystein, Tartan, Juan Pablo, Tárraga, Lluís, Tesí, Niccolo, Thalamuthu, Anbupalam, Thomas, Tegos, Tosto, Giuseppe, Traykov, Latchezar, Tremolizzo, Lucio, Tybjærg-Hansen, Anne, Uitterlinden, Andre, Ullgren, Abbe, Ulstein, Ingun, Valero, Sergi, Valladares, Otto, Broeckhoven, Christine Van, Vance, Jeffery, Vardarajan, Badri N., van der Lugt, Aad, Dongen, Jasper Van, van Rooij, Jeroen, van Swieten, John, Vandenberghe, Rik, Verhey, Frans, Vidal, Jean-Sébastien, Vogelgsang, Jonathan, Vyhnalek, Martin, Wagner, Michael, Wallon, David, Wang, Li-San, Wang, Ruiqi, Weinhold, Leonie, Wiltfang, Jens, Windle, Gill, Woods, Bob, Yannakoulia, Mary, Zare, Habil, Zhao, Yi, Zhang, Xiaoling, Zhu, Congcong, Zulaica, Miren, Laczo, Jan, Matoska, Vaclav, Serpente, Maria, Assogna, Francesca, Piras, Fabrizio, Piras, Federica, Ciullo, Valentina, Shofany, Jacob, Ferrarese, Carlo, Andreoni, Simona, Sala, Gessica, Zoia, Chiara Paola, Zompo, Maria Del, Benussi, Alberto, Bastiani, Patrizia, Takalo, Mari, Natunen, Teemu, Laatikainen, Tiina, Tuomilehto, Jaakko, Antikainen, Riitta, Strandberg, Timo, Lindström, Jaana, Peltonen, Markku, Abraham, Richard, Al-Chalabi, Ammar, Bass, Nicholas J., Brayne, Carol, Brown, Kristelle S., Collinge, John, Craig, David, Deloukas, Pangiotis, Fox, Nick, Gerrish, Amy, Gill, Michael, Gwilliam, Rhian, Harold, Denise, Hollingworth, Paul, Johnston, Jarret A., Jones, Lesley ORCID: https://orcid.org/0000-0002-3007-4612, Lawlor, Brian, Livingston, Gill, Lovestone, Simon, Lupton, Michelle, Lynch, Aoibhinn, Mann, David, McGuinness, Bernadette, McQuillin, Andrew, O'Donovan, Michael C. 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Khalid, Todhunter, Catherine E., Mansfield, John C., Ahmad, Tariq, Cummings, Fraser R., Jewell, Derek P., Webster, John, Brown, Morris J., Clayton, David G., Lathrop, Mark G., Connell, John, Dominiczak, Anna, Samani, Nilesh J., Marcano, Carolina A Braga, Burke, Beverley, Dobson, Richard, Gungadoo, Johannie, Lee, Kate L., Munroe, Patricia B., Newhouse, Stephen J., Onipinla, Abiodun, Wallace, Chris, Xue, Mingzhan, Caulfield, Mark, Farrall, Martin, Barton, Anne, Bruce, Ian N., Donovan, Hannah, Eyre, Steve, Gilbert, Paul D., Hilder, Samantha L., Hinks, Anne M., John, Sally L., Potter, Catherine, Silman, Alan J., Symmons, Deborah P. M., Thomson, Wendy, Worthington, Jane, Clayton, David G., Dunger, David B., Nutland, Sarah, Stevens, Helen E., Walker, Neil M., Widmer, Barry, Todd, John A., Frayling, Timothy M., Freathy, Rachel M., Lango, Hana, Perry, John R. B., Shields, Beverley M., Weedon, Michael N., Hattersley, Andrew T., Hitman, Graham A., Walker, Mark, Elliott, Kate S., Groves, Christopher J., Lindgren, Cecilia M., Rayner, Nigel W., Timpson, Nicolas J., Zeggini, Eleftheria, McCarthy, Mark I., Newport, Melanie, Sirugo, Giorgio, Lyons, Emily, Vannberg, Fredrik, Hill, Adrian V. S., Bradbury, Linda A., Farrar, Claire, Pointon, Jennifer J., Wordsworth, Paul, Brown, Matthew A., Franklyn, Jayne A., Heward, Joanne M., Simmonds, Matthew J., Gough, Stephen C. L., Seal, Sheila, Stratton, Michael R., Rahman, Nazneen, Ban, Maria, Goris, An, Sawcer, Stephen J., Compston, Alastair, Conway, David, Jallow, Muminatou, Newport, Melanie, Sirugo, Giorgio, Rockett, Kirk A., Kwiatkowski, Dominic P., Bumpstead, Suzannah J., Chaney, Amy, Downes, Kate, Ghori, Mohammed J. 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2007.
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.
Nature Genetics
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Harold, D, Paracchini, S, Scerri, T, Dennis, M, Cope, N, Hill, G, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Walter, J, Richardson, A J, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Stein, J F, Green, E D, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Williams, J and Monaco, A P
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Further evidence that the KIAA0319 gene confers susceptibility to developmental dyslexia.
Molecular Psychiatry
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10.1038/sj.mp.4001904
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O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379, Scambler, P. J, Paylora, R, Glaser, B, Mupod, A, Ataliotis, P, Spencer, C, Sobotka, A, Sparks, C, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862
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Genetic dissection of behavioural abnormalities in mouse models of DiGeorge/velocardiofacial syndrome.
Journal of intellectual disability research
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Zammit, Stanley ORCID: https://orcid.org/0000-0002-2647-9211, Lewis, G., Thapar, Anita ORCID: https://orcid.org/0000-0002-3689-737X, Owen, R., Jones, G., Jones, S., Sanders, R., Milham, C., Mahdi, A., O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862
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Phenotypic variation between parent-offspring trios and non-trios in genetic studies of schizophrenia.
Journal of Psychiatric Research
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10.1016/j.jpsychires.2005.05.006
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Li, Yonghong, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, Brayne, Carol, Rowland, Charles, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Morris, John C and Maxwell, Taylor J
2006.
DAPK1 variants are associated with Alzheimer's disease and allele-specific expression.
Human Molecular Genetics
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10.1093/hmg/ddl178
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Talkowski, Michael E., Seltman, Howard, Bassett, Anne S., Brzustowicz, Linda M., Chen, Xiangning, Chowdari, Kodavali V., Collier, David A., Cordeiro, Quirino, Corvin, Aiden P., Deshpande, Smita N., Egan, Michael F., Gill, Michael, Kendler, Kenneth S., Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950, Heston, Leonard L., Levitt, Pat, Lewis, David A., Li, Tao, Mirnics, Karoly, Morris, Derek W., Norton, Nadine, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Richard, Christian, Semwal, Prachi, Sobell, Janet L., St Clair, David, Straub, Richard E., Thelma, B.K., Vallada, Homero, Weinberger, Daniel R., Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Wood, Joel, Zhang, Feng, Devlin, Bernie and Nimgaonkar, Vishwajit L.
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Evaluation of a susceptibility gene for schizophrenia: genotype based meta-analysis of RGS4 polymorphisms from thirteen independent samples.
Biological psychiatry
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10.1016/j.biopsych.2006.02.015
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Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
2006.
The genetics of developmental dyslexia.
European Journal of Human Genetics
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10.1038/sj.ejhg.5201575
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Hamilton, Gillian, Samedi, Farzana, Knight, Jo, Archer, Nicola, Foy, Catherine, Walter, Sarah, Turic, Dragana, Jehu, Luke, Moore, Pamela, Hollingworth, Paul, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Lovestone, Simon and Powell, John F.
2006.
Polymorphisms in the phosphate and tensin homolog gene are not associated with late-onset Alzheimer's disease.
Neuroscience Letters
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10.1016/j.neulet.2006.03.021
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Paylor, R., Glaser, B., Mupo, A., Ataliotis, P., Spencer, C., Sobotka, A., Sparks, C., Choi, C.-H., Oghalai, J., Curran, S., Murphy, K. C., Monks, S., Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Scambler, P. J. and Lindsay, E.
2006.
Tbx1 haploinsufficiency is linked to behavioral disorders in mice and humans: Implications for 22q11 deletion syndrome.
Proceedings of the National Academy of Sciences of the United States of America
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10.1073/pnas.0600206103
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Pooled DNA genotyping on Affymetrix SNP genotyping arrays.
BMC Genomics
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Harold, Denise, Macgregor, S., Patterson, C. E., Hollingworth, P., Moore, P., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Passmore, P., McIlroy, S. and Jones, Lesley ORCID: https://orcid.org/0000-0002-3007-4612
2006.
A single nucleotide polymorphism in CHAT influences response to acetylcholinesterase inhibitors in Alzheimer's disease.
Pharmacogenetics and genomics
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Khan, Imtiaz Ali, Mort, Matthew, Buckland, Paul Robert, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Cooper, D. N. and Chuzhanova, N. A.
2006.
In silico discrimination of single nucleotide polymorphisms and pathological mutations in human gene promoter regions by means of local DNA sequence context and regularity.
In silico Biology
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Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862
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Chromosome 22 deletion syndrome and schizophrenia.
International Review of Neurobiology
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Smemo, S1, Nowotny, P., Hinrichs, A. L., Kauwe, J. S., Cherny, S., Erickson, K, Myers, A. J., Kaleem, M., Marlowe, L., Gibson, A. M., Hollingworth, P., O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Morris, C. M., Holmans, Peter Alan ORCID: https://orcid.org/0000-0003-0870-9412, Lovestone, S., Morris, J. C., Thal, L., Li, Y., Grupe, A., Hardy, J., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Williams, J. and Goate, A.
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Ubiquilin 1 polymorphisms are not associated with late-onset Alzheimer's disease.
Annals of Neurology
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Grupe, Andrew, Li, Yonghong, Rowland, Charles, Nowotny, Petra, Hinrichs, Anthony L., Smemo, Scott, Kauwe, John S. K., Maxwell, Taylor J., Cherny, Sara, Doil, Lisa, Tacey, Kristina, Luchene, Ryan van, Myers, Amanda, Wavrant-De Vrièze, Fabienne, Kaleem, Mona, Hollingworth, Paul, Jehu, Luke, Foy, Catherine, Archer, Nicola, Hamilton, Gillian, Holmans, Peter Alan ORCID: https://orcid.org/0000-0003-0870-9412, Morris, Chris M., Catanese, Joseph, Sninsky, John, White, Thomas J., Powell, John, Hardy, John, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Lovestone, Simon, Jones, Lesley ORCID: https://orcid.org/0000-0002-3007-4612, Morris, John C., Thal, Leon, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259 and Goate, Alison
2006.
A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
The American Journal of Human Genetics
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Peirce, Timothy Rowan, Bray, Nicholas John ORCID: https://orcid.org/0000-0002-4357-574X, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Norton, Nadine ORCID: https://orcid.org/0000-0002-3848-4288, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Preece, Anna Charlotte, Haroutunian, Vahram, Buxbaum, Joseph D., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
2006.
Convergent evidence for 2',3'-cyclic nucleotide 3'-phosphodiesterase as a possible susceptibility gene for schizophrenia.
Archives of general psychiatry
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Peirce, TR, Bray, Nicholas John ORCID: https://orcid.org/0000-0002-4357-574X, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Norton, N, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Preece, Anna, Haroutunian, V, Buxbaum, JD, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
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Convergent evidence for 2 ',3 '-cyclic nucleotide 3 '-phosphodiesterase as a possible susceptibility gene for schizophrenia.
Archives of General Psychiatry
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Hamshere, Marian Lindsay ORCID: https://orcid.org/0000-0002-8990-0958, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Norton, Nadine ORCID: https://orcid.org/0000-0002-3848-4288, Williams, H., Cardno, Alastair G., Zammit, Stanley ORCID: https://orcid.org/0000-0002-2647-9211, Jones, L. A., Murphy, K. C., Sanders, Rebecca, McCarthy, G., Gray, M. Y., Jones, G., Holmans, Peter Alan ORCID: https://orcid.org/0000-0003-0870-9412, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610
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Genome wide significant linkage in schizophrenia conditioning on occurrence of depressive episodes.
Journal of Medical Genetics
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10.1136/jmg.2005.035345
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Green, Elaine K., Baybould, Rachel, MacGregor, Stuart, Hyde, Sally, Young, Allan H., O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950, Jones, Lisa, Jones, Ian Richard ORCID: https://orcid.org/0000-0001-5821-5889 and Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610
2006.
Genetic variation of brain-derived neurotrophic factor (BDNF) in bipolar disorder: case-control study of over 3000 individuals from the UK.
British Journal of Psychiatry
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10.1192/bjp.bp.105.009969
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Langley, Kate ORCID: https://orcid.org/0000-0002-2033-2657, Turic, D., Peirce, T. R., Mills, S., van den Bree, Marianne Bernadette ORCID: https://orcid.org/0000-0002-4426-3254, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and Thapar, Anita ORCID: https://orcid.org/0000-0002-3689-737X
2005.
No support for association between the dopamine transporter (DAT1) gene and ADHD.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
139B
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10.1002/ajmg.b.30206
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Gough, S. C. and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
2005.
Clustering of metabolic comorbidity in schizophrenia: a genetic contribution?
Journal of Psychopharmacology
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10.1177/0269881105058380
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Buckland, Paul Robert, Hoogendoorn, Bastiaan ORCID: https://orcid.org/0000-0001-9753-169X, Coleman, Sharon Louise, Guy, Carol, Smith, Susan Kaye and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
2005.
Strong bias in the location of functional promoter polymorphisms.
Human Mutation
26
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10.1002/humu.20207
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Williams, H. J., Glaser, B., Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Norton, N., Zammit, Stanley ORCID: https://orcid.org/0000-0002-2647-9211, MacGregor, S., Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
2005.
No association between schizophrenia and polymorphisms in COMT in two large samples.
American Journal of Psychiatry
162
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10.1176/appi.ajp.162.9.1736
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Redfern, A., Hughes, G., McGuffin, P., Aitchison, K., Vollmayr, B., Gass, P., O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610 and Jones, Lesley ORCID: https://orcid.org/0000-0002-3007-4612
2005.
Global gene expression profiling in the hippocampus and frontal cortex of Escitalopram-treated Learned Helplessness rats.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
138B
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Nowotny, P., Hinrichs, A. L., Smemo, S., Kauwe, J. S., Maxwell, T., Holmans, Peter Alan ORCID: https://orcid.org/0000-0003-0870-9412, Hamshere, Marian Lindsay ORCID: https://orcid.org/0000-0002-8990-0958, Turic, D., Jehu, L., Hollingworth, P., Moore, P., Bryden, L., Myers, A., Doil, L. M., Tacey, K. M., Gibson, A. M., McKeith, I. G., Perry, R. H., Morris, C. M., Thal, L., Morris, J. C., O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Lovestone, S. and Grupe, A.
2005.
Association studies between risk for late-onset Alzheimer's disease and variants in insulin degrading enzyme.
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
136B
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10.1002/ajmg.b.30186
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Glaser, B1, Schumacher, J., Williams, H. J., Jamra, R. A., Ianakiev, N., Milev, R., Ohlraun, S., Schulze, T. G., Czerski, P. M., Hauser, J., Jonsson, E. G., Sedvall, G. C., Klopp, N., Illig, T., Becker, T., Propping, P., Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Cichon, S., Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950, Rietschel, M., Murphy, K. C., O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Nothen, M. M. and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862
2005.
No association between the putative functional ZDHHC8 single nucleotide polymorphism rs175174 and schizophrenia in large European samples.
Biological psychiatry
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Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862
2005.
Finding schizophrenia genes.
The Journal of Clinical Investigation
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10.1172/JCI24759
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Green, Elaine Karen, Raybould, Rachel, Macgregor, Stuart, Gordon-Smith, Katherine Mary, Heron, Jess, Hyde, Sally, Grozeva, Detelina ORCID: https://orcid.org/0000-0003-3239-8415, Hamshere, Marian Lindsay ORCID: https://orcid.org/0000-0002-8990-0958, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Jones, Lisa Anne, Jones, Ian Richard ORCID: https://orcid.org/0000-0001-5821-5889, Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950 and Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610
2005.
Operation of the schizophrenia susceptibility gene, neuregulin 1, across traditional diagnostic boundaries to increase risk for bipolar disorder.
Archives of general psychiatry
62
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10.1001/archpsyc.62.6.642
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Norton, Nadine, Williams, Hywel, Dwyer, Sarah, Ivanov, Dobril ORCID: https://orcid.org/0000-0001-6271-6301, Preece, Anna, Gerrish, Amy, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Yerassimou, P., Zammit, Stanley ORCID: https://orcid.org/0000-0002-2647-9211, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862
2005.
No evidence for association between polymorphisms in GRM3 and schizophrenia.
BMC Psychiatry
5
, 23.
10.1186/1471-244X-5-23
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Bray, Nicholas John ORCID: https://orcid.org/0000-0002-4357-574X, Preece, Anna Charlotte, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Buckland, Paul Robert, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
2005.
Haplotypes at the dystrobrevin binding protein 1 (DTNBP1) gene locus mediate risk for schizophrenia through reduced DTNBP1 expression.
Human Molecular Genetics
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10.1093/hmg/ddi199
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Cope, Natalie Alexandra, Harold, Denise ORCID: https://orcid.org/0000-0001-5195-0143, Hill, Gary Trevor, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Stevenson, Jim, Holmans, Peter Alan ORCID: https://orcid.org/0000-0003-0870-9412, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, O’Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259
2005.
Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia.
American Journal of Human Genetics
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10.1086/429131
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Buckland, Paul Robert, Hoogendoorn, Bastiaan ORCID: https://orcid.org/0000-0001-9753-169X, Guy, Carol, Smith, Susan Kaye, Coleman, Sharon Louise and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
2005.
Low gene expression conferred by association of an allele of the 5-HT2C receptor gene with antipsychotic-induced weight gain.
American Journal of Psychiatry
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, pp. 613-615.
10.1176/appi.ajp.162.3.613
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Li, Y., Hollingworth, P., Moore, P., Foy, C., Archer, N., Powell, J., Nowotny, P., Holmans, Peter Alan ORCID: https://orcid.org/0000-0003-0870-9412, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Tacey, K., Doil, L., van Luchene, R., Garcia, V., Rowland, V., Lau, K., Cantanese, J., Sninsky, J., Hardy, J., Thal, L., Morris, J. C., Goate, A., Lovestone, S., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259 and Grupe, A.
2005.
Genetic association of the APP binding protein 2 gene (APBB2) with late onset Alzheimer disease.
Human Mutation
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10.1002/humu.20138
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Cope, N. A., Hill, G., van den Bree, Marianne Bernadette ORCID: https://orcid.org/0000-0002-4426-3254, Harold, D., Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Green, E. K., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
2005.
No support for association between dyslexia susceptibility 1 candidate 1 and developmental dyslexia.
Molecular Psychiatry
10
(3)
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10.1038/sj.mp.4001596
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Turic, D., Williams, Hywel, Langley, Kate ORCID: https://orcid.org/0000-0002-2033-2657, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Thapar, Anita ORCID: https://orcid.org/0000-0002-3689-737X and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
2005.
A family based study of catechol-O-methyltransferase (COMT) and attention deficit hyperactivity disorder (ADHD).
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
133B
(1)
, pp. 64-67.
10.1002/ajmg.b.30123
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Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and Harrison, P. J.
2005.
Schizophrenia: a genetic disorder of the synapse?
British Medical Journal (BMJ)
330
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, pp. 158-159.
10.1136/bmj.330.7484.158
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Raybould, Rachel, Green, Elaine K., MacGregor, Stuart, Gordon-Smith, Katherine, Heron, Jess, Hyde, Sally, Caesar, Sian, Nikolov, Ivan, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Jones, Lisa, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Jones, Ian Richard ORCID: https://orcid.org/0000-0001-5821-5889, Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950 and Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610
2005.
Bipolar disorder and polymorphisms in the dysbindin gene (DTNBP1).
Biological psychiatry
57
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, pp. 696-701.
10.1016/j.biopsych.2005.01.018
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Kent, L., Green, Elaine, Hawi, Z., Kirley, A., Dudbridge, F., Lowe, N., Raybould, Rachel, Langley, Kate ORCID: https://orcid.org/0000-0002-2033-2657, Bray, Nicholas John ORCID: https://orcid.org/0000-0002-4357-574X, Fitzgerald, M., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Gill, M., Thapar, Anita ORCID: https://orcid.org/0000-0002-3689-737X and Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610
2005.
Association of the paternally transmitted copy of common Valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene with susceptibility to ADHD.
Molecular Psychiatry
10
(10)
, pp. 939-943.
10.1038/sj.mp.4001696
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Buckland, Paul Robert, Hoogendoorn, Bastiaan ORCID: https://orcid.org/0000-0001-9753-169X, Guy, C. A., Coleman, S. L., Smith, S. K., Buxbaum, J. D., Hartoutunian, V. and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
2004.
A high proportion of polymorphisms in the promoters of brain expressed genes influences transcriptional activity.
Acta Biochimica et Biophysica
1690
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, pp. 238-249.
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Bray, Nicholas John ORCID: https://orcid.org/0000-0002-4357-574X, Preece, Anna, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Williams, HJ, Norton, N, Wilkinson, J, Buckland, Paul Robert, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
2004.
Allelic variation in the expression of neuropsychiatric candidate genes [Conference Abstract].
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
130B
(1)
, p. 25.
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Peirce, T. R., Bray, Nicholas John ORCID: https://orcid.org/0000-0002-4357-574X, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Haroutunian, V., Buxbaum, J., Buckland, Paul Robert, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
2004.
Convergent functional genomics, association and linkage analysis suggests 2 ',3 '-cyclic nucleotide 3 '-phosphodiesterase (CNP) as a potential susceptibility gene for schizophrenia [Conference Abstract].
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
130B
(1)
, p. 81.
10.1002/ajmg.b.30101
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Fowler, T. A., Thapar, Anita ORCID: https://orcid.org/0000-0002-3689-737X, Langley, Kate ORCID: https://orcid.org/0000-0002-2033-2657, Turic, Dragana, Whittinger, N., van den Bree, Marianne Bernadette ORCID: https://orcid.org/0000-0002-4426-3254, Aggleton, John Patrick ORCID: https://orcid.org/0000-0002-5573-1308, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
2004.
Early onset antisocial behaviour in children with ADHD is associated with a functional variant in the catechol-O-methyltransferase (COMT) gene [Abstract].
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
130B
(1)
, p. 98.
10.1002/ajmg.b.30101
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Bray, Nicholas John ORCID: https://orcid.org/0000-0002-4357-574X, Jehu, Luke, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Buckland, Paul Robert, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
2004.
Allelic expression of APOE in brain [Conference Abstract].
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
130B
(1)
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Norton, N, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Morris, DW, Bray, Nicholas John ORCID: https://orcid.org/0000-0002-4357-574X, Zammit, Stanley ORCID: https://orcid.org/0000-0002-2647-9211, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Williams, HJ, Preece, Anna, Dwyer, SL, Wilkinson, JC, Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950, Buckland, Paul Robert, Waddington, JL, Gill, M, Corvin, AP, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
2004.
Interaction between neuregulin 1 and its receptor ERBB4 increases susceptibility to schizophrenia [Conference Abstract].
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
130B
(1)
, p. 18.
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Mowry, B J, Holmans, Peter Alan ORCID: https://orcid.org/0000-0003-0870-9412, Pulver, A E, Gejman, P V, Riley, B, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Laurent, C, Schwab, S G, Wildenauer, D B, Bauché, S, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Wormley, B, Sanders, A R, Nestadt, G, Liang, K Y, Duan, J, Ribble, R, Norton, N, Soubigou, S, Maier, W, Ewen-White, K R, deMarchi, N, Carpenter, B, Walsh, D, Williams, H, Jay, M, Albus, M, Nertney, D A, Papadimitriou, G, O'Neill, A, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Deleuze, J-F, Lerer, F B, Dikeos, D, Kendler, K S, Mallet, J, Silverman, J M, Crowe, R R and Levinson, D F
2004.
Multicenter linkage study of schizophrenia loci on chromosome 22q.
Molecular Psychiatry
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10.1038/sj.mp.4001481
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Morris, D.W., Ivanov, D. ORCID: https://orcid.org/0000-0001-6271-6301, Robinson, L., Williams, N. ORCID: https://orcid.org/0000-0003-1177-6931, Stevenson, J., Owen, M. J. ORCID: https://orcid.org/0000-0003-4798-0862, Williams, J. and O'Donovan, M. C. ORCID: https://orcid.org/0000-0001-7073-2379
2004.
Association analysis of two candidate phospholipase genes that map to the chromosome 15q15.1-15.3 region associated with reading disability.
American Journal Of Medical Genetics Part A
129B
(1)
, pp. 97-103.
10.1002/ajmg.b.30033
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Zammit, Stanley ORCID: https://orcid.org/0000-0002-2647-9211, Jones, Gaynor, Jones, Susan J., Norton, Nadine, Sanders, Robert D., Milham, Charis, McCarthy, Geraldine M., Jones, Lisa A., Cardno, Alastair G., Gray, Marion, Murphy, Kieran C., O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862
2004.
Polymorphisms in the MAOA, MAOB, and COMT genes and aggressive behavior in schizophrenia.
American Journal of Medical Genetics
128B
(1)
, pp. 19-20.
10.1002/ajmg.b.30021
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Hoogendoorn, Bastiaan ORCID: https://orcid.org/0000-0001-9753-169X, Coleman, Sharon Louise, Guy, Carol, Smith, Susan Kaye, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and Buckland, Paul Robert
2004.
Functional analysis of polymorphisms in the promoter regions of genes on 22q11.
Human Mutation
24
(1)
, pp. 35-42.
10.1002/humu.20061
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Plomin, R, Turic, D M, Hill, L, Turic, D E, Stephens, M, Williams, J, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
2004.
A functional polymorphism in the succinate-semialdehyde dehydrogenase (aldehyde dehydrogenase 5 family, member A1) gene is associated with cognitive ability.
Molecular Psychiatry
9
(6)
, pp. 582-586.
10.1038/sj.mp.4001441
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Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950, Ivanov, Dobril ORCID: https://orcid.org/0000-0001-6271-6301, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Preece, Anna Charlotte, Nikolov, Ivan, Milev, Radoi, Koleva, Svetlinka, Dimitrova, Albena, Toncheva, Draga, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862
2004.
Strong evidence for association between the dystrobrevin binding protein 1 gene (DTNBP1) and schizophrenia in 488 parent-offspring trios from Bulgaria.
Biological psychiatry
55
(10)
, pp. 971-975.
10.1016/j.biopsych.2004.01.025
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Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
2004.
Dysbindin-1 and schizophrenia: from genetics to neuropathology.
The Journal of Clinical Investigation
113
(9)
, pp. 1255-1257.
10.1172/JCI200421470
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Murphy, K.C., Williams, H.J., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
2004.
What can velo-cardio-facial syndrome tell us about the genetics of schizophrenia?
European Psychiatry
19
(Supp1)
, 96S-96S.
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Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Preece, Anna, Mortis, DW, Spurlock, Gillian, Bray, Nicholas John ORCID: https://orcid.org/0000-0002-4357-574X, Stephens, M, Norton, N, Williams, H, Clement, M, Dwyer, S, Curran, C, Wilkinson, J, Escott-Price, Valentina ORCID: https://orcid.org/0000-0003-1784-5483, Waddington, JL, Gill, M, Corvin, AP, Zammit, Stanley ORCID: https://orcid.org/0000-0002-2647-9211, Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
2004.
Identification in 2 independent samples of a novel schizophrenia risk haplotype of the dystrobrevin binding protein gene (DTNBP1).
Archives of General Psychiatry
61
(4)
, pp. 336-344.
10.1001/archpsyc.61.4.336
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Huezo-Diaz, P., Arranz, M.J., Munro, J., Osborne, S., Makoff, A., Kerwin, R.W., Austin, J. and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
2004.
An association study of the neurotensin receptor gene with schizophrenia and clozapine response.
Schizophrenia Research
66
(2-3)
, pp. 193-195.
10.1016/S0920-9964(03)00128-2
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Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Preece, Anna Charlotte, Spurlock, Gillian, Norton, Nadine ORCID: https://orcid.org/0000-0002-3848-4288, Williams, Hywel John ORCID: https://orcid.org/0000-0001-7758-0312, McCreadie, Robin G, Buckland, Paul Robert, Sharkey, Val, Chowdari, Kodavali V., Zammit, Stanley ORCID: https://orcid.org/0000-0002-2647-9211, Nimgaonkar, Vishwajit, Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
2004.
Support for RGS4 as a susceptibility gene for schizophrenia.
Biological Psychiatry
55
(2)
, pp. 192-195.
10.1016/j.biopsych.2003.11.002
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Guy, Carol, Hoogendoorn, Bastiaan ORCID: https://orcid.org/0000-0001-9753-169X, Smith, Susan Kay, Coleman, Sharon Louise, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and Buckland, Paul Robert
2004.
Promoter polymorphisms in glutathione-S-transferase genes affect transcription.
Pharmacogenetics
14
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, pp. 45-51.
10.1097/00008571-200401000-00005
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Myers, Amanda J., Marshall, Helen, Holmans, Peter Alan ORCID: https://orcid.org/0000-0003-0870-9412, Compton, Danielle, Crook, Richard J.P., Mander, Adrian P., Nowotny, Petra, Smemo, Scott, Dunstan, Melanie ORCID: https://orcid.org/0000-0003-3817-2142, Jehu, Luke, Wang, Jen C., Hamshere, Marian Lindsay ORCID: https://orcid.org/0000-0002-8990-0958, Morris, John C., Norton, Joanne, Chakraventy, Sumi, Tunstall, Nigel, Lovestone, Simon, Petersen, Ronald, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Jones, Lesley ORCID: https://orcid.org/0000-0002-3007-4612, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Hardy, John and Goate, Alison
2004.
Variation in the urokinase-plasminogen activator gene does not explain the chromosome 10 linkage signal for late onset AD.
American Journal of Medical Genetics
124B
(1)
, pp. 29-37.
10.1002/ajmg.b.20036
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Cichon, Sven, Buervenich, Silvia, Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950, Akula, Nirmala, Dimitrova, Albena, Green, Elaine, Schumacher, Johannes, Klopp, Norman, Becker, Tim, Ohlraun, Stephanie, Schulze, Thomas G, Tullius, Monja, Gross, Magdalena M, Jones, Lisa, Krastev, Stefan, Nikolov, Ivan, Hamshere, Marian Lindsay ORCID: https://orcid.org/0000-0002-8990-0958, Jones, Ian Richard ORCID: https://orcid.org/0000-0001-5821-5889, Czerski, Piotr M., Leszczynska-Rodziewicz, Anna, Kapelski, Pawel, Van Den Bogaert, Ann, Illig, Thomas, Hauser, Joanna, Maier, Wolfgang, Berrettini, Wade, Byerley, William, Coryell, William, Gershon, Elliot S., Kelsoe, John R., McInnis, Melvin G., Murphy, Dennis L., Nurnberger, John I., Reich, Theodore, Scheftner, William, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Propping, Peter, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Rietschel, Marcella, Nöthen, Markus M., McMahon, Francis J. and Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610
2004.
Lack of support for a genetic association of the XBP1 promoter polymorphism with bipolar disorder in probands of European origin.
Nature Genetics
36
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10.1038/ng0804-783
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Norton, Nadine, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862
2004.
DNA pooling as a tool for large-scale association studies in complex traits.
Annals of Medicine
36
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10.1080/07853890310021724
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Busby, Victoria, Goossens, Steven, Nowotny, Petra, Hamilton, Gillian, Smemo, Scott, Harold, Denise, Turic, Dragana, Jehu, Luke, Myers, Amanda, Womick, Meredith, Woo, Daniel, Compton, Danielle, Doil, Lisa M., Tacey, Kristina M., Lau, Kit F., Al-Saraj, Safa, Killick, Richard, Pickering-Brown, Stuart, Moore, Pamela, Hollingworth, Paul, Archer, Nicola, Foy, Catherine, Walter, Sarah, Lovestone, Simon, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Jones, Lesley ORCID: https://orcid.org/0000-0002-3007-4612, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259 and Holmans, Peter Alan ORCID: https://orcid.org/0000-0003-0870-9412
2004.
Alpha-T-Catenin Is Expressed in Human Brain and Interacts With the Wnt Signaling Pathway But Is Not Responsible for Linkage to Chromosome 10 in Alzheimer's Disease.
Neuromolecular Medicine
5
(2)
, pp. 133-146.
10.1385/NMM:5:2:133
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Bray, Nicholas John ORCID: https://orcid.org/0000-0002-4357-574X, Buckland, Paul Robert, Hall, H., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
2004.
The serotonin-2A receptor gene locus does not contain common polymorphism affecting mRNA levels in adult brain.
Molecular Psychiatry
9
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10.1038/sj.mp.4001366
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Bray, Nicholas John ORCID: https://orcid.org/0000-0002-4357-574X, Jehu, Luke, Moskvina, Vanentina, Buxbaum, Joseph D., Dracheva, Stella, Haroutunian, Vahram, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, Buckland, Paul Robert, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
2004.
Allelic expression of APOE in human brain: effects of epsilon status and promoter haplotypes.
Human Molecular Genetics
13
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10.1093/hmg/ddh299
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Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Norton, Nadine ORCID: https://orcid.org/0000-0002-3848-4288, Williams, Hywel John ORCID: https://orcid.org/0000-0001-7758-0312, Ekholm, B., Hamshere, Marian Lindsay ORCID: https://orcid.org/0000-0002-8990-0958, Lindblom, Y., Chowdari, K. V., Cardno, Alastair George, Zammit, Stanley ORCID: https://orcid.org/0000-0002-2647-9211, Jones, Lisa Anne, Murphy, Kieran Christopher, Sanders, Robert David, McCarthy, Geraldine MaryTeresa, Gray, Marion Yvonne, Jones, G., Holmans, Peter Alan ORCID: https://orcid.org/0000-0003-0870-9412, Nimgaonkar, V., Adolfson, R., Osby, U., Terenius, L., Sedvall, G., O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862
2003.
A systematic genomewide linkage study in 353 sib pairs with schizophrenia.
The American journal of human genetics
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10.1086/380206
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Smith, Susan Kay, Hoogendoorn, Bastiaan ORCID: https://orcid.org/0000-0001-9753-169X, Guy, Carol, Coleman, Sharon Louise, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and Buckland, Paul Robert
2003.
Lack of functional promoter polymorphisms in genes involved in glutamate neurotransmission.
Psychiatric Genetics
13
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10.1097/00041444-200312000-00001
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Abraham, Richard, Myers, Amanda, Wavrant-DeVrieze, Fabienne, Hamshere, Marian Lindsay ORCID: https://orcid.org/0000-0002-8990-0958, Thomas, Hollie Victoria, Marshall, Helen, Compton, Danielle, Spurlock, Gillian, Turic, Dragana, Hoogendoorn, Bastiaan ORCID: https://orcid.org/0000-0001-9753-169X, Kwon, Jennifer M., Petersen, Ronald C., Tangalos, Eric, Norton, Joanne, Morris, John C., Bullock, Roger, Liolitsa, Danae, Lovestone, Simon, Hardy, John, Goate, Alison, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and Jones, Lesley ORCID: https://orcid.org/0000-0002-3007-4612
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Substantial linkage disequilibrium across the insulin-degrading enzyme locus but no association with late-onset Alzheimer's disease.
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Kirov, George ORCID: https://orcid.org/0000-0002-3427-3950, Lowry, C. A., Stephens, M., Oldfield, S., O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Lightman, S. L. and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862
2001.
Screening ABCG1, the human homologue of the Drosophila white gene, for polymorphisms and association with bipolar affective disorder.
Molecular Psychiatry
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10.1038/sj.mp.4000899
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Williams, H.J. ORCID: https://orcid.org/0000-0001-7758-0312, Khazanehdari, K., Sutherland, H., Murphy, K.C., Jones, S., McCarthy, G.S., Jones, G., Zammit, S. ORCID: https://orcid.org/0000-0002-2647-9211, Cardno, A., Owen, R., Scambler, P., O'Donovan, M.C. ORCID: https://orcid.org/0000-0001-7073-2379 and Owen, M.J.
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Association analysis of TBX1 and schizophrenia.
American Journal of Medical Genetics - Neuropsychiatric Genetics
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Payton, A., Holmes, J., Barrett, J. H., Hever, T., Fitzpatrick, H., Trumper, A. L., Harrington, R., O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Ollier, W., Worthington, J. and Thapar, Anita ORCID: https://orcid.org/0000-0002-3689-737X
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Examining for association between candidate gene polymorphisms in the dopamine pathway and attention-deficit hyperactivity disorder: a family-based study.
Neuroscience Letters
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10.1002/ajmg.1407
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Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Norton, Nadine ORCID: https://orcid.org/0000-0002-3848-4288, Spurlock, G., Wittekindt, O. H., Morris-Rosendahl, D. J., Williams, Hywel John ORCID: https://orcid.org/0000-0001-7758-0312, Brzustowicz, L., Hoogendoorn, Bastiaan ORCID: https://orcid.org/0000-0001-9753-169X, Zammit, Stanley ORCID: https://orcid.org/0000-0002-2647-9211, Jones, G, Sanders, Rebecca, Jones, L. A., McCarthy, G., Jones, S., Bassett, A., Cardno, A. G., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
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Mutation screening of the KCNN3 gene reveals a rare frameshift mutation [Letter].
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Jacobsen, Nick J. O., Elvidge, Gareth, Franks, Emily K. E., O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610 and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862
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CUX2, a potential regulator of NCAM expression: Genomic characterization and analysis as a positional candidate susceptibility gene for bipolar disorder.
American Journal of Medical Genetics
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10.1002/ajmg.1325
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Jacobsen, N. J. O., Franks, E. K. E., Elvidge, G., Jones, Ian Richard ORCID: https://orcid.org/0000-0001-5821-5889, McCandless, F., O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610
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Exclusion of the Darier's disease gene, ATP2A2, as a common susceptibility gene for bipolar disorder.
Molecular Psychiatry
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10.1038/sj.mp.4000774
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Williams, N.M. ORCID: https://orcid.org/0000-0001-7758-0312, Spurlock, G., Williams, H. ORCID: https://orcid.org/0000-0001-7758-0312, Norton, N., Davis, K.L., Buxbaum, J.D., Haroutunian, V., Saunders, R., Cardno, A.G., McCarthy, G., O'Donovan, M.C. ORCID: https://orcid.org/0000-0001-7073-2379 and Owen, M.J. ORCID: https://orcid.org/0000-0003-4798-0862
2001.
Screening of candidate genes related to myelination for mutations associated with schizophrenia.
American Journal of Medical Genetics - Neuropsychiatric Genetics
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Vincent, John B., Qiu-Ping, Yuan, Schalling, Martin, Adolfsson, R., Azevedo, M. Helena, Macedo, Antonio, Bauer, Amy, Dalla Torre, Camille, Medeiros, Helena M., Pato, Carlos N., Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Guy, Carol, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Paterson, Andrew D., Petronis, Arturas and Kennedy, James L.
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Long repeat tracts at SCA8 in major psychosis.
American Journal of Medical Genetics
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10.1002/1096-8628(20001204)96:6<873::AID-AJMG37>3.0.CO;2-9
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Austin, J., Buckland, Paul Robert, Cardno, Alastair G., Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Spurlock, Gillian, Hoogendoorn, Bastiaan ORCID: https://orcid.org/0000-0001-9753-169X, Zammit, Stanley ORCID: https://orcid.org/0000-0002-2647-9211, Jones, G., Sanders, R., Jones, L., McCarthy, G., Jones, S., Bray, Nicholas John ORCID: https://orcid.org/0000-0002-4357-574X, McGuffin, Peter, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
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The high affinity neurotensin receptor gene (NTSR1): comparative sequencing and association studies in schizophrenia.
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10.1038/sj.mp.4000761
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Williams, H.J. ORCID: https://orcid.org/0000-0001-7758-0312, Murphy, K.C., Spurlock, G., O'Donovan, M.C. ORCID: https://orcid.org/0000-0001-7073-2379 and Owen, M.J. ORCID: https://orcid.org/0000-0003-4798-0862
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No association of the -277A variant allele of the UFD1L promoter polymorphism and schizophrenia.
American Journal of Medical Genetics - Neuropsychiatric Genetics
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Bray, Nicholas John ORCID: https://orcid.org/0000-0002-4357-574X, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Cardno, A. G., Gray, M., Jones, L. A., Murphy, K. C., Sanders, R., Spurlock, G., O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862
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No evidence for association between a non-synonymous polymorphism in the gene encoding human metabotropic glutamate receptor 7 and schizophrenia.
Psychiatric Genetics
10
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10.1097/00041444-200010020-00005
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Morris, D. W., Robinson, L., Turic, D., Duke, M., Webb, V., Milham, C., Hopkin, E., Pound, K., Fernando, S., Easton, M., Hamshere, Marian Lindsay ORCID: https://orcid.org/0000-0002-8990-0958, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, McGuffin, P., Stephenson, Jessica, Krawczak, M., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, O'Donovan, Michael ORCID: https://orcid.org/0000-0001-7073-2379 and Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259
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Family-based association mapping provides evidence for a gene for reading disability on chromosome 15q.
Human Molecular Genetics
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10.1093/hmg/9.5.843
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Austin, J., Hoogendoorn, Bastiaan ORCID: https://orcid.org/0000-0001-9753-169X, Buckland, Paul Robert, Jones, Ian Richard ORCID: https://orcid.org/0000-0001-5821-5889, McCandless, F., Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Middle, F., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
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Association analysis of the proneurotensin gene and bipolar disorder.
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Austin, J., Hoogendoorn, Bastiaan ORCID: https://orcid.org/0000-0001-9753-169X, Buckland, Paul Robert, Speight, G., Cardno, A., Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, Spurlock, G., Sanders, R., Jones, L., Murphy, Kevin, McCarthy, G., McGuffin, P., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
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Comparative sequencing of the proneurotensin gene and association studies in schizophrenia.
Molecular Psychiatry
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Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Guy, Carol, Cardno, A. G., Vincent, J. B., Kennedy, J. L., Jones, L. A., Gray, M, Sanders, Rhys, McCarthy, G, Murphy, K. C., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
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Repeat sizes at CAG/CTG loci CTG18.1, ERDA1 and TGC13-7a in schizophrenia.
Psychiatric Genetics
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Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Cardno, A. G. and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
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Psychiatric genetics: back to the future.
Molecular Psychiatry
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Genetic risk factors for schizophrenia.
International Journal of Mental Health
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Williams, N.M. ORCID: https://orcid.org/0000-0001-7758-0312, Bowen, T. ORCID: https://orcid.org/0000-0001-6050-0435, Spurlock, G., Williams, H. ORCID: https://orcid.org/0000-0001-7758-0312, Norton, N., Austin, J., Walters, A., Owen, M.J. ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, M.C. ORCID: https://orcid.org/0000-0001-7073-2379
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Identification and characterisation of SNPs in candidate genes for schizophrenia.
American Journal of Medical Genetics - Neuropsychiatric Genetics
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Williams, N.M. ORCID: https://orcid.org/0000-0001-7758-0312, Spurlock, G., Williams, H. ORCID: https://orcid.org/0000-0001-7758-0312, Norton, N., Walters, A., Saunders, R., Cardno, A.G., McCarthy, G., O'Donovan, M.C. ORCID: https://orcid.org/0000-0001-7073-2379 and Owen, M.J. ORCID: https://orcid.org/0000-0003-4798-0862
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Linkage disequilibrium mapping and candidate gene screening of the VCFS deleted region for mutations associated with schizophrenia.
American Journal of Medical Genetics - Neuropsychiatric Genetics
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Speight, G., Turic, Dragana, Austin, Jehannine, Hoogendoorn, Bastiaan ORCID: https://orcid.org/0000-0001-9753-169X, Cardno, Alistair, Jones, L., Murphy, K. C., Sanders, R., McCarthy, G., Jones, Ian Richard ORCID: https://orcid.org/0000-0001-5821-5889, McCandless, F., McGuffin, P., Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Buckland, Paul Robert and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
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Comparative sequencing and association studies of aromatic L-amino acid decarboxylase in schizophrenia and bipolar disorder.
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10.1038/sj.mp.4000717
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Cheap, accurate and rapid allele frequency estimation of single nucleotide polymorphisms by primer extension and DHPLC in DNA pools.
Human Genetics
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Candidate-gene association studies of schizophrenia.
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ATP2A2 mutations in Darier's disease and their relationship to neuropsychiatric phenotypes.
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Optimal temperature selection for mutation detection by denaturing HPLC and comparison to single-stranded conformation polymorphism and heteroduplex analysis.
Clinical Chemistry
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CAG repeat length in the hKCa3 gene and symptom dimensions in schizophrenia.
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Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease.
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Analysis of CAG/CTG repeat size in Chinese subjects with schizophrenia and bipolar affective disorder using the repeat expansion detection method.
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Blind analysis of denaturing high-performance liquid chromatography as a tool for mutation detection.
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Further support for an association between a polymorphic CAG repeat in the hKCa3 gene and schizophrenia.
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Tryptophan pyrrolase gene expression in an alcohol preferring and non-preferring mouse strain.
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Linked polymorphisms upstream of exons 1 and 2 of the human cholecystokinin gene are not associated with schizophrenia or bipolar disorder.
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Association between functional psychosis and expanded CAG/CTG repeats is not explained by health stratification [comparative study].
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No evidence for expanded polyglutamine sequences in bipolar disorder and schizophrenia.
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Expanded CAG/CTG repeats in bipolar disorder: no correlation with phenotypic measures of illness severity.
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Exclusion of expansion of 50 CAG/CTG trinucleotide repeats in bipolar disorder.
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Exclusion of CAG/CTG trinucleotide repeat loci which map to chromosome 4 in bipolar disorder and schizophrenia.
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O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and Guy, C
1997.
Bias in the genomic distribution of CAG and CTG trinucleotide repeats.
American Journal of Medical Genetics
74
(1)
, pp. 62-64.
10.1002/(SICI)1096-8628(19970221)74:1<62::AID-AJMG14>3.0.CO;2-P
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Cardno, A. G., Murphy, K. C., Jones, L. A., Guy, C. A., Asherson, P., De Azevedo, M. H., Coelho, I. M., de Macedo e Santos, A. J., Pato, C. N., McGuffin, P., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
1996.
Expanded CAG/CTG repeats in schizophrenia. A study of clinical correlates.
British Journal of Psychiatry
169
(6)
, pp. 766-771.
10.1192/bjp.169.6.766
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O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Guy, Carol, Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610, Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, McKeon, P., Macedo, A., Maier, W., Wildenauer, D., Aschauer, H. N., Sorbi, S., Feldman, E., Mynett-Johnson, L., Claffey, E., Nacmias, B., Valente, J., Dourado, A., Grassi, E., Lenzinger, E., Heiden, A. M., Moorhead, S., Harrison, D., Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, McGuffin, P. and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862
1996.
Confirmation of association between expanded CAG/CTG repeats and both schizophrenia and bipolar disorder.
Psychological Medicine -London-
26
(6)
, pp. 1145-1153.
10.1017/s0033291700035868
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Bowen, Timothy ORCID: https://orcid.org/0000-0001-6050-0435, Guy, Carol, Speight, G., Jones, L., Cardno, A., Murphy, Kevin, McGuffin, P., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
1996.
Expansion of 50 CAG/CTG repeats excluded in schizophrenia by application of a highly efficient approach using repeat expansion detection and a PCR screening set.
American Journal of Human Genetics
59
(4)
, pp. 912-917.
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O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
1996.
Genetics of Mental disorders .1. Theoretical aspects - Mendlewicz,J, Papadimitriou,GN.
British Journal of Psychiatry
168
(2)
, p. 256.
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O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862
1996.
Dynamic mutations and psychiatric genetics.
Psychological Medicine
26
(1)
, pp. 1-6.
10.1017/S0033291700033663
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O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Guy, Carol, Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610, Murphy, Kevin, Cardno, Alastair G., Jones, L. A., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 and McGuffin, P.
1995.
Expanded CAG repeats in schizophrenia and bipolar disorder
[letter].
Nature Genetics
10
(4)
, pp. 380-381.
10.1038/ng0895-380
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Thapar, Anita ORCID: https://orcid.org/0000-0002-3689-737X, Gottesman, I. I., Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and McGuffin, P.
1994.
The genetics of mental retardation.
The British Journal of Psychiatry
164
(6)
, p. 747.
10.1192/bjp.164.6.747
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McGuffin, Peter, Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, O'Donovan, Michael Conlan ORCID: https://orcid.org/0000-0001-7073-2379, Thapar, Anita ORCID: https://orcid.org/0000-0002-3689-737X and Gottesman, Irving I.
1994.
Seminars in psychiatric genetics.
Gaskell, Royal College of Psychiatrists.
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Spurlock, G., Buckland, Paul Robert, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and McGuffin, P.
1994.
Lack of effect of antidepressant drugs on the levels of mRNAs encoding serotonergic receptors, synthetic enzymes and 5HT transporter.
Neuropharmacology
33
(3-4)
, pp. 433-440.
10.1016/0028-3908(94)90073-6
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Buckland, Paul Robert, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and McGuffin, Peter
1993.
Clozapine and sulpiride up-regulate dopamine D3 receptor mRNA levels.
Neuropharmacology
32
(9)
, pp. 901-907.
10.1016/0028-3908(93)90146-T
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McGuffin, P. and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
1993.
Taking a balanced view on triazolam.
British Medical Journal (BMJ)
306
(6893)
, pp. 1690-1691.
10.1136/bmj.306.6893.1690-c
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O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and McGuffin, P
1993.
Correction: Short acting benzodiazepines.
British Medical Journal (BMJ)
306
(6886)
, p. 1146.
10.1136/bmj.306.6886.1146
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O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and McGuffin, P
1993.
Short acting benzodiazepines.
British Medical Journal (BMJ)
306
(6883)
, pp. 945-946.
10.1136/bmj.306.6883.945
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Buckland, Paul Robert, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and McGuffin, Peter
1993.
Both splicing variants of the dopamine D2 receptor mRNA are up-regulated by antipsychotic drugs.
Neuroscience Letters
150
(1)
, pp. 25-28.
10.1016/0304-3940(93)90099-7
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O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Buckland, Paul Robert, Spurlock, Gillian and McGuffin, Peter
1992.
Bi-directional changes in the levels of messenger RNAs encoding γ-aminobutyric acidA receptor α subunits after flurazepam treatment.
European Journal of Pharmacology: Molecular Pharmacology
226
(4)
, pp. 335-341.
10.1016/0922-4106(92)90051-V
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O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Buckland, Paul Robert and McGuffin, Peter
1992.
Levels of GABAa receptor subunit mRNA in rat brain following flurazepam treatment.
Journal of Psychopharmacology
6
(3)
, pp. 364-369.
10.1177/026988119200600304
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Buckland, Paul Robert, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and McGuffin, Peter
1992.
Changes in dopamine D1, D2 and D3 receptor mRNA levels in rat brain following antipsychotic treatment.
Psychopharmacology
106
(4)
, pp. 479-483.
10.1007/BF02244818
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Buckland, Paul Robert, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and McGuffin, Peter
1992.
Changes in dopa decarboxylase mRNA but not tyrosine hydroxylase mRNA levels in rat brain following antipsychotic treatment.
Psychopharmacology
108
(1-2)
, pp. 98-102.
10.1007/BF02245292
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Buckland, Paul Robert, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and McGuffin, Peter
1992.
Lack of effect of chronic antipsychotic treatment on dopamine D5 receptor mRNA level.
European Neuropsychopharmacology
2
(4)
, pp. 405-409.
10.1016/0924-977X(92)90002-P
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O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379, Buckland, Paul Robert and McGuffin, P.
1992.
The expression of neuroreceptor genes and benzodiazepine tolerance.
Clinical Neuropharmacology
15
(Supp1)
, 218A-219A.
10.1097/00002826-199201001-00114
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O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and McGuffin, P
1991.
Growing points in psychiatric genetics.
British Journal of Hospital Medicine
46
(6)
, pp. 359-360.
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Havard, H. L., Buckland, Paul Robert, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and McGuffin, Peter
1991.
The effects of antidepressant drugs on kainate receptor mRNA levels.
Neuropharmacology
30
(6)
, pp. 675-677.
10.1016/0028-3908(91)90090-X
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O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and Buckland, Paul Robert
1991.
Simultaneous quantification of several mRNA species by solution hybridisation with oligonucleotides.
Nucleic Acids Research
19
(12)
, p. 3466.
10.1093/nar/19.12.3466
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Espie, C.A., Pashley, A.S., Bonham, K.G., Sourindhrin, I. and O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379
1989.
The mentally handicapped person with epilepsy: a comparative study investigating psychosocial functioning.
Journal of Mental Health Defiency Research
33
(2)
, pp. 123-135.
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